Actin Polymerization in Apicomplexan: A Structural, Functional and Evolutionary Analysis (1st ed. 2019)
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- Synopsis
- This book discusses in detail the structural, evolutionary and functional role of actin and its regulatory proteins in gliding motility in apicomplexan organisms, a unique phenomenon found in actin-myosin cytoskeletal elements. The book also explores the potential of different actin regulators, namely formin, profilin, actin depolymerization factor (ADF), capping proteins (CPα and CPβ), cyclase-associated protein (CAP) and coronin 13–24 as potential drug targets against malaria. As the chief components of the gliding motor, the actin-regulator proteins are characterized by unique features that make them promising targets for structure-based drug design. Lastly, the book proposes a mathematical model, based on kinetic data mining, to help understand the most vital regulators for actin polymerization dynamics.
- Copyright:
- 2019
Book Details
- Book Quality:
- Publisher Quality
- ISBN-13:
- 9789811374500
- Related ISBNs:
- 9789811374494
- Publisher:
- Springer Singapore, Singapore
- Date of Addition:
- 11/24/19
- Copyrighted By:
- Springer
- Adult content:
- No
- Language:
- English
- Has Image Descriptions:
- No
- Categories:
- Nonfiction, Science, Sports, Medicine
- Submitted By:
- Bookshare Staff
- Usage Restrictions:
- This is a copyrighted book.
- Edited by:
- Avinash Kale