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Kawasaki Disease
by Ho-Chang KuoThis book aims to provide readers with up-to-date information on clinical research, diagnostic methods and treatment choice of Kawasaki disease. First chapters describe clinical symptoms, diagnosis, treatment, and complications of Kawasaki disease. Hot topics of precision medicine, big data analysis, genetics study, psychologic problems and allergic diseases after Kawasaki diseases are also discussed in details. Written by experts with wealthy experience in the field, this book will be an invaluable reference for pediatricians and clinicians working in the field of Kawasaki disease.
Clinical Decision Making for Improving Prognosis
by Rong LiuWith the advent of artificial intelligence and big data era, a new concept of clinical decision making for improving prognosis was proposed, which emphasizes the optimal prognosis and best outcome for patients, makes full use of information technology such as artificial intelligence to reduce the uncertainty in the treatment process and the unevenness of the treatment level, and selects the most appropriate intervention means and intervention timing through objective evaluation. It will be helpful for surgeons to choose treatment options which will be effective to patients.
Lymphocyte Immunization Therapy (LIT) in Reproductive Failures: New Horizons
by Mohan Raut Mugdha RautRecurrent Miscarriages (RM) & Implantation Failure (IF) have remained an enigma to clinicians and researchers. Even after ruling out all possible causative factors, 50-60% cases still remain “Unexplained’. A majority of these so called “Unexplained” cases are now found to have immunological basis.This book is going into the Immunological aspects of these clinical dilemmas, demystifying the role of Immunology and Immunotherapy in RM and IF. The authors have been working in the field of Reproductive Immunology and Immunotherapy for the last 25 years and they have come out with this book combining the international studies with their own experience. The purpose of writing this book is to provide a comprehensive treatise about Immunotherapy, so that it can become an acceptable modality of treatment in cases where it is needed and is effective.The book discusses the basics in Reproductive Immunology. The immunological changes occurring during pregnancy, the role of Cell mediated Immunity (T cells), Humoral Immunity including cytokines is explained. The normal immunological mechanisms protecting the embryo are highlighted and how these mechanisms are disturbed leading to RM and IF, is also explained.The first and the most discussed method of Immunotherapy is Lymphocyte Immunization Therapy (LIT). The book has given a complete overview of LIT, describing how it created euphoria when it was first introduced, how it gradually went into disrepute and how it is now making a comeback. As the authors have personal experience of LIT, the book gives a detailed and complete information about this active form of immunotherapy.The book has a special section on case studies where the authors have given some clinical case reports (including some of their own), who were treated for immunological factor in RM/IF and were treated with Immunotherapy. These cases can be a useful guide to the readers.The book will be useful not only for undergraduate and postgraduate students but also for clinicians in their practice and for researchers for review of developments in the field.
Conflict, Culture and Identity in GP Training
by Jennifer L. JohnstonThis book explores the identity work and conflicted perspectives of general practitioner (GP) trainees working in hospitals in the UK. Drawing on empirical and theoretical scholarship, and privileging the analysis of social language-in-use, Johnston describes primary care medicine as a separate paradigm with its own philosophy, identity and practice. Casting primary and secondary care in historical conflict, the perceived lower status of primary care in the world of medicine is explored. Significant identity challenges ensue for GP trainees positioned at the coalface of conflict. Problematising structures of GP training and highlighting how complex historical power dynamics play out in medical training, the author advocates for radical change in how GPs are trained in order to manage the current primary care recruitment and retention crisis.
Blockchain in Life Sciences (Blockchain Technologies)
by Wendy CharlesThis book highlights the latest advances on the implementation and adaptation of blockchain technologies in real-world scientific, biomedical, and data applications. It presents rapid advancements in life sciences research and development by applying the unique capabilities inherent in distributed ledger technologies. The book unveils the current uses of blockchain in drug discovery, drug and device tracking, real-world data collection, and increased patient engagement used to unlock opportunities to advance life sciences research. This paradigm shift is explored from the perspectives of pharmaceutical professionals, biotechnology start-ups, regulatory agencies, ethical review boards, and blockchain developers. This book enlightens readers about the opportunities to empower and enable data in life sciences.
Evolution of Digitized Societies Through Advanced Technologies (Advanced Technologies and Societal Change)
by Amitava Choudhury T. P. Singh Arindam Biswas Mrinal AnandThis book provides an understanding of the evolution of digitization in our day to day life and how it has become a part of our social system. The obvious challenges faced during this process and how these challenges were overcome have been discussed. The discussions revolve around the solutions to these challenges by leveraging the use of various advanced technologies. The book mainly covers the use of these technologies in variety of areas such as smart cities, healthcare informatics, transportation automation, digital transformation of education. The book intends to be treated as a source to provide the systematic discussion to the bouquet of areas that are essential part of digitized societies. In light of this, the book accommodates theoretical, methodological, well-established, and validated empirical work dealing with various related topics.
Menstrual Bodies and Gender: The Transnational Business of Menstruation from Latin America
by Eugenia TarzibachiThis book interrogates how the so-called “Feminine Care” industry travelled from the United States to Latin America via manufactured and disposable menstrual management technologies and certain narratives about menstrual bodies. The author focuses on Argentina as a case study to deepen the analysis of transnational politics and business practices around menstruation, drawing on women’s voices to unveil why menstruation is still a bodily process that is natural yet taboo in Latin America. This fascinating volume is a must-read for anyone interested in how the “Feminine Care” industry helped reify the insidious social mandate of shame and secrecy over women’s bodily experiences.
Ageing with Dignity in Hong Kong and Asia: Holistic and Humanistic Care (Quality of Life in Asia #16)
by Vincent Tin Sing Law Ben Yuk Fai FongThis book advocates the application of holistic and humanistic approaches in elderly care and services to achieve the goal of ageing with dignity in Hong Kong and Asia. It responds to the needs of an increasing ageing population that has to deal with related health needs in long-term care, community health and social services, particularly for chronic conditions and psychosocial support. The book consists of three sections on policy and development of aged care, holistic and humanistic care for older adults, and capacity building for ageing with dignity, respectively. Topics include the latest initiatives in aged care, appropriate services and delivery models, lifestyle modification, psychosocial and environmental considerations, professional development, technologies, and social capital. The chapters review and discuss these issues within a global context, illustrated by examples from Asian countries, underpinned by locally based empirical research. Contributors include academics and practitioners from diversified professional backgrounds that include medicine, nursing, pharmacy, traditional Chinese medicine, dietetics, and allied health. The book traverses into territories in the social sciences, life sciences, and sports sciences, while also touching on areas of business and administration, hospitality, law, public policy, and information technology in connection with public health. The contents serve as a topical reference for tertiary studies in ageing and related disciplines such as well-being and are also useful to policymakers, community and public health practitioners, health executives and interns working in areas of policy and practice pertinent to care development, health delivery models, planning, quality, ethics, better health promotion, professional training, and monitoring for older adults.
Frontier Technologies in Bovine Reproduction
by A. Kumaresan A. K. SrivastavaThis book details the frontier technologies in the area of bovine reproduction. It describes the importance and significance of different technologies for improving reproduction efficiency in bovines. The book delineates the advancements in the technologies that are currently in use for faster multiplication of elite germ plasm including multiple ovulation and embryo transfer, ovum-pick-up, in vitro fertilization and embryo production, and semen sexing. Other emerging technologies, having potential for improving reproductive efficiency in bovines, including stem cells are also discussed with special reference to spermatogonial stem cells. Simple but effective tools having a great scope for day-to-day application in bovine farms for effective reproductive management like ultrasonography and thermal imaging are also covered in this book. The chapters on sperm transcriptomics, proteomics, metabolomics provide current developments in these areas and use of integrated approach for identification of fertility biomarkers. The chapters also describe technological advancements for early pregnancy diagnosis and offspring sex pre-selection in bovines. Additionally, this book discusses different sperm selection procedures including application of nanotechnology to obtain superior spermatozoa for assisted reproduction. Futuristic technologies including genomic selection and transgenesis are also discussed in detail. Finally, the book also elucidates a comprehensive description of challenges perceived with bovine reproduction and how effectively these technologies can help in improving fertility in bovines.
Healthcare System Management: Methods and Techniques
by S. D. GuptaThe book discusses concepts and theories of general management and their specific applications related to public health and health care. Each chapter highlights the ideas and usefulness of different approaches in the context of health management. It addresses problems in different areas of healthcare systems management. It offers solutions in improving the performance, efficiency, and effectiveness of health programs and systems. Some of the topics covered in the book include health systems and policy, epidemiology, biostatistics, population dynamics, health economics and finance, logistics and supply chain, health research, health communication, quality management in health, and legal and ethical issues in health. The book serves as an indispensable resource for the faculties and students of health management or public health globally as well as healthcare professionals and researchers.
Sub-Terahertz Sensing Technology for Biomedical Applications (Biological and Medical Physics, Biomedical Engineering)
by Shiban Kishen Koul Priyansha KauravThis book offers the readers an opportunity to acquire the concepts of artificial intelligence (AI) enabled sub-THz systems for novel applications in the biomedical field. The readers will also be inspired to contextualize these applications for solving real life problems such as non-invasive glucose monitoring systems, cancer detection and dental imaging. The introductory section of this book focuses on existing technologies for radio frequency and infrared sensing in biomedical applications, and their limited use in sensing applications, as well as the advantages of using THz technology in this context. This is followed by a detailed comparative analysis of THz electronics technology and other conventional electro optic THz setups highlighting the superior efficiency, affordability and portability of electronics-based THz systems. The book also discusses electronic sub-THz measurement systems for different biomedical applications. The chapters elucidate two major applications where sub-THz provides an edge over existing state of the art techniques used for non-invasive measurement of blood glucose levels and intraoperative assessment of tumor margins. There is a detailed articulation of an application of leveraging machine learning for measurement systems for non-invasive glucose concentration measurement. This helps the reader relate to the output in a more user-friendly format and understand the possible use cases in a more lucid manner. The book is intended to help the reader learn how to build tissue phantoms and characterize them at sub-THz frequencies in order to test the measurement systems. Towards the end of the book, a brief introduction to system automation for biomedical imaging is provided as well for quick analysis of the data. The book will empower the reader to understand and appreciate the immense possibilities of using electronic THz systems in the biomedical field, creating gateways for fueling further research in this area.
Responsible Innovation in Health: Concepts and Tools for Sustainable Impact
by Pascale Lehoux Lysanne Rivard Hudson P. SilvaThis book introduces the field of Responsible Innovation in Health (RIH) by clarifying its theoretical foundations and the practical approaches that enable the design and production of responsible medical devices, health and social care interventions, digital tools and solutions based on artificial intelligence. It brings a lasting impact on the ways innovation stakeholders think about and develop solutions to twenty-first century challenges, including the Sustainable Development Goals (SDGs).
Current Concept in Cleft Surgery: Moving Toward Excellence of Outcome and Reducing the Burden of Care
by Rafael Denadai Lun-Jou LoThis book intends to cover cleft-related topics which are mainly focused on the current concept of balancing excellence in outcome and burden of cleft care. The wide spectrum of covered topics includes the understanding challenges and needs to deliver the modern surgical cleft care worldwide and comprehending multidisciplinary-based longitudinal life-changing concept. The chapters are focused on professional-friendly technical descriptions from diagnosis to execution such as nasoalveolar molding, cleft lip repair, cleft palate repair, myringotomy tube insertion, primary and secondary rhinoplasties, oronasal fistula reconstruction, velopharyngeal insufficiency management, virtual-aided alveolar reconstruction, surgery-first approach in cleft orthognathic surgery, 3D computer-assisted orthognathic surgery, revisionary surgeries, and postoperative care. Traditional and current principle-based methods are itemized into many algorithms and protocols to aid in diagnosing, planning, and selecting the best therapeutic approach in order to balance excellence in outcome and burden of care. Many surgical-, orthodontic-, speech-, and postoperative care-related technical examples, intraoperative photos, and full-colour illustrative drawings can guide the professionals working in multidisciplinary teams through each traditional and newer hybrid operative procedure in a detailed step-by-step fashion with emphasis on how to perform each procedure, rather than on theoretical-only descriptions. This book provides time- and scientifically-tested treatment algorithms to guide multidisciplinary teams during decision making process for each clinical scenario of the longitudinal cleft care
Cross-Sectional Atlas of Rhesus Monkey Head: with 0.024-mm pixel size color images
by Jin Seo ParkThe Visible Monkey is the first trial to obtain high-quality and real-color sectioned images of a rhesus monkey’s whole body (intervals, 0.05 mm (head) and 0.5 mm (body except head); pixel size, 0.024 mm X 0.024 mm; color depth, 48 bits color). This color atlas sets a new standard in rhesus monkey neuroanatomy by presenting around 400 ultrathin sectioned images of the head, including the brain, and whole body of the rhesus monkey. The image enabled observations of detailed anatomical structures, thanks to high-resolution and real-color sectioned images of the monkey unlike the stained sections and magnetic resonance images (MRI). Furthermore, anterior commissure-posterior commissure reference system employed for this purpose is clearly explained for the readers, and structures are fully annotated in the horizontal, coronal, and sagittal planes. Recent advances in 3 Tesla MRI and tractography from MRI have considerably enhanced imaging of the monkey brain, thereby impacting on both neuroscience research and clinical practice. Moreover, the information gained from initiatives involving photography of thin slices of cross-sectional images includes enriched knowledge of neuroanatomy and thereby facilitated the interpretation of such ultra-high-field resolution images. These exquisite images contained within this atlas will be invaluable in providing both researchers and clinicians with important new insights.
Therapeutic Applications of Mesenchymal Stem Cells in Veterinary Medicine
by Mudasir Bashir GugjooThis book reviews the potential therapeutic and reproductive applications of mesenchymal stem cells in veterinary regenerative and reproductive medicine. The systemic approach focuses on musculoskeletal structures like cartilage, bone, muscle, tendon, ligaments and nervous tissues. It also focuses on other body systems like gastrointestinal, cardiovascular, urogenital, respiratory and integumentary system. Besides, the special glands or organs like endocrine glands and eye and its adnexa are also focused. The book chapters discusses the problems and the need for regenerative medicine employing MSCs. It provides an ex vivo basis of MSCs therapeutics and reproductive potential followed by their in vivo applications. The book further provides an understanding on the behavior and mechanisms of action of mesenchymal stem cells. The book also abridges challenges and provides future prospects of mesenchymal stem cells in clinical and reproductive applications. As such, the book offers a valuable resource for students, veterinarians, and scientists working in the regenerative and reproductive sciences in human and veterinary medicine.
Textbook of Microbiology and Immunology
by Subhash Chandra ParijaThe fourth edition of “Textbook of Microbiology and Immunology” is an extensively revised edition , a healthy mixture of the old and the new contents. Many of the old traditional chapters have been retained with addition of new information along with the inclusion of new chapters more in line with the on-going changes in the syllabus and concepts in Medical Microbiology .While doing so, this book has blended the traditional organism-based learning and a syndrome based approach to infectious disease, together with the introduction of new and modified chapters incorporating the latest information in this field.The book provides an extensive coverage of fundamental topics in general and medical microbiology. The book also lays due emphasis on clinical microbiology with special focus on syndrome based approach to infectious diseases. It includes the basic concepts of microbiology as well as the recent updates and developments in the field of medical microbiology. All the topics have been incorporated in seven major sections: General microbiology, Immunology, Bacteriology, Virology, Mycology, and Applied and Clinical Microbiology.The dynamic nature of medical sciences with new guidelines and new diagnostic methods coming into the arena necessitates the incorporation of new information in each new edition of a book. This facet has been addressed with the inclusion of recent information on the various aspects of microbiology, infectious diseases and immunology, in the fourth edition of the Textbook of Microbiology and Immunology ,which makes it one of the most authoritative and informative textbooks in medical microbiology.The book is an effort to inform and engage a wide spectrum of readers including medical students , both undergraduates and postgraduates, and residents, and faculty. It aims to be a must-have companion book for graduate and advanced undergraduate as well as postgraduate students of medical microbiology, general and allied microbiology, and of immunology.
Atlas of Inflammatory Bowel Disease-Associated Intestinal Cancer: Examining the Macroscopic Images of Small and Large Intestine
by Toshiyuki Matsui Akinori Iwashita Takayuki Matsumoto Takashi Hisabe Kitaro Futami Hiroshi TanabeThis book is structured in three major parts and the first part is a comprehensive overview of IBD-related intestinal cancer. The second and third parts provide rare and important cases on ulcerative colitis (UD) and Crohn’s disease (CD) presenting the macroscopic image of the resected specimen and analyzing the endoscopic and the pathological image to explain how to find the IBD cancer. It also delivers a detailed analysis of the histological structure of cancers. This book tries to clarify the critical but yet to be answered questions such as “Why is it so difficult to find out?”, “Why so flat?” and “How to name superficial lesion with invisible margin?” and so on.Atlas of Inflammatory Bowel Disease-Associated Intestinal Cancer is designed to serve all endoscopists and gastroenterologists managing IBD patients. It also is valuable reading for pathologists who are diagnosing gastrointestinal lesions. This book is designed to assist these medical professionals to find cancers in the early stage and stay up-to-date on image-enhanced endoscopy techniques. This book is a translation of an original Japanese edition. This has been facilitated using machine translation (by the service DeepL.com) followed by editors and authors revising, editing and verifying the translated manuscript.
Towards Newborn Survival: Challenges and Priorities
by Sandhya R. MahapatroThis book offers a comprehensive study of the complexities of newborn survival in resource-poor regions, using the state of Bihar (India) as a case study. It provides important lessons for other low-performing countries, in similar socioeconomic contexts, where newborn survival is a major challenge.The volume opens with a brief account of the trends and regional variations in neonatal mortality. The empirical verification of socio-cultural, economic and health system barriers and the state interventions that affect newborn survival are subsequently explored. Innovative strategies are then proposed to scale up maternal newborn and child health (MNCH) services and improve neonatal health outcomes. Addressing this issue through appropriate policy action is essential to achieving Sustainable Development Goal-3, "Good Health and Well-being". This book will therefore appeal to public health scholars, professionals and policymakers interested in improving outcomes in low-income regions.
Maternal Mortality - Lessons Learnt from Autopsy
by Kusum D. JashnaniThe book discusses about 45 cases of maternal autopsies. These maternal mortalities are related to pregnancy-related diseases, pre-existing diseases that worsen or manifest during pregnancy and diseases for which pregnant patient has increased risk. As the study of maternal mortality is a healthcare quality indicator and plays an important role in the improvement of obstetric care, the book aims at discussing autopsy findings, which is the gold standard for establishing not only the causes of death, but also to uncover the various pathological lesions produced by the physiologic phenomenon of pregnancy. This helps in identifying the direct and indirect causes, which can be reviewed at multidisciplinary review meetings.The chapters are arranged according to direct and indirect causes of maternal death, involving varied target organ systems i.e. central nervous system, cardiovascular system, respiratory system, gastro-intestinal tract, hepato-biliary system and pancreas, urinary system, female genital tract and others. However, it does not include diseases coincidental in pregnancy.Each case begins with the complete case history (age, duration of pregnancy, clinical presentation, investigations, clinical diagnosis, therapy, and course during ward stay, if any), autopsy findings, followed by a clinico-pathological discussion and includes appropriate gross organ and microscopic images. The book caters to the specialists in pathology, obstetrics, general medicine, critical care, surgery, pulmonologists, cardiology and all those involved in the care of pregnant women.
Wilms’ Tumor
by Yogesh Kumar SarinThis book covers all aspects of Wilms’ tumor, the second most typical solid tumor in children. Its potential for complete cure underscores correct management of this tumor. To achieve this goal, the book aims to provide all necessary details for practicing Pediatric surgeons, Oncologists, Pediatricians, Urologists, and Medical students. Topics ranging from epidemiology, etiology, pathology, clinical features, diagnostic methods, surgery, chemotherapy, radiotherapy to cutting-edge inventions are described in great detail.Detailed descriptions of surgical techniques and their nuances will greatly benefit surgeons and surgical residents. Importantly, all the chapters are written by authors who have first-hand experience with clinical management. Thus the text ensures the practical application of theoretical details.
Innovation in Medicine and Healthcare: Proceedings of 10th KES-InMed 2022 (Smart Innovation, Systems and Technologies #308)
by Yen-Wei Chen Satoshi Tanaka Robert J. Howlett Lakhmi C. JainThis book presents the proceedings of the KES International Conferences on Innovation in Medicine and Healthcare (KES-InMed-22), held in Rhodes, Greece, on June 20–22, 2022. Covering a number of key areas, including digital IT architecture in health care; advanced ICT for medicine and health care; biomedical engineering, trends, research, and technologies; and healthcare support systems, this book is a valuable resource for researchers, managers, industrialists, and anyone wishing to gain an overview of the latest research in these fields.
Biophotonics: Concepts to Applications (Graduate Texts in Physics)
by Gerd KeiserThis book introduces senior-level and postgraduate students to the principles and applications of biophotonics. It also serves as a valuable reference resource or as a short-course textbook for practicing physicians, clinicians, biomedical researchers, healthcare professionals, and biomedical engineers and technicians dealing with the design, development, and application of photonics components and instrumentation to biophotonics issues. The topics include the fundamentals of optics and photonics, the optical properties of biological tissues, light-tissue interactions, microscopy for visualizing tissue components, spectroscopy for optically analyzing the properties of tissue, and optical biomedical imaging. It also describes tools and techniques such as laser and LED optical sources, photodetectors, optical fibers, bioluminescent probes for labeling cells, optical-based biosensors, surface plasmon resonance, and lab-on-a-chip technologies. Among the applications are optical coherence tomography (OCT), optical imaging modalities, photodynamic therapy (PDT), photobiostimulation or low-level light therapy (LLLT), diverse microscopic and spectroscopic techniques, tissue characterization, laser tissue ablation, optical trapping, and optogenetics. Worked examples further explain the material and how it can be applied to practical designs, and the homework problems help test readers’ understanding of the text.This second edition provides updates as follows:1) Updated references in each chapter with recent review papers, tutorials, and generic research results.2) New sections in Chap. 3 addressing tapered fibers for sensors, biocompatibility issues of optical fibers, and concepts of implantable fibers.3) Updates in Chaps. 4 and 5 on optical sources and photodetectors discussing fiber-based sources, silicon photomultipliers, and high-speed cameras for biosensing.4): Sections on improvements in microscopy, imaging, spectroscopy, and sensing in Chapters 7–10. 5) New biophotonic application techniques in Chap. 11 will include optogenetic advances, smart phones for imaging, wearable biophotonic sensors, and robotic surgery and light therapy.
Principles of Primary Total Hip Arthroplasty
by Yixin Zhou Jing Tang Hongyi ShaoThis book covers pertinent principles and practical surgical techniques related to primary total hip arthroplasty (THA) including complex cases. Written by experienced hip and knee surgeons, this book introduces the basic concepts of THA, helping the reader understand the basic science and history of THA. More chapters cover the preoperative planning and preparation, exposure using the various approaches, together with tips and tricks to position implants properly. Navigation-guided and robotic THA techniques are also included. Complications related to surgery, such as leg-length discrepancy, periprosthetic infections and fractures, hip instability, and deep vein thrombosis, are further discussed. Complex situations in specific diseases and pathology, such as rheumatoid hip arthritis, ankylosis spondylitis, and post-traumatic arthritic hip diseases are demonstrated.
When Was Arts in Health?: A History of the Present
by Frances WilliamsThis book critically appraises the field of Arts in Health in the light of the recent public health crisis and so-called culture wars. A new term was coined in Britain in 2017 for this area of work by an All-Party Parliamentary Group: “creative health”. Williams sets this hopeful assertion against a darker backdrop of austerity, rising inequality and “Covid-nationalism”. Understandings of the field as a (multi)national phenomenon are examined through contested narratives that surround its origin. Using genealogical methods, Williams shows how at supra, national and local policy levels, Arts in Health is presented as an idea that transcends place and time. Arguing against this premise, post-war decades are examined to reveal hidden, mutable arts-health expressions. Examples of practice, and their recognition as such, are context dependent it is concluded – produced by political economies as well as oppositional social movements.
UV-B Radiation and Crop Growth (Plant Life and Environment Dynamics)
by Sunita Kataria Vijay Pratap SinghThis book is an inclusive collection of topics on research on UVB for its impact on plants with a focus on its use as an emerging technology for crop growth and protection. This book covers role of UV-B on biological systems, and its transformation from generic stressor to specific regulator. It also explores the past research in UVB studies and the changing mind-sets regarding UV-B in recent time with respect to the plant growth. It also explores the discovery of specific UV-B photoreceptor, UVR8 and UVR8 mediated plants responses. This book is of interest to teachers, researchers, agriculture scientists and plant physiologists. Also the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, soil science, and environmental sciences