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Issues in Returning Individual Results from Genome Research Using Population-Based Banked Specimens, with a Focus on the National Health and Nutrition Examination Survey: A Workshop Summary
by Kevin KinsellaPopulation surveys traditionally collect information from respondents about their circumstances, behaviors, attitudes, and other characteristics. In recent years, many surveys have been collecting not only questionnaire answers, but also biologic specimens such as blood samples, saliva, and buccal swabs, from which a respondent's DNA can be ascertained along with other biomarkers (e. g. , the level of a certain protein in the blood). The National Health and Nutrition Examination Survey (NHANES), sponsored by the National Center for Health Statistics (NCHS), has been collecting and storing genetic specimens since 1991, and other surveys, such as the Health and Retirement Study (HRS) funded by the National Institute on Aging, have followed suit. In order to give their informed consent to participate in a survey, respondents need to know the disposition and use of their data. Will their data be used for one research project and then destroyed, or will they be archived for secondary use? Sponsors of repeated cross-sectional surveys, such as NHANES, and of longitudinal surveys that follow panels of individuals over time, such as HRS, generally want to retain data for a wide range of secondary uses, many of which are not explicitly foreseen at the time of data collection. They typically inform respondents that their data will be stored in a secure manner and may be provided to researchers with suitable protections against individual identification. The addition of biologic specimens to a survey adds complications for storing, protecting, and providing access to such data and measurements made from them. There are also questions of whether, when, and for which biologic measurements the results should be reported back to individual respondents. Recently, the cost of full genomic sequencing has plummeted, and research findings are beginning to accumulate that bear up under replication and that potentially have clinical implications for a respondent. For example, knowing that one possesses a certain gene or gene sequence might suggest that one should seek a certain kind of treatment or genetic counseling or inform one's blood relatives. Biomedical research studies, in which participants are asked to donate tissues for genetic studies and are usually told that they will not be contacted with any results, are increasingly confronting the issue of when and which DNA results to return to participants. Issues in Returning Individual Results from Genome Research Using Population-Based Banked Specimens, with a Focus on the National Health and Nutrition Examination Survey is the summary of a workshop convened in February 2013 by the Committee on National Statistics in the Division of Behavioral and Social Sciences and Education of the National Research Council. This report considers how population surveys, in particular NHANES, should implement the reporting of results from genomic research using stored specimens and address informed consent for future data collection as well as for the use of banked specimens covered by prior informed consent agreements. The report will be of interest to survey organizations that include or contemplate including the collection of biologic specimens in population surveys for storing for genetic research. The issues involved are important for advancing social, behavioral, and biomedical knowledge while appropriately respecting and protecting individual survey respondents.
Issues in School Violence Research
by Rusell Skiba Gale Morrison Michael Furlong Dewey Gene CornellExplore the most effective methods of studying school violence!School violence and safety research will move forward and make unique scientific contributions only if it develops a core literature that critically examines its measurements, methods, and data analysis techniques. Issues in School Violence Research is the first book to expose the limitations of previous research, to critically examine methodological and measurement practices, and to provide guidelines to enhance future school violence research. Early literature focused on school violence as a social problem, not as an integrated area of legitimate scientific research. It is time to move beyond the social problem era of school violence to begin critically assessing its common research practices.Until recently, there has been such a rush to gather information about school violence that the methods used have hardly been questioned. The editors of this book are some of the first to raise questions about how the field conducts its research, especially with regard to self-reports among students. Issues in School Violence Research addresses significant measurement and methodological issues in school violence research. The contributors have been conducting school research for more than 15 years. To enhance your understanding of the practices used-past and proposed-numerous tables are included.In Issues in School Violence Research, you&’ll find information about: school-level warning signs of safety problems weapon possession using office referral records in school violence research identification of bullies and victims data quality issues in student risk behavior surveys extreme response bias patterns for youth risk behavior surveys the structure of student perceptions of school safety and much more!Issues in School Violence Research is an important resource for anyone, from professors to policymakers. It is also appropriate as a textbook for research methodology courses. It is only through objective analysis that school violence research can develop new insights. This book presents topics that should stimulate new and better inquiry into the climate within which school violence occurs.
Issues in the Political Economy of Health Care (Routledge Library Editions: Health, Disease and Society #25)
by John B. McKinlayOriginally published in 1984, this book attempted to fill a gap by providing a broad-ranging structural analysis of the health care sector and the political and economic forces which influence its shape and contents, both in the western world and developing countries. The contributors examine the relationships of capitalism to health care, in terms of its influence on the physical environment, the incidence of social diseases and the prevailing (20th Century) view of what constitutes health itself; and in terms of the consequences of the new medical industrial complex it has created, such as the declining provision of health care for the poor and disadvantaged and the growing power of the pharmaceutical industry.
Issues in Transnational Policing
by J. W. E. SheptyckiGlobalisation, the wired planet, the global village, these are a few of the terms associated with the social and political changes that are said to describe the world at the beginning of the new millennium. One of the most important institutions of the social ordering has been that of policing, but very little has been written on how the practices of social control are affected by the processes of transnationalisation. This book brings together contributions by experts on policing that focus on some of the newly emergent policing issues connected with these changes:*the global private security industry*cross national networking between police*the establishment of an international criminal court*money laundering *policing cyberspace*the drug warIssues in Transnational Policing crosses the boundaries between criminology, international relations and international law to provide a thought-provoking picture of the complex issues surrounding the politics of policing in the future.
Issues on Health and Healthcare in India
by Utpal Kumar De Manoranjan Pal Premananda BharatiThis book addresses health and healthcare issues in India with a special focus on the Northeast region. Pursuing a multidisciplinary approach, it highlights key issues in health and healthcare and outlines the actions needed to achieve the desired results in these areas as laid out in the UN Millennium Development Goals. In addition to introducing some new questions on health and healthcare development, it presents cross-country analyses, and examines the convergence of healthcare across Indian states, as well as mortality and morbidity in the Northeast. The book also explores the regional complexities involved in the discussion of these topics. It presents a number of specific techniques, such as two-level logistic regression, analysis of mental health, probabilistic and predictive analysis of nutritional deficit, and generalized linear mixed models, that can be used to analyze mortality and morbidity and factors affecting out-of-pocket expenses in the healthcare context. Lastly, it presents concrete case studies substantiating the theoretical models discussed. As such, the book offers a valuable resource for health researchers, professionals and policymakers alike.
It All Depends on the Dose: Poisons and Medicines in European History (The History of Medicine in Context)
by Ole Peter Grell Andrew Cunningham Jon ArrizabalagaThis is the first volume to take a broad historical sweep of the close relation between medicines and poisons in the Western tradition, and their interconnectedness. They are like two ends of a spectrum, for the same natural material can be medicine or poison, depending on the dose, and poisons can be transformed into medicines, while medicines can turn out to be poisons. The book looks at important moments in the history of the relationship between poisons and medicines in European history, from Roman times, with the Greek physician Galen, through the Renaissance and the maverick physician Paracelsus, to the present, when poisons are actively being turned into beneficial medicines.
IT-gestütztes Prozessmanagement im Gesundheitswesen: Methoden und Werkzeuge für Studierende und Praktiker
by Andreas GadatschSteigender Kostendruck und der Zwang zur Verbesserung der Wirtschaftlichkeit sind für Mitarbeiter im Gesundheitswesen Realität geworden. Viele Einrichtungen müssen ihre Arbeitsabläufe optimieren und gleichzeitig die Qualität ihrer Leistungen verbessern. Das Buch erläutert Grundlagen und ausgewählte Methoden des Prozessmanagements, die in Einrichtungen des Gesundheitswesens (Krankenhäuser, Krankenkassen und Krankenversicherungen) eingesetzt werden können. Der fachliche Schwerpunkt liegt auf der abteilungsübergreifenden Dokumentation, Analyse und Optimierung von Prozessen im Gesundheitswesen mit dem Ziel, die Transparenz zu erhöhen und die Effektivität und Effizienz zu steigern. Anhand von Fallbeispielen wird der Einsatz moderner Informations- und Kommunikationstechnologie als Instrument für die Prozessverbesserung dargestellt. Zahlreiche Wiederholungsfragen und Übungen machen das Werk zu einem Lern- und Arbeitsbuch, nicht nur für Studierende, sondern auch für erfahrene Praktiker im Gesundheitswesen.
It Happened in Paris... (A Valentine to Remember #722)
by Robin GiannaWhat started with a kiss... Avery Girard might have sworn off men, but she can't help but get swept away by the beauty, magic and romance of Valentine's Day in Paris...especially when she ends up spending it with totally irresistible Dr. Jack Dunbar. One little fling can't hurt, right? ...could end with forever! Wrong! After an afternoon of passion, Avery discovers that Jack is actually the cardiologist she is meant to be assessing! Even more worrying, when it comes to Jack, she's not only dangerously close to losing her professional cool...she's close to losing her heart.
It Happened in Vegas
by Amy RuttanThe hero she never forgot... Keeping out of the spotlight isn't easy for senator's daughter Dr. Jennifer Mills...especially after being jilted at the altar by her ex-fiancé! Arriving in Las Vegas, she's just hoping to blend in... But then she meets ER surgeon Nick Rousseau-the same man she spent an unforgettable night with three years earlier! Now returned from Afghanistan, ex-army medic Nick is struggling to come to terms with his time on the front line. Rekindling his romance with Jennifer reminds this brooding doctor that some things in life are still worth fighting for...
It Happened One Night Shift
by Amy AndrewsA stolen kiss in the ER Five years ago brooding ex-military medic Gareth Stapleton lost his beloved wife to breast cancer. Since then he's kept his distance from everything and everyone. Until Dr. Billie Ashworth-Keyes waltzes into his life and turns it upside down... Gareth is intrigued by the vivacious ER doc, but he knows she's off-limits. Then, one night shift, Gareth finds himself locked in the hottest kiss of his life! Suddenly he realizes that Billie is exactly what he needs to make his days-and nights-a lot more meaningful!
It Started at Christmas . . .
by Janice LynnAll she wants for Christmas is…him! This Christmas Dr. McKenzie Sanders knows exactly what she wants in her stocking her gorgeous colleague Lance Spencer. He&’s a sexy, brilliant, caring doctor and, best of all, he&’s just as averse to walking down the aisle as she is! They agree to indulge in a sizzling fling that will absolutely not end in wedded bliss. But even the best laid plans can go awry… Will risking their hearts lead to wedding bells?
It Started with a Winter Kiss
by Tina BeckettVoted most likely to marry…Will they finally have the chance?Dr. Dexter Chamblisse always has a plan. He just hadn’t planned on an ER reunion with his high school sweetheart, Maura! She may work in his hospital, but Dex has tried to keep his distance. He can’t bear to be reminded of the tragic accident that tore them apart. But it’s getting harder to ignore the sparks still flying between them… Could this be their second-chance Christmas?From Harlequin Medical: Life and love in the world of modern medicine.
It Takes a Worried Man: A Memoir
by Brendan HalpinThis book is a horror story and a comedy, but, most of all, it is a love story written when the author's wife was diagnosed with breast cancer. It is the story of what happens to a man who fears that his best friend might leave him forever.
It Takes a Worried Man: A Memoir
by Brendan HalpinHilarious and heartbreaking, profane and profound, It Takes a Worried Man is the true story of a young husband and father whose life is changed forever by his wife's breast cancer diagnosis. Following Brendan Halpin's cranky, irreverent and lustful thoughts through the diagnosis and treatment of his wife, Kirsten, It Takes a Worried Man is an unflinching and raw look at how cancer transforms a family. It's also the funniest book about cancer you'll ever read.
The Italian Boy: A Tale of Murder and Body-snatching in 1830s London
by Sarah WiseA thrilling history of England's great metropolis at a point of great change, told through the story of a young vagrant murdered by "resurrection men"Before his murder in 1831, the "Italian boy" was one of thousands of orphans on the streets of London, moving among the livestock, hawkers, and con men, begging for pennies. When his body was sold to a London medical college, the suppliers were arrested for murder. Their high-profile trial would unveil London's furtive trade in human corpses carried out by body-snatchers--or "resurrection men"--who killed to satisfy the first rule of the cadaver market: the fresher the body, the higher the price. Historian Sarah Wise reconstructs not only the boy's murder but the chaos and squalor of London that swallowed the fourteen-year-old vagrant long before his corpse appeared on the slab. In 1831, the city's poor were desperate and the wealthy were petrified, the population swelling so fast that old class borders could not possibly hold. All the while, early humanitarians were pushing legislation to protect the disenfranchised, the courts were establishing norms of punishment and execution, and doctors were pioneering the science of human anatomy. Vivid and intricate, The Italian Boy restores to history the lives of the very poorest Londoners and offers an unparalleled account of the sights, sounds, and smells of a city at the brink of a major transformation.
The Italian Doctor
by Jennifer TaylorNot the marrying kind? Staff nurse Maggie Carr had hated Luke Fabrizzi on sight and was irritated that everyone else worshiped the handsome new Italian senior resident. Their conflict had stemmed from resentment when Maggie's family had tried to introduce them with marriage in mind. When it dawned on Luke that they could avert their families by staging a relationship, Maggie agreed. It was a truce that led them to the root of their strong feelings and yet another battle--a fight against their real desires and emotions.
Italian Doctor, Full-Time Father
by Dianne DrakeDante has never shied away from a challenge, but winning Catherine back will be the greatest he's ever faced... Dr. Catherine Brannon knows her cool reserve will be tested by her new patient, surgeon-turned-racing-driver Dante Baldassare--her ex-fiance! Dante the sports star is reputed to enjoy fast cars and fast women. But Dante the father, devoted to a small boy, is a different story indeed. Family means everything to Dante--which is why he became a single dad to his orphaned nephew, and lost Catherine in the process. Despite their past, passion sizzles between them, and Dante realizes they have something too precious to lose again. If this is a second chance, he'll stop at nothing to win back Catherine's love.
Italian Doctor, Sleigh-Bell Bride
by Sarah MorganUSA Today–Bestselling Author: A dream date with a doctor makes her feel like a princess—but is true love just a fairy tale for an overworked single mom?Liv Winchester has avoided men and sex since her ex left her with a baby. But new, wealthy trauma consultant Stefano Lucarelli is stunned by her curves and natural nursing talent.Stefano wants to make this overworked single mom feel like the beautiful woman she is again. He gives her two tickets to the Snow Ball, pampering treatments, a designer dress, diamonds, and a babysitter for the night . . . and Liv feels like a princess.Their Snow Ball date is magical. But it’s going to take even more to convince Liv that she’s ready to be Stefano’s for real . . . Praise for the novels of Sarah Morgan“Sweet, sexy and emotionally layered.” —Kirkus Reviews“Morgan masterfully introduces a cast of endearing supporting characters. This touching Christmas tale will [remain] a reader favorite for years to come.” —Publishers Weekly (starred review)
The Italian Doctor's Perfect Family
by Alison RobertsThere's no one else I would want to be the mother of my children Pip Murdoch is torn. She is finally, for the first time in her life, experiencing real love. Toni Costa, the new Italian doctor on the ward, is making her feel things she's never known. But she can't give in to her heart. She has responsibilities that just won't allow it. The gorgeous Italian knows he can help Pip heal the rift between her and her young daughter. He's determined to show her that he'll never leave them, and that together they can be a real family.
The Italian Doctor's Proposal
by Kate HardyThere’s no one else I would want to be the mother of my childrenPip Murdoch is torn. She is finally, for the first time in her life, experiencing real love. Toni Costa, the new Italian doctor on the ward, is making her feel things she’s never known. But she can’t give in to her heart. She has responsibilities that justwon’t allow it.The gorgeous Italian knows he can help Pip heal the rift between her and her young daughter. He’s determined to show her that he’ll never leave them, and that together they can be a real family.
The Italian Effect
by Josie MetcalfeA very Italian remedy Lissa had gone to San Vittorio to discover her Italian roots and heal a broken heart. She found an injured child with a father to die for. The emergency doctor, Mateo Aldarini, couldn't help but show his appreciation to the beautiful English doctor who saved his son's life. He healed Lissa's heart--but then he broke it once more! After his first wife betrayed him and deserted him and his son, Matt could not--however much he wanted to--make himself vulnerable to a woman again. Lissa returned to England--only to discover Italy was where her heart belonged.
The Italian Surgeon
by Meredith WebberShe's devoted to saving others — but only one man can save her! At Jimmie's Children's Unit all eyes are on the newest member of the team — tall, dark and incredibly handsome Italian surgeon Luca Cavaletti. But Luca only has eyes for Dr. Rachel Lerini. Rachel is devoted to her surgical job at Jimmie's — it's her life. She's courageously committed to caring for other people's babies as she couldn't save her own. Luca can sense that she's suffering, but the closer he gets the more she runs away. This dedicated surgeon is determined to make Rachel smile again — and even love again….
Italian Surgeon to the Stars
by Melanie Milburne"You think you can erase what we had?" Celebrity heart surgeon Dr. Alessandro Lucioni might be gorgeous, but I will never forget what we shared in Paris five years ago...or how he broke my heart! And now he's standing in front of me, asking for my help with his young niece-and determined to pick up where we left off! But this time I won't be his consolation prize. I will remain strong. Yet with memories of those magical blazing nights swirling through my mind, he's just so very hard to resist...
The Italian Surgeon's Christmas Miracle
by Alison RobertsNurse Amy Phillips has two things she has to do this Christmas - look after six children, and save their house from being bulldozed by the ruthless new owner! Billionaire surgeon Luke Harrington usually keeps his emotions so close to his chest that some people think he doesn't have any. But, faced with evicting this vibrant brood from the house he's reluctantly inherited, he can't bring himself to be the bad guy. . . He's touched by the warmth and love he sees in Amy and her family. They have none of his wealth, yet their Christmas will be richer than any he's known. So when Amy welcomes him into her life it feels as if he's experienced a Christmas miracle of his own. . .
The Italian's New-Year Marriage Wish (Brides of Penhally Bay)
by Sarah MorganDr. Avanti claims his bride!As the snow falls gently on the Cornish streets, Amy Avanti summons up her courage and opens the door to Penhally Bay Surgery, knowing it will take her back to another life where she was adoringly in love with her husband-and now she's back to finally set him free. But sexy Italian Dr. Marco Avanti simply wants her back by his side, saving lives by day, making love by night. Marco's never stopped loving Amy, and he's going to find out what is causing the shadows under his darling wife's eyes. With the New Year approaching they are going to make a new beginning-and make their marriage magical again!