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Animal Magnetism: My Life with Creatures Great and Small
by Rita Mae BrownA heartfelt memoir from bestselling author Rita Mae Brown about the animals who have loved, endured, and taught her, and about her bottomless love for them.
Animal Magnetism: The unputdownable romance you've been searching for! (Animal Magnetism)
by Jill ShalvisThe first in the sexy, heartwarming Animal Magnetism series from the New York Times bestselling author of the Cedar Ridge and Lucky Harbor series. Fans of Bella Andre, Robyn Carr and Rachel Gibson will adore these romances with Jill's irresistible combination of humour and romance.Sunshine, Idaho, is a small, sunny town - the perfect home for man and beast. Well, maybe not for man, as pilot-for-hire Brady Miller discovers when his truck is rear-ended by what appears to be Noah's Ark. As the co-owner of the town's only kennel, Lilah Young has good reason to be distracted behind the wheel - there are puppies, a piglet and a duck in her Jeep. Still, she doesn't find it hard to focus on the sexy, gorgeous stranger she's collided with. Brady is just passing through, but there's something about Lilah and her menagerie that makes the temptation of staying in Sunshine one that's difficult to resist...Want more sexy, fun romance? Return to Sunshine, Idaho for more of the captivating Animal Magnetism series, visit spellbinding Lucky Harbor or take a trip to Cedar Ridge's unforgettable Colorado Mountains in Jill's other bestselling series.
Animal Maltreatment Evaluation Basics for Mental Health Practitioners, Students, and Educators
by Lynett Henderson Metzger Laura Meyer Lavita NadkarniThis book provides a brief introduction to the growing field of animal maltreatment evaluation and treatment, with a special emphasis on clinical training from a forensic psychology perspective. Geared toward mental health practitioners, students, and educators, this broad overview focuses on foundational legal concepts, applications in clinical and psycholegal settings, and emerging perspectives on effective evaluation and treatment. The authors provide practical guidance around “real world” scenarios through the use of clinical case vignettes, highlighting the complexities and need for culturally- and psychologically-informed care in these cases. Key topics include forensic animal maltreatment evaluations (or FAMEs); implications for best practices; challenges for providers, trainees, and supervisors; and future directions for the field.
The Animal Manifesto: Six Reasons for Expanding Our Compassion Footprint
by Marc BekoffIn this inspirational call to action, Marc Bekoff, the world’s leading expert on animal emotions, gently shows that improving our treatment of animals is a matter of rethinking our many daily decisions and “expanding our compassion footprint.” He demonstrates that animals experience a rich range of emotions, including empathy and compassion, and that they clearly know right from wrong. Driven by moral imperatives and pressing environmental realities, Bekoff offers six compelling reasons for changing the way we treat animals — whether they’re in factory farms, labs, circuses, or our vanishing wilderness. The result is a well-researched, informative guide that will change animal and human lives for the better.
Animal Matters: Diary of an Inner City Vet
by Charlotte Rea'Heartwarming and hilarious' Telegraph'With as many horrifying stories as heart-warming ones, this is a fascinating look at the year in the life of a vet at a London animal charity hospital. There are some proper belly laughs as well as some insights that will truly stick with you.' - Alexandra Heminsley, GraziaAn unusual 'dalmation', a TV star with cancer, an out of control budgie. Charlotte Rea has seen them all, and more. Animal Matters is Charlotte's diary of real-life cases written during a one year of her work as a veterinary surgeon in a 24-hour inner-city London animal charity. The diary reveals the reality of working as a vet, how it can be both emotional and amusing, one minute you can be consoling an owner on the loss of their much-loved pet, the next trying to catch an escaped budgie. Charlotte mixes deeply sad moments with amusing and unimaginable ones along with more detailed accounts and reflections back on her training and the experiences she has come up against over the decade since she graduated. Throughout the book you will get to know both the animals and the people and how close the bond between us can be. Charlotte also discusses contemporary issues in veterinary medicine such as animal euthanasia, RSPCA welfare cases, mental health issues within the veterinary profession, ethical concerns around pedigree dog breeding and the laws on dangerous dogs. Animal Matters is a moving and heartwarming book about the unconditional love between animals and humans.
Animal Matters: Diary of an Inner City Vet
by Charlotte Rea'Heartwarming and hilarious' TelegraphAn unusual 'dalmation', a TV star with cancer, an out of control budgie. Charlotte Rea has seen them all, and more. Animal Matters is Charlotte's diary of real-life cases written during a one year of her work as a veterinary surgeon in a 24-hour inner-city London animal charity. The diary reveals the reality of working as a vet, how it can be both emotional and amusing, one minute you can be consoling an owner on the loss of their much-loved pet, the next trying to catch an escaped budgie. Charlotte mixes deeply sad moments with amusing and unimaginable ones along with more detailed accounts and reflections back on her training and the experiences she has come up against over the decade since she graduated. Throughout the book you will get to know both the animals and the people and how close the bond between us can be. Charlotte also discusses contemporary issues in veterinary medicine such as animal euthanasia, RSPCA welfare cases, mental health issues within the veterinary profession, ethical concerns around pedigree dog breeding and the laws on dangerous dogs. Animal Matters is a moving and heartwarming book about the unconditional love between animals and humans.
Animal Matters: Diary of an Inner City Vet
by Charlotte ReaAnimals bond people and transcend class, financial and cultural barriers, pets matter to people more than anything, but what happens to those people who can't afford pet insurance or vet's bills.Animal Matters is a diary of real-life cases written during a year of Charlotte's career working as a veterinary surgeon in a 24-hour inner-city London animal charity hospital. The book provides readers with a revealing, honest, emotional experience, with deeply sad moments followed by amusing and unimaginable ones. Charlotte writes both short amusing diary entries along with more detailed accounts and reflections back on her training and the experiences and difficulties she has come up against over the decade since she graduated. Throughout the book you will get to know both the animals and the people and how close the bond between us can be. Charlotte also discusses contemporary issues in veterinary medicine such as animal euthanasia, RSPCA welfare cases, mental health issues within the veterinary profession, ethical concerns around pedigree dog breeding and the laws on dangerous dogs. Animal Matters is a moving and heartwarming book about the unconditional love between animals and humans, and how deep the bond can be.(P)2019 Hodder & Stoughton Limited
Animal Messengers: An A-Z Guide to Signs and Omens in the Natural World
by Regula MeyerAn animal-by-animal guide that reveals the meaning behind each encounter we have with animals • Provides sophisticated psychological insight into encounters with more than 150 animals, birds, reptiles, insects, and aquatic life • Explores how animals reflect our inner world, drawing our attention to inner turmoil, relationship issues, spiritual growth, and the deepest needs of the soul • Explains how the meaning of each encounter depends on whether the animal was hunting, fleeing, hiding, or acting indifferent when sighted We each feel connections to animals in our own way. Some of us have pets. Others admire animals in the wild. Because the outer world often reflects our internal states and animals are highly sensitive to our energies, each encounter with an animal signals something about our inner world and innermost concerns. The spontaneous, surprising contacts are the telling ones: a sparrow landing next to you, a fox darting across the road, or a bee alighting on your hand. However, even regular encounters with our pets can draw attention to our inner world and what needs to be thought over and grappled with, from psychic turmoil and relationship issues to spiritual growth and the deepest needs of the soul. Providing sophisticated psychological insight into encounters with more than 150 animals, birds, reptiles, insects, and aquatic life, Regula Meyer explores the messages each animal provides for us on a personal level when we encounter them. She explains how the meaning of each encounter depends on whether the animal was hunting, fleeing, hiding, or acting indifferent when sighted. For example, a fleeing animal is prompting you to pursue a subject consciously, while a hiding animal tells you to patiently observe something and draw insights from it. The author shows how animal encounters in the wild cause us to contemplate the present moment and inspire the flow of our perceptions, leading us to meditate on important concerns we may be ignoring or unaware of. Pets and other animals we see every day act as intensifiers of the energy for which they stand. With this animal-by-animal guide, you can discover the deep meaning behind your encounters with animals and the messages they bring as oracles of our souls.
Animal Migration
by Jeanie Mebane Bernd HeinrichWhy do wildebeests travel 1,800 miles each year? How do salmon find their way back to the stream where they hatched? Migrating animals move in some unique ways. Discover the amazing ways migrating animals get around.
The Animal Mind a Text-Book of Comparative Psychology
by Margaret Floy Washburn"The Animal Mind: A Text-Book of Comparative Psychology" by Margaret Floy Washburn is a seminal work that offers an in-depth exploration of animal behavior and cognition, bridging the gap between psychology and zoology. As one of the first comprehensive textbooks in the field of comparative psychology, Washburn's groundbreaking work provides valuable insights into the mental processes of various animal species, laying the foundation for future research in animal cognition.Washburn, a pioneering psychologist and the first woman to earn a Ph.D. in psychology in the United States, meticulously examines the sensory experiences, instincts, emotions, and intelligence of animals. Drawing on extensive research and observational studies, she presents a thorough analysis of how animals perceive the world, make decisions, and exhibit behaviors that parallel human psychological processes."The Animal Mind" covers a wide range of topics, including perception, learning, memory, and problem-solving abilities in animals. Washburn's clear and engaging writing style makes complex concepts accessible, while her rigorous scientific approach ensures the reliability and depth of the information presented. Each chapter delves into specific aspects of animal psychology, supported by detailed examples and comparative analyses across different species.Washburn's work is notable for its balanced perspective, considering both experimental data and anecdotal evidence to provide a holistic view of animal minds. She emphasizes the importance of understanding animal behavior not just for its own sake but also for the insights it offers into human psychology and the evolutionary continuity of mental processes."The Animal Mind" is an essential resource for students, researchers, and anyone interested in the study of animal behavior and cognition. Margaret Floy Washburn's pioneering contributions continue to influence the field of comparative psychology, making this textbook a timeless and invaluable reference for understanding the complexities of animal minds and their remarkable similarities to human thought and behavior.
Animal Minds: What Are They Thinking? (Orca Wild #12)
by Dana L. ChurchA deep dive into the minds of animals and how they think. Wouldn't it be amazing to see inside the mind of a lion, a gorilla, an octopus or even a bee? In Animal Minds: What Are They Thinking?, author Dana L. Church looks at how scientists are doing just that. Their research shows that a wide variety of species have unique personalities, impressive memories, counting abilities, and incredible problem-solving skills. Meet the scientists who study the minds of animals, discover the similarities and differences between the minds of different species and learn how they compare to our own. From dolphins to dung beetles, tigers to turkey vultures, Animal Minds shows that we are only beginning to scratch the surface when it comes to revealing the amazing inner worlds of the thousands of different creatures with whom we share this planet. The epub edition of this title is fully accessible.
Animal Minds: Beyond Cognition to Consciousness
by Donald R. GriffinIn Animal Minds, Donald R. Griffin takes us on a guided tour of the recent explosion of scientific research on animal mentality. Are animals consciously aware of anything, or are they merely living machines, incapable of conscious thoughts or emotional feelings? How can we tell? Such questions have long fascinated Griffin, who has been a pioneer at the forefront of research in animal cognition for decades, and is recognized as one of the leading behavioral ecologists of the twentieth century. With this new edition of his classic book, which he has completely revised and updated, Griffin moves beyond considerations of animal cognition to argue that scientists can and should investigate questions of animal consciousness. Using examples from studies of species ranging from chimpanzees and dolphins to birds and honeybees, he demonstrates how communication among animals can serve as a "window" into what animals think and feel, just as human speech and nonverbal communication tell us most of what we know about the thoughts and feelings of other people. Even when they don't communicate about it, animals respond with sometimes surprising versatility to new situations for which neither their genes nor their previous experiences have prepared them, and Griffin discusses what these behaviors can tell us about animal minds. He also reviews the latest research in cognitive neuroscience, which has revealed startling similarities in the neural mechanisms underlying brain functioning in both humans and other animals. Finally, in four chapters greatly expanded for this edition, Griffin considers the latest scientific research on animal consciousness, pro and con, and explores its profound philosophical and ethical implications.
Animal Minds: Beyond Cognition to Consciousness
by Donald R. GriffinIn Animal Minds, Donald R. Griffin takes us on a guided tour of the recent explosion of scientific research on animal mentality. Are animals consciously aware of anything, or are they merely living machines, incapable of conscious thoughts or emotional feelings? How can we tell? Such questions have long fascinated Griffin, who has been a pioneer at the forefront of research in animal cognition for decades, and is recognized as one of the leading behavioral ecologists of the twentieth century. With this new edition of his classic book, which he has completely revised and updated, Griffin moves beyond considerations of animal cognition to argue that scientists can and should investigate questions of animal consciousness. Using examples from studies of species ranging from chimpanzees and dolphins to birds and honeybees, he demonstrates how communication among animals can serve as a "window" into what animals think and feel, just as human speech and nonverbal communication tell us most of what we know about the thoughts and feelings of other people. Even when they don't communicate about it, animals respond with sometimes surprising versatility to new situations for which neither their genes nor their previous experiences have prepared them, and Griffin discusses what these behaviors can tell us about animal minds. He also reviews the latest research in cognitive neuroscience, which has revealed startling similarities in the neural mechanisms underlying brain functioning in both humans and other animals. Finally, in four chapters greatly expanded for this edition, Griffin considers the latest scientific research on animal consciousness, pro and con, and explores its profound philosophical and ethical implications.
Animal Models for Assessing Countermeasures to Bioterrorism Agents
by Committee on Animal Models for Assessing Countermeasures to Bioterrorism AgentsThe Transformational Medical Technologies (TMT) has been a unique component of the U. S. Department of Defense (DoD) medical biodefense efforts since 2006. Its mission is to advance countermeasure research and development in support of the broader goal of the DoD to protect warfighters from emerging infectious diseases and future genetically engineered biological weapons. The TMT, using advanced science and technology approaches, focused on the development of roadspectrum countermeasures that target common host and pathogen pathways or enhance the host's immune response. Many of these pathogens are lethal or cause such debilitating diseases in humans that it is ethically inappropriate to test the efficacy of these countermeasures in human volunteers. In lieu of human participants, these products may be tested in animals and approved for human use under the provisions of the Food and Drug Administration (FDA)'s 2002 Animal Rule. The reliance on animal models for the development and licensure of medical countermeasures against biothreats is challenging for a number of reasons. The ad hoc Committee on Animal Models for Assessing Countermeasures to Bioterrorism Agents prepared a consensus report that would address the challenges stemming from developing and testing medical countermeasures against biothreat agents in animal models. "Animal Models for Assessing Countermeasures to Bioterrorism Agents" evaluates how well the existing TMT-employed or candidate animal models reflect the pathophysiology, clinical picture, and treatment of human disease as related to the agents of interest. The report addresses the process and/or feasibility of developing new animal models for critical biodefense research, placing emphasis on the need for a robust and expeditious validation process in terms of the FDA's Animal Rule. The report also evaluates alternatives to the use of animal models based on the premise of the Three Rs.
Animal Models for Retinal Diseases (Neuromethods #46)
by Iok-Hou Pang Abbot F. ClarkAffecting over a hundred million individuals worldwide, retinal diseases are among the leading causes of irreversible visual impairment and blindness, and appropriate study models, especially animal models, are essential to furthering our understanding of the etiology, pathology, and progression of these endemic diseases. In Animal Models for Retinal Diseases, recognized experts in the field highlight valuable techniques as well as animal models for the prominent retinal diseases in order to aid in the evaluation, development, and improvement of therapeutic strategies. Beginning with an overview of the morphology of the retina, visual behavior, and genetics and genomics approaches for retinal research, the book continues by covering animal models for the research of specific human retinal diseases, e.g., retinal degeneration, age-related macular degeneration, retinopathy of prematurity, diabetic retinopathy, glaucoma, retinal ischemia, and retinal inflammation. As a volume in the successful Neuromethods series, the chapters provide authoritative reviews of the most commonly used approaches in the field. Vital and easy to use, Animal Models for Retinal Diseases serves to support the important future research of ocular investigators, ophthalmologists, and neuroscientists currently delving into this fascinating field of study.
Animal Models in Cardiovascular Research (Developments In Cardiovascular Medicine Ser. #Vol. 153)
by David GrossInterest in the humane and scientifically justifiable use of research animals has intensified since the publication of the 2nd edition of Animal Models in Cardiovascular Research. This completely revised and updated edition will provide information essential to any researcher interested in using animal models for cardiovascular research, or any research which requires normal cardiovascular function. The format and presentation will be changed to make the text more easy to read and use: (1) This edition is in outline format, for ease and utility. (2) The opening chapter includes more information on the cardiovascular effects of post-operative analgesia and will address the recognition of pain behavior in species commonly used in research settings, particularly rats and mice. (3) New edition includes reference material more useful to researchers using transgenic and naturally occurring animal models to dissect these mechanisms.
Animal Models in Medical Mycology
by Makoto MiyajiThe prevalence of antibiotics, corticosteroids, and anticancer or immunosuppressive drugs and the progress of the medical treatments after World War II have saved the lives of many patients attacked by serious diseases and have contributed to the prolongation of the average life span of a human being. However, there still remain some problems to be solved. One of them is that of compromised hosts, which will be treated in this book.
Animal Models in Research: Principles and Practice
by Harikrishnan Vijayakumar Sreelatha Satish Patel Perumal NagarajanThis book describes the development of animal models widely used in biomedical research using step-wise instructions and photographs. Showcasing a wide range of species from zebra fishes, birds, rodents, rabbits, dogs, and pigs, the book includes detailed methodology on how to work with these species and to develop various models. The animal models in neurology including stroke, Alzheimer’s disease, Parkinson’s disease, and Schizophrenia; Animal models in cancer research, sleep disorders, and cardiovascular diseases are described to meet the understanding of researchers who plan to replicate these models in their laboratories. In depth detailing on the development of targeted gene knockouts and transgenics, implantation models that are used in toxicology studies, and pharmacokinetic studies in pigs and dogs are a highlight. Further, the book describes pharmacologic, chemically induced, surgically induced, microbiologically induced, infectious models, models for neurobehavioral studies, oncology research, and pain research. The book has dedicated sections on anesthesia and analgesia and teaches procedures like venous cut-downs and cannulations in pigs and dogs, and endotracheal intubation, mechanical ventilation and thoracotomy in rodents and will serve as a self-training tool. Concepts in the field of animal model development are explained using examples. Sample size selection, study design, and statistical evaluation of experiments involving laboratory animals are explained to enable young researchers to practically understand the nuances. This book will be a valuable tool for academicians, students, scientists, and veterinarians and will benefit equally who are new to the field and who are already working with laboratory animals.
Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments, Volume 1 (Springer Protocols Handbooks)
by John H. Zhang Zao C. Xu Jun Chen Xiao-Ming XuThe successful previous volume on this topic provided a detailed benchwork manual for the most commonly used animal models of acute neurological injuries including cerebral ischemia, hemorrhage, vasospasm, and traumatic brain and spinal cord injuries. <P><P> Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments aims to collect chapters on assessing these disorders from cells and molecules to behavior and imaging. These comprehensive assessments are the key for understanding disease mechanisms as well as developing novel therapeutic strategies to ameliorate or even prevent damages to the nervous system. <P><P> Volume 1 examines general assessments in morphology, physiology, biochemistry and molecular biology, neurobehavior, and neuroimaging, as well as extensive sections on subarachnoid hemorrhage, cerebral vasospasm, and intracerebral hemorrhage. Designed to provide both expert guidance and step-by-step procedures, chapters serve to increase understanding in what, why, when, where, and how a particular assessment is used.<P><P> Accessible and essential, Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments will be useful for trainees or beginners in their assessments of acute neurological injuries, for experienced scientists from other research fields who are interested in either switching fields or exploring new opportunities, and for established scientists within the field who wish to employ new assessments.
Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments, Volume 2 (Springer Protocols Handbooks)
by John H. Zhang Zao C. Xu Jun Chen Xiao-Ming XuThe successful previous volume on this topic provided a detailed benchwork manual for the most commonly used animal models of acute neurological injuries including cerebral ischemia, hemorrhage, vasospasm, and traumatic brain and spinal cord injuries. Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments aims to collect chapters on assessing these disorders from cells and molecules to behavior and imaging. These comprehensive assessments are the key for understanding disease mechanisms as well as developing novel therapeutic strategies to ameliorate or even prevent damages to the nervous system. Volume 2 examines global cerebral ischemia, focal cerebral ischemia, and neonatal hypoxia-ischemia, as well as intensive sections covering traumatic brain injury and spinal cord injury. Designed to provide both expert guidance and step-by-step procedures, chapters serve to increase understanding in what, why, when, where, and how a particular assessment is used. Accessible and essential, Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments will be useful for trainees or beginners in their assessments of acute neurological injuries, for experienced scientists from other research fields who are interested in either switching fields or exploring new opportunities, and for established scientists within the field who wish to employ new assessments.
Animal Models of Behavior Genetics (Advances in Behavior Genetics)
by Jonathan C. Gewirtz Yong-Kyu KimThis stimulating analysis reviews the broad potential of animal models to foster a deeper understanding of human pathology, strengthen connections between genetic and behavioral studies, and develop more effective treatments for mental disorders. Widely-studied and lesser-used species are examined in models that capture features along the continuum of normative and pathological behavior. The models highlight genetic causes of core features, or endophenotypes, of developmental, internalizing, and externalizing disorders, as well as dementia. Expert contributors address questions ranging from how suitable species are chosen for study to the costs and benefits of using inbred versus outbred strains, and the effects of housing environment on subject animals. Larger issues addressed include how to evaluate the applicability of animal behavioral models to the human condition and how these models can harness emerging molecular technologies to further our understanding of the genetic basis of mental illness. Included in the coverage: Mating and fighting in Drosophila. Attachment and social bonding. Impulsivity in rodents and humans. Animal models of cognitive decline. Animal models of social cognition. Future directions for animal models in behavioral genetics. A detailed map of where this evolving field is headed, Animal Models of Behavior Genetics shows geneticists, molecular biologists, and cognitive neuroscientists paths beyond established concepts toward a more knowledgeable and collaborative future.
Animal Models of Behavioral Analysis (Neuromethods #50)
by Jacob RaberDespite the difficulty in comparing clinic-based human tests with animal model testing, there is still great value in pursuing translational approaches, as tests and treatment strategies might be developed to improve brain function in humans suffering from neurological conditions and knowledge obtained from human behavioral studies can be used to further improve the animal models of behavioral analysis. In Animal Models of Behavioral Analysis, expert neuroscientists focus on approaches to translate and compare behavioral tests used in animals with those used in humans not only to increase our understanding of brain function across species but also to provide objective performance measures and bridge the gap between behavioral alterations in humans with cognitive disorders and the correlating animal models of these conditions. Written in the Neuromethods series format, the chapters provide authoritative reviews of many commonly used approaches in the field today. Provocative and cutting-edge, Animal Models of Behavioral Analysis seeks to aid researchers in further developing these vital techniques in an effort to advance studies in both the clinic and the laboratory.
Animal Models of Brain Tumors (Neuromethods #77)
by Alfredo Martínez Ricardo Martínez MurilloAlthough the available models, whether at the cellular, tissue, or animal level, do not exactly represent the biology of human brain tumors, animal models can offer significant insights into these tumors, providing a better understanding of biological mechanisms underlying tumor generation, growth, angiogenesis, invasion, and metastasis. Animal Models of Brain Tumors brings together developments and discoveries in "in vivo" experimental tumor research that have provided advances in our understanding of the cellular and molecular mechanisms involved in the generation, progression, and clinical outcome of brain neoplasms. Broken into convenient sections, this thorough volume includes topics such as animal model insights into human brain neoplasms, the cellular, molecular, and genetic basis of brain tumors, therapies in the treatment of malignant glioma, as well as imaging technologies in animal tumor models, i.e. measuring brain tumor growth and metabolism. Written for the popular Neuromethods series, chapters include the kind of detailed description and implementation advice that is essential for achieving successful results. Authoritative and cutting-edge, Animal Models of Brain Tumors provides the key methods needed to validate, compare, and contrast the animal model with its proposed human counterpart and further the understanding of our own serious ailments.
Animal Models of Dementia (Neuromethods #48)
by Peter Paul De Deyn Debby Van DamWith an ever-increasing elderly population and the resultant rising levels of dementia-related disorders, preclinical research based on animal models is pivotal to our knowledge of underlying molecular mechanisms and drug discovery aiming at the development of therapeutic strategies alleviating or preventing the neurological devastation. In Animal Models of Dementia, expert researchers provide contributions that stress the importance of extensively validated animal models in drug discovery and development in order to predict clinical activity. Beginning with general aspects of animal modeling, related ethical issues, and essential methodological considerations, the highly detailed volume then continues with various levels of model validation, including pathological, behavioral, neurochemical, pharmacological, and imaging aspects, followed by sections focused on specific disorders, such as Alzheimer's disease, Parkinson's disease, metachromatic leukodystrophy and adrenoleukodystrophy, amyotrophic lateral sclerosis, frontotemporal dementia as well as vascular dementia and more. As a volume in the renowned Neuromethods series, this book offers a detailed, yet accessible, overview of currently available animal models in the field of dementia research, and touches, as well, upon more general areas linked to the development and use of animal models. Comprehensive and efficient, Animal Models of Dementia will significantly aid both experienced animal researchers as well as investigators on the verge of beginning animal model-based dementia research.
Animal Models of Diabetes: Methods and Protocols (Methods in Molecular Biology #2128)
by Aileen J. F. KingThis volume discusses a variety of animal models of diabetes, as well as describes techniques used to study end-points when using these models. The chapters in this book cover topics such as important considerations when working with mouse models of diabetes, highlighting factors that new investigators may not be aware of and some potential pitfalls in experimental outcomes; main characteristics of some commonly used animal models of diabetes research, ranging from mice to primates; animal models used to study specific aspects of beta-cell biology; and a focus on techniques used to assess blood glucose homeostasis, insulin action, and islet function in vivo and ex vivo. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Animal Models of Diabetes: Methods and Protocols is a valuable resource that will help diabetes researchers design and carry out in vivo studies that will best suit their experimental questions and needs.