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Advances in Hemophilia Treatment: From Genetics to Joint Health
by E. Carlos Rodríguez-MerchánThis book offers a comprehensive and state of the art overview of hemophilia management by reviewing all most recent advances and cutting edge information in this fast evolving field. As hemophilia patients are often affected by joint problems it also provides clear guidance on the surgical treatment of musculo-skeletal manifestations. The first part is devoted to the disease’s pathophysiology (differentiating hemophilia A and B), genetics, pharmacotherapy – including replacement and non-replacement therapy – and gene therapy, as well as quality of life issues – also related to hemophilia carriers. The second part is then focused on joint problems, ranging from joint health assessment and pain control to surgical treatment of acute hemarthrosis and hemophilic arthropathy, i.e. radiosynovectomy, total joint arthroplasty and arthroscopic joint debridement.Written by experts drawn from leading institutions involved in treatment of hemophilia and related joint problems, this book offers a valuable resource to hematologists, orthopedic surgeons, rehabilitation physicians, radiologists, and pharmacy researchers.
Advances in Healthcare Informatics and Analytics (Annals of Information Systems #19)
by Ashish Gupta Vimla L. Patel Robert A. GreenesThis important new volume presents recent research in healthcare information technology and analytics. Individual chapters look at such issues as the impact of technology failure on electronic prescribing behavior in primary care; attitudes toward electronic health records; a latent growth modeling approach to understanding lifestyle decisions based on patient historical data; designing an integrated surgical care delivery system using axiomatic design and petri net modeling; and failure in a dynamic decision environment, particularly in treating patients with a chronic disease. Other chapters look at such topics as the impact of information technology integration in integrated delivery systems; operations and supply chain control for inventory management in a health system pharmacy; decision-theoretic assistants based on contextual gesture recognition; evaluating emergency response medical information systems; clinical decision support in critical care; virtual worlds in healthcare; and natural language processing for understanding contraceptive use at the VA.
Advances in Health Care Organization Theory
by Patrick D. Shay Stephen S. MickExplore the evolution of organization theory in the health caresector Advances in Health Care Organization Theory, 2nd Edition,introduces students in health administration to the fields oforganization theory and organizational behavior and theirapplication to the management of health care organizations. Thebook explores the major health care developments over the pastdecade and demonstrates the contribution of organization theory toa deeper understanding of the changes in the delivery system,including the historic passage of the Patient Protection andAffordable Care Act of 2010. Taking both a micro and macro view,editors Stephen S. Mick and Patrick D. Shay, collaborate with aroster of contributing experts to compile a comprehensive volumethat covers the latest in organization theory. Topics include:Institutional and neo-institutional theoryPatient-centered practices and organizational culturechangeDesign and implementation of patient-centered care managementteamsHospital-based clusters as new organizational structuresApplication of social network theory to health care
Advances in H∞ Control Theory: Switched, Delayed, and Biological Systems (Lecture Notes in Control and Information Sciences #481)
by Eli Gershon Uri ShakedAdvances in H∞ Control Theory is concerned with state-of-the-art developments in three areas:the extended treatment of mostly deterministic switched systems with dwell-time;the control of retarded stochastic state-multiplicative noisy systems; anda new approach to the control of biochemical systems, exemplified by the threonine synthesis and glycolytic pathways.Following an introduction and extensive literature survey, each of these major topics is the subject of an individual part of the book.The first two parts of the book contain several practical examples taken from various fields of control engineering including aircraft control, robot manipulation and process control. These examples are taken from the fields of deterministic switched systems and state-multiplicative noisy systems.The text is rounded out with short appendices covering mathematical fundamentals: σ-algebra and the input-output method for retarded systems.Advances in H∞ Control Theory is written for engineers engaged in control systems research and development, for applied mathematicians interested in systems and control and for graduate students specializing in stochastic control.
Advances in Growth Curve Models: Topics from the Indian Statistical Institute (Springer Proceedings in Mathematics & Statistics #46)
by Ratan DasguptaAdvances in Growth Curve Models: Topics from the Indian Statistical Institute is developed from the Indian Statistical Institute's A National Conference on Growth Curve Models. This conference took place between March 28-30, 2012 in Giridih, Jharkhand, India. Jharkhand is a tribal area. Advances in Growth Curve Models: Topics from the Indian Statistical Institute shares the work of researchers in growth models used in multiple fields. A growth curve is an empirical model of the evolution of a quantity over time. Case studies and theoretical findings, important applications in everything from health care to population projection, form the basis of this volume. Growth curves in longitudinal studies are widely used in many disciplines including: Biology, Population studies, Economics, Biological Sciences, SQC, Sociology, Nano-biotechnology, and Fluid mechanics. Some included reports are research topics that have just been developed, whereas others present advances in existing literature. Both included tools and techniques will assist students and researchers in their future work. Also included is a discussion of future applications of growth curve models.
Advances in Geriatric Dermatology
by Anne Lynn S. ChangThis concise, easy-to-read book summarizes the current clinical evidence and basic science relating to aging and the skin, assisting the clinician in addressing skin problems in older dermatologic patients. Each chapter focuses on a particular area in which new knowledge has rapidly emerged over the past 5 years, ensuring that the book is completely up-to-date. Recent insights into aging skin from basic and translational science are first discussed, covering the underlying genetics and the potential role of topical agents and procedures in reversing the aging process. Evidence-based prescribing in older patients is then explained, and the evidence relating to treatments for psoriasis, reviewed. Further chapters in Geriatric Dermatology address non-surgical treatment options for basal cell carcinoma, the increase in and management of sexually transmitted diseases in older dermatology patients, and cutaneous signs of elder mistreatment. Case vignettes and informative illustrations assist the reader in quickly grasping the connection between an age-related process and its clinical impact. Geriatric Dermatology is written for dermatologists, research scientists with translational interest, geriatricians, and gerontologists.
Advances in Functional Micro-/Nanoimaging Probes (Engineering Materials)
by Zhe LiuThis book highlights the latest advances in functional micro/nano imaging probes and their applications for biomedical imaging and therapy. Given the rapid emergence of transdisciplinary research and applications in materials, chemical probes and translational medicine in recent years, scientists in these areas are expected to keep up to date on the latest technologies and advances to promote comprehensive innovations. Addressing this need, the book presents recently introduced features, emerging techniques, and new strategies, complemented by detailed illustrations. Covering the status quo and offering an outlook on the future, it benefits all readers with an interest in functional materials, especially micro/nano imaging materials for biomedical imaging applications, providing them with both vital updates and inspiration for their own research.
Advances in Fetal and Neonatal Physiology: Proceedings of the Center for Perinatal Biology 40th Anniversary Symposium (Advances in Experimental Medicine and Biology #814)
by Lubo Zhang Charles A. DucsayTo celebrate the Center for Perinatal Biology's 40th Anniversary, an illustrious group gathered at Loma Linda University in February 2013. That gathering of experts and this volume of the proceedings are a tribute to the founder of the Center, Lawrence D. Longo, M. D. These chapters present contributions from individuals who in some way or another were influenced by Dr. Longo. Covering a wide range of topics, and illustrating the diversity of thinking and scientific interests, these proceedings address basic science through to clinical problems in the developmental programming of health and disease.
Advances in Exercise and Health for People With Mobility Limitations
by David HollarThe purpose of this book is to provide public health, disability, and rehabilitation professionals and practitioners evidence-based science with respect to health disparities faced by people with disabilities, especially people with mobility limitations; alternative methods of rehabilitation and exercise science for this population; assistive device technology; and, improved access to health care, employment, and social participation.According to the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR), approximately 57 million Americans live with a disability. Disability severity and types vary considerably, such that each individual with a disability faces unique physical, social, and environmental barriers in order to enjoy quality of life and full participation in society. A large research literature shows that people with disabilities face substantial employment and health disparities compared to people without disabilities. People with mobility limitations often experience secondary conditions to compound their primary disability. Hollar (2013) and Hollar and Lewis (2015) showed that people with mobility limitations were significantly more likely to experience obesity and lack of access to physical exercise. Other studies have shown that access to proper physical examination facilities and equipment remain a substantial barrier in many clinics and hospitals despite the enactment of the Americans with Disabilities Act 25 years ago. Research on alternative exercise programs and new assistive device technologies offers promise to improve physical functioning and exercise for people with mobility limitations. Furthermore, increased focus on biopsychosocial over traditional medical models for disability will help policymakers and the public to recognize the complex, contextual issues (e.g., personal, social, environmental) that affect the lives of people with disabilities.Readership includes public health practitioners and educators, disability and rehabilitation researchers, clinicians and sports medicine practitioners, and disability advocates. There have been general handbooks on disability, but advances in technology and alternative exercise programs, as well as novel disability health programs, are dispersed in the research literature. This book will help to highlight these programs for health policy experts, especially given the high health and social disparities experienced by this population.
Advances in Esthetic Implant Dentistry
by Abdelsalam ElaskaryA comprehensive and highly illustrated reference on current topics in esthetic dental implant therapy Advances in Esthetic Implant Dentistry provides a current, comprehensive overview of esthetic implant therapy. Offering innovative step-by-step protocols for surgical techniques and case studies, the book presents practical, clinically oriented guidance firmly anchored in solid scientific research. A companion website provides videos of clinical procedures and follow-up case studies. The book emphasizes the physiology of labial plate of bone and its influence to the overall fate of implant placement in fresh extraction sites, including several cutting-edge techniques to restore and treat deficient labial plate of bone. A novel chapter offers a solid protocol to diagnose, categorize, and treat implant-related gingival recession predictably. Highlights novel esthetic protocols in dental implantology, applying the latest advances in clinical techniques to real-world dentistry Follows up on treatment outcomes, presenting results up to seven years later Provides reliable, evidence-based bone regenerative methods Illustrates procedures step by step, with more than 2500 clinical photographs Features a companion website with videos of clinical procedures and follow-up case studies Advances in Esthetic Implant Dentistry is an indispensable clinical companion for practitioners and students of periodontics, prosthodontics, oral and maxillofacial surgery, and general dentistry, bringing the reader new horizons in esthetic dentistry.
Advances in Equine Upper Respiratory Surgery
by Jan HawkinsAdvances in Equine Upper Respiratory Surgery is a comprehensive, up-to-date reference on surgical techniques in the upper respiratory tract in the horse, presenting theory and background as well as detailed procedures information. Part of the Advances in Veterinary Surgery series copublished with the ACVS Foundation, the book covers the most common upper respiratory diseases, with in-depth information on laryngeal hemiplegia and dorsal displacement of the soft palate. Providing a complete resource, the book reflects the current state of the art, offering a significant update on disorders of the nasal septum, nasal passage, paranasal sinuses, hard and soft palate, epiglottis, arytenoids, guttural pouch, and trachea in the horse.The book includes 200 images illustrating key points of each surgical procedure. Potential complications and expectation management are discussed alongside the technique information. Advances in Equine Upper Respiratory Surgery is a useful reference for those in clinical practice and surgical residents.
Advances in Equine Laparoscopy
by Claude A. RaglePart of the Advances in Veterinary Surgery series copublished with the ACVS Foundation and Wiley-Blackwell, Advances in Equine Laparoscopy presents a state-of-the-art reference on laparoscopic skills and procedures in the horse. Chapters are written by the leading experts in the field, and each section includes a practical review of the published literature. Encompassing instrumentation, basic principles, and specific techniques, Advances in Equine Laparoscopy offers an up-to-date, reliable resource for comprehensive information about equine laparoscopy.This current, well-referenced text begins with a section on the fundamentals of laparoscopy, then moves into sections on the clinical application of laparoscopic techniques in the standing or recumbent horse. A companion website offers eight video clips demonstrating selected procedures at www.wiley.com/go/ragle. Advances in Equine Laparoscopy is an invaluable guide for equine surgical specialists and equine clinicians interested in laparoscopic techniques.
Advances in environmental chemistry and toxicology of mercury
by Guangliang Liu Yong Cai Nelson O'DriscollThe book that looks at mercury's impact on the planet today Recent research by the EPA has concluded that one in six women of childbearing age have unsafe levels of mercury in their bodies, which puts 630,000 newborn babies each year at risk of neurological impairment. Mercury poses severe risks to the health of animals and ecosystems around the world, and this book provides the essential information that anyone interested in environmental sciences should know about the fundamentals of the entire mercury cycle. Comprised of four parts that present an overview of mercury in the environment, mercury transformations, transport, and bioaccumulation and toxicology, each chapter of Environmental Chemistry and Toxicology of Mercury includes the basic concepts of the targeted subject, a critical review of that subject, and the future research needs. This book explains the environmental behavior and toxicological effects of mercury on humans and other organisms, and provides a baseline for what is known and what uncertainties remain in respect to mercury cycling. The chapters focus on the fundamental science underlying the environmental chemistry and fate of mercury. This work will be invaluable to a wide range of policy experts, environmental scientists, and other people requiring a comprehensive source for the state of the science in this field.
Advances in Environmental Biotechnology
by Raman Kumar Anil Kumar Sharma Sarabjeet Singh AhluwaliaThe book aims to provide a comprehensive view of advanced environmental approaches for wastewater treatment, heavy metal removal, pesticide degradation, dye removal, waste management, microbial transformation of environmental contaminants etc. With advancements in the area of Environmental Biotechnology, researchers are looking for the new opportunities to improve quality standards and environment. Recent technologies have given impetus to the possibility of using renewable raw materials as a potential source of energy. Cost intensive and eco-friendly technology for producing high quality products and efficient ways to recycle waste to minimize environmental pollution is the need of hour. The use of bioremediation technologies through microbial communities is another viable option to remediate environmental pollutants, such as heavy metals, pesticides and dyes etc. Since physico-chemical technologies employed in the past have many potential drawbacks including higher cost, and lower sustainability. So there is need of efficient biotechnological alternatives to overcome increasing environmental pollution. Hence, there is a need for environmental friendly technologies that can reduce the pollutants causing adverse hazards on humans and surrounding environment.
Advances in Endoscopy in Inflammatory Bowel Disease
by Toshifumi Hibi Tadakazu Hisamatsu Taku KobayashiRecent Advances and Atlas of Endoscopy in Inflammatory Bowel Disease summarizes the recent progress made in endoscopy, an essential tool for the diagnosis and management of IBD. It goes on to provide an introduction of state-of-the-art endoscopic techniques, as well as an atlas of high-quality endoscopic images of IBD and related diseases. Among others, endoscopy is one of the clinical fields in which Asian countries are leading the way in the management of gastrointestinal disorders. As the number of patients with IBD is dramatically increasing in Asia, quality of patient care has been significantly improved. With diagnosis of intestinal Behcet, simple ulcers, and intestinal tuberculosis, which are unique to the Asian countries, this book offers the ideal standard textbook for IBD endoscopy in all Asian counties, while the superior quality of images also makes it a valuable resource for practitioners around the globe. This book will significantly help all physicians, endoscopists and researchers working on GI endoscopy, especially those focusing on IBD, to improve their knowledge of IBD endoscopy.
Advances in Electromagnetic Fields in Living Systems: Volume 5, Health Effects of Cell Phone Radiation (Advances in Electromagnetic Fields in Living Systems #5)
by James C. LinHealth Effects of Cell Phone Radiation will offer a concentrated and up-to-date overview on the effects of radio frequencies on human tissue. While significant advances are being made on many fronts, ranging in frequency from quasi-static to the optical regime, a special emphasis of this volume is on current understanding of biological interactions of cellular mobile communication radiation. The use of cell-phones has experienced phenomenal growth - some estimate that there will be more than 3.5 billion users of these wireless devices by the end of 2010, worldwide. The widespread impact of these new wireless technologies has raised concerns about the safety of human exposure to radio-frequency (RF) energy emitted by these telecommunication devices. A better understanding of the biological effects of RF electromagnetic field is needed to safeguard against possible harm to the general population. Fortunately in recent years there has been a resurgence of research interest in achieving a quantitative understanding of the relationships between the biological effects of RF radiation and the physical variables that may cause them. A significant number of results have and are beginning to appear in the literature. This volume reviews and assesses the biological effects of exposure to electromagnetic fields from wireless communication technology.
Advances in Elder Abuse Research: Practice, Legislation and Policy (International Perspectives on Aging #24)
by Amanda PhelanThis book provides an insight into advances in elder abuse in the areas of research, policy, practice and legislation. It provides readers with a broad understanding of the topic and considers the progress in elder abuse knowledge. The book explores the nexus of ageism and elder abuse, describes key social policies and their legislative manifestation, covers major policies and programs related to elder abuse, defines elder sexual abuse and much more. It offers the reader a comprehensive insight into new perspectives and approaches to both understanding and responding to elder abuse. As such it will be an asset to academics, students, healthcare practitioners, policy makers and the general public.
Advances in DNA Repair in Cancer Therapy (Cancer Drug Discovery and Development #72)
by Moulay Alaoui-Jamali Raquel Aloyz Lawrence PanasciA comprehensive review of the recent developments in DNA repair research that have potential for translational applications. The book explains in detail the various biological mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK. The book captures-for both cancer researchers and oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies.
Advances in Digital Human Modeling: Proceedings of the 8th International Digital Human Modeling Symposium, 4-6 September 2023, Antwerp, Belgium (Lecture Notes in Networks and Systems #744)
by Sofia Scataglini Gregor Harih Wim Saeys Steven TruijenThis book reports on advances in human modeling techniques, covering cutting-edge algorithms and their practical implementation in health and medicine, automotive, clothing, virtual reality simulations, robotics, and assistive technologies. Gathering the proceedings of the 8th International Digital Human Modeling Symposium, held on September 4-6, 2023, in Antwerp, Belgium, it offers a timely snapshot on interdisciplinary, applied research, at the interface between computer science, ergonomics, engineering, design, health and technologies.
Advances in Diagnosis and Management of Ovarian Cancer
by Samir A. FarghalyOvarian Cancer: Advances in Diagnosis and Management presents unique international perspectives on this devastating disease. While ovarian cancer has mainly been considered a disease of the Western hemisphere, this book moves beyond our conventional understanding and embraces knowledge from around the world. The focus is on recent advances in diagnosis, including genetic screening, and improvements and expanded choices in management, such as the optimization of chemotherapeutic agents, gene therapy, and the latest laparoscopic and robotic surgical techniques. Further chapters address psychosocial and quality-of-life issues. This book is an excellent resource on the international state-of-the-art in the diagnosis and management of ovarian cancer and is aimed at oncologists, gynecologists, and fellows.
Advances in Diagnosis and Management of Ovarian Cancer
by Samir A. FarghalyThis new edition features updated information on all aspects of the diagnosis and management of ovarian cancer. Embracing knowledge from around the world, this multidisciplinary book discusses current approaches to ovarian cancer that have helped stabilize the rate of both incidences and fatality for the disease. The chapters focus on genetic screening and advances in management, including the optimization of chemotherapeutic agents, gene therapy, and the latest laparoscopic and robotic surgical techniques. Further chapters address psychosocial and quality-of-life issues as well. The book is a must-have resource for wide range of practitioners who care for patients with ovarian cancer and researchers who study the disease.
Advances in Diagnosis and Management of Cutaneous Adverse Drug Reactions: Current and Future Trends
by Neil H. Shear Roni P. Dodiuk-GadThis resource guides prescribers, pharmacists, and regulators with an update on the recent expansion of basic and clinical knowledge that forms a framework for understanding cutaneous reactions. This understanding will lead, in turn, to better outcomes and decisions in treatment and management, both in the clinic and in the life cycle of drug development.The skin is a common target for adverse drug events and even mild rashes can be part of life-threatening syndromes. Patients and practitioners often face important decisions about therapy after a drug eruption, including treatment, cross-reactivity with future pharmaceuticals, genetic considerations and dealing with long-term sequelae after a reaction. An international team of experts and leaders in the field share their story and insights into the scientific details and relevant clinical context.
Advances in Diabetes Research and Management
by Rana NoorThis book discusses the latest research in the pathophysiology, diagnosis, and screening of diabetes and its management. It reviews novel technologies for early diagnosis and highlights the molecular mechanisms of microvascular and macrovascular complications of diabetes 2 mellitus. The book covers the applications of nanotechnology in diagnostics, monitoring, and treatment of diabetes mellitus. The chapter also presents the latest developments in differentiating pancreatic cells from PSCs and illustrates the challenges of their therapeutic application in treating diabetes. The book also explores the prospective medicinal plants comprising either plant extract or isolated bioactive phytoconstituents bearing anti-diabetic potential, which has been reported in several in vitro, in vivo, or clinical studies. It further examines the major mechanisms involved in cardiovascular complications among type 2 diabetes mellitus individuals and discusses the various pharmacological interventions and agents developed to delay cardiovascular events and thereby the quality and duration of the patients. Towards the end, the book summarizes the potential impact of ketogenic diets on diabetic patients, and the role of genetic vulnerability in diabetic nephropathy. As such, this book is a valuable source for students, researchers, and practitioners working in glucose metabolism, diabetes, and human health.
Advances in Dental Implantology using Nanomaterials and Allied Technology Applications
by Ramesh S. Chaughule Rajesh DashaputraAs the name suggests this book discusses how nanotechnology has influenced the provision of implant treatment from surgery to prosthetic reconstruction and post treatment biological complications. This book is a sequel to the earlier book “Dental Applications of Nanotechnology” published by Springer. It aims to present both the nanotechnology and allied research along with the clinical concepts of almost every different aspect of implantology in one volume. These two fraternities promote the translation of the research ideas and product development into fruitful practicalities. The first section covers nanobiomaterials in implant applications, in bone regeneration, prosthetic rehabilitation, to control biofilm and peri-implantitis, bone grafting and tissue engineering. The second section explores applications of such new technologies in the field of implantology that gives this book a unique feature by bringing science and technology into clinical application. It covers implant stability, peri-implantitis, lasers, CAD/CAM technology, impressions, 3D printing, reconstruction with bone grafts and zygomatic implants. Comprehensive coverage includes both simple and complicated clinical cases, with practical guidance on how to apply the latest research, diagnostic tools, treatment planning, implant designs, materials, and techniques to provide superior patient outcomes. The book is well written and structured making it easy for experienced clinicians and those new to dental implantology as well as students, researchers, scientists and faculties of dental universities
Advances in Degradation Modeling: Applications to Reliability, Survival Analysis, and Finance (Statistics for Industry and Technology)
by Nikolaos Limnios Waltraud Kahle N. Balakrishnan Catherine Huber-Carol M. S. NikulinThis volume is a collection of invited chapters covering recent advances in accelerated life testing and degradation models. The book covers a wide range of applications to areas such as reliability, quality control, the health sciences, economics and finance. It is an excellent reference for researchers and practitioners in applied probability and statistics, industrial statistics, the health sciences, quality control, economics, and finance.