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Biomedical Innovation in Fertility Care: Evidence Challenges, Commercialization, and the Market for Hope
by Manuela PerrottaAvailable Open Access digitally under CC-BY-NC-ND licence.This book analyses the clashes between evidence-based medicine and the dynamics of an increasingly privatised fertility care industry. With a unique focus on "add-on" treatments, it reveals how these controversial treatments are now widespread and can border on hopemongering.
Anatomical Segmentectomy for Lung Cancer: Illustration and Videos
by Hiroaki NomoriThis book explains more than 30 types of segmentectomy with plentiful figures to explain the intraoperative findings and anatomy of the lung. It also provides videos to help readers recognize the tricks and techniques that are not explained in still images. The book is organized into four parts following the anatomy of the lung; right upper lobe, right lower lobe, left upper lobe, and left lower lobe. Each chapter goes into detail on each segment and offers the latest devices and procedures. Although segmentectomy is known as curative surgery for early-stage small lung cancers, not many surgeons can perform with accuracy due to its anatomical complexity. Therefore, the purpose of Anatomical Segmentectomy for Lung Cancer is to share the knowledge and experiences of performing the surgeries and to further enhance the techniques by creating a foundation for building on to this knowledge. It is a valuable resource for thoracic surgeons interested in curative surgery for small lung cancers and for those who wish to stay up to date on the latest techniques.
Complications of Cancer Therapy: Best Practices in Prevention and Management
by Gaurav Sood Kanika Sood Sharma Raajit ChananaThis book covers the diverse complications noted in medical, radiation, surgical and pediatric oncology. The various chapters target the common complications that the clinicians encompass in the practice day in and day out. It assists in identifying/ stratification the patients at higher risk of complications so that they may be offered alternative options or get a de-intensified treatment. It also covers the determinants/predictors-clinical alarm signs or the safety flags associated with specific high-risk procedures. The chapters are designed to offer a preventive strategy to reduce the incidence of complications, such as the early introduction of corrective measures, supportive care measures, and refining the procedure in case of anticipated risk of certain complications. The manual addresses the management strategies of complications and will propose a formulation of treatment policies as per the severity of the disease. Manual includes discussion on evidence-based treatment strategies and recent advances in management. It consists of a summarized algorithm on leadership based on guidelines (if available). Since it is a multimodality approach-based book, it is an exciting read to the students and the practitioners of medical, surgical, radiation, and nursing. It addresses the disclosure of complications and the medicolegally correct way of taking consent for complications.
Homeopathy as Energy Medicine: Information in the Nanodose
by Richard Grossinger• Comprehensively examines what homeopathy is and places the practice within the larger framework of energy medicine and microdose effects• Lays out the principles and origins of homeopathy, explaining its discovery and development by Samuel Hahnemann• Explores the rise and fall and current rise in popularity of homeopathy over the years and its resonance during the COVID-19 pandemicHelping first-time patients as well as longtime devotees gain a deeper understanding of just what homeopathy is, Richard Grossinger presents a comprehensive overview of the healing art, explaining its essential philosophy and methodology and showing how it relates to the broader concepts of energy medicine and nanodose treatments. He introduces homeopathy&’s basic framework and explores its three central principles: the Law of Similars, microdose transmission of energetic information, and potentization. Addressing the many critiques of homeopathy, he looks at the power of the placebo effect and offers a comparison of homeopathy to other alternative and mainstream healing modalities.Placing homeopathy in a historical context, he explores doctor Samuel Hahnemann&’s discovery of homeopathy in the late 18th century and looks at medical and pharmaceutical systems that preceded homeopathy, such as alchemy, Paracelsan herbalism, and Greek and Roman medicine. He examines homeopathy&’s rise and fall in popularity over the years, including its renaissance in early 19th-century North America and its revival in the counterculture of the 1970s. He looks at modern evolutions of homeopathy, including Dr. Rajan Sankaran&’s "sensations" theory, homeopathy&’s resonance during the COVID-19 pandemic, the concept of the pill-less pharmacy, the microdose basis of astrological charts, and psychic homeopathy.Presenting a contemporary understanding of homeopathy as energy medicine, this book offers everything needed to begin self-healing with the power of the nanodose.
Anti-SARS-CoV-2 Activity of Flavonoids
by Jen-Tsung ChenIn the past years, COVID-19 caused millions of deaths and severely damaged not only public health, but also the global economy. New variants continue to threaten human health. Thus, natural compounds for retarding infection are in high demand. This book summarizes the emerging research with flavonoids, whose application holds great promise of antivirus, anti-inflammation, antioxidative stress, and immunomodulatory. Topics include the role of flavonoids in preventing an inflammatory storm and how flavonoids interact with critical protein targets that are involved in the infection stages of COVID-19.Key Features• Highlights anti-SARS-CoV-2 drug discovery on natural products and medicinal plants• Includes all major subclasses of flavonoids that promisingly combat COVID-19 • Proposes molecular mechanisms of flavonoids against protein targets of SARS-CoV-2• Contributions from an international team of leading researchers• Provides recommendations with respect to the future research
Advanced Soft Electronics in Biomedical Engineering: Materials, Manufactures, and Applications
by Mengxiao ChenThe book presents the latest advances in soft electronics in biomedical engineering and its potential applications in various biomedical fields.The contributors provide comprehensive coverage of how soft electronics are used in diagnostics and monitoring, medical therapy, neural engineering, and wearable and implantable systems. In particular, some emerging research areas such as advanced soft robotics, fiber sensing technologies, and power optimization strategies are explored. In addition, the book highlights international standardization activities in wearable technologies and implantable bioelectronics.The book will benefit researchers, engineers, and advanced students in biomedical engineering, electrical and computer engineering, and materials science.
Telltale Hearts: A Public Health Doctor, His Patients, and the Power of Story
by Dean-David SchillingerIn this illuminating work, a doctor and public health advocate reveals what his patients have taught him about patience and healing. For over three decades, Dr. Dean-David Schillinger has served in one of the country&’s busiest and most important public hospitals. A public health leader and primary care physician for underserved patients, Schillinger learned that high-tech tests and novel medications are often not enough to save lives. Rather, accurate diagnosis, treatment and true healing come from listening deeply to patients and their stories. In Telltale Hearts, Schillinger reveals what is lost when patients&’ stories are ignored or overlooked, and how much is gained when these stories are actively elicited. The stories themselves, at times shocking and always revelatory, disclose secrets, prompt awe, forge unexpected connections, and even catalyze public health action.Telltale Hearts serves as a call to action, urging us to reshape public policy to improve the nation's health.
Green Rush: The Rise of Medical Marijuana in the United States
by Daniel J. Mallinson A. Lee HannahA state-by-state analysis of the expansion of medical marijuana access in the United StatesAs of 2023, thirty-eight states and the District of Columbia have legalized the medical use of marijuana. Twenty-three have legalized recreational use, supporting what is now a flourishing multibillion-dollar industry. In Green Rush, Daniel J. Mallinson and A. Lee Hannah offer a fascinating history of cannabis legalization in America, highlighting the people, states, and policies that made these victories possible.With sharp insight, Mallinson and Hannah explore the backdrop to this sea change in policy, including shifts in public opinion, growing opposition to the War on Drugs, the promise of new revenue streams, and more. They examine the complex web of state actors—and the steps they took—to chart a path forward for marijuana legalization, from grassroots activists and interest groups to elected officials and other key policymakers.Mallinson and Hannah show us how states like Pennsylvania, Ohio, and West Virginia not only created, legitimized, and spread medical marijuana policy but also learned from each other’s successes and failures throughout the process. As marijuana legalization increasingly finds its way onto state ballots, Green Rush offers fresh insight into how we got here as a country and where we are going—one state at a time.
The Neuroscience of Psychotherapy: Healing the Social Brain (IPNB #0)
by Louis CozolinoA new edition of the classic text that links neuroscience and human behavior in a therapeutic context. This groundbreaking book explores the revolution in psychotherapy that brought an understanding of the social nature of people’s brains into a therapeutic context. Louis Cozolino is a master at synthesizing neuroscience and demonstrating how it applies to psychotherapy practice. Here, he argues that all forms of psychotherapy are successful to the extent to which they enhance change in relevant neural circuits. Beginning with an overview of the intersecting fields of neuroscience and psychotherapy, this book delves into the brain’s inner workings, from basic neuronal building blocks to complex systems of memory, language, and the organization of experience. In this updated edition, readers will also find new content on the evolutionary foundations of psychotherapy; the necessity of gaining broad perspectives on mind, brain, and culture in clinical training; the importance of interpreting research with the human brain’s biases in mind; the debatable applicability of Eurocentric perceptions of “self”; and more.
Planning & Designing Health Care Facilities in Developing Countries
by Saurabh Singh Shashikant SharmaBuilding a clinically integrated workplace with a high level of clinical competence requires careful considerations of Hospital Planning. For greenfield or brownfield hospital projects, clinicians and C-Suite executives need to acquire capabilities to address the planning needs of any organization. This book aims to provide both theoretical and practical inputs for the Planning & Designing of Health Care Facilities in Developing Countries. It clearly indicates the steps to be followed, facts to be weighed, and components to be considered to arrive at a correct planning solution. With health reform looming and the revenue base shifting rapidly, we need to integrate patient safety concerns in the design process. Key Features• Liberal use of tables and figures to support conclusions, illustrate concepts, and display quantitative information, making it easier for readers to understand and refer to large quantities of data• Integrates the international norms for planning and designing health care facilities into the developing country setting• Handbook and ready reckoner for C-Suite executives, hospital engineers, project consultants, and hospital administration students
Sheep Veterinary Practice
by Kym A Abbott“The value of this book cannot be overstated. As a student, many years ago, there were no comprehensive textbooks on sheep medicine, so I was lucky to have Professor Kym A Abbott as an inspiring lecturer. This book is needed by students!” Following on from Professor Abbott's first book, The Practice of Sheep Veterinary Medicine, this new text remains the ideal reference for veterinarians in farm animal practice, veterinary and animal science students, agriculturalists and sheep producers. Principally addressing sheep health, welfare and production matters in Australia, this book also covers issues that are of relevance in many other countries of the world where sheep are raised. Sheep veterinary specialist Professor Kym Abbott and his co-authors inform the reader of the science underpinning the occurrence of disease syndromes, giving special attention to commonly investigated problems related to nutrition, reproduction and helminthiasis. Other disease conditions of sheep are discussed in subsequent chapters; first on the basis of presenting signs in the case of lameness and sudden death – conditions in which signs can be attributed to disorders of a variety of body systems – and then on a body-systems basis. This new edition thoroughly revises and expands on the previous text, adding a review of the systems and strategies available to improve the welfare of sheep in extensive farming systems, a chapter on pain relief, analgesia and anaesthesia for sheep, and a chapter on metacestodes.The text is illustrated with more than 150 full-colour images and photographs.
Are We the Next Endangered Species?: Bioweapons, Eugenics, and More
by Dr. Richard M. FlemingAre We the Next Endangered Species? unravels the complex web of historical events, misinformation, and the ominous convergence of bioweapons and eugenics In this thought-provoking new book, Dr. Fleming challenges us to navigate the murky waters of history, exposing parallel programs developed over the last 170 years in the United States. This riveting exploration unearths ancient civilizations that embraced slavery, sterilization, and eugenics, drawing chilling parallels to our present reality. Dr. Fleming confronts the uncomfortable truth: are we repeating the mistakes of the past while expecting different outcomes? Are we destined to replicate the errors that led to the rise of powerful individuals and organizations seeking ultimate control over others? Key revelations include the stealthy usurpation of power in the United States since the 1850s, the nation's pivotal role in developing biological and chemical weapons, and its shocking collaboration with Nazi scientists, doctors, and intelligence officers. Dr. Fleming unveils the shadowy world of covert operations, the establishment of the military-industrial complex, and the surrender of medical control to the federal government. Readers will discover the intricate pathways of biowarfare and eugenics converging with the emergence of COVID. They will learn about the gain-of-function bioweapons responsible for the pandemic and the parallel development of eugenic genetic vaccines. Fleming reveals the control wielded by the military-industrial complex and world leaders over your life, movement, property, and freedoms. This book is not just an exploration of the past or a revelation of how those in power are on the brink of realizing their ultimate control, it's a call to action. It doesn't just raise awareness—it empowers readers to understand, question, and take decisive action to halt the ominous path we're on. In a world where truth is elusive and power is coveted, this book is a beacon of knowledge, urging you to discover what you can do to stop the impending threats to our existence. The future hangs in the balance and Are We the Next Endangered Species? provides the roadmap to safeguard it.
Lebensbilder aus der Geschichte der Herzchirurgie
by Herbert E. UlmerBedeutende Persönlichkeiten, deren Namen für entscheidende Neuerungen in der Kinderherzchirurgie und Kinderkardiologie stehen, werden im Sinne eines "historischen Feuilletons" vorgestellt und charakterisiert, ihr Werk wird in den jeweiligen historischen, geistes- und wissenschaftsgeschichtlichen Kontext gestellt. Ein Blick in die spannende Entwicklung der Fachgebiete, der zugleich die Voraussetzungen für zukünftige Ideen und Problemlösungen aufzeigt.
Madness, Psychiatry, and Empire in Postcolonial Literature (Palgrave Studies in Literature, Science and Medicine)
by Chienyn ChiMadness, Psychiatry, and Empire in Postcolonial Literature provides a comparatist interrogation of empire through archives of history, science, and literature. The book analyzes Aimé Césaire’s Discourse on Colonialism to shed light on Césaire’s critique of psychological and medical discourses of the colonized’s mind. The book argues that the discourse of psychiatry, psychology, and psychoanalysis has erased the context of power in global histories of empire. Through the book’s chapters, Chi analyzes Lu Xun’s “A Madman’s Diary,” Virginia Woolf’s Mrs. Dalloway, and Tsitsi Dangarembga’s Nervous Conditions to assert that the misapprehension of madness should not automatically be accepted as the history of an isolated Western culture but rather that of the history of imperialism—a globalizing process that silences alternative cultural conceptions of the mind, of madness, and of behavior, as well as different interpretations of madness.
Veterinary Psychiatry of the Dog: Diagnosis and Treatment of Behavioral Disorders
by Sylvia Masson Stéphane Bleuer-Elsner Gérard Muller Tiphaine Medam Jasmine Chevallier Emmanuel GaultierThis richly illustrated textbook delivers a functional vision of dog behaviors. Daily applicable, it offers practical solutions for canine behavioral care with a consistently medical approach to disorders. Readers find a thorough introduction to factors influencing behavior, the canine neuroanatomy and physiology, psychopathologies, as well as treatment options. Drawing on the latest studies in neuroscience, ethology, psychology, and psychiatry, as well as the clinical experience of its expert authors, this guide is both comprehensive and accessible. Multiple clinical case studies illustrate and support presented details on medication and therapies.Behavioral pathology is one of the main challenges in veterinary medicine. Not only are they a cause of suffering for the animal, but they can also affect the quality of the relationship with the pet owners or pose a danger to society. Hence, treatment of these behavioral disorders requires an integrative approach to canine healthand well-being.The book's easy-to-access and descriptive structure allows many audiences to understand a subject area that is all too often considered complex. It addresses veterinary students, practitioners, and future expert veterinarians seeking approach to deep knowledge, as well as all other dog professionals curious to discover a complementary view with respect for the animal and owner.
Proceedings of the 14th International Symposium on Computer Science in Sport (Lecture Notes on Data Engineering and Communications Technologies #209)
by Hui Zhang Martin Lames Arnold Baca Yingcai WuThis book is a compilation of selected papers from the 14th International Symposium on Computer Science in Sport (IACSS 2023), held on September 27-30, 2023 in Hangzhou, China. The work focuses on the application of computer science and technology in the field of sports (such as intelligent data collection, data mining, visual analysis of game data, virtual reality, machine learning, computer vision, match prediction models and performance analysis). The contents make valuable contributions to academic researchers, college students, coaches and athletes, and sports management personnel (such as managers of sports associations, training bases, and professional clubs). Additionally, readers will encounter new ideas for realizing a more efficient and convenient training and exercise system.
A Dictionary and Phrasebook of French Medical Terms: With an Introduction to the French Medical System
by Richard WhitingWhether you are resident in France or simply visiting, this up-to-date and easy-to-use dictionary of French medical terms will help you deal with any medical or health situation. Includes hundreds of technical words you won’t find in an ordinary dictionary, all contained in a book you can take to the surgery or pharmacy.
Antimicrobial Resistance of the Human Eye
by S. ShivajiThe book covers antimicrobial resistance in ocular diseases, including the microbiology of the ocular surface, the history and origin of antimicrobials, methods to detect antimicrobial resistance and antimicrobial resistance genes, and the impact of antimicrobial resistance on a variety of ocular diseases. The inclusion of chapters covers bacterial keratitis, fungal keratitis, viral keratitis, acanthamoeba keratitis, endophthalmitis, dry eye disease, post fever retinitis, and uveitis including management and prevention of antimicrobial resistance.Key Features: Focusses on various ocular diseases and their association with antimicrobial resistance; Includes data relevant to drug industry to develop drugs for specific ophthalmic use; Illustrates ocular surface microbiome under various diseased condition;s Highlights the microbes associated with the conjunctiva and cornea of the human eye; Enumerates the changes in the abundance and diversity of the antimicrobial resistant (AMR) microorganisms in the diseased eye. This book is aimed at professionals and researchers in ophthalmology, microbiologists, infectious disease specialists, and public health.
On the Fractal Language of Medicine (Fractional Order Thinking in Exploring the Frontiers of STEM)
by Bruce J. West W. Alan MutchOn the Fractal Language of Medicine bridges a very clear gap among the knowledge gained over the last 20 years in the physical and life sciences on network theory, organ synchronicity and communication, the understanding of fractal signatures in health and disease and the importance of fractional calculus in integrating these concepts.The authors opine that the field of medicine has not appreciated this hard-won knowledge and has suffered greatly as a result. This book addresses this perceived deficiency by introducing medical researchers, clinicians, residents, first-year medical students and members of allied fields to the work of the so-called hard sciences. It seeks to facilitate effective communication between empiricists and theorists by making interdisciplinary efforts to explain complex mathematical concepts to physicians and, equally important, to elucidate complex medical concepts to physicists or mathematicians.This book will be of great interest to medical students, professionals and academics, as well as students and researchers of applied mathematics, especially those interested in fractional calculus and fractals.
Food Economics: Agriculture, Nutrition, and Health (Palgrave Studies in Agricultural Economics and Food Policy)
by William A. Masters Amelia B. FinaretFood Economics provides a unified introduction to the economics of agricultural production, business decisions, consumer behavior, and the government policies that shape our food system. This open access textbook begins with economic principles derived using graphical techniques to explain and predict observed prices, quantities, and other outcomes as a result of individual choices influenced by market structure and public policies. The second half of the book explores available data globally and for the US, covering a wide range of questions in agriculture and economic development, food marketing, and consumption. Food Economics and its accompanying online resources are designed for advanced undergraduate or introductory graduate courses in agriculture, food, and nutrition policy. The book covers the standard diagrams taught in principles-level courses, with concrete examples and practical insights regarding food production, consumption, and trade. Online resources include data sources, and course materials, including slides, exercises, exams, and answer keys.
Critical Care Echocardiography: A Self- Assessment Book
by Patrick Collier Roshni Sreedharan Sandeep Khanna Ajit Moghekar Siddharth DugarThis book provides practice questions in a case-based format to prepare for the National Board of Echocardiography’s examination to assess “Special Competence in Critical Care Echocardiography”.Focused on the exam's core topics, this textbook caters to physicians who are preparing for the Critical Care Echocardiography board examination. Defining features of each chapter include case based scenarios with videos and supporting images, meaningful and relevant multiple-choice questions, key take-aways and a summary. This book is the product of a multidisciplinary collaboration between ICU physicians (Pulmonary, Internal Medicine and Anesthesiology), Cardiologists, and Anesthesiologists.This book meets the needs of physicians from various disciplines preparing for the critical care echocardiography board examination.
Diagnostiek van alledaagse klachten: Bouwstenen voor klinisch redeneren
by T.O.H. de Jongh H. De Vries B. J. Knottnerus P.A.J. Keurlings J. Damen M. E. ReindersDiagnostiek is een van de moeilijkste aspecten van de medische praktijk; moeilijk om te doen en nog moeilijker om te leren. De afgelopen decennia is er in het medisch curriculum dan ook in toenemende mate aandacht gekomen voor het onderwijs in klinisch redeneren. Daarbij speelt dit boek Diagnostiek van alledaagse klachten een belangrijke rol.De meeste leerboeken gaan uit van aandoeningen en ziekten, maar mensen komen met klachten en symptomen naar de arts. Daarom geeft dit boek de logische en wetenschappelijke onderbouwing voor de diagnostiek van bijna 70 veelvoorkomende klachten.Elk hoofdstuk in dit boek behandelt de diagnostiek van een klacht volgens een vaste structuur: de incidentie van de klacht, hoe patiënten de klacht ervaren, redenen om ermee naar de arts te gaan, de mogelijke oorzaken en de differentiële diagnose. Vervolgens licht het boek de waarde toe van de gegevens uit anamnese, lichamelijk onderzoek en aanvullend onderzoek met betrekking tot de mogelijke diagnosen. De hoofdstukken zijn geschreven door huisartsen en vakspecialisten samen, allen met veel onderwijs- en praktijkervaring.Bij dit boek hoort een website, die kosteloos toegankelijk is voor de lezer. Daar is de gehele boekinhoud geplaatst, waardoor Diagnostiek van alledaagse klachten snel te doorzoeken en overal online te raadplegen is. Daarnaast staat er van iedere klacht een instructief consultfilmpje of een casus op de website, met bijbehorende verdiepingsvragen.Voor deze vijfde druk is de inhoud aangevuld en geactualiseerd en het boek is uitgebreid met een nieuw klacht: scrotale klachten en enkele algemene hoofdstukken.Diagnostiek van alledaagse klachten is bestemd voor studenten in het basiscurriculum, artsen in opleiding en praktiserende artsen. Daarnaast is het ook belangrijk voor docenten, paramedisch beroepsbeoefenaren en alle artsen die de rationaliteit van hun diagnostisch handelen kritisch willen beoordelen.
Geriatrics Models of Care: Bringing 'Best Practice' to an Aging America
by Heidi White Marie Boltz Michael L. Malone Jonny Macias TejadaFollowing the success of the previous edition, the second edition of Geriatrics Models of Care is the definitive resource for systems-based practice improvement for the care of older adults. Several new models of care have been published in the last eight years, new outcomes have emerged to better understand the impact of existing models, and with the rise of the Age-Friendly Health Systems movement, promoting organized efforts to prepare our health care settings for older individuals is of more importance than ever. The second edition is organized based on the practice setting along a continuum of care: hospital, transitions from hospital to home, outpatient settings, and the emergency department. This book also highlights long-term care models, which is an important part of the continuum of care for older Americans. Further, this edition features models that address the needs of vulnerable populations. This new section will describe a spectrum of programs for older adults who have Alzheimer’s disease or Parkinson’s disease. Other models describe best practices for older adults undergoing surgery or those who want to remain functioning independently in their home. A defining feature of this book is that each chapter follows a standard template: 1) the challenge which led to the model; 2) the patient population served; 3) core components of the intervention; 4) the role of interdisciplinary health professionals; 5) evidence to support the intervention; 6) lessons learned in the implementation and dissemination of the model; 7) implications for family caregivers, and communities (particularly underserved and diverse communities); and 8) how each model will provide care across the continuum during an entire episode of care. In addition, each chapter features a “call out” box with practical tips for implementing the model.
Endoscope-controlled Transcranial Surgery: Advancing the Standard of Intraoperative Visualization - Vol. 52 (Advances and Technical Standards in Neurosurgery #52)
by Waleed Abdelfattah AzabThis book addresses the fully endoscopic or endoscope-controlled transcranial surgery. As a surgical philosophy, it entails that the whole procedure is performed through a tailored keyhole craniotomy under the exclusive control of the rigid endoscope without the use of other visualization tools like surgical microscopes or exoscopes. Despite the well-known extreme superiority of the endoscopic view, especially at deep surgical targets, performing surgery under pure endoscopic control is currently adopted by few neurosurgeons across the globe. The main objective of this book to shed the light on this minimally-invasive surgical methodology and demonstrate its advantages and practical do ability. Many internationally renowned expert neurosurgeons thoroughly describe how these procedures are performed using detailed descriptions of the surgical techniques and high-quality illustrations and exquisite intraoperative endoscopic images. Endoscope-controlled Transcranial Surgery will be a valuable guide to practicing neurosurgeons in raising the bar of intraoperative visualization, with a consequent great improvement of safety and efficacy of the procedure performed. Furthermore, the book will serve as a starting point for more widespread utilization and dispersion of this surgical philosophy in the future.
Transcription factors in blood cell development (Advances in Experimental Medicine and Biology #1459)
by Tilman Borggrefe Benedetto Daniele GiaimoThis book describes transcription factors in the context of hematopoietic development and reveal mechanistic insights how they orchestrate specific gene expression patterns. Several examples from lymphoid and myeloid lineages are given as well as particular examples of leukemia fusion proteins that contain a part of a transcription factor. In the given chapters covering each one particular example, the function of transcription factors is characterized in normal as well as leukemic contexts. New technologies such as ChIP-Seq or RNA-Seq, that make use of genome-wide sequencing, have shown that such master regulators of blood cell development often work in combinatorial fashion and, when dysregulated, results in leukemogenesis. This book is not only intended for experts but it should also be a useful resource for younger scientists or scientists from other disciplines, who may use this book as a stimulating starting point for further discoveries and/ or translational endeavors.