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Infusion Therapy: For Pain, Headache and Related Conditions
by Alaa Abd-ElsayedThere is a significant gap in current knowledge about infusion therapy for treating different pain, headache and psychiatric conditions. Infusion therapy is now a common practice but there is considerable variation in how the therapy is implemented in different centers which can be both dangerous, if high doses are given, or ineffective, if low doses are given. This book provides a practical guide to infusion therapy for clinicians on how to safely and effectively perform this kind of therapy. Chapters cover the pharmacology of each medication and evidence in literature regarding indications, contraindications and doses. A recommended algorithm is provided for patient selection, doses, infusion technique/doses and appropriate monitoring. Infusion Therapy is the first comprehensive, clinical guide to this practice and is an invaluable resource for clinicians in anesthesia, pain medicine, internal medicine and palliative care. It will also be of interest to researchers and pharmacologists who would like to find out how clinicians use infusions.
Infusion Therapy Made Incredibly Easy! (Incredibly Easy! Series®)
by Lippincott Williams WilkinsGet a thorough grounding in delivering safe, effective infusion therapy with the friendly support and technical guidance of the newly updated Infusion Therapy Made Incredibly Easy!®, 5th edition. This complete how-to on administering and monitoring different IV medications delivers clear direction on vital concepts, terms, and techniques—backed by numerous illustrations, confidence-building humor, and expert insights. Offering clear, concise direction for nursing students, this popular Incredibly Easy!® text is also the ideal refresher for nurses and all practitioners learning best practices for a range of infusion therapies.
Inguinal Hernia: Pathophysiology and Genesis of the Disease
by Giuseppe AmatoThis book aims at filling a gap in relation to the pathophysiology of the inguinal region and the genesis of groin protrusions. While inguinal hernia is a widespread disease and hernia repair accounts for the most frequently performed surgical procedure, these two aspects have been unsatisfactorily investigated, so that to date there is no shared hypothesis on how visceral protrusion through inguinal barrier occur. Exact knowledge on the pathogenesis is fundamental for adequately managing a disease, otherwise all curative approaches would not be evidence-based, but merely empirically identified and with uncertain outcomes carried out. Moreover, in absence of pathogenetic certainty, formulating guidelines simply results in an unjustified methodology harbinger of polemics and controversies. Previous studies concerning the pathogenesis of inguinal protrusions were mainly focused on the detection of biochemical changes, mostly related to collagen chains, metalloproteinase and similar elements. Nevertheless, despite decades of researches, a sure relationship between these ultrastructural modifications and visceral protrusion has not been proven. On the contrary, over the years very few investigations dealt with evidencing eventual modifications in the tissue structures of the herniated groin. An extensive research finalized to ascertain in patients and in cadavers structural changes of the tissue elements composing the groin was therefore carried out by the author and his researchers team. The findings of these studies resulted to be very useful for definitely evidencing the etiology of inguinal hernia disease. Overall, the proposed book scrutinizes and widens all emerging aspects related to pathogenesis, histology, physiology, surgical and functional anatomy of the inguinal area affected by hernia protrusion. It intends to be a reference guide to surgeons willing to better understand the structural modifications occurring in patients affected by this disease with the aim of improving treatment results.
Inguinal Hernia Surgery
by Giampiero CampanelliThis book, which describes in detail the most common procedures employed in inguinal hernia surgery, is exceptional in reflecting fully the most recent advances, as well as the most established techniques, in knowledge and practice. The role of recently developed and emerging technologies, including robotics, minimally invasive surgery, and biological meshes, is clearly explained, highlighting useful tips and tricks. The descriptions of traditional procedures, such as the Lichtenstein repair, are brought fully up to date and take into account the novel perceptions that professionals have of them, for example regarding the important role of nurses. The reader will also find guidance on established and new treatments for specific pain conditions, including postoperative chronic pain, the pubic inguinal pain syndrome, and obscure groin pain in women. The need for such an update on inguinal hernia surgery became clear at the 1st World Conference on Abdominal Wall Hernia Surgery, which highlighted the huge differences in the approaches adopted by scientists around the world and was chaired by the editor of this book. Inguinal Hernia Surgery will be a useful tool for all health care practitioners involved in hernia surgery.
Inhalation Aerosols: Physical and Biological Basis for Therapy, Third Edition (Lung Biology in Health and Disease #1)
by Anthony J. Hickey Heidi M. MansourInhalation aerosols continue to be the basis for successful lung therapy for several diseases, with therapeutic strategies and the range of technology significantly evolving in recent years. In response, this third edition takes a new approach to reflect the close integration of technology with its application. After briefly presenting the general considerations that apply to aerosol inhalation, the central section of the book uses the focus on disease and therapeutic agents to illustrate the application of specific technologies. The final integrated strategies section draws the major points from the applications for disease targets and drug products.
Inhalation Toxicology
by Sidney A. Katz Harry SalemThe lungs provide a significant opportunity for the introduction of both therapeutic and toxic chemicals into the human body. In occupational and domestic environments, hazardous chemicals can enter the body through the lungs via gases, aerosols, and particulates from natural and anthropogenic sources. Fully updated with new research and discoverie
Inhaled Delivery Systems for the Treatment of Asthma and COPD
by Donald A. Mahler Rajiv DhandInhaled therapies form the cornerstone for treatment of patients with asthma and COPD. Evolving technology has resulted in availability of a wide range of devices for delivery of inhaled drugs. The four different delivery systems -- pressurized metered-dose inhalers, slow mist inhalers, dry powder inhalers, and nebulizers -- are unique in design and require distinct inhalational instructions for correct use. This book provides current information about inhalation devices, including their advantages and disadvantages, with guidance for optimal techniques of use. The book emphasizes appropriate selection of inhalation devices based on patient and health care professional factors as well as device attributes that allow selection of the right medication in the right inhalation device at the right time for the right patient. Key Features:• Addresses the objective of precision medicine – the right medication in the right inhaler device at the right time.• Inputs by international thought leaders who have published widely on inhaled medications and/or inhaled delivery systems for clinicians, trainees and respiratory therapists.• Discusses the development of audio-based systems and smart inhalers for patient monitoring.
The Inheritance: A Family on the Front Lines of the Battle Against Alzheimer's Disease
by Niki KapsambelisAn inspiring race against time: The courageous, hopeful story of the one family who may hold the key to finding a cure for Alzheimer’s disease.Every sixty-nine seconds, someone is diagnosed with Alzheimer’s disease. Of the top ten killers, it is the only disease for which there is no cure or treatment. For most people, there is nothing that they can do to fight back. But one family is doing all they can. The DeMoe family has the most devastating form of the disease that there is: early onset Alzheimer’s, an inherited genetic mutation that causes the disease in 100 percent of cases, and has a 50 percent chance of being passed onto the next generation. Of the six DeMoe children whose father had it, five have inherited the gene; the sixth, Karla, has inherited responsibility for all of them. But rather than give up in the face of such news, the DeMoes have agreed to spend their precious, abbreviated years as part of a worldwide study that could utterly change the landscape of Alzheimer’s research and offers the brightest hope for future treatments—and possibly a cure. Drawing from several years of in-depth research with this charming and upbeat family, journalist Niki Kapsambelis tells the story of Alzheimer’s through the humanizing lens of these ordinary people made extraordinary by both their terrible circumstances and their bravery. Their tale is intertwined with the dramatic narrative history of the disease, the cutting-edge research that brings us ever closer to a possible cure, and the accounts of the extraordinary doctors spearheading these groundbreaking studies. From the oil fields of North Dakota to the jungles of Colombia, this incredible narrative redefines courage in the face of one of the most pervasive and mysterious pandemics of our time.
Inheritance
by Sharon MoalemAward-winning physician and New York Times bestselling author Sharon Moalem, MD, PhD, reveals how genetic breakthroughs are completely transforming our understanding of both the world and our lives.INHERITANCEConventional wisdom dictates that our genetic destiny is fixed at conception. But Dr. Moalem's groundbreaking book shows us that the human genome is far more fluid and fascinating than your ninth grade biology teacher ever imagined. By bringing us to the bedside of his unique and complex patients, he masterfully demonstrates what rare genetic conditions can teach us all about our own health and well-being.In the brave new world we're rapidly rocketing into, genetic knowledge has become absolutely crucial. INHERITANCE provides an indispensable roadmap for this journey by teaching you:-Why you may have recovered from the psychological trauma caused by childhood bullying-but your genes may remain scarred for life.-How fructose is the sugar that makes fruits sweet-but if you have certain genes, consuming it can buy you a one-way trip to the coroner's office.-Why ingesting common painkillers is like dosing yourself repeatedly with morphine-if you have a certain set of genes.-How insurance companies legally use your genetic data to predict the risk of disability for you and your children-and how that impacts the coverage decisions they make for your family.-How to have the single most important conversation with your doctor-one that can save your life.And finally:-Why people with rare genetic conditions hold the keys to medical problems affecting millions.In this trailblazing book, Dr. Moalem employs his wide-ranging and entertaining interdisciplinary approach to science and medicine-- explaining how art, history, superheroes, sex workers, and sports stars all help us understand the impact of our lives on our genes, and our genes on our lives. INHERITANCE will profoundly alter how you view your genes, your health--and your life.side of some of his most complex and unique genetic patients to masterfully demonstrate what uncommon genetic conditions can teach us about our universal health and wellbeing.Turning the nature/nurture debate completely on its head, Inheritance will dazzle readers as they learn how to apply this compendium of groundbreaking genetic research in their daily lives and take control of their destiny in a manner their parents could only have dreamed of.
Inheritance in Contemporary America: The Social Dimensions of Giving across Generations (Gerontology)
by Jacqueline L. AngelWith the baby boom generation on the cusp of retirement, life expectancies on the rise, and the nation’s cultural makeup in flux, the United States is faced with social and policy quandaries that demand attention. How are elders to balance the competing claims of helping family members during their lifetime, saving for old age, and planning estates? What roles should the state, family, and individuals play in supporting people during later life? Are new familial gift-giving trends sustainable, and, if so, what effects might they have on future generations?Inheritance in Contemporary America tackles the complex legal, policy, and emotional issues that surround bequests and inheritances in an era of increasing longevity, broadening ethnicity, and unraveling social safety nets. Through empirical analyses, case studies, interviews, and anecdotes, Jacqueline L. Angel explains the historical nature of familial giving and how it is changing as the nation’s demographics shift. She explores the legal, personal, and policy complexities involved in passing wealth down through generations and provides a cross-disciplinary context for exploring the indelible effects that newly unfolding inheritance practices will have on various societal cohorts and the nation in general.From nuclear and extended families to the state and nongovernmental bodies, Angel’s engaging study explores how attitudes toward giving are evolving and confronts in stark terms the legacy that these shifts in attitude will leave. This book will be a vital tool for scholars and practitioners in gerontology, sociology, psychology, anthropology, economics, political science, and public policy.
Inherited Bleeding Disorders in Women
by Rezan A. Kadir Paula D. James Christine A. LeeThe essential guide for understanding and treating women with inherited bleeding disorders, revised and updated Now in its second edition, Inherited Bleeding Disorders in Women includes the most recent developments and research in the field. This important guide offers the most current information available for the effective management of these complex and difficult to diagnose disorders. Treating women with inherited bleeding disorders can be challenging and requires close collaboration among practitioners in different specialties. This important guide is written by a team of international experts who offer advice and practical suggestions for treating women with inherited bleeding disorders. Inherited Bleeding Disorders in Women comprehensively covers obstetric and gynecological issues for carriers of hemophilia, women with von Willebrand disease, rare bleeding disorders and inherited platelet disorders. This important resource: Offers an updated guide for hematologists, obstetricans and gynecologists and other clinicians treating women with inherited bleeding disorders Includes information for treating both common and rare bleeding disorders Contains the most recent developments and advances in the field for the treatment and management of inherited bleeding disorders in women Presents information from noted experts in the field Offers a multidisciplinary approach to the topic Written for hematologists, obstetricians and gynecologists and other clinicians working with women, Inherited Bleeding Disorders in Women has been fully revised and updated and continues to serve as a trusted guide for the management and treatment of women with inherited bleeding disorders.
Inherited Cancer Syndromes
by C. Neal EllisThe second edition of Inherited Cancer Syndromes incorporates new genetic markers data with the clinical utility and practicality of the first edition.
Inherited Disorders of the Thyroid System (Routledge Revivals)
by Geraldo Medeiros-Neto John B. StanburyFirst Published in 1994, Inherited Disorders of the Thyroid System presents a thorough and comprehensive study of the biology of varied thyroid disorders illustrated by numerous tables and figures. This monograph begins with the initial step in thyroid hormone production and concludes with the interaction of the thyroid hormones with their target cells. The authors have been involved in research in this field for many years and help to bring together, in a single text, the widely scattered literature relevant to the disorders of the thyroid system.
Inherited Metabolic Diseases: Research, Epidemiology and Statistics, Research, Epidemiology and Statistics
by Steve Hannigan Steve FieldInherited Metabolic Diseases are common enough for health, social service and education professionals to encounter them periodically, but rare enough for them to be poorly understood. They severely affect up to 1 in 10,000 people, and lead to a wide range of special needs in care and education. This guide provides specialist information on metabolic diseases for the non-specialist. In a concise, accessible and family-friendly format, each entry lists the names by which a condition is known, and explains the genetic causes of the disease, the physical effects, the patient's symptoms, and available treatments. Key diseases from all ten major groups of metabolic disorders are described, and all entries have been reviewed by Specialist Advisers. The work has been coordinated by the charity Climb, Children Living with Inherited Metabolic Diseases. This uniquely comprehensive source of information is a vital reference for hospital doctors including paediatricians, general practitioners, nurses and other health professionals, social service and education staff and managers, and the families and carers of children with the conditions.
Inherited Metabolic Diseases
by Georg F. Hoffmann Johannes Zschocke William L. NyhanThis book focuses on clinical presentations that may be caused by inherited metabolic diseases. Its symptom- and system-based approach will help clinicians with and without detailed knowledge of human biochemistry in all specialties to reach a correct diagnosis and institute the optimal treatment program. The book summarizes the central elements of inherited metabolic diseases and describes clearly how to carry out an efficient yet complete diagnostic work-up, thereby guiding the clinician from the presenting symptoms and signs through to effective initial management. After an introduction to the different disorders, the book explains when to consider an inborn metabolic error and which initial tests to order. Core aspects such as structured communication, guidelines, transition, pregnancy, maternal care and how to respond to various medical emergencies are covered. Therapeutic concepts such as dietary treatment are delineated and practical advice provided on the quite different treatment approaches required for individual diseases. An extensive section structured according to organ systems outlines the correct approach in the context of specific symptoms and signs. The value of each of the potential investigations is explained, with precise advice on the interpretation of results. The inclusion of algorithms, tables, lists, and charts facilitates rapid decision making and information retrieval, and the appendices include a helpful guide to differential diagnosis based on clinical and biochemical phenotypes. This new updated edition of Inherited Metabolic Diseases will be an invaluable aid for the busy clinician and an excellent quick reference for metabolic and genetic specialists.
Inherited Metabolic Diseases
by William L. Nyhan Johannes Zschocke Georg F. HoffmannThe explosion of insights in the field of metabolic disease has shed new light on diagnostic as well as treatment options. 'Inherited Metabolic Disease - A Clinical Approach' is written with a reader-friendly consistent structure. It helps the reader to find the information in an easily accessible and rapid way when needed. Starting with an overview of the major groups of metabolic disorders it includes algorithms with questions and answers as well as numerous graphs, metabolic pathways, and an expanded index. Clinical and diagnostic details with a system and symptom based are given to facilitate an efficient and yet complete diagnostic work-up of individual patients.
Inherited Neurological Disorders
by Zhi-Ying WuThis book provides up-to-date information on various inherited neurological disorders, presenting 40 cases of inherited neurological disorders with genetic diagnosis and/or pathological confirming. These disorders include cerebellar ataxia (SCA1, SCA2, SCA3, etc. ), epileptic attacks related disorders (MELAS, MERRF, TSC, etc. ), motor neuron related disorders (ALS, HSP, CMT, etc. ), movement disorders (PD, PKD, DRD, etc. ), ion channel diseases (hypokalemic periodic paralysis, normal potassium periodic paralysis), muscle diseases (DMD, FSHD, LSM, etc. ), and dementia and psychiatric disorders (HD, CADASIL, CARASIL, etc. ). With the format of case study, one type of diseases is discussed on each chapter, basically consisted of 5 sections. Section 1 focuses on the detailed clinical features, physical examination and hematological examination, while Section 2 addresses questions regarding diagnosis and differential diagnosis. Additional information such as imaging material and genetic/pathological results are provided in Section 3, followed by the final diagnosis in Section 4. Section 5 presents a systemic review for each specific disease. The book will benefit clinicians especially neurologists, medical students, researchers and healthcare professionals facing difficult cases, particularly those involving fundamental research and diagnostic methods.
Inherited Neuromuscular Diseases
by Vicente Felipo Carmen Espinós Francesc PalauThis book represents the state of the art of neuromuscular diseases as a whole, including muscular dystrophies, mitochondrial disorders, peripheral neuropathies, spinal muscular atrophy, motoneurone disease and Friedreich ataxia. It offers a current review of inherited neuromuscular diseases under different approaches: genetics, pathomechanisms, therapies and treatments. Many genes with neuromuscular disorders have been reported, confirming the wide genetic heterogeneity of most of diseases of the peripheral nervous system. Genetic analyses allow the unequivocal diagnosis of neonatal, paediatric and adult disease whose etiology has a genetic basis, thus providing a more accurate prediction of natural history and prognosis, and reproductive planning for the family, not only offering genetic counselling and prenatal diagnosis but also preimplantational genetic diagnosis. Moreover, for a number of them molecular and cell pathogenesis is suggesting new molecular targets and, more relevant, novel therapeutic approaches are currently developing to manage and treat these disorders including new drugs and gene and cellular therapies. This is a reference book for neurologists and researchers interested in genetics, cellular biology, pathomechanisms, therapies and treatments of neuropathies.
Inherited Retinal Disease
by Hyeong-Gon YuThis book presents the latest knowledge and expert guidance on all aspects of inherited retinal diseases, including molecular genetics, diagnosis, clinical features, general principles of treatment, novel treatment methods, and genetic counseling. Recent years have witnessed great advances in understanding of the genetic and cytological background of these diseases. Genetic analysis methods such as next generation sequencing have remarkably reduced the cost and time required for massive analysis of patients’ samples. Studies on gene therapy and stem cell therapy have been successfully carried out in animal models, and gene therapy is now available for Leber congenital amaurosis caused by RPE65 mutations. Against this background, Inherited Retinal Disease will be an invaluable up-to-date resource for ophthalmologists, medical students, and researchers in ocular inflammation. In addition to supplying essential information on each individual disorder, it features many interesting cases contributed by global leaders in the field as well as clinical photographs obtained with newer imaging techniques and numerous images of rare but clinically important diseases.
Inheriting Madness: Professionalization and Psychiatric Knowledge in Nineteenth Century France
by Ian Robert DowbigginHistorically, one of the recurring arguments in psychiatry has been that heredity is the root cause of mental illness. In Inheriting Madness, Ian Dowbiggin traces the rise in popularity of hereditarianism in France during the second half of the nineteenth century to illuminate the nature and evolution of psychiatry during this period. In Dowbiggin's mind, this fondness for hereditarianism stemmed from the need to reconcile two counteracting factors. On the one hand, psychiatrists were attempting to expand their power and privileges by excluding other groups from the treatment of the mentally ill. On the other hand, medicine's failure to effectively diagnose, cure, and understand the causes of madness made it extremely difficult for psychiatrists to justify such an expansion. These two factors, Dowbiggin argues, shaped the way psychiatrists thought about insanity, encouraging them to adopt hereditarian ideas, such as the degeneracy theory, to explain why psychiatry had failed to meet expectations. Hereditarian theories, in turn, provided evidence of the need for psychiatrists to assume more authority, resources, and cultural influence. Inheriting Madness is a forceful reminder that psychiatric notions are deeply rooted in the social, political, and cultural history of the profession itself. At a time when genetic interpretations of mental disease are again in vogue, Dowbiggin demonstrates that these views are far from unprecedented, and that in fact they share remarkable similarities with earlier theories. A familiarity with the history of the psychiatric profession compels the author to ask whether or not public faith in it is warranted.
The Inhibitor Index: A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads
by Daniel PurichMetabolic inhibitors and receptor antagonists are indispensable tools for the molecular life scientist. By blocking specific enzymes or receptor-mediated signal transduction cascades, they simplify the analysis of complex cellular processes especially when it is essential to demonstrate that a process of interest is functionally linked to a particular enzyme or receptor. From antibiotics to statins, modern medicine relies on the reliability and ease-of-use of enzyme- and receptor-directed inhibitors and antagonists.The Inhibitor Index is a comprehensive, curated compendium of over 7,800 enzyme inhibitors and receptor antagonists, including many toxins, poisons, and metabolic uncouplers.
Inhibitory Control and Drug Abuse Prevention
by Richard Milich Michael T. Bardo Diana H. FishbeinThe purpose of this book is to review our state of knowledge about the neurobehavioral and psychosocial processes involved in behavioral inhibitory processes and to provide an insight into how these basic research findings may be translated into the practice of drug abuse prevention interventions. Over the last decade, there has been a wealth of information indicating that substance use disorders do not simply reflect an exaggeration of reward seeking behavior, but that they also represent a dysfunction of behavioral inhibitory processes that are critical in exercising self-control. A number of studies have determined that individuals with substance use disorders have poor inhibitory control compared to non-abusing individuals. In addition, the fact that the adolescent period is often characterized by a lack of inhibitory control may be one important reason for the heightened vulnerability for the initiation of drug use during this time. Controlled experiments utilizing neuroscience techniques in laboratory animals or neuroimaging techniques in humans have revealed that individual differences in prefrontal cortical regions may underlie, at least in part, these differences in inhibitory control. Although a few excellent journal reviews have been published on the role of inhibitory deficits in drug abuse, there has been relatively little attention paid to the potential applications of this work for drug abuse prevention. The current book will provide both basic and applied researchers with an overview of this important health-relevant topic. Since translational research cuts across multiple disciplines and most readers are not familiar with all of these disciplines, the reading level will be geared to be accessible to graduate students, as well as to faculty and researchers in the field. The book will be organized around three general themes, encased within introductory and concluding chapters. The first theme will review basic neurobehavioral research findings on inhibition and drug abuse. Chapters in this theme will emphasize laboratory studies using human volunteers or laboratory animals that document the latest research implicating a relation between inhibition and drug abuse at both the neural and behavioral levels of analysis. The second theme will move the topic to at-risk populations that have impulse control problems, including children, adolescents and young adults. The third theme will concentrate on prevention science as it relates to inhibitory control. Chapters in this theme will be written by experts attempting to develop and improve prevention interventions by integrating evidence-based knowledge about inhibitory control processes. In all of the chapters, writers will be asked to speculate about innovative approaches that may be useful for the practice of prevention.
Inhibitory Synaptic Plasticity
by Arianna Maffei Melanie A. WoodinThis volume will explore the most recent findings on cellular mechanisms of inhibitory plasticity and its functional role in shaping neuronal circuits, their rewiring in response to experience, drug addiction and in neuropathology. Inhibitory Synaptic Plasticity will be of particular interest to neuroscientists and neurophysiologists.
Initial Guidance for an Update of the National Vaccine Plan: A Letter Report to the National Vaccine Program Office
by Institute of Medicine of the National AcademiesThis book is the Institute of Medicine's response to the first part of the statement of task asking for a review of the 1994 National Vaccine Plan. The Committee on the Review of Priorities in the National Vaccine Plan reviewed the goals, objectives, strategies, and anticipated outcomes presented in the plan; their findings are contained in this book. In the first section of the book, the committee examines what has changed in the broader social, policy, and economic context of vaccine development and immunization, and highlights several areas where noteworthy progress has been made, particularly by federal agencies. The committee acknowledges that progress in developing and delivering vaccines has benefited from essential contributions by other stakeholders, including researchers, manufacturers, state and local public health agencies, and health care providers. In the second section of the book, the committee uses what it learned from reviewing the 1994 plan and the process of preparing it to distill key elements. Based on these elements, the committee offers guidance to NVPO and its partners on developing the update to the national vaccine plan.
Initial Management of Acute Medical Patients: A Guide for Nurses and Healthcare Practitioners
by Ian Wood Michelle GarnerInitial Management of Acute Medical Patients is a clinically focused, practical and contemporary guide for assessing and managing patients with acute medical conditions. Suitable for all nurses and healthcare practitioners in medical assessment units and medical wards, as well as A&E staff, it uses a structured approach based on common presenting features and focuses on the first 24 hours of the patient's hospital stay. It draws on a wide range of supporting evidence and also provides sources for further reading. Key features: Written predominantly by nurses for nurses, this text is also suitable for a range of healthcare professionals, including paramedics and nurse practitioners, and anybody working in an acute care environment, including primary care assessment units, clinical decision units and intermediate care Designed as a quick reference text for use in clinical practice Extensively referenced throughout, thus increasing its appeal to practitioners at all stages of their careers and to those who are undertaking further study Devotes two entire chapters to assessing and meeting the acute care needs of vulnerable adults (i.e. older adults, those with mental health needs, and those with learning disabilities), and discussing best practice in dealing with sudden death Each chapter offers clear, concise and down-to-earth information based on a common presenting symptom and provides practical advice, supported by best evidence and the most up to date clinical guidelines Fully updated and extensively expanded to include recent guidelines and procedures