Lymphoma: Methods and Protocols (Third Edition 2025) (Methods in Molecular Biology #2865)

By: Ralf Küppers

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Synopsis: This detailed volume expands upon the previous edition with key methods currently used in lymphoma research, partly specific for lymphoma research but often adaptable to the study of other cancers. New chapters explore the latest approaches for single cell B cell and T cell receptor sequencing, multiplexed immunophenotyping of lymphoma tissue samples, genetic manipulation and extended culture of human germinal center B cells, genetic mouse models of lymphomas, establishment of patient-derived xenograft models of lymphomas, and more. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-day, Lymphoma: Methods and Protocols, Third Edition serves as a valuable resource for hematologists, hematopathologists, and scientists interested in a variety of topics in cancer research, human genetics, and immunology.