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Genetic Programming for Production Scheduling: An Evolutionary Learning Approach (Machine Learning: Foundations, Methodologies, and Applications)

by Fangfang Zhang Su Nguyen Yi Mei Mengjie Zhang

This book introduces readers to an evolutionary learning approach, specifically genetic programming (GP), for production scheduling. The book is divided into six parts. In Part I, it provides an introduction to production scheduling, existing solution methods, and the GP approach to production scheduling. Characteristics of production environments, problem formulations, an abstract GP framework for production scheduling, and evaluation criteria are also presented. Part II shows various ways that GP can be employed to solve static production scheduling problems and their connections with conventional operation research methods. In turn, Part III shows how to design GP algorithms for dynamic production scheduling problems and describes advanced techniques for enhancing GP’s performance, including feature selection, surrogate modeling, and specialized genetic operators. In Part IV, the book addresses how to use heuristics to deal with multiple, potentially conflicting objectives in production scheduling problems, and presents an advanced multi-objective approach with cooperative coevolution techniques or multi-tree representations. Part V demonstrates how to use multitask learning techniques in the hyper-heuristics space for production scheduling. It also shows how surrogate techniques and assisted task selection strategies can benefit multitask learning with GP for learning heuristics in the context of production scheduling. Part VI rounds out the text with an outlook on the future.Given its scope, the book benefits scientists, engineers, researchers, practitioners, postgraduates, and undergraduates in the areas of machine learning, artificial intelligence, evolutionary computation, operations research, and industrial engineering.

Genetic Testing and the Governance of Risk in the Contemporary Economy: Comparative Reflections in the Insurance and Employment Law Contexts (Ius Comparatum - Global Studies in Comparative Law #34)

by Lara Khoury Adelle Blackett Lukas Vanhonnaeker

This book addresses emerging questions concerning who should bear responsibility for shouldering risk, as well as the viability of existing and experimental governance mechanisms in connection with new technologies. Scholars from 14 jurisdictions unite their efforts in this edited collection to provide a comparative analysis of how various legal systems are tackling the challenges produced by the legal aspects of genetic testing in insurance and employment. They cover the diverse set of norms that surround this issue, and share insights into relevant international, regional and national incursions into the field. By doing so, the authors offer a basis for comparative reflection, including on whether transnational standard setting might be useful or necessary for the legal aspects of genetic testing as they relate to the insurance and employment contexts. The respective texts cover a broad range of topics, including the prevalence of genetic testing in the contexts of insurance and employment, and policy factors that might affect this prevalence, such as the design of national health or social insurance systems, of private insurance schemes or the availability of low-cost direct-to-consumer genetic testing. Further, the field of genetics is gaining in importance at the international and regional levels. Relevant concepts – mainly genetic tests and genetic data/information – have been internationally defined, and these definitions have influenced definitions adopted nationally. International law also recognizes a “special status” for human genetic data. The authors therefore also consider these definitions and the recognition of the special status of human genetic data within regional and national legal orders. They investigate the range of norms that specifically address the use of genetic testing in employment and insurance, encompassing international sources – including human rights norms – that may be binding or non-binding, as well national statutory, regulatory and soft-law mechanisms. Accordingly, some of the texts examine general frameworks relevant to genetic testing in each country, including those that stem from general anti-discrimination rules and norms protecting rights to autonomy, self-determination, confidentiality and privacy. In closing, the authors provide an overview of the efficiency of their respective legal regimes’ approaches – specific and generalist – to genetic testing or disclosure of genetic information in the employment or insurance contexts, including the effect of lack of legal guidance. In this regard, some of the authors highlight the need for transnational action in the field and make recommendation for future legal developments.

Genetically Modified Democracy: Transgenic Crops in Contemporary India (Yale Agrarian Studies Series)

by Aniket Aga

How the debate over genetically modified crops in India is transforming science and politics Genetically modified or transgenic crops are controversial across the world. Advocates see such crops as crucial to feeding the world&’s growing population; critics oppose them for pushing farmers deeper into ecological and economic distress, and for shoring up the power of agribusinesses. India leads the world in terms of the intensity of democratic engagement with transgenic crops. Anthropologist Aniket Aga excavates the genealogy of conflicts of interest and disputes over truth that animate the ongoing debate in India around the commercial release of transgenic food crops. The debate may well transform agriculture and food irreversibly in a country already witness to widespread agrarian distress, and over 300,000 suicides by farmers in the last two decades. Aga illustrates how state, science, and agrarian capitalism interact in novel ways to transform how democracy is lived and understood, and sheds light on the dynamics of technological change in populous, unequal polities.

Genetics: The Science of Life (Genetics Ser.)

by Susan Schafer

The field of genetics is constantly in the news, and it is a major part of national and state standards for science education - both for learning the scientific concepts and principles themselves, and for enhancing critical thinking and providing students with a bigger picture of how science and scientific inquiry change the world.Written by a widely-respected author and teacher, "Genetics: The Science of Life" is designed to supplement the information provided in science textbooks and provide a platform for student discussions and debate on the latest developments in this fast-growing field. Each highly illustrated book focuses on a particular aspect of genetics in language that will appeal to readers ages 12 and up. Full-color line-art illustrates complex scientific concepts, and a variety of thematic sidebars highlight particular elements of genetics studies with engaging, real-life examples.

Genetics and Insurance

by T. McGleenan U. Wiesing F. Ewald

Compiled by a well known and respected team of editors and contributors from interdisciplinary backgrounds, this book has its origins in the Euroscreen project, a research project funded by the European Commission to examine the legal and ethical issues arising from the use of genetic testing and screening since 1990. Contributors from members of a sub-group look at the likely impact of genetic testing on insurance.It will be published at a point when the significant controversy surrounding this issue will have intensified throughout the European Union. Although taking a European perspective, it addresses US issues where there is a strong interest in comparative legislative strategies, taking a themed approach, this book looks comprehensively at the basis issues with an analytical rather than a descriptive approach.

The Geneva Papers: 40 Years At The Cutting Edge Of Research In Insurance Economics

by Christophe Courbage

In January 1976, Raymond Barre, the first President of The Geneva Association, and Orio Giarini, its first Secretary General, founded The Geneva Papers on Risk and Insurance with the main goal of supporting and encouraging research in the economics of risk and insurance. At that time, research in the field of insurance was still embryonic and insurance was regarded as peripheral social activity. When sustained economic growth gained traction, the function of insurance gradually emerged as a key contributor to economic development. By integrating uncertainty into economic theory and benefiting from the progress of both financial economics and decision theory, research developed further in the field of insurance economics and risk management, and is now prolific. The Geneva Papers on Risk and Insurance undeniably contributed to this evolution and its impact on research in insurance has largely exceeded what its two founding members could have expected. This volume is a special collection of papers celebrating 40 Years of The Geneva Papers on Risk and Insurance. The collection looks back at the storied history of The Geneva Papers on Risk and Insurance and features papers from some of the esteemed authors who have contributed to the journal in its lifetime. This collection of papers highlights just a few of the many themes addressed in the papers published by the journal since it was created. Nevertheless, the selection exemplifies the richness and variety of topics the field of insurance covers.

Genial erfolgreich: Wie du mit der richtigen Einstellung im Leben gewinnen kannst

by Marcus Kutrzeba

Wieso schaffen nur 10% der gegründeten Unternehmen weltweit das wirtschaftliche Überleben? Weshalb fühlen sich immer mehr Unter-Dreißigjährige schon ausgelaugt? Warum liegt die Scheidungsrate international bei knapp 50%? Die Antworten darauf liefert dieses Buch, das den gedanklichen Befreiungsschlag unternimmt, der viele Probleme lösen kann in Beziehungen, Firmen und Organisationen jeglicher Art. Der Weg führt über die innere Einstellung. Lebensglück und Erfolg sind damit untrennbar verbunden. Ergänzt und untermauert wird der Mindset-Ansatz des Autors durch praktische, unterhaltsame und alarmierende Anekdoten aus seiner langjährigen Seminar- und Unterrichtspraxis in Firmen und Hochschulen - dort, wo die Menschen stark fremdbestimmt und ihr Denken sowie ihre Haltung entsprechend beeinflusst sind.

El genio que llevamos dentro: Innovación como nadie te enseñó

by Federico Fros Campelo

¿Qué es innovar? ¿Hace falta creatividad, ambición, conocimientos, improvisación? ¿Cuánto de la circuitería cerebral se pone en marcha en la innovación? ¿Es crear algo que no existe o mejorar lo que ya está? ¿Cómo juegan las necesidades de los clientes en la innovación? En este libro, el autor explora el concepto desde perspectivas distintas. La velocidad a la que están sucediendo los cambios en el mundo es de vértigo. Entonces, ¿cómo ingeniártelas para que tu proyecto funcione? ¿Cómo lograr que se te ocurran ideas que sirvan en serio? La innovación se está difundiendo por todos lados. Ves un video en YouTube y te habla del asunto, vas a un evento y aparecen charlas sobre el tema. Buenísimo para entretenerte, pero... ¿cómo innovás en lo tuyo? Por más nube de hashtags disruptivos que te tiren encima, nadie nunca te enseñó realmente a innovar. Hasta ahora. Más irreverente y frontal que antes, Federico Fros Campelo llega con su sexto libro. Acá no vas a encontrar cantinelas descriptivas ni tsunamis de teoría. En este libro te cuenta de manera práctica cómo se puede innovar de verdad. Al combinar el funcionamiento de tu cabeza con los de las organizaciones y el mercado, su método de Innovación Cognitiva © te ofrece cinco pasos que van a cambiar radicalmente tu manera de pensar y de ver el mundo. Cinco pasos que te llevarán a producir ideas imprescindibles para los que compren tu trabajo, consuman tus servicios y productos. O te reinventás o te comen los leones. Aquí, tu guía de supervivencia.

The Genius Habit: How One Habit Can Radically Change Your Work and Your Life

by Laura Garnett

Are you tired of feeling burnt out and anxious in your career? Do you dream of reaching new heights of productivity and success?In this empowering guide, performance strategist Laura Garnett reveals the powerful secret to breaking free from burnout and achieving unparalleled productivity. It all lies in embracing the unique genius within you!By leveraging the full potential of your authentic self, you'll discover a wellspring of untapped abilities that will revolutionize your career and life.Discover Your Genius: Through insightful self-assessments and eye-opening exercises, uncover your hidden talents and passions to recognize and embrace what makes you truly exceptional.Banish Burnout: Say goodbye to the overwhelming stress and fatigue that have been holding you back with effective strategies to combat burnout, maintain work-life balance, and rekindle your passion for your career.Double Your Productivity: Unleash the full force of your genius to achieve exceptional levels of productivity by aligning your work with your natural strengths, making every task a rewarding and fulfilling experience.Career Clarity: Gain crystal-clear clarity on your professional path and develop a clear roadmap for success.Overcome Career Anxiety: Tackle the nagging doubts and fears that have been holding you back, and learn to trust in your unique abilities and make confident decisions for your career growth.Work Smart, Not Hard: Say goodbye to ineffective strategies and endless hustle. The Genius Habit empowers you to work smarter by leveraging your innate talents, saving time, and achieving remarkable results.Authentic Leadership: Embrace your authentic self to become an inspiring and impactful leader who leads with confidence, compassion, and purpose, leaving a lasting impression on those around you.Don't settle for mediocrity in your career. Embrace The Genius Habit and set yourself on a path of fulfillment, success, and boundless productivity.

Genius Makers: The Mavericks Who Brought AI to Google, Facebook, and the World

by Cade Metz

<P><P>THE UNTOLD TECH STORY OF OUR TIME <P><P> What does it mean to be smart? To be human? What do we really want from life and the intelligence we have, or might create? With deep and exclusive reporting, across hundreds of interviews, New York Times Silicon Valley journalist Cade Metz brings you into the rooms where these questions are being answered. Where an extraordinarily powerful new artificial intelligence has been built into our biggest companies, our social discourse, and our daily lives, with few of us even noticing. Long dismissed as a technology of the distant future, artificial intelligence was a project consigned to the fringes of the scientific community. <P><P> Then two researchers changed everything. One was a sixty-four-year-old computer science professor who didn’t drive and didn’t fly because he could no longer sit down—but still made his way across North America for the moment that would define a new age of technology. The other was a thirty-six-year-old neuroscientist and chess prodigy who laid claim to being the greatest game player of all time before vowing to build a machine that could do anything the human brain could do. They took two very different paths to that lofty goal, and they disagreed on how quickly it would arrive. But both were soon drawn into the heart of the tech industry. Their ideas drove a new kind of arms race, spanning Google, Microsoft, Facebook, and OpenAI, a new lab founded by Silicon Valley kingpin Elon Musk. But some believed that China would beat them all to the finish line. <P><P> Genius Makers dramatically presents the fierce conflict between national interests, shareholder value, the pursuit of scientific knowledge, and the very human concerns about privacy, security, bias, and prejudice. Like a great Victorian novel, this world of eccentric, brilliant, often unimaginably yet suddenly wealthy characters draws you into the most profound moral questions we can ask. And like a great mystery, it presents the story and facts that lead to a core, vital question: How far will we let it go?

The Genius of Israel: The Surprising Resilience of a Divided Nation in a Turbulent World

by Dan Senor Saul Singer

How has a small nation of 9 million people, forced to fight for its existence and security since its founding and riven by ethnic, religious, and economic divides, proven resistant to so many of the societal ills plaguing other wealthy democracies?Why do Israelis have among the world&’s highest life expectancies and lowest rates of &“deaths of despair&” from suicide and substance abuse? Why is Israel&’s population young and growing while all other wealthy democracies are aging and shrinking? How can it be that Israel, according to a United Nations ranking, is the fourth happiest nation in the world? Why do Israelis tend to look to the future with hope, optimism, and purpose while the rest of the West struggles with an epidemic of loneliness, teen depression, and social decline? Dan Senor and Saul Singer, the writers behind the international bestseller Start-Up Nation, have long been students of the global innovation race. But as they spent time with Israel&’s entrepreneurs and political leaders, soldiers and students, scientists and activists, ultra-Orthodox Jews, Tel Aviv techies, and Israeli Arabs, they realized that they had missed what really sets Israel apart. Moving from military commanders integrating at-risk youth and people who are neurodiverse into national service, to high performing companies making space for working parents, from dreamers and innovators launching a duct-taped spacecraft to the moon, to bringing better health solutions to people around the world, The Genius of Israel tells the story of a diverse people and society built around the values of service, solidarity, and belonging. Widely admired for having the world&’s highest density of high-tech start-ups, Israel&’s greatest innovation may not be a technology at all, but Israeli society itself. Understanding how a country facing so many challenges can be among the happiest provides surprising insights into how we can confront the crisis of community, human connectedness, and purpose in modern life. Bold, timely, and insightful, Senor and Singer&’s latest work shines an important light on the impressive innovative distinctions of Israeli society—and what other communities and countries can learn.

The Genius of Opposites: How Introverts and Extroverts Achieve Extraordinary Results Together

by Jennifer B. Kahnweiler

Better TogetherFDR and Eleanor. Mick and Keith. Jobs and Woz. There are countless examples of introvert-extrovert partnerships who make brilliant products, create great works of art, and even change history together. But these partnerships don't just happen. They demand wise nurturing. The key, says bestselling author Jennifer Kahnweiler, is for opposites to stop emphasizing their differences and use approaches that focus them both on moving toward results. Kahnweiler's first-of-its-kind practical five-step process helps introverts and extroverts understand and appreciate each other's wiring, use conflicts to spur creativity, enrich their own skills by learning from the other, and see and act on things neither would have separately. Kahnweiler shows how to perform the delicate balancing act required to create a whole that is exponentially greater than the sum of its parts.

The Genius of the Beast: A Radical Re-vision of Capitalism

by Howard Bloom

Is global capitalism on its last legs? Is the era of American leadership over? Has the West begun a decline into a new Dark Age? Does American civilization deserve to survive? These are the unnerving questions raised by the Great Crash of 2009. This book resents a radically new answer, insisting that global society has only begun to realize its full potential. Bloom argues that there's a hidden mandate beneath the surface of capitalism: "It's struggling to whisper and rumble its message to you and me. That hidden imperative can lift us from economic crisis, can make us a leader in the next-generation economy, and can dramatically upgrade our ability to empower our fellow human beings." Bloom sees crisis as opportunity, opportunity for the whole human race. In more than eighty short, fast chapters, insights appear suddenly, like the quick bursts of flashbulbs, taking the reader on a sweeping tour of human history, from the Stone Age to the present. Every chapter conveys a radically new way to see the astonishing mechanism we call "Western Civilization." Author Howard Bloom marvels at how humans have turned toxic waste into food and fuel, trash into treasure, and garbage into gold. He shows how we've produced material miracles based on immaterial things--passion, persistence, and fantasy. He shows that what many regard as the end is just the beginning. The beginning of something you've never before imagined. The author explains why the secret to capitalism's next great leap does not lie in new financial tricks, but in tapping things right under our noses in radically new ways--that is, tapping our imagination, our desire to feel useful, our desire to help others, and our desire to be recognized for contributing to the welfare of humanity. The key to next-generation capitalism lies in a big-picture view that's utterly unlike anything you've previously perceived. A big-picture view that will startle you. A big-picture view with which you can ignite the world, get a new handle on your life, and help transform society. This brilliant, inspirational work of daring ideas and breath-taking research offers more than hope. It offers unseen levels of understanding. Understanding that can literally redefine what it means to be a human being.

The Genius Zone: The Breakthrough Process to End Negative Thinking and Live in True Creativity

by Gay Hendricks

Too often we live lives that we find unfulfilling, fail to reach our own potential, and neglect to practice creativity in our daily routines. Gay Hendricks's The Genius Zone offers a way to change that by tapping into your own innate creativity.Dr. Gay Hendricks broke new ground with his bestselling classic, The Big Leap, which has become an essential resource for coaches, entrepreneurs, executives, and health practitioners around the world. Originally published as The Joy of Genius, The Genius Zone has been updated and expanded throughout, making it the essential next step beyond The Big Leap.In The Genius Zone, Hendricks introduces his brilliant exercise, the Genius Move, a simple, life-altering practice that allows readers to end negative thinking and thrive authentically. By using the Genius Move, readers will learn to spend more of their lives in their zone of genius—where creativity flows freely and they are actively pursuing the things that offer them fulfillment and satisfaction. Filled with hands-on exercises and personal stories from the author, The Genius Zone is an essential guide to creative fulfillment. If you are committed to bringing forth your innate genius and making your largest possible creative contribution, The Genius Zone will become a trusted companion for the journey.

Genoa and the Sea: Policy and Power in an Early Modern Maritime Republic, 1559–1684 (The Johns Hopkins University Studies in Historical and Political Science #123)

by Thomas Allison Kirk

Genoa enjoyed an important and ever-changing role in the early modern Mediterranean world. In medieval times, the city transformed itself from a tumultuous maritime republic into a stable and prosperous one, making it one of the most important financial centers in Europe. When Spanish influence in the Mediterranean world began to decline, Genoa, its prosperity closely linked with Spain's, again had to reinvent itself and its economic stature. In Genoa and the Sea, historian Thomas Allison Kirk reconstructs the early modern Mediterranean world and closely studies Genoa's attempt to evolve in the ever-changing political and economic landscape. He focuses on efforts in the sixteenth and seventeenth centuries to revive shipbuilding and maritime commerce as a counterbalance to the city's volatile financial sector. A key component to the plan was a free port policy that attracted merchants and stimulated trade.Through extensive research and close reading of primary documents, Kirk discusses the underpinnings of this complex early modern republic. Genoa's transformations offer insight into the significant and sweeping changes that were taking place all over Europe.

Genocide, State Crime and the Law: In the Name of the State

by Jennifer Balint

Genocide, State Crime and the Law critically explores the use and role of law in the perpetration, redress and prevention of mass harm by the state. In this broad ranging book, Jennifer Balint charts the place of law in the perpetration of genocide and other crimes of the state together with its role in redress and in the process of reconstruction and reconciliation, considering law in its social and political context. The book argues for a new approach to these crimes perpetrated 'in the name of the state' - that we understand them as crimes against humanity with particular institutional dimensions that law must address to be effective in accountability and as a basis for restoration. Focusing on seven instances of state crime - the genocide of the Armenians by the Ottoman state, the Holocaust and Nazi Germany, Cambodia under the Khmer Rouge, apartheid South Africa, Ethiopia under Mengistu and the Dergue, the genocide in Rwanda, and the conflict in the former Yugoslavia - and drawing on others, the book shows how law is companion and collaborator in these acts of nation-building by the state, and the limits and potentials of law's constitutive role in post-conflict reconstruction. It considers how law can be a partner in destruction yet also provide a space for justice. An important, and indeed vital, contribution to the growing interest and literature in the area of genocide and post-conflict studies, Genocide, State Crime and the Law will be of considerable value to those concerned with law's ability to be a force for good in the wake of harm and atrocity.

Genoese Trade and Migration in the Spanish Atlantic, 1700–1830

by Catia Brilli

The Republic of Genoa was once a major commercial power. Following the Republic's decline in the seventeenth century, Genoese merchants adapted and thrived in the changing Atlantic market. Scholars have examined how other foreign merchant groups operated within the Spanish empire, but until now no one has examined how the Genoese adapted to the challenges of increasing competition in Atlantic trade. Here, Catia Brilli explores how Genoese intermediaries maintained a strong presence in Spanish colonial trade by establishing themselves at the port of Cadiz with its monopoly over American trade, and through gradually consolidating strong commercial ties with the R#65533;o de la Plata. Situated at the intersection of European, Atlantic, and Latin American history and making extensive use of Spanish, Italian, and Argentinian sources, Genoese Trade and Migration in the Spanish Atlantic, 1700–1830 provides a unique perspective on eighteenth- and early nineteenth-century transatlantic trade.

Genome Editing and Global Food Security: Molecular Engineering Technologies for Sustainable Agriculture (Earthscan Food and Agriculture)

by Zeba Khan Durre Shahwar Yasmin Heikal

With the rapid increase in the global population and changing climatic impacts on agriculture, this book demonstrates how genome editing will be an indispensable technique to overcome ongoing and prospective agricultural challenges. This book examines the role of genome editing in improving crop yields and contributing to global food security. It summarizes a range of genome editing techniques and discusses the roles they can play in producing a new generation of high-yielding, climate-ready crops. This includes site-specific nucleases, precision genome engineering, clustered regularly interspaced short palindromic repeats, and bioinformatics. It showcases how these gene editing techniques can tailor plants to not only increase yield-related traits but to also make them better suited to their environment and to be resistant to pests and extreme climatic events, such as droughts. The book also examines genome editing regulations and policies, the commercialization of genome-edited crops, and biosafety and biosecurity concerns. Overall, this book reveals and showcases how genome editing can improve crop resilience and production to address current and future agricultural challenges and alleviation of global food security concerns. This book will be of great interest to students and scholars of agricultural science, crop and plant science, genome editing, sustainable agriculture, biotechnology, and food security.

The Genome Odyssey: Medical Mysteries and the Incredible Quest to Solve Them

by Dr. Euan Angus Ashley

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human.In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome.These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.

Genomics and Society: "Legal, Ethical and Social Dimensions" (The\earthscan Science In Society Ser.)

by George Gaskell Martin W Bauer

The impact of genomics on society has been the focus of debate and conflict across the world. Contrasting views of risks and benefits, trust in science and regulation, the understanding of science, media coverage and mobilization of the public by civil society groups all have been cited as drivers of public opinion. The long running controversy is a signal that the public's view cannot be ignored in the development and implementation of new technologies arising out of genomics such as agricultural biotechnologies, genetic testing and the uses of genetic information, the cloning of human cells and tissues and transgenic animals. Written by a progressive international group of social scientists from Europe, North America and Japan, this volume presents a series of comparative perspectives on the social, ethical and legal implications of genomics. The result is a book which encapsulates the lessons to be learned from the controversies of the 1990s and raises the level of debate on the societal implications of new developments in genomics.

Genomics and the Reimagining of Personalized Medicine

by Richard Tutton

Drawing on insights from work in medical history and sociology, this book analyzes changing meanings of personalized medicine over time, from the rise of biomedicine in the twentieth century, to the emergence of pharmacogenomics and personal genomics in the 1990s and 2000s. In the past when doctors championed personalization they did so to emphasize that patients had unique biographies and social experiences in the name of caring for their patients as individuals. However, since the middle of the twentieth century, geneticists have successfully promoted the belief that genes are implicated in why some people develop diseases and why some have adverse reactions to drugs when others do not. In doing so, they claim to offer a new way of personalizing the prediction, prevention and treatment of disease. As this book shows, the genomic reimagining of personalized medicine centres on new forms of capitalization and consumption of genetic information. While genomics promises the ultimate individualization of medicine, the author argues that personalized medicine exists in the imaginative gap between the problems and limits of current scientific practices and future prospects to individualize medical interventions. A rigorous, critical examination of the promises of genomics to transform the economics and delivery of medicine, Genomics and the Reimagining of Personalized Medicine examines the consequences of the shift towards personalization for the way we think about and act on health and disease in society. As such, it will be of interest to scholars and students of the sociology of medicine and health, science and technology studies, and health policy.

Genomics in the Family Office

by Lauren H. Cohen Ronnie Stangler Spencer C. N. Hagist

Case

Genre Studies in Mass Media: A Handbook

by Art Silverblatt

The study of various types of programming is essential for critical analysis of the media and also offers revealing perspectives on society's cultural values, preoccupations, behavior, and myths. This handbook provides a systematic, in-depth approach to the study of media genres - including reality programs, game shows, situation comedies, soap operas, film noir, news programs, and more. The author addresses such questions as: Have there been shifts in the formula of particular genres over time? What do these shifts reveal about changes in culture? How and why do new genres - such as reality TV shows - appear? Are there differences in genres from one country to another? Combining theoretical approaches with concrete examples, the book reinforces one's understanding of the importance of genre to the creation, evolution, and consumption of media content. Each chapter in this reader-friendly book contains a detailed discussion of one of the theoretical approaches to genre studies, followed by Lines of Inquiry, which summarizes the major points of the discussion and suggests directions for analysis and further study. Each chapter also includes an example that illustrates how the particular theoretical approach can be applied in the analysis of genre. The author's careful linkage of different genres to the real world makes the book widely useful for those interested in genre study as well as media and culture, television studies, film studies, and media literacy.

"GEnron?" Markopolos versus General Electric (A)

by David Lane Jonas Heese

In August 2019, Harry Markopolos-the forensic accountant known for uncovering Bernie Madoff's Ponzi scheme-alleged that General Electric had committed accounting fraud totaling $38 billion, coining the term "GEnron" for perceived similarities with the 2001 accounting fraud at Enron that brought down that company and its auditor. Specifically, Markopolos claimed, GE would need to generate $29 billion in reserves against its insurance obligations, and restate its financials to recognize $9 billion in unreported losses on an oil subsidiary. Though GE management rejected these assertions, repeated writedowns and restatements of GE's performance since 2017 had made investors wary. They now scrambled to assess the merits of Markopolos's claims.

"GEnron"? Markopolos versus General Electric (B)

by David Lane Jonas Heese

Supplement to the (A) case that offers an assessment of the August 2019 Markopolos report on General Electric.

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