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Nanoparticulate Drug Delivery Systems: Strategies, Technologies, and Applications
by Yoon YeoFrank discussions of opportunities and challenges point the way to new, more effective drug delivery systems Interest in nanomedicine has grown tremendously, fueled by the expectation that continued research will lead to the safe, efficient, and cost-effective delivery of drugs or imaging agents to human tissues and organs. The field, however, has faced several challenges attempting to translate novel ideas into clinical benefits. With contributions from an international team of leading nanomedicine researchers, this book provides a practical assessment of the possibilities and the challenges of modern nanomedicine that will enable the development of clinically effective nanoparticulate drug delivery products and systems. Nanoparticulate Drug Delivery Systems focuses on the rationales and preclinical evaluation of new nanoparticulate drug carriers that have yet to be thoroughly reviewed in the literature. The first chapter sets the stage with a general overview of targeted nanomedicine. The book then explores new and promising nanoparticulate drug delivery systems, including: Lipid nanoparticles for the delivery of nucleic acids Multifunctional dendritic nanocarriers Polymer drug nanoconjugates Next, the book presents new opportunities and challenges for nanoparticulate drug delivery systems, including: Clearance of nanoparticles during circulation Drug delivery strategies for combatting multiple drug resistance Toxicological assessment of nanomedicine Chapters offer state-of-the-technology reviews with extensive references to facilitate further investigation. Moreover, each chapter concludes with an expert assessment of remaining challenges, pointing the way to solutions and new avenues of research. With its frank discussions of opportunities and challenges, Nanoparticulate Drug Delivery Systems sets a solid foundation for new research leading to the discovery and development of better nanomedicines.
Handbook of Multiphase Flow Science and Technology
by Guan Heng Yeoh Jyeshtharaj B. JoshiThis Handbook provides readers with the current cutting edge of multiphase flow technology. It reviews the rapid development of multiphase flow technology, demonstrates the latest development of the technology and showcase the very latest applications. It provides readers with comprehensive updated reference information covering theory, modelling and numerical methods, design and measurement, and new applications in multiphase flow systems.The Handbook consists of three parts or volumes:1. Theory: describes the fundamentals including the concepts and definitions of multiphase flows. Classifications of multiphase flows. Basic understanding of different length scales involved – micro/nano, meso and macro. Treatment of such flows by different solution frameworks.2. Modelling and Measurement: covers both classical and state-of the-art measurement and modelling approaches to resolve different classifications of multiphase flows. 3. Applications: highlights the very latest applications of measurement and modelling approaches in tackling different classification of multiphase flows in a variety of natural, biological and industrial systems and different length scales.
4th International Conference on Electronics and Signal Processing: ICESP 2023 (Signals and Communication Technology)
by Seokwon YeomThis book presents the proceedings of the 4th International Conference on Electronics and Signal Processing (ICESP 2023), which was held in Macau, China during January 13-15, 2023. The book consists of contributions from various authors from both academia and industry, focusing on a diverse aspect of signal processing and information communication systems. The published papers suggest cutting-edge solutions that contribute to the quest for the future applications and communicating systems. The book is a useful reference to research students, research fellows, and scientists and engineers in the corresponding fields.
How Structures Work
by David YeomansStructural engineering is central to the design of a building. How the building behaves when subjected to various forces - the weight of the materials used to build it, the weight of the occupants or the traffic it carries, the force of the wind etc - is fundamental to its stability. The alliance between architecture and structural engineering is therefore critical to the successful design and completion of the buildings and infrastructure that surrounds us. Yet structure is often cloaked in mathematics which many architects and surveyors find difficult to understand. How Structures Work has been written to explain the behaviour of structures in a clear way without resorting to complex mathematics. This new edition includes a new chapter on construction materials, and significant revisions to, and reordering of the existing chapters. It is aimed at all who require a good qualitative understanding of structures and their behaviour, and as such will be of benefit to students of architecture, architectural history, building surveying and civil engineering. The straightforward, non-mathematical approach ensures it will also be suitable for a wider audience including building administrators, archaeologists and the interested layman.
Advances in Energy, Environment and Materials Science: Proceedings of the 2nd International Conference on Energy, Environment and Materials Science (EEMS 2016), July 29-31, 2016, Singapore
by Yeping Wang and Shiquan ZhouThe 2016 International Conference on Energy, Environment and Materials Science (EEMS 2016) took place on July 29-31, 2016 in Singapore. EEMS 2016 has been a meeting place for innovative academics and industrial experts in the field of energy and environment research. The primary goal of the conference is to promote research and developmental activities in energy and environment research and further to promote scientific information exchange between researchers, developers, engineers, students, and practitioners working all around the world. The conference will be organized every year making it an ideal platform for people to share views and experiences in energy, environment and materials science and related areas.
The Quest: Energy, Security and the Remaking of the Modern World
by Daniel YerginSelected by The New York Times Book Review as a Notable Book of the Year. In this gripping account of the quest for the energy that our world needs, Daniel Yergin continues the riveting story begun in his Pulitzer Prize-winning book, The Prize. A master storyteller as well as a leading energy expert, Yergin shows us how energy is an engine of global political and economic change. It is a story that spans the energies on which our civilization has been built and the new energies that are competing to replace them. From the jammed streets of Beijing to the shores of the Caspian Sea, from the conflicts in the Mideast to Capitol Hill and Silicon Valley, Yergin takes us into the decisions that are shaping our future. The drama of oil-the struggle for access, the battle for control, the insecurity of supply, the consequences of use, its impact on the global economy, and the geopolitics that dominate it--continues to profoundly affect our world. Yergin tells the inside stories of the oil market and the surge in oil prices, the race to control the resources of the former Soviet empire, and the massive mergers that transformed the landscape of world oil. He tackles the toughest questions: Will we run out of oil? Are China and the United States destined to come into conflict over oil? How will a turbulent Middle East affect the future of oil supply? Yergin also reveals the surprising and sometimes tumultuous history of nuclear and coal, electricity, and the "shale gale" of natural gas, and how each fits into the larger marketplace. He brings climate change into unique perspective by offering an unprecedented history of how the field of climate study went from the concern of a handful of nineteenth- century scientists preoccupied with a new Ice Age into one of the most significant issues of our times. He leads us through the rebirth of renewable energies and explores the distinctive stories of wind, solar, and biofuels. He offers a perspective on the return of the electric car, which some are betting will be necessary for a growing global economy. The Quest presents an extraordinary range of characters and dramatic stories that illustrate the principles that will shape a robust and flexible energy security system for the decades to come. Energy is humbling in its scope, but our future requires that we deeply understand this global quest that is truly reshaping our world.
Establishing Scientific Classroom Discourse Communities: Multiple Voices of Teaching and Learning Research
by Randy Yerrick Wolff-Michael RothEstablishing Scientific Classroom Discourse Communities: Multiple Voices of Teaching and Learning Research is designed to encourage discussion of issues surrounding the reform of classroom science discourse among teachers, teacher educators, and researchers. The contributors--some of the top educational researchers, linguists, and science educators in the world--represent a variety of perspectives pertaining to teaching, assessment, research, learning, and reform. As a whole the book explores the variety, complexity, and interconnectivity of issues associated with changing classroom learning communities and transforming science classroom discourse to be more representative of the discourse of scientific communities. The intent is to expand debate among educators regarding what constitutes exemplary scientific speaking, thinking, and acting. This book is unparalleled in discussing current reform issues from sociolinguistic and sociocultural perspectives. The need for a revised perspective on enduring science teaching and learning issues is established and a theoretical framework and methodology for interpreting the critique of classroom and science discourses is presented. To model and scaffold this ongoing debate, each chapter is followed by a "metalogue" in which the chapter authors and volume editors critique the issues traversed in the chapter by opening up the neatly argued issues. These "metalogues" challenge, extend, and deepen the arguments made. Central questions addressed include: *Why is a sociolinguistic interpretation essential in examining science education reform? *What are key similarities and differences between classroom and scientific communities? *How can the utility of common knowledge and existing classroom discourse be balanced toward alternative outcomes? *What curricular issues are associated with transforming classroom talk? *What other perspectives can assist in creating multiple access to science through redefining classroom discourse? Whether this volume improves readers' science teaching, assists their research, or helps them to better prepare tomorrow's science teachers, the goal is to engage them in considering the challenges faced by educators as they navigate the seas of reform and strive to improve science education for all.
Highly Efficient OLEDs: Materials Based on Thermally Activated Delayed Fluorescence
by Hartmut YersinThe essential resource that offers a comprehensive understanding of OLED optimizations Highly Efficient OLEDs. Materials Based on Thermally Activated Delayed Fluorescence (TADF) offers substantial information on the working principle of OLEDs and on new types of emitting materials (organic and inorganic). As the authors explain, OLEDs that use the Singlet-Harvesting mechanism based on the molecular property of TADF work according to a new exciton harvesting principle. Thus, low-cost emitter materials, such as Cu(I) or Ag(I) complexes as well as metal-free organic molecules, have the potential to replace high-cost rare metal complexes being currently applied in OLED technology. With contributions from an international panel of experts on the topic, the text shows how the application of new TADF materials allow for the development of efficient OLED displays and lighting systems. This new mechanism is the gateway to the third-generation of luminescent materials. This important resource: Offers a state-of-the-art compilation of the latest results in the dynamically developing field of OLED materials Is edited by a pioneer in the field of OLED material technology Contains a detailed application-oriented guide to new low-cost materials for displays and lighting Puts the focus on the emerging fields of OLED technology Written for materials scientists, solid state chemists, solid state physicists, and electronics engineers, Highly Efficient OLEDs. Materials Based on Thermally Activated Delayed Fluorescence offers a comprehensive resource to the latest advances of OLEDs based on new TADF materials.
India: Acquiring its Way to a Global Footprint
by Suseela YesudianAward winning case studies focusing on the growth of innovation in India.
Introduction to Thermal Cloaking: Theory and Analysis in Conduction and Convection
by Woon-Shing Yeung Ruey-Jen YangThis book introduces the fundamental concepts of thermal cloaking based on transformation theory and bilayer theory, under the conduction and convection heat transfer modes. It focuses on thermal cloaking with detailed explanations of the underlying theoretical bases leading to the primary thermal cloaking results in open literature, from an engineering perspective, and with practical application in mind. Also, the authors strive to present the materials with an emphasis on the related physical phenomena and interpretation, to the extent possible. Through this book, engineering students can grasp the fundamental ideas of thermal cloaking and the associated mathematics, thus being better able to initiate their own research and explore new ideas in thermal cloaking. While not intended to be a general reference in the vast field of thermal cloaking research, this book is a unique monograph addressing the theoretical and analytical aspects of thermal cloaking within the scope mentioned above. This book also contains many independent analytical solutions to thermal cloaking problems that are not available in open literature. It is suitable for a three-credit graduate or advanced undergraduate course in engineering science.
Depolarizing Collisions in Nonlinear Electrodynamics
by Igor V. Yevseyev Valery M. Yermachenko Vitaly V. SamartsevIn this book, the authors derive the theory of elastic depolarizing collisions and describe their importance in some nonlinear electromagnetic phenomena in gaseous media. The formation of photon echo and a description of its various types in gaseous media are then presented. The authors show that the characteristics of the corresponding signals depend essentially on elastic depolarizing collisions. They also consider the advantages of a new kind of photon echo spectroscopy: polarization photon echo-spectroscopy. A high-level, specialized treatment, Depolarizing Collisions in Nonlinear Electrodynamics will appeal to researchers and advanced graduates in nonlinear optics and quantum electronics.
Testing Software and Systems
by Nina Yevtushenko Ana Rosa Cavalli Hüsnü YenigünThis book constitutes the refereed proceedings of the 29th IFIP WG 6. 1 International Conference on Testing Software and Systems ICTSS 2017, held in St. Petersburg, Russia, in October 2017. The 18 full papers and 4 short papers presented were carefully reviewed and selected from 41 submissions. The topics of the volume cover model based testing; test derivation and monitoring; fault localization and system testing including real time systems.
Renewable and Sustainable Materials in Green Technology (SpringerBriefs in Applied Sciences and Technology)
by Mohd Firdaus Yhaya Husnul Azan Tajarudin Mardiana Idayu AhmadThis book discusses recent developments in renewable and sustainable materials from a green technology perspective and how these materials interact with the environment. It highlights the fundamental processes involved in the production of renewable and sustainable materials, including chemical and biological approaches as well as these materials’ potential application as green technological option. Written in a didactic style, it offers a guide and insights into renewable and sustainable materials. Each chapter provides in-depth technical information on the material’s theory and its applications. The book shows how new materials may help us solve human and environmental issues in the future and suggests where current research may lead.
Market-Driven Spectrum Sharing in Cognitive Radio
by Changyan Yi Jun CaiThis brief focuses on the current research on mechanism design for dynamic spectrum sharing in cognitive radio (CR) networks. Along with a review of CR architectures and characteristics, this brief presents the motivations, significances and unique challenges of implementing algorithmic mechanism design for encouraging both primary spectrum owners and secondary spectrum users to participate in dynamic spectrum sharing. The brief then focuses on recent advances in mechanism design in CR networks. With an emphasis on dealing with the uncertain spectrum availabilities, mechanisms based on spectrum recall, two-stage spectrum sharing and online spectrum allocation are introduced with the support of theoretic analyses and numerical illustrations. The brief concludes with a discussion of potential research directions and interests, which will motivate further studies on mechanism design for wireless communications. This brief is concise and approachable for researchers, professionals and advanced-level students in wireless communications and networks.
Hierarchical Sliding Mode Control for Under-actuated Cranes
by Jianqiang Yi Dianwei QianThis book reports on the latest developments in sliding mode overhead crane control, presenting novel research ideas and findings on sliding mode control (SMC), hierarchical SMC and compensator design-based hierarchical sliding mode. The results, which were previously scattered across various journals and conference proceedings, are now presented in a systematic and unified form. The book will be of interest to researchers, engineers and graduate students in control engineering and mechanical engineering who want to learn the methods and applications of SMC.
Econometric Analyses of International Housing Markets (Routledge Studies in International Real Estate)
by Rita Yi Man Li Kwong Wing ChauThis book explores how econometric modelling can be used to provide valuable insight into international housing markets. Initially describing the role of econometrics modelling in real estate market research and how it has developed in recent years, the book goes on to compare and contrast the impact of various macroeconomic factors on developed and developing housing markets. Explaining the similarities and differences in the impact of financial crises on housing markets around the world, the author's econometric analysis of housing markets across the world provides a broad and nuanced perspective on the impact of both international financial markets and local macro economy on housing markets. With discussion of countries such as China, Germany, UK, US and South Africa, the lessons learned will be of interest to scholars of Real Estate economics around the world.
The Design and Implementation of the RT-Thread Operating System
by Qiu Yi Xiong Puxiang Tianlong ZhuSince the release of V0.01 in 2006, to the present V4.0 version, RT-Thread has developed a reputation among developers for its open source strategy. RT-Thread has gained a large following among members of the embedded open source community in China with hundreds of thousands of enthusiasts. RT-Thread is widely used in energy, automotive, medical, consumer electronics, among other applications, making it a mature and stable open source embedded operating system. The purpose of RT-Thread RTOS Design and Implementation is to create an easy learning curve for mastering RT-Thread, so that more developers can participate in the development of RT-Thread and work together to create an open source, tiny, and beautiful Internet of Things operating system. The book’s first part introduces the RT-Thread kernel and starts with an overview of RT-Thread before covering thread management, clock management, inter-thread synchronization, inter-thread communication, memory management, and interrupt management. The second part begins with RT-Thread kernel porting and explains how to port RT-Thread to a hardware board to run it. The second part also introduces RT-Thread components and discusses the Env development environment, FinSH console, device management, and network framework. Additional topics covered include: The I/O device framework Virtual file systems Peripheral interfaces Devices including the PIN device, UART device, and ADC device, among others. Each chapter features code samples, as well as helpful tables and graphs, so you can practice as you learn as well as perform your own experiments.
Radio Protocols for LTE and LTE-Advanced
by SeungJune Yi SungDuck Chun YoungDae Lee SungJun Park SungHoon JungProvides a unique focus on radio protocols for LTE and LTE-Advanced (LTE-A) Giving readers a valuable understanding of LTE radio protocols, this book covers LTE (Long-Term Evolution) Layer 2/3 radio protocols as well as new features including LTE-Advanced. It is divided into two sections to differentiate between the two technologies’ characteristics. The authors systematically explain the design principles and functions of LTE radio protocols during the development of mobile handsets. The book also provides essential knowledge on the interaction between mobile networks and mobile handsets. Among the first publications based on the 3GPP R10 specifications, which introduces LTE-A Beginning with an overview of LTE, topics covered include: Idle Mode Procedure; Packet Data Convergence Protocol and Public Warning Systems Presents the LTE radio interface protocol layers in a readable manner, to enhance the material in the standards publications From an expert author team who have been directly working on the 3GPP standards It is targeted at professionals working or intending to work in the area and can also serve as supplementary reading material for students who need to know how theory on the most extensively used mobile radio interface today is put into practice
The Oil and Gas Service Industry in Asia
by Tan YiThis book investigates the business strategies chosen by oil and gas service companies operating in China, Singapore and Malaysia. It provides an analytical view of the reliability of strategic theoretical frameworks based on Western business practice but applied in a non-Western business environment like Asia.
Blockchain Foundations and Applications (SpringerBriefs in Applied Sciences and Technology)
by Xun Yi Xuechao Yang Andrei Kelarev Kwok Yan Lam Zahir TariThis monograph provides a comprehensive and rigorous exposition of the basic concepts and most important modern research results concerning blockchain and its applications. The book includes the required cryptographic fundamentals underpinning the blockchain technology, since understanding of the concepts of cryptography involved in the design of blockchain is necessary for mastering the security guarantees furnished by blockchain. It also contains an introduction to cryptographic primitives, and separate chapters on bitcoin, ethereum and smart contracts, public blockchain, private blockchain, cryptocurrencies, and blockchain applications.This volume is of great interest to active researchers who are keen to develop novel applications of blockchain in the field of their investigatio. Further, it is also beneficial for industry practitioners as well as undergraduate students in computing and information technology.
Human Factors in Aircraft Maintenance
by Demetris Yiannakides Charalampos SergiouThis book provides an in-depth analysis of human failure and its various forms and root causes. The analysis is developed through real aviation accidents and incidents and the deriving lessons learned. Features: Employs accumulated experience, and the scientific and research point of view, and recorded aviation accidents and incidents from the daily working environment Provides lessons learned and integrates the existing regulations into the human factors discipline Highlights the responsibility concerns and raises the accountability issues deriving from the engineers’ profession by concisely distinguishing human failure types Suggests a new approach in human factors training in order to meet current and future challenges imposed on aviation maintenance Offers a holistic approach in human factors aircraft maintenance Human Factors in Aircraft Maintenance is comprehensive, easy to read, and can be used as both a training and a reference guide for operators, regulators, auditors, researchers, academics, and aviation enthusiasts. It presents the opportunity for aircraft engineers, aviation safety officers, and psychologists to rethink their current training programs and examine the pros and cons of employing this new approach.
Food Safety = Behavior
by Frank YiannasThis book helps in Achieving food safety success which requires going beyond traditional training, testing, and inspectional approaches to managing risks. It requires a better understanding of the human dimensions of food safety. In the field of food safety today, much is documented about specific microbes, time/temperature processes, post-process contamination, and HACCP-things often called the hard sciences. There is not much published or discussed related to human behavior-often referred to as the "soft stuff. " However, looking at foodborne disease trends over the past few decades and published regulatory out-of-compliance rates of food safety risk factors, it's clear that the soft stuff is still the hard stuff. Despite the fact that thousands of employees have been trained in food safety around the world, millions have been spent globally on food safety research, and countless inspections and tests have been performed at home and abroad, food safety remains a significant public health challenge. Why is that? Because to improve food safety, we must realize that it's more than just food science; it's the behavioral sciences, too. In fact, simply put, food safety equals behavior. This is the fundamental principle of this book. If you are trying to improve the food safety performance of a retail or food service establishment, an organization with thousands of employees, or a local community, what you are really trying to do is change people's behavior. The ability to influence human behavior is well documented in the behavioral and social sciences. However, significant contributions to the scientific literature in the field of food safety are noticeably absent. This book will help advance the science by being the first significant collection of 50 proven behavioral science techniques, and be the first to show how these techniques can be applied to enhance employee compliance with desired food safety behaviors and make food safety the social norm in any organization.
Stem Cell-based Biosystems
by Yi-Chen Ethan Li I-Chi LeeStem cell science has emerged as a novel discipline in biomedical research over the past decade. With advancements in this field, stem cells have demonstrated versatile applications ranging from basic research to clinical case studies. Recognizing the demand for knowledge in stem cell applications, this book aims to provide comprehensive information on stem cell technology and its application in biosystems. It covers fundamental culture methods, advanced stem cell-based biosystems, and clinical case studies of stem cell therapy. This book is intended for individuals with an interest in stem cell science, offering valuable insights into this rapidly evolving field.
The Politics of Nuclear Energy in China
by Xu Yi-ChongExplores the history and challenges of nuclear energy development in China, across five main areas: politics, economics, environment, technology transfer and the nuclear fuel cycle. It emphasizes the political challenges in developing a set of long-term national strategies to ensure speedy, safe and secure nuclear energy development.
Innovation District Planning: Concept, Framework, Practice
by Tan Yigitcanlar Surabhi Pancholi Niusha Esmaeilpoorarabi Rosemary Adu-McVieThis book aims to fill the knowledge gap on how to plan, develop and manage innovation districts that are competitive in terms of both productivity and quality of living, justifying the massive investment put into place and at the same time doing both in a delicate and harmonious way.There is a need for smart urban land use that is wired with both hard infrastructures (e.g., telecommunication and transport) and soft infrastructures (e.g., diversity and tolerance). The reader learns this knowledge through conceptual expansions for key insights, frameworks for potential and performance assessment and best practices for global innovation districts. The authors begin innovation district planning with the role and effectiveness of planning a branding in the development of innovation districts. The next key topic of place making is recognised as a key strategy for supporting knowledge generation and innovation activities in the contemporary innovation districts. Another important topic is place quality where the reader learns to identify and classify indicators of place quality by studying global innovation districts best practices. The reader also expands their understanding on the classification of innovation districts based on their key characteristics through a methodological approach. The book concludes with district smartness studied through the socio-cultural role played by anchor universities in facilitating place making in innovation districts. Smart campuses, enabled by digital transformation opportunities in higher education, are seen as a miniature replica of smart cities and serve as living labs for smart technology.The book serves as a repository for scholars, researchers, postgraduate and undergraduate students as it communicates the complex innovation district phenomenon in an easy-to-digest form by providing both the big picture view and specifics of each component of that view.