Drug Metabolizing Enzymes: Cytochrome P450 and Other Enzymes in Drug Discovery and Development (1)
By: and and
Sign Up Now!
Already a Member? Log In
You must be logged into Bookshare to access this title.
Learn about membership options,
or view our freely available titles.
- Synopsis
- Critical in the elimination of drugs and other xenobiotics from the body, cytochrome P450 has strong bearing on scientific assessments of genetic polymorphism in metabolism, possible drug-drug interactions, and bioavailability of candidate drugs. This text systematizes findings on P450 and similar enzymes--as well as parallel issues shaping the pharmaceutical industry--to promote the next generation of safer, more effective drugs. Topics include dioxygen activation, the identification and characterization of metabolites, bioactivation, P450 in lab animal species, enzyme kinetics, reaction phenotyping, drug-drug interactions, pharmacogenetics, hepatic clearance, and the role of UGTs.
- Copyright:
- 2003
Book Details
- Book Quality:
- Publisher Quality
- Book Size:
- 608 Pages
- ISBN-13:
- 9781040199534
- Related ISBNs:
- 9780824742935, 9781420028485, 9780429118708
- Publisher:
- CRC Press
- Date of Addition:
- 01/30/25
- Copyrighted By:
- Taylor & Francis Group, LLC
- Adult content:
- No
- Language:
- English
- Has Image Descriptions:
- No
- Categories:
- Nonfiction, Science, Medicine
- Submitted By:
- Bookshare Staff
- Usage Restrictions:
- This is a copyrighted book.
- Edited by:
- null Jae Lee
- Edited by:
- null R. Scott Obach
- Edited by:
- null Michael B. Fisher
Reviews
Other Books
- by Jae S. Lee
- by R. Scott Obach
- by Michael B. Fisher
- in Nonfiction
- in Science
- in Medicine