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If I Should Lose You

by Natasha Lester

Camille is a nurse specializing in supporting families through the difficult decision to donate the organs of their dying loved ones. Camille's mother is a gifted but uncompromising transplant surgeon determined to make it in a man's world until her own life falls apart. And Camille herself is a mother to Addie - five years old, critically ill and in desperate need of the very organs her mother and grandmother work with.

If I Should Lose You

by Natasha Lester

Camille works as an organ transplant nurse, counselling families through heart-rending decisions. But at home, her own daughter Addie is critically ill. When an invitation to curate an exhibit arrives from artist Jack Darcy, her late mother' s lover, Camille is plunged into unresolved questions about her childhoood and her mother' s life.As Addie gets sicker, Camille wonders how far she will go to save her child – and how much of herself she can give when she has everything to lose.

If I'm So Strong, Why Do I Feel So Weak?: Helping Those Who Help Others Help Themselves

by Eleanor Miller

If I’m So Strong, Why Do I Feel So Weak teaches rescue workers and others who have chosen self-sacrificing work how to help themselves while still helping others. There are so many who choose a self-sacrificing field of work, such as those who work in Emergency Medical Services, who feel self-doubt when it comes to taking care of themselves. They spend so much time saving the rest of the world that it no longer feels good for them. Eleanor Miller lived that life. And after years of searching, she understands why the popular remedies just don’t cut it. She offers guidance to readers on how to say no without feeling guilty, how to find their own voice, strength, and confidence and so much more on their path to recognizing their own importance.

If It Sounds Like a Quack...: A Journey to the Fringes of American Medicine

by Matthew Hongoltz-Hetling

A Pulitzer Prize finalist's bizarre journalistic journey through the world of fringe medicine, filled with leeches, baking soda IVs, and, according to at least one person, zombies. It's no secret that American health care has become too costly and politicized to help everyone. So where do you turn if you can't afford doctors, or don't trust them? In this book, Matthew Hongoltz-Hetling examines the growing universe of non-traditional treatments -- including some that are really non-traditional. With costs skyrocketing and anti-science sentiment spreading, the so-called "medical freedom" movement has grown. Now it faces its greatest challenge: going mainstream. In these pages you'll meet medical freedom advocates including an international leech smuggler, a gold miner-turned health drink salesman who may or may not be from the Andromeda galaxy, and a man who says he can turn people into zombies with aerosol spray. One by one, these alternative healers find customers, then expand and influence, always seeking the one thing that would take their businesses to the next level--the support and approval of the government. Should the government dictate what is medicine and what isn't? Can we have public health when disagreements over science are this profound? No, seriously, can you turn people into flesh-eating zombies? If It Sounds Like a Quack asks these critical questions while telling the story of how we got to this improbable moment, and wondering where we go from here. Buckle up for a bumpy ride...unless you're against seatbelts.

If Only They Could Talk

by James Herriot

Animal stories from a vet's perspective.

If That Ever Happens to Me: Making Life and Death Decisions after Terri Schiavo

by Lois Shepherd

Every day, thousands of people quietly face decisions as agonizing as those made famous in the Terri Schiavo case. Throughout that controversy, all kinds of people--politicians, religious leaders, legal and medical experts--made emphatic statements about the facts and offered even more certain opinions about what should be done. To many, courts were either ordering Terri's death by starvation or vindicating her constitutional rights. Both sides called for simple answers. If That Ever Happens to Medetails why these simple answers were not right for Terri Schiavo and why they are not right for end-of-life decisions today. Lois Shepherd looks behind labels like "starvation," "care," or "medical treatment" to consider what care and feeding really mean, when feeding tubes might be removed, and why disability groups, the faithful, and even the dying themselves often suggest end-of-life solutions that they might later regret. For example, Shepherd cautions against living wills as a pat answer. She provides evidence that demanding letter-perfect documents can actually weaken, rather than bolster, patient choice. The actions taken and decisions made during Terri Schiavo's final years will continue to have repercussions for thousands of others--those nearing death, their families, health-care professionals, attorneys, lawmakers, clergy, media, researchers, and ethicists. If That Ever Happens to Meis an excellent choice for anyone interested in end-of-life law, policy, and ethics--particularly readers seeking a deeper understanding of the issues raised by Terri Schiavo's case.

If This Is A Man/The Truce: And, The Truce

by Primo Levi

With the moral stamina and intellectual pose of a twentieth-century Titan, this slightly built, duitful, unassuming chemist set out systematically to remember the German hell on earth, steadfastly to think it through, and then to render it comprehensible in lucid, unpretentious prose. He was profoundly in touch with the minutest workings of the most endearing human events and with the most contempible. What has survived in Levi's writing isn't just his memory of the unbearable, but also, in THE PERIODIC TABLE and THE WRENCH, his delight in what made the world exquisite to him. He was himself a "magically endearing man, the most delicately forceful enchanter I've ever known" - PHILIP ROTH

If This Is A Man/The Truce

by Primo Levi

"With the moral stamina and intellectual poise of a twentieth-century Titan, this slightly built, dutiful, unassuming chemist set out systematically to remember the German hell on earth, steadfastly to think it through, and then to render it comprehensible in lucid, unpretentious prose. He was profoundly in touch with the minutest workings of the most endearing human events and with the most contemptible. What has survived in Levi's writing isn't just his memory of the unbearable, but also, in THE PERIODIC TABLE and THE WRENCH, his delight in what made the world exquisite to him. He was himself a magically endearing man, the most delicately forceful enchanter I've ever known" - PHILIP ROTH

If You Are There: A Novel

by Susan Sherman

Set in the early 1900s, the novel follows young Lucia Rutkowski who, thanks to the influence of her beloved grandmother, escapes the Warsaw ghetto to work as a kitchen maid in one of the wealthiest neighborhoods in the bustling city of Paris. Too talented for her lowly position, Lucia is thrown out on the street. Her only recourse is to take a job working for two disorganized, rather poor married scientists so distracted by their work that their house and young child are often neglected. Lucia soon bonds with her eccentric employers, watching as their work with radioactive materials grows increasing noticed by the world, then rising to fame as the great Marie and Pierre Curie. Soon, all of Paris is alit with the news of an impending visit from Eusapia Palladino, the worlds most famous medium. It is through her now famous employers that Lucia attends Eusapias gatherings and eventually falls under the mediums spell, leaving the Curie household to travel with her to Italy. Ultimately, Lucia is placed directly in the crosshairs of faith versus science –what is more real, the glowing substances of the Curie laboratory or the glowing visions that surround the medium during her seance?

If Your Mouth Could Talk: An In-Depth Guide to Oral Health and Its Impact on Your Entire Life

by Kami Hoss

You&’ve heard the advice: If you want to live longer, eat healthy foods and exercise daily. But there&’s a third piece of the puzzle, and it can add 10 to 15 years to your life.It&’s been right under your nose this whole time—literally.Your mouth is the gateway to your body and is the most critical organ for improving your health, from childhood onward. Everything in the human life cycle is related to the mouth: fertility, childbirth, sleeping soundly, success in school, finding a mate, getting a job, psychological well-being, avoiding chronic or systemic disease, and aging well. Your mouth is a window into the health of your body as a whole; from its microbiome to its structure, it impacts your physical and mental wellness in countless ways. Unfortunately, the mouth-body connection has been largely neglected by American medicine . . . until now. If Your Mouth Could Talk is the result of over 20 years of firsthand experience and research by renowned orthodontist and dentofacial orthopedist, Dr. Kami Hoss. In this groundbreaking work, Dr. Hoss connects the dots between oral health and whole-body health, offering a roadmap to a longer, more successful future for you and your family. This isn&’t a book about brushing and flossing—or any of the other standard advice you get from your dentist. Instead, you&’ll hear about how to protect your mouth&’s microbiome, the effect of diet, the relationship between oral structure and sleep problems, how to breathe better, and more. This is an in-depth guide for people who want to take control of their health to the fullest extent possible—who want to understand how their mouth contributes to their overall health and quality of life, and what they can do to better care for it. If your mouth could talk, it would tell you about the condition of your entire life. Time to start listening.

IFLScience 117 Things You Should F*#king Know About Your World

by Paul Parsons The Writers of IFLScience

IFLScience presents the most intriguing and far-out facts about space, technology, the human brain, nature, and so much more that you should know, right now!117 Things You Should F*#ing Know About Your World is a compendium of the greatest articles from IFLScience's long history, broken up by leading subjects: Health & Medicine Plants & Animals Technology The Brain Space The Environment Chemistry PhysicsEach chapter opens with a new and irreverent introduction to the subject and collection of stories by author Paul Parsons, and the book features fascinating sidebars on related stories, photos, and illustrations throughout.From pinpointing the exact worst time to be alive in human history, to learning what makes you a procrastinator or a go-getter, to the very key to a happy sex life, and so much more, this is the science book that only the world's leading source of crazy-but-true stories could produce.

IgE Antibodies: Generation and Function

by Juan J. Lafaille Maria A. Curotto de Lafaille

This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.

Igelino hat Hummeln im Bauch: Aufmerksamkeitsstörungen kindgerecht erklärt

by Lisa Pongratz

Jedes Buch der Serie vom kleinen Igel Igelino thematisiert eine häufig vorkommende psychische Erkrankung im Kindes- und Jugendalter. Die Geschichten und Erklärungen sind auf kindgerechte, enttabuisierende Weise gestaltet und von einem jungen, künstlerischen Talent illustriert.Mit diesem Ratgeber erhalten Eltern und Angehörige die Möglichkeit, ihren noch jungen Kindern mit Hilfe der Geschichte von Igelino die menschliche Psyche im Falle einer Aufmerksamkeitsdefizitstörung (ADHS) altersgerecht verständlich zu machen. Hierbei liegt der Fokus jedoch nicht auf der eigenen Erkrankung bzw. den eigenen Symptomen, sondern auch in der Vermittlung von Wissen über psychische Störungen bei Familienmitgliedern, Freund*innen oder Klassenkamerad*innen mit Verhaltensauffälligkeiten.Eltern erhalten darüber hinaus wichtige grundlegende Informationen zur psychischen Störung, Tipps, wie eine solche Störung erkannt (und von anderen Verhaltensauffälligkeiten abgegrenzt) werden kann, wie man sich gegenüber Betroffenen verhält, sowie Informationen über Therapiemöglichkeiten, Anlaufstellen für Hilfsangebote und eigenständig durchführbare Interventionen in Form von Ressourcenübungen.

Igelino kann nicht anders: Zwangsstörungen kindgerecht erklärt

by Lisa Pongratz

Jedes Buch der Serie vom kleinen Igel Igelino thematisiert eine häufig vorkommende psychische Erkrankung im Kindes- und Jugendalter. Die Geschichten und Erklärungen sind auf kindgerechte, enttabuisierende Weise gestaltet und von einem jungen, künstlerischen Talent illustriert.Mit diesem Ratgeber erhalten Eltern und Angehörige die Möglichkeit, ihren noch jungen Kindern mit Hilfe der Geschichte von Igelino die menschliche Psyche im Falle einer Zwangsstörung altersgerecht verständlich zu machen. Hierbei liegt der Fokus jedoch nicht auf der eigenen Erkrankung bzw. den eigenen Symptomen, sondern auch in der Vermittlung von Wissen über psychische Störungen bei Familienmitgliedern, Freund*innen oder Klassenkamerad*innen mit Verhaltensauffälligkeiten.Eltern erhalten darüber hinaus wichtige grundlegende Informationen zur psychischen Störung, Tipps, wie eine solche Störung erkannt (und von anderen Verhaltensauffälligkeiten abgegrenzt) werden kann, wie man sich gegenüber Betroffenen verhält, sowie Informationen über Therapiemöglichkeiten, Anlaufstellen für Hilfsangebote und eigenständig durchführbare Interventionen in Form von Ressourcenübungen.1. Psychische Störungen: Zahlen und Fakten.- 2. Tipps zum gemeinsamen Lesen. -3. Igelino kann nicht anders.- 4. Was ist eine Zwangsstörung?.- 5. Wie entsteht eine Zwangsstörung?.- 6. Wer kann helfen?.- 7. Was können wir tun?.​​

Igelino lacht nicht mehr: Depressionen kindgerecht erklärt

by Lisa Pongratz

Jedes Buch der Serie vom kleinen Igel Igelino thematisiert eine häufige psychische Erkrankung im Kindesalter. Die Geschichten und Erklärungen sind auf kindgerechte, enttabuisierende Weise gestaltet.Mit diesem Ratgeber erhalten Eltern und Angehörige die Möglichkeit, mit Hilfe der Geschichte von Igelino, ihren noch jungen Kindern altersgerecht die menschliche Psyche im Falle einer Depression verständlich zu machen. Hierbei liegt der Fokus jedoch nicht nur auf der eigenen Erkrankung bzw. den eigenen Symptomen, sondern auch in der Vermittlung von Wissen über psychische Störungen bei Familienmitgliedern, Freund*innen oder Klassenkamerad*innen mit Verhaltensauffälligkeiten.Eltern erhalten darüber hinaus wichtige grundlegende Informationen zur psychischen Störung, Tipps, wie eine solche Störung erkannt (und von anderen Verhaltensauffälligkeiten abgegrenzt) werden kann, wie man sich gegenüber Betroffenen verhält, sowie Informationen über Therapiemöglichkeiten und Anlaufstellen für Hilfsangebote.

Igelino und das Schlummermonster: Schlafstörungen und Albträume kindgerecht erklärt

by Lisa Pongratz

Jedes Buch der Serie vom kleinen Igel Igelino thematisiert eine häufig vorkommende psychische Erkrankung im Kindes- und Jugendalter. Die Geschichten und Erklärungen sind auf kindgerechte, enttabuisierende Weise gestaltet und von einem jungen, künstlerischen Talent illustriert.Mit diesem Ratgeber erhalten Eltern und Angehörige die Möglichkeit, ihren noch jungen Kindern mit Hilfe der Geschichte von Igelino die menschliche Psyche im Falle einer Schlafstörung altersgerecht verständlich zu machen. Hierbei liegt der Fokus jedoch nicht auf der eigenen Erkrankung bzw. den eigenen Symptomen, sondern auch in der Vermittlung von Wissen über psychische Störungen bei Familienmitgliedern, Freund*innen oder Klassenkamerad*innen mit Verhaltensauffälligkeiten.Eltern erhalten darüber hinaus wichtige grundlegende Informationen zur psychischen Störung, Tipps, wie eine solche Störung erkannt (und von anderen Verhaltensauffälligkeiten abgegrenzt) werden kann, wie man sich gegenüber Betroffenen verhält, sowie Informationen über Therapiemöglichkeiten, Anlaufstellen für Hilfsangebote und eigenständig durchführbare Interventionen in Form von Ressourcenübungen.​1. Psychische Störungen: Zahlen und Fakten.- 2. Tipps zum gemeinsamen Lesen.- 3. Igelino und das Schlummermonster.- 4. Was ist eine Schlafstörung ?- 5. Wie entsteht eine Schlafstörung?- 6. Wer kann helfen?- 7. Was können wir tun?

Igelino und der Angsthase: Angststörungen und Phobien kindgerecht erklärt

by Lisa Pongratz

Jedes Buch der Serie vom kleinen Igel Igelino thematisiert eine häufig vorkommende psychische Erkrankung im Kindes- und Jugendalter. Die Geschichten und Erklärungen sind auf kindgerechte, enttabuisierende Weise gestaltet und von einem jungen, künstlerischen Talent illustriert.Mit diesem Ratgeber erhalten Eltern und Angehörige die Möglichkeit, ihren noch jungen Kindern mit Hilfe der Geschichte von Igelino die menschliche Psyche im Falle einer Angststörung altersgerecht verständlich zu machen. Hierbei liegt der Fokus jedoch nicht auf der eigenen Erkrankung bzw. den eigenen Symptomen, sondern auch in der Vermittlung von Wissen über psychische Störungen bei Familienmitgliedern, Freund*innen oder Klassenkamerad*innen mit Verhaltensauffälligkeiten.Eltern erhalten darüber hinaus wichtige grundlegende Informationen zur psychischen Störung, Tipps, wie eine solche Störung erkannt (und von anderen Verhaltensauffälligkeiten abgegrenzt) werden kann, wie man sich gegenüber Betroffenen verhält, sowie Informationen über Therapiemöglichkeiten, Anlaufstellen für Hilfsangebote und eigenständig durchführbare Interventionen in Form von Ressourcenübungen.1. Psychische Störungen: Zahlen und Fakten.- 2. Tipps zum gemeinsamen Lesen.- 3. Igelino und der Angsthase.- 4. Was ist eine Angststörung/Phobie?- 5. Wie entsteht eine Angststörung/Phobie?- 6. Wer kann helfen?- 7. Was können wir tun?​

Igelino und der wilde Welpe: Aggressives Verhalten kindgerecht erklärt

by Lisa Pongratz

Jedes Buch der Serie vom kleinen Igel Igelino thematisiert eine häufig vorkommende psychische Erkrankung im Kindes- und Jugendalter. Die Geschichten und Erklärungen sind auf kindgerechte, enttabuisierende Weise gestaltet und von einem jungen, künstlerischen Talent illustriert.Mit diesem Ratgeber erhalten Eltern und Angehörige die Möglichkeit, ihren noch jungen Kindern mit Hilfe der Geschichte von Igelino die menschliche Psyche im Falle aggressives Verhaltens (Störung des Sozialverhaltens, komplexe Traumatisierungen, Mobbing, Pubertät und Persönlichkeitsstörungen) altersgerecht verständlich zu machen. Hierbei liegt der Fokus jedoch nicht auf der eigenen Erkrankung bzw. den eigenen Symptomen, sondern auch in der Vermittlung von Wissen über psychische Störungen bei Familienmitgliedern, Freund*innen oder Klassenkamerad*innen mit Verhaltensauffälligkeiten.Eltern erhalten darüber hinaus wichtige grundlegende Informationen zur psychischen Störung, Tipps, wie eine solche Störung erkannt (und von anderen Verhaltensauffälligkeiten abgegrenzt) werden kann, wie man sich gegenüber Betroffenen verhält, sowie Informationen über Therapiemöglichkeiten, Anlaufstellen für Hilfsangebote und eigenständig durchführbare Interventionen in Form von Ressourcenübungen.​1. Psychische Störungen: Zahlen und Fakten.- 2. Tipps zum gemeinsamen Lesen.- 3. Igelino und der wilde Welpe.- 4. Was ist aggressives Verhalten?- 5. Wie entsteht aggressives Verhalten?- 6. Wer kann helfen?- 7. Was können wir tun?

IGFs:Local Repair and Survival Factors Throughout Life Span

by David Clemmons Iain C.A.F. Robinson

Insulin-like growth factors (IGFs), their binding proteins and their receptors play important roles in regulating growth, metabolism, proliferation and survival for many cells and tissues throughout lifespan in humans and other species. Circulating IGF1 is known to be an endocrine regulator, with metabolic effects related to, and partly convergent with, insulin signalling. IGF1 also mediates many of the growth promoting effects of GH, and there is an ongoing debate as to the relative contributions of endocrine-, vs locally-derived IGF1 for systemic growth. More recently however, it has become clear that IGFs may be key local growth and cellular survival factors for many different tissues, active from early in embryonic development, essential for normal maturation and growth during foetal life. IGFs continue to play important roles throughout adult life in many diverse processes such as tissue repair, cellular proliferation, tissue remodelling and metabolic regulation. IGF systems are tightly regulated; orderly control of cellular repair and metabolism is central to healthy ageing, whilst uncontrolled proliferation can lead to cancer.

IgG4-Related Disease

by Kazuichi Okazaki

IgG4-related disease is a new systemic disease that has only recently been identified and characterized. However, most clinical practitioners are not yet familiar with it and thus are likely to misdiagnose it. The purpose of this book is to raise awareness of this disease and its diagnostic pitfalls. A wealth of radiological and histopathological images helps clinicians to understand its characteristics in various organs as well as their clinical and basic medical backgrounds. All of the authors are experts who have published numerous important papers in the field. This book will be useful to physicians in various disciplines such as gastroenterology, rheumatology, ophthalmology, otolaryngology, urology, hematology, and respiratory medicine, not only as a textbook but as an authoritative and comprehensive reference work as well.

IgG4-Related Disease

by Hisanori Umehara Kazuichi Okazaki John H. Stone Shigeyuki Kawa Mitsuhiro Kawano

IgG4-related disease is a new systemic disease that has only recently been identified and characterized. However, most clinical practitioners are not yet familiar with it and thus are likely to misdiagnose it. The purpose of this book is to raise awareness of this disease and its diagnostic pitfalls. A wealth of radiological and histopathological images helps clinicians to understand its characteristics in various organs as well as their clinical and basic medical backgrounds. All of the authors are experts who have published numerous important papers in the field. This book will be useful to physicians in various disciplines such as gastroenterology, rheumatology, ophthalmology, otolaryngology, urology, hematology, and respiratory medicine, not only as a textbook but as an authoritative and comprehensive reference work as well.

IgG4-Related Kidney Disease

by Takao Saito John H. Stone Hitoshi Nakashima Takako Saeki Mitsuhiro Kawano

This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4RKD). IgG4-related disease (IgG4RD), which is characterized by an elevated serum IgG4 level and infiltration of systemic organs by IgG4 positive plasma cells, is a newly recognized systemic disease. Diverse renal manifestations including specific tubulointerstitial nephritis, membranous nephropathy, and tumor-like urological diseases extending to the pelvis and urinary tract in IgG4RD have been reported and are recently attracting attention as IgG4RKD. In this book, leading researchers in the field present the latest insights into the broad spectrum of IgG4-RKD characteristics. In addition, they provide a detailed explanation of the pathology of IgG4-RKD including comparisons between the kidney and other affected organs, such as the lacrimal, salivary glands and pancreas in the histopathological section. IgG4-Related Kidney Disease will have a major impact on future immunological and nephrological studies and offers a useful resource not only for nephrologists but also general physicians and investigators in related fields.

IgG4-Related Sclerosing Cholangitis

by Terumi Kamisawa Myung-Hwan Kim

This book aims to raise awareness of IgG4-related sclerosing cholangitis among practicing physicians and to equip readers with a sound understanding of the principles of diagnosis and treatment. Clinical, serological, and histopathological features are clearly described and imaging appearances on all relevant modalities are illustrated, covering the bile duct and other involved organs. Differential diagnosis from other diseases, including primary sclerosing cholangitis and cholangiocarcinoma, is precisely explained. Information is then presented on all significant current and emerging therapeutic strategies, including steroids, immunosuppressive drugs, and rituximab. Finally, attention is drawn to significant prognostic features. While IgG4-related sclerosing cholangitis is now a widely acknowledged condition, most practitioners are still liable to misdiagnose it owing to a lack of familiarity with its presenting features. This book should help to rectify the situation and will be an asset for all who may encounter the disease in clinical practice.

Igniting the Power of Community

by Paul A. Gaist

Igniting the Power of Community: The Role of CBOs and NGOs in Global Public Health introduces readers to the pursuit and potential of community-based organizations and nongovernmental organizations to transform global public health. At a time of unprecedented challenges, economic crises, social inequalities, environmental stressors, emerging health threats, these organizations are initiating and driving change, often being the first to call attention to the issues and increasingly forging significant and sustainable solutions. Through concrete examples, success stories, and cautionary tales from experienced practitioners, Igniting the Power of Community demonstrates why understanding the roles of the diverse organizations of this sector is vital to anyone concerned with improving health and public health today. This forward-thinking book explains how citizen sector organizations work, their immediate and long term impact on public health, and the key players and business dynamics involved. With an emphasis on innovative approaches, it provides an "insiders view" into practical considerations regarding organizational structure, financing, and operations. A sampling of the coverage: The new era of social entrepreneurship and philanthropy Sustainability in international public health NGOs Front-line perspectives from both well-established and grassroots CBOs Faith-based organizations and public health NGOs and the military: evolving relationships in conflict and disaster zones Understanding the environmental health movement and its impact Project YEAH: a youth AIDS organizations story. Whether you are involved in clinical care, health research, public health programs, or policy development and implementation, this book provides key insights and skills, and will serve as an invaluable resource in working most effectively with and within these dynamic organizations. body>

IgY-Technology: Basic Knowledge for a Successful Practice

by Xiao-Ying Zhang Ricardo S. Vieira-Pires Patricia M. Morgan Rüdiger Schade

This first edited Volume on IgY-Technology, addresses the historical and dynamic development of IgY-applications. The authors cover the biological basis and theoretical context, methodological guidance, and applications of IgY-Technology. A focus is laid on the use of IgY-antibodies for prophylactic/therapeutic purposes in human and veterinary medicine. Aside from applications, the chapters also offer an evolutionary understanding of the IgY molecule, IgY receptors and practical prerequisites to produce IgY-antibodies. Guidance is given for every step of the process. Starting with an introduction to hens as a model species and including hen husbandry, hen egg-laying capacity and total IgY outcomes. Readers will also learn about immunization techniques, the advantages and limitations of different IgY extraction methods, as well as storage stability of the final product. The last part of the volume highlights hands-on aspects of applications, such as IgY delivery strategies, new methods to produce monoclonal IgY-antibodies or production of functional IgY fragments by phage-display as well as commercial exploitation of the technology. Thus, this book is a valuable resource and guide for Scientists, Clinicians and Health Product Developers in both human and veterinary medicine.

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