Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical Management

By: Martin H. Steinberg and Bernard G. Forget and Douglas R. Higgs and David J. Weatherall

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Synopsis: This book is a completely revised new edition of the definitive reference on disorders of hemoglobin. Authored by world-renowned experts, the book focuses on basic science aspects and clinical features of hemoglobinopathies, covering diagnosis, treatment, and future applications of current research. While the second edition continues to address the important molecular, cellular, and genetic components, coverage of clinical issues has been significantly expanded, and there is more practical emphasis on diagnosis and management throughout. The book opens with a review of the scientific underpinnings. Pathophysiology of common hemoglobin disorders is discussed next in an entirely new section devoted to vascular biology, the erythrocyte membrane, nitric oxide biology, and hemolysis. Four sections deal with α and β thalassemia, sickle cell disease, and related conditions, followed by special topics. The second edition concludes with current and developing approaches to treatment, incorporating new agents for iron chelation, methods to induce fetal hemoglobin production, novel treatment approaches, stem cell transplantation, and progress in gene therapy.

Book Quality:: Publisher Quality
ISBN-13:: 9780511594410
Related ISBNs:: 9780521875196, 9780511596186
Publisher:: Cambridge University Press
Date of Addition:: 10/13/10
Copyrighted By:: Cambridge University Press
Adult content:: No
Language:: English
Has Image Descriptions:: No
Categories:: Nonfiction, Science, Health, Mind and Body, Textbooks, Medicine
Grade Levels:: College Freshman, College Sophomore, College Junior, College Senior
Submitted By:: Bookshare Staff
Usage Restrictions:: This is a copyrighted book.