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The CRISPR-Cas9 Quarrel
by Richard G. Hamermesh Matthew PrebleIn mid-2016, the Broad Institute and the University of California, Berkeley were in the middle of a contentious patent dispute over which entity controlled a breakthrough gene editing technology called CRISPR-Cas9. With CRISPR-Cas9, scientists might soon be able to cure previously incurable genetic diseases such as sickle cell anemia and cystic fibrosis, among many others. The dispute had escalated to the point where the U.S. Patent and Trademark Office (USPTO) declared a patent interference and began a process to determine the intellectual property's (IP) rightful owner. The USPTO's decision would not only have serious commercial implications-the technology would be immensely important to biotechnology firms looking to develop gene therapy products, and was therefore sure to generate strong revenues for whichever entity owned the IP-but would also essentially award scientific credit for this technology and thus impact the reputations of the scientists on both sides who had worked so hard to discover the tool. This case touches upon a number of other key issues too: the ethical implications of gene editing; the state of IP and licensing in the biotechnology industry; the impact of lawsuits on developing new technologies and companies; and who should own platform technologies built, at least in part, by the research of multiple parties and government funding.
Criterion-referenced Test Development
by Sharon A. Shrock William C. CoscarelliCriterion-Referenced Test Development is designed specifically for training professionals who need to better understand how to develop criterion-referenced tests (CRTs). This important resource offers step-by-step guidance for how to make and defend Level 2 testing decisions, how to write test questions and performance scales that match jobs, and how to show that those certified as ?masters? are truly masters. A comprehensive guide to the development and use of CRTs, the book provides information about a variety of topics, including different methods of test interpretations, test construction, item formats, test scoring, reliability and validation methods, test administration, a score reporting, as well as the legal and liability issues surrounding testing. New revisions include: Illustrative real-world examples. Issues of test security. Advice on the use of test creation software. Expanded sections on performance testing. Single administration techniques for calculating reliability. Updated legal and compliance guidelines.Order the third edition of this classic and comprehensive reference guide to the theory and practice of organizational tests today.
A Critical Analysis of Basic Income Experiments for Researchers, Policymakers, and Citizens: The Devil's In The Caveats (Exploring the Basic Income Guarantee)
by Karl WiderquistAt least six different Universal Basic Income (UBI) experiments are underway or planned right now in the United States, Canada, the United Kingdom, Finland, and Kenya. Several more countries are considering conducting experiments. Yet, there seems to be more interest simply in having UBI experiments than in exactly what we want to learn from them. Although experiments can produce a lot of relevant data about UBI, they are crucially limited in their ability to enlighten our understanding of the big questions that bear on the discussion of whether to implement UBI as a national or regional policy. And, past experience shows that results of UBI experiments are particularly vulnerable misunderstanding, sensationalism, and spin. This book examines the difficulties of conducting a UBI experiment and reporting the results in ways that successfully improve public understanding of the probable effects of a national UBI. The book makes recommendations how researchers, reporters, citizens, and policymakers can avoid these problems and get the most out of UBI experiments.
Critical Analysis of Organizations: Theory, Practice, Revitalization
by Catherine Joan Casey`Catherine Casey has written an excellent book that provides a lucid and comprehensive critical analysis of organizations....[It] extends in reach and relevance beyond the specific field of organization studies and the sociology of organizations to encompass broader intellectual developments that have had a significant impact on contemporary sociology and cultural studies' - Barry Smart, Professor of Sociology, University of Portsmouth `I anticipate that it will prove to be an attractive book in organization studies, industrial sociology and general sociology. I am sure that this will be a book that will make a major impact' - Mike Reed, Professor of Organization Theory, Lancaster University In this comprehensive and scholarly book, the essential critical strands in organizational analysis are explained. It examines how central traditions have realigned in relation to the challenge of postmodernism and the new reflexive turn in organizational studies. Judicious, innovative and written with the needs of students in mind, this book offers a renewed and revitalized critical accent in organization studies - one that focuses on existing and emerging social tendencies, contestations and struggles. It will be essential reading for senior students of organization studies and sociology.
A Critical Analysis of the Contributions of Notable Black Economists (Interdisciplinary Research Series in Ethnic, Gender and Class Relations)
by Kojo A. QuarteyThis book introduces and critically analyzes the achievements of major black economists and their contributions to the realm of economic thought. The book begins with a brief overview of the contribution of Africans to philosophy and economic thought and goes on to discuss individuals who have made the most significant contributions to this field. There is particular reference to their background and influences including a critical analysis of individual thought. Kojo Quartey's book provides an essential supplement to any economic history text.
A Critical Appraisal of Germany's Thermal Retrofit Policy: Turning Down the Heat (Green Energy and Technology)
by Ray Galvin Minna Sunikka-BlankGermany is seen as a leader in thermal retrofit policy and practice, but how effective is its approach? A Critical Appraisal of Germany's Thermal Retrofit Policy examines this policy in context and assesses its effectiveness. It finds that technical constraints and the costs of retrofitting reduce the rate of progress, while planning underestimates the influence of user behavior in the form of rebound and prebound effects. A key finding is that savings can be maximized within a policy that understands the actual behavior and motivation of households, the area where most energy savings are already taking place. The book suggests a new policy paradigm that would encourage a better balance of partial and comprehensive retrofits, utilizing household behavior changes based on a better understanding of fuel saving motivation and fuel price elasticity. In this approach, the thermal building regulations would be made more flexible so that policymakers would: - Promote partial, transitional and cost-optimal retrofits, which are more certain to pay back through fuel savings if they are appropriate to building typology and homeowner budgets. - Promote comprehensive retrofits for reasons other than economic gain, focusing instead on the comfort and environmental benefits of energy-efficient homes. - Invest more heavily in educating households to heat economically, learning from the prebound effect so as to maximize the utility of the homes they currently occupy, and base payback time calculations on actual consumption. The results and findings of this book would be of interest to policymakers, researchers and graduate students alike.
A Critical Approach to Climate Change Adaptation: Discourses, Policies and Practices (Routledge Advances in Climate Change Research)
by Silja Klepp Libertad Chavez-RodriguezThis edited volume brings together critical research on climate change adaptation discourses, policies, and practices from a multi-disciplinary perspective. Drawing on examples from countries including Colombia, Mexico, Canada, Germany, Russia, Tanzania, Indonesia, and the Pacific Islands, the chapters describe how adaptation measures are interpreted, transformed, and implemented at grassroots level and how these measures are changing or interfering with power relations, legal pluralismm and local (ecological) knowledge. As a whole, the book challenges established perspectives of climate change adaptation by taking into account issues of cultural diversity, environmental justicem and human rights, as well as feminist or intersectional approaches. This innovative approach allows for analyses of the new configurations of knowledge and power that are evolving in the name of climate change adaptation. This volume will be of great interest to students and scholars of climate change, environmental law and policy, and environmental sociology, and to policymakers and practitioners working in the field of climate change adaptation.
A critical approach to the social acceptance of renewable energy infrastructures: Going beyond green growth and sustainability
by Susana Batel David RudolphThis book provides a critical approach to research on the social acceptance of renewable energy infrastructures and on energy transitions in general by questioning prevalent principles and proposing specific research pathways and lines of inquiry that look beyond depoliticised, business-as-usual discourses and research agendas on green growth and sustainability. It brings together authors from different socio-geographical and disciplinary backgrounds within the social sciences to reflect upon, discuss and advance what we propose to be five cornerstones of a critical approach: overcoming individualism and socio-cognitivism; repoliticisations – recognising and articulating power relations; for interdisciplinarity; interventions – praxis and political engagement with research; and overcoming localism and spatial determinism: As such, this book offers academics, students and practitioners alike a comprehensive perspective of what it means to be critical when inquiring into the social acceptance of renewable energy and associated infrastructures.
A Critical Bibliography of Adam Smith
by Hiroshi MizutaThis critical bibliography of Adam Smith takes as its starting point the Kress Library of Business and Economics’ 1939 catalogue of its Vanderblue Collection of Smithiana. Since the bicentenary of The Wealth of Nations in 1976, the rate of international publication markedly accelerated, significantly extending the scope of this bibliography beyond 1939. Its scope has been further enlarged via the inclusion of essays on the diffusion process while the inclusion of all works in the chronological main bibliography gives an overview of the scope of this process. The notes appended to the entries provide a running commentary to the gathering pace of publication and the entries are organised chronologically with systematic annotation throughout.
Critical Capacity Development
by Farhad Analoui Joseph Kwadwo DanquahThis book contributes to our understanding of a neglected and poorly-understood concept within the development field: 'capacity development' in the context of human and organisational sustainable development. Relating 'capacity development' to other perspectives in development thinking and practice and giving an account of the concept's genesis, the book introduces readers to recent empirical research initiatives that help to elucidate the concepts of capacity, capacity development, and capacity management. While capacity development initiatives and programmes have been used by most international and national agencies over the course of the last five decades, the term means different things to different people and especially to different major players in the international community. This weakens its effectiveness. This book therefore strives first of all to set ground rules that can be utilised by international aid providers such as UNDP, OECD, World Bank, and CIDA and practitioners alike.
Critical Chain
by Eliyahu M. GoldrattA business novel focusing on project management. The novel aims to provoke readers to examine and reassess their business practices and transform the thinking and actions of managers.
Critical Company Law
by Lorraine TalbotThe second edition of Critical Company Law provides a framework in which to understand how the company functions in society and a thorough grounding in modern legal doctrine. It shows how modern company law is shaped by a multi-layered history of politics, ideology, economics and power. Through the lens of political economic theory the book shows how the company becomes the mechanism through which the state makes political choices about distributing societies’ wealth and through which it responds to economic crises. The current law reflects an economy marked by a disjuncture between the low profits of the productive economy and the high profits of the finance economy. Critical Company Law examines areas of company law to show how they reflect a fragile economy inexorably drawn to social and economic inequality and short-termism. These include: • The Doctrine of Separate Corporate Personality • Groups of Companies and Tort Liabilities • Company Formation and the Constitution • Directors’ Duties and Authority • Corporate Capacity • Shares and Shareholders • Raising and Maintaining Capital • Minority Protection In this uniquely hybrid book the legal topics are treated with detail and clarity, providing an engaging introduction to the key topics required for a student of company law.
Critical Condition
by Donald L. Barlett James B. SteeleExposing the most controversial, little-known practices of America’s most flawed system, Time magazine’s Pulitzer Prize-winning investigative team pulls back the curtain on the health care industry to explain exactly how things grew so out of control. Dirty examination and operating rooms in doctor’s offices and hospitals . . . Health care executives pulling in millions in bonuses for denying treatment to the sick . . . More than 100 million people with inadequate or no medical coverage . . . This may sound like the predicament of a third-world nation, but this is America’s health care reality today. The U. S. spends more on health care than any other nation, yet our benefits are shrinking and life expectancy is shorter here than in countries that spend significantly less per capita. Meanwhile, HMOs, pharmaceutical companies, and hospital chains reap tremendous profits, while politicians—beholden to insurers and drug companies—enact legislation for the benefit of the few rather than the many, while the entire system is on the verge of collapse. In CRITICAL CONDITION, award-winning investigative journalists Donald L. Barlett and James B. Steele expose the horror of what health care in America has become. They profile patients and doctors trapped by the system and offer startling personal stories that illuminate what’s gone wrong. Doctors tell of being second-guessed and undermined by health care insurers; nurses recount chilling tales of hospital meltdowns; patients explain how they’ve been victimized by a system that is meant to care for them. Drug companies profit by selling pills in the same manner that Madison Avenue sells soap, while Wall Street rakes in billions by building up and then tearing down health care businesses. And politicians pass legislation perpetuating the injustices and out-right fraud the system encourages. By analyzing the industry and offering an insightful prescription for getting it back on the right track, CRITICAL CONDITION is an enormously compelling investigative work that addresses the concerns of every American.
Critical Connections: Promoting Economic Growth and Resilience in Europe and Central Asia (Europe and Central Asia Studies)
by David Michael GouldCritical Connections examines how trade, investment, migration, and other linkages among countries drive economic growth in the Europe and Central Asia region. The study breaks new ground by using a multidimensional approach that recognizes how each connectivity channel for growth is likely to be affected by the strength of other channels. This multidimensional view makes it easier to see that diversity in country connections and balance in all channels of connectivity are critical for achieving the greatest impact on growth. Europe and Central Asia provides a great laboratory for observing the role of multidimensional connectivity in action. The region’s 30 countries vary widely in the openness of their economies. Its collective experience shows how the various elements of cross-border connectivity work together to accelerate progrowth knowledge transfers, which in turn boost productivity through participation in today’s global value chains. A country’s economic partner might be just as important as the type of connection. Being well connected to highly connected countries can provide benefits beyond being well connected to comparatively isolated countries. Although greater connectivity can expose countries to external shocks, the report presents fact-based argument for policies that seek to build deeper and more diverse connections within the Europe and Central Asia region and globally. The message is timely. Europe’s once-confident march toward economic integration has slowed over the past decade, with voices in many countries questioning the wisdom of opening to the global economy. Critical Connections serves as a reminder to citizens and policy makers that greater regional and global connectivity has been a tremendous “convergence machine,†? raising living standards of lower-income countries toward those of wealthier middle- to high-income countries.
Critical Conversations For Dummies
by Christina Tangora SchlachterThe easy way to communicate best when it matters mostMost people are aware of the importance of handling critical conversations well. However, when it comes down to actually being in a difficult situation that calls for key communication skills, many do not know how to practically apply their own thoughts.Critical Conversations For Dummies is a step-by-step reference for the variety of crucial conversations life presents in the workforce. It's packed with strategies for preparing for high-stakes situations; being persuasive (not abrasive); knowing the value of assertive communication; resolving failed promises and missed deadlines; maintaining morale when firing staff; getting new employees off on the right foot; managing staff relations and strengthening team relationships; understanding audience needs and motivations to get positive results; altering confrontational language to cooperative language during difficult conversations; and building relationships in the face of conflict.Improve communication skills in crucial conversationsAvoid common pitfalls and emotional tendenciesDiscover the benefits of success in crucial conversations This book is especially relevant to the hundreds of thousands of leaders who are tasked with multiple duties, whether addressing complex problems from stakeholders or achieving exceptional results from staff.
Critical Debates in Tourism
by Tej Vir SinghIn this volume tourism experts collectively discuss and debate some intriguing questions that the tourism industry poses, such as the relevance of mass tourism, the dilemma of authenticity, whether small tourism is beautiful, whether volunteer tourism is benign, whether tourism contributes to climate change, as well as many others. The book brings together the expertise of 35 renowned international scholars of tourism to examine these perplexing issues. Multidisciplinary in its content, it touches upon anthropology, sociology, geography, climatology, biosciences, and planning and development aspects of tourism. The book provides a dialogue for an academic discussion which challenges research conservatism and stereotypes in tourism studies. It will encourage scholars to test the consistency of critical notions whose heuristic value is often taken for granted. The book will benefit graduates, research scholars and those involved in organizing the industry sustainably.
Critical Discourse Analysis of Chinese Advertisement: Case Studies of Household Appliance Advertisements from 1981 to 1996
by Chong WangThis book reflects the chronological changes in Chinese cultural values, social relations, economy and politics by critically analyzing the Chinese advertising discourse. The work is based on research into the ideological values portrayed in Chinese household appliance advertisements in the 1980s - 1990s. The analytical framework covers a variety of methods: critical discourse analysis, chronological analysis, visual and verbal analysis, and qualitative and quantitative analysis. The findings suggest that ideological values consciously or unconsciously manifested by the visual and verbal devices in the Chinese advertisements moved in a pattern from simplicity to diversity, from being politically-oriented to being economically and profit-oriented, from conservatism to globalization and westernization, in keeping with the progression of the Chinese economic reform. The findings further indicate that the ideological values in the Chinese household appliance advertisements are embedded in the advertising language and illustrations. Lastly, the work reveals the reality of Chinese politics, economy and society at a time when China experienced the growth of the market economy and evolution of Chinese mainstream ideologies, and demonstrates the impacts of these changes on the ideological meanings in advertisements. This book will help readers discover the more profound meanings behind the superficial content of Chinese advertisements.
Critical Economic Methodology: A Personal Odyssey
by Lawrence BolandLawrence Boland takes issue with both economic methodologists and practicing economists. He argues that there has been too much 'methodology for methodology's sake' and that mainstream economics might benefit by using methodology to take a critical look at economic theory.
Critical Encounters: Capitalism, Democracy, Ideas
by Wolfgang StreeckAn anthology of long-read book reviews by one of the European left&’s foremost political economistsFrom the acclaimed author of How Will Capitalism End? comes an omnibus of long-form critical essays engaging with leading economists and thinkers. Critical Encounters draws on Wolfgang Streeck&’s inimitable writing for the London Review of Books and New Left Review, among other publications. It opens with treatments of two contrasting historical eras—factory capitalism and financialization—and three of the world&’s major economies: the United States, France and Germany. A middle section surveys the hollowing out of Western democracies and reviews Yanis Varoufakis&’s &“strange but indispensable&” memoir of the eurozone crisis. Delving into the world of ideas, Streeck discusses the work of Quinn Slobodian, Mark Blyth, Jürgen Habermas and Perry Anderson. Finally, he zooms out to compare his home discipline of sociology to natural history, giving a remarkable and non-deterministic reading of Charles Darwin. In the preface, Streeck reflects on the art (or craft) of book reviewing and the continuing merits of the book form. Critical Encounters also includes a series of &“Letters from Europe,&” penned as the coronavirus descended upon the Continent.
Critical Essays in Sport Management: Exploring and Achieving a Paradigm Shift
by Andy Gillentine Robert Baker Jacquelyn CuneenThis collection of essays, written by a number of respected sport management scholars, addresses many of the challenges and issues facing today's sport management academic programs. It is intended to begin a professional and scholarly discussion to identify the best, or at least the most logical, paths to follow for sport management programs and the industry with which they are so closely aligned. Contributors, invited to participate based on their recognized areas of expertise, address specific topics using their own unique voices and writing styles. In the ebook version, essays link to video introductions by the authors and to online discussion forums where readers can respond to the issues presented in the essays. From the Preface: The field of sport management stands at an academic crossroads; the essays in this book address the following and other emerging questions: Should our successful field of study continue to model other disciplines and perpetuate their successes, as well as their shortcomings, or should we determine our own specific model for academic success? How are we doing in preparing future sport managers to perform in the industry and on the global stage? Where do we belong in the scheme of academe? The book's goal is to generate discussion among sport management professors, industry professionals who serve as adjunct faculty and participate on sport management program advisory boards, doctoral students who intend to teach in sport management programs, and others who explore and critique higher education in general.
Critical Event Studies: Approaches To Research (Routledge Advances in Event Research Series)
by Karl Spracklen Ian R. LamondWithin events management, events are commonly categorised within two axes, size and content. Along the size axis events range between the small scale and local, through major events, which garner greater media interest, to internationally significant hallmark and mega events such as the Edinburgh Festival and the Tour de France. Content is frequently divided into three forms – culture, sport or business. However, such frameworks overlook and depoliticise a significant variety of events, those more accurately construed as protest.This book brings together new research and theories from around the world and across sociology, leisure studies, politics and cultural studies to develop a new critical pedagogy and critical theory of events. It is the first research monograph that deals explicitly with the concept of critical event studies (CES), the idea that it is impossible to explore and understand events without understanding the wider social, cultural and political contexts. It addresses questions such as can the occupation and reclamation of specific spaces by activists be understood as events within its framework? And is the activity of activists in these spaces a leisure activity? If those, and other similar activities, can be read as events and leisure, what does admitting them into the scope of events management and leisure studies mean for our understanding of them and how the study of events management is to be conceptualised? This title will be of interest to undergraduate and postgraduate students on events management and related courses and scholars interested in understanding the ways in which events are constructed by the social, the cultural and the political.
Critical Factors for Adoption of Customer Relationship Management: A Study of Palestine SMEs (SpringerBriefs in Business)
by Omar Hasan Salah Zawiyah Mohammad Yusof Hazura Mohamed Nur Fazidah EliasThis book explores the challenges in adopting customer relationship management (CRM) models in developing countries, with a focus on Palestine. Examining the cultural, organizational, and technological contexts, it reveals how these factors create adoption gaps, impacting customer pressure, employee engagement, and security. The narrative, enriched by real-world examples from Palestine, underscores the unique hurdles faced by firms in such environments. Emphasizing the central role of customers in business, the book delves into the initiatives many firms take to enhance customer services, target profitable segments, and improve acquisition and retention. However, in developing nations, these efforts encounter distinctive challenges. The book offers a practical CRM model tailored to the specific needs of small and medium-sized enterprises (SMEs), illustrating how technology can elevate competitiveness. With a strategic perspective, it positions CRM as a catalyst for SMEs to navigate the complexities of the dynamic economy, providing actionable insights for professionals, scholars, and business management students. This comprehensive guide encapsulates the nuances of CRM adoption, making it an invaluable resource for those seeking sustainable growth in developing country contexts.
Critical Factors for Berth Productivity in Container Terminal
by Shouyang Wang Bo LuThis book is a comparative study of the critical factors in berth productivity in Chinese and South Korean container terminals. It first defines the concept of berth productivity, and then establishes a regression model to evaluate the productivity factor. With the results obtained for the leading Asian container terminals it identifies the relationship between critical factors for berth productivity and their order of importance. The findings provide guidelines for terminal operators to improve berth productivity.
The Critical Few: Energize Your Company’s Culture by Choosing What Really Matters
by Jon Katzenbach James Thomas Gretchen AndersonIn a global survey by the Katzenbach Center, 80 percent of respondents believed that their organization must evolve to succeed. But a full quarter of them reported that a change effort at their organization had resulted in no visible results. Why? The fate of any change effort depends on whether and how leaders engage their culture: the self-sustaining patterns of behaving, feeling, thinking, and believing that determine how things are done in an organization. Culture is implicit rather than explicit, emotional rather than rational—that's what makes it so hard to work with, but that's also what makes it so powerful. For the first time, this book lays out the Katzenbach Center's proven methodology for identifying your culture's three most critical elements: traits, characteristics that are at the heart of people's emotional connection to what they do; keystone behaviors, actions that would lead your company to succeed if they were replicated at a greater scale; and authentic informal leaders, people who have a high degree of “emotional intuition” or social connectedness.By leveraging these critical few elements, you can tap into a source of catalytic change within your organization. People will make an emotional, not just a rational, commitment to new initiatives. You will elicit enthusiasm and creativity and build the kind of powerful company that people recognize for its innate value and effectiveness.
The Critical First Years of Your Professional Life
by Robert L. Dilenschneider Mary Jane GenovaFaced with an unstable economy, recent college grads need more expert guidance than ever to land that dream job and make it rewarding and meaningful. This invaluable guide--revised to meet the specific challenges of today's fast-evolving job market--shows how you can use your talent, originality, and initiative to sharpen your competitive edge. The first years of your professional life are critical to long-term success in any field. The skills you acquire, the contacts you make, and the lessons you learn will help you remain involved, adaptable, and always ahead of the curve. Now a seasoned veteran of the workplace shares his insights, tips, and experiences in a thoroughly updated edition of a career-planning classic.