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Showing 29,251 through 29,275 of 61,215 results

Italian Doctor, Full-Time Father

by Dianne Drake

Dante has never shied away from a challenge, but winning Catherine back will be the greatest he's ever faced... Dr. Catherine Brannon knows her cool reserve will be tested by her new patient, surgeon-turned-racing-driver Dante Baldassare--her ex-fiance! Dante the sports star is reputed to enjoy fast cars and fast women. But Dante the father, devoted to a small boy, is a different story indeed. Family means everything to Dante--which is why he became a single dad to his orphaned nephew, and lost Catherine in the process. Despite their past, passion sizzles between them, and Dante realizes they have something too precious to lose again. If this is a second chance, he'll stop at nothing to win back Catherine's love.

Italian Doctor, Sleigh-Bell Bride

by Sarah Morgan

USA Today–Bestselling Author: A dream date with a doctor makes her feel like a princess—but is true love just a fairy tale for an overworked single mom?Liv Winchester has avoided men and sex since her ex left her with a baby. But new, wealthy trauma consultant Stefano Lucarelli is stunned by her curves and natural nursing talent.Stefano wants to make this overworked single mom feel like the beautiful woman she is again. He gives her two tickets to the Snow Ball, pampering treatments, a designer dress, diamonds, and a babysitter for the night . . . and Liv feels like a princess.Their Snow Ball date is magical. But it’s going to take even more to convince Liv that she’s ready to be Stefano’s for real . . . Praise for the novels of Sarah Morgan“Sweet, sexy and emotionally layered.” —Kirkus Reviews“Morgan masterfully introduces a cast of endearing supporting characters. This touching Christmas tale will [remain] a reader favorite for years to come.” —Publishers Weekly (starred review)

Italian Surgeon to the Stars

by Melanie Milburne

"You think you can erase what we had?" Celebrity heart surgeon Dr. Alessandro Lucioni might be gorgeous, but I will never forget what we shared in Paris five years ago...or how he broke my heart! And now he's standing in front of me, asking for my help with his young niece-and determined to pick up where we left off! But this time I won't be his consolation prize. I will remain strong. Yet with memories of those magical blazing nights swirling through my mind, he's just so very hard to resist...

Itch and Pain: Similarities, Interactions, and Differences

by Gil Yosipovitch Lars Arendt-Nielsen Hjalte Andersen

Providing for the first time a comprehensive overview of the common and different pathways and mechanisms of itch and pain, this unique title explores these two distinct and still somehow similar sensory experiences and utilize the cross-fertilization between the two fields to develop better treatments for patients. Itch and Pain: Similarities, Interactions and Differences is the only available, up-to-date guide to current information in this important area, ideal for basic scientists as well as clinicians in dermatology, pain, neurology, medicine, psychology, or other specialties.

Itch: Basic Mechanisms and Therapy (Basic and Clinical Dermatology)

by Gil Yosipovitch Francis McGlone Malcolm W. Greaves

Offering details on the pharmacology of itch, techniques of itch evaluation, and neurogenic itch, this reference presents new concepts in the neurophysiology and central mechanisms of itch, animal models of itch, and processing of histamine itch in the human cerebral cortex. The text clarifies itch in systemic and skin disease, exploring renal itch

Itch: Mechanisms and Treatment (Frontiers in Neuroscience)

by E. Carstens Tasuku Akiyama

Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direc

Item Writing for Nurse Educators

by Vicki Moran

The book provides guidance and direction for any nurse educator teaching in the professional environment and must write questions to evaluate learning. It covers the basics of item writing and leveling of items using Bloom's taxonomy to the learner. In addition, the book provides stem examples and new types of questions expected on the National Council Licensure Examination for both the registered and practical nurse. Finally, case study development and item analysis are presented.Evaluation of student performance by examination is critical in nursing education, from undergraduate to continuing education programs. Many faculty have reported learning the item writing process in graduate programs, but it is often lost or not reused. Recent research reports nursing faculty using textbook questions that have not been validated and security of the questions have been compromised. A nursing education profession should have the ability to develop items to validate that learning has occurred. The skill is essential to any professional to evaluate the effectiveness of learning.Critical thinking is a skill necessary for licensure examinations, and students often need assistance to learn this skill to pass the licensure examination and practice as a nurse. Therefore, faculty need a source to facilitate their development of the learned item writing process to assist learners and prepare them for practice.This book is unique in that it addresses the basics and the advanced components. In addition, the book provides a substantial list of stems and case study ideas. Finally, the book describes how to use a knowledge-based item and develop an item to a higher level of Blooms' taxonomy and assists those nursing programs that educate international students to adequately prepare for the student to pass the national licensing examination required to practice in the US and Canada.

Iterative Learning Control for Electrical Stimulation and Stroke Rehabilitation

by Chris T. Freeman Eric Rogers Jane H. Burridge Ann-Marie Hughes Katie L. Meadmore

Iterative learning control (ILC) has its origins in the control of processes that perform a task repetitively with a view to improving accuracy from trial to trial by using information from previous executions of the task. This brief shows how a classic application of this technique - trajectory following in robots - can be extended to neurological rehabilitation after stroke. Regaining upper limb movement is an important step in a return to independence after stroke, but the prognosis for such recovery has remained poor. Rehabilitation robotics provides the opportunity for repetitive task-oriented movement practice reflecting the importance of such intense practice demonstrated by conventional therapeutic research and motor learning theory. Until now this technique has not allowed feedback from one practice repetition to influence the next, also implicated as an important factor in therapy. The authors demonstrate how ILC can be used to adjust external functional electrical stimulation of patients' muscles while they are repeatedly performing a task in response to the known effects of stimulation in previous repetitions. As the motor nerves and muscles of the arm reaquire the ability to convert an intention to move into a motion of accurate trajectory, force and rapidity, initially intense external stimulation can now be scaled back progressively until the fullest possible independence of movement is achieved.

J Wave Syndromes

by Charles Antzelevitch Gan-Xin Yan

This book delineates the state of the art of the diagnosis and treatment of J wave syndromes, as well as where future research needs to be directed. It covers basic science, translational and clinical aspects of these syndromes. The authors are leading experts in their respective fields, who have contributed prominently to the literature concerning these topics. J wave syndromes are one of the hottest topics in cardiology today. Cardiac arrhythmias associated with Brugada syndrome (BrS) or an early repolarization (ER) pattern in the inferior or infero-lateral ECG leads are thought to be mechanistically linked to accentuation of transient outward current (Ito)-mediated J waves. Although BrS and ER syndrome (ERS) differ with respect to magnitude and lead location of abnormal J waves, they are thought to represent a continuous spectrum of phenotypic expression termed J wave syndromes. ERS is divided into three subtypes with the most severe, Type 3, displaying an ER pattern globally in the inferior, lateral and right precordial leads. BrS has been linked to mutations in 19 different genes, whereas ERS has been associated with mutations in 7 different genes. There is a great deal of confusion as to how to properly diagnose and treat the J wave syndromes as well as confusion about the underlying mechanisms. The demonstration of successful epicardial ablation of BrS has provided new therapeutic options for the management of this syndrome for which treatment alternatives are currently very limited, particularly in the case of electrical storms caused by otherwise uncontrollable recurrent VT/VF. An early repolarization pattern is observed in 2-5% of the US population. While it is clear that the vast majority of individuals exhibiting an ER pattern are not at risk for sudden cardiac death, the challenge moving forward is to identify those individuals who truly are at risk and to design safe and effective treatments.

JAK-STAT Signaling in Diseases

by Ritobrata Goswami

JAK-STAT pathway is one of the few signal transduction pathways that transduce signals involved in multiple homeostatic biological processes including cell differentiation and proliferation, cell death, hematopoiesis and immune responses. JAK-STAT is an elegant pathway that is relatively simple and evolutionary conserved as gene expression is regulated by external parameters. Activated by growth factors or cytokines, this signal transduction cascade regulates the transcription of genes at the nucleus. Mutations and polymorphisms in JAK-STAT pathway are associated with inflammatory diseases and cancers that could impede regular homeostasis. Features: Details activation and microRNA-mediated regulation of JAK-STAT pathway Provides exclusive information about the association of the pathway in various diseases including allergic inflammation, neuro-inflammatory disorder, atopic dermatitis hematopoietic malignancies, cardiovascular disorder, renal disorder, immunodeficiency, liver fibrosis, diabetes and obesity that affect individuals across the globe Clinical relevance of the signaling cascade has been discussed in context of novel class of therapeutics that targets this pathway. An overview of JAK-STAT signaling pathway and the structure-function relationship of different domains of the cascade are discussed. This book provides detailed information on various diseases that are associated with JAK-STAT pathway. It will act as a very good reference book for basic science researchers, academicians, industry professionals involved in translational research leading to product development. This book will excite future professionals towards better understanding of the regulation of this pathway, its association with other signaling cascades to design novel therapeutics.

JFK's Secret Doctor: The Remarkable Life of Medical Pioneer and Legendary Rock Climber Hans Kraus

by Susan E.B. Schwartz

Set against the grand panorama of twentieth-century world events, it captures the remarkable life and spirit of climbing and medical visionary Hans Kraus (1905-1966). Kraus was taught English by James Joyce, escaped Nazi dominated Europe, and was JFK’s secret back specialist. A legendary rock climber known for hair-raising ascents on two continents, Kraus lived a life filled with tragedy and triumph, intense passion, verve, and a whole lot of guts, glory, and wit. One of the great unsung medical pioneers of the twentieth century, Kraus made headline news throughout the second half of the 1950s, was a guest of honor at Eisenhower’s White House, and was the subject of cover stories in major magazines throughout America, including Sports Illustrated. His pioneering work in muscles and fitness uncovered a shocking truth about a lack of fitness in American children, and his work curing back pain brought him into the Kennedy White House and inner circle of Camelot. Here now is the life of Hans Kraus, including the behind-the-scenes story of Kennedy’s crippling back problems, based on new documentation, including White House medical records and interviews with two Kennedy White House doctors. Skyhorse Publishing, as well as our Arcade imprint, are proud to publish a broad range of books for readers interested in history--books about World War II, the Third Reich, Hitler and his henchmen, the JFK assassination, conspiracies, the American Civil War, the American Revolution, gladiators, Vikings, ancient Rome, medieval times, the old West, and much more. While not every title we publish becomes a New York Times bestseller or a national bestseller, we are committed to books on subjects that are sometimes overlooked and to authors whose work might not otherwise find a home.

JIMD Reports - Case and Research Reports, 2011/2

by Ssiem

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports - Case and Research Reports, 2012/4 (JIMD Reports #9)

by Johannes Zschocke Garry Brown Eva Morava Verena Peters K Michael Gibson

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports - Case and Research Reports, Volume 13

by Johannes Zschocke K. Michael Gibson Garry Brown Eva Morava Verena Peters

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports - Volume 10

by Johannes Zschocke Garry Brown Eva Morava Verena Peters K Michael Gibson

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports, Volume 25

by Johannes Zschocke Eva Morava Verena Peters Matthias Baumgartner Marc Patterson Shamima Rahman

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports, Volume 25

by Johannes Zschocke Eva Morava Verena Peters Matthias Baumgartner Marc Patterson Shamima Rahman

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports, Volume 28

by Johannes Zschocke Eva Morava Verena Peters Matthias Baumgartner Marc Patterson Shamima Rahman

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports, Volume 29

by Johannes Zschocke Eva Morava Verena Peters Matthias Baumgartner Marc Patterson Shamima Rahman

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports, Volume 30

by Johannes Zschocke Eva Morava Verena Peters Matthias Baumgartner Marc Patterson Shamima Rahman

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports, Volume 31

by Johannes Zschocke Eva Morava Verena Peters Matthias Baumgartner Marc Patterson Shamima Rahman

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports, Volume 32

by Johannes Zschocke Eva Morava Verena Peters Matthias Baumgartner Marc Patterson Shamima Rahman

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports, Volume 38 (Jimd Reports #38)

by Johannes Zschocke Eva Morava Verena Peters Matthias Baumgartner Marc Patterson Shamima Rahman

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.The chapter 'Open-Label Single-Sequence Crossover Study Evaluating Pharmacokinetics, Efficacy, and Safety of Once-Daily Dosing of Nitisinone in Patients with Hereditary Tyrosinemia Type 1 (HT-1)' is open access under a CC BY 4.0 license via link.springer.com.

JIMD Reports, Volume 39 (Jimd Reports #39)

by Johannes Zschocke Eva Morava Verena Peters Matthias Baumgartner Marc Patterson Shamima Rahman

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports, Volume 40 (JIMD Reports #40)

by Johannes Zschocke Eva Morava Verena Peters Matthias Baumgartner Marc Patterson Shamima Rahman

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

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Showing 29,251 through 29,275 of 61,215 results