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Muscarinic Receptors
by Neil M. Nathanson Arthur Christopoulos Allison D. FryerMuscarinic acetylcholine receptors have played a key role in the advancement of knowledge of pharmacology and neurotransmission since the inception of studies in these fields, and the effects of naturally occurring drugs acting on muscarinic receptors were known and exploited for both therapeutic and non-therapeutic purposes for hundreds of years before the existence of the receptors themselves was recognized. This volume presents a broad yet detailed review of current knowledge of muscarinic receptors that will be valuable both to long-time muscarinic investigators and to those new to the field. It describes the detailed insights that have been obtained on the structure, function, and cell biology of muscarinic receptors. This volume also describes physiological analyses of muscarinic receptors and their roles in regulating the function of the brain and of a variety of peripheral tissues. This volume shows how the study of muscarinic receptors continues to provide new and surprising insights not just to the cholinergic system but to the broad areas of neurobiology, cell biology, pharmacology, and therapeutics.
Muscle Biophysics
by Rassier Dilson J.EThe field of muscle biophysics has changed dramatically over the past years and new studies are reshaping the way we think muscles contract. Rapidly evolving techniques and advances are allowing us to understand the mechanics of individual molecules and cells as we could never do so before. This book, a contributed volume of the work of several current opinion leaders and well-known scientists in the field, will be unique for its rich list of authors as well as its updated, comprehensive inclusion of techniques in both cell and molecular biophysiology.
Muscle Gene Therapy
by Dongsheng DuanMuscle disease represents an important health threat to the general population. There is essentially no cure. Gene therapy holds great promise to correct the genetic defects and eventually achieve full recovery in these diseases. Significant progresses have been made in the field of muscle gene therapy over the last few years. The development of novel gene delivery vectors has substantially enhanced specificity and efficiency of muscle gene delivery. The new knowledge on the immune response to viral vectors has added new insight in overcoming the immune obstacles. Most importantly, the field has finally moved from small experimental animal models to human patients. This book will bring together the leaders in the field of muscle gene transfer to provide an updated overview on the progress of muscle gene therapy. It will also highlight important clinical applications of muscle gene therapy.
Muscles of Chordates: Development, Homologies, and Evolution
by Rui Diogo Janine M. Ziermann Julia Molnar Natalia Siomava Virginia AbdalaChordates comprise lampreys, hagfishes, jawed fishes, and tetrapods, plus a variety of more unfamiliar and crucially important non-vertebrate animal lineages, such as lancelets and sea squirts. This will be the first book to synthesize, summarize, and provide high-quality illustrations to show what is known of the configuration, development, homology, and evolution of the muscles of all major extant chordate groups. Muscles as different as those used to open the siphons of sea squirts and for human facial communication will be compared, and their evolutionary links will be explained. Another unique feature of the book is that it covers, illustrates, and provides detailed evolutionary tables for each and every muscle of the head, neck and of all paired and median appendages of extant vertebrates. <P><P> Key Selling Features: <li>Has more than 200 high-quality anatomical illustrations, including evolutionary trees that summarize the origin and evolution of all major muscle groups of chordates <li>Includes data on the muscles of the head and neck and on the pectoral, pelvic, anal, dorsal, and caudal appendages of all extant vertebrate taxa <li>Examines experimental observations from evolutionary developmental biology studies of chordate muscle development, allowing to evolutionarily link the muscles of vertebrates with those of other chordates <li>Discusses broader developmental and evolutionary issues and their implications for macroevolution, such as the links between phylogeny and ontogeny, homology and serial homology, normal and abnormal development, the evolution, variations, and birth defects of humans, and medicine.
Mush: A Dog from Space
by Daniel PinkwaterLassie, Go Home -- Mush Is Here!Now that Kelly Mangiaro's family has moved out of their apartment into a house, she figures her parents will finally let her get a dog. Instead, her mother gets a job, and Kelly gets a baby-sitter. Then Kelly comes upon Mush, a mushamute -- a breed not recognized by the Westminster Kennel Club, or by anyone else for that matter, possibly because mushamutes come from the planet Growf-Woof-Woof, in the solar system of Arfturus. Mushamutes can talk, tell time, cook up a storm, and even clean up the kitchen afterwards. Who needs a baby-sitter when there's a mushamute around? Now if only Kelly can persuade her parents to let her keep Mush. . . .
Mushroom Wanderland: A Forager's Guide To Finding, Identifying, And Using 25 Wild Fungi
by Jess StarwoodThe breathtaking beauty of mushrooms from a master forager: how to identify and use them in cooking, home remedies, and spirituality. Foraging for mushrooms is a meditative and rewarding escape. Even if readers aren’t ready to head out into the woods, this enchanting visual guide is a welcome introduction to 25 easily identifiable species, organized by location and use. Author Jess Starwood has led hundreds of foraging trips, sharing her knowledge of nature with students. This, her first book, is a celebration of fungi—perfect for both beginner and longtime mushroom admirers. No matter their use, all mushrooms have specific characteristics that are easy to recognize with the right teacher. Under Starwood’s guidance, readers will learn to identify caps, stipes, gills, and pores. They’ll encounter species such as Reishi, Lion’s Mane, Candy Cap, Chanterelle, and more; learn the best harvesting seasons; and enjoy delicious recipes using culinary favorites. But, above all, this guide will have readers growing their connection to nature and dreaming of the wonderful world of fungi.
Mush's Jazz Adventure
by Daniel PinkwaterNow that Mush -- the talking, cooking, educated dog from space -- is part of the Mangiaro household, Kelly wants to know more about the planet Growf-Woof-Woof, and how her dog came to Earth. When the two of them go on a picnic, (which Kelly prepares carefully under Mush's supervision), Kelly asks Mush about her past. "Well, it's such a long story," says Mush. . . and soon, Kelly is hearing about Mush's old jazz band, The Hot Animals, and how they dealt with robbers who threatened to knock over their boss's jive joint!
Music for Tigers
by Michelle Kadarusman“Middle-school student Louisa wants to spend the summer practicing violin for a place in the youth symphony, but is instead sent to the Tasmanian rain forest camp of her Australian relatives. There she learns that her family secretly protects the last of the supposedly extinct Tasmanian tigers. When an encroaching mining operation threatens the hidden sanctuary, Louisa realizes her music can help” - Provided by publisher.
The Music of Dolphins (Apple Signature Edition Ser.)
by Karen Hesse“This powerful exploration of how we become human and how the soul endures is a song of beauty and sorrow, haunting and unforgettable.” —School Library Journal (starred review)A Publishers Weekly Best Book of the YearA School Library Journal Best Book of the YearAn ALA Best Book for Young AdultsA Book Links Best Book of the YearA New York Public Library Children’s Title for Reading and SharingMila becomes famous around the world when she is rescued from an unpopulated island off the coast of Florida. Years ago, Mila went missing from a boat crash, and she has been raised by dolphins from the age of four.Researchers teach Mila language and music. But she also learns about rules and expectations, about locked doors and broken promises, disappointment and betrayal.The more Mila finds out about what it means to be human, the more she longs for her home in the ocean . . . “As moving as a sonnet, as eloquently structured as a bell curve, this book poignantly explores the most profound of themes—what it means to be human . . . All together, a frequently dazzling novel.” —Publishers Weekly (starred review)“Her mind and spirit shaped by the dolphins who raised her, a feral child views herself and her human captors from a decidedly unusual angle in this poignant story . . . A probing look at what makes us human, with an unforgettable protagonist.” —Kirkus Reviews“Mila’s rich inner voice makes her a lovely, lyrical character.” —VOYA Magazine
The Music of Wild Birds: An Illustrated, Annotated, and Opinionated Guide to Fifty Birds and Their Songs
by Judy Pelikan F. Schuyler MathewsOne hundred years ago, F. Schuyler Mathews, an erudite naturalist and birder, theorized that birds sing first for love of music, and second for love of the lady. To expand on his theory, he actually scored the songs of birds in the wild. His charming text and bird-by-bird annotations were compiled into a guide called Field Book of Wild Birds and Their Music. This extraordinary work has now been lavishly illustrated and adapted for a new audience. Each bird is meticulously rendered by artist Judy Pelikan in full-color illustrations that feature not only the birds, but also their nests, eggs, and feathers. And every song is represented by its written musical score, which Mathews expertly explains in a way that both musicians and non-musicians can enjoy. As Mathews points out, the music of wild birds is everywhere--in poems, children's nursery songs, as well as in the works of the great composers: the Black-billed Cuckoo's call appears near the close of Beethoven's Pastoral Symphony; the Nashville Warbler's song is found in the opening bars of Rossini's Carovale, and the Meadowlark's song is remarkably like the first two bars of Alfredo's song in La Traviata. He reveals how a bird's character is reflected in its song: the Baltimore Oriole is a sharp-billed, sharp-witted character, and his remarks are as incisive and crisp as the toots of a steam whistle. And he reminds us of the words of our great poets--Wordsworth, Emerson, Sir Walter Scott--and their descriptions of the very same birds and their music. This classic, useful, and completely original guide will put a song into the heart of novice and experienced birder alike.
Musk Ox (Nature's Children)
by Tom JacksonDescribes the physical features, habits, and habitat of the largest Arctic grazer.
Muskrat for Supper
by Kenny SalweyMuskrat for Supper inspires young people to explore nature's life cycles and understand the concept of the circle of life, as told through the tale of a family that embarks on a hunting and trapping adventure. It is an endearing story that weaves together such themes as sustainable living, our natural environment, and living closer to nature. The first book for children by this acclaimed storyteller and author, Muskrat for Supper includes questions young people have asked Kenny Salwey about his lifestyle as a river rat living off the land. The story will be illustrated with black-and-white photographs as well as nonfiction material to supplement the text. Kenny Salwey is the last of a breed of men whose lifestyle has all but disappeared in this fast-paced, high-tech digital world. For thirty years, this weathered woodsman eked out a living on the Mississippi River running a trapline, hiring out as a river guide, digging and selling roots and herbs, and eating the food he hunted and fished. Today Salwey is a master storyteller, environmental educator, keynote speaker, nature writer, and advocate for the Upper Mississippi River. He has presented his true-life adventures and words of natural world wisdom to both adult and young audiences across the upper Midwest. By sharing his hard-learned experiences, his respect for the Mississippi River, and his love of the natural world, Salwey hopes to inspire his audiences to protect this precious and fragile ecosystem.
Muskrats (Nature's Children)
by Laima DingwallHave you ever wondered where the muskrat got its name? What it eats? And how it protects itself from danger? Explore this fascinating creature in this book.
Must Be Good Riders: Orphans Preferred
by Don Stanford Vern BakerSixteen-year-old David McKae arrives in the little Western town of Hall’s Station with a macabre load of fellow passengers aboard the Concord coach—five dead men. When David tells his grisly tale of ambush, robbery, and murder, a posse rides out to find the killer. David remains behind in Hall’s Station, friendless, penniless, and just about the loneliest and most bewildered young fellow in the territory. Born and bred in Gloucester, Massachusetts, David came West after the death of his father to find his uncle, and seek his own fortune. But as the battered stage rumbled its way across the Nevada desert, fate in the form of trigger-happy Johnny Hadley, a killer and a renegade, stepped in, and before the two coachmen and four passengers reached their scheduled destinations, five of the six were dispatched to a different and more final rendezvous—with Death. Only David McKae, the Easterner in his city clothes, survived. Recovering consciousness after being left for dead by the murderous Hadley, David managed to bring the coach into Hall’s Station. The luck that saved David from the gunman’s attack remains with him in the small Western town. Soon he is befriended by Doherty, a huge, kindly Irishman, and Dianne, Doherty’s half-Indian daughter. Doherty teaches David the ways of the West, and the ways of the Indians. One of the first lessons is on self-defense. He must get a gun, Doherty tells him, and he must learn to shoot it well. David also makes a friend of fourteen-year-old Billy Tate, a Pony Express rider, and is seized with the ambition to ride for the Pony. David has much to learn before he can join the ranks of the wily and courageous Pony riders. And before any of this can come to pass, David, though he does not know it, will be put to the test of his life—by the return of Johnny Hadley. Here is a story full of the lore—and the lure—of the old West, where life was at best a precarious affair, and the fearless boy riders of the Pony Express—not one of them over eighteen—answered the ominous description of its advertisements.
Must-See Birds of the Pacific Northwest: 85 Unforgettable Species, Their Fascinating Lives, and How to Find Them
by Sarah Swanson Max SmithMust-See Birds of the Pacific Northwest is a lively, practical guide that helps readers discover 85 of the region’s most extraordinary birds. Each bird profile includes notes on what they eat, where they migrate from, and where to find them in Washington and Oregon. Profiles also include stunning color photographs of each bird. Birds are grouped by what they are known for or where they are most likely to be found—like beach birds, urban birds, colorful birds, and killer birds. This is an accessible guide for casual birders, weekend warriors, and families looking for an outdoor experience. Eight easy-going birding weekends, including stops in Puget Sound, the Central Washington wine country, and the Klamath Basin, offer wonderful getaway ideas and make this a must-have guide for locals and visitors alike.
Mustache Duckstache
by Amy YoungThe zany humor of Aaron Reynolds meets some serious facial hair in this competition for the title of finest mustache in the land!When a mustachioed rabbit spots a mustache contest, he's sure he has the competition beat. That is, until a pesky frog hops up with his own fine mustache. And a duck waddles up with a...duckstache? Soon, the competition is full of moosestaches and mousestaches, whalestaches and tailstaches--and every kind of 'stache in between. Readers will love following this simple tale of hirsute havoc with a laugh-out-loud twist ending. Plus, there's a fun guide at the end to every kind of mustache imaginable!
Mustang: Wild Spirit of the West (Marguerite Henry Horseshoe Library)
by Marguerite HenryHorses were in Annie Bronn’s blood. For as long as she could remember, she had been fascinated by the spirited wild mustangs that roamed free throughout the West. So when greedy cattlemen started to round up the mustangs for slaughter, Annie knew it was up to her to save the breed.The true story of Wild Horse Annie’s crusade to save the mustangs is inspiring. Readers will cheer her on, all the way to the White House, in her struggle to preserve these beautiful creatures from extinction.
Mustang: A Horse of the Old West (Famous Horse Stories)
by Thomas C. HinkleMUSTANG! The pride of his rancher owner, Mustang was stolen by a wandering cowboy and traded from hand to hand. Nobody could touch spur to him. Swift as the wind, the big bay won the only race he entered -- and kept on running, back to the open range. He wanted no more of men. Then, trapped by horse hunters, chased by cowboys eager for his capture, Mustang finally rejoined his owner in a desperate race with a blizzard. A classic western novel by one of the most acclaimed western authors of his day.
Mustang: The Saga of the Wild Horse in the American West
by Deanne Stillman“A fascinating narrative with all the grace and power embodied in the wild horses that once populated the Western range . . . [A] magnificently told saga.” —Albuquerque JournalA Los Angeles Times Best Nonfiction Book of the YearMustang is the sweeping story of the wild horse in the culture, history, and popular imagination of the American West. It follows the wild horse across time, from its evolutionary origins on this continent to its return with the conquistadors, its bloody battles on the old frontier, its iconic status in Buffalo Bill shows and early westerns, and its plight today as it makes its last stand on the vanishing range. With the Bureau of Land Management proposing to euthanize thousands of horses and ever-encroaching development threatening the land, the mustang’s position has never been more perilous. But as Stillman reveals, the horses are still running wild despite all the obstacles, with spirit unbroken.Hailed by critics nationwide, Mustang is “brisk, smart, thorough, and surprising” (Atlantic Monthly).“Like the best nonfiction writers of our time (Jon Krakauer and Bruce Chatwin come to mind), Stillman’s prose is inviting, her voice authoritative and her vision imaginative and impressively broad.” —Los Angeles Times“Powerful . . . Stillman’s talent as a writer makes this impossible [to stop reading], to the mustang’s benefit.” —Orion“A circumspect writer passionate about her purpose can produce a significant gift for readers. Stillman’s wonderful chronicle of America’s mustangs is an excellent example.” —The Seattle Times
The Mustang (Endangered In America)
by Alvin Silverstein Virginia Silverstein Laura Silverstein NunnFrom the book: ENDANGERED IN AMERICA More than 300 kinds of North American animals are listed as endangered or threatened-at risk of dying out. But people are taking action to help them, sometimes with remarkable success. These books present the stories of some of these animals, and of the efforts to save them.
Mustang Flats
by G. Clifton WislerWhen his father returns from the war in 1865, fourteen-year-old Alby finds his beloved Pa a changed man and can only hope that they will be friends again.
Mustang in the Mist (Animal Ark #59)
by Ben M. BaglioMandy and James are excited to help with a team of mustangs and a rock video, but must nurse the lead horse, Cougar, back to health after he develops a strange, life-threatening illness.
Mustang Moon (Phantom Stallion #2)
by Terri FarleyThe beloved second book in the middle grade Phantom Stallion series about a girl, her horse, and the beauty of the American West returns with a brand-new, stunning cover and bonus material! Perfect for fans of Canterwood Crest and classic horse stories like Black Beauty and My Friend Flicka.Sam has befriended the mysterious, powerful mustang known as the Phantom, and she&’s determined to defend his freedom on the open range. But when tame mares start going missing from local ranches, the Phantom becomes the number one suspect—and there&’s one rancher who would use any excuse to capture the wild white stallion. When a reward is offered to anyone who can bring the Phantom in, Sam is no longer just fighting for his freedom—she&’s fighting for his life.
Mustangs and Wild Horses (Learning About Horses)
by Gail B. StewartThe author discusses the Mustangs of the west, where they came from, how they survive and their battles with ranchers for existence.