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The Functional Roles of Histamine Receptors (Current Topics in Behavioral Neurosciences #59)
by Kazuhiko Yanai Maria Beatrice PassaniResearch in the field of histamine receptors over the past 100 years went hand-in-hand with the development of modern pharmacology. Advances in histamine research led by outstanding scientists was so incisive that the clinical approach to treat allergies and gastrointestinal ailments was revolutionized. The pharmacological treatment of peptic ulcer and gastroesophageal reflux was indeed a revolution, as it ended the surgical intervention. Interest in histamine pharmacology was resurrected by the discovery of another histamine receptor, number 4, using genomics-based reverse pharmacological approaches for screening orphan GPCRs. This receptor is preferentially expressed by immune cells and its discovery raised hopes for its translational exploitation as a new therapeutic target for unmet medical needs ranging from asthma to cancer. However, several drawbacks emerged and dramatically slowed down research in the field. A better understanding of receptor intra-and interspecies heterogeneity will certainly improve and accelerate the translation of experimental data into clinical practice. Also, the plethora of data on brain histamine is hinting at a fundamental role of this system as a hub that receives internal and peripheral stimuli to allocate the necessary excitation to specific brain circuits that preside the appropriate behavioral responses. The development of new histaminergic ligands is an ongoing process that constantly provide new preclinical tools. The aim of this book is to cover the most important aspects of histamine receptor function and pharmacology in the central nervous system and to provide a comprehensive overview of the preclinical and clinical advances made in recent decades and the exciting prospects for the future. It highlights the clinical areas where there is a great need for new therapeutic approaches and where novel histaminergic agents may be useful for personalized medicine.
Functional Selectivity of G Protein-Coupled Receptor Ligands
by Kim NeveFunctional selectivity refers to the ability of different ligands acting at one receptor subtype to activate multiple signaling pathways in unique combinations; that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at pathway B, and another drug can have the reverse profile. Functional selectivity has profound implications for drug development, for chemical biology, and for the design of experiments to characterize receptor function. In Functional Selectivity of G Protein-Coupled Receptors expert neuroscientists and pharmacologists review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon. This exciting, comprehensive, and future-oriented volume includes chapters that focus on theoretical and mechanistic aspects of functional selectivity and that cut across subfamilies of GPCRs. Additional chapters focus on subfamilies of therapeutically relevant receptors where there is considerable evidence of ligand functional selectivity. Accessible and authoritative, Functional Selectivity of G Protein-Coupled Receptors is a valuable educational tool and reference source for students and scientists interested in drug development, chemical biology, and GPCR function.
Functional Smart Nanomaterials and Their Theranostics Approaches (Smart Nanomaterials Technology)
by Alle Madhusudhan Shiv Dutt Purohit Rajendra Prasad Azamal HusenThis book covers a number of engineered nanotheranostics platforms and nanomedicines applications of FDA-approved medicines for early-stage diagnosis and treatment of cancer. The book focuses on (i) the basic design and bioengineering of safe medicines, (ii) physicochemical understanding of surface engineered medicines and their characteristics, (iii) various examples for site-specific bioimaging and multimode therapies, (iv) stimuli-responsive approaches for targeted drug delivery applications, (v) targeted therapeutics approaches for cancer cells or solid tumor ablations, (vi) targeted mechanisms of administrative biomedicines, (vii) impact of surface modification or engineering of biomedicines for site-selective tumor binding ability, and (vii) requirements for clinical trials and FDA approval. The content of this book appeal to readers who are interested in recent developments of FDA-approved cost-effective rapid cancer imaging and therapeutic platforms.
Functional Somatic Symptoms in Children and Adolescents: A Stress-System Approach to Assessment and Treatment (Palgrave Texts in Counselling and Psychotherapy)
by Stephen Scher Kasia Kozlowska Helene HelgelandThis open access book sets out the stress-system model for functional somatic symptoms in children and adolescents. The book begins by exploring the initial encounter between the paediatrician, child, and family, moves through the assessment process, including the formulation and the treatment contract, and then describes the various forms of treatment that are designed to settle the child’s dysregulated stress system. This approach both provides a new understanding of how such symptoms emerge – typically, through a history of recurrent or chronic stress, either physical or psychological – and points the way to effective assessment, management, and treatment that put the child (and family) back on the road to health and well-being.
Functional Symptoms in Pediatric Disease: A Clinical Guide
by Ran D. AnbarMany children with medical conditions fail to improve despite physicians' best efforts. Sometimes, we ascribe this failure to lack of adherence to therapy or to the severity of the condition. What we often fail to appreciate, however is that sometimes the lack of improvement can be explained by the patients' psychological states. The first section of Functional Symptoms in Pediatric Disease: A Clinical Guide teaches children's health care providers to recognize functional symptoms that can complicate organic disease as well as symptoms that are believed to be purely functional in origin. Literature reviews, case studies and quizzes are provided in each chapter, with video demonstrations included in some of the chapters. The second section of the book will help clinicians differentiate the patients for whom referral to a mental health provider is mandatory from those for whom other approaches may be useful. For the latter group, the book teaches clinicians to empower themselves by learning how to incorporate various therapies for functional disorders into their practice, including biofeedback, basic cognitive behavioral therapy techniques, hypnosis, acupressure, yoga and meditation. Practical strategies for obtaining training in these modalities are provided in the appendix. Useful for practicing clinicians including pediatricians, family practitioners, pediatric subspecialists, child psychiatrists, psychologists, other mental health care providers and practitioners of alternative and complementary medicine, Functional Symptoms in Pediatric Disease: A Clinical Guide is an important new book that will help children's health care providers consider the possible impact of functional contributions to the clinical presentation of their patients.
Functional Urologic Surgery in Neurogenic and Oncologic Diseases
by Antonio Carbone Giovanni Palleschi Antonio Luigi Pastore Aurel MessasThis book offers a comprehensive guide to state-of-the-art techniques in functional urologic surgery that minimize functional damage to the urinary tract and are of particular value in patients with oncologic or neurogenic diseases. It describes the main minimally invasive surgical techniques currently available step by step, while also offering guidance on indications and how to select appropriate surgical devices to achieve specific oncological and functional outcomes. Further, the book presents data from relevant case series, documenting the favorable functional and oncologic results achieved with these techniques and devices as well as the low associated morbidity and positive impacts on quality of life. Lastly, it offers advice on preoperative assessment and postoperative care, and presents specific diagnostic algorithms of value in daily clinical practice. The contributing authors represent an international mix of respected experts carefully selected for their knowledge of the topics discussed.
Functional Vision: A Practitioner's Guide To Evaluation And Intervention
by Amanda Hall LueckAn essential tool for anyone working in the area of low vision, Functional Vision presents a systematic, comprehensive, integrated approach to assessing an individuals functional vision and delivering the appropriate services determined by the assessment results. Based on groundbreaking work by distinguished professionals who have developed the specific principles and procedures for helping people of all ages with low vision, including those with multiple disabilities, the text explains how to link intervention to assessment findings and to teach compensatory skills through everyday activities at school, work, home, and in the community. This detailed and practical guide provides case examples, charts, figures, and sample forms that enable practitioners to apply expert methods in their work with clients
Functionalized Nanomaterials I: Fabrications
by Vineet Kumar Shivendu Ranjan Nandita Dasgupta Praveen GuleriaNanomaterials contain some unique properties compared to their bulk. Their unique properties are due to the chemical nature of the material, small size, and surface functionalization. Along with control over size, the functionalization of nanomaterials also affects their compatibility to the environment and living organisms. This book provides a detailed account of nanomaterials functionalization along with a brief overview of their application. This book serves as a reference for scientific investigators including doctoral and postdoctoral scholars and undergradate and graduate students who need to have knowledge of the basics of nanomaterial functionalization, recent advancements, challenges, and opportunities in this field. This book will also provide critical and comparative data for nano-technologists and may be beneficial for industry personnel, journalists, policy makers, and the general public to help understand functionalized nanomaterials in detail and in depth. Features: This book is comprehensive and covers all aspects of functionalized nanotechnology. It describes the challenges and methods of functionalized nanomaterials synthesis for different applications. It discusses the recent findings and cutting-edge global research trends on the functionalization of nanomaterials. It emphasizes the products and market, safety, and regulatory issues of functionalized nanomaterials. It contains contributions from international experts and will be a valuable resource for researchers.
Functionalized Nanomaterials II: Applications
by Vineet Kumar Praveen Guleria Nandita Dasgupta Shivendu RanjanThe functionalization of nanomaterials provides them with some unique properties, making the same nanomaterial amenable for various applications by simply manipulating functional components. However, functionalized nanomaterials also face some challenges, along with some encouraging new applications in the future. This book provides a detailed account of applications of the functionalization of nanomaterials. This book can serve as a reference book for scientific investigators, including doctoral and post-doctoral scholars and undergraduate and graduate students, in context with the scope of applications of functionalized nanomaterials. It also highlights recent advances, challenges, and opportunities in the application of nanomaterials. This book will provide critical and comparative data for nanotechnologists. It may also be beneficial for multidisciplinary researchers, industry personnel, journalists, policy makers, and the common public to understand the scope of functionalized nanomaterials in detail and in depth. Features: This book covers various applications of functionalized nanomaterials. It discusses recent global research trends and future applications of functionalized nanomaterials. It highlights the need for more rigorous regulatory frameworks for the safe use of functionalized nanomaterials. It contains contributions from international experts and will be a valuable resource for researchers.
Functionalized Smart Nanomaterials for Point-of-Care Testing (Smart Nanomaterials Technology)
by Amit Kumar Mandal Suvankar Ghorai Azamal HusenThis book highlights the recent advancement in point-of-care testing (POCT) technologies utilizing ‘smart’ nanomaterials for the analysis of biomarkers related to disease, which includes metabolites, enzymes, proteins, nucleic acids, cancer cells and multidrug-resistant pathogen. The POCT refers to medical diagnostic tests performed near the place and time of patient care. During the recent pandemic of COVID-19, many realized the importance of affordable, rapid and accurate POCT devices and their usefulness to combat the spread of the infection. The chapters in this book describe the emergence of ‘smart’ nanomaterials with unique physical and chemical properties being utilized in POCT devices for immobilizing biorecognition elements and labels for signal generation, transduction and amplification. It showcases the applications of these smart nanomaterials and their superiority in developing point-of-care diagnostics devices in a wide range of applied fields like food industry, agriculture sector, water quality assessment, pharmaceuticals and tissue engineering. It also looks into the challenges associated and future direction of research in this promising field. This book caters as reference book for researches from the field of nanobiotechnology and biomedical sciences who are interested in the development of rapid, affordable and accurate POCT devices.
Functioneren als focus van zorg en welzijn: Met ICF-praktijkvoorbeelden
by Yvonne Heerkens Gonda StallingaIn dit boek maakt de lezer kennis met een aantal nieuwe gezondheidsconcepten. Functioneren is het centrale thema en in het bijzonder wordt aandacht besteed aan de toepassingsmogelijkheden van de International Classification of Functioning, Disability and Health (ICF) van de WHO. De focus van gezondheidszorg is aan het verschuiven: van genezen van ziekten naar bevorderen van gezondheid en welzijn. Het dagelijks functioneren van mensen wordt centraal gesteld. Het is een beweging waarin het perspectief op gezondheid verbreedt van een beperkt (biomedisch) perspectief naar een meer holistisch (biopsychosociaal) perspectief. In dat perspectief, waarin het mee kunnen doen in de samenleving centraal staat, betekent gezondheid dat je het vermogen en de mogelijkheden hebt om je leven vorm te geven zoals je dat zelf waardevol vindt in het licht van de persoonlijke fysieke, emotionele en sociale uitdagingen. Vanuit dit nieuwe perspectief komt er binnen zorg en welzijn meer aandacht voor het verbeteren en het monitoren van het dagelijks functioneren van mensen en daarmee ook voor de omgevingsfactoren en persoonlijk factoren die op het functioneren van invloed zijn. Functioneren als focus van zorg en welzijn is geschreven voor iedereen werkzaam in zorg en welzijn – zoals de zorgprofessional, arboprofessional, beleidsmaker, ICT-specialist, sociaal en maatschappelijk werkende en onderzoeker - die het nieuwe gezondheidsperspectief wil implementeren in zijn/haar werk. Met de aanschaf van dit boek wordt tevens toegang verkregen tot de e-versie inclusief extra digitaal materiaal, zoals de uitwerking van opdrachten behorende bij de casuïstiek.
Functions: selection and mechanisms
by Philippe HunemanThis volume handles in various perspectives the concept of function and the nature of functional explanations, topics much discussed since two major and conflicting accounts have been raised by Larry Wright and Robert Cummins' papers in the 1970s. Here, both Wright's 'etiological theory of functions' and Cummins' 'systemic' conception of functions are refined and elaborated in the light of current scientific practice, with papers showing how the 'etiological' theory faces several objections and may in reply be revisited, while its counterpart became ever more sophisticated, as researchers discovered fresh applications for it. Relying on a firm knowledge of the original positions and debates, this volume presents cutting-edge research evincing the complexities that today pertain in function theory in various sciences. Alongside original papers from authors central to the controversy, work by emerging researchers taking novel perspectives will add to the potential avenues to be followed in the future. Not only does the book adopt no a priori assumptions about the scope of functional explanations, it also incorporates material from several very different scientific domains, e.g. neurosciences, ecology, or technology. In general, functions are implemented in mechanisms; and functional explanations in biology have often an essential relation with natural selection. These two basic claims set the stage for this book's coverage of investigations concerning both 'functional' explanations, and the 'metaphysics' of functions. It casts new light on these claims, by testing them through their confrontation with scientific developments in biology, psychology, and recent developments concerning the metaphysics of realization. Rather than debating a single theory of functions, this book presents the richness of philosophical issues raised by functional discourse throughout the various sciences.
The Functions, Disease-Related Dysfunctions, and Therapeutic Targeting of Neuronal Mitochondria
by Valentin K. Gribkoff J. Marie Hardwick Elizabeth A. JonasThis book presents advances in the field of neuronal mitochondria - functions, relation to therapeutics, and pharmacology. For scientists and researchers in both industry and academia, this book provides detailed discussion, examples, and approaches, to illustrate the potential of mitochondria as therapeutic targets for neuronal diseases. * Helps readers understand the regulation of mitochondrial cellular processes, such as substrate metabolism, energy production, and programmed versus sporadic cell death * Offers insights on the development of strategies for targeted therapeutic approaches and potential personalized treatments * Includes examples of mitochondrial drugs, development, and mitochondria-targeted approaches for more efficient treatment methods and further developments in the field * Covers the model systems and approaches needed for the development of new drugs for the central nervous system to provide potential modern therapeutics for neurodegenerative disorders
Functions: From Organisms to Artefacts (History, Philosophy and Theory of the Life Sciences #32)
by Jean Gayon Armand De Ricqlès Antoine C. DussaultThis book, originally published in French, examines the philosophical debates on functions over the last forty years and proposes new ways of analysis. Pervasive throughout the life sciences, the concept of function has the air of an epistemological scandal: ascribing a function to a biological structure or process amounts to suggesting that it is explained by its effects. This book confronts the debates on function with the use of the notion in a wide range of disciplines, such as biology, psychology, and medicine. It also raises the question of whether this notion, which is as old in the history of technology as it is in the life sciences, has the same meaning in these two domains.
Functions: selection and mechanisms (Synthese Library #363)
by Philippe HunemanThis volume handles in various perspectives the concept of function and the nature of functional explanations, topics much discussed since two major and conflicting accounts have been raised by Larry Wright and Robert Cummins’ papers in the 1970s. Here, both Wright’s ‘etiological theory of functions’ and Cummins’ ‘systemic’ conception of functions are refined and elaborated in the light of current scientific practice, with papers showing how the ‘etiological’ theory faces several objections and may in reply be revisited, while its counterpart became ever more sophisticated, as researchers discovered fresh applications for it. Relying on a firm knowledge of the original positions and debates, this volume presents cutting-edge research evincing the complexities that today pertain in function theory in various sciences. Alongside original papers from authors central to the controversy, work by emerging researchers taking novel perspectives will add to the potential avenues to be followed in the future. Not only does the book adopt no a priori assumptions about the scope of functional explanations, it also incorporates material from several very different scientific domains, e.g. neurosciences, ecology, or technology. In general, functions are implemented in mechanisms; and functional explanations in biology have often an essential relation with natural selection. These two basic claims set the stage for this book’s coverage of investigations concerning both ‘functional’ explanations, and the ‘metaphysics’ of functions. It casts new light on these claims, by testing them through their confrontation with scientific developments in biology, psychology, and recent developments concerning the metaphysics of realization. Rather than debating a single theory of functions, this book presents the richness of philosophical issues raised by functional discourse throughout the various sciences.
Fundamental and Advanced Fetal Imaging Ultrasound and MRI: Ultrasound And Mri
by Beth Kline-Fath Dorothy Bulas Wesley LeeWritten by leading fetal radiologists and maternal-fetal medicine specialists, with additional input from cardiologists, geneticists, and Doppler specialists, Fundamental and Advanced Fetal Imaging provides comprehensive, practical guidance on prenatal ultrasound and fetal MRI. This state-of-the-art 2nd Edition clearly presents the essential information you need on normal anatomy and techniques, screening of normal and abnormal conditions, and fetal malformations, helping you effectively evaluate obstetric patients and reach an accurate diagnosis for a wide variety of fetal anomalies.
Fundamental Biomechanics of Sport and Exercise
by James WatkinsFundamental Biomechanics of Sport and Exercise is an engaging and comprehensive introductory textbook that explains biomechanical concepts from first principles, showing clearly how the science relates to real sport and exercise situations. The book is divided into two parts. The first provides a clear and detailed introduction to the structure and function of the human musculoskeletal system and its structural adaptations, essential for a thorough understanding of human movement. The second part focuses on the biomechanics of movement, describing the forces that act on the human body and the effects of those forces on the movement of the body. Every chapter includes numerous applied examples from sport and exercise, helping the student to understand how mechanical concepts describe both simple and complex movements, from running and jumping to pole-vaulting or kicking a football. In addition, innovative worksheets for field and laboratory work are included that contain clear objectives, a description of method, data recording sheets, plus a set of exemplary data and worked analysis. Alongside these useful features are definitions of key terms plus review questions to aid student learning, with detailed solutions provided for all numerical questions. No other textbook offers such a clear, easy-to-understand introduction to the fundamentals of biomechanics. This is an essential textbook for any biomechanics course taken as part of degree programme in sport and exercise science, kinesiology, physical therapy, sports coaching or athletic training.
Fundamental Mathematics and Physics of Medical Imaging (Series in Medical Physics and Biomedical Engineering)
by Jack Lancaster Bruce HasegawaAuthored by a leading educator, this book teaches the fundamental mathematics and physics concepts associated with medical imaging systems. Going beyond mere description of imaging modalities, this book delves into the mechanisms of image formation and image quality common to all imaging systems: contrast mechanisms, noise, and spatial and temporal resolution, making it an important reference for medical physicists and biomedical engineering students. This is an extensively revised new edition of The Physics of Medical X-Ray Imaging by Bruce Hasegawa (Medical Physics Publishing, 1991), and includes a wide range of modalities such as X-ray CT, MRI and SPECT.
Fundamental Neuroscience, 4th Edition
by Larry Squire Darwin Berg Floyd E. Bloom Sascha Du Lac Anirvan Ghosh Nicholas C. SpitzerThe fourth edition of Fundamental Neuroscience reinvents itself as an engrossing and comprehensive presentation of the discipline of neuroscience, from molecules to cognition. Thorough but succinct, and lavishly illustrated, the book builds from an introductory section that includes fundamental neuroanatomy and goes on to cover cellular and molecular neuroscience, development, sensory systems, motor systems, regulatory systems, and behavioral and cognitive neuroscience. The book has been retooled to better serve its audience in the neuroscience and medical communities. The chapters include more than 100 boxes describing clinical conditions, techniques, and other special topics. Each chapter went through a thorough review process, giving the book an evenness of tone. The chapters are authored by outstanding working scientists who are experts on the topics they cover. Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries 30% new material including new chapters on dendritic development and spine morphogenesis, chemical senses, cerebellum, eye movements, circadian timing, sleep and dreaming, and consciousness Accompanying website for students and instructors Additional text boxes describing key experiments, disorders, methods, and concepts More than 650 four-color illustrations, micrographs, and neuroimages Multiple model system coverage beyond rats, mice, and monkeys Extensively expanded index for easier referencing
Fundamental Neuroscience, Second Edition
by Larry R. Squire James L. Roberts Nicholas C. Spitzer Michael J. Zigmond Susan K. Mcconnell Floyd E. BloomA definitive text in neuroscience.
Fundamental Nursing Skills and Concepts (Ninth Edition)
by Barbara Kuhn TimbyNow in its Ninth Edition, this text combines theoretical nursing concepts, step-by-step skills and procedures, and clinical applications to form the foundation of the LPN/LVN course of study. This edition features end-of-unit exercises, and extensively updated chapters on nursing foundations, laws and ethics, recording and reporting, nutrition, fluid and chemical balance, safety, asepsis, infection control, and medication administration. Coverage includes new information on cost-related issues, emerging healthcare settings, concept mapping, malpractice, documentation and reporting, HIPAA, and more. All Gerontologic Considerations sections have been thoroughly updated by renowned experts.
Fundamental Orthopedic Management for the Physical Therapist Assistant (Third Edition)
by Gary A. Shankman Robert C. ManskeDesigned to meet the unique needs of physical therapist assistants, Fundamental Orthopedic Management for the Physical Therapist Assistant, 3rd Edition focuses on critical thinking and helps you apply fundamental orthopedic principles in physical therapy interventions. Clear explanations cover basic concepts such as the PTA's role in physical assessment of flexibility, strength, endurance, and balance, along with the specifics of tissue healing; medications; gait and joint mobilization; and an introduction to biomechanics. It also describes the application of therapeutic interventions for many orthopedic conditions by region and affliction. Edited by two experienced clinicians, Gary A. Shankman and Robert C. Manske, and written by contributors who are experts in their respective fields, this is your one-stop source for PTA practice in orthopedics. Clear explanations of difficult concepts are provided by experienced, practicing clinicians who address the specific needs of the PTA. Comprehensive coverage provides a "one-stop" source for all things orthopedic, from core concepts related to orthopedics to information about the PTA's role in physical assessment and interventions, in-depth reviews of types of tissue healing, biomechanics, and pharmacology. A focus on critical thinking and application helps to prepare you for the treatment room and for the clinical practicum portions of the curriculum. Key terms and learning objectives begin each chapter, useful as "checkpoints" to which you can refer to ensure content comprehension and study effectively for examinations. Over 500 illustrations reinforce concepts and procedures, supplemented by summary tables and boxes. End-of-chapter review questions prepare you for the types of critical thinking you will be required to do in practice. Unique! End-of-chapter glossaries define key terms. Appendices provide a quick reference for information such as laboratory values, common medications, and associated movements. A six-part structure organizes the book's material: Part I: Basic Concepts of Orthopedic Management begins with the essential concepts of teamwork and shared responsibility within the physical therapy team and then covers the basic areas of flexibility, strength, endurance, balance, and coordination. Part II: Review of Tissue Healing introduces the types of tissue, then discusses ligament, bone, cartilage, muscle and tendon healing before looking briefly at neurovascular healing and thromboembolic disease. Part III: Common Medications in Orthopedics focuses on common medications used in orthopedics, their actions, side effects, and possible impact on treatment. Part IV: Mobilization and Biomechanics deals with the basics of human movement including a chapter on gait, and provides information on joint mobilization. Part V: Management of Orthopedic Conditions by Region covers the body from the ankle, foot, and toes up to the shoulder, the elbow, and the wrist and hand, including a chapter on the spine. NEW! Part VI: Management of Orthopedic Conditions by Affliction includes chapters on hot topics such as rheumatic disease; pain and pain-related syndromes; and bracing, orthotics, and prosthetics.
Fundamental Principles of Veterinary Anesthesia
by Gareth E. Zeiler Daniel S. J. PangFundamental Principles of Veterinary Anesthesia Comprehensive textbook integrating physiology and anesthesia of multiple species of animals in a unique practical setting Fundamental Principles of Veterinary Anesthesia is designed specifically for veterinary students, animal health technicians and veterinarians in general practice. The first edition of Fundamental Principles of Veterinary Anesthesia covers the key principles of veterinary anesthesia, encompassing a wide range of species, including dogs, cats, horses, cattle, and pigs, and establishing links between physiology, pharmacology, and clinical practice in healthy and ill patients. This text serves as a practical guide for students to prepare themselves for clinical work in a private practice setting, and as a rich, practical resource for those in general practice. This text is ideally used as a complete curriculum aligned resource, and the companion website is designed to decrease the burden of lecturers who need to compile PowerPoint presentations and review questions. Topics covered in Fundamental Principles of Veterinary Anesthesia include: Practical approaches to the peri-anesthetic period, from patient assessment, through to preparing for, and successfully completing, an anesthetic event Anesthetic drugs available in an academic or private practice, with a focus on commonly used drugs Components of the anesthetic machine, gas flow through the machine, how vaporizers work and their functionalities Principles and techniques of patient monitoring, with a focus on commonly available devices and their applications
Fundamental Skills for Mental Health Professionals
by Linda SeligmanThis book is intended to help students and novice clinicians, as well as more experienced clinicians, in the mental health professions of counseling, psychology, and social work to develop competence in the fundamental skills of their profession. With a solid grounding in such skills as effective use of questions, reflection of feelings, eliciting and modifying dysfunctional thoughts, and behavioral change strategies, clinicians can both acquire a sound understanding of their clients and develop strong helping skills.
Fundamental Statistical Methods for Analysis of Alzheimer's and Other Neurodegenerative Diseases
by Katherine E. Irimata Brittany N. Dugger Jeffrey R. WilsonA statistics textbook that delivers essential data analysis techniques for Alzheimer's and other neurodegenerative diseases.Alzheimer's disease is a devastating condition that presents overwhelming challenges to patients and caregivers. In the face of this relentless and as-yet incurable disease, mastery of statistical analysis is paramount for anyone who must assess complex data that could improve treatment options. This unique book presents up-to-date statistical techniques commonly used in the analysis of data on Alzheimer's and other neurodegenerative diseases. With examples drawn from the real world that will make it accessible to disease researchers, practitioners, academics, and students alike, this volume• presents code for analyzing dementia data in statistical programs, including SAS, R, SPSS, and Stata• introduces statistical models for a range of data types, including continuous, categorical, and binary responses, as well as correlated data• draws on datasets from the National Alzheimer's Coordinating Center, a large relational database of standardized clinical and neuropathological research data• discusses advanced statistical methods, including hierarchical models, survival analysis, and multiple-membership• examines big data analytics and machine learning methodsEasy to understand but sophisticated in its approach, Fundamental Statistical Methods for Analysis of Alzheimer's and Other Neurodegenerative Diseases will be a cornerstone for anyone looking for simplicity in understanding basic and advanced statistical data analysis topics. Allowing more people to aid in analyzing data—while promoting constructive dialogues with statisticians—this book will hopefully play an important part in unlocking the secrets of these confounding diseases.