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Reaching Down the Rabbit Hole: A Renowned Neurologist Explains the Mystery and Drama of Brain Disease

by Allan H. Ropper Brian David Burrell

"Tell the doctor where it hurts." It sounds simple enough, unless the problem affects the very organ that produces awareness and generates speech. What is it like to try to heal the body when the mind is under attack? In this book, Reaching Down the Rabiit Hole, Dr. Allan H. Ropper and Brian David Burrell take the reader behind the scenes at Harvard Medical School's neurology unit to show how a seasoned diagnostician faces down bizarre, life-altering afflictions. Like Alice in Wonderland, Dr. Ropper inhabits a world where absurdities abound:• A figure skater whose body has become a ticking time-bomb • A salesman who drives around and around a traffic rotary, unable to get off • A college quarterback who can't stop calling the same play • A child molester who, after falling on the ice, is left with a brain that is very much dead inside a body that is very much alive • A mother of two young girls, diagnosed with ALS, who has to decide whether a life locked inside her own head is worth livingHow does one begin to treat such cases, to counsel people whose lives may be changed forever? How does one train the next generation of clinicians to deal with the moral and medical aspects of brain disease? Dr. Ropper and his colleague answer these questions by taking the reader into a rarified world where lives and minds hang in the balance.

The First Family: A Novel

by Michael Palmer Daniel Palmer

The President’s teenaged son is threatened by a potentially fatal illness that is rooted in dark secrets from a long-buried past. President Geoffrey Hilliard and his family live in the ever-present glare of the political limelight, with relentless scrutiny of their daily lives. The White House is not an easy place to grow up, so when the President’s son Cam, a sixteen-year-old chess champion, experiences extreme fatigue, moodiness, and an uncharacteristic violent outburst, doctors are quick to dismiss his troubles as teen angst. But Secret Service agent Karen Ray, whose job is to guard the president's family with her life, is convinced Cam’s issues are serious – serious enough to summon her physician ex-husband for a second opinion. Dr. Lee Blackwood’s concerns are dismissed by the president's team – until Cam gets sicker. Lee must make a diagnosis from a puzzling array of symptoms he's never seen before. His only clue is a patient named Susie Banks, a young musical prodigy who seems to be suffering from the same baffling condition as Cam. Hospitalized after an attempt on her life by a determined killer, Susie’s jeopardy escalates as Cam’s condition takes on a terrifying new dimension.Is someone trying to murder the President’s son? As Lee and Karen race for a cure to Cam’s mysterious and deadly disease, they begin to uncover betrayals that breach the highest levels of national security.Returning to the same Washington, DC setting of The First Patient, which former President Bill Clinton said “captured the intense atmosphere of the White House,” The First Family is a riveting new medical drama from acclaimed novelist Daniel Palmer, in the tradition of his late father, New York Times bestselling novelist Michael Palmer.Praise for The First Family: "Terrifying and all too plausible—Daniel Palmer continues his father's tradition of delivering authentic and high-velocity medical suspense. The combination of medical chills and high-level Washington make The First Family irresistible.” —Joseph Finder, New York Times bestselling author of Paranoia and The Switch"Palmer's The First Family gives you likable characters to root for, a top-notch villain, and enough excitement to make your hair curl. Have fun with this thriller." —Catherine Coulter, author of The Devil's Triangle“Double the trouble, twice the action, and quadruple the enjoyment, this is a high-octane game changer.” —Steve Berry, New York Times bestselling author of The Bishop's Pawn and The Lost Order“High-stakes and intelligent, The First Family is everything you want in a medical thriller. Chilling!”—Robert Dugoni #1 Amazon, Wall Street Journal and New York Times bestselling author of My Sisters Grave"The First Family is adrenaline-fueled entertainment that twists, turns, surprises and satisfies!” -John Lescroart, New York Times bestselling author "A Palmer novel transports you into the complex world of medical-legal-social ethics.The First Family doesn't disappoint, wrestling with the murky questions of what we can do versus what we should do. Gripping.” —Kathy Reichs, New York Times bestselling author and creator of Bones

Risky Medicine: Our Quest to Cure Fear and Uncertainty

by Robert Aronowitz

Will ever-more sensitive screening tests for cancer lead to longer, better lives? Will anticipating and trying to prevent the future complications of chronic disease lead to better health? Not always, says Robert Aronowitz in Risky Medicine. In fact, it often is hurting us. Exploring the transformation of health care over the last several decades that has led doctors to become more attentive to treating risk than treating symptoms or curing disease, Aronowitz shows how many aspects of the health system and clinical practice are now aimed at risk reduction and risk control. He argues that this transformation has been driven in part by the pharmaceutical industry, which benefits by promoting its products to the larger percentage of the population at risk for a particular illness, rather than the smaller percentage who are actually affected by it. Meanwhile, for those suffering from chronic illness, the experience of risk and disease has been conflated by medical practitioners who focus on anticipatory treatment as much if not more than on relieving suffering caused by disease. Drawing on such controversial examples as HPV vaccines, cancer screening programs, and the cancer survivorship movement, Aronowitz argues that patients and their doctors have come to believe, perilously, that far too many medical interventions are worthwhile because they promise to control our fears and reduce uncertainty. Risky Medicine is a timely call for a skeptical response to medicine’s obsession with risk, as well as for higher standards of evidence for risk-reducing interventions and a rebalancing of health care to restore an emphasis on the actual curing of and caring for people suffering from disease.

The Impact of Inequality: How to Make Sick Societies Healthier

by Richard Wilkinson

A &“powerful and provocative&” inquiry into the relationship between societies&’ inequality and their citizens&’ health, happiness and well-being (Lisa Berkman, Harvard School of Public Health). Comparing the United States with other market democracies, and one American state with another, this book presents irrefutable evidence that inequality is a driver of poor health, social conflict, and violence. Pioneering social scientist Richard Wilkinson addresses the growing feeling—so common in the United States—that modern societies, despite their material success, are social failures. The Impact of Inequality explains why inequality has such devastating effects on the quality and length of our lives. Wilkinson shows that inequality leads to stress, which in turn creates sickness on the individual and mass level. As a consequence, society suffers widespread unhappiness and high levels of violence, depression, and mistrust across the social spectrum. With persuasive evidence and fascinating analysis, the diagnosis is clear: Social and political equality are essential to improving life for everyone. Wilkinson argues that even small reductions in inequality can make an important difference—for, as this book explains, social relations are always built on material foundations. &“This new book, a wonderful work of synthesis, brings insight into how conditions of society impact on people&’s daily lives. . . . It is a stimulating and exciting book.&” —Sir Michael Marmot, author of The Status Syndrome

Aquaculture and Conservation of Inland Coldwater Fishes

by Suresh Chandra Debajit Sarma Sumanta Kumar Mallik

This book provides the latest information on trans-Himalayan Hindu Kush Region (HKR) fisheries including the Indian Himalayan Region (IHR) as well as the historical context of its sustainable development for improving livelihood and nutritional security. The book serves as an important document to provide knowledge and information about the major concerns of environmental and anthropogenic factors that have impacted the population of certain important fishes in the ecosystem and the strategies and policies required for the conservation of these important groups of fishes, viz., Mahseer, snow trout, minor carp, catfishes, etc. The chapters describe the information to the readers on potential cold water and cool water fish species suitable for large-scale farming and propagation addressing the issues of diseases, nutrigenomics, and nanobiotechnology. This book also addresses the prospects and potential of recreational fishing in India and the scope for its improvement to generate more employment and income citing the success stories and primary information from reputed anglers. Finally, the book also elucidates a comprehensive yet representative description of many challenges associated with inland coldwater- cool water fisheries and aquaculture in HKR, IHR, and its way forward.

Biotechnology of Medicinal Plants with Antiallergy Properties: Research Trends and Prospects

by Amit Baran Sharangi Saikat Gantait Jayoti Majumder

This book comprehensively covers critically investigated information on medicinal plants prioritized for their anti-allergy properties. It offers insights into strategies related to the distribution, mechanism of action, and assessment of antiallergic medicinal plants, and also delves into crucial aspects of modern biotechnological tools, addressing their implementation challenges, presenting innovative approaches through case studies, and exploring opportunities for nanotechnologies. These elaborated discussions aim to raise awareness and bridge the gap between human health and the biodiversity of antiallergic medicinal plants. As the book navigates the uncertainties of plant-based medicines in the post-COVID-19 era, it provides real-world applications showcasing the specific utility of medicinal plants through advanced biotechnological insights. This book covers several medicinal plants associated with antiallergy, exploring their modes of action, available secondary metabolites,and estimation methods. It also emphasizes all modern biotechnological interventions aimed at propagating, multiplying, and conserving this unique treasure trove of medicinal plants. The World Health Organization estimated that 80% of the populations of developing countries rely on traditional medicines, mostly plant drugs, for their primary health care needs. Increasing demand in both developing and developed countries resulted in the expanding trade of medicinal plants and has serious implications for the survival of several plant species, with many under threat of becoming extinct. This book describes various approaches to conserving these genetic resources. It discusses the whole spectrum of biotechnological tools from micro-propagation for large-scale multiplication and cell-culture techniques to the biosynthesis and enhancement of pharmaceutical compounds in plants. It also discusses the genetic transformation as well as short- to long-term conservation of plant genetic resources via synthetic seed production and cryopreservation, respectively. This reference book is useful for researchers in the pharmaceutical and biotechnological industries, medicinal chemists, biochemists, botanists, molecular biologists, academicians, students as well as allergic patients, traditional medicine practitioners, scientists in medicinal and aromatic plants, and other traditional medical practitioners.

Eye of the Beholder: 'A haunting tale of intrigue' –Emily Freud

by Emma Bamford

'Eerie, atmospheric' Louise Jensen'A haunting tale of intrigue' Emily Freud'Ruth Ware fans will eat this up' Publishers WeeklyIf beauty is in the eye of the beholder, how much can you trust what you see? When Maddy Wight is hired to ghostwrite the memoir of world-renowned cosmetic surgeon Angela Reynolds, she jumps at the chance to get her career back on track. But the deeper she digs, the more elusive the doctor becomes. Confined to Angela&’s glass-walled house in the Scottish Highlands, Maddy can&’t shake the unsettling feeling of being watched. As a result, she is drawn ever closer to Angela&’s enigmatic business partner Scott, whose mercurial moods change as quickly as the darkening moors outside. Returning to London once the book is finished, Maddy is excited for their future together. But news of Scott&’s death shatters the celebrations at the book&’s launch party. Which is why, months later and still grieving, she is blindsided to see Scott entering a tube station just in front of her. And before she knows it, she is following him. In this reimagining of Hitchcock&’s Vertigo, jeopardy can be lurking where you least expect it…Praise for Emma Bamford 'Powered by a subtle, ominous tension. I loved this book&’ LEE CHILD &‘Paradise never felt so sinister&’ RUTH WARE &‘An incredible debut&’ B A PARIS &‘Suspenseful, evocative and beautifully written, I devoured it&’ L V MATTHEWS &‘That most exciting psychological thriller in which the darkest dangers lurk in a suspicious mind and a guilty heart&’ A J FINN &‘Gripping and pacy... A perfect summer read&’ IMRAN MAHMOOD &‘A debut thriller that unfolds with the inexorable force of a nightmare&’ JOHN CONNOLLY 'Had me gripped. I loved the subtle, sinister sense of tension that built through the book' BETH O'LEARY 'An amazing and evocative atmosphere of paradise that quickly turns sinister! A must summer read for all crime fans' VICKI BRADLEY

Unheard: The Medical Practice of Silencing

by Dr Rageshri Dhairyawan

Have you ever felt unheard by your doctor? Been frustrated that they haven't understood your symptoms, that they have neglected your concerns?When Dr Rageshri Dhairyawan was admitted to hospital as a patient she didn't receive the pain medication that she told them she needed, despite her being a senior doctor. It was in that moment she understood that something was deeply wrong with our healthcare system. Doctors aren't listening, and it is making us ill.In Unheard, Dr Dhairyawan takes us on a journey through history to show how not listening to patients has been ingrained in medicine from its inception. Western medicine has been built on the assumption that power should always lie with the doctor, and that patients should be powerless to decisions made about their body if it is done to make them well. This, alongside the prejudices of society, has led to dramatic gaps in medical knowledge because for centuries people have not been heard.Dr Dhairyawan offers a way to reshape our health system for a future where active and engaged listening is the new frontier in a timely, shocking and engaging exposé of the medical world.

How Herbs Healed the World: And Other Stories of Remarkable Plants

by Connor Smith

'The writing shines when recounting the stories behind these herbs, offering a blend of history and botanical fascination' - RHS, The GardenHerbs are wonderful things. Without them so much would not be possible. With the advance of science over the last two hundred years these once mystical plants have changed and saved countless lives, vastly improving our standard of living while providing us all with a much richer, healthier diet. Today, we take for granted a world full oflife-saving drugs, luxury cosmetics and exotic foods.This fascinating book will tell this story: revealing how poisons once used by the ancient Romans such as Deadly Nightshade are now being used in modern medicine or how the herbs used by indigenous people around the world have provided remedies for countless illnesses. It will explore the myths and legends behind herbs such as the infamous Mandrake and how herbs such as Yarrow are still being used to treat wounds today, just as they were thousands of years ago; and it will show how exotic herbs from across the globe have enriched our livesand delve into the origins of the culinary herbs that everyone knows and loves.Seventy-five herbs have been carefully chosen to tell the story of how they have each changed our world, looking back at their origins and what was once believed, while comparing this with the modern day uses and the scientific value of these plants enabling the reader to understand and appreciate their importance.Each double page spread will provide both historic and modern illustrations of each herb alongside captivating accounts of their historical and modern day uses including supplementary botanical and horticultural information for each.

Unheard: The Medical Practice of Silencing

by Dr Rageshri Dhairyawan

Have you ever felt unheard by your doctor? Been frustrated that they haven't understood your symptoms, that they have neglected your concerns?When Dr Rageshri Dhairyawan was admitted to hospital as a patient she didn't receive the pain medication that she told them she needed, despite her being a senior doctor. It was in that moment she understood that something was deeply wrong with our healthcare system. Doctors aren't listening, and it is making us ill.In Unheard, Dr Dhairyawan takes us on a journey through history to show how not listening to patients has been ingrained in medicine from its inception. Western medicine has been built on the assumption that power should always lie with the doctor, and that patients should be powerless to decisions made about their body if it is done to make them well. This, alongside the prejudices of society, has led to dramatic gaps in medical knowledge because for centuries people have not been heard.Dr Dhairyawan offers a way to reshape our health system for a future where active and engaged listening is the new frontier in a timely, shocking and engaging exposé of the medical world.

The Doctor's Rescue

by Kate Hardy

Rescuing Dr. CooperGP Dr. Will Cooper had rescued a toddler from a busy road but ended up in hospital himself, with a broken arm and leg and a beautiful stranger, Dr. Mallory Ryman, by hisbed! Mallory had been climbing in the area and had been the first doctor at the scene.Now Will was asking Mallory to be his locum—and live in his house so she could care for him until he recovered! But Mallory had no idea that her stay would force Will to confront some past traumatic events—nor that their mutual attraction would develop into an all consuming passion.…

How Herbs Healed the World: And Other Stories of Remarkable Plants

by Connor Smith

'The writing shines when recounting the stories behind these herbs, offering a blend of history and botanical fascination' - RHS, The GardenHerbs are wonderful things. Without them so much would not be possible. With the advance of science over the last two hundred years these once mystical plants have changed and saved countless lives, vastly improving our standard of living while providing us all with a much richer, healthier diet. Today, we take for granted a world full oflife-saving drugs, luxury cosmetics and exotic foods.This fascinating book will tell this story: revealing how poisons once used by the ancient Romans such as Deadly Nightshade are now being used in modern medicine or how the herbs used by indigenous people around the world have provided remedies for countless illnesses. It will explore the myths and legends behind herbs such as the infamous Mandrake and how herbs such as Yarrow are still being used to treat wounds today, just as they were thousands of years ago; and it will show how exotic herbs from across the globe have enriched our livesand delve into the origins of the culinary herbs that everyone knows and loves.Seventy-five herbs have been carefully chosen to tell the story of how they have each changed our world, looking back at their origins and what was once believed, while comparing this with the modern day uses and the scientific value of these plants enabling the reader to understand and appreciate their importance.Each double page spread will provide both historic and modern illustrations of each herb alongside captivating accounts of their historical and modern day uses including supplementary botanical and horticultural information for each.

The Italian Doctor's Proposal

by Kate Hardy

There’s no one else I would want to be the mother of my childrenPip Murdoch is torn. She is finally, for the first time in her life, experiencing real love. Toni Costa, the new Italian doctor on the ward, is making her feel things she’s never known. But she can’t give in to her heart. She has responsibilities that justwon’t allow it.The gorgeous Italian knows he can help Pip heal the rift between her and her young daughter. He’s determined to show her that he’ll never leave them, and that together they can be a real family.

Practical Human Behaviour Change for the Health and Welfare of Animals

by Bronwen Williams

Practical guidance to improving animal wellbeing by changing human behaviour Practical Human Behaviour Change for the Health and Welfare of Animals is the practical guide to helping people change behaviour for the welfare, wellbeing, and health of their animals. Grounded in evidence, this book enables readers to understand some of the underlying causes of human behaviour towards animals and deliver the crucial techniques and skills to help people make needed behavior changes. These techniques, including the use of the Stages of Change model, Motivational Interviewing (MI), and skilled Active Listening, support practical interventions for owner’s behaviors such as those around diet, exercise, weight control, and breeding; the text also supports professionals through difficult conversations such as euthanasia, hoarding, and giving up ownership. These approaches have been found to improve outcomes for animals as well as engagement with workers by owners. This way of working also reduces psychological burden on workers and help with job satisfaction. To aid in reader comprehension, Practical Human Behaviour Change for the Health and Welfare of Animals is complemented by case examples, analogies, and exercises. A supporting website provides worksheets and resources to further support the reader’s learning and help put skills into practice. Written by a highly qualified author with more than 20 years of experience in human behaviour change for animal welfare, the book discusses topics such as: What helps people change—and what doesn’t—covering traditional techniques that are less likely to help, and alternative methods that have been proven to support behavioral change in others Principles and key ideas underpinning motivational interviewing and active listening skills for motivational interviewing Structuring conversations with a focus, developing understanding of the owner’s situation and experiences, working with ambivalence, and supporting people to prepare for change Preparing for action via goal setting and action planning, supporting people to move into making changes and to maintain change in the long-term Practical Human Behaviour Change for the Health and Welfare of Animals is a valuable resource for veterinary surgeons, veterinary nurses, and animal care providers; it is also highly useful for animal welfare and sanctuary workers, animal rehoming workers, and individuals working in health, environmental, and trading standards where animal welfare issues are encountered.

The Virus and the Vaccine: Contaminated Vaccine, Deadly Cancers, and Government Neglect

by Debbie Bookchin Jim Schumacher

Jonas Salk's polio vaccine has taken on an almost legendary quality as a medical miracle, for it largely eradicated one of the most feared diseases of the 20th century. But the story of the vaccine has a dark side, one that has never been fully told before...Between 1954 and 1963, close to 98 million Americans received polio vaccinations contaminated with a carcinogenic monkey virus, now known as SV40. A concerted government effort downplayed the incident, and it was generally accepted that although oncogenic to laboratory animals, SV40 was harmless to humans.But now SV40 in showing up in human cancers, and prominent researchers are demanding a serious public health response to this forgotten polio vaccine contaminant. A gripping medical detective story, The Virus and the Vaccine raises major questions about vaccine policy.

Heal Thyself: A Doctor at the Peak of His Medical Career, Destroyed by Alcohol—and the Personal Miracle That Brought Him Back

by Olivier Ameisen

Heal Thyself is the paperback edition of The End of My Addiction—a memoir of Ameisen's struggle and a call to action."[This book is] the story of the dazzling discovery of a cure that could soon be within reach of all . . . you must read this book." —David Servan-Schreiber, MD, PHD, author of Healing Without Freud or Prozac and AnticancerWhen Olivier Ameisen's book was first published, Barbara Fisher noted in The Boston Globe that "this is not your usual memoir of addiction, degradation, and redemption." His story is indeed unusual—not because he was a brilliant cardiologist who developed a profound addiction to alcohol, or because he tried numerous treatment options and none helped. His story was the story of millions of alcoholics—until he decided to take his treatment into his own hands.Searching for a cure for his deadly disease, he happened upon baclofen, a safe muscle relaxant that had recently shown promising results in studies with laboratory animals addicted to a wide variety of substances. Ameisen experimented with increasingly higher dosages until he reached a level that left him free of any craving for alcohol. That was more than six years ago.In the past year, a growing number of researchers and doctors have been inspired by Ameisen and begun prescribing baclofen and lobbying for wide-scale studies into how the drug works. Last spring, no less an authority than the leading medical journal Alcoholand Alcoholism endorsed the book. Hailing Dr. Ameisen as "a remarkable medical researcher," it summed up its assessment strongly and directly: "This book is to be recommended."

Match Day: One Day and One Dramatic Year in the Lives of Three New Doctors

by Brian Eule

Three new doctors—all women—struggle to balance professional ambitions and personal relationships, triumphs and crises, uncertainties and decisions, through one pressure-packed day and the first year of their careers in medicine Each year, on the third Thursday in March, more than 15,000 graduating medical students exult, despair, and endure Match Day: the decision of a controversial computer algorithm, which matches students with hospital residencies in every field of medicine. The match determines where each graduate will be assigned the crucial first job as an intern, and shapes the rest of his—or, in increasing number, her—life. In Match Day, Brian Eule follows three women from the anxious months before the match through the completion of their first year of internship. Each woman makes mistakes, saves lives, and witnesses death; each must keep or jettison the man in her life; each comes to learn what it means to heal, to comfort, to lose, and to grieve, while maintaining a professional demeanor. Just as One L became the essential book about the education of young attorneys, so Match Day will be for every medical student, doctor, and reader interested in medicine: a guide to what to expect, and a dramatic recollection of a pressured, perilous, challenging, and rewarding time of life.

The Jupiter Plague

by Harry Harrison

Unexpectedly, the long-lost first manned Jupiter probe has returned--but only a madman would have tried to land it at Kennedy International!The result is the biggest air disaster in history. And that's only the beginning: now comes THE JUPITER PLAGUE.At the Publisher's request, this title is being sold without Digital Rights Management Software (DRM) applied.

rTMS-Behandlung bei Depressionen: Ein praktischer Leitfaden

by Z. Jeff Daskalakis Paul B. Fitzgerald

Die Behandlung mit repetitiver transkranieller Magnetstimulation (rTMS) wird zunehmend zum Standard bei der Behandlung von Patienten mit Depressionen, unterstützt durch eine rasch wachsende Forschungsbasis. Dieser prägnante klinische Leitfaden dient als Nachschlagewerk und praktisches Werkzeug für Kliniker, die mit dieser Behandlungstechnik arbeiten oder sie kennenlernen möchten. Die einleitenden Kapitel enthalten grundlegende Informationen über die Geschichte und Entwicklung der rTMS-Behandlung und ihren Wirkmechanismus. Die Anwendung der Behandlung bei Depressionen wird dann im Detail behandelt, wobei die Evidenzbasis erläutert und eine Vielzahl klinischer Fragen erörtert wird. Die Nebenwirkungen der Behandlung werden diskutiert, und die Einrichtung von rTMS-Behandlungsprogrammen wird erklärt. Es gibt einen aktualisierten Überblick über den Einsatz von rTMS-Anwendungen bei anderen psychiatrischen Erkrankungen wie Zwangsstörungen. Weitere Kapitel befassen sich mit dem Einsatzvon tiefer TMS, Theta-Burst-Stimulation, beschleunigten Formen der rTMS und was bei Patienten zu tun ist, die nicht auf die erste Therapie ansprechen. Darüber hinaus werden die verschiedenen Ansätze für eine zielgerichtete Behandlung im Detail dargestellt. Dieses Buch vermittelt dem rTMS-Praktiker und jedem Interessierten eine aktuelle und umfassende Übersicht und bietet umfangreiche praktische klinische Ratschläge.

Blood and Guts: A History of Surgery

by Richard Hollingham

Today, astonishing surgical breakthroughs are making limb transplants, face transplants, and a host of other previously un dreamed of operations possible. But getting here has not been a simple story of medical progress. In Blood and Guts, veteran science writer Richard Hollingham weaves a compelling narrative from the key moments in surgical history. We have a ringside seat in the operating theater of University College Hospital in London as world-renowned Victorian surgeon Robert Liston performs a remarkable amputation in thirty seconds—from first cut to final stitch. Innovations such as Joseph Lister's antiseptic technique, the first open-heart surgery, and Walter Freeman's lobotomy operations, among other breakthroughs, are brought to life in these pages in vivid detail. This is popular science writing at it's best.

Medical Image Computing and Computer Assisted Intervention – MICCAI 2023: 26th International Conference, Vancouver, BC, Canada, October 8–12, 2023, Proceedings, Part IX (Lecture Notes in Computer Science #14228)

by James Duncan Tanveer Syeda-Mahmood Hayit Greenspan Anant Madabhushi Russell Taylor Parvin Mousavi Septimiu Salcudean

The ten-volume set LNCS 14220, 14221, 14222, 14223, 14224, 14225, 14226, 14227, 14228, and 14229 constitutes the refereed proceedings of the 26th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2023, which was held in Vancouver, Canada, in October 2023. The 730 revised full papers presented were carefully reviewed and selected from a total of 2250 submissions. The papers are organized in the following topical sections: Part I: Machine learning with limited supervision and machine learning – transfer learning; Part II: Machine learning – learning strategies; machine learning – explainability, bias, and uncertainty; Part III: Machine learning – explainability, bias and uncertainty; image segmentation; Part IV: Image segmentation; Part V: Computer-aided diagnosis; Part VI: Computer-aided diagnosis; computational pathology; Part VII: Clinical applications – abdomen; clinical applications – breast; clinical applications – cardiac; clinical applications – dermatology; clinical applications – fetal imaging; clinical applications – lung; clinical applications – musculoskeletal; clinical applications – oncology; clinical applications – ophthalmology; clinical applications – vascular; Part VIII: Clinical applications – neuroimaging; microscopy; Part IX: Image-guided intervention, surgical planning, and data science; Part X: Image reconstruction and image registration.

Sensomotorische Einlagen: Grundlagen und Funktionen (essentials)

by Steven Simon Michael Fröhlich Stephan Becker Oliver Ludwig Stefan Woltring

In diesem essential finden Sie anatomische Grundlagen, Wirkidee und Einblicke in die handwerkliche Umsetzung von sensomotorischen Einlagen (SMFO), die zu einem transparenten Verständnis der Funktionsweise verhelfen. Diese Art der orthopädischen Hilfsmittelversorgung birgt viele positive Ansätze, insbesondere bei muskuloskelettalen Beeinträchtigungen und erweitert das Repertoire der individuellen Versorgungsmöglichkeiten.

Forensics and Fiction: Clever, Intriguing, and Downright Odd Questions from Crime Writers

by D. P. Lyle

How long can someone survive in a cold, damp cave without food or water? How was diphtheria treated in 1886? Can Botox kill? Can DNA be found on a knife years later? How are mummified corpses identified? How long does it take blood to clot when spilled on a tile floor? What happens in death from electrocution?As a consultant to many novelists around the world and to the writers of such popular TV shows as Monk, Law & Order, House, and CSI: Miami, D. P. Lyle, M.D., has answered many cool, clever, and oddball questions over the years. Forensics and Fiction: Clever, Intriguing, and Downright Odd Questions from Crime Writers is a collection of the best of these questions. The answers are provided in a concise and entertaining fashion that will keep you wide awake so you can read "just one more."

Poison Pills: The Untold Story of the Vioxx Drug Scandal

by Tom Nesi

To the millions of Americans who suffer from chronic pain and arthritis, Vioxx seemed like a miracle. One of the most widely promoted and prescribed pain medications in the world -- used by more than twenty million people -- it was endorsed by the medical establishment and celebrities such as Olympic champion figure skater Dorothy Hamill. With annual sales of $2.5 billion, Vioxx became a pharmaceutical bonanza before being abruptly taken off the market in September 2004, after it was revealed that it led to an increased risk of heart-related disease and death.Drawing on internal documents, video footage, court testimony, and exclusive interviews, as well as three decades of experience inside the medical industry, Tom Nesi tells the dramatic story of what the drug's manufacturer, Merck, knew and when. It is a compelling narrative of business and medical science run amok, with a cast of characters ranging from those at the highest levels of the multibillion-dollar pharmaceutical industry to research scientists, marketers, and drug company sales reps. Here also are accounts from physicians, lawyers, financial analysts, and patients and their families whose lives have been forever altered by Vioxx.Set against a fascinating history of the origins of the modern pharmaceutical industry, POISON PILLS is a shocking tale that involves the breakdown of the United States medical system, the failures of the Food and Drug Administration, and enormous profits made by a large pharmaceutical corporation at the potential cost of thousands of lives.

The Two Kinds of Decay: A Memoir

by Sarah Manguso

A Spare and Unsparing Look at Affliction and Recovery that Heralds a Stunning New Voice The events that began in 1995 might keep happening to me as long as things can happen to me. Think of deep space, through which heavenly bodies fly forever. They fly until they change into new forms, simpler forms, with ever fewer qualities and increasingly beautiful names.There are names for things in spacetime that are nothing, for things that are less than nothing. White dwarfs, red giants, black holes, singularities.But even then, in their less-than-nothing state, they keep happening.At twenty-one, just starting to comprehend the puzzles of adulthood, Sarah Manguso was faced with another: a wildly unpredictable disease that appeared suddenly and tore through her twenties, vanishing and then returning, paralyzing her for weeks at a time, programming her first to expect nothing from life and then, furiously, to expect everything. In this captivating story, Manguso recalls her nine-year struggle: arduous blood cleansings, collapsed veins, multiple chest catheters, the deaths of friends and strangers, addiction, depression, and, worst of all for a writer, the trite metaphors that accompany prolonged illness. A book of tremendous grace and self-awareness, The Two Kinds of Decay transcends the very notion of what an illness story can and should be.

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