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Textbook of Clinical Trials in Oncology: A Statistical Perspective
by Susan Halabi and Stefan MichielsThere is an increasing need for educational resources for statisticians and investigators. Reflecting this, the goal of this book is to provide readers with a sound foundation in the statistical design, conduct, and analysis of clinical trials. Furthermore, it is intended as a guide for statisticians and investigators with minimal clinical trial experience who are interested in pursuing a career in this area. The advancement in genetic and molecular technologies have revolutionized drug development. In recent years, clinical trials have become increasingly sophisticated as they incorporate genomic studies, and efficient designs (such as basket and umbrella trials) have permeated the field. This book offers the requisite background and expert guidance for the innovative statistical design and analysis of clinical trials in oncology. Key Features: Cutting-edge topics with appropriate technical background Built around case studies which give the work a "hands-on" approach Real examples of flaws in previously reported clinical trials and how to avoid them Access to statistical code on the book’s website Chapters written by internationally recognized statisticians from academia and pharmaceutical companies Carefully edited to ensure consistency in style, level, and approach Topics covered include innovating phase I and II designs, trials in immune-oncology and rare diseases, among many others
A TextBook of Cost and Management Accounting 10 Edition - PART-I
by M. N. AroraThis book provides the students with thorough grounding in cost concepts, cost behaviour and methods, and techniques of cost and management accounting with an understanding of the uses and limitations of cost and financial data for managerial operations. The text of the subject matter has been presented in a student-friendly, simple and intelligible manner. Every discussion involving conceptual complexity is immediately illustrated by a numerical example. In addition, the book contains a liberal sprinkling of charts and diagrams so as to make the subject easily understandable and highlight its finer points. The subject matter has been organized on â first things firstâ basis for its logical presentation that sustains interest. The approach of the book is examination oriented. Thus, a good number of problems and solutions have been included in its chapters. Theoretical and numerical questions have been mostly selected from various examinations. Objective type questions have been given to serve as self test by students. This is an ideal book for self study.
Textbook of Epidemiology
by Lex Bouter Maurice Zeegers Tianjing LiTEXTBOOK OF EPIDEMIOLOGY The gold standard in epidemiological texts In the second edition of Textbook of Epidemiology, a distinguished team of researchers deliver an extensively updated and comprehensive exploration of epidemiological methods, illuminating the tools for studying the distribution and risk factors of health states and events in populations. An introduction to epidemiological methods with recent and broadly applicable examples End-of-chapter self-assessment questions for readers to check their understanding of key concepts, with answer keys and further enrichment materials available on a companion website A brand-new chapter covering methods for systematic reviews and meta-analysis Accessible material appropriate for clinical practitioners and researchers from around the world Perfect for professionals working in clinical medicine and public health, Textbook of Epidemiology will also earn a place in the libraries of allied health professionals seeking a one-stop resource or to re-immerse themselves in specific methodological topics and practices.
A Textbook of Graph Theory (Universitext)
by K. Ranganathan R. BalakrishnanGraph theory experienced a tremendous growth in the 20th century. One of the main reasons for this phenomenon is the applicability of graph theory in other disciplines such as physics, chemistry, psychology, sociology, and theoretical computer science. This textbook provides a solid background in the basic topics of graph theory, and is intended for an advanced undergraduate or beginning graduate course in graph theory. This second edition includes two new chapters: one on domination in graphs and the other on the spectral properties of graphs, the latter including a discussion on graph energy. The chapter on graph colorings has been enlarged, covering additional topics such as homomorphisms and colorings and the uniqueness of the Mycielskian up to isomorphism. This book also introduces several interesting topics such as Dirac's theorem on k-connected graphs, Harary-Nashwilliam's theorem on the hamiltonicity of line graphs, Toida-McKee's characterization of Eulerian graphs, the Tutte matrix of a graph, Fournier's proof of Kuratowski's theorem on planar graphs, the proof of the nonhamiltonicity of the Tutte graph on 46 vertices, and a concrete application of triangulated graphs.
Textbook of Medical Statistics: For Medical Students
by Xiuhua Guo Fuzhong XueThis book introduces basic concepts, principle, and methods of medical statistics systematically and practically, especially in the statistical design of the experiment in terms of the specific problems, adequate use of statistical methods based on actual data and the reasonable explanation for statistical results.This textbook combines statistical methods with the common application of SPSS software, which is flexible, convenient, and user-friendly; thus, students can focus on the deep understanding of statistics.The authors emphasize the application and generalization of statistical methods, and combine these methods with the modern statistical theory, such as sequential contingency table and multivariate statistical modelling, etc.This book is a useful textbook for graduate and undergraduate students in medical schools, including MBBS (Bachelor of Medicine and Bachelor of Surgery) student.
A Textbook on Ordinary Differential Equations (UNITEXT #73)
by Shair Ahmad Antonio AmbrosettiThe book is a primer of the theory of Ordinary Differential Equations. Each chapter is completed by a broad set of exercises; the reader will also find a set of solutions of selected exercises. The book contains many interesting examples as well (like the equations for the electric circuits, the pendulum equation, the logistic equation, the Lotka-Volterra system, and many other) which introduce the reader to some interesting aspects of the theory and its applications. The work is mainly addressed to students of Mathematics, Physics, Engineering, Statistics, Computer Sciences, with knowledge of Calculus and Linear Algebra, and contains more advanced topics for further developments, such as Laplace transform; Stability theory and existence of solutions to Boundary Value problems. A complete Solutions Manual, containing solutions to all the exercises published in the book, is available. Instructors who wish to adopt the book may request the manual by writing directly to one of the authors.
Textbook on Ordinary Differential Equations: A Theoretical Approach
by Ramakanta MeherMany scientific and real-world problems that occur in science, engineering, and medicine can be represented in differential equations. There is a vital role for differential equations in studying the behavior of different types of real-world problems. Thus, it becomes crucial to know the existence and uniqueness properties of differential equations and various methods of finding differential equation solutions in explicit form. It is also essential to know different kinds of differential equations in terms of eigenvalues, termed eigenvalue problems, and some special functions used in finding the solution to differential equations. The study of nonlinear problems also plays a significant role in different real-world situations. There is a necessity to know the behavior of solutions of nonlinear differential equations. Still, there are very few forms of differential equations whose solution can be found in explicit form. For the differential equations whose solutions cannot be found in explicit form, one has to study the properties of solutions of the given differential equation to guess an approximate solution of it. This book aims to introduce all the necessary topics of differential equations in one book so that laymen can easily understand the subject and apply it in their research areas. The novel approach used in this book is the introduction of different analytical methods for finding the solution of differential equations with sufficient theorems, corollaries, and examples, and the geometrical interpretations in each topic. This textbook is intended to study the theory and methods of finding the explicit solutions to differential equations, wherever possible, and in the absence of finding explicit solutions, it is intended to study the properties of solutions to the given differential equations. This book is based on syllabi of the theory of differential equations prescribed for postgraduate students of mathematics and applied mathematics in different institutions and universities of India and abroad. This book will be helpful for competitive examinations as well.
Textile Engineering: Statistical Techniques, Design of Experiments and Stochastic Modeling
by Anindya Ghosh Bapi Saha Prithwiraj MalFocusing on the importance of the application of statistical techniques, this book covers the design of experiments and stochastic modeling in textile engineering. Textile Engineering: Statistical Techniques, Design of Experiments and Stochastic Modeling focuses on the analysis and interpretation of textile data for improving the quality of textile processes and products using various statistical techniques. FEATURES Explores probability, random variables, probability distribution, estimation, significance test, ANOVA, acceptance sampling, control chart, regression and correlation, design of experiments and stochastic modeling pertaining to textiles Presents step-by-step mathematical derivations Includes MATLAB® codes for solving various numerical problems Consists of case studies, practical examples and homework problems in each chapter This book is aimed at graduate students, researchers and professionals in textile engineering, textile clothing, textile management and industrial engineering. This book is equally useful for learners and practitioners in other science and technological domains.
Textual Data Science with R (Chapman & Hall/CRC Computer Science & Data Analysis)
by Mónica Bécue-BertautTextual Statistics with R comprehensively covers the main multidimensional methods in textual statistics supported by a specially-written package in R. Methods discussed include correspondence analysis, clustering, and multiple factor analysis for contigency tables. Each method is illuminated by applications. The book is aimed at researchers and students in statistics, social sciences, hiistory, literature and linguistics. The book will be of interest to anyone from practitioners needing to extract information from texts to students in the field of massive data, where the ability to process textual data is becoming essential.
Textual Emotion Classification Using Deep Broad Learning (Socio-Affective Computing #11)
by Sancheng Peng Lihong CaoIn this book, the authors systematically and comprehensively discuss textual emotion classification by using deep broad learning. Since broad learning possesses certain advantages such as simple network structure, short training time and strong generalization ability, it is a new and promising framework for textual emotion classification in artificial intelligence. As a result, how to combine deep and broad learning has become a new trend of textual emotion classification, a booming topic in both academia and industry. For a better understanding, both quantitative and qualitative results are present in figures, tables, or other suitable formats to give the readers the broad picture of this topic along with unique insights of common sense and technical details, and to pave a solid ground for their forthcoming research or industry applications. In a progressive manner, the readers will gain exclusive knowledge in textual emotion classification using deep broad learning and be inspired to further investigate this underexplored domain. With no other similar book existing in the literature, the authors aim to make the book self-contained for newcomers, only a few prerequisites being expected from the readers. The book is meant as a reference for senior undergraduates, postgraduates, scientists and researchers interested to have a quick idea of the foundations and research progress of security and privacy in federated learning, and it can equally well be used as a textbook by lecturers, tutors, and undergraduates.
Texture Spaces (Studies in Fuzziness and Soft Computing #411)
by Murat DikerThis book provides a complete framework for the fundamental concepts and results of texture spaces and its applications. The principal aim is to present a comprehensive arguments due to connections among the textures, fuzzy sets and rough sets. In this context, direlations, fuzzy direlations and fuzzy relations constitute a bridge for the remarkable observations on rough set theory. In a more general setting, the approximation operators are also inspected for fuzzy rough set models with two domains of discourse. Since the book is self-contained and reader-friendly, the respected researchers may utilize this source for further investigations of the necessary results for their studies on rough set theory using textures. Therefore, prospective readers are not only mathematicians who interest in purely mathematical theories related to textures, but also engineers of information sciences who need more information for their interdisciplinary studies with respect to rough sets and fuzzy sets.
TGAU CBAC Canllaw Adolygu Mathemateg Canolradd
by Gareth Cole Keith Pledger Joe PetranExam Board: WJECLevel: GCSESubject: MathematicsFirst Teaching: September 2015First Exam: June 2017Maximise your students' grade potential with a step-by-step approach that builds confidence through topic summaries, worked examples and exam-style questions; developed specifically for the new Mathematics specifications, with leading Assessment Consultant Keith Pledger.- Identify areas of improvement to focus on through diagnostic tests for each topic.- Develop exam skills and techniques with skills-focused exam-style questions and exam advice on common pitfalls.- Build understanding and confidence with clear explanations of each topic covering all the key information needed to succeed.- Consolidate revision with 'two weeks to go' summaries for each topic.
TGAU CBAC Canllaw Adolygu Mathemateg Canolradd
by Keith Pledger Joe Petran Gareth ColeExam Board: WJECLevel: GCSESubject: MathematicsFirst Teaching: September 2015First Exam: June 2017Maximise your students' grade potential with a step-by-step approach that builds confidence through topic summaries, worked examples and exam-style questions; developed specifically for the new Mathematics specifications, with leading Assessment Consultant Keith Pledger.- Identify areas of improvement to focus on through diagnostic tests for each topic.- Develop exam skills and techniques with skills-focused exam-style questions and exam advice on common pitfalls.- Build understanding and confidence with clear explanations of each topic covering all the key information needed to succeed.- Consolidate revision with 'two weeks to go' summaries for each topic.
TGAU CBAC Canllaw Adolygu Mathemateg Sylfaenol (Welsh-language edition)
by Gareth Cole Keith Pledger Joe PetranExam Board: WJECLevel: GCSESubject: MathematicsFirst Teaching: September 2015First Exam: June 2017Maximise your students' grade potential with a step-by-step approach that builds confidence through topic summaries, worked examples and exam style questions- Identify areas of improvement to focus on through diagnostic tests for each topic.- Develop exam skills and techniques with skills-focused exam-style questions and exam advice on common pitfalls.- Build understanding and confidence with clear explanations of each topic covering all the key information needed to succeed.- Consolidate revision with 'two weeks to go' summaries for each topic.
TGAU CBAC Canllaw Adolygu Mathemateg Sylfaenol (Welsh-language edition)
by Keith Pledger Joe Petran Gareth ColeExam Board: WJECLevel: GCSESubject: MathematicsFirst Teaching: September 2015First Exam: June 2017Maximise your students' grade potential with a step-by-step approach that builds confidence through topic summaries, worked examples and exam style questions- Identify areas of improvement to focus on through diagnostic tests for each topic.- Develop exam skills and techniques with skills-focused exam-style questions and exam advice on common pitfalls.- Build understanding and confidence with clear explanations of each topic covering all the key information needed to succeed.- Consolidate revision with 'two weeks to go' summaries for each topic.
TGAU CBAC Canllaw Adolygu Mathemateg Uwch (WJEC GCSE Maths Higher: Mastering Mathematics Revision Guide Welsh-language edition)
by Gareth Cole Keith Pledger Joe PetranExam Board: WJECLevel: GCSESubject: MathematicsFirst Teaching: September 2015First Exam: June 2017Welsh language edition. Maximise your students' grade potential with a step-by-step approach that builds confidence through topic summaries, worked examples and exam style questions.- Identify areas of improvement to focus on through diagnostic tests for each topic.- Develop exam skills and techniques with skills-focused exam-style questions and exam advice on common pitfalls.- Build understanding and confidence with clear explanations of each topic covering all the key information needed to succeed.- Consolidate revision with 'two weeks to go' summaries for each topic.
TGAU CBAC Canllaw Adolygu Mathemateg Uwch (WJEC GCSE Maths Higher: Mastering Mathematics Revision Guide Welsh-language edition)
by Keith Pledger Joe Petran Gareth ColeExam Board: WJECLevel: GCSESubject: MathematicsFirst Teaching: September 2015First Exam: June 2017Welsh language edition. Maximise your students' grade potential with a step-by-step approach that builds confidence through topic summaries, worked examples and exam style questions.- Identify areas of improvement to focus on through diagnostic tests for each topic.- Develop exam skills and techniques with skills-focused exam-style questions and exam advice on common pitfalls.- Build understanding and confidence with clear explanations of each topic covering all the key information needed to succeed.- Consolidate revision with 'two weeks to go' summaries for each topic.
That Floating Bridge
by Benj DeMottAlive to history in the making (and the weight of the past) this volume examines Obama's presidency and Lyndon Johnson's, the killing of Trayvon Martin and the death of Andrew Breitbart, Occupy Wall Street and "America Beyond Capitalism." It presents essays, poems, and plays that speak to our times and challenge the liberal imagination. The title, That Floating Bridge, evokes Representative John Lewis' line "Obama is what comes at the end of that bridge in Selma" as it quotes a track on Gregg Allman's Low Country Blues, which Scott Spencer lauds here in a review for the Ages.That Floating Bridge's peerless range of contributors includes Amiri Baraka, Gar Alperovitz, Bernard Avishai, Uri Avnery, Bill Ayers, Paul Berman, John Chernoff, Mark Dudzic, Carmelita Estrellita, Henry Farrell, Fr. Rick Frechette, Donna Gaines, David Golding, Eugene Goodheart, Lawrence Goodwyn, Lisa Guenther, Alec Harrington, Malcolm Harris, Casey Hayden, Christopher Hayes, Patterson Hood, Roxane Johnson, Ben Kessler, Bob Levin, Philip Levine, Bongani Madondo, Greil Marcus, Scott McLemee, Judy Oppenheimer, Jedediah Purdy, Nick Salvatore, Aram Saroyan, Tom Smucker, Fredric Smoler, Violet Socks, A. B. Spellman, Scott Spencer, Richard Torres, Jesmyn Ward, and Pablo Yglesias.An account of how Franz Boas "did more to combat race prejudice than any other person" anchorsone section, but the volume also addresses devolutions of "diversity" linked with careerism in the art world and academe. An un-scholastic section titled "Criticism of Life"celebrates older and younger critics/poets. Songs are key to this volume's good times. Music writing ranging from Eddie Hinton's Very Extremely Dangerous to Berlioz's Romeo and Juliet enhances the pleasures of this text.
THE 2000 CENSUS: Interim Assessment
by Panel to Review the 2000 CensusThis volume contains the full text of two reports: one is an interim review of major census operations, which also assesses the U.S. Census bureau's recommendation in March 2001 regarding statistical adjustment of census data for redistricting. It does not address the decision on adjustment for non-redistricting purposes. <P><P>The second report consists of a letter sent to William Barron, acting director of the Census Bureau. It reviews the new set of evaluations prepared by the Census Bureau in support of its October decision. The two reports are packaged together to provide a unified discussion of statistical adjustment and other aspects of the 2000 census that the authoring panel has considered to date.
THE 2000 CENSUS: Counting Under Adversity
by Panel to Review the 2000 CensusThe decennial census was the federal government’s largest and most complex peacetime operation. This report of a panel of the National Research Council's Committee on National Statistics comprehensively reviews the conduct of the 2000 census and the quality of the resulting data. The panel's findings cover the planning process for 2000, which was marked by an atmosphere of intense controversy about the proposed role of statistical techniques in the census enumeration and possible adjustment for errors in counting the population. <P><P>The report addresses the success and problems of major innovations in census operations, the completeness of population coverage in 2000, and the quality of both the basic demographic data collected from all census respondents and the detailed socioeconomic data collected from the census long-form sample (about one-sixth of the population). The panel draws comparisons with the 1990 experience and recommends improvements in the planning process and design for 2010. <P><P>The 2000 Census: Counting Under Adversity will be an invaluable resource for users of the 2000 data and for policymakers and census planners. It provides a trove of information about the issues that have fueled debate about the census process and about the operations and quality of the nation's twenty-second decennial enumeration.
THE SECRET LIFE OF NUMBERS: 50 Easy Pieces on How Mathematicians Work and Think
by George G. SzpiroMost of us picture mathematicians laboring before a chalkboard, scribbling numbers and obscure symbols as they mutter unintelligibly. This lighthearted (but realistic) sneak-peak into the everyday world of mathematicians turns that stereotype on its head.Most people have little idea what mathematicians do or how they think. It’s often difficult to see how their seemingly arcane and esoteric work applies to our own everyday lives. But mathematics also holds a special allure for many people. We are drawn to its inherent beauty and fascinated by its complexity—but often intimidated by its presumed difficulty. The Secret Life of Numbers opens our eyes to the joys of mathematics, introducing us to the charming, often whimsical side, of the discipline. Divided into several parts, the book looks at interesting and largely unknown historical tidbits, introduces the largerthan- life practitioners of mathematics through the ages, profiles some of the most significant unsolved conjectures, and describes problems and puzzles that have already been solved. Rounding out the table of contents is a host of mathematical miscellany—all of which add up to 50 fun, sometimes cheeky, shorttakes on the field. Chock full of stories, anecdotes, and entertaining vignettes, The Secret Life of Numbers shows us how mathematics really does affect almost every aspect of life—from the law to geography, elections to botany—and we come to appreciate the delight and gratification that mathematics holds for all of us.
The Theft of a Decade: How the Baby Boomers Stole the Millennials' Economic Future
by Joseph C. SternbergA Wall Street Journal columnist delivers a brilliant narrative of the mugging of the millennial generation-- how the Baby Boomers have stolen the millennials' future in order to ensure themselves a comfortable presentThe Theft of a Decade is a contrarian, revelatory analysis of how one generation pulled the rug out from under another, and the myriad consequences that has set in store for all of us. The millennial generation was the unfortunate victim of several generations of economic theories that made life harder for them than it was for their grandparents. Then came the crash of 2008, and the Boomer generation's reaction to it was brutal: politicians and policy makers made deliberate decisions that favored the interests of the Boomer generation over their heirs, the most egregious being over the use of monetary policy, fiscal policy and regulation. For the first time in recent history, policy makers gave up on investing for the future and instead mortgaged that future to pay for the ugly economic sins of the present. This book describes a new economic crisis, a sinister tectonic shift that is stealing a generation's future.
Their Arrows Will Darken the Sun: The Evolution and Science of Ballistics
by Mark DennyThe science of ballistics has a long history and starts with one question: How does a projectile move through the air? Even before physicists worked that one out, military engineers had been tinkering with ballistic devices for centuries. The trebuchet of the Middle Ages has given way to rocket power, and the science of ballistics has evolved to match the technology. Mark Denny’s survey covers this dynamic subject from prehistory to the weapons of tomorrow.Taking the bang-whiz-thud approach, Denny first talks about internal ballistics—Bang!—from before gunpowder to the development of modern firearms. External ballistics—Whiz!—are next, with discussions about short- and long-range trajectories. Denny’s lesson ends with a Thud!—an explanation of terminal ballistics. Throughout, Denny conveys applicable physics principles in a way that will appeal to technology buffs and ballistics enthusiasts alike. His fun and factual explanations are free of complicated equations; notes cover the key aspects of ballistics physics for the more technically inclined. Denny has perfected this engaging balance of science and story. For study or hobby, Their Arrows Will Darken the Sun is an entertaining guide to the world of ballistics.
Themes from Weir: A Celebration of the Philosophy of Alan Weir (Synthese Library #484)
by Adam Rieger Stephan LeuenbergerThis book celebrates and explores some philosophical issues raised by the work of Alan Weir, who is Professor Emeritus at the University of Glasgow, having previously held positions at the Universities of Oxford, Edinburgh and Queen’s, Belfast. In a number of areas, Weir has elaborated strikingly original views which involve a radical departure from the mainstream. These include formalism in the philosophy of mathematics, and as well as naïve set theory, with a universal set, and a naïve theory of truth. In contrast to other contemporary defenders of the latter two theories, Weir rejects dialetheism and accepts classical rules for the logical connectives. He avoids contradictions by restricting certain structural inference rules, specifically some generalized versions of transitivity. In addition, Weir has developed radical versions of naturalism and physicalism (partly informed by his work on Quine) and perceptual realism. This collection includes contributions by a distinguished group of philosophers on Weir’s philosophy, as well as a memoir and a new essay on the philosophy of mathematics by Weir himself.
Themes in Economic Analysis: Theory, policy and measurement
by Subrata Guha Rajendra Prasad Kundu S. SubramanianThis book covers diverse themes, including institutions and efficiency, choice and values, law and economics, development and policy, and social and economic measurement. Written in honour of the distinguished economist Satish K. Jain, this compilation of essays should appeal not only to students and researchers of economic theory but also to those interested in the design and evaluation of institutions and policy.