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The Imaginations of Unreasonable Men: Inspiration, Vision, and Purpose in the Quest to End Malaria
by Bill ShoreA small cadre of scientists-collaborators and competitors-are determined to develop a vaccine for malaria-a feat most tropical disease experts have long considered impossible. Skepticism, doubt, and a host of logistical and financial obstacles dog their quest. Success may ultimately elude them. Why, and how, do they persist? Bill Shore is a writer, philanthropist, and business leader who knows from personal experience the rare and elusive nature of transformative innovation. In this moving and inspiring book, the story of these uncompromising scientists serves as springboard for his passionate inquiry into the character and moral fabric of those who devote their lives to solving the world’s most pressing and perplexing problems. What does it take to achieve the impossible? It takes whatever it takes.
Imagine You Are An Aluminum Atom: Discussions With Mr. Aluminum
by Christopher ExleyJoin "Mr. Aluminum," a scientist who has made the study of aluminum his life's work, on a journey of discovery, reflection, and the science of aluminum. Professor Christopher Exley is a firm believer that science is only useful when it is properly communicated. Scientific papers are difficult vehicles for the wider communication of science and thus he has always endeavored to tell the story of his scientific research as widely as possible through myriad blogs, presentations, and interviews. Through a series of easy-reading entries written for non-scientists, Exley will educate readers about his lifelong scientific passion: aluminum. In scientific circles, aluminum—in relation to human health specifically—has gone the way of the dinosaurs (though, unlike dinosaurs, there has not yet been a popular revival!). Yet aluminum is also the greatest untold story of science. But why do we all need to know a little bit more about aluminum? Do we need a self-help guide for living in what Exley has coined "The Aluminum Age"? What is it about aluminum that makes it different? What about iron, copper, or any of the so-called "heavy metals," like mercury, cadmium, or lead? Why must we pay particular attention to aluminum? Because its bio-geochemistry, its natural history, raises two red flags immediately and simultaneously. These two danger signals are easily missed by all of us and easily dismissed by those whose interests are conflicted by aluminum&’s omnipresence in human life and consequently, are purposely blind to its danger signals. First, aluminum, in all of its myriad forms, is super abundant; it is the third most abundant element (after oxygen and silicon) of the Earth&’s crust. Second, aluminum is super reactive; it is both chemically and biologically reactive. However, these two red flags identify a paradox, as the abundant and biologically reactive aluminum has no biological function either in any organism today nor in any extinct biota from the evolutionary past. This means in practical terms that when we encounter aluminum in our everyday lives, our bodies only see aluminum as an impostor, something foreign, and something for which we have not been prepared through biochemical evolution. This in turn means that all of our encounters with aluminium are adventitious, random, and chaotic. And potentially dangerous. Imagine You Are An Aluminum Atom: Discussions With "Mr. Aluminum" examines the science of aluminum and human health and makes them understandable to all. Within the science you will find personal recollections of events, as well as opinions and reflections upon how the politics of aluminum have influenced and interfered with doing and reporting the science. It is at once both a personal recollection of Exley's life in aluminum research and a guide on the dangers of the constant exposure to aluminum we as humans face during this "Aluminum Age." It will inform, it will provide the means to question the science, and it will, if the reader is prepared to participate, answer those frequently asked questions on aluminum and human health.
Imaging Acute Abdomen in Children
by Fred E. Avni Philippe PetitThis book aims to equip readers with a sound understanding of the imaging strategies that are appropriate in children with acute abdominal conditions. The starting points are the clinical conditions, which are outlined in an introduction presented by pediatrician experts in emergency medicine, and the age groups, with differentiation of children and infants from neonates. The various conditions and their frequency are documented in detail, with clear description and illustration of the presentations on different imaging modalities. A large majority of the included images are from recent examinations and have been obtained using the most up-to-date techniques. The therapeutic impact of imaging is also explained, and the coverage is completed with helpful decision trees and tables of differential diagnosis. At the end of each chapter a concise resume underlines the main points. Imaging Acute Abdomen in Children will be of value for pediatric and general radiologists, radiologists in training, pediatricians, pediatric surgeons, emergency pediatricians, and others with an interest in the subject.
Imaging Acute Neurologic Disease
by Massimo Filippi Jack H. SimonWhile conventional magnetic resonance, X-ray-based, ultrasound, and nuclear medicine techniques are widely used to facilitate diagnosis, inform therapeutic decision-making, provide information regarding prognosis, and monitor therapeutic response in neurologic diseases, their practical value in acute clinical care is not as yet well-defined and the potential future development is not fully appreciated. This book provides a comprehensive survey of best practice for specialists and trainees in neurology, emergency medicine, neuroradiology, radiology, neurosurgery, and critical care. The symptom-based approach guides the choice of the available imaging tools for efficient, accurate, and cost-effective diagnosis to support immediate management of common and complex neurological disorders in the acute setting. Effective examination algorithms are included that integrate neurological and imaging concepts with the practical demands and constraints of emergency care. Written by leading international authorities, the book is extensively illustrated and contains many helpful case-histories.
Imaging and Correlative Physicochemical Techniques
by Alan A. Boulton Glen B. Baker Donald P. BoisvertImaging and Correlative Physicochemical Techniques
Imaging and Diagnosis in Pediatric Brain Tumor Studies
by Monika Warmuth-MetzThis book describes the features in structural imaging of the most important pediatric brain tumors with the aim of enabling radiologists to make the correct differential diagnosis and to provide the pediatric oncologist with all the imaging information relevant to further management. The opening chapter is devoted to the complex subject of pediatric trials at the national and international levels and the importance of staging for stratification, differential treatment, and outcome. A general imaging protocol for children with brain tumors is presented, and individual chapters then identify key points for the differential diagnosis and staging of posterior fossa tumors, low- and high-grade gliomas, germ cell tumors, and craniopharyngiomas. The relevance of aspects such as tumor site and age to diagnosis is explained, and pitfalls associated with meningeal dissemination and treatment-related complications mimicking recurrence are highlighted. The importance of ensuring comparability of follow-up by use of standard MR (or CT) imaging is emphasized. In drawing on the lessons gained both from pediatric trials and from the author's own experience, this book will be invaluable for all radiologists.
Imaging and Focal Therapy of Early Prostate Cancer
by Thomas J. PolascikThis text encompass an up-to-date, comprehensive review of the state-of-the-art for gland preserving therapies. Fully updated and revised, this text evaluates the scientific evidence for the evolving trend to treat intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, focal therapy methods. Various ablative devices such as high intensity focused ultrasound, irreversible electroporation, photodynamic therapy, cryotherapy and laser ablation, among others, is discussed in regard to their strengths and limitations as a therapeutic modality. Emphasis is placed on patient selection and outcomes utilizing both advanced imaging techniques and pathologic evaluation. Current and new approaches to image cancer foci within the prostate (multiparametric ultrasonography, multiparametric magnetic resonance image, etc) are presented along with various biopsy techniques, including robotics to map prostate cancer. Patient selection based on imaging and genomic classification, adjuvants to enhance therapy, treatment strategy, outcomes and patient centered concerns is discussed, providing an acceptable balance between cancer control and improved quality of life for patients. Written by experts in the field and lavishly illustrated with detailed line-art and photographs, Imaging and Focal Therapy of Early Prostate Cancer, Second Edition is designed as a comprehensive resource for urologists, radiation oncologists, medical oncologists, radiologists, uropathologists, molecular biologists, biomedical engineers, other clinicians -- residents, fellows, nurses and allied professionals -- and researchers with an interest in the diagnosis and novel treatment of prostate cancer. It will provide insight into the latest research and clinical applications of image-guided diagnosis and minimally invasive focal, gland-preserving treatment for prostate cancer.
Imaging and Focal Therapy of Early Prostate Cancer
by Thomas J. PolascikImaging and Focal Therapy of Early Prostate Cancer evaluates the scientific evidence for the evolving trend to treat low to intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, focal therapy methods. Various ablative devices such as high intensity focused ultrasound, irreversible electroporation, photodynamic therapy, cryotherapy and laser ablation, among others, are discussed in regard to their strengths and limitations as a therapeutic modality. Emphasis is placed on tumor stage shift towards early stage disease with an increase in unilateral versus bilateral cancers validated by final pathology assessment of large prostatectomy series. Current and new approaches to image cancer foci within the prostate (3-Dimensional contrast-enhanced transrectal ultrasonography, multiparametric magnetic resonance image with spectroscopy, ETC) are presented along with biopsy techniques to map prostate cancer. Patient selection, treatment strategy, outcomes and safety concerns that may provide acceptable cancer control and improved quality of life for patients are all covered in detail. Written by experts in the field and lavishly illustrated with detailed line-art and photographs, Imaging and Focal Therapy of Early Prostate Cancer is a resourceful volume beneficial to practitioners specializing in the treatment and management of prostate cancer.
Imaging and Imagining the Fetus: The Development of Obstetric Ultrasound
by Malcolm Nicolson John E. FlemingHow engineers and clinicians developed the ultrasound diagnostic scanner and how its use in obstetrics became controversial.To its proponents, the ultrasound scanner is a safe, reliable, and indispensable aid to diagnosis. Its detractors, on the other hand, argue that its development and use are driven by the technological enthusiasms of doctors and engineers (and the commercial interests of manufacturers) and not by concern to improve the clinical care of women. In some U.S. states, an ultrasound scan is now required by legislation before a woman can obtain an abortion, adding a new dimension to an already controversial practice. Imaging and Imagining the Fetus engages both the development of a modern medical technology and the concerted critique of that technology.Malcolm Nicolson and John Fleming relate the technical and social history of ultrasound imaging—from early experiments in Glasgow in 1956 through wide deployment in the British hospital system by 1975 to its ubiquitous use in maternity clinics throughout the developed world by the end of the twentieth century. Obstetrician Ian Donald and engineer Tom Brown created ultrasound technology in Glasgow, where their prototypes were based on the industrial flaw detector, an instrument readily available to them in the shipbuilding city. As a physician, Donald supported the use of ultrasound for clinical purposes, and as a devout High Anglican he imbued the images with moral significance. He opposed abortion—decisions about which were increasingly guided by the ultrasound technology he pioneered—and he occasionally used ultrasound images to convince pregnant women not to abort the fetuses they could now see.Imaging and Imagining the Fetus explores why earlier innovators failed where Donald and Brown succeeded. It also shows how ultrasound developed into a "black box" technology whose users can fully appreciate the images they produce but do not, and have no need to, understand the technology, any more than do users of computers. These "images of the fetus may be produced by machines," the authors write, "but they live vividly in the human imagination."
Imaging and Interventional Radiology for Radiation Oncology (Medical Radiology)
by Regina G. H. Beets-Tan Wim J. G. Oyen Vincenzo ValentiniThis book, edited by leading experts in radiology, nuclear medicine, and radiation oncology, offers a wide-ranging, state of the art overview of the specifics and the benefits of a multidisciplinary approach to the use of imaging in image-guided radiation treatments for different tumor types. The entire spectrum of the most important cancers treated by radiation are covered, including CNS, head and neck, lung, breast, gastrointestinal, genitourinary, and gynecological tumors. The opening sections of the book address background issues and a range of important technical aspects. Detailed information is then provided on the use of different imaging techniques for T staging and target volume delineation, response assessment, and follow-up in various parts of the body. The focus of the book ensures that it will be of interest for a multidisciplinary forum of readers comprising radiation oncologists, nuclear medicine physicians, radiologists and other medical professionals.
Imaging and Pathology of Pancreatic Neoplasms
by Mirko D'Onofrio Paola Capelli Paolo PederzoliAlthough interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example. Diagnosis depends on the structure of the pancreatic lesion, which can be directly visualized on US, CT or MR images. This atlas, which encompasses both the imaging and the pathology of pancreatic neoplasms, will therefore be invaluable in enabling radiologists and sonographers to understand the underlying pathology and in allowing pancreatic pathologists to understand the imaging translation. The emphasis in the atlas is very much on the pathological and imaging appearances, with most of the text concentrated at the beginning of the chapters. A comprehensive overview is provided of typical and atypical presentations and diverse aspects of common and uncommon pancreatic neoplasms, including ductal adenocarcinoma, neuroendocrine neoplasms, intraductal papillary mucinous neoplasms, cystic neoplasms, metastases and lymphoma.
Imaging and Pathology of Pancreatic Neoplasms: A Pictorial Atlas
by Mirko D’Onofrio Paola Capelli Paolo PederzoliThe second edition of this atlas focuses on imaging methods and techniques, new diagnostic concepts and therapeutic approaches in management of pancreatic neoplasms. Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, less is known about it than about, for example, liver pathology. Diagnosis depends on the structure of the pancreatic lesion, which can be directly visualized in US, CT or MR images.The book’s focus is very much on the imaging and pathological appearances, with most of the text concentrated at the beginning of the book followed by images gallery. A comprehensive overview is provided of typical and atypical presentations and diverse aspects of common and rare pancreatic tumors, including ductal adenocarcinomas with dedicated chapter to ductal adenocarcinoma downstaging, neuroendocrine neoplasms, cystic pancreatic neoplasms and intraductal papillary mucinous neoplasms. The Verona “Pancreas Centre,” the first institute of its kind in Italy and one of very few in the world, pursues an interdisciplinary approach to treating the problems of this organ, focusing on the patient, on research, and on teaching. A dedicated center that can look back on 40 years of tradition, many of its respected specialists have made essential contributions in surgery, gastroenterology, oncology, pathology, and radiology. Given its scope, this atlas will be an invaluable asset, helping radiologists understand the underlying pathology and helping pancreatic pathologists understand the imaging translation.
Imaging and Quantifying Neuronal Autophagy (Neuromethods #171)
by Ben Loos Esther WongThe volume aims to explore the dynamic nature of the autophagy pathway, and the latest techniques that allow researchers to capture and quantify this process in neurons. The chapters in this volume cover topics such as fundamental, historical, and functional approaches that began in baker’s yeast; Saccharomyces cerevisiae; the role of both electron microscopy and live-cell imaging using fluorescently tagged autophagy proteins; and the rate of puncta appearance and its correlation with the rate of autophagosome formation. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Imaging and Quantifying Neuronal is a valuable resource that provides insights into the power of microscopy tools, live-cell imaging, and photoactivation and correlative techniques.
Imaging and Technology in Urology
by Steve Payne Kieran O'Flynn Ian EardleyImaging and Technology: Principles and Clinical Applications is a practical and user-friendly consolidated source book for urologists, and urologists in training, regarding the basic science of imaging modalities used on a day-to-day basis in urological practice. Similarly, the intention is to provide an introduction to the technology that is used in the practice of urological surgery and the management of urological patients in the clinical setting. This knowledge level is appropriate for certification for independent consultant practice in urology in the UK. The book is also valuable to urologists and urological trainees outside of the UK and in other surgical specialities.
Imaging and Technology in Urology
by Steve Payne Sotonye Tolofari Dora Moon Benjamin StarmerThis book offers a new edition of the hugely successful title, Imaging & Technology in Urology--Principles and Clinical Applications edited by Steve Payne, Ian Eardley, Kieran O'Flynn in 2012. Essential reading for preparation of exit exams in Urology, it is used worldwide by exam candidates. Fully updated in essential areas of the book following on from recent developments in the last decade, it helps give preparation to candidates. The most comprehensive and reliable source of information on this particular topic.
Imaging and Tracking Stem Cells: Methods and Protocols (Methods in Molecular Biology #2150)
by Kursad TurksenThis fully updated book brings together protocols to arm stem cell biologists with tools and approaches to continue uncovering the intricacies and regulatory mechanisms underlying stem cell biology. Through various models and organ systems, the volume reflects the numerous recent advances in cell lineage and lineage tracking. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Imaging and Tracking Stem Cells: Methods and Protocols, Second Edition is an ideal guide for novices and experts alike who are working to expand our knowledge in the field of stem cells.
Imaging and Urodynamics of the Lower Urinary Tract
by Uday PatelThis book is a practical text covering the imaging techniques and the range of urodynamic problems the trainee and practising urologist is likely to encounter including; congenital abnormalities of the bladder, functional abnormalities of the bladder, intraluminal abnormalities and staging of bladder cancer. The urethra and lower urinary tract are also dealt with. Although these disorders are covered in the major reference works, there is a need for a practical, accessible, user friendly text which provides clear and unambiguous guidelines on the best practice available.
Imaging and Visualization in The Modern Operating Room
by Yuman Fong Pier Cristoforo Giulianotti Jason Lewis Bas Groot Koerkamp Thomas ReinerThis text provides a state of the art overview of tools for guiding surgeons in the modern operating room. The text explains how many modalities in the current armamentarium of radiologic imaging have been brought to the operating room for real time use. It also explains the current use of near infrared, fluorescent, and chemo-luminescent imaging to guide minimally invasive and open surgery to improve outcome. The book is separated into two sections. The first, discusses the biologic principles that underlie novel visualization of normal organs and pathology. The currently available equipment and equipment anticipated in the near future is covered. The second section summarizes current clinical applications of advanced imaging and visualization in the OR. Novel means of visualizing normal anatomic structures such as nerves, bile duct, and vessels that enhance safety of many operations are covered. Novel biologic imaging using radio-labeled and fluorescent-labeled molecular probes that allow identification of inflammation, vascular abnormalities, and cancer are also discussed. Authored by scientists who pioneer research in optics and radiology, tool makers who use this knowledge to make surgical equipment, and surgeons who innovate the field of surgery using these new operative tools, Imaging and Visualization in the Modern Operating Room is a valuable guide for surgeons, residents and fellows entering the field.
Imaging Atlas of Ophthalmic Tumors and Diseases
by J. Matthew DebnamThis atlas describes an array of tumors and diseases that affect the orbit and associated cranial nerves. Often lacking in radiology residency and fellowship training is teaching of the anatomy of the orbit and cranial nerves, as well as the imaging appearance of orbital tumors and diseases that affect these regions. This atlas fills this gap of knowledge with tumors and diseases encountered and treated at MD Anderson Cancer Center, providing a review of the imaging anatomy and the appearance of the tumors and diseases that should aid in formatting a differential diagnosis. The text consists of ten chapters divided into separate anatomic sections followed by an eleventh chapter describing the treated orbit and tumor recurrence. Each of the first ten chapters begins with a description of the relevant anatomy, labeled CT and MRI images and drawings to highlight important anatomic considerations. This is an ideal guide for practicing general radiologists, neuroradiologists and trainees, as well as ophthalmologists, head and neck surgeons, neurosurgeons, medical and radiation oncologists, and pathologists who interpret or review orbital images as part of their daily practice.
Imaging Atlas of the Normal Gallbladder and Its Variants
by J.W. MeilstrupAn in-depth knowledge of the wide spectrum of normal gallbladder appearances is vital to appropriate clinical workup and the correct diagnosis of patients with upper abdominal symptoms. This book covers the range of appearances of the normal gallbladder and its variants, including discussions of anatomy, embryology, and imaging techniques to promote a better understanding of the subject. Anomalies of number, location, and form are each addressed in separate chapters, and discussions of imaging artifacts of the gallbladder and pseudolesions, which can mimic gallbladder disease, are also included. A short chapter on the appearance of the fetal gallbladder is included to round out this comprehensive volume.
Imaging Biomarkers in Epilepsy
by Andrea Bernasconi Neda Bernasconi Matthias KoeppEpilepsy is a prevalent and serious neurological disorder. This vital textbook addresses the role of neuroimaging as a unique tool to provide in vivo biomarkers aimed at furthering our understanding of causes and consequences of epilepsy in a day-to-day clinical context. Unique in its approach, this translational book presents a critical appraisal of advanced pre-clinical biomarkers that allows capturing epileptogenesis at molecular, cellular, and neuronal system levels. The book is divided into four sections. Part I includes a series of chapters focused on imaging of early disease stages. Part II discusses lesion detection and network analysis methods. Part III focuses on imaging methods used to predict response to antiepileptic drugs and surgery. Finally, Part IV presents imaging techniques used to evaluate disease consequence.
Imaging Brain Diseases: A Neuroradiology, Nuclear Medicine, Neurosurgery, Neuropathology and Molecular Biology-based Approach
by Serge Weis Michael Sonnberger Andreas Dunzinger Eva Voglmayr Martin Aichholzer Raimund Kleiser Peter StrasserThis book illustrates in a unique way the most common diseases affecting the human nervous system using different imaging modalities derived from radiology, nuclear medicine, and neuropathology. The features of the diseases are visualized on computerized tomography (CT)-scans, magnetic resonance imaging (MRI)-scans, nuclear medicine scans, surgical intraoperative as well as gross-anatomy and histology preparations. For each disease entity, the structural changes are illustrated in a correlative comparative way based on the various imaging techniques. The brain diseases are presented in a systematic way allowing the reader to easily find the topics in which she or he is particularly interested. In Part 1 of the book, the imaging techniques are described in a practical, straightforward way. The morphological built-up of the normal human brain and its vascular supply are presented in Part 2. The chapters of the subsequent Parts 3 to 10 deal with the following diseases involving the nervous system including: hemodynamic, vascular, infectious, neurodegenerative, demyelination, epilepsy, trauma and intoxication, and tumors. The authors incite the clinician to see the cell, the tissue, the organ, the disorder by enabling him to recognize brain lesions or interpreting histologic findings and to correlate this knowledge with molecular biologic concepts. Thus, this book bridges the gap between neuro-clinicians, neuro-imagers and neuro-pathologists. The information provided will facilitate the understanding of the disease processes in the daily routine work of neurologists, neuroradiologists, neurosurgeons, neuropathologists, and all allied clinical disciplines.
Imaging Brain Function With EEG
by Rodrigo Quian Quiroga Walter FreemanThe scalp and cortex lie like pages of an open book on which the cortex enciphers vast quantities of information and knowledge. They are recorded and analyzed as temporal and spatial patterns in the electroencephalogram and electrocorticogram. This book describes basic tools and concepts needed to measure and decipher the patterns extracted from the EEG and ECoG. This book emphasizes the need for single trial analysis using new methods and paradigms, as well as large, high-density spatial arrays of electrodes for pattern sampling. The deciphered patterns reveal neural mechanisms by which brains process sensory information into precepts and concepts. It describes the brain as a thermodynamic system that uses chemical energy to construct knowledge. The results are intended for use in the search for the neural correlates of intention, attention, perception and learning; in the design of human brain-computer interfaces enabling mental control of machines; and in exploring and explaining the physicochemical foundation of biological intelligence.
Imaging Complications of Gastrointestinal and Biliopancreatic Endoscopy Procedures
by Massimo TonoliniThis practically oriented book illustrates and reviews the imaging appearances of the common and unusual complications that may occur after upper gastrointestinal endoscopy, endoscopic retrograde cholangiopancreatography (ERCP), colonoscopy, polypectomy, stricture dilatation, and stent placement. Detailed attention is devoted to the assessment of complications after percutaneous endoscopic gastrostomy (PEG) positioning, the issues associated with video capsule retention after small bowel capsule endoscopy, and iatrogenic colonic perforations in patients with inflammatory bowel diseases. A dedicated chapter explains the expanding role and possibilities of interventional radiology in the treatment of such complications. The pivotal role of multidetector computed tomography (CT) in the detection and grading of endoscopy-specific iatrogenic complications is highlighted. In addition, normal imaging appearances are presented for comparison and information is provided on such aspects as the mechanisms of complications, patient- and procedure-related risk factors, clinical features, and treatment options according to established guidelines. The book will be invaluable in enabling gastroenterologists, general surgeons, and radiologists to diagnose and treat endoscopy-related complications in timely fashion.
Imaging Coronary Arteries
by David A. Dowe Massimo Fioranelli Paolo PavoneIn non-fatal cases, cardiovascular diseases are associated with a decreased quality of life as well as a substantial economic burden to society. Most sudden cardiac events are related to the complications of a non-stenosing marginal plaque. For this reason, the ability to properly identify the atherosclerotic plaque with rapid, non-invasive techniques is of utmost clinical interest in diagnostic workup and therapeutic planning of symptomatic patient. Nowadays CT produces high-quality images of the coronary arteries, in addition to defining their location and the extent of the atherosclerotic involvement. This new edition is enriched with two important additions. Firstly, dedicated chapters on intravascular ultrasound (IVUS), catheter angiography, and nuclear imaging have been included, with some discussions on theoretical techniques such as optical coherence tomography (OCT) and magnetic resonance imaging (MRI). Secondly, a completely new section comprising more than 70 clinical cases remarkably expands the horizons reached by the previous edition. This volume provides general practitioners and cardiologists with a basic understanding of the imaging techniques. For radiologists with no direct experience in cardiac imaging, the book serves as an important source of information on coronary pathophysiology and anatomy.