Neural Transplantation Methods

By: Stephen B. Dunnett and Alan A. Boulton and Glen B. Baker

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Synopsis: Leading experimental neurobiologists and neurosurgeons provide all the technical and practical information required to perform neural transplantation in experimental and neurological research, including a detailed consideration of the issues involved in designing and customizing such methods for specific research purposes. The authors outline the different sources of donor tissues and other materials for implantation, review the different techniques for tissue implantation into the brains of experimental animals of different species, and detail the major factors for promoting graft survival, integration, and function. All the techniques are presented in a proven format, along with alternative methods for special experimental needs. Neural Transplantation Methods constitutes the single most comprehensive sourcebook of practical information on the effective use of transplantation techniques in experimental neurobiology. Its powerful and flexible techniques will significantly aid all those now working to develop today's powerful new treatments of brain and spinal cord diseases and injuries.