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Advanced Computational Intelligence in Healthcare-7: Biomedical Informatics (Studies in Computational Intelligence #891)
by Lakhmi C. Jain Sheryl Brahnam Ilias MaglogiannisThis book presents state-of-the-art works and systematic reviews in the emerging field of computational intelligence (CI) in electronic health care. The respective chapters present surveys and practical examples of artificial intelligence applications in the areas of Human-Machine Interface (HMI) and affective computing, machine learning, big health data and visualization analytics, computer vision and medical image analysis. The book also addresses new and emerging topics in CI for health care such as the utilization of Social Media (SM) and the introduction of new intelligent paradigms in the security and privacy domains, which are critical for the health sector. The chapters, while of course not exhaustively addressing all the possible aspects of the aforementioned areas, are indicative of the dynamic nature of interdisciplinary research being pursued. Accordingly, the book is intended not only for researchers in the respective fields, but also for medical and administrative personnel working in the health sector, as well as managers and stakeholders responsible for making strategic decisions and defining public health policies.
Advanced Computational Intelligence Techniques for Virtual Reality in Healthcare (Studies in Computational Intelligence #875)
by Aboul Ella Hassanien Deepak Gupta Ashish KhannaThis book addresses the difficult task of integrating computational techniques with virtual reality and healthcare. It discusses the use of virtual reality in various areas, such as healthcare, cognitive and behavioural training, understanding mathematical graphs, human–computer interaction, fluid dynamics in healthcare industries, accurate real-time simulation, and healthcare diagnostics.Presenting the computational techniques for virtual reality in healthcare, it is a valuable reference resource for professionals at educational institutes as well as researchers, scientists, engineers and practitioners in industry.
Advanced Computational Methods in Life System Modeling and Simulation: International Conference on Life System Modeling and Simulation, LSMS 2017 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2017, Nanjing, China, September 22-24, 2017, Proceedings, Part I (Communications in Computer and Information Science #761)
by Xin Li Xin Sun Zhou Su Minrui Fei Shiwei Ma Li JiaThe three-volume set CCIS 761, CCIS 762, and CCIS 763 constitutes the thoroughly refereed proceedings of the International Conference on Life System Modeling and Simulation, LSMS 2017, and of the International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2017, held in Nanjing, China, in September 2017. The 208 revised full papers presented were carefully reviewed and selected from over 625 submissions. The papers of this volume are organized in topical sections on: Biomedical Signal Processing; Computational Methods in Organism Modeling; Medical Apparatus and Clinical Applications; Bionics Control Methods, Algorithms and Apparatus; Modeling and Simulation of Life Systems; Data Driven Analysis; Image and Video Processing; Advanced Fuzzy and Neural Network Theory and Algorithms; Advanced Evolutionary Methods and Applications; Advanced Machine Learning Methods and Applications; Intelligent Modeling, Monitoring, and Control of Complex Nonlinear Systems; Advanced Methods for Networked Systems; Control and Analysis of Transportation Systems; Advanced Sliding Mode Control and Applications; Advanced Analysis of New Materials and Devices; Computational Intelligence in Utilization of Clean and Renewable Energy Resources; Intelligent Methods for Energy Saving and Pollution Reduction; Intelligent Methods in Developing Electric Vehicles, Engines and Equipment; Intelligent Computing and Control in Power Systems; Modeling, Simulation and Control in Smart Grid and Microgrid; Optimization Methods; Computational Methods for Sustainable Environment.
Advanced Concepts in Human Immunology: Prospects For Disease Control
by Pooja Jain Lishomwa C. NdhlovuThis book highlights information derived primarily from clinical samples, with particular reference to theoretical and scientific aspects of the human immune system. This text will focus on topics that range from host-pathogen interactions in infectious disease to host immune response in cancer, allergic diseases, neuroinflammatory diseases, and autoimmune disorders. The reader will also have a well-rounded understanding of the behavior of the immune system with particular emphasis on the role of immunoproteomics in immunotherapy, neuroprotective immunity for neurodegenerative and neuroinfectious disease, leukemia-associated dendritic cell induction of adaptive immunity dysregulation, and the role of immune checkpoint inhibitors in cancer, infection, as well as neuroinflammation. Taken together, the contents of this book are intended for both clinicians and researchers in academia and industry.
Advanced Concepts in Lumbar Degenerative Disk Disease
by H. Michael Mayer João Luiz Pinheiro-Franco Alexander R. Vaccaro Edward C. BenzelIn this book, leading international specialists in the field join forces to discuss topics, issues and approaches that are of key importance in the optimal treatment of lumbar degenerative disk disease. The coverage is wide ranging, from current understanding of physiopathology and genetics and modern imaging techniques through to the diverse minimally invasive, non-fusion, and fusion surgical techniques. Detailed attention is drawn to the most important aspects to be considered when approaching the patient and making treatment decisions. The role of conservative management is appraised, and surgical techniques and their indications are carefully described. In the concluding section, some of the top specialists from across the world reflect on the lessons that they have learned during lifetimes in spinal surgery. Advanced Concepts in Lumbar Degenerative Disk Disease will be an instructive and fascinating source of information for all spine surgeons and other spine care providers.
Advanced Consulting in Family Medicine: The Consultation Expertise Model (Radcliffe Ser.)
by Peter Worrall Adrian French Les AshtonWhat distinguishes the consulting of experienced family doctors from their newly qualified colleagues? The question is often frustratingly hard answer clearly or objectively: unlike many professions, family doctors face a dearth of clear expectations of what constitutes advanced practice, a lack of defined standards against which to evaluate it, and an absence of expertise-related professional training in which to develop it post-certification. The model of consultation excellence outlined in this book illustrates in practical terms how advanced consulting can be nurtured. It avoids tantalising value judgement such as 'excellence'. Instead, it describes behaviours in terms that can be observed day to day, providing a detailed picture of what constitutes advanced consulting behaviour, how family doctors can be helped to acquire these higher levels of expertise, and how changes in behaviour can be identified and evaluated. "Advanced Consulting in Family Medicine" is written in handbook form for easy access and use, and provides a vital vision of higher order family doctor consulting.
Advanced Cosmetic Otoplasty: Art, Science, and New Clinical Techniques
by Melvin A. ShiffmanIn this book, international experts present up-to-date techniques of otoplasty in which they have extensive personal experience. Both new and modified procedures are described with the aid of a wealth of high-quality illustrations. In addition to these detailed descriptions, ear embryology and anatomy, psychological issues, postoperative care, possible risks and complications, and outcomes are extensively covered in order to provide the reader with a state of the art account of all aspects of cosmetic otoplasty. Throughout, the contributors are inventive and eloquent in guiding the reader to a better understanding that optimal results of otoplasty will be achieved only with a more refined approach than the routine use of simplified techniques. This book will be of value to both students (residents and fellows) and experienced cosmetic, plastic, maxillofacial, and general surgeons.
Advanced Data Analysis in Neuroscience: Integrating Statistical and Computational Models (Bernstein Series in Computational Neuroscience)
by Daniel DurstewitzThis book is intended for use in advanced graduate courses in statistics / machine learning, as well as for all experimental neuroscientists seeking to understand statistical methods at a deeper level, and theoretical neuroscientists with a limited background in statistics. It reviews almost all areas of applied statistics, from basic statistical estimation and test theory, linear and nonlinear approaches for regression and classification, to model selection and methods for dimensionality reduction, density estimation and unsupervised clustering. Its focus, however, is linear and nonlinear time series analysis from a dynamical systems perspective, based on which it aims to convey an understanding also of the dynamical mechanisms that could have generated observed time series. Further, it integrates computational modeling of behavioral and neural dynamics with statistical estimation and hypothesis testing. This way computational models in neuroscience are not only explanat ory frameworks, but become powerful, quantitative data-analytical tools in themselves that enable researchers to look beyond the data surface and unravel underlying mechanisms. Interactive examples of most methods are provided through a package of MatLab routines, encouraging a playful approach to the subject, and providing readers with a better feel for the practical aspects of the methods covered. "Computational neuroscience is essential for integrating and providing a basis for understanding the myriads of remarkable laboratory data on nervous system functions. Daniel Durstewitz has excellently covered the breadth of computational neuroscience from statistical interpretations of data to biophysically based modeling of the neurobiological sources of those data. His presentation is clear, pedagogically sound, and readily useable by experts and beginners alike. It is a pleasure to recommend this very well crafted discussion to experimental neuroscientists as well as mathematically well versed Physicists. The book acts as a window to the issues, to the questions, and to the tools for finding the answers to interesting inquiries about brains and how they function. " Henry D. I. Abarbanel Physics and Scripps Institution of Oceanography, University of California, San Diego "This book delivers a clear and thorough introduction to sophisticated analysis approaches useful in computational neuroscience. The models described and the examples provided will help readers develop critical intuitions into what the methods reveal about data. The overall approach of the book reflects the extensive experience Prof. Durstewitz has developed as a leading practitioner of computational neuroscience. " Bruno B. Averbeck
Advanced Decision Making Methods Applied to Health Care (International Series in Operations Research & Management Science #173)
by Angela Testi Elena TanfaniThe most difficult part of making decisions in the health care field on all levels (national, regional, institutional, patient) is linked to the very complexity of the system itself, to the intrinsic uncertainty involved and its dynamic nature. This requires not only the ability to analyze and interpret a large amount of information but also arrange it so that it becomes a cognitive base for appropriate decision-making. Moreover, decisions in the health care field are subjected to many challenges and constraints: fast change and uncertain outcomes, aging population, increasing citizen expectations, equity considerations and limited resources. Operations research, statistical and economic-related quantitative methods supply these decisions making tools and methodology. The contributed book presents a collection of applications to concrete situations detailing the problem area, the methodology employed, the implementation and results. Each topic addressed in the book will be structured in such a way that an interdisciplinary and wide audience will be able to use the materials presented. As an example the book chapters will address health policies issues, planning health services, epidemiology and disease modelling, home-care modelling, logistics in health care, capacity planning, quality and appropriateness.
Advanced Dental Metallic Materials (Springer Series in Materials Science #338)
by Rebeka Rudolf Peter Majerič Vojkan Lazić Karlo T. RaićThis book delivers a broad and concise look at advanced metallic materials used for dental applications. Due to their excellent mechanical and biological properties, the use of metallic materials in dentistry has continued since time immemorial. In that sense, this book aims to bring the readers closer to the specific purpose of dental metallic materials meeting specific criteria and materials properties such as biocompatibility, non-toxicity, resistance to corrosion, long-term durability, appropriate strength and toughness, as well as corresponding values of modulus of elasticity. Following a comprehensive introduction to the field, the book discusses topical issues such as the long-term stability of dental titanium implants, processing of cobalt-chrome dental alloys, emerging gold dental alloys, and novel nanofoils used for dental joining. Featuring numerous illustrative examples of experimental outcomes, this book is an ideal resource for materials scientists and metallurgists working on advanced alloys for dental applications.
Advanced Drug Delivery
by Ashim Mitra Chi H. Lee Kun ChengProvides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.
Advanced Drug Delivery: Methods and Applications (Studies in Mechanobiology, Tissue Engineering and Biomaterials #26)
by Tuhin Subhra Santra Ashwini Uma Surendra ShindeThis book provides an overview of various drug delivery systems at the cellular level including biological, chemical methods, and most importantly physical methods such as photoporation, electroporation, mechanoporation, and device-based techniques (e.g., microfluidics), as well as organism-level techniques including nanomaterials, biomaterials, and transdermal. Drug delivery (DD) can be defined as the method and route by which an active pharmaceutical ingredient (API) is administered to promote its desired pharmacological effect and/or convenience and/or to reduce adverse effects. Drug delivery systems are developed to maximize drug efficacy and minimize side effects. As drug delivery technologies improve, the drug becomes safer and more comfortable for patients to use. During the last seven decades, extraordinary progress has been made in drug delivery technologies, such as systems for long-term delivery for months and years, localized delivery, and targeted delivery. The advances, however, will face the next phase considering the future technologies that we need to overcome many physicochemical barriers for new formulation development and biological unknowns for treating various diseases. Thus, various technologies are built at a single-cell level as well as an organism level. This book is useful at the university level for graduate courses or research studies and biotechnology-based companies with research and development on cell-based analysis, diagnosis, or drug screening. This book is also very useful for researchers in drug delivery technologies, which came in frontier research for the past decade.
Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases
by Dinesh Kumar Chellappan Kavita Pabreja Md. FaiyazuddinThis book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.
Advanced Drug Formulation Design to Optimize Therapeutic Outcomes (Drugs and the Pharmaceutical Sciences)
by Robert O. Williams III David R. Taft Jason T. McConvilleThis title demonstrates how advanced formulation designs and delivery technologies can be used to improve drug efficacy and treatment outcomes in particular therapeutic categories or disease states. It discusses nanoparticle systems for cancer treatments, and also presents cutting edge immono-regulation agents for transplantation and the local targ
Advanced Electroencephalography Analytical Methods: Fundamentals, Acquisition, and Applications (Biomedical Signal and Image Processing)
by Ganesh Naik Santos, Wellington Pinheiro dos Gaetano GargiuloAdvanced Electroencephalography Analytical Methods: Fundamentals, Acquisition, and Applications presents the theoretical basis and applications of electroencephalography (EEG) signals in neuroscience, involving signal analysis, processing, signal acquisition, representation, and applications of EEG signal analysis using non-linear approaches and machine learning. It explains principles of neurophysiology, linear signal processing, computational intelligence, and the nature of signals including machine learning. Applications involve computer-aided diagnosis, brain-computer interfaces, rehabilitation engineering, and applied neuroscience.This book: Includes a comprehensive review on biomedical signals nature and acquisition aspects. Focuses on selected applications of neuroscience/cardiovascular/muscle-related biomedical areas. Provides a machine learning update to a classical biomedical signal processing approach. Explains deep learning and application to biomedical signal processing and analysis. Explores relevant biomedical engineering and neuroscience state-of-the-art applications. This book is intended for researchers and graduate students in biomedical signal processing, electrical engineering, neuroscience, and computer science.
Advanced Electroporation Techniques in Biology and Medicine (Biological Effects of Electromagnetics)
by Andrei G. Pakhomov Damijan Miklavcic Marko S. MarkovA reflection of the intense study of the effects of electromagnetic fields on living tissues that has taken place during the last decades, Advanced Electroporation Techniques in Biology and Medicine summarizes most recent experimental findings and theories related to permeabilization of biomembranes by pulsed electric fields. Edited by experts and
Advanced ENT MCQs: Training to pass the FRCS (ORL-HNS) Part 1 (MasterPass)
by Peter Kullar Jameel Muzaffar Joseph ManjalyProviding over 400 high quality MCQs in the style of the Part 1 FRCS (ORL-HNS) together with clear explanations of not only the correct answer but also a structured way of approaching questions, this revision guide enables exam candidates to prepare for the FRCS (ORL-HNS) Section 1 exam with confidence.The questions and answers reflect the new approach to the exam and its focus on higher order judgement and testing real world clinical decision making. Questions are presented as a common stem with five possible answers, one of which will be the most correct answer: a ‘single best answer’. The stem is carefully written, so that every word should help guide candidates to the correct answer. None of the answers will be obviously wrong or dangerous. The candidate must recognise that a ‘single best answer’ is not the same as a ‘single correct answer’. In many of the questions, all the presented answers could be considered correct, but the candidate must choose the best or most appropriate answer from those available.Written by an expert author team who have provided valuable insights and expert content to ensure the book’s authority. The content is suitable for exam candidates from the UK and for International ENT trainees preparing to sit the FRCS (ORL-HNS) exam. It is also applicable for candidates preparing for the DOHNS/MRCS ENT exam.
Advanced ENT training: A guide to passing the FRCS (ORL-HNS) examination
by Joseph Manjaly Peter KullarThe syllabus for the FRCS (ORL-HNS) is vast and sound preparation for the exams has traditionally involved assimilatiing knowledge from a wide range of sources. This book provides a focussed guide for exam candidates. More than a question and answer book, this book is a coaching manual. Each section features a combination of model answers, pearls of wisdom, checklists and pointers for further reading. Detailed advice is provided for both Part 1 and Part 2 of the examnation. Viva topics that have featured in the exam in recent years have been included. and have then been supplemented by invaluable editorial contributions from leaders in each of the subspecialties. Trainees frequently comment that exam preparation is an enlightening process and the knowledge gained would have served them well during their time as an ENT registrar or Otorhinolaryngology resident.This book will also serve as a valuable learning tool for trainees as early as ST3 and facilitate their development of effective and safe clinical practice.
Advanced ERCP for Complicated and Refractory Biliary and Pancreatic Diseases
by Dong Ki LeeThis book provides a comprehensive overview of non-surgical treatments for complicated and refractory biliary and pancreatic lesions. In particular, it offers non-surgical treatment options for benign biliary strictures. For those suffering from intractable total biliary obstruction following biliary operation, magnetic compression anastomosis represents a good therapeutic option, and this technique is fully explained. Moreover, the book describes diverse treatment modalities for hilar stricture, which is one of the most challenging areas of ERCP. Several chapters cover a variety of important aspects of this area. The book also aims to identify and solve the unmet needs for the diagnosis and treatment of biliary and pancreatic diseases. The precise explanations of treatment concepts and strategies will both increase readers’ knowledge and provide assistance in daily clinical practice. The authors are pioneering experts from around the world, and the text is supported by numerous informative illustrations and helpful summaries.
Advanced First Aid CPR + AED
by National Safety Council National Safety Council NscPart of a series of titles authored by the National Safety Council, First Aid: Taking Action covers the material required for a semester long Advanced First Aid course . The focus is teaching how to recognize and act in any emergency and to sustain life until professional help can arrive. Other information includes bleeding control, and first aid for sudden illnesses and injuries. Information is presented in a concise easy-to-read manner that works as a handy reference after the course. National Safety Council programs and products are designed to benefit all types of learning styles by combining lectures, video presentations, group discussions, and hands-on training.
Advanced Fitness Assessment and Exercise Prescription
by Ann L. Gibson Vivian H. HeywardThe text bridges the gap between research and practice and synthesizes concepts and theories from exercise physiology, kinesiology, measurement, psychology, and nutrition to provide a clearly defined approach to physical fitness testing and the design of individualized exercise programs.
Advanced Fluorescence Reporters in Chemistry and Biology I: Fundamentals and Molecular Design (Springer Series on Fluorescence #8)
by Alexander P. DemchenkoThis volume is focused on one of the most important challenges in sensing and imaging technologies: the design of fluorescence reporters with advanced properties. Here organic dyes occupy leading positions, in tough competition with novel materials such as metal chelating complexes and semiconductor nanoparticles. 11 chapters written by top experts in the field show new possibilities in the design of organic dyes as fluorescent labels and reporters. They particularly highlight the progress that has been made in enhancing the response to intermolecular interactions and their excited-state reaction dynamics (intramolecular charge and proton transfers), and on the development of dyes with strong two-photon absorption and emitting in the near-IR region. Furthermore, fluorophores incorporated into new members of the green fluorescent protein family, an invaluable tool for live cell imaging, are examined.
Advanced Fluorescence Reporters in Chemistry and Biology II: Molecular Constructions, Polymers and Nanoparticles (Springer Series on Fluorescence #9)
by Alexander P. DemchenkoThis volume demonstrates the novel possibilities in sensing and imaging offered by the assembly of organic dyes into nanoparticles and nanocomposites and by the application of strongly fluorescent noble metal clusters and conjugated polymers. Its 14 chapters, written by top experts in this field, provide in-depth information on the coupling of organic dyes to different molecular and supramolecular structures, on their incorporation into polymeric nanoparticles and on the nanostructures that can be formed by some of the dyes. Bright and photostable several-atom clusters of gold and silver are examined. Finally, the revolutionary changes in sensing technologies attending the advent of conjugated polmyers and the advances in their application are discussed.
Advanced Fluorescence Reporters in Chemistry and Biology III: Applications in Sensing and Imaging (Springer Series on Fluorescence #10)
by Alexander P. DemchenkoThe key element of any fluorescence sensing or imaging technology is the fluorescence reporter, which transforms the information on molecular interactions and dynamics into measurable signals of fluorescence emission. This book, written by a team of frontline researchers, demonstrates the broad field of applications of fluorescence reporters, starting from nanoscopic properties of materials, such as self-assembled thin films, polymers and ionic liquids, through biological macromolecules and further to living cell, tissue and body imaging. Basic information on obtaining and interpreting experimental data is presented and recent progress in these practically important areas is highlighted. The book is addressed to a broad interdisciplinary audience.
Advanced Functional Materials: Proceedings Of Chinese Materials Conference 2017 (Materials Science Forum Vol. 815 Ser.)
by Yafang HanThis proceedings volume gathers selected papers presented at the Chinese Materials Conference 2017 (CMC2017), held in Yinchuan City, Ningxia, China, on July 06-12, 2017.