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The End of My Addiction
by Olivier Ameisen"After years of battling uncontrollable addiction, I have achieved the supposedly impossible: complete freedom from craving."Dr. Olivier Ameisen was a brilliant cardiologist on the staff at one of America's top teaching hospitals and running his own successful practice when he developed a profound addiction to alcohol. He broke bones with no memory of falling; he nearly lost his kidneys; he almost died from massive seizures during acute withdrawal. He gave up his flourishing practice and, fearing for his life, immersed himself in Alcoholics Anonymous, rehab, therapy, and a variety of medications. Nothing worked.So he did the only thing he could: he took his treatment into his own hands. Searching for a cure for his deadly disease, he happened upon baclofen, a muscle relaxant that had been used safely for years as a treatment for various types of muscle spasticity, but had more recently shown promising results in studies with laboratory animals addicted to a wide variety of substances. Dr. Ameisen prescribed himself the drug and experimented with increasingly higher dosages until he finally reached a level high enough to leave him free of any craving for alcohol. That was more than five years ago. Alcoholism claims three hundred lives per day in the United States alone; one in four U.S. deaths is attributable to alcohol, tobacco, or illegal drugs. Baclofen, as prescribed under a doctor's care, could possibly free many addicts from tragic and debilitating illness. But as long as the medical and research establishments continue to ignore a cure for one of the most deadly diseases in the world, we won't be able to understand baclofen's full addiction-treatment potential.The End of My Addiction is both a memoir of Dr. Ameisen's own struggle and a groundbreaking call to action—an urgent plea for research that can rescue millions from the scourge of addiction and spare their loved ones the collateral damage of the disease.
Heal Thyself: A Doctor at the Peak of His Medical Career, Destroyed by Alcohol—and the Personal Miracle That Brought Him Back
by Olivier AmeisenHeal Thyself is the paperback edition of The End of My Addiction—a memoir of Ameisen's struggle and a call to action."[This book is] the story of the dazzling discovery of a cure that could soon be within reach of all . . . you must read this book." —David Servan-Schreiber, MD, PHD, author of Healing Without Freud or Prozac and AnticancerWhen Olivier Ameisen's book was first published, Barbara Fisher noted in The Boston Globe that "this is not your usual memoir of addiction, degradation, and redemption." His story is indeed unusual—not because he was a brilliant cardiologist who developed a profound addiction to alcohol, or because he tried numerous treatment options and none helped. His story was the story of millions of alcoholics—until he decided to take his treatment into his own hands.Searching for a cure for his deadly disease, he happened upon baclofen, a safe muscle relaxant that had recently shown promising results in studies with laboratory animals addicted to a wide variety of substances. Ameisen experimented with increasingly higher dosages until he reached a level that left him free of any craving for alcohol. That was more than six years ago.In the past year, a growing number of researchers and doctors have been inspired by Ameisen and begun prescribing baclofen and lobbying for wide-scale studies into how the drug works. Last spring, no less an authority than the leading medical journal Alcoholand Alcoholism endorsed the book. Hailing Dr. Ameisen as "a remarkable medical researcher," it summed up its assessment strongly and directly: "This book is to be recommended."
Pediatric Surgery: A Comprehensive Textbook for Africa
by Emmanuel A. Ameh Stephen W. Bickler Kokila Lakhoo Benedict C. Nwomeh Dan PoenaruThe second, fully updated edition of this book applies and contextualizes up-to-date information on pediatric surgery for low and middle-income countries (LMICs). The book is organized in general anatomic and thematic sections within pediatric surgery, such as urology, oncology, orthopedics and gastroenterology and includes chapters addressing the unique challenges and approaches for pediatric surgery in low-resource settings. Each chapter has dual authorship LMIC author providing context-specific insights and authors from high-income countries (HICs) contributing experience from well-resourced settings.Written in a reader-friendly format, this book has a uniform structure in each chapter, with introduction, demographics, etiology, pathophysiology, clinical presentations, investigations, management, outcome, prevention, ethics, evidence-based surgery and references. This comprehensive volume fills the gap between up-to-date pediatric surgical scholarship and knowledge developed and applied in HICs, and the practical needs of practitioners in low-resource settings. This is an indispensable guide for postgraduate surgical trainees in Africa and other LMICs as well as general surgeons practicing in Africa and other LMICs, who need to care surgically for children.
Take My Hand: The Caregiver’s Journey
by Tia Amdurer Chris Renaud-CogswellTake My Hand is a welcome, practical guide for the emotional journey of caregiving.The caregiver’s twisting and emotional journey is often bittersweet, combining feelings of exhaustion, reflection, love, frustration, delight, denial, connection, and loneliness. Just as they have taken on hand-holding for a loved one who needs multi-faceted support, many caregivers understandably feel overwhelmed and find themselves wishing for someone to guide them. Take My Hand is that resource. Written by Tia Amdurer, a Licensed Professional Counselor with a background in hospice, bereavement, grief, and loss, Take My Hand is structured into stand-alone chapters that can serve as a practical guide while navigating the different aspects of care for a loved one during the final years. Within each chapter are the witty, insightful, and heartfelt commentaries from Chris Renaud-Cogswell, penned as she took on the role of caregiver for her parents. Pages for note-taking and journaling are formatted to encourage self-reflection along the way.
Planning in Health Promotion Work: An Empowerment Model
by Roar AmdamCommunity development, planning and partnerships have become important terms in health promotion but, up until now, debate around these concepts have been discussed more in planning science than in public health literature. Roar Amdam draws on theories and new empirical evidence from local, regional and international planning and public health in order to develop a new model for health promotion: empowerment planning. Much health promotion planning has focused on top-down approaches, and while efforts to be participative are made, it is often without having a clear understanding of how community empowerment can be accommodated within health promotion programs. Amdam’s innovative concept combines top-down and bottom-up approaches to enable people to take more responsibility for their own health and for individual and collective capacity building. Planning in Health Promotion Work is suitable for all students and researchers of health promotion and health planning and development, whilst the numerous applied examples make it an invaluable resource for policymakers and practitioners working in public health.
PET/CT in Neuroendocrine Tumors
by Valentina Ambrosini Stefano FantiThis pocket book provides up-to-date descriptions of themost relevant features of neuroendocrine tumors (NETs) and the imagingmodalities currently available to assist specialists (clinicians, pathologists,radiologists, nuclear medicine physicians) in selecting optimal patientmanagement based on interdisciplinary collaboration. As the title indicates,the focus is particularly on PET/CT, with coverage of basic principles, theavailable radiopharmaceuticals, indications, typical and atypical appearances, normalvariants and artifacts, advantages, limitations, and pitfalls. In addition, succinctinformation is provided on the use of other imaging modalities, includingSPECT, CT, and MRI, and on pathology and treatment options. Imaging teachingcases are presented, and key points are highlighted throughout. The book ispublished as part of a series on hybrid imaging that isspecifically aimed at referring clinicians, nuclear medicine/radiology physicians,radiographers/technologists, and nurses who routinely work in nuclear medicineand participate in multidisciplinary meetings.
Controversies in Cardiology
by John A. Ambrose Alfredo E. RodríguezThis book will consider several clinical and interventional topics for which there is uncertainty, continued debate and/or no consensus based on current guidelines. While there are numerous guidelines in cardiology, new and on-going trials that address new drugs treatments and procedures raise many unanswered questions. Furthermore, most practicing cardiologist taking care of the patients are likely unable to digest all of these studies or guidelines and necessarily correctly apply them to their patients. If one considers in the guidelines the frequent use of Level C (consensus), there are many areas or situations where no trial exists. Also, when applying the results of a trial to an individual patient, there can be uncertainty of how this patient should be managed based on the present body of evidence.
The Brain and Pain: Breakthroughs in Neuroscience
by Richard AmbronPain is an inevitable part of existence, but severe debilitating or chronic pain is a pathological condition that diminishes the quality of life. The Brain and Pain explores the present and future of pain management, providing a comprehensive understanding based on the latest discoveries from many branches of neuroscience.Richard Ambron—the former director of a neuroscience lab that conducted leading research in this field—explains the science of how and why we feel pain. He describes how the nervous system and brain process information that leads to the experience of pain, detailing the cellular and molecular functions that are responsible for the initial perceptions of an injury. He discusses how pharmacological agents such as opiates affect the duration and intensity of pain. Ambron examines new evidence showing that discrete circuits in the brain modulate the experience of pain in response to a placebo, fear, anxiety, belief, or other circumstances, as well as how pain can be relieved by activating these circuits using mindfulness training and other nonpharmacological treatments. The book also evaluates the prospects of procedures such as deep brain stimulation and optogenetics.Current and thorough, The Brain and Pain will be invaluable for a range of people seeking to understand their options for treatment as well as students in neuroscience and medicine.
COVID Chronicles: A Comics Anthology (ISSN)
by Gene Ambaum Julio Anta Ned Barnett Ken Best Armond Boudreaux Eiri BrownIn 2020, the COVID-19 pandemic brought the world to its knees. When we weren’t sheltering in place, we were advised to wear masks, wash our hands, and practice social distancing. We watched in horror as medical personnel worked around the clock to care for the sick and dying. Businesses were shuttered, travel stopped, workers were furloughed, and markets dropped. And people continued to die.Amid all this uncertainty, writers and artists from around the world continued to create comics, commenting directly on how individuals, societies, governments, and markets reacted to the worldwide crisis. COVID Chronicles: A Comics Anthology collects more than sixty such short comics from a diverse set of creators, including indie powerhouses, mainstream artists, Ignatz and Eisner Award winners, and media cartoonists. In narrative styles ranging from realistic to fantastic, they tell stories about adjusting to working from home, homeschooling their kids, missing birthdays and weddings, and being afraid just to leave the house. They probe the failures of government leaders and the social safety net. They dig into the racial bias and systemic inequities that this pandemic helped bring to light. We see what it’s like to get the virus and live to tell about it, or to stand by helplessly as a loved one passes.At times heartbreaking and at others hopeful and humorous, these comics express the anger, anxiety, fear, and bewilderment we feel in the era of COVID-19. Above all, they highlight the power of art and community to help us make sense of a world in crisis, reminding us that we are truly all in this together.The comics in this collection have been generously donated by their creators. A portion of the the proceeds from the sale of this volume are being donated by the publisher to the Book Industry Charitable Foundation (Binc) in support of comics shops, bookstores, and their employees who have been adversely affected by the pandemic.
Forever Ours: Real Stories of Immortality and Living from a Forensic Pathologist
by Janis Amatuzio[From the Book Jacket] As a physician, forensic pathologist, and coroner for several Minnesota counties, I have had the extraordinary privilege of caring for families and their loved ones when death comes suddenly, unexpectedly, or traumatically. My job is to speak for the dead, to solve the mystery of "What happened?" However, I have occasionally been faced with mysteries I cannot solve or explain. These experiences always baffle me, partly because as a scientist I seek to reach a reasonable degree of medical certainty, a rational explanation. But I have come to realize that for some experiences there is no explanation, just a deep knowing that I have encountered the Divine. - JANIS AMATUZIO, MD
Therapeutic Strategies in Veterinary Oncology
by Nicole Amato Jacob Cawley Steven Dow Joelle Fenger Andi Flory Ira Gordon Kayla Harding Kelvin Kow Cheryl London Nicola Mason Arata Matsuyama Jonathan Mochel Anthony Mutsaers Henrik Rönnberg Wesley WiersonThis book is a comprehensive resource for veterinary oncologists and trainees, covering therapeutic strategies used in the treatment of veterinary patients. In the setting of a rapidly changing field like oncology, this timely text focuses on mechanisms of action and biological rationale rather than current specific clinical recommendations, allowing current and future clinicians to adapt treatment approaches as our understanding of the biology of cancer evolves. With each chapter written by experts in their field, this book provides informative figures that convey this biological understanding and rationale of therapy. It starts from the mechanisms of treatment as we currently understand them, covering radiation therapy, chemotherapy, immunotherapy, targeted therapy, and many more. Dispensing vital, detailed and practical information about the different therapeutic strategies available, this book is a vital resource for practicing veterinarians, while also providing students of veterinary oncology with a better understanding of the key differences between different treatment strategies.
Inguinal Hernia: Pathophysiology and Genesis of the Disease
by Giuseppe AmatoThis book aims at filling a gap in relation to the pathophysiology of the inguinal region and the genesis of groin protrusions. While inguinal hernia is a widespread disease and hernia repair accounts for the most frequently performed surgical procedure, these two aspects have been unsatisfactorily investigated, so that to date there is no shared hypothesis on how visceral protrusion through inguinal barrier occur. Exact knowledge on the pathogenesis is fundamental for adequately managing a disease, otherwise all curative approaches would not be evidence-based, but merely empirically identified and with uncertain outcomes carried out. Moreover, in absence of pathogenetic certainty, formulating guidelines simply results in an unjustified methodology harbinger of polemics and controversies. Previous studies concerning the pathogenesis of inguinal protrusions were mainly focused on the detection of biochemical changes, mostly related to collagen chains, metalloproteinase and similar elements. Nevertheless, despite decades of researches, a sure relationship between these ultrastructural modifications and visceral protrusion has not been proven. On the contrary, over the years very few investigations dealt with evidencing eventual modifications in the tissue structures of the herniated groin. An extensive research finalized to ascertain in patients and in cadavers structural changes of the tissue elements composing the groin was therefore carried out by the author and his researchers team. The findings of these studies resulted to be very useful for definitely evidencing the etiology of inguinal hernia disease. Overall, the proposed book scrutinizes and widens all emerging aspects related to pathogenesis, histology, physiology, surgical and functional anatomy of the inguinal area affected by hernia protrusion. It intends to be a reference guide to surgeons willing to better understand the structural modifications occurring in patients affected by this disease with the aim of improving treatment results.
My Beautiful Disaster: My Brain Injury, My Gift, My Life
by Derek AmatoDerek Amato's reflections in My Beautiful Disaster provide rare insight into what people with extraordinary gifts see, think, feel and do; pose questions about the potential to tap into previously undetected abilities and spotlight the 'silent epidemic' of head trauma. His experiences also make vivid some the challenges faced by those living with autism and other neurological disorders and hint at the possibility we all have more in common than we think. Readers enchanted by autistic savant, Daniel Tammet's eloquent Born On A Blue Day, will welcome another multi-layered, first person account of what is to live with a remarkable condition. Uniquely, having spent his life as a "neurotypical" Amato's tale relates the before and after of 'the gift'; his voice at times resonating with incredulity at what has happened and what the eventual cost may be.
An Athletic Trainers’ Guide to Sports Nutrition
by Damon AmatoAn Athletic Trainer’s Guide to Sports Nutrition fills the void of a subject area that is underrepresented in current athletic trainer curriculums despite its importance in the field. Damon Amato has created a text that can be easily read and understood by health care professionals yet is in-depth enough to create a solid understanding of how the body works, and easy enough to then pass on the information to athletes to help them eat ideally based on their specific sport, goal, and situation. Giving a physiology background is necessary to lay the foundation for understanding why certain recommendations in the text are given; however, only the necessary details are included to focus on what is pertinent for athletic trainers to understand while advising athletes.Some topics covered inside include: Basics of human nutrition Disordered eating and eating disorders in athletes Supplements Eating optimally for injury recovery Nutrient timing Special situations An Athletic Trainer’s Guide to Sports Nutrition gives athletic training clinicians and students the information and tools necessary to aid athletes in maintaining peak performance in nutrition, and fills the void left in the current athletic training curriculum.
How Does That Make You Feel?: True Confessions from Both Sides of the Therapy Couch
by Sherry AmatensteinHow Does That Make You Feel? obliterates the boundaries between the shrink and the one being shrunk with unabashedly candid writers breaking confidentiality and telling all about their experiences in therapy. This revelatory, no-punches-pulled book brings to light both sides of the "relationship” between therapist and client-a bond that can feel pure and profound, even if it is, at times, illusory. Contributors include an array of essayists, authors, TV/film writers and therapists, including Patti Davis, Beverly Donofrio, Royal Young, Molly Peacock, Susan Shapiro, Charlie Rubin, Estelle Erasmus, and Dennis Palumbo. Full list of contributors: Sherry Amatenstein Laura Bogart Martha Crawford Patti Davis Megan Devine Beverly Donofrio Janice Eidus Estelle Erasmus Juli Fraga Nina Gaby Mindy Greenstein Jenine Holmes Diane Josefowicz Jean Kim Amy Klein Binnie Klein Anna March Allison McCarthy Kurt Nemes Dennis Palumbo Molly Peacock Pamela Rafalow Grossman Charlie Rubin Jonathan Schiff Barbara Schoichet Adam Sexton Susan Shapiro Beth Sloan Eve Tate Kate Walter Priscilla Warner Linda Yellin Royal Young Jessica Zucker
Health IT and EHRs: Principles and Practice
by Margret K. AmatayakulThis sixth edition is being renamed Health IT and EHRs as a result of the expanded scope of the technology needed for all health information collection and use. The sixth edition is also focused more on serving as a textbook in addition to serving as a reference work for readers who work in any health setting, whether a healthcare provider organization, vendor, health plan, or policy-maker. The book introduces the full scope of health IT in chronological fashion, covering the information systems development life cycle, strategic planning, goal setting workflow and process mapping, change management, vendor selection, project management, and implementation, training, and ongoing maintenance of EHR and other health IT systems. It also addresses the essential elements of data infrastructure, information technology, privacy and security, and interoperability for all forms of health IT. Finally, there is considerable expansion in chapters covering techniques to achieve value with health IT in various acute care, ambulatory care, and specialty care settings as well as for consumer health IT, enterprise content and record management as an EHR bridge technology, revenue cycle management, and population health. Those familiar with the fifth edition of Electronic Health Records: A Practical Guide for Professionals and Organizations will find that some of the chapters have been moved around, consolidated, or expanded in the sixth edition. Two chapters have been added, on revenue cycle management and population health, given expanded interest in integrating information on clinical, administrative or financial, and social determinants of health.
Process Improvement with Electronic Health Records: A Stepwise Approach to Workflow and Process Management
by Margret AmatayakulAlthough physicians and hospitals are receiving incentives to use electronic health records (EHRs), there is little emphasis on workflow and process improvement by providers or vendors. As a result, many healthcare organizations end up with incomplete product specifications and poor adoption rates.Process Improvement with Electronic Health Records:
Process Improvement with Electronic Health Records: A Stepwise Approach to Workflow and Process Management
by Margret AmatayakulAlthough physicians and hospitals are receiving incentives to use electronic health records (EHRs), there is little emphasis on workflow and process improvement by providers or vendors. As a result, many healthcare organizations end up with incomplete product specifications and poor adoption rates.Process Improvement with Electronic Health Records: A Stepwise Approach to Workflow and Process Management walks you through a ten-step approach for applying workflow and process management principles regardless of what stage your organization is in its EHR journey. Introducing workflow and process mapping as essential elements in healthcare improvement, it includes detailed guidance, helpful tools, and case studies in each chapter. It also: Compares EHR workflow and process management to other continuous quality improvement methodologies Highlights the processes that need to be addressed in EHR workflow and process redesign Describes the level of detail necessary for workflow and process mapping to be effective Explains how to create change agents and offers time-tested change management tools The book describes the process for getting stakeholders to create, document, and validate new workflows and processes. Using case studies to illustrate the unique requirements of health information technology (HIT) and EHR acquisition, this reference provides you with simple yet powerful tools along with step-by-step guidance for the effective use of workflow and process mapping within healthcare.
Acupuncture and the Chakra Energy System
by John Amaro John R. Cross Nadia EllisAcupuncture and the chakra energy system have both become increasingly mainstream in the West, but rarely have the two approaches been joined into one practice. Acupuncture and the Chakra Energy System: Treating the Cause of Disease does just that. By comparing the traditional approaches of Chinese medicine and modern Western acupuncture with the chakra energy system of Ayurvedic philosophy, author John Cross offers clinically proven strategies for treating the causes of conditions, not just the symptoms. The book describes the seven major and twenty-one minor chakras in detail and explains how each is related to the body's aura, meridians, Key points, endocrine glands, autonomic nervous system, and varying symptomatology. Focusing on how to use the chakras in the treatment of chronic physical and emotional conditions--osteo-arthritis, rheumatoid arthritis, low back pain with sciatica, insomnia, hypertension, depression, menopausal symptoms, and frozen shoulder, among others--Cross's clear, in-depth explanations make his techniques easy for anyone to follow. Including appendices on how to use the chakras with copper and zinc needles and biomagnets, as well as which types of patients respond to such treatments, Acupuncture and the Chakra Energy System is a well-rounded guide for acupuncturists and other practitioners as well as interested students.
Exploration and Analysis of DNA Microarray and Other High-Dimensional Data
by Dhammika Amaratunga Ziv Shkedy Javier CabreraExploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition provides comprehensive coverage of recent advancements in microarray data analysis. A cutting-edge guide, the Second Edition demonstrates various methodologies for analyzing data in biomedical research and offers an overview of the modern techniques used in microarray technology to study patterns of gene activity. The new edition answers the need for an efficient outline of all phases of this revolutionary analytical technique, from preprocessing to the analysis stage. Utilizing research and experience from highly-qualified authors in fields of data analysis, Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition features: A new chapter on the interpretation of findings that includes a discussion of signatures and material on gene set analysis, including network analysisNew topics of coverage including ABC clustering, biclustering, partial least squares, penalized methods, ensemble methods, and enriched ensemble methodsUpdated exercises to deepen knowledge of the presented material and provide readers with resources for further study The book is an ideal reference for scientists in biomedical and genomics research fields who analyze DNA microarrays and protein array data, as well as statisticians and bioinformatics practitioners. Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition is also a useful text for graduate-level courses on statistics, computational biology, and bioinformatics.
Veterinary Clinical Skills Manual
by Aruna Amarasinghe Stacy Anderson Fiona Handyside Brown David B Church Nichola Coombes Kate English John Fishwick M.L.A.N.R.Deepani Desiree Herrick Caroline Hoy Karen Rachael Humm Imogen Johns Desiree Karlsson Tierney Kinnison Nicola Jayne Kulendra Alison J Langridge Rachel Lumbis Panagiotis Mantis Stephen May N. Odontsetseg Hilary A Orpet Bat Otgontugs Matthew Pead Chris Seymour Dr Ayona Silva-Fletcher Isobel Vincent Victoria Watts Renate Weller Julie Williamson Catherine Wager Alison YoungDown-to-earth and intensely practical, this book and video package provides step-by-step guidance on the essential clinical skills required by veterinary students before they face clinical situations encountered in the real world of the busy veterinary professional. - Contains step by step illustrations and photographs, complemented by videos of clinical procedures which can be viewed on your desktop, smartphone or tablet. - Covers the essential key skills that veterinary students need to know. - Details a whole range of techniques, from surgical, anaesthesia and laboratory through to everyday essential and diagnostic skills, in both farm and companion animals. - Describes in-depth the use of simulators in learning key skills. - Provides advice on preparing for OSCEs and practical exams. This book is the go-to manual for an essential grounding in key veterinary clinical skills for all students and educators of veterinary medicine and animal husbandry.
Madness and Social Change: Autobiography of the Brazilian Psychiatric Reform
by Paulo AmaranteIn this book, the history of the Brazilian Psychiatric Reform is told by one of its main protagonists. In the early 1980s, there were about 80 thousand people admitted to psychiatric hospitals in Brazil, with average lengths of hospital stay of approximately 25 years. The psychiatric reform process that took place in the country was responsible for closing more than 60 thousand beds in mental asylums, most of them characterized by conditions of violence and abandonment.The Brazilian Psychiatric Reform was inspired by the psychosocial care model introduced by psychiatrist Franco Basaglia in Italy and was marked by the broad participation of social movements, such as the anti-asylum movement and other human rights movements. This process gave rise to a model of mental health care based on open-door territorial mental health services, guided by the principle of treatment in liberty, in addition to other strategies of deinstitutionalization. More than a proposal to restructure or modernize the mental health care model, the objective of the Brazilian Psychiatric Reform was the construction of a new social place for the diverse and singular subjective experience of madness. By intending to produce new imaginaries, new social representations and new meanings for these experiences, the Brazilian Psychiatric Reform led to one of the larger experiences of deinstitutionalization in the world and to the large scale implementation of a new model of mental health care in which the old asylum-centric paradigm was replaced by a new democratic psychosocial care model.
Advanced Neuroradiology Cases
by Amaral Lázaro Luís Faria do Bag Asim K. Gonçalves Fabrício Guimarães Hanagandi Prasad B. Byan-Parker Suzanne Prasad B. Byan-ParkerFeaturing atypical cases and focusing on advanced imaging techniques, this book presents a compilation of unusual CNS pathologies with characteristic imaging findings. The aim is to aid the speedy diagnosis of otherwise rarely encountered clinical conditions and improve patient care. Presented as more than 130 real cases with extensive imaging description and step-by-step guidelines on how to diagnose individual pathologies, each scenario is backed by the most up-to-date literature available. The cases include some of the most recently described clinical conditions. The case-based format and description of each clinical journey encourages readers to engage with the diagnostic process and facilitates self-study. This book is for any radiologist who practices neuroradiology, neuroradiology fellows, neuroimaging fellows, practicing neurologist and neurology residents.
Reviews of Physiology, Biochemistry and Pharmacology 157
by S. G. Amara E. Bamberg T. Gudermann S. C. Hebert R. Jahn W. J. Lederer R. Lill A. Miyajima S. OffermannsThis volume presents a neural network architecture for the prediction of conditional probability densities - which is vital when carrying out universal approximation on variables which are either strongly skewed or multimodal. Two alternative approaches are discussed: the GM network, in which all parameters are adapted in the training scheme, and the GM-RVFL model which draws on the random functional link net approach. Points of particular interest are: - it examines the modification to standard approaches needed for conditional probability prediction; - it provides the first real-world test results for recent theoretical findings about the relationship between generalisation performance of committees and the over-flexibility of their members; This volume will be of interest to all researchers, practitioners and postgraduate / advanced undergraduate students working on applications of neural networks - especially those related to finance and pattern recognition.
Reviews of Physiology, Biochemistry and Pharmacology 156
by S. G. Amara E. Bamberg S. Grinstein S. C. Hebert R. Jahn W. J. Lederer R. Lill A. Miyajima H. Murer S. Offermanns G. Schultz M. SchweigerH. Wegele, L. M ller, and J. Buchner: Hsp70 and Hsp90 A Relay Team for Protein Folding R. Sch lein: The Early Stages of the Intracellular Transport of Membrane Proteins: Clinical and Pharmacological Implications L. Schild: The Epithelial Sodium Channel: From Molecule to Disease