Targeted Protein Degradation: Methods and Protocols (1st ed. 2021) (Methods in Molecular Biology #2365)

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Synopsis
This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Targeted Protein Degradation: Methods and Protocols aims to ensure successful results in this emerging field of drug discovery.
Copyright:
2021

Book Details

Book Quality:
Publisher Quality
ISBN-13:
9781071616659
Related ISBNs:
9781071616642
Publisher:
Springer US
Date of Addition:
Copyrighted By:
Springer Science+Business Media, LLC, part of Springer Nature
Adult content:
No
Language:
English
Has Image Descriptions:
No
Categories:
Nonfiction, Science, Medicine
Submitted By:
Bookshare Staff
Usage Restrictions:
This is a copyrighted book.
Edited by:
Angela M. Cacace
Edited by:
Christopher M. Hickey
Edited by:
Miklós Békés

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