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Generation Roe: Inside the Future of the Pro-Choice Movement
by Sarah ErdreichStrong support among women was key to Obama's reelection. At the start of his second term, it is time for Barack Obama, forty years after Roe v. Wade, to finally help lead us to demystify abortion. One-third of all American women will have an abortion by the time they are 45, and most of those women are already mothers. Yet, the topic remains taboo. In this provocative book on the heels of the Planned Parenthood controversy, Sarah Erdreich presents the antidote to the usual abortion debates. Inextricably connected to issues of autonomy, privacy, and sexuality, the abortion debate remains home base for the culture wars in America. Yet, there is more common ground than meets the eye in favor of choice. Generation Roe delves into phenomena such as "abortion-recovery counseling," "crisis pregnancy centers," and the infamous anti-choice "black children are an endangered species" billboards. It tells the stories of those who risk their lives to pursue careers in this stigmatized field. And it outlines the outrageous legislative battles that are being waged against abortion rights all over the country. With an inspiring spirit and a forward-looking approach, Erdreich holds abortion up, unabashedly, as a moral and fundamental human right.
Generation Rx: How Prescription Drugs Are Altering American Lives, Minds, and Bodies
by Greg CritserThis in-depth look at the rise of Big Pharma and pill marketing is &“a page-turner&” (Booklist, starred review). A finalist for a PEN America Literary Award for Research Nonfiction, this book takes a deep look at how the pharmaceutical industry—with some help from the medical and insurance fields and from American consumers themselves—has pushed its products, often at the expense of our health. Generation Rx reveals the roots of many of the widespread societal problems we face today, explaining how marketing efforts changed powerful chemical compounds for chronic diseases, once controlled by physicians, into substances we feel entitled to, whether we need them or not. Using exclusive interviews with the strategists, scientists, and current and former heads of GlaxoSmithKline, Eli Lilly, Merck, Roche, and more, the author of Fat Land presents a &“fascinating and disturbing&” story of business interests unleashed on an unsuspecting public, and a cultural shift that has caused lasting—and sometimes lethal—damage (New Scientist). &“What Fast Food Nation did for the way Americans eat, Greg Critser does for the way we medicate ourselves.&” —Michael Pollan, bestselling author of The Omnivore&’s Dilemma
Generational Intelligence: A Critical Approach to Age Relations
by Simon Biggs Ariela LowensteinThe question of communication and understanding between different generations is emerging as a key issue for the twenty-first century. The advent of ageing populations may lead to increased conflict or solidarity in society, and provokes a profound ambivalence both in public and in the private sphere. In a new approach, Biggs and Lowenstein offer a critical examination of Generational Intelligence as one way of addressing these issues. How easy is it to put yourself in the shoes of someone of a different age group? What are the personal, interpersonal and social factors that affect our perceptions of the ‘age other’? What are the key issues facing families, workplaces and communities in an ageing society? This book sets out a way of thinking about interpersonal relations based on age, and the question of communication between people of different ages and generations. The book challenges existing orthodoxies for relations between adults of different ages and draws out steps that can be taken to increase understanding between generational groups. The authors outline a series of steps that can be taken to enhance Generational Intelligence, examine existing theories and social issues, and suggest new directions for sustainable relations between generational groups.
Generationenmanagement in Arzt- und Zahnarztpraxis: Von Jung bis Alt ein starkes Team
by Isabell Lütkehaus Stephan F. KockNicht nur der demografische Wandel führt zu einer anderen Arbeits- und Praxiswelt, sondern auch die unterschiedlichen Wünsche, Erwartungen, Werte und Befürchtungen der unterschiedlichen Mitarbeitergenerationen - von der Generation Y bis zu den Babyboomern - in Arzt- und Zahnarztpraxen. Diesem Wandel und Wettbewerb um die besten Köpfe sind Praxisinhaber und -inhaberinnen aber auch Leitungskräfte in medizinischen Versorgungszentren ausgesetzt. Wo gestern noch aus dem Vollen geschöpft werden konnte, regiert heute der Fachkräftemangel, den es sowohl mitarbeiter- als auch teamorientiert zu managen gilt. Ziel dieses Ratgebers ist es, einen Beitrag zur Verbesserung des generationenübergreifenden Miteinanders in Arzt-, Zahnarztpraxen und Medizinischen Versorgungszentren zu leisten. Die Autoren beschreiben anhand eines durchgängigen Beispiels, welche Schwierigkeiten es in der Praxis zu bewältigen gilt und wie ein gutes und professionelles Miteinander gelingen kann, bei dem auf die unterschiedlichen Mitarbeiterbedürfnisse eingegangen wird. Hilfreiche Checklisten und Tipps für den Praxisalltag runden das Buch ab. So finden Praxisinhaber und –inhaberinnen Sicherheit für ihr tägliches Tun, gewinnen Zeit für das Wesentliche und werden „nebenbei“ zu attraktiven Arbeitgebern, denen in der Gesundheitsbranche die Zukunft gehört.
Generationenübergreifende Analyse von Straftätern und die Rolle der emotionalen Intelligenz im Strafjustizsystem (essentials)
by Otilia Gudana Sabrina StamborskiIm Jahr 1996 wurde Gewalt weltweit zum Gesundheitsproblem erklärt und identifiziert. Das Risiko von Mord und Selbstmord erreichte epidemische Ausmaße und betraf bestimmte Bevölkerungsgruppen, darunter Jugendliche und Angehörige von Minderheitengruppen. Die Selbstmordraten bei Jugendlichen und jungen Erwachsenen (15 bis 24 Jahre) haben sich zwischen 1950 und 1990 fast verdreifacht. Ebenso haben sich die Mordraten bei 15- bis 19-jährigen Männern von 1985 bis 1991 fast verdoppelt. Diese Trends löste weltweit Alarm aus und verlangten nach neuen Lösungen.Die Motivation dieses Buches bestand darin, das Niveau der emotionalen Intelligenz von Kriminellen in Gefängnissen und in forensischen psychiatrischen Einrichtungen zu vergleichen. Das Hauptziel dieser Analyse besteht darin, sich auf Empfehlungen zum Training emotionaler Intelligenz zu konzentrieren, um die epidemische Gewaltraten von Insassen auf globaler Ebene zu senken.
Generic: The Unbranding of Modern Medicine
by Jeremy A. GreeneThe turbulent history of generic pharmaceuticals raises powerful questions about similarity and difference in modern medicine.Generic drugs are now familiar objects in clinics, drugstores, and households around the world. We like to think of these tablets, capsules, patches, and ointments as interchangeable with their brand-name counterparts: why pay more for the same? And yet they are not quite the same. They differ in price, in place of origin, in color, shape, and size, in the dyes, binders, fillers, and coatings used, and in a host of other ways. Claims of generic equivalence, as physician-historian Jeremy Greene reveals in this gripping narrative, are never based on being identical to the original drug in all respects, but in being the same in all ways that matter.How do we know what parts of a pill really matter? Decisions about which differences are significant and which are trivial in the world of therapeutics are not resolved by simple chemical or biological assays alone. As Greene reveals in this fascinating account, questions of therapeutic similarity and difference are also always questions of pharmacology and physiology, of economics and politics, of morality and belief.Generic is the first book to chronicle the social, political, and cultural history of generic drugs in America. It narrates the evolution of the generic drug industry from a set of mid-twentieth-century "schlock houses" and "counterfeiters" into an agile and surprisingly powerful set of multinational corporations in the early twenty-first century.The substitution of bioequivalent generic drugs for more expensive brand-name products is a rare success story in a field of failed attempts to deliver equivalent value in health care for a lower price. Greene’s history sheds light on the controversies shadowing the success of generics: problems with the generalizability of medical knowledge, the fragile role of science in public policy, and the increasing role of industry, marketing, and consumer logics in late-twentieth-century and early twenty-first century health care.
Generic Challenge: Understanding Patents, FDA and Pharmaceutical Life-Cycle Management (Fifth Edition)
by Martin a. VoetThis Fifth Edition of The Generic Challenge provides important new updates on current regulatory, legal and commercial issues affecting brand and generic pharmaceutical products, including new laws establishing generics for biologics, and changes brought about by the recently enacted America Invents Act. It explains clearly and understandably the roles of patents, FDA regulation of drugs and the Hatch Waxman Act in commercial drug development in light of generic challenges and how improvements in innovative drug products provide benefits to patients while extending the commercial lives of the drugs. There is simply no other book of its kind on this important subject.
The Generic Challenge: Understanding Patents, FDA and Pharmaceutical Life-Cycle Management (Sixth Edition)
by Martin A VoetThis Sixth Edition of The Generic Challenge provides important new updates on current regulatory, legal and commercial issues affecting brand and generic pharmaceutical products, including new laws establishing generics for biologics, and changes brought
Generics and Bioequivalence (Routledge Revivals)
by Andre J. JacksonPublished in 1994: This text focuses on the determination of bioequivalence between formulations that are pharmaceutically equivalent and manufactured using acceptable chemistry, manufacturing and controls and in accordance with Good Manufacturing Practices.
The Generosity of the Dead: A Sociology of Organ Procurement in France (Medical Law and Ethics)
by Graciela NowensteinThere has been a general assumption in the international debate surrounding organ procurement that Presumed Consent (opting-out) systems produce better results than Express Consent (opting-in) systems. This study uses the French case to challenge this widely held assumption and argues that the French presumed consent systems coexist with patterns of behaviour that in practice do not mobilize the law. It explores four key areas to current research in socio-legal studies focussing on the state and nature of social solidarity, social engineering and the changing nature of the citizen-state relations, state intervention in the event of death and discretion in use of corpses and recent modifications of the status of medical professionals as figures of authority and agents of state policy. Using material based on interviews with medical professionals, this title will be a valuable resource for researchers, academics, policy-makers and practitioners with an interest in this complex and topical subject.
Genes and Cardiovascular Function
by Naranjan S. Dhalla Makoto Nagano Bohuslav OstadalRapid advances in molecular medicine have led to pronounced new developments in experimental and clinical cardiology. In the embrace of modern molecular biology and bridging the gap between the clinical and the genomic, cardiovascular medicine has seen major strides in the understanding of the molecular mechanisms that drive disease progression. The ability to rapidly identify candidate human genes for cardiovascular diseases lends itself to the development of diverse strategies for disease treatment and management. The wide variety of gene expressions proffers excellent targets for novel therapeutics. Gene therapy is steadily increasing in viability and represents a fascinating arena of research and clinical focus. This book is based on two international Mendel symposia on "Genes and the Heart," joint meetings of the Japanese and European sections of the International Academy of Cardiovascular Sciences. Highlighting selected symposia contributions, this book explores the role of molecular biology and genetics in the basic knowledge, genesis, and clinical interventions of cardiovascular diseases.
Genes and Signal Transduction in Multistage Carcinogenesis
by Nancy H. ColburnThis book describes the identification and characterization of genetic loci that determine susceptibility to liver, mammary, or skin carcinogenesis in rodents. It focuses on protein kinases and phospholipases, and stress-related signal transduction.
Genes, Brains, and Human Potential: The Science and Ideology of Intelligence
by Ken RichardsonFor countless generations people have been told that their potential as humans is limited and fundamentally unequal. The social order, they have been assured, is arranged by powers beyond their control. More recently the appeal has been to biology, specifically the genes, brain sciences, the concept of intelligence, and powerful new technologies. Reinforced through the authority of science and a growing belief in bio-determinism, the ordering of the many for the benefit of a few has become more entrenched. Yet scientists are now waking up to the influence of ideology on research and its interpretation. In Genes, Brains, and Human Potential, Ken Richardson illustrates how the ideology of human intelligence has infiltrated genetics, brain sciences, and psychology, flourishing in the vagueness of basic concepts, a shallow nature-versus-nurture debate, and the overhyped claims of reductionists. He shows how ideology, more than pure science, has come to dominate our institutions, especially education, encouraging fatalism about the development of human intelligence among individuals and societies. Genes, Brains, and Human Potential goes much further: building on work being done in molecular biology, epigenetics, dynamical systems, evolution theory, and complexity theory, it maps a fresh understanding of intelligence and the development of human potential. Concluding with an upbeat message for human possibilities, this synthesis of diverse perspectives will engender new conversations among students, researchers, and other interested readers.
Genes, Memes, Culture, and Mental Illness
by Hoyle LeighWhat produces mental illness: genes, environment, both,neither? The answer can be found in memes--replicable units of information linking genes and environment in the memory and in culture--whose effects on individual brain development can be benign or toxic. This book reconceptualizes mental disorders as products of stressful gene-meme interactions and introduces a biopsychosocial template for meme-based diagnosis and treatment. A range of therapeutic modalities, both broad-spectrum (meditation) and specific(cognitive-behavioral), for countering negative memes and their replication are considered, as are possibilities for memetic prevention strategies. In this book, the author outlines the roles of genes and memes in the evolution of the human brain; elucidates the creation, storage, and evolution of memes within individual brains; examines culture as a carrier and supplier of memes to the individual; provides examples of gene-meme interactions that can result in anxiety, depression, and other disorders; proposes a multiaxial gene-meme model for diagnosing mental illness; identifies areas of meme-based prevention for at-risk children; and defines specific syndromes in terms of memetic symptoms, genetic/ memetic development, and meme-based treatment.
Genesis
by Robin CookNew York Times-bestselling author Robin Cook takes on the ripped-from-the-headlines topic of harnessing DNA from ancestry websites to catch a killer in this timely and explosive new medical thriller.When the body of twenty-eight-year-old social worker Kera Jacobsen shows up on Chief New York City Medical Examiner Laurie Montgomery's autopsy table, at first it appears she was the victim of a tragic yet routine drug overdose. But for Laurie and her new pathology resident, the brilliant but enigmatic Dr. Aria Nichols, little things aren't adding up. Kera's family and friends swear she never touched drugs. Administrators from the hospital where Kera worked are insisting the case be shrouded in silence. And although Kera was ten weeks pregnant, nobody seems to know who the father was--or whether he holds the key to Kera's final moments alive.As a medical emergency temporarily sidelines Laurie, impulsive Aria turns to a controversial new technique: using genealogic DNA databases to track down those who don't want to be found. Working with experts at a start-up ancestry website, she plans to trace the fetus's DNA back to likely male relatives in the hopes of identifying the mystery father. But when Kera's closest friend and fellow social worker is murdered, the need for answers becomes even more urgent. Because someone out there clearly doesn't want Kera's secrets to come to light . . . and if Aria gets any closer to the truth, she and Laurie might find themselves a killer's next targets.
The Genesis Machine: Our Quest to Rewrite Life in the Age of Synthetic Biology
by Amy Webb Andrew HesselNamed one of The New Yorker's BEST BOOKS OF 2022 SO FARThe next frontier in technology is inside our own bodies. Synthetic biology will revolutionize how we define family, how we identify disease and treat aging, where we make our homes, and how we nourish ourselves. This fast-growing field—which uses computers to modify or rewrite genetic code—has created revolutionary, groundbreaking solutions such as the mRNA COVID vaccines, IVF, and lab-grown hamburger that tastes like the real thing. It gives us options to deal with existential threats: climate change, food insecurity, and access to fuel. But there are significant risks. Who should decide how to engineer living organisms? Whether engineered organisms should be planted, farmed, and released into the wild? Should there be limits to human enhancements? What cyber-biological risks are looming? Could a future biological war, using engineered organisms, cause a mass extinction event? Amy Webb and Andrew Hessel&’s riveting examination of synthetic biology and the bioeconomy provide the background for thinking through the upcoming risks and moral dilemmas posed by redesigning life, as well as the vast opportunities waiting for us on the horizon.
The Genesis of Technoscientific Revolutions: Rethinking the Nature and Nurture of Research
by Venkatesh Narayanamurti Jeffrey Y. TsaoResearch powers innovation and technoscientific advance, but it is due for a rethink, one consistent with its deeply holistic nature, requiring deeply human nurturing. Research is a deeply human endeavor that must be nurtured to achieve its full potential. As with tending a garden, care must be taken to organize, plant, feed, and weed—and the manner in which this nurturing is done must be consistent with the nature of what is being nurtured. In The Genesis of Technoscientific Revolutions, Venkatesh Narayanamurti and Jeffrey Tsao propose a new and holistic system, a rethinking of the nature and nurturing of research. They share lessons from their vast research experience in the physical sciences and engineering, as well as from perspectives drawn from the history and philosophy of science and technology, research policy and management, and the evolutionary biological, complexity, physical, and economic sciences. Narayanamurti and Tsao argue that research is a recursive, reciprocal process at many levels: between science and technology; between questions and answer finding; and between the consolidation and challenging of conventional wisdom. These fundamental aspects of the nature of research should be reflected in how it is nurtured. To that end, Narayanamurti and Tsao propose aligning organization, funding, and governance with research; embracing a culture of holistic technoscientific exploration; and instructing people with care and accountability.
The Genetic Age: Our Perilous Quest To Edit Life
by Matthew Cobb'Brilliant .. I cannot recommend this book strongly enough' - Henry Marsh, New Statesman (about The Idea of the Brain)A new gene editing technology, invented just seven years ago, has turned humanity into gods. Enabling us to manipulate the genes in virtually any organism with exquisite precision, CRISPR has given scientists a degree of control that was undreamt of even in science fiction.But CRISPR is just the latest, giant leap in a long journey to master genetics. The Genetic Age shows the astonishing, world-changing potential of the new genetics and the possible threats it poses, sifting between fantasy and the reality when it comes to both benefits and dangers.By placing each phase of discovery, anticipation and fear in the context of over fifty years of attempts to master the natural world, Matthew Cobb, the Baillie-Gifford-shortlisted author of The Idea of the Brain, weaves the stories of science, history and culture to shed new light on our future. With the powers now at our disposal, it is afuture that is almost impossible to imagine - but it is one we will create ourselves.
Genetic and Molecular Epidemiology of Multiple Myeloma
by Suzanne LentzschMultiple myeloma is a plasma cell malignancy characterized by complex heterogenous cytogenetic abnormalities that accounts for 1.4% of all cancers, and approximately 10% of hematologic malignancies. The clinical manifestations of multiple myeloma include lytic bone lesions, cytopenia, hypercalcemia, renal dysfunction, hyperviscosity of the blood, immunodeficiency, and peripheral neuropathy. Based on the clinical and genetic data, probably all cases of multiple myeloma arise from an asymptomatic monoclonal gammopathy of unknown significance. The exact mechanism of the transition from MGUS to overt multiple myeloma is still not well understood. Recent oncogenomic studies have further advanced our understanding of the molecular pathogenesis of multiple myeloma. This book will give a comprehensive overview of the genetic and molecular epidemiology of multiple myeloma in order to get a more refined and conclusive understanding of this disease.
Genetic Association Studies: Background, Conduct, Analysis, Interpretation
by Mehmet Tevfik DorakGenetic Association Studies is designed for students of public health, epidemiology, and the health sciecnes, covering the main principles of molecular genetics, population genetics, medical genetics, epidemiology and statistics. It presents a balanced view of genetic associations with coverage of candidate gene studies as well as genome-wide association studies. All aspects of a genetic association study are included, from the lab to analysis and interpretation of results, but also bioinformatics approaches to causality assessment. The role of the environment in genetic disease is also highlighted. Genetic Association Studies will enable readers to understand and critique genetic association studies and set them on the way to designing, executing, analyzing, interpreting, and reporting their own.
Genetic Basis of Oral Health Conditions
by Alexandre Rezende VieiraThis book explains the genetic basis of a wide range of dental disorders, including dental caries, periodontitis, congenital anomalies, malocclusions, orofacial pain, dental implant failure, and cancer. Such conditions are typically multifactorial or complex, with involvement of more than one gene as well as environmental influences. A sound grasp of this framework is ever more important, given the emergence of consumer genomics, including direct-to-consumer genetic testing. Dental professionals now need to understand why one person is susceptible to a particular oral health condition while a first-degree relative either does not develop the condition or does so in a less severe form. Knowledge of how genes operate in the susceptible host is essential if patients are to be offered accurate advice about their risks. The information provided in this book will assist in the delivery of effective personalized dental care through optimization of preventive strategies. It will enable the practitioner to explain the extent to which a patient’s condition is pure "bad luck", whether that bad luck can be changed by behavioral choices, and how many of our behaviors are influenced by genes.
Genetic Cardiomyopathies
by Fulvio Camerini Gianfranco Sinagra Luisa MestroniIn the last decade, genetics has been emerging as a primary issue in the diagnosis and management of cardiomyopathies. This book is intended to be a state-of-the-art monograph on these diseases, describing their genetic causes, defining the molecular basis and presenting extensive descriptions of genotype-phenotype correlations. Other chapters are focused on the role of clinical observation, on ECG and echocardiography. With its highlight on the most recent discoveries in the field of molecular genetics as well as on the correct clinical approach to patients with heart muscle disease, the book is aimed at physicians and clinical cardiologists with a particular interest in myocardial diseases and in their genetic causes.
Genetic Causes of Cardiac Disease (Cardiac and Vascular Biology #7)
by Jeanette Erdmann Alessandra MorettiThis book provides a comprehensive summary of the latest developments in the field of the genomics of cardiac disease. Written and edited by leading clinicians and scientists involved in the analysis and therapy of genetic cardiac disorders, it discusses the genetic causes of a variety of cardiac diseases, such as the complex genetics and etiology of congenital heart diseases. It also explores sex differences in prevalent diseases, genetics-based therapeutic strategies and the use of various animal models and alternatives. The book is intended for research scientists and clinical scientists in the cardiovascular field, human geneticists and cardiologists.
Genetic Counseling: Ethical Challenges and Consequences
by Dianne M. Bartels Bonnie S. LeRoy Arthur L. CaplanGenetic counseling is fairly new. The fact that the field is an accepted professional enterprise in universities, clinics, and hospitals throughout the United States is remarkable. The contributors argue that genetics and medicine rest on beliefs widely held in American society. Scientific progress is good, and highly sophisticated technologies are appropriate means to solving medical problems. The better understanding they gain about the nature and evolution of disease, the more prepared clinicians will be to treat and prevent future occurrence of disease. A belief that medicine, including genetic medicine, is clear, factually based, and objective undergirds the strategies and norms of genetic counseling. This collection of original papers explores the history, values, and norms of that process, with focus on the value of non-directiveness in counseling practice. The contributors' examination of genetic counseling issues serves as a foundation from which to address the ethical, legal, and policy considerations of clinical genetics.
Genetic Counseling and Preventive Medicine in Post-War Bosnia
by Philip C. AkaGenetic Counseling and Preventive Medicine in Post-War Bosnia offers a unique new perspective to longstanding debates on healthcare reforms in Bosnia. In this penetrating analysis, Philip C. Aka argues that twenty-five years after the ethnic war that shook Bosnia and Herzegovina to its foundations, healthcare reforms are a function of preventive medicine, defined as genetic counselling, backed by tobacco and alcohol control. At its core, the book offers a fresh examination of healthcare reforms in Bosnia set in the multidisciplinary field of bioethics, supplemented by comparative health studies, and comparative human rights. By offering an extensive list of electronically accessible literature on healthcare accessible in the public domain, Aka delivers an exemplar of research possibilities in the Information Age.