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Urine Formed Elements
by Lei Zheng Lizhi Yan Shimin ZhangThis book introduces the various urinary formed elements comprehensively, mainly including exfoliated cells, crystals and casts. Since the urinary formed elements are affected by various factors and their morphology may change, these components are identified by combining a variety of staining techniques. Various kinds of clinical classic cases are introduced, which are illustrated by richness high-definition colour pictures.
Down Syndrome Screening: A Practical Guide
by Abhijit KamatThe book elucidates a practical method for prenatal screening and detecting Down syndrome in a simple and easy-to-understand language. It provides thorough knowledge on the subject, and each chapter covers a specific topic, making this book an essential quick-reference guide for every antenatal clinic. The book contains chapters on maternal serum screening, noninvasive prenatal testing (NIPT), invasive testing with amniocentesis and CVS, and screening in twins. It also includes advanced chapters on multi-step screening protocols, uncommon aneuploidies, screening for preeclampsia, and open neural tube defects for clinicians interested in fetal medicine. Down syndrome is the most typical genetic condition affecting over 5 million individuals globally. Rapid advances in the medical field make it possible to identify most of these babies before birth. Hence, aneuploidy screening is now offered to pregnant women worldwide. The book aims to help obstetricians and gynecologists diagnose Down syndrome and other aneuploidies in pregnancy, avoid unnecessary testing, and remain safely within medico-legal boundaries. It is also helpful for fetal medicine students. The book helps the readers address challenging clinical scenarios and confusing test results.
Von der Natur inspirierte intelligente Datenverarbeitungstechniken in der Bioinformatik
by Khalid RazaDieses Buch umfasst und beschäftigt sich mit den jüngsten Fortschritten und modernsten Anwendungen von naturinspirierten Computertechniken (NIC) im Bereich der Bioinformatik und der Computerbiologie, die die medizinischen Wissenschaften bei verschiedenen klinischen Anwendungen unterstützen können. Dieser Sammelband befasst sich mit den grundlegenden Anwendungen, dem Umfang und den Zukunftsperspektiven von NIC-Techniken in der Bioinformatik, einschließlich der Erstellung von Genomprofilen, der Klassifizierung von Genexpressionsdaten, der DNA-Berechnung, der System- und Netzwerkbiologie, der Lösung von Komplikationen bei personalisierten Therapien, der antimikrobiellen Resistenz bei bakteriellen Krankheitserregern und der computergestützten Entwicklung von Arzneimitteln, deren Entdeckung und Therapie. Darüber hinaus wird die Rolle von NIC-Techniken bei verschiedenen Krankheiten und Störungen behandelt, einschließlich Krebserkennung und -diagnose, Brustkrebs, Erkennung von Lungenkrankheiten, Krankheits-Biomarkern und Identifizierung potenzieller Therapeutika.
Sleep Apnea Frontiers: Pathophysiology, Diagnosis, and Treatment Strategies (Progress in Sleep Research)
by Ahmed S. BaHammam Mahadevappa HunasikattiThis book delves into the multifaceted world of sleep apnea, presenting the latest advancements, challenges, and perspectives in the field. The book covers various topics, including neuro-stimulator use, positive airway pressure therapies, non-PAP and non-surgical treatments, surgical interventions, diagnosis and management of various sleep apnea phenotypes and comorbidities, and special populations such as pediatric and intensive care unit patients. The book discusses the pathophysiology and mechanisms underlying sleep apnea, examining the role of circulating miRNA as a potential biomarker for diagnosis. It also addresses the adverse health consequences associated with sleep apnea, including cardiovascular disease, diabetes, cancer, and hypertension. Furthermore, the book explores the application of telemedicine and wearable technologies in diagnosing and treating sleep apnea, as well as the impact of external factors such as the COVID-19 pandemic and traffic safety concerns related to sleep deprivation and sleep disorders. The book also highlights the importance of perioperative assessment and management of patients with sleep disorders, the role of REM sleep in sleep disorders, recent advances in sleep during pregnancy and postpartum, and the influence of sleep disturbances on hospitalized and intensive care unit patients. With contributions from experts in the field, this book offers valuable insights into the current state of sleep apnea research and practice, serving as a solid foundation for healthcare professionals, researchers, and students interested in understanding and addressing this prevalent sleep disorder. By providing a comprehensive overview of the field, this book aims to inspire further research and innovation in the diagnosis, treatment, and management of sleep apnea and related sleep disorders.
Ophthalmic Signs in Practice of Medicine
by Amod Gupta Reema Bansal Aman Sharma Arun KapilThe book provides basic knowledge of clinical ophthalmic signs and their application in the clinical practice of medicine. It discusses several intra and extraocular signs that help the ophthalmologists to reach a diagnosis and suggest the presence or absence of an underlying severe sight-threatening or even life-threatening disease, such as diabetes, hypertension, cardiovascular disease, hematological disorders, systemic vasculitis, rheumatological disorders, brain tumors, sarcoidosis, or infectious diseases caused by M. tuberculosis, HIV or herpes viruses. The book is divided into two sections and each chapter is dedicated to one ophthalmic sign providing its pathophysiology, significance, differential diagnosis and clues to systemic disease. Each chapter is profusely illustrated with color and black and white images, and boxes with key messages on differential diagnosis and appropriate laboratory investigations. This book serves as a one-stop resource discussing the significance of individual ophthalmic signs and their context to sensitize the physicians, both the graduates and postgraduates in training, residents and fellows in ophthalmology, family medicine and internal medicine, and practicing physicians.
Proceedings of the Second International Conference of Innovative Textiles and Developed Materials-ITDM’2; 05-06 May 2023; Tunisia: Research Innovations in Smart, Technical and Ecological Textiles
by Saber Ben Abdessalem Mohamed Hamdaoui Ayda Baffoun Adel ElamriThis book includes selected articles from the 2nd International Conference on Innovative Textiles and Developed Materials (ITDM’2) held in Monastir, Tunisia, on May 5 and 6, 2023. The articles present latest scientific concepts and technological advances in innovative and sustainable textile materials and processes worldwide. The conference promotes exchange of ideas and emerging technologies to foster collaboration between academia and industry.
City Responses to Disruptions in 2020: From Lockdowns to Aftermath (Advances in 21st Century Human Settlements)
by Giuseppe T. Cirella Bharat DahiyaThis book presents the integrating of economics and urban geography to create a framework of cooperation around the idea of urban economic stability. It explores these disciplines through the economic lens and creates a collaborative environment for addressing the global challenges caused by the COVID-19 pandemic and future global shocks. Environmental advocates and proponents of economic growth are increasingly at odds—having looked at the economic impact of the decline of the environment as well as the environmental loss that occurs with unchecked growth and urbanization. The outbreak of the COVID-19 pandemic changed the global scene. The world shook in its foundations, as a number of countries’ lockdown affected not only the global economy but also society and the environment. The global community has seen the negative impact of COVID-19 on our economies. There have been steep declines in gross domestic product, job losses have been in the millions, and people have seen their incomes fall. An unplanned shutdown has taken its toll and has been a shock to the economies of the world. Past shocks and how they have impacted urban economies as well as for how long are core to bettering our understanding of present and future urban economic change. The underlying economic factors that make a shock more damaging to certain economies or industries, as well as understanding these vulnerabilities, help entities recover from economic shocks and allow them to better understand how impacts on individual businesses can be implemented. The pandemic revealed the need to adopt a global development approach, taking into consideration four dimensions: global value chains, debt, digitalization, and the environment. Topics related to the causation and lockdown are explored through a number of case studies from around the world.
Resilience vs Pandemics: Innovations in Cities and Neighbourhoods (Urban Sustainability)
by Ali Cheshmehzangi Maycon Sedrez Hang Zhao Tian Li Tim Heath Ayotunde DawoduThe COVID-19 pandemic and other highly transmissible diseases outbreaks have given a new significance to the concept of “resilience”, placing it in the spotlight of built environment-related studies. New directions have emerged from expanding on adaptive planning, urban layouts, urban morphologies, spatial planning, healthy cities, etc. To enhance resilience in the post-pandemic era, various theories, practices, and hypotheses are being formulated by scholars around the world.For this book project, we invite chapter proposals that provide forefront discoveries about the built environment resilience during and after the ongoing pandemic. Historical perspectives of resilience and other highly transmissible diseases are also relevant to understanding the COVID-19 issues. The authors are encouraged to elaborate on critical exploratory, innovative, and cutting-edge research approaches, highlighting the effects of COVID-19 and other highly transmissible diseases in the design, planning, and perception of the built environment. We aim to gather scientific experiences, reviews, analyses, discussions, recommendations, and solutions in the fields of urban planning, urban design, urban management, environmental science, architecture, etc.The book aims to document resilience-related innovations and new perspectives for the built environment, how people’s interactions adapt to new realities, and which mechanisms, tools, and strategies are required for such transformations in the following two scales of the built environments:(1) City/district; research on planning, commuting and mobility, politics, urban configurations, regulations, transmission and prevention, models, top-down processes, innovation processes, etc.(2) Community/neighborhood; research on collaboration, transmission and prevention, isolation and quarantine, social aspects, accessibility to services, technologies, education, policies, and innovative solutions.The book covers a wide range of studies, including physical and non-physical studies, which may refer to the city infrastructure, green/blue spaces, housing, policy-making, health services, social and economic issues, etc. The findings and results contribute to the decision-making of governments, organizations, and institutions, as well as inspire scholars and future research for developing resilience in the post-pandemic era.
Introduction to Quality by Design (QbD): From Theory to Practice
by N. K. Jain Neha BajwaThis book offers a comprehensive exploration of the Quality by Design (QbD) methodology, guiding readers from theory to practical application with accessible examples. It equips readers with both foundational and advanced knowledge, emphasizing the critical parameters necessary for designing pharmaceutical products that meet the highest quality standards. The book goes beyond theory to demonstrate how to effectively implement QbD principles in various aspects of pharmaceutical research and development, including analytical methods, formulation, and packaging processes. Through a step-by-step approach, it prepares researchers in pharmaceutical sciences, as well as professionals in the pharmaceutical and healthcare industries (including suppliers), to successfully integrate QbD into their work.
Wearable Biosensing in Medicine and Healthcare
by Kohji MitsubayashiThis book contains chapters on wearable biomedical sensors and their assistive technologies for promoting behavioral change in medical and health care. Part I reviews several wearable biomedical sensors based on biocompatible materials and nano and micro-electromechanical systems (MEMS) technologies in the medical and dental fields. Part II introduces the latest approaches to wearable biosensing using unique devices for various skin targets such as sweat, interstitial fluid, and transcutaneous gases. Part III presents technologies supporting wearable sensors, including soft and flexible materials, manufacturing methods, skin volatile-marker imaging, and energy harvesting devices.This book is intended for graduate students, academic researchers, and professors that work in medical and healthcare research fields, as well as industry professionals involved in the development of wearable and flexible sensing devices and measurement systems for human bio/chemical sensing, medical monitoring, and healthcare services, and for medical professionals and government officials who are driving behavior change in health care.
Mueller-Matrix Tomography of Biological Tissues and Fluids: Digital Image Processing and Analysis Techniques (SpringerBriefs in Applied Sciences and Technology)
by Zhengbing Hu Yuriy A. Ushenko Iryna V. Soltys Oleksandr V. Dubolazov M. P. Gorsky Oleksandr V. Olar Liliya Yu. TrifonyukThis book presents experimental investigations and digital image processing, highlighting the interaction of polarized radiation with phase-inhomogeneous and optically anisotropic biological layers. The promising and efficient use of vector-parametric description of the formation of polarization-inhomogeneous object fields is noted. Applications of a set of Mueller-matrix polarimetry methods are highlighted. The book includes- structural and logical scheme of multi-parameter (singular, interference and layer-by-layer Stokes-polarimetric), polarization-correlation study of the structure of distributions of the number of singularities, maps of local contrast of interference distributions and layer-by-layer maps of microscopic polarization azimuth and ellipticity; determination of relationships between changes in the magnitude of statistical parameters characterizing polarization-correlation distributions and pathology of prostate tumors.
Association Analysis Techniques and Applications in Bioinformatics
by Qingfeng ChenAdvances in experimental technologies have given rise to tremendous amounts of biology data. This not only offers valuable sources of data to help understand biological evolution and functional mechanisms, but also poses challenges for accurate and effective data analysis. This book offers an essential introduction to the theoretical and practical aspects of association analysis, including data pre-processing, data mining methods/algorithms, and tools that are widely applied for computational biology. It covers significant recent advances in the field, both foundational and application-oriented, helping readers understand the basic principles and emerging techniques used to discover interesting association patterns in diverse and heterogeneous biology data, such as structure-function correlations, and complex networks with gene/protein regulation. The main results and approaches are described in an easy-to-follow way and accompanied by sufficientreferences and suggestions for future research. This carefully edited monograph is intended to provide investigators in the fields of data mining, machine learning, artificial intelligence, and bioinformatics with a profound guide to the role of association analysis in computational biology. It is also very useful as a general source of information on association analysis, and as an overall accompanying course book and self-study material for graduate students and researchers in both computer science and bioinformatics.
Kokumi Substance as an Enhancer of Koku: Biochemistry, Physiology, and Food Science
by Motonaka KurodaThis book provides the basic concepts and latest findings on kokumi substances. It covers not only the topics related to food chemistry, but also the biochemical and physiological mechanisms of the perception of kokumi substances. Food palatability is determined by many factors, including taste, aroma, texture, color, physiological condition, and circumstances. The attribute called “koku” is used in Japan to express delicious foods. The definition of koku attribute was previously proposed to be caused by the sensation of richness, body, lingering (continuity), and mouthfulness in terms of taste, aroma, and texture. Kokumi substance is one of the taste-related koku enhancers and is defined as a substance that enhances complexity, richness (body), and lastingness (continuity), although it has no taste itself at the dose. The topics in this book cover physiological studies, including the receptor mechanism, taste nerve recording, and human brain responses using functional MRI. It also discusses the sensory characteristics of kokumi substances when added to foods and the effect of kokumi substances on the satiety. The intended readers are university students, researchers and technologists in food science, food chemistry, nutritional sciences, taste physiology, and neuroscience. Non-expert readers interested in food palatability and the deliciousness of foods may also find this book useful.
Diagnostic Imaging of Drug Resistant Pulmonary Tuberculosis
by Pu-Xuan Lu Hong-Zhou Lu Yong-Xiang YiTuberculosis is among the top 10 causes of death worldwide.The WHO clearly proposed that drug-resistant tuberculosis is one of the three major challenge in tuberculosis prevention and control .The book consists of detection of drug-resistant TB and its epidemics, laboratory examination for drug-resistant tubercle bacillus, pathogenic mechanism of drug-resistant TB and its diagnosis, differential diagnosis, treatment, prevention and prognosis of drug-resistant pulmonary TB. This book also focuses on the information of classic cases of drug-resistant TB, including mono-drug-resistant (including Rifampicin resistance, etc.), multidrug-resistant, poly-drug-resistant, extensive-drug-resistant (pre-extensive-drug-resistant), drug-resistant bronchial TB, and pediatric drug-resistant, as well as AIDS complicated with drug-resistant TB, and diagnosis and treatment of drug-resistant cervical TB lymphadenitis. The book also provided a comprehensive description and in-depth analysis for each selected case and a systematic explanation for latest cutting-edge issues, such as dynamic changes in images during the treatment of drug-resistant TB as well as the research and application of artificial intelligence in diagnosing drug-resistant TB, to further inspire our readers. This is a useful book to refer to for respiratory physicians, radiologists, and clinicians in preventive medicine, as well as government officials working in health policies.
Extracellular Vesicles: From Bench to Bedside
by Qian Wang Lei ZhengThis book aims to provide a comprehensive and systematic understanding of research on extracellular vesicles (EVs). Extracellular vesicles, including exosomes and microvesicles, are nano-sized lipid bilayer encapsulated membranes carrying proteins, lipids, nucleic acids. They are shed by the majority of the cells into the extracellular milieu and present in many biological fluids (blood, urine, saliva, breast milk, cerebrospinal fluid, follicular fluid, semen, lung lavage, and tears). With numerous research publications in recent years, the study of EVs is the emerging field across plenty of disciplines. Many researches and efforts have shown their biogenesis, multiple roles in physiological and pathophysiological processes, and their potential roles as therapeutic agents. The book is organized by outstanding scientists in EV field from the Chinese Society for Extracellular Vesicle (CSEV). It covers the biological basic research of EVs, especially on technologies and methods, as well as the clinical application of EVs as biomarkers for disease diagnosis and therapy.
Proceedings of the 9th IRC Conference on Science, Engineering, and Technology: IRC-SET 2023; 19-August, Singapore
by Jiqiang Lu Huaqun Guo Ian McLoughlin Eyasu Getahun Chekole Umayal Lakshmanan Weizhi Meng Peng Cheng Wang Nicholas Heng Loong WongThis book highlights the contemporary state of research in multidisciplinary areas of Computer Science, Computer Engineering, Data Science, Electrical and Electronics Engineering, Chemical Engineering, Mechanical Engineering, Physics, Biomedical Sciences, Life Sciences, Medicine, Healthcare, and Business Technology. The accepted submissions to the 9th IRC Conference on Science, Engineering and Technology (IRC-SET 2023) presented on 19 August 2023 are published in this conference proceedings. The papers presented here were shortlisted after extensive rounds of rigorous reviews by a panel of esteemed individuals who are pioneers and experts in their respective domains.
Exosomes Based Drug Delivery Strategies for Brain Disorders
by Neeraj Mishra Sumel Ashique Ashish Garg Vadivalagan Chithravel Krishnan AnandThis book provides a comprehensive overview of the role of exosomes in brain diseases, including stroke, multiple sclerosis, Parkinson's disease, Alzheimer's disease, epilepsy, and depression. It covers the basics of exosome biogenesis, composition, and synthesis, as well as the therapeutic potential of exosomes in brain disorders. The correlation between exosomes and neuroinflammation, the challenges of using exosomes as a novel carrier, and engineered exosomes to deliver therapeutic protein are covered well in this book. Use of radiolabelled exosomes as a diagnostic tool and the toxicity studies of exosomes with potential overcome approaches. It is an essential resource for researchers, clinicians, and healthcare professionals working in the field of exosome research, especially on its applications in brain disorders.
Surgical Management of Pheochromocytoma and Retroperitoneal Paraganglioma
by Jin WenThis book provides readers information on optimal decision on surgical management of pheochromocytoma and retroperitoneal raraganglioma. After overviewing clinical features and diagnosis of pheochromocytoma and retroperitoneal raraganglioma, following chapter presents surgical treatment of adrenal pheochromocytoma, abdominal paraganglioma, paragangliomas in the bladder and scrotum with selected cases. Treatment options and complications from perspective of urologists, endocrinologists, and thoracic surgeons are highlighted to provide a multidisciplinary approach to treatment of patients. This book is suitable for the urologists, endocrinologists and surgeons in oncology, as well as practitioners who are interested in this field.
Errors in Medical Science Investigations
by Hamid SooriThis book introduces all common errors in medical science fields and the ways to control them. Systematic errors could be controlled both during study design and statistical analysis. Some errors have been presented in small segments but not in a comprehensive book. It covers many common errors that usually affect the research proposals, final reports, theses, and scientific presentations in the field of medical sciences as well as the rejection reasons on scientific papers. It will help researchers to control common errors using epidemiological and statistical methods.
Internal Migration and Health in China: Choices, Constraints and Implications
by Yan LiThis book focuses on the multifaceted reality of social and health constraints and health services access among migrants in China, by originally exploring the social strata, social networks, and the understanding of health and health services among migrants. Furthermore, this book investigates the health constraints and health services access of rural-urban migrants in the absence of equal social protection by the government. It argues that the main obstacles to access health services are not only the shortage of financial resources among rural-urban migrants, but also lie in the institutional blindness regarding health security provision, rural-urban dualism and the household registration system in China. The book highlights the key function that social networks play in health and health services access among migrants in China, which has rarely been discussed in previous studies. And it also discusses the understanding of health among migrants, and further analyses that although many migrants have not formed proper understanding of the connotation of health and have limited knowledge of health, prime responsibility should not be put on the migrants because their poor understanding of health mainly results from their rural perspective while health and health services access depend on the social-economic environment in which they live and work.This book would be of interest to people in migration studies, social exclusion and social welfare studies and to people interested in rural-urban migration and health in China.
A History of Western Pharmacy in China
by Patrick Chiu“This book represents an important contribution to the field as it is the first to provide a detailed account of the interaction between Chinese and western medicine from a pharmacy perspective over a period of two millennia with an emphasis on the modern period from 1800-1949. None of the existing historiography on the relationship between TCM and western medicine has so far explored pharmaceutical aspects in detail. This book therefore fills an important gap in the literature and is likely to become a key resource for further study. It will be of interest to a wide audience, including pharmaceutical, imperial, and business historians, and should be essential reading for pharmacy students. But it will also be of interest to a general readership curious about the history of pharmacy in China and of western influences on Chinese medicine. Stuart Anderson, BSc, MA, PhD, FRPharmS Editor-in-Chef, Pharmaceutical Historian, Emeritus Professor of Pharmacy History, London School of Hygiene & Tropical Medicine “Readers of this book, to Chiu’s credit, will be exposed to the nuanced cultural, medico-scientific, and business interactions that shaped Western pharmacy in China. Chiu puts a spotlight on the various materials, techniques, and processes of drug formulation and mass manufacture – and he rightly illustrates how pharmacy was substantiated as big business and mass manufacture. In analyses that incorporate materia medica and so-called dangerous drugs, such as opium, Chiu also articulates the complicated entangled histories of the movement, circulation, and translation of both pharmacy knowledge and goods. Yet, he appropriately acknowledges and evaluates non-Western epistemologies and practices that intermingled with Western ideas to create a novel type of pharmacy and pharmaceutical industry in China. Lucas Richert, PhD Professor & George Urdang Chair in Pharmacy History, UW-Madison Executive Director, American Institute of the History of Pharmacy”Patrick Chiu's book, A History of Western Pharmacy in China, effectively presents an unbiased perspective when discussing the contributions of expatriate pharmacy academics towards the development of China's pharmaceutical profession and the modern drug industry in the first half of the twentieth century. Chiu's impartial approach and well-researched content make it a recommended resource for understanding the historical development of pharmacy in China. Kazushige Morimoto Ph.D. D.Min, Education System - Qualified Pharmacist, President, The Japanese Society for the History of Pharmacy
Emergent Converging Technologies and Biomedical Systems: Select Proceedings of the 3rd International Conference, ETBS 2023 (Lecture Notes in Electrical Engineering #1116)
by Shruti Jain Nikhil Marriwala Pushpendra Singh C. C. Tripathi Dinesh KumarThe book contains proceedings of the International Conference on Emergent Converging Technologies and Biomedical Systems ETBS 2023. It includes papers on wireless multimedia networks, green wireless networks, electric vehicles, biomedical signal processing, and instrumentation, wearable sensors for health care monitoring, biomedical imaging, and bio-materials, modeling, and simulation in medicine biomedical, and health informatics. The book serves as a useful guide for educators, researchers, and developers working in the areas of signal processing, imaging, computing, instrumentation, artificial intelligence, and their related applications. This book also provides support and aid to the researchers involved in designing the latest advancements in healthcare technologies.
Case-based Approach to Common Neurological Disorders
by Krishna Kumar Oli Gentle Sunder Shrestha Rajeev Ojha Pramod Kumar Pal Sanjay Pandey Bibhukalyani DasThis book primarily aims to assists doctors from non-neuroscience background to acquire knowledge about common neurological disorders encountered in a resource-constrained setup in a case-based and practical approach. The book elucidates the value of proper and systematic approach to the patient, how proper history taking and clinical evaluation, followed by appropriate investigations can narrow down the differential diagnoses and help proper and timely management of the patients.The book covers most of the common neurological disorders and scenarios encountered in clinical practice and will benefit clinicians facing difficult cases, particularly those involving fundamental research and diagnostic methods. This book is useful for physicians working in internal medicine, physicians handling neurology cases in resource-constrained facilities, and fellows in neurology. The contents of this book support and practically enhance the knowledge acquiredfrom other text books.
ESKAPE Pathogens: Detection, Mechanisms and Treatment Strategies
by Siddhardha Busi Ram PrasadThis book explores the medical importance of Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. (ESKAPE) pathogens, and the challenges posed by antibiotic resistance. It covers the antibiotic resistance profile and detection of ESKAPE pathogens, as well as the mechanistic understanding of antibiotic resistance in these pathogens. The book discusses standard microbiological techniques, including staining, morphological and cultural characteristics, biochemical properties, and serotyping, as well as nucleic acid amplification and molecular diagnostic techniques for the detection of ESKAPE pathogens. In addition, the book explores biochemical, molecular, and computational techniques for the determination of virulence factors of ESKAPE pathogens. It also examines the synthesis, structure, function, and inhibitors of virulence factors and biofilm componentsin these pathogens. The book explores various strategies for combating ESKAPE pathogens, including antibiotic adjuvants and their synergistic activity, phytochemicals as potential antibacterial agents, photodynamic therapy, antimicrobial peptides and antibacterial antibodies, antimicrobial activity of Nanomaterials and Nanocomposites, and bacteriophage therapy. Finally, the book discusses in silico and computational approaches for the inhibition of ESKAPE pathogens. This comprehensive book is of interest to researchers, students, and healthcare professionals interested in the diagnosis, prevention, and treatment of ESKAPE pathogens.
Gut Microbiome and Brain Ageing: Brain Aging
by Surajit Pathak Antara BanerjeeThis book, Gut microbiome and Brain Ageing, deals with the mechanisms and phenomenon that relates gut microbiome and aging of the brain. This book will bring forth the connection between good gut and brain aging and includes some cutting edge research topics dealing with gut physiology and its importance as future therapeutic option in neurological disorders. The gut microbiome's impact on neuronal function, mediated by neurotransmitters, vitamins, and neuroactive microbial metabolites, is an exciting area of investigation that this book thoroughly explores. It also covers the pivotal role of the gut microbiome in the etiology of various neurodegenerative disorders such as Alzheimer’s disease (AD), Parkinson’s disease (PD), depression, or multiple sclerosis (MS). It also explores the expanding understanding of the importance of the early-life gut microbiota and its implications for long-term health consequences. This book primarily addresses researchers, clinicians, and doctoral andgraduate students working in biomedicine, neurobiology, nutrition, microbiology, and translational medicine streams.