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Multi-Species Dementia Studies: Towards an Interdisciplinary Approach
by Nicholas Jenkins, Anna Jack-Waugh and Louise RitchieDementia is one of the greatest challenges facing humanity in the 21st century. Responding to the global dementia challenge, however, affects more than humans alone. We live in a multi-species world but often think about dementia in mono-species ways. From the lab to the living room, other beings are “on the scene” and our relations with them affect how we understand, experience, and respond to dementia. Drawing on cutting-edge work across the social and biological sciences, this book offers readers the tools to respond to dementia in multi-species ways. By exploring a range of topics, from pathology to personhood, contributors highlight how thinking about dementia as a more-than-human phenomenon may enable new ways of responding to our global dementia challenge.
Multi-System Endocrine Disruption
by Yves Christen Jean-Pierre Bourguignon Bernard Jégou Bernard Kerdelhué Jorma ToppariEndocrine disruption is an expanding field due to the numerous chemicals involved and, as evidenced more recently, the variety of homeostatic systems that they can alter throughout life. The gathering of experts from all over the world should help to identify health disorders that are possibly or likely related to exposure to endocrine disrupters. The research needs have been discussed as well as recommendations prioritizing target groups and following the precautionary principle.
Multi-Target Drug Design Using Chem-Bioinformatic Approaches (Methods in Pharmacology and Toxicology)
by Kunal Roy<p>This detailed book showcases recent advances in computational design of multi-target drug candidates involving various ligand and structure-based strategies. Different chem-bioinformatic modeling strategies that can be applied for design of multi-target drugs as well as important databases and web servers in connection with multi-target drug design are also featured in this collection. Written for the Methods in Pharmacology and Toxicology series, chapters include the kind of key implementation advice that will aid researchers greatly in their laboratory pursuits. <p>Authoritative and practical, Multi-Target Drug Design Using Chem-Bioinformatic Approaches seeks to aid all scientists working in the field of drug discovery research.</p>
Multi-Targeted Approach to Treatment of Cancer
by Kapil Mehta Bharat B. Aggarwal Varsha Gandhi Rajesh Grover Sen PathakIn this book, clinicians and basic scientists from USA, India, and other countries discuss the rationales and clinical experiences with targeted approaches to treat, prevent, or manage cancer. Cancer is a hyperproliferative disorder that is regulated by multiple genes and multiple cell signaling pathways. Genomics, proteomics, and metabolomics have revealed that dysregulation of dozens of genes and their products occur in any given cell type that ultimately leads to cancer. These discoveries are providing unprecedented opportunities to tackle cancer by multi-faceted approaches that target these underpinnings. This book emphasizes a multi-targeted approach to treating cancer, the focus of the 5th International Conference on Translational Cancer Research that was held in Vigyan Bhawan, Delhi (India) from Feb 6-9, 2014.
Multi-axial Fatigue of Trabecular Bone with Respect to Normal Walking
by Ardiyansyah Syahrom Iraj Sadegh Amiri Mohammad MostakhdeminThis book focuses on the analysis and treatment of osteoporotic bone based on drug administration, tracking fatigue behavior and taking into consideration the mechanical interaction of implants with trabecular bone. Weak trabeculae are one of the most important clinical features that need to be addressed in order to prevent hip joint fractures.
Multi-dimensional Vibrational Circular Dichroism
by Akihiko Yamagishi Hisako Sato Jun YoshidaThis book provides the reader with the latest research on vibrational circular dichroism (VCD) spectroscopy including its useful features and applications to many fields. The book starts from an unresolved question in gel chemistry of how component molecules are organized in the flexible fibrils of gels. VCD spectroscopy was successful in giving a clear answer to this mystery. The book also describes a key aspect of this technique lay in the fact that VCD signals were remarkably enhanced when chiral molecules formed a stereoregular molecular array over a few hundred nanometers. VCD spectroscopy was also applied to other topics involving chiral molecules such as the chiral discrimination mechanism in heterogeneous asymmetric catalysis and the build-up of supramolecular chirality in molecular crystals. Furthermore, the book covers the recent instrument developments leading to multi-dimensional VCD measurements with the coordinates of wavenumber, space and time. This progress has opened up new biological and medical applications such as the heterogenous distributions of protein domains in insect wings and the quality control of chiral drugs. The last part of the book presents the possibility of medical diagnosis of Alzheimer’s disease through multi-dimensional VCD analyses. This book appeals not only to researchers and students who study spectroscopy but also to ones in catalysis, biology and medicine as users of the VCD methods.
Multi-parameter Mueller Matrix Microscopy for the Expert Assessment of Acute Myocardium Ischemia (SpringerBriefs in Applied Sciences and Technology)
by Igor Meglinski Victor Bachinsky Alexander Bykov Benjamin Hogan Oleh Ya Vanchulyak Alexander G. Ushenko Yurii A. Ushenko Alexander V. DubolazovThis book provides an essential overview of the basic principles of imaging modalities, accompanied by examples of their applications in modern clinical and associated pre-clinical studies. The monograph is based on the original results of investigation of the efficiency use of laser light and Mueller-matrix polarimetry approach for assessment of myocardial tissues towards confirmation the cause of death. A morphological analysis of necrotic changes in the myocardial tissue of patients that died due to heart attack, coronary heart disease and acute coronary insufficiency was carried out and the data and histological sections of the myocardium inspected utilizing Mueller-matrix mapping of tissue samples with polarized light. A unified optical model of polycrystalline structure of the myocardium is proposed, and the principles and regulations of Mueller-matrix description of its polarization manifestations are explored and developed. The book also provides a statistical and scale-selective wavelet analysis of polarization and Mueller-matrix maps. Finally, the key forensic medical criteria for the differential diagnosis of the cause of death due to necrotic and pathological changes in the morphological structure of the myocardium have been established
Multiband Non-Invasive Microwave Sensor: Design and Analysis
by Brijesh Iyer Nagendra Prasad PathakThis monograph focuses on the design, implementation and characterization of a concurrent dual band RF sensor for non-invasive detection of human vital signs. Exclusive title on multiband short range sensors and their biomedical applications, offers detailed analysis of subsystems based on fabricated and measured prototypes and verifies and discusses the system in the real-time environment. <P><P> Discusses the practical difficulties of the design process and offers case studies based on the design.
Multicomponent Reactions: Synthesis of Bioactive Heterocycles
by K. L. Ameta Anshu DandiaThis timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.
Multicultural Handbook of Food, Nutrition and Dietetics
by Arlene Barton Aruna ThakerMulticultural Handbook of Food, Nutrition and Dietetics is the must have practical resource for dietitians, nutritionists and students working with both well settled but also recently migrated ethnic groups.<P><P>Written by a team of authors drawn from the British Dietetic Association's Specialist Multicultural Nutrition Group the book provides in-depth information to equip the reader in the provision of nutrition advice to minority groups. Spanning a broad range of cultural groups the book seeks to consider religious and cultural requirements in relation to traditional diets; research on migration studies and chronic disease states; and nutrition and dietetic treatment in relation to key chronic diseases.
Multicultural Human Services for AIDS Treatment and Prevention: Policy, Perspectives, and Planning
by Marcia Bok Julio MoralesThis much-needed book presents an introduction and overview of multicultural AIDS issues in social work practice. In a culturally diverse nation, it is essential that professionals look at AIDS within a cultural context in order to find the most effective treatment and prevention strategies for everyone. Emphasizing this need for a culturally sensitive approach, Multicultural Human Services for AIDS Treatment and Prevention increases social workers’often limited knowledge and experience with various social and ethnic groups. It provides specific suggestions and recommendations for program development and acts as a foundation upon which to build new strategies for policy, research, and practice. Multicultural Human Services for AIDS Treatment and Prevention emphasizes the importance of encouraging and sharing research that addresses AIDS and minority populations and assessing prevention, education, and behavioral change strategies from culturally specific and relevant perspectives. It includes chapters focusing on African Americans, Native American Indians, Hawaiians, Puerto Ricans, and Mexican prostitutes--groups that often suffer disproportionately from poverty and its myriad effects. Some topics discussed in the book are: helping clients reduce cultural dissonance how to enhance behavior change child welfare and permanency planning empowerment of clients and health care models knowledge, attitudes, and behaviors regarding HIV/AIDS cultural contradictions and ambivalence in response to AIDSMulticultural Human Services for AIDS Treatment and Prevention is an extremely useful and informative book for all professionals in social work and human services who want to be better prepared to help all groups of people. The book is also an ideal text for upper-level social work students studying topics such as multicultural issues in social work practice, AIDS in a cultural context, and health policy and health care systems.
Multicultural Issues In Rehabilitation And Allied Health
by Paul Leung Carl R. Flowers William B. Talley Priscilla R. SandersonThis book addresses the multicultural issues as they impact the fields of rehabilitation and allied health.
Multicultural Pharmaceutical Education
by Barry BleidtMulticultural Pharmaceutical Education spotlights methods and theory on how to increase representation of minorities in pharmacy schools and practice settings. Many of the ideas presented in this book are unique, and all provide an opportunity for institutions with few minority students to greatly improve their recruitment and retention efforts geared toward these students. The contributing authors, representing all levels of academia--deans, undergraduate students, vice provosts, executive directors, a National Professor of the Year, and faculty members--have all had experience in some aspect of minority pharmaceutical education. It is through their practical experiences that they offer suggestions and commentary on pharmacy programs of study. Historical accounts or examples of success that could be emulated at other institutions are included. With the help of Multicultural Pharmaceutical Education, colleges and universities and their faculty can forge ahead in attracting and retaining minority students to their pharmacy programs and into the world of pharmacy practice. Structured around four major areas (foundation, commitment, actuation, and conclusion), the authors remove the option of traditional excuses of failure in this important area of education. All those involved in pharmacy education should read this book whether deans, admissions counselors, professors, or students. Multicultural Pharmaceutical Education provides an easy-to-read, practical and theoretical approach to improving the opportunity and quality of education that minority students can achieve in pharmaceutical programs.
Multidetector Computed Tomography in Cerebrovascular Disease: CT Perfusion Imaging
by Matthias König Kenneth A Miles James D EastwoodMultidetector Computed Tomography in Cerebrovascular Disease: CT Perfusion Imaging focuses on anatomy and procedural strategy for perfusion CT imaging in clinical neurology and cerebrovascular disease. This text-atlas combines pictures and schematic diagrams to show how this new modality can be used to assess anatomy and guide therapeutic intervent
Multidetector-Row CT of the Thorax
by U. Joseph Schoepf Felix G. MeinelSince the first edition of this book was published in 2004, computed tomography has seen groundbreaking technical innovations that have transformed the field of thoracic imaging and opened novel possibilities for the detection of thoracic pathologies. This book highlights cutting-edge thoracic applications of CT imaging in the context of these technical innovations and discusses the latest opportunities, with critical appraisal of challenges and controversies. All topics are covered by renowned international experts. Chapters from the original edition have been thoroughly updated to reflect the state of the art in technology and scientific evidence, and new contributions included on recent developments such as dual-energy CT and CT imaging in patients with acute chest pain. The book is abundantly illustrated with high-quality images and illustrations.
Multidimensional Approaches to Impacts of Changing Environment on Human Health
by Joystu DuttaThe book discusses the indispensable connection between the environment and health via all possible aspects, focussing on human interactions with the environment. The multi-dimensional field of environmental and human health perspectives with emerging issues and current trends is illustrated through supporting case studies, reviews, research reports and examples. It also covers crucial areas of research such as vector control in a tropical climate, influence of climate change on human health and so forth, including proliferation of microbial diseases. Environmental, health and safety guidelines are discussed as well. Aimed at graduate students and researchers in environmental and medical sciences, health and safety, and ecology, this book Highlights interdisciplinary aspects of environmental changes and associated health risks Explains different aspects of environmental pollution and health risks Includes dedicated chapters on global epidemics and biomedical and municipal waste Contains case studies pertaining to different health and safety issues.
Multidisciplinarity and Interdisciplinarity in Health (Integrated Science #6)
by Nima RezaeiThe contributed volume "Multidisciplinarity and Interdisciplinarity in Health" is a health-centered volume of the Integrated Science Book series. Lack of confidence, lack of expertise, complexities of healthcare, the confusing nature of healthcare environments, and lack of organization and standardization can become obstacles to successful communication. This volume establishes how extensive is the interface between formal sciences and medical sciences on health-related issues. The book provides an overview of the value of the integration of formal, biological, and medical sciences and related products, i.e., health informatics and biomedical engineering, to frame a holistic approach to health systems, healthcare, medical practice, drug discovery, and medical device design. The book also focuses on innovative solutions to the most critical issues of different health crisis, including obesity, infectious outbreaks, and cancer that can be found by using an integrative approach. It also contains the fascinating crossroads between medical sciences, physics, and mind that is discussed from multiple perspectives on cognition, neuroscience, and psychiatry. These multidisciplinary considerations will expand the concepts of creativity, leadership, aesthetics, empathy and mental health.
Multidisciplinary Approach to Ectodermal Dysplasia
by Gianluca Tadini John Timothy Wright Smaïl Hadj-Rabia Holm SchneiderEctodermal Dysplasias (ED) are a diverse group of genetic disorders characterized by congenital defects of two or more ectodermal structures (e.g., sweat gland, tooth, nail, hair), that count about 100 different manifestations. Therefore, the multidisciplinary aspect is a novel but crucial approach to correctly diagnose and treat this kind of diseases and eventually direct patients to specialized centers. A new classification has been proposed as well as new therapeutic options, such as the first prenatal protein replacement therapy for a genetic disease, X-linked hypohidrotic ectodermal dysplasia. The chapters of this book address all relevant topics, starting with epidemiology and embryology, disease classification, molecular biology, EDA1-associated ED, WNT10A-related ED, and p63-related ED. A chapter on ED caused by defects of structural proteins is included and one specifically devoted to differential diagnoses. Specific chapters describe diagnostic assessments and treatment: odontostomatological signs and therapy, ophthalmological or otorhinolaringoiatric signs, other organ involvement, neurological and neuropsychological issues. The final part is dedicated to the most recent developments in molecular therapy and the extremely important role of parents' and patients' associations. Written by internationally renowned experts, this handy resource will be of valuable help for a variety of specialists who deal with ectodermal dysplasias in their daily clinical work, e.g., pediatricians, dermatologists, ENT-specialists, dentists.
Multidisciplinary Approach to Neurofibromatosis Type 1
by Gianluca Tadini Eric Legius Hilde BremsThis volume offers an update of the clinical signs, diagnostic criteria (including molecular diagnosis) and targeted therapies for a particular type of genodermatosis, providing a handy and unique tool for early diagnosis. In recent years, our understanding of genodermatosis and neurocutaneous syndromes has increased, but although Type 1 Neurofibromatosis (NF1) is the most common neuroectodermal disorder and involves a large number of patients and medical disciplines, this syndrome remains underestimated, often misdiagnosed thus leading to inaccurate treatment. The literature on the molecular and pathogenetic aspects is ample, but current clinical approaches, classification, diagnostic criteria and treatment protocols are outdated, creating difficulties in early diagnosis and treatment. As such, a chapter is devoted renewing current diagnostic criteria; it includes clinical and molecular data, to offer a sound, updated discussion basis for a consensus conference.NF1 is a “time-dependent” disorder, meaning that the onset of clinical signs are closely linked to patient age and the book discusses this particularly neglected aspect extensively, as well as the latest molecular diagnosis techniques, which are highly sensitive have not been included in the diagnostic criteria. It also explains the role of the RAS-MAPK pathway and genotype-phenotype correlations. In addition it explores new concepts concerning the pathogenesis of neurofibromas and other hamarthomas and their relevance for a modern therapeutical approach with targeted molecular drugs, as well as newly discovered aspects of NF1 in all internal organs, together with their diagnostic counterparts. A chapter on mosaic neurofibromatosis is also included. There is a particular focus on differential diagnosis (i.e. other diseases with café-au-lait macules), and the recently described Legius syndrome will be presented directly by Prof Eric Legius. All chapters are easy-to-understand, up-to-date, comprehensive and concise tools and are intended for a wide range of professionals involved with genetic disorders of the skin and neurocutaneous diseases: dermatologists, pediatricians, neurologists, oncologists and general practitioners.
Multidisciplinary Approach to Obesity
by Andrea Lenzi Silvia Migliaccio Lorenzo Maria DoniniThis book describes in detail the multidisciplinary management of obesity, providing readers with a thorough understanding of the rationale for a multidisciplinary approach and with the tools required to implement it effectively. The emphasis is on a translational approach, starting from basic concepts and fundamental mechanisms of the pathology and clinical morbidity. Experts in the field discuss the full range of relevant topics, including the significance of physical exercise, psychological issues, nutritional strategies, pharmacological options and bariatric surgery. Put another way, the book covers all aspects from the bench to the bedside. Physicians, scientists and postgraduate students will all find it to be invaluable in understanding the causes and optimal management of obesity, which has rapidly become a major public health problem.
Multidisciplinary Approach to Surgical Oncology Patients
by M. D. RayThe book covers the basic concept of surgical and oncosurgical disciplines as a whole, as well as the management of surgical patients from pre-op preparation to discharge, i.e., all the basics needed for a successful outcome for oncosurgical patients. It covers surgical safety, the consumer protection act, medico-legal aspects, the importance of documentation, research and publications, and managing complications. The respective chapters cover pre-operative, intra-operative, and ICU management of cancer patients, based on a multi-disciplinary approach. Additionally, they highlight recent advances in surgical oncology and so-called incurable cancers. Edited and written by an interdisciplinary team of experts in oncology and palliative care, the book is intended as a clinically useful guide to the overlapping topics of pain management in cancer patients and the treatment of cancer in patients with multiple co-morbidities like cardiovascular, respiratory disease, hypertension and diabetes mellitus. Given its scope, it will benefit multi-disciplinary oncologists, pain, palliative and intensive care experts, as well as students of surgical disciplines, from MBBS, MS and DNB, to MRCS, MCh and FRCS.
Multidisciplinary Approaches to Common Surgical Problems
by Robert LimEmergent general surgical diseases are the most frequent causes of in-hospital deaths and are the most costly diseases to treat. The purpose of this book is to provide clinicians with an understanding of their roles and that of other disciplines for the treatment of acute and emergent surgical diseases. It is also designed to give a clear pathway for using multiple disciplines to manage these diseases. The text details over 20 problems routinely seen in clinical practice and approaches the disease from the perspective of experts within the different specialties. It provides a comprehensive, evidenced-based overview and the most up-to-date technology available in clinical practice. An emphasis on new, less invasive techniques that may have a broader range of indications in the future is also included. Ultimately the reader will have a better understanding of these acute problems, the other specialties they work with, and when to integrate these other specialties when they encounter these urgent clinical scenarios.
Multidisciplinary Approaches to Forensic Archaeology: Topics discussed during the European Meetings on Forensic Archaeology (EMFA) (Soil Forensics)
by Pier Matteo Barone W. J. GroenThis book will present the most advanced research on forensic archaeology presented during the annual European meetings in the last 3 years. Thanks to the broad nature of the chapters presented, this book will show not only different approaches and different crime scenes around Europe, but also how every single European law enforcement has faced forensic investigations. This book shows forensic archaeology as practiced in this legal context, emerging and solidifying in many European countries, differing in some respects because of differences in legal systems but ultimately sharing common grounds. Differently from similar books, this will be not only a collection of research and case studies in which forensic practitioners demonstrate the extent and complexity of the various aspects of forensic archaeology, but also it will show the necessity of co-operation as a condition for any work in forensic archaeology among scientists of different disciplines and law enforcers.
Multidisciplinary Care of Urinary Incontinence
by Vincent Tse Lewis ChanMultidisciplinary Care of Urinary Incontinence - a Handbook for Health Professionals effectively uses a multidisciplinary approach to assist health professionals in their care of patients with urinary incontinence. It is recognized that the best outcomes are achieved by a multidisciplinary team approach especially with regard to complex cases and care of the elderly. This book is written by expert authors from around the world with a wealth of experience in conducting clinics on pelvic floor, aged care voiding dysfunction and neuro-rehabilitation. The text is illustrated throughout and contains case-studies with input and practical tips from the different health disciplines at each point. Each chapter concludes with a list of seminal publications and web-based resources to assist the reader in the clinical environment. Multidisciplinary Care of Urinary Incontinence - a Handbook for Health Professionals is of benefit to medical and allied health disciplines including family physicians, nurses, urologists, gynecologists, physiotherapists, geriatricians, neurologists and rehabilitation specialists.
Multidisciplinary Care of the Head and Neck Cancer Patient (Cancer Treatment and Research #174)
by Ellie Maghami Allen S. HoThis book identifies key treatment challenges and unique care considerations in patients with head and neck cancers, providing a comprehensive guide to patient management that illustrates the critical importance of a multidisciplinary approach in achieving optimal oncological, functional, and survival outcomes. It covers all relevant specialties, including dental and oral medicine, medical oncology, radiation oncology, surgical oncology, and reconstructive surgery. It highlights the vital role played by ancillary head and neck cancer services, such as speech and swallowing therapy, occupational and physical therapy, and nutritional therapy in offering essential physical and psychological support from the time of diagnosis onward. The closing chapters address post-treatment issues, including those relating to survivorship, surveillance, and end-of-life care. Multidisciplinary care is perhaps even more important for patients with head and neck cancers than for other cancer patients, and in addressing all its aspects this book is invaluable for a wide range of practitioners.