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Hematopoietic Stem Cells: Keystone of Tissue Development and Regenerative Medicine (Advances in Experimental Medicine and Biology #1442)
by Meng Zhao Pengxu QianThis book renders a comprehensive understanding of hematopoietic stem cells (HSCs) from their embryonic development through adult maintenance to aging, in the studies conducted in zebrafish and mammals. Hematopoiesis provides a paradigm for understanding the development, maintenance, regeneration, aging and malignant transformation of mammalian organs. Sitting at the apex of the hematopoiesis hierarchy tree, HSCs orchestrate their proliferation, self-renewal, and differentiation to produce all the blood cell lineages throughout life, which represents the best example for somatic stem cell studies. In this book, key regulatory mechanisms for HSC self-renewal and differentiation are overviewed in an array of fields including epigenetics, metabolism and microenvironment regulation. It also highlights the HSC heterogeneity and clonal dynamics from the recent advanced single-cell technologies. This book elaborates on the research history of HSC studies and reveals how the insights from HSC studies shed light on their clinic application. It presents great value from the bench to the clinic.
Beamforming in Medical Ultrasound Imaging (Springer Tracts in Electrical and Electronics Engineering)
by Babak Mohammadzadeh Asl Roya ParidarThis book deals with the concept of medical ultrasound imaging and discusses array signal processing in ultrasound. Signal processing using different beamforming techniques in order to achieve a desirable reconstructed image and, consequently, obtain useful information about the imaging medium is the main focus of this book. In this regard, the principles of image reconstruction techniques in ultrasound imaging are fully described, and the required processing steps are completely expanded and analyzed in detail. Simulation results to compare the performance of different beamformers are also included in this book to visualize their differences to the reader. Other advanced techniques in the field of medical ultrasound data processing, as well as their corresponding recent achievements, are also presented in this book. Simply put, in this book, processing of medical ultrasound data from different aspects and acquiring information from them in different manners are covered and organized in different chapters. Before going through the detailed explanation in each chapter, it gives the reader an overview of the considered issue and focuses his\her mind on the challenge ahead. The contents of the book are also presented in such a way that they are easy for the reader to understand. This book is recommended for researchers who study medical ultrasound data processing.
Advances of Multisensory Integration in the Brain (Advances in Experimental Medicine and Biology #1437)
by Yong Gu Adam ZaidelThis book presents the latest research on multisensory brain function. Namely, the mechanisms by which the brain processes and integrates information from multiple sensory modalities. Its contents cover a broad range of topics, including optimal integration, cross-modal interactions, calibration, and causal inference – with an emphasis on their neuronal underpinnings. By bringing together efforts from different laboratories around the world we aim to collaboratively shed light on these fundamental brain processes, that underlie perception, cognition, and behavior in a complex multisensory world, and to spur innovation of brain-inspired technologies
Nanomedicine in Treatment of Diseases (Learning Materials in Biosciences)
by Bushra Akhtar Faqir Muhammad Ali SharifNanomedicine biotechnology is applied to and used to study drug development, working mechanisms, diagnosis, and therapies. This textbook particularly written for biomedical applications of nanomedicine covers the whole range of disease treatments related to nanomedicine. This book serves the purpose of highlighting the current advancements of nanomedicines-based regimens which may be employed in disease treatment while it also contains the fundamental knowledge for biomedical researchers from all levels. Each chapter starts with an introduction/theory into the specified approaches for various disease states followed by detailed discussions for a comprehensive understanding. This book best suits advanced level students, but also provides an excellent updated material for researchers and healthcare workers related to nanomedicine and diseases treatment.
Adaptation under Stressful Environments through Biological Adjustments and Interventions
by Rajkumar Tulsawani Divya VohoraThe book delves into the intricate interplay of stress and adaptive responses, and their multifaceted dynamics influenced by stress type, exposure duration, genetic factors, and lifestyle elements. It unveils the complexity of stress management, unveiling how adaptive strategies evolve in response to stressors. By harnessing scientific breakthroughs in stress response comprehension, the book navigates the path to effective stress mitigation. Through avenues such as pharmacological interventions, dietary adjustments, psychological enhancement, and more, the book advocates for achieving adaptive resilience—a state where the system effectively copes with stress. The text encapsulates an array of stressors, including extreme stress, oxidative stress, and genotoxic stress, dissecting their impact on systemic equilibrium and health. The book's focal point rests on adaptive mechanisms that vary with stressor types, while also spotlighting how these mechanisms can be calibrated through pharmacological and alternative means. This is an invaluable resource for understanding, mitigating, and harnessing the power of adaptation in the face of stress-induced challenges.
Role of Herbal Medicines: Management of Lifestyle Diseases
by Amal Kumar Dhara Subhash C. MandalEmergence of lifestyle diseases, e.g., type II diabetes, cancers, obesity, cardiovascular disorders, liver cirrhosis, etc., are exponentially increasing day by day. Modern drifts toward the utilization of herbal medicines in different healthcare aspects necessitate (demand) the replacement of synthetic molecules with phytoconstituents because of their biocompatibility, biodegradability, economic extraction process, and ready availability from the natural source. This book provides a thorough insight into the comprehensive and up-to-date trends of phytomedicines in the management of lifestyle diseases and its mechanisms, modern methods of extraction and purification of phytoconstituents, and chemical characterization as well as standardization of phytoconstituents using modern equipments.
Mercury Toxicity: Challenges and Solutions (Environmental Science and Engineering)
by Nitish KumarThis book presents mercury toxicity with respect to remediation and health issues. It covers sources of mercury contamination, its impact on human health, and prospective remediation by both bioremediation and phytoremediation with the application of recent advanced techniques such as genetic engineering and nanotechnology.Both anthropogenic activities and natural processes cause the release of mercury into different spheres of the environment resulting in severe adverse impacts. Increased anthropogenic discharge of mercury leads to disturbance in its natural biogeochemical cycle, which results in unenviable diseases and hazardous health effects. Mercury pollution is responsible for causing neurobehavioral, kidney, heart, gastrointestinal, liver, and other diseases. Many published works about the impact of mercury on health are also available worldwide; however, there is no complete understanding available on toxicological studies of mercury that covers the broader spectrum of findings ranging from sources of exposure to mercury toxicity to its remediation strategies.This book brings together a diverse group of environmental science, sustainability, and health researchers to address the challenges posed by global mass poisoning caused by mercury contamination. The book also proposes solutions to contamination through multi-disciplinary approaches.The book contains three sections. The first part describes the different sources and distribution of mercury in soil and plant ecosystems. The second part explains the health risks linked to mercury toxicity. The third part addresses sustainable mercury toxicity mitigation strategies and the potential applications of recent technology in providing solutions. This book is a valuable resource to students, academics, researchers, and environmental professionals working in the field of mercury contamination.
Curcumin and Neurodegenerative Diseases: From Traditional to Translational Medicines
by Mahendra Rai Chistiane M. FeitosaThis book explores the potential benefits of turmeric, and specifically curcumin, in the treatment and prevention of neurodegenerative diseases. The book covers various aspects of turmeric, including its traditional use in Ayurveda and Chinese medicine, secondary metabolites, curcuminoids, and sesquiterpenoids found in turmeric, as well as the use of nano curcumin in neurodegenerative diseases. It discusses the different ways in which turmeric can be used to treat neurodegenerative diseases, including as a therapy for brain diseases, curcumin-induced neuroprotection in cerebral ischemia, and neural stem cell therapy in combination with curcumin. It also discusses the role of nano curcumin in neurodegenerative diseases, including its potential use in the treatment of Alzheimer's disease. The book provides the scientific evidence behind the use of turmeric and its compounds in the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Overall, this book is an invaluable resource for researchers and healthcare professionals interested in exploring the potential benefits of turmeric and curcumin in the treatment and prevention of neurodegenerative diseases.
Urine Formed Elements
by Lei Zheng Lizhi Yan Shimin ZhangThis book introduces the various urinary formed elements comprehensively, mainly including exfoliated cells, crystals and casts. Since the urinary formed elements are affected by various factors and their morphology may change, these components are identified by combining a variety of staining techniques. Various kinds of clinical classic cases are introduced, which are illustrated by richness high-definition colour pictures.
Down Syndrome Screening: A Practical Guide
by Abhijit KamatThe book elucidates a practical method for prenatal screening and detecting Down syndrome in a simple and easy-to-understand language. It provides thorough knowledge on the subject, and each chapter covers a specific topic, making this book an essential quick-reference guide for every antenatal clinic. The book contains chapters on maternal serum screening, noninvasive prenatal testing (NIPT), invasive testing with amniocentesis and CVS, and screening in twins. It also includes advanced chapters on multi-step screening protocols, uncommon aneuploidies, screening for preeclampsia, and open neural tube defects for clinicians interested in fetal medicine. Down syndrome is the most typical genetic condition affecting over 5 million individuals globally. Rapid advances in the medical field make it possible to identify most of these babies before birth. Hence, aneuploidy screening is now offered to pregnant women worldwide. The book aims to help obstetricians and gynecologists diagnose Down syndrome and other aneuploidies in pregnancy, avoid unnecessary testing, and remain safely within medico-legal boundaries. It is also helpful for fetal medicine students. The book helps the readers address challenging clinical scenarios and confusing test results.
Von der Natur inspirierte intelligente Datenverarbeitungstechniken in der Bioinformatik
by Khalid RazaDieses Buch umfasst und beschäftigt sich mit den jüngsten Fortschritten und modernsten Anwendungen von naturinspirierten Computertechniken (NIC) im Bereich der Bioinformatik und der Computerbiologie, die die medizinischen Wissenschaften bei verschiedenen klinischen Anwendungen unterstützen können. Dieser Sammelband befasst sich mit den grundlegenden Anwendungen, dem Umfang und den Zukunftsperspektiven von NIC-Techniken in der Bioinformatik, einschließlich der Erstellung von Genomprofilen, der Klassifizierung von Genexpressionsdaten, der DNA-Berechnung, der System- und Netzwerkbiologie, der Lösung von Komplikationen bei personalisierten Therapien, der antimikrobiellen Resistenz bei bakteriellen Krankheitserregern und der computergestützten Entwicklung von Arzneimitteln, deren Entdeckung und Therapie. Darüber hinaus wird die Rolle von NIC-Techniken bei verschiedenen Krankheiten und Störungen behandelt, einschließlich Krebserkennung und -diagnose, Brustkrebs, Erkennung von Lungenkrankheiten, Krankheits-Biomarkern und Identifizierung potenzieller Therapeutika.
Sleep Apnea Frontiers: Pathophysiology, Diagnosis, and Treatment Strategies (Progress in Sleep Research)
by Ahmed S. BaHammam Mahadevappa HunasikattiThis book delves into the multifaceted world of sleep apnea, presenting the latest advancements, challenges, and perspectives in the field. The book covers various topics, including neuro-stimulator use, positive airway pressure therapies, non-PAP and non-surgical treatments, surgical interventions, diagnosis and management of various sleep apnea phenotypes and comorbidities, and special populations such as pediatric and intensive care unit patients. The book discusses the pathophysiology and mechanisms underlying sleep apnea, examining the role of circulating miRNA as a potential biomarker for diagnosis. It also addresses the adverse health consequences associated with sleep apnea, including cardiovascular disease, diabetes, cancer, and hypertension. Furthermore, the book explores the application of telemedicine and wearable technologies in diagnosing and treating sleep apnea, as well as the impact of external factors such as the COVID-19 pandemic and traffic safety concerns related to sleep deprivation and sleep disorders. The book also highlights the importance of perioperative assessment and management of patients with sleep disorders, the role of REM sleep in sleep disorders, recent advances in sleep during pregnancy and postpartum, and the influence of sleep disturbances on hospitalized and intensive care unit patients. With contributions from experts in the field, this book offers valuable insights into the current state of sleep apnea research and practice, serving as a solid foundation for healthcare professionals, researchers, and students interested in understanding and addressing this prevalent sleep disorder. By providing a comprehensive overview of the field, this book aims to inspire further research and innovation in the diagnosis, treatment, and management of sleep apnea and related sleep disorders.
Ophthalmic Signs in Practice of Medicine
by Amod Gupta Reema Bansal Aman Sharma Arun KapilThe book provides basic knowledge of clinical ophthalmic signs and their application in the clinical practice of medicine. It discusses several intra and extraocular signs that help the ophthalmologists to reach a diagnosis and suggest the presence or absence of an underlying severe sight-threatening or even life-threatening disease, such as diabetes, hypertension, cardiovascular disease, hematological disorders, systemic vasculitis, rheumatological disorders, brain tumors, sarcoidosis, or infectious diseases caused by M. tuberculosis, HIV or herpes viruses. The book is divided into two sections and each chapter is dedicated to one ophthalmic sign providing its pathophysiology, significance, differential diagnosis and clues to systemic disease. Each chapter is profusely illustrated with color and black and white images, and boxes with key messages on differential diagnosis and appropriate laboratory investigations. This book serves as a one-stop resource discussing the significance of individual ophthalmic signs and their context to sensitize the physicians, both the graduates and postgraduates in training, residents and fellows in ophthalmology, family medicine and internal medicine, and practicing physicians.
Proceedings of the Second International Conference of Innovative Textiles and Developed Materials-ITDM’2; 05-06 May 2023; Tunisia: Research Innovations in Smart, Technical and Ecological Textiles
by Saber Ben Abdessalem Mohamed Hamdaoui Ayda Baffoun Adel ElamriThis book includes selected articles from the 2nd International Conference on Innovative Textiles and Developed Materials (ITDM’2) held in Monastir, Tunisia, on May 5 and 6, 2023. The articles present latest scientific concepts and technological advances in innovative and sustainable textile materials and processes worldwide. The conference promotes exchange of ideas and emerging technologies to foster collaboration between academia and industry.
City Responses to Disruptions in 2020: From Lockdowns to Aftermath (Advances in 21st Century Human Settlements)
by Giuseppe T. Cirella Bharat DahiyaThis book presents the integrating of economics and urban geography to create a framework of cooperation around the idea of urban economic stability. It explores these disciplines through the economic lens and creates a collaborative environment for addressing the global challenges caused by the COVID-19 pandemic and future global shocks. Environmental advocates and proponents of economic growth are increasingly at odds—having looked at the economic impact of the decline of the environment as well as the environmental loss that occurs with unchecked growth and urbanization. The outbreak of the COVID-19 pandemic changed the global scene. The world shook in its foundations, as a number of countries’ lockdown affected not only the global economy but also society and the environment. The global community has seen the negative impact of COVID-19 on our economies. There have been steep declines in gross domestic product, job losses have been in the millions, and people have seen their incomes fall. An unplanned shutdown has taken its toll and has been a shock to the economies of the world. Past shocks and how they have impacted urban economies as well as for how long are core to bettering our understanding of present and future urban economic change. The underlying economic factors that make a shock more damaging to certain economies or industries, as well as understanding these vulnerabilities, help entities recover from economic shocks and allow them to better understand how impacts on individual businesses can be implemented. The pandemic revealed the need to adopt a global development approach, taking into consideration four dimensions: global value chains, debt, digitalization, and the environment. Topics related to the causation and lockdown are explored through a number of case studies from around the world.
Resilience vs Pandemics: Innovations in Cities and Neighbourhoods (Urban Sustainability)
by Ali Cheshmehzangi Maycon Sedrez Hang Zhao Tian Li Tim Heath Ayotunde DawoduThe COVID-19 pandemic and other highly transmissible diseases outbreaks have given a new significance to the concept of “resilience”, placing it in the spotlight of built environment-related studies. New directions have emerged from expanding on adaptive planning, urban layouts, urban morphologies, spatial planning, healthy cities, etc. To enhance resilience in the post-pandemic era, various theories, practices, and hypotheses are being formulated by scholars around the world.For this book project, we invite chapter proposals that provide forefront discoveries about the built environment resilience during and after the ongoing pandemic. Historical perspectives of resilience and other highly transmissible diseases are also relevant to understanding the COVID-19 issues. The authors are encouraged to elaborate on critical exploratory, innovative, and cutting-edge research approaches, highlighting the effects of COVID-19 and other highly transmissible diseases in the design, planning, and perception of the built environment. We aim to gather scientific experiences, reviews, analyses, discussions, recommendations, and solutions in the fields of urban planning, urban design, urban management, environmental science, architecture, etc.The book aims to document resilience-related innovations and new perspectives for the built environment, how people’s interactions adapt to new realities, and which mechanisms, tools, and strategies are required for such transformations in the following two scales of the built environments:(1) City/district; research on planning, commuting and mobility, politics, urban configurations, regulations, transmission and prevention, models, top-down processes, innovation processes, etc.(2) Community/neighborhood; research on collaboration, transmission and prevention, isolation and quarantine, social aspects, accessibility to services, technologies, education, policies, and innovative solutions.The book covers a wide range of studies, including physical and non-physical studies, which may refer to the city infrastructure, green/blue spaces, housing, policy-making, health services, social and economic issues, etc. The findings and results contribute to the decision-making of governments, organizations, and institutions, as well as inspire scholars and future research for developing resilience in the post-pandemic era.
Introduction to Quality by Design (QbD): From Theory to Practice
by N. K. Jain Neha BajwaThis book offers a comprehensive exploration of the Quality by Design (QbD) methodology, guiding readers from theory to practical application with accessible examples. It equips readers with both foundational and advanced knowledge, emphasizing the critical parameters necessary for designing pharmaceutical products that meet the highest quality standards. The book goes beyond theory to demonstrate how to effectively implement QbD principles in various aspects of pharmaceutical research and development, including analytical methods, formulation, and packaging processes. Through a step-by-step approach, it prepares researchers in pharmaceutical sciences, as well as professionals in the pharmaceutical and healthcare industries (including suppliers), to successfully integrate QbD into their work.
Wearable Biosensing in Medicine and Healthcare
by Kohji MitsubayashiThis book contains chapters on wearable biomedical sensors and their assistive technologies for promoting behavioral change in medical and health care. Part I reviews several wearable biomedical sensors based on biocompatible materials and nano and micro-electromechanical systems (MEMS) technologies in the medical and dental fields. Part II introduces the latest approaches to wearable biosensing using unique devices for various skin targets such as sweat, interstitial fluid, and transcutaneous gases. Part III presents technologies supporting wearable sensors, including soft and flexible materials, manufacturing methods, skin volatile-marker imaging, and energy harvesting devices.This book is intended for graduate students, academic researchers, and professors that work in medical and healthcare research fields, as well as industry professionals involved in the development of wearable and flexible sensing devices and measurement systems for human bio/chemical sensing, medical monitoring, and healthcare services, and for medical professionals and government officials who are driving behavior change in health care.
Mueller-Matrix Tomography of Biological Tissues and Fluids: Digital Image Processing and Analysis Techniques (SpringerBriefs in Applied Sciences and Technology)
by Zhengbing Hu Yuriy A. Ushenko Iryna V. Soltys Oleksandr V. Dubolazov M. P. Gorsky Oleksandr V. Olar Liliya Yu. TrifonyukThis book presents experimental investigations and digital image processing, highlighting the interaction of polarized radiation with phase-inhomogeneous and optically anisotropic biological layers. The promising and efficient use of vector-parametric description of the formation of polarization-inhomogeneous object fields is noted. Applications of a set of Mueller-matrix polarimetry methods are highlighted. The book includes- structural and logical scheme of multi-parameter (singular, interference and layer-by-layer Stokes-polarimetric), polarization-correlation study of the structure of distributions of the number of singularities, maps of local contrast of interference distributions and layer-by-layer maps of microscopic polarization azimuth and ellipticity; determination of relationships between changes in the magnitude of statistical parameters characterizing polarization-correlation distributions and pathology of prostate tumors.
Association Analysis Techniques and Applications in Bioinformatics
by Qingfeng ChenAdvances in experimental technologies have given rise to tremendous amounts of biology data. This not only offers valuable sources of data to help understand biological evolution and functional mechanisms, but also poses challenges for accurate and effective data analysis. This book offers an essential introduction to the theoretical and practical aspects of association analysis, including data pre-processing, data mining methods/algorithms, and tools that are widely applied for computational biology. It covers significant recent advances in the field, both foundational and application-oriented, helping readers understand the basic principles and emerging techniques used to discover interesting association patterns in diverse and heterogeneous biology data, such as structure-function correlations, and complex networks with gene/protein regulation. The main results and approaches are described in an easy-to-follow way and accompanied by sufficientreferences and suggestions for future research. This carefully edited monograph is intended to provide investigators in the fields of data mining, machine learning, artificial intelligence, and bioinformatics with a profound guide to the role of association analysis in computational biology. It is also very useful as a general source of information on association analysis, and as an overall accompanying course book and self-study material for graduate students and researchers in both computer science and bioinformatics.
Kokumi Substance as an Enhancer of Koku: Biochemistry, Physiology, and Food Science
by Motonaka KurodaThis book provides the basic concepts and latest findings on kokumi substances. It covers not only the topics related to food chemistry, but also the biochemical and physiological mechanisms of the perception of kokumi substances. Food palatability is determined by many factors, including taste, aroma, texture, color, physiological condition, and circumstances. The attribute called “koku” is used in Japan to express delicious foods. The definition of koku attribute was previously proposed to be caused by the sensation of richness, body, lingering (continuity), and mouthfulness in terms of taste, aroma, and texture. Kokumi substance is one of the taste-related koku enhancers and is defined as a substance that enhances complexity, richness (body), and lastingness (continuity), although it has no taste itself at the dose. The topics in this book cover physiological studies, including the receptor mechanism, taste nerve recording, and human brain responses using functional MRI. It also discusses the sensory characteristics of kokumi substances when added to foods and the effect of kokumi substances on the satiety. The intended readers are university students, researchers and technologists in food science, food chemistry, nutritional sciences, taste physiology, and neuroscience. Non-expert readers interested in food palatability and the deliciousness of foods may also find this book useful.
Diagnostic Imaging of Drug Resistant Pulmonary Tuberculosis
by Pu-Xuan Lu Hong-Zhou Lu Yong-Xiang YiTuberculosis is among the top 10 causes of death worldwide.The WHO clearly proposed that drug-resistant tuberculosis is one of the three major challenge in tuberculosis prevention and control .The book consists of detection of drug-resistant TB and its epidemics, laboratory examination for drug-resistant tubercle bacillus, pathogenic mechanism of drug-resistant TB and its diagnosis, differential diagnosis, treatment, prevention and prognosis of drug-resistant pulmonary TB. This book also focuses on the information of classic cases of drug-resistant TB, including mono-drug-resistant (including Rifampicin resistance, etc.), multidrug-resistant, poly-drug-resistant, extensive-drug-resistant (pre-extensive-drug-resistant), drug-resistant bronchial TB, and pediatric drug-resistant, as well as AIDS complicated with drug-resistant TB, and diagnosis and treatment of drug-resistant cervical TB lymphadenitis. The book also provided a comprehensive description and in-depth analysis for each selected case and a systematic explanation for latest cutting-edge issues, such as dynamic changes in images during the treatment of drug-resistant TB as well as the research and application of artificial intelligence in diagnosing drug-resistant TB, to further inspire our readers. This is a useful book to refer to for respiratory physicians, radiologists, and clinicians in preventive medicine, as well as government officials working in health policies.
Extracellular Vesicles: From Bench to Bedside
by Qian Wang Lei ZhengThis book aims to provide a comprehensive and systematic understanding of research on extracellular vesicles (EVs). Extracellular vesicles, including exosomes and microvesicles, are nano-sized lipid bilayer encapsulated membranes carrying proteins, lipids, nucleic acids. They are shed by the majority of the cells into the extracellular milieu and present in many biological fluids (blood, urine, saliva, breast milk, cerebrospinal fluid, follicular fluid, semen, lung lavage, and tears). With numerous research publications in recent years, the study of EVs is the emerging field across plenty of disciplines. Many researches and efforts have shown their biogenesis, multiple roles in physiological and pathophysiological processes, and their potential roles as therapeutic agents. The book is organized by outstanding scientists in EV field from the Chinese Society for Extracellular Vesicle (CSEV). It covers the biological basic research of EVs, especially on technologies and methods, as well as the clinical application of EVs as biomarkers for disease diagnosis and therapy.
Proceedings of the 9th IRC Conference on Science, Engineering, and Technology: IRC-SET 2023; 19-August, Singapore
by Jiqiang Lu Huaqun Guo Ian McLoughlin Eyasu Getahun Chekole Umayal Lakshmanan Weizhi Meng Peng Cheng Wang Nicholas Heng Loong WongThis book highlights the contemporary state of research in multidisciplinary areas of Computer Science, Computer Engineering, Data Science, Electrical and Electronics Engineering, Chemical Engineering, Mechanical Engineering, Physics, Biomedical Sciences, Life Sciences, Medicine, Healthcare, and Business Technology. The accepted submissions to the 9th IRC Conference on Science, Engineering and Technology (IRC-SET 2023) presented on 19 August 2023 are published in this conference proceedings. The papers presented here were shortlisted after extensive rounds of rigorous reviews by a panel of esteemed individuals who are pioneers and experts in their respective domains.
Exosomes Based Drug Delivery Strategies for Brain Disorders
by Neeraj Mishra Sumel Ashique Ashish Garg Vadivalagan Chithravel Krishnan AnandThis book provides a comprehensive overview of the role of exosomes in brain diseases, including stroke, multiple sclerosis, Parkinson's disease, Alzheimer's disease, epilepsy, and depression. It covers the basics of exosome biogenesis, composition, and synthesis, as well as the therapeutic potential of exosomes in brain disorders. The correlation between exosomes and neuroinflammation, the challenges of using exosomes as a novel carrier, and engineered exosomes to deliver therapeutic protein are covered well in this book. Use of radiolabelled exosomes as a diagnostic tool and the toxicity studies of exosomes with potential overcome approaches. It is an essential resource for researchers, clinicians, and healthcare professionals working in the field of exosome research, especially on its applications in brain disorders.