- Table View
- List View
An Introduction to Bioanalysis of Biopharmaceuticals (AAPS Advances in the Pharmaceutical Sciences Series #57)
by Seema KumarThe book provides a comprehensive review of the fundamental and practical aspects of bioanalytical support and the integral role it plays in the development of safe and efficacious biopharmaceutical drugs with speed and cost-effectiveness. The book focuses on a broad range of conventional and emerging biopharmaceutical modalities including monoclonal antibody-based therapeutics, gene therapy, cell therapy, peptides and oligonucleotides. The book starts with an introductory overview of bioanalysis showcasing the integral role it plays in understanding the drug disposition (pharmacokinetics/pharmacodynamics and immunogenicity) and the progression of bioanalytical strategy as the drug progresses through discovery and development stages of the program, taking into consideration the continually evolving regulatory landscape. The book further diversifies into individual biopharmaceutical modalities - monoclonal antibodies, antibody-drug conjugates, bispecifics, Fc-fusion proteins, gene therapies, cell therapies, peptides and oligonucleotides. The individual chapters focus on modality-specific bioanalytical assay strategies, critical reagents, assay formats, analytical platforms, associated bioanalytical challenges and mitigation strategies, industry best practices, and the latest understanding of regulatory guidance as applicable to the fast-growing biopharmaceutical landscape.
Introduction to Bioinformatics and Clinical Scientific Computing
by Paul S. GanneyThis textbook provides an introduction to computer science theory, informatics best practice, and the standards and legislation that apply to computing in a healthcare environment. It delivers an accessible discussion of databases (construction, interrogation and maintenance); networking (design and low-level application); programming (best practice rather than the specifics of any one language – design, maintenance, safety). It can be used to accompany the NHS Modernising Scientific Careers syllabus. It is also targeted towards those creating software rather than those using it, particularly computer scientists working in healthcare, specifically those in or close to the Physical Sciences, including radiotherapy, nuclear medicine, and equipment management and those working with genomics and health informatics.
Introduction to Bioinformatics in Microbiology (Learning Materials in Biosciences)
by Henrik ChristensenThis textbook introduces to the basic concepts of bioinformatics and enhances students’ skills in using software and tools relevant for investigations in microbiology. The most relevant methods to analyze data are shown and readers are introduced on how to draw valid conclusions based on the results obtained. Software and servers which are free to use on the internet are presented and more advanced stand-alone programs are suggested as a second option. Exercises and training quizzes are provided at the end of each chapter to facilitate learning. The book targets Ph. D. students and advanced undergraduates in microbiology, biotechnology, and (veterinary) medicine with little to basic knowledge in bioinformatics.
Introduction to Bioinformatics in Microbiology (Learning Materials in Biosciences)
by Henrik ChristensenThis updated and extended second edition of the textbook introduces the basic concepts of bioinformatics and enhances students' skills in the use of software and tools relevant to microbiology research. It discusses the most relevant methods for analysing data and teaches readers how to draw valid conclusions from the observations obtained. Free software and servers available on the Internet are presented in an updated version of 2023 and more advanced stand-alone software is proposed as a second option. In addition, new tools for microbial genome analysis and new flowcharts that complement the didactic elements have been added. Exercises and training questionnaires are included at the end of each chapter to facilitate learning. The book is aimed at Ph.D. students and advanced undergraduate students in microbiology, biotechnology, and (veterinary) medicine with little or basic knowledge of bioinformatics.
Introduction to Biologic and Biosimilar Product Development and Analysis (AAPS Introductions in the Pharmaceutical Sciences)
by Karen M. NagelThe purpose of this book is to give a concise introduction to development and analysis of pharmaceutical biologics for those in the pharmaceutical industry who are switching focus from small molecules to biologics processing, analysis, and delivery. In order to maintain a limited focus, Introduction to Biologic and Biosimilar Product Development and Analysis, will deal only with peptides, proteins and monoclonal antibodies.
Introduction to Biological Imaging
by Manfred AuerIntroduction to Biological Imaging Discover what biological imaging is able to accomplish in this up-to-date textbook One of the fundamental goals of biology is to understand how living organisms establish and maintain their spatiotemporal organization of the biochemical, cell biological and developmental biology processes that sustain life. Biological systems are inherently complex with a large number of components needed to sustain cellular function. In order to understand any complex system, one must determine its composition by identifying the components it is made of, how each of these components function and carry out their specific task, and how they interact with one another to function together. To grasp the link of such changes to physiological cell and tissue function and/or pathogenesis/disease progression, we need to understand how modifications alter macromolecular function, macromolecular interactions, and/or spatiotemporal distribution and overall supramolecular structural organization. Biological imaging holds the key to understanding spatiotemporal organization, and will thus be increasingly important for the next generations of biological and biochemical researchers. Introduction to Biological Imaging provides the first comprehensive textbook surveying this subject. It elucidates the fundamental principles underlying the capture and production of bioimages, the requirements of image analysis and interpretation, and some key problems and solutions in bioimaging. It includes everything experimental biologists need to incorporate appropriate bioimaging solutions into their work. Introduction to Biological Imaging readers will also find: Coverage of all major types of biological imaging, including medical imaging, cellular imaging, macromolecular imaging, and more Advice on preparing samples for various imaging methods Specific examples in each chapter connecting bioimaging process to the production of real experimental data Introduction to Biological Imaging is a valuable introduction for undergraduate or graduate students in courses relating to bioimaging, as well as scientists and researchers in the biological and medical fields who want a one-stop reference for the full range of imaging techniques.
Introduction to Biomaterials
by C. Mauli Agrawal Joo L. Ong Mark R. Appleford Gopinath Mani C. Mauli Agrawal Joo L. Ong Mark R. ApplefordThis succinct textbook gives students the perfect introduction to the world of biomaterials, linking the fundamental properties of metals, polymers, ceramics and natural biomaterials to the unique advantages and limitations surrounding their biomedical applications. Clinical concerns such as sterilization, surface modification, cell-biomaterial interactions, drug delivery systems, and tissue engineering are discussed in detail, giving students practical insight into the real-world challenges associated with biomaterials engineering; key definitions, equations and concepts are concisely summarised alongside the text, allowing students to quickly and easily identify the most important information; and bringing together elements from across the book, the final chapter discusses modern commercial implants, challenging students to consider future industrial possibilities. Concise enough to be taught in a single semester, and requiring only a basic understanding of biology, this balanced and accessible textbook is the ideal introduction to biomaterials for students of engineering, materials science and medicine. <P><P><i>Advisory: Bookshare has learned that this book offers only partial accessibility. We have kept it in the collection because it is useful for some of our members. Benetech is actively working on projects to improve accessibility issues such as these.</i>
An Introduction to Biomechanics: Solids and Fluids, Analysis and Design
by Jay D. Humphrey Sherry L. O'RourkeThis book covers the fundamentals of biomechanics. Topics include bio solids, biofluids, stress, balance and equilibrium. Students are encouraged to contextualize principles and exercises within a "big picture" of biomechanics. This is an ideal book for undergraduate students with interests in biomedical engineering.
Introduction to Biomedical Engineering Technology
by Laurence J. StreetThis new edition provides major revisions to a text that is suitable for the introduction to biomedical engineering technology course offered in a number of technical institutes and colleges in Canada and the US. Each chapter has been thoroughly updated with new photos and illustrations which depict the most modern equipment available in medical technology. This third edition includes new problem sets and examples, detailed block diagrams and schematics and new chapters on device technologies and information technology.
Introduction to Biomedical Engineering Technology, 4th Edition: Health Technology Management
by Laurence J. StreetThis updated fourth edition provides current information on devices and is divided into diagnostic and treatment sections. Devices are described with the theory of operation and relevant anatomical and physiological considerations. Aspects of BMET work including test equipment, standards, and information technology are also discussed. The text covers a wide variety of diagnostic and treatment devices currently used in hospitals that students will likely encounter in their career. Principles of operation and examples of use are provided. This book is unique in that it is written by an experienced biomed tech with 30 years’ experience in hospitals rather than by engineers with little frontline experience. It is also unique in that it provides ancillary materials on the web and is the only guide divided into diagnostic and treatment device sections. This new edition also includes two new chapters on computers, information technology, and networking as well as health technology management. From the previous edition: "The book presents a comfortable balance between clinical applications, basic technical information, and various pictures of medical technologies one will encounter in the field. Additionally, related anatomy and physiology principles and essential technical terms are a nice complement to the technologies presented. The everyday duties and responsibilities of a biomed are captured by the various ‘true-to-life’ scenarios introduced throughout the book." —Joey Jones, Madisonville Community College, Kentucky, USA This book is intended for students in biomedical engineering technology and healthcare technology management (BMET/HTM) programs as well as biomedical engineering students. Field service representatives, medical device designers, and medical device sales representatives will also find it useful.
Introduction to Biomedical Imaging: Physics, Engineering And Clinical Applications (IEEE Press Series on Biomedical Engineering)
by Andrew WebbIntroduction to BiomedicalImaging A state-of-the-art exploration of the foundations and latest developments in biomedical imaging technology In the newly revised second edition of Introduction to Biomedical Imaging, distinguished researcher Dr. Andrew Webb delivers a comprehensive description of the fundamentals and applications of the most important current medical imaging techniques: X-ray and computed tomography, nuclear medicine, ultrasound, magnetic resonance imaging, and various optical-based methods. Each chapter explains the physical principles, instrument design, data acquisition, image reconstruction, and clinical applications of its respective modality. This latest edition incorporates descriptions of recent developments in photon counting CT, total body PET, superresolution-based ultrasound, phased-array MRI technology, optical coherence tomography, and iterative and model-based image reconstruction techniques. The final chapter discusses the increasing role of artificial intelligence/deep learning in biomedical imaging. The text also includes a thorough introduction to general image characteristics, including discussions of signal-to-noise and contrast-to-noise. Perfect for graduate and senior undergraduate students of biomedical engineering, Introduction to Biomedical Imaging, 2nd Edition will also earn a place in the libraries of medical imaging professionals with an interest in medical imaging techniques.
Introduction to Biomedical Imaging
by Andrew G. WebbAn integrated, comprehensive survey of biomedical imaging modalities An important component of the recent expansion in bioengineering is the area of biomedical imaging. This book provides in-depth coverage of the field of biomedical imaging, with particular attention to an engineering viewpoint. Suitable as both a professional reference and as a text for a one-semester course for biomedical engineers or medical technology students, Introduction to Biomedical Imaging covers the fundamentals and applications of four primary medical imaging techniques: magnetic resonance imaging, ultrasound, nuclear medicine, and X-ray/computed tomography. Taking an accessible approach that includes any necessary mathematics and transform methods, this book provides rigorous discussions of: The physical principles, instrumental design, data acquisition strategies, image reconstruction techniques, and clinical applications of each modality Recent developments such as multi-slice spiral computed tomography, harmonic and sub-harmonic ultrasonic imaging, multi-slice PET scanning, and functional magnetic resonance imaging General image characteristics such as spatial resolution and signal-to-noise, common to all of the imaging modalities
Introduction to Biomedical Instrumentation
by Barbara ChristeThis fully updated second edition provides readers with all they need to understand the use of medical technology in patient care. Incorporating the most recent changes in healthcare, regulations, Standards, and technology, coverage is expanded to include new chapters on device testing, with a particular emphasis on safety inspections, and the interface of medical technology with the electronic medical record. A wide variety of medical instrumentation is discussed, focusing on device types and classifications, and including individual manufacturers as examples. It is designed for readers with a fundamental understanding of anatomy, physiology and medical terminology, as well as electronic concepts such as voltage, current, resistance, impedance, analog and digital signals, and sensors. Additional documents and solutions to end-of-chapter questions accompany the book online, providing biomedical engineering technicians with the resources and tools they need to become knowledgeable and effective members of the patient care team.
Introduction to Bionanotechnology
by Young-Chul Lee Ju-Young MoonThis is a comprehensive overview of bionanotechnology to students in nanotechnology, biotechnology, bionanotechnology, related fields such as biology, chemistry, physics, and materials science and also everyone who is interested in this research area. It describes the definition of bionanomaterials, how they can be synthesized, characterized and applied in different fields. The current status and future of bionanotechnology, as well as its advantages and limitations, are comprehensively discussed throughout the book. This is an entry-level book which is easy for readers to understand its contents. In this book, we tried to identify the definition of bionanotechnology. Briefly, Bionanotechnology is the emerging research field that comes from the intersection of nanotechnology and biotechnology. Nanotechnology is referring to the design, development, and application of materials which at least one dimension at nanometer scale meanwhile biotechnology is developed based on knowledge about living systems and organisms to create or improve different products. The association of nanotechnology and biotechnology pave a way to develop a hybrid technology with unique features. Thus, this novel technology will be used to improve our living standard in different aspects from developing new medicine, food, and functional cosmetics, introducing new methods to analyze and treat cancer to protect environmental problems.
Introduction to Bioorganic Chemistry and Chemical Biology
by David Van Vranken Gregory A. WeissIntroduction to Bioorganic Chemistry and Chemical Biology is the first textbook to blend modern tools of organic chemistry with concepts of biology, physiology, and medicine. With a focus on human cell biology and a problems-driven approach, the text explains the combinatorial architecture of biooligomers (genes, DNA, RNA, proteins, glycans, lipids, and terpenes) as the molecular engine for life. Accentuated by rich illustrations andmechanistic arrow pushing, organic chemistry is used to illuminate the central dogma of molecular biology.Introduction to Bioorganic Chemistry and Chemical Biology is appropriate for advanced undergraduate and graduate students in chemistry and molecular biology, as well as those going into medicine and pharmaceutical science.Please note that Garland Science flashcards are no longer available for this text. However, the solutions can be obtained through our Support Material Hub link below, but should only be requested by instructors who have adopted the book on their course.
Introduction to Biosocial Medicine: The Social, Psychological, and Biological Determinants of Human Behavior and Well-Being
by Donald A. Barr<p>While 40 percent of premature deaths in the United States can be attributed to such dangerous behaviors as smoking, overeating, inactivity, and drug or alcohol use, medical education has generally failed to address how these behaviors are influenced by social forces. This new textbook from Dr. Donald A. Barr was designed in response to the growing recognition that physicians need to understand the biosocial sciences behind human behavior in order to be effective practitioners. Introduction to Biosocial Medicine explains the determinants of human behavior and the overwhelming impact of behavior on health. <p>Drawing on both recent and historical research, the book combines the study of the biology of humans with the social and psychological aspects of human behavior. Dr. Barr, a sociologist as well as physician, illustrates how the biology of neurons, the intricacies of the human mind, and the power of broad social forces all influence individual perceptions and responses. Addressing the enormous potential of interventions from medical and public health professionals to alter these patterns of human behavior over time, Introduction to Biosocial Medicine brings necessary depth and perspective to medical training and education.</p>
Introduction to Biosocial Medicine: The Social, Psychological, and Biological Determinants of Human Behavior and Well-Being
by Donald A. BarrUnderstanding human behavior is essential if medical students and doctors are to provide more effective health care.While 40 percent of premature deaths in the United States can be attributed to such dangerous behaviors as smoking, overeating, inactivity, and drug or alcohol use, medical education has generally failed to address how these behaviors are influenced by social forces. This new textbook from Dr. Donald A. Barr was designed in response to the growing recognition that physicians need to understand the biosocial sciences behind human behavior in order to be effective practitioners. Introduction to Biosocial Medicine explains the determinants of human behavior and the overwhelming impact of behavior on health. Drawing on both recent and historical research, the book combines the study of the biology of humans with the social and psychological aspects of human behavior. Dr. Barr, a sociologist as well as physician, illustrates how the biology of neurons, the intricacies of the human mind, and the power of broad social forces all influence individual perceptions and responses. Addressing the enormous potential of interventions from medical and public health professionals to alter these patterns of human behavior over time, Introduction to Biosocial Medicine brings necessary depth and perspective to medical training and education.
Introduction to Biostatistical Applications in Health Research with Microsoft Office Excel
by Robert P. HirschA practical and methodological approach to the statistical logic of biostatistics in the field of health research Focusing on a basic understanding of the methods and analyses in health research, Introduction to Biostatistical Applications in Health Research with Microsoft® Office Excel® provides statistical concepts for interpreting results using Excel. The book emphasizes the application of methods and presents the most common methodological procedures in health research, which includes multiple regression, ANOVA, ANCOVA, logistic regression, Cox regression, stratified analysis, life table analysis, and nonparametric parallels. The book is constructed around a flowchart that outlines the appropriate circumstances for selecting a method to analyze a specific set of data. Beginning with an introduction to the foundational methods of statistical logic before moving on to more complex methods, Introduction to Biostatistical Applications in Health Research with Microsoft® Office Excel® also includes: Detailed discussions of how knowledge and skills in health research have been integrated with biostatistical methods Numerous examples with clear explanations that use mostly real-world health research data in order to provide a better understanding of the practical applications Implements Excel graphic representations throughout to help readers evaluate and analyze individual results An appendix with basic information on how to use Excel A companion website with additional Excel files, data sets, and homework problems as well as an Instructor's Solutions Manual Introduction to Biostatistical Applications in Health Research with Microsoft® Office Excel® is an excellent textbook for upper-undergraduate and graduate-level courses in biostatistics and public health. In addition, the book is an appropriate reference for both health researchers and professionals.
Introduction to Biostatistical Applications in Health Research with Microsoft Office Excel and R
by Robert P. HirschThe second edition of Introduction to Biostatistical Applications in Health Research delivers a thorough examination of the basic techniques and most commonly used statistical methods in health research. Retaining much of what was popular with the well-received first edition, the thoroughly revised second edition includes a new chapter on testing assumptions and how to evaluate whether those assumptions are satisfied and what to do if they are not. The newest edition contains brand-new code examples for using the popular computer language R to perform the statistical analyses described in the chapters within. You’ll learn how to use Excel to generate datasets for R, which can then be used to conduct statistical calculations on your data. The book also includes a companion website with a new version of BAHR add-in programs for Excel. This new version contains new programs for nonparametric analyses, Student-Newman-Keuls tests, and stratified analyses. Readers will also benefit from coverage of topics like: Extensive discussions of basic and foundational concepts in statistical methods, including Bayes’ Theorem, populations, and samples A treatment of univariable analysis, covering topics like continuous dependent variables and ordinal dependent variables An examination of bivariable analysis, including regression analysis and correlation analysis An analysis of multivariate calculations in statistics and how testing assumptions, like assuming Gaussian distributions or equal variances, affect statistical outcomes Perfect for health researchers of all kinds, Introduction to Biostatistical Applications in Health Research also belongs on the bookshelves of anyone who wishes to better understand health research literature. Even those without a great deal of mathematical background will benefit greatly from this text.
Introduction to Biotech Entrepreneurship: A European Perspective
by Florentina Matei Daniela ZirraPrimarily intended for biotechnology graduates, this handbook provides an overview of the requirements, opportunities and drawbacks of Biotech Entrepreneurship, while also presenting valuable training materials tailored to the industrial and market reality in the European Biotech Business. Potential investors and business consultants will find essential information on the benefits and potential risks involved in supporting biotech businesses. Further, the book addresses a broad range of Biotechnology fields, e.g. food biotech, industrial biotech, bioinformatics, animal and human health. Readers will learn the essentials of creating innovations, founding a biotech start-up, business management strategies, and European funding sources. In addition, the book discusses topics such as intellectual property management and innovation transfer.The book offers a comparative analysis of different countries’ perspectives and reviews the status quo in Western and Eastern European regions, also in comparison with other leading biotech countries such as the USA and Canada. A long list of potentially profitable biotech start-up ideas and a collection of success stories involving European companies are also included.The book is based on the Erasmus+ Strategic Partnership project “Supporting biotechnology students oriented towards an entrepreneurial path” (www.supbioent.usamv.ro), which involved the collaboration of Life Sciences and Economics departments at higher education institutions throughout Western and Eastern Europe.
An Introduction to Brain and Behavior
by Bryan Kolb Ian Q. Whishaw G. Campbell TeskeyFrom authors Bryan Kolb and Ian Whishaw, and new coauthor G. Campbell Teskey, An Introduction to Brain and Behavior offers a unique inquiry-based introduction to behavioral neuroscience, with each chapter focusing on a central question (i. e. , "How Does the Nervous System Function?"). It also incorporates a distinctive clinical perspective, with examples showing students what happens when common neuronal processes malfunction. Now this acclaimed book returns in a thoroughly up-to-date new edition. Founders of a prestigious neuroscience institute at the University of Lethbridge in Alberta, Canada, Kolb and Whishaw are renowned as both active scientists and teachers. G. Campbell Teskey of the University of Calgary, also brings to the book a wealth of experience as a researcher and educator. Together, they are the ideal author team for guiding students from a basic understanding the biology of behavior to the very frontiers of some of the most exciting and impactful research being conducted today. The new edition also has its own dedicated version of Worth Publishers' breakthrough online course space, LaunchPad, giving it the most robust media component of any textbook for the course.
An Introduction to Brain and Behavior
by Kolb Whishaw TeskeyFrom authors Bryan Kolb and Ian Whishaw, and new coauthor G. Campbell Teskey, An Introduction to Brain and Behavior offers a unique inquiry-based introduction to behavioral neuroscience, with each chapter focusing on a central question (i.e., "How Does the Nervous System Function?"). It also incorporates a distinctive clinical perspective, with examples showing students what happens when common neuronal processes malfunction. Now this acclaimed book returns in a thoroughly up-to-date new edition. <P><P> Founders of a prestigious neuroscience institute at the University of Lethbridge in Alberta, Canada, Kolb and Whishaw are renowned as both active scientists and teachers. G. Campbell Teskey of the University of Calgary, also brings to the book a wealth of experience as a researcher and educator. Together, they are the ideal author team for guiding students from a basic understanding the biology of behavior to the very frontiers of some of the most exciting and impactful research being conducted today. <P><P><i>Advisory: Bookshare has learned that this book offers only partial accessibility. We have kept it in the collection because it is useful for some of our members. Benetech is actively working on projects to improve accessibility issues such as these.</i>
Introduction to Bronchoscopy
by Armin Ernst Herth Felix J. F.Bronchoscopic procedures are commonly performed for diagnosis of respiratory disorders and therapeutic airway treatment and management. A thorough understanding of procedural and technical fundamentals is critical for improving yield and safety, but they are not featured in procedural reviews for advanced endoscopists. In this book those critical cornerstones of performing bronchoscopy are discussed and explained in detail. Following the successful structure of the first edition, the fully updated content provides detailed reviews of procedural fundamentals including endobronchial ultrasound. Equipment components are described and maintenance is discussed. All chapters include advice on procedural quality improvement. Regulatory requirements, bronchoscopy procedure unit design and management principles are also addressed. This text will be beneficial to a wide range of practitioners including trainees and specialists in pulmonary and all critical care fields, surgeons, anaesthesiologists and respiratory therapists.
Introduction to Cancer Biology
by Robin HeskethThis concise overview of the fundamental concepts of cancer biology is ideal for those with little or no background in the field. A summary of global cancer patterns introduces students to the general principles of how cancers arise and the risk factors involved. By focusing on fundamental examples of the signalling pathways within cells, the functional effects of DNA damage are explained. Later chapters then build on this foundation to provide a comprehensive summary of the major signalling pathways that affect tumour development. Current therapeutic strategies are reviewed, along with a discussion of methods for tumour detection and biomarker identification. Finally, the impact of whole genome sequencing is discussed, bringing students up to date with key recent developments in the field. From basic principles to insights into cutting-edge research, this book will enable the reader to move into the cancer field with confidence.
Introduction to Cardiopulmonary Exercise Testing
by Robb W. Glenny H. Thomas Robertson Andrew M. LuksCardiopulmonary exercise testing is an important diagnostic test in pulmonary medicine and cardiology. Capable of providing significantly more information about an individual's exercise capacity than standard exercise treadmill or 6-minute walk tests, the test is used for a variety of purposes including evaluating patients with unexplained exercise limitation or dyspnea on exertion, monitoring disease progression or response to treatment, determining fitness to undergo various surgical procedures and monitoring the effects of training in highly fit athletes. Introduction to Cardiopulmonary Exercise Testing is a unique new text that is ideal for trainees. It is presented in a clear, concise and easy-to-follow manner and is capable of being read in a much shorter time than the available texts on this topic. Chapters describe the basic physiologic responses observed during sustained exercise and explain how to perform and interpret these studies. The utility of the resource is further enhanced by several sections of actual patient cases, which provide opportunities to begin developing test interpretation skills. Given the widespread use of cardiopulmonary exercise testing in clinical practice, trainees in pulmonary and critical care medicine, cardiology, sports medicine, exercise physiology, and occasionally internal medicine, will find Introduction to Cardiopulmonary Exercise Testing to be an essential and one of a kind reference.