Neurotrophic Natural Products (1st ed. 2024) (Progress in the Chemistry of Organic Natural Products #123)
By: and and and and and
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- Synopsis
- This book deals with neurotrophins (NGF, BDNF, NT3, NT4), which can decrease cell death, induce differentiation, as well as sustain the structure and function of neurons. This makes neurotrophins potential therapeutic agents for the treatment of neurodegenerative disorders. However, these proteins have so far been ineffective in clinical trials mostly because they cannot pass the blood-brain barrier owing to their high-molecular weights. Consequently, small molecules that mimic neurotrophins and stimulate the synthesis of endogenous neurotrophins or enhance their neurotrophic actions are expected to be promising alternatives. Small-molecule natural products, which have been used in dietary functional foods or in traditional medicine over the course of human history, have potential to be developed as new therapeutic agents against neurodegenerative conditions such as Alzheimer’s disease. In this book, the authors introduce a variety of natural products possessing neurotrophic properties such as neurogenesis, neurite outgrowth promotion (neuritogenesis), and neuroprotection and focus on the chemistry and biology of several neurotrophic natural products.
- Copyright:
- 2024
Book Details
- Book Quality:
- Publisher Quality
- ISBN-13:
- 9783031424229
- Related ISBNs:
- 9783031424212
- Publisher:
- Springer Nature Switzerland
- Date of Addition:
- 03/13/24
- Copyrighted By:
- The Editor
- Adult content:
- No
- Language:
- English
- Has Image Descriptions:
- No
- Categories:
- Nonfiction, Science, Medicine
- Submitted By:
- Bookshare Staff
- Usage Restrictions:
- This is a copyrighted book.
- Edited by:
- A. Douglas Kinghorn
- Edited by:
- Heinz Falk
- Edited by:
- Simon Gibbons
- Edited by:
- Yoshinori Asakawa
- Edited by:
- Ji-Kai Liu
- Edited by:
- Verena M. Dirsch
Reviews
Other Books
- by A. Douglas Kinghorn
- by Heinz Falk
- by Simon Gibbons
- by Yoshinori Asakawa
- by Ji-Kai Liu
- by Verena M. Dirsch
- in Nonfiction
- in Science
- in Medicine