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Immobility and Medicine: Exploring Stillness, Waiting and the In-Between
by Cecilia Vindrola-Padros Bruno Vindrola-Padros Kyle Lee-CrossettRecent work in the mobilities literature has highlighted the importance of thinking about mobility and immobility as a continuum, where movement intersects with processes that might entail episodes of transition, waiting, emptiness, and fixity. This focus on stillness, things that are stuck, incomplete or in a state of transition can point to new theoretical, methodological and practical dimensions in social studies of medicine. This edited volume brings the concept of immobility to the forefront of social studies of medicine to explore how immobility shapes processes of medical care and the theoretical and methodological challenges of studying immobility in medical contexts. The authors in this volume draw from a wide range of case studies across the globe to make contributions to our current understanding of health, illness and medicine, mobilities and immobilities.Chapter 2 “Lists in Flux, Lives on Hold? Technologies of Waiting in Liver Transplant Medicine” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Immobilization Strategies: Biomedical, Bioengineering and Environmental Applications (Gels Horizons: From Science to Smart Materials)
by Anuj Tripathi Jose Savio MeloThis book delves into the field of immobilizing biologically active and non-active molecules. It discusses the designing strategy of immobilization and the current state-of-the-art applications for advancing biomedical, agricultural, environmental and industrial practices. It focuses on aspects ranging from fundamental principles to current technological advances at multi-scale levels (macro, micro, and nano) which are suitable for cell, enzyme, and nano-catalyst based applications. Written by experts from across the globe, the contents deal with illustrated examples of molecular and cellular interactions with materials/scaffolds and discussions on factors that can affect the functionality and yield of the process. With its discussions on material science, design of delivery vehicles, separation science, additive manufacturing, agriculture and environmental science, this book will be a useful reference for researchers across multiple disciplines.
Immortal Bird
by Doron Weber"Maybe I've finally beaten this thing, maybe three years' struggle will not have been in vain. Maybe this is finally over . . ." --from Damon's blog, May 2004 A FAMILY' S LOVE lies at the heart of this gifted boy's fight to survive. Born with a congenital heart defect that required surgery when he was a baby, Damon Weber lives a big life with spirit and independence that have always been a source of pride to his parents, Doron and Shealagh. But when Damon is diagnosed with a new illness as a teenager, his triumphant coming-of-age tale turns into a darker and more dramatic quest: his family's race against time and a flawed heath care system.Immortal Bird is a searing account of a father's struggle to save his remarkable son, a story of a young boy's passion for life, and a tribute to his family's love. It is also a story of the perils of modern medicine and the redemptive power of art in the face of the unthinkable.
Immortal Thoughts: Late Style In A Time Of Plague
by Christopher NeveA remarkable, heartfelt, beautifully written analysis of the late work of major artists which author Max Porter has called “completely and utterly marvelous.” In 2020, as the spread of COVID-19 caused pandemonium worldwide,a painter and writer returned to a childhood home to reflect upon the transcendence of nature and the work of the artists he most admires. It seems to Christopher Neve that in their final works—their late style—that they have something remarkable in common. This has more to do with intuition and memory than with rationality or reason. Immortal Thoughts: Late Style in a Time of Plague is an anthology of these reflections. In this personal and moving account, nineteen short essays on artists are interspersed with recollections of the cataclysmic global progress of the disease in poignant contrast to the beauty of the seasons in Neve’s isolated house and garden. From Paul Cézanne and Michelangelo to Rembrandt and Gwen John, Neve dwells on artists’ late ideas, memories, risks, and places in the context of time and mortality. As much art history as a discussion of great art in the context of the “dance of death,” Neve also writes about Pierre Bonnard, Giorgio Morandi, Nicolas Poussin, Chaim Soutine, and many others. Immortal Thoughts is a summary of a lifetime’s contemplation of art.
The Immortalist: A Sci-Fi Thriller
by Scott BritzFor fans of Robin Cook and Michael Crichton comes a medical thriller that melds cutting-edge science with ripped-from-the-headlines terror. What happens when a new immortality drug leads to an explosive outbreak of a deadly virus that, if not contained, could wipe out humanity once and for all?World-renowned virologist Dr. Cricket Rensselaer-Wright abruptly abandoned her research in Africa after watching her colleague die tragically from the Ebola virus. When she returns to the States to reunite with her teenage daughter Emmy, her plans are sidetracked. No sooner does she set foot on the campus of Acadia Springs--the research institute where she grew up and Emmy now lives--than her onetime mentor Charles Gifford announces his discovery of the Methuselah Vector, a gene therapy agent that can confer immortality on a patient after a single injection. Gifford's air of triumph is marred when a young woman on campus dies suddenly from a horrific viral infection, eerily similar to the Ebola that drove Cricket out of Africa. Despite Cricket's pleas to slow down the rollout of the Vector and run more tests, Gifford refuses. And when the unthinkable happens--when Emmy falls ill with the same mysterious disease--Cricket is forced to take matters into her own hands. But is it already too late? Gifford will stop at nothing to release the Vector into the world. Mobs are clamoring for it. Cricket has only a few hours to find a cure for Emmy, and to convince the public that Gifford's quest for eternal life may cost the very lives he hopes to save. **The publisher has provided this ebook to you without Digital Rights Management software (DRM) applied so that you can enjoy reading it on your personal devices.**
Immortality Inc.
by Robert SheckleyA man wakes up after a fatal car accident—in someone else&’s body—in this ahead-of-its-time Hugo Award–nominated classic. Thomas Blaine remembered the car accident that killed him—and then he woke up in the hospital. A nurse told him where he was. &“You&’d call it being in the future.&” A future where bodies are sold to the highest bidder as new homes for the minds of the rich, who are greedy for more life when their own bodies wear out or are damaged. Suddenly, keeping body and soul together has taken on a new, and very sinister, meaning. From the very beginning of his career, Robert Sheckley was recognized by fans, reviewers, and fellow authors as a master storyteller and the wittiest satirist working in the science fiction field. Open Road is proud to republish his acclaimed body of work, with nearly thirty volumes of full-length fiction and short story collections. Rediscover, or discover for the first time, a master of science fiction who, according to the New York Times, was &“a precursor to Douglas Adams.&”
Immortality, Inc.: Renegade Science, Silicon Valley Billions, and the Quest to Live Forever
by Chip WalterThis gripping narrative explores today's scientific pursuit of immortality, with exclusive visits inside Silicon Valley labs and interviews with the visionaries who believe we will soon crack into the aging process and cure death.We live in an age when billionaires are betting their fortunes on laboratory advances to prove aging unnecessary and death a disease that can be cured. Researchers are delving into the mysteries of stem cells and the human genome, discovering what it means to grow old and how to keep those processes from happening. This isn't science fiction; it's real, it's serious, and it's on track to revolutionize our definitions of life and mortality.In Immortality, Inc., veteran science journalist Chip Walter gains exclusive access to the champions of this radical cause, delivering a book that brings together for the first time the visions of molecular biologist and Apple chairman Arthur Levinson, genomics entrepreneur Craig Venter, futurist Ray Kurzweil, rejuvenation trailblazer Aubrey de Grey, and stem cell expert Robert Hariri. Along the way, Walter weaves in fascinating conversations about life, death, aging, and the future of the human race.
Immun, fit und gesund – ohne Medikamente: Über 100 Antworten von Ihrem Arzt
by Daniel HarbsIhr Körper ist Ihnen wichtig? Sie suchen die optimale gesunde Lebensführung? Dieser Ratgeber zu Fitness, Weight Loss, Mental Balance, Beauty, Detox und dem Immunsystem gibt fundierte Tipps. Der Allgemeinmediziner Daniel Harbs antwortet kurz und auf den Punkt auf Fragen, die er in seinem Praxisalltag immer wieder hört.Sie wollen fit werden und bleiben, ohne Medikamente einzunehmen? Verwirrt von den Treffern aus Suchmaschinen? Fragen Sie den Experten. Mit Hamburger Nüchternheit, hanseatischem Humor und verständlichen Worten führt der Autor Sie von den Tipps zum Abnehmen, Mittel gegen den Kater, Abwehr von Stress bis zum Umgang mit Gluten, Fett und Zucker. Und wie können wir uns vor Viren schützen, was macht unser Immunsystem stark? Über 125 Fragen und Antworten decken Ihre Neugier und helfen Ihnen auf dem Weg zu einem selbstbestimmt gesünderen Leben.
Immune: The new book from Kurzgesagt - a gorgeously illustrated deep dive into the immune system
by Philipp Dettmer__________Pre-order now: The first book from the creator of the wildly popular science YouTube channel, Kurzgesagt - In a Nutshell, a gorgeously illustrated deep dive into the immune system that will change how you think about your body forever. 'A truly brilliant introduction to the human body's vast system for fighting infections and other threats'JOHN GREEN, #1 New York Times bestselling author of The Fault in Our Stars'Reads as if it's a riveting sci-fi novel . . . a delightful treat for the curious'TIM URBAN, creator of Wait But Why__________You wake up and feel a tickle in your throat. Your head hurts. You're mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an utterly epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you drink your cup of tea and head out the door.So what, exactly, IS your immune system?Second only to the human brain in its complexity, it is one of the oldest and most critical facets of life on Earth. Without it, you would die within days. In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes readers on a journey through the fortress of the human body and its defences. There is a constant battle of staggering scale raging within us, full of stories of invasion, strategy, defeat, and noble self-sacrifice. In fact, in the time you've been reading this, your immune system has probably identified and eradicated a cancer cell that started to grow in your body.Each chapter delves deeply into an element of the immune system, including defences like antibodies and inflammation as well as threats like viruses, bacteria, allergies and cancer, as Dettmer reveals why boosting your immune system is actually nonsense, how parasites sneak their way past your body's defences, how viruses - including the coronavirus - work, and what goes on in your wounds when you cut yourself.Enlivened by engaging full-colour graphics and immersive descriptions, Immune turns one of the most intricate, interconnected, and confusing subjects - immunology - into a gripping adventure through an astonishing alien landscape.Challenging what you know and think about your own body and how it defends you against all sorts of maladies and how it might also eventually be your own downfall, Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.__________
Immune: The new book from Kurzgesagt - a deep dive into the immune system
by Philipp DettmerA deep dive into the immune system that will forever change how you think about your body - how it works and why it is both your greatest ally and most dangerous enemy - from the creator of the popular science YouTube channel Kurzgesagt - In a Nutshell.'A truly brilliant introduction to the human body's vast system for fighting infections and other threats'JOHN GREEN, #1 New York Times bestselling author of The Fault in Our Stars'Reads as if it's a riveting sci-fi novel . . . a delightful treat for the curious'TIM URBAN, creator of Wait But Why**************You wake up and feel a tickle in your throat. Your head hurts. You're mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an utterly epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you drink your cup of tea and head out the door.So what, exactly, IS your immune system?Second only to the human brain in its complexity, it is one of the oldest and most critical facets of life on Earth. Without it, you would die within days. In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes listeners on a journey through the fortress of the human body and its defences. There is a constant battle of staggering scale raging within us, full of stories of invasion, strategy, defeat, and noble self-sacrifice. In fact, in the time you've been listening to this, your immune system has probably identified and eradicated a cancer cell that started to grow in your body.Each chapter delves deeply into an element of the immune system, including defences like antibodies and inflammation as well as threats like viruses, bacteria, allergies and cancer, as Dettmer reveals why boosting your immune system is actually nonsense, how parasites sneak their way past your body's defences, how viruses - including the coronavirus - work, and what goes on in your wounds when you cut yourself.Enlivened by immersive descriptions, Immune turns one of the most intricate, interconnected, and confusing subjects - immunology - into a gripping adventure through an astonishing alien landscape.Challenging what you know and think about your own body and how it defends you against all sorts of maladies and how it might also eventually be your own downfall, Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.(P) 2021 Hodder & Stoughton Limited
Immune Cells, Inflammation, and Cardiovascular Diseases (Methods in Signal Transduction Series)
by Shyam S. BansalInflammation, once considered a physiological response to foreign pathogens, is now recognized as a crucial pathological player in the initiation and progression of several chronic diseases, including diabetes, obesity, cancer, Alzheimer’s disease, Parkinson’s disease, and many others. Considering that cardiovascular diseases are a leading cause of death in the United States and worldwide, the identification of critical inflammatory processes is of utmost importance to devising new immune-based therapeutics that can be added to existing regimens. This book provides detailed information on aspects of inflammation and the manner in which immune activation pathways affect the progression of cardiovascular diseases and the repair/regeneration mechanisms of underlying diseased tissues. Key Features Outlines the role that inflammation plays in cardiovascular diseases Describes a paradox – neutralization of cytokines that contribute to cardiovascular disease does not show benefit Summarizes research on a variety of processes and mechanisms contributing to cardiovascular pathology Contributions from an international team of leading cardiologists and cardiovascular immunologists Related Titles Roy, S., et al., eds. Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions (ISBN 978-1-138-19955-2) Kong, A-N. T., ed. Inflammation, Oxidative Stress, and Cancer: Dietary Approaches for Cancer Prevention (ISBN 978-1-138-19984-2) Dick, A., et al. Practical Manual of Intraocular Inflammation (ISBN 978-0-367-38720-4)
Immune Checkpoint Blockade
by Yago Pico de CoañaThis detailed volume describes a series of techniques that are essential for evaluating the efficacy of new checkpoint blockade therapies as well as understanding the mechanisms behind the therapies that have already been approved. Beginning with a section on describing the tumor microenvironment and evaluating the immune system at a systemic level, the book continues by covering functional assays that provide answers to questions that may be raised after studying the immune system and its responses to immunotherapies, as well as the use of animal models in this research. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Immune Checkpoint Blockade: Methods and Protocols serves to aid researchers in furthering our understanding of checkpoint blockage as well as the study of tumor immunology and the development of new immunotherapies.
Immune Hematology: Diagnosis And Management Of Autoimmune Cytopenias
by Jenny M. DespotovicThis text provides a concise yet comprehensive overview of the most common autoimmune cytopenias affecting adults and children. The book is divided into four sections, each of which focuses on a major autoimmune cytopenia. The first section features background, pathophysiology, presentation, evaluation, and treatment strategies for immune thrombocytopenia (ITP), the most common cause of antibody-mediated platelet destruction. The second section reviews common forms and treatment strategies for autoimmune hemolytic anemia (AIHA), including a chapter dedicated specifically to Evans Syndrome. The third section comprehensively reviews the pathophysiology, diagnosis and current management approaches to thrombotic thrombocytopenic purpura (TTP), a potentially life-threatening autoimmune syndrome. The book concludes with a final section on autoimmune neutropenia. Each section includes a review of common underlying systemic autoimmune conditions and immune deficiency syndromes that can accompany or cause autoimmune cytopenias.Written by experts in each content area, Immune Hematology: Diagnosis and Management of Autoimmune Cytopenias is a valuable resource for clinicians and professionals who treat patients afflicted with autoimmune cytopenias, including primary care providers, hematologist/oncologists, immunologists, among others.
Immune Homeostasis: Methods and Protocols (Methods in Molecular Biology #2782)
by Vijay KumarThis volume discusses different aspects of immune homeostasis regulation and its dysregulation during various diseases, including infections, cancers, neurodegenerative diseases, autoinflammation, autoimmune diseases, and immunodeficiency, along with immunological, genetic, cell biology, and molecular biology techniques designed to understand immune homeostasis at different stages. The chapters in this book cover topics such as T cell subsets; monocyte-myofibroblast immunomodulation in a 3D co-culture system; human peripheral blood mononuclear cells in patients with neurodegenerative diseases; and CRISPR-Cas9 induced gene-editing in primary human monocytes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Immune Homeostasis: Methods and Protocols is a valuable resource for both novice and experts researchers interested in learning more about this important and developing field.
Immune Homeostasis
by Michael J. Lenardo Andrew L. SnowMany questions remain unresolved as researchers continue to characterize and define the nature of normal immune homeostasis and determine how these processes are dysregulated in immunodeficiency, as well as in autoimmune and lymphoproliferative disorders. Immune Homeostasis: Methods and Protocols focuses on experimental techniques for measuring and analyzing immune cell dynamics, with a particular emphasis on examining lymphocyte programmed cell death in different contexts. With contributions by leading experts in the field, the collection examines detailed protocols for studying various pathways of apoptosis and necrosis in different types of hematopoietic cells, both in vitro and in vivo, methods for studying the maintenance of lymphocyte populations in the steady-state or following infectious challenges in both mice and humans, and technical insights into state-of-the-art genomics tools, among other topics. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Valuable and easy to use, Immune Homeostasis: Methods and Protocols serves as an important toolkit for basic and clinical scientists interested in examining various aspects of immune homeostasis in both normal and disease-related contexts in order to further study the dynamic processes that contribute to homeostasis of the immune system.
Immune Infertility
by Walter K.H. Krause Rajesh K. NazThis book offers comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has four sections focusing on Sperm antigens, Antisperm antibodies (ASAs), Clinical impact of ASAs, and Immune contraception, and include contributions from leading experts in these fields. This new edition of the book offers a comprehensive update that reflects the very significant advances in reproductive immunology that have been achieved over the past five years, especially related to the sperm proteome, sperm-egg binding/fusion proteins, gene knockout studies, and immunocontraception. Reproductive immunology continues to be a fast-growing discipline in which new knowledge is emerging almost every day. Immune Infertility is a model source of vital and reliable information on the latest scientific developments in the field. It will be of value for clinicians, scientists, students, residents, and fellows working in reproductive biology, obstetrics and gynecology, and urology.
Immune Infertility
by Walter K.H. Krause Rajesh K. NazThis comprehensive overview of immune reactions inducing fertility disorders in both sexes first describes the nature and the function of sperm antigens which are capable to induce immune infertility as well as the methods to analyse and characterize these antigens. Secondly, the nature, the origin and induction of antisperm antibodies (ASA) in both sexes and the role of reproductive organs and their interaction with the immune system will be discussed. A large section of the book, which is most important for clinicians working in reproductive medicine, deals with the clinical impact of the immune reaction in reproductive medicine, including the methods of determination and the treatment in immune infertility. Closely related to immune infertility is the development of immune contraceptives which is also discussed.
Immune-Mediated Myopathies and Neuropathies: Current Trends and Future Prospects
by Balan Louis GasparThe book covers all aspects of immune-mediated diseases of the muscle and nerve, which are a group of complex diseases, whose diagnosis needs a team of specialists in the field of neuropathology, immunopathology, neurology, and rheumatology. Nerve and muscle biopsy evaluation is invaluable in distinguishing immune-mediated from etiologies and therefore, despite being invasive, pathological evaluation of nerve and muscle has stood the test of time. Chapters cover all the essential aspects of each disease entity viz. the pathogenesis, clinical features, diagnostic armamentarium, and guidelines for diagnosis and management. It is supplemented with full-colorful illustrations and photomicrographs for better comprehension. It includes a chapter highlighting the current progress in the field of immune-mediated myopathies and neuropathies as it is a rapidly evolving field with the addition of many new entities.This clinically oriented book serves as a primer for general histopathologists as well as a practice guide for neuropathologists. It is also relevant for neurologists and rheumatologists and encourages young medical students, residents, and research scholars in the field of neuropathology, neurology, and rheumatology to get involved in active research.
Immune Mediators in Cancer: Methods and Protocols (Methods in Molecular Biology #2108)
by Ivana Vancurova Yan ZhuThis book provides a comprehensive collection of classic and cutting-edge methodologies as well as bioinformatics and genome-editing approaches that are used to quantify immune mediators and analyze their function and biological activity in cancer cells and tissues. Beginning with a section on the detection of immune mediators in samples, the volume continues with sections covering cytokine bioassays, the expression and regulation of immune mediators in cancer cells, and methods to navigate the enormous datasets created by modern DNA and RNA sequencing and proteomic technology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and wide-ranging, Immune Mediators in Cancer: Methods and Protocols serves as a valuable resource for biochemists, molecular biologists, cancer biologists, and immunologists, as well as for physician-scientists working in the field of immunology and cancer research.
Immune Modulating Agents
by Thomas F. KresinaDiscussing the systemic immune response in the contexts of health, disease, and therapy, this unique resource-the only broadly based book of its kind available on the subject-offers comprehensive examinations of the pathways and agents that affect the human immune response and provides state-of-the-art presentations on practical methods of immune modulation. Focuses on the immune response and modulation in infectious diseases, such as HIV, hepatitis, and parasitic infections and highlights immune modulating agents in gastrointestinal diseases, sepsis, cancer, and autoimmunity! Written by over 50 international authorities representing distinguished institutions in nine countries, Immune Modulating Agentsintroduces basic immunoregulatory mechanisms as homeostasis details cytokines, cellular and humoral immune responses, and hematopoiesis describes neuroendocrine - immune system interactions and the role of psychological stress on immune competence delineates factors that influence disease susceptibility, including nutrition covers drug delivery systems, gene therapy, organ transplantation, arthritis treatment, and vaccination strategies shows how to design clinical trials using immune modulating agents and more!
Immune Modulation and Anti-Inflammatory Therapy in Ocular Disorders
by Uwe Pleyer Jorge L. Alió Talin Barisani-Asenbauer Phuc Le Hoang Narsing A. RaoThese guidelines, compiled by a panel of clinicians and scientists with a high level of expertise, aim to provide readers with the most up-to-date and comprehensive instructions on the treatment and prevention of ocular inflammation. All of the recommendations are explicitly linked to supporting evidence and graded according to the strength of that evidence and the editors have made every effort to ensure that chapters are of a consistently high methodological quality. The guidelines for each treatment include dose and the frequency and mode of delivery. Significant side-effects of treatment are identified and distinguished from those of the disease in question. Suggestions are presented for the prevention both of the disease itself and of the treatment-related complications. In addition, likely future directions in treatment and prevention are identified. These guidelines will be of great practical value for all clinicians and clinical scientists with an interest in the subject.
Immune Reactions and Experimental Models in Rheumatic Diseases: Proceedings of the Fourth Canadian Conference on Research in the Rheumatic Diseases Toronto, October 15-17, 1970
by Duncan A. GordonThe proceedings of the fourth Canadian conference on research in the rheumatic diseases held in Toronto in October 1970, this volume includes some 50 papers based on recent research carried out in Canada, the US, and abroad. The papers centre on two main themes: immunological aspects of the rheumatic diseases, and animal and experimental model diseases which have certain features in common with human rheumatic disorders.
Immune Receptors
by James W.D. Booth Jonathan P. RastImmunology has made significant progress in the past decade, driven forward by rapidly advancing technology and a renewed interest in the vast realm of innate immunity. The receptors that mediate these functions are at the front lines of both protective and regulative roles of the immune system. In Immune Receptors: Methods and Protocols, expert researchers present a variety of experimental approaches to the characterization of immune receptors and the cell biology that mediates their functions. These include imaging techniques that aim to understand receptor localization and trafficking, techniques to measure receptor-ligand interactions, strategies to identify novel ligands and methods to analyze downstream receptor signaling, as well as strategies for genomic and proteomic characterization of receptor repertoires. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Immune Receptors: Methods and Protocols offers technical descriptions and protocols that will be useful both to investigators who are interested in carrying out these procedures and to those who seek a deeper understanding of the bench science that lies behind the immunology literature.
Immune Receptors: Methods and Protocols (Methods in Molecular Biology #2421)
by Jonathan Rast Katherine BuckleyThis volume explores immune cell receptors that are used in the detection of microbes, either by binding directly to non-self molecules or through indirectly sensing microbe-associated cellular disturbances. The chapters in this book cover methods for studying receptor-ligand interactions at both molecular and cellular levels; methods to create and characterize novel antibody reagents; and methods to characterize the molecular processes that lead to adaptive receptor maturation. This book also contains chapters that look at high-throughput strategies that describe the diversity of immune receptors and cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and authoritative, Immune Receptors: Methods and Protocols, Second Edition is a valuable resource for scientists and researchers interested in learning more about this developing field.
Immune Resilience: The Breakthrough Plan to Protect Your Body and Fight Disease
by Romilly HodgesA sweeping look at the complexity of our immune system, with a natural, science-based program to help protect against viruses and other pathogens.Some people can fight off infections relatively easily, with minor symptoms, while others suffer severely. But these outcomes—and our immune responses against them—aren&’t fixed; we can build immune resilience. But how? The answer goes beyond popping vitamin C and zinc during flu season. As clinical nutritionist Romilly Hodges reveals, our immune system is intricate and multifaceted, and powerfully impacted by what we eat, as well as by our lifestyle routines. Immune Resilience offers a fascinating tour of the incredible ways our bodies protect us against disease, with assessments throughout to help the reader identify their weak areas. Then it outlines a personalized, step-by-step program blending defense-building foods with lifestyle strategies, including important advice on movement, sleep, and stress-relief. This book explains: • the connection between sleep and immune memory • how you can harness the power of gentle fasting • why good germs increase immunity and decrease allergies and asthma • how to prepare nutrient-packed meals, with recipes • what kind of exercise boosts immunity, and more With easy-to-reference guidelines for specific infections and a curated guide to the supplements you really need, this essential book helps you put your health in your own hands.