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Multimodal Retrieval in the Medical Domain
by Henning Müller Oscar Alfonso Jimenez del Toro Allan Hanbury Georg Langs Antonio Foncubierta RodriguezThis book constitutes the proceedings of the First International Workshop on Multimodal Retrieval in the Medical Domain, MRMD 2015, held in Vienna, Austria, on March 29, 2015. The workshop was held in connection with ECIR 2015. The 14 full papers presented, including one invited paper, a workshop overview and five papers on the VISCERAL Retrieval Benchmark, were carefully reviewed and selected from 18 submissions. The papers focus on the following topics: importance of data other than text for information retrieval; semantic data analysis; scalability approaches towards big data sets.
Multimodal Sentiment Analysis (Socio-Affective Computing #8)
by Amir Hussain Erik Cambria Soujanya PoriaThis latest volume in the series, Socio-Affective Computing, presents a set of novel approaches to analyze opinionated videos and to extract sentiments and emotions. Textual sentiment analysis framework as discussed in this book contains a novel way of doing sentiment analysis by merging linguistics with machine learning. Fusing textual information with audio and visual cues is found to be extremely useful which improves text, audio and visual based unimodal sentiment analyzer. This volume covers the three main topics of: textual preprocessing and sentiment analysis methods; frameworks to process audio and visual data; and methods of textual, audio and visual features fusion. The inclusion of key visualization and case studies will enable readers to understand better these approaches. Aimed at the Natural Language Processing, Affective Computing and Artificial Intelligence audiences, this comprehensive volume will appeal to a wide readership and will help readers to understand key details on multimodal sentiment analysis.
Multimodal Treatment of Acute Psychiatric Illness: A Guide for Hospital Diversion
by Glendon Moriarty Justin SimpsonThe multimodal treatment of acute psychiatric illness involves a set of integrated, systematic interventions that stabilize individuals with severe mental illness and help them avoid unnecessary psychiatric hospitalization. This volume focuses on those suffering from schizophrenia, schizoaffective disorder, bipolar disorder, major depressive disorder, severe anxiety, and substance dependence, and provides individual practitioners and professional teams with the tools for responding to crisis and delivering acute care. The authors bolster the text with real-world case examples, helpful diagrams, and printable worksheets.
Multimodal Treatment of Recurrent Pelvic Colorectal Cancer
by Giovanni Maria RomanoThis book analyzes all aspects of modern multimodal treatment of locally recurrent rectal cancer in the pelvis in order to offer a panoramic overview of the different therapeutic options and enable the reader to balance their benefits and drawbacks. Indications for surgery and the surgical techniques themselves, including reconstruction techniques after major exenterative surgery, are clearly described and evaluated. The role of new imaging tools, such as MRI and PET-CT, in staging recurrences and guiding therapy is assessed and detailed consideration is given to the use of neoadjuvant and iterative radiotherapy and the indications for systemic chemotherapy. Morbidity, mortality, oncologic outcomes, and quality of life issues are carefully analyzed and options for pain control and palliation are examined. Finally, a national survey is presented on the state of the art in the surgical treatment of locally recurrent rectal cancer in Italy. While there has been a dramatic fall in the incidence of local pelvic recurrences, their treatment remains a major clinical challenge which requires a multidisciplinary approach and careful selection of the most appropriate strategy in each case. This book will aid practitioners in making the correct decisions in individual patients.
Multimodality Imaging Innovations In Adult Congenital Heart Disease: Emerging Technologies and Novel Applications (Congenital Heart Disease in Adolescents and Adults)
by Pastora Gallego Israel ValverdeThis book focuses on congenital heart disease (CHD) and emerging imaging technologies. It covers all clinically relevant aspects of the fascinating new cardiac imaging technologies, including a comprehensive explanation of their basic principles, practical aspects of novel clinical applications, and detailed descriptions of specific uses in the broad spectrum of clinically important adult CHD. Innovations and emerging technologies for diagnosis and therapeutics, evaluation and treatment are continually evolving, and due to these advances in non-invasive diagnosis, there has been a significant improvement in the survival rates for CHD patient. Novel approaches to trans-catheter interventions and advances in echocardiography, MRI and CT imaging are being developed and incorporated into routine clinical practice, while emerging three-dimensional printing technologies are fundamentally affecting patient care, research, trainee education, and interactions between multidisciplinary teams, patients, and caregivers. In addition, translational technologies on the horizon promise to take this nascent field even further. Exploring the applicability of these emerging technologies in improving our understanding of complex congenital cardiac defect anatomy and physiology will provide new treatment options for this unique population. Written by experts in the field who are also involved in patient care, this book discusses the practical application of innovations in advanced multimodality imaging in the daily clinical routine and offers tips and tricks for beginners.
Multimodality Imaging and Intervention in Oncology
by Emanuele Neri Paola Anna ErbaThis book provides the reader with a focused review of multimodality imaging strategies (radiology and molecular imaging) in staging and re-staging the major types of cancer (i.e. thyroid, breast, colon-rectum, lung, prostate, pancreas, liver, head and neck, and hematological cancer), including rare neoplasms. In addition to presenting the possible diagnostic pathways for all oncologic diseases, the book identifies those interventions currently available in clinical practice (these being a branch of interventional radiology), while also examining and detailing molecular radiotherapy strategies. The work has an interdisciplinary appeal and, thanks to its highly informative and cutting-edge coverage, professionals as well as advanced students and residents in radiology, oncology and surgery will find it of particular interest.
Multimodality Imaging for Cardiac Valvular Interventions, Volume 1 Aortic Valve: From Diagnosis to Decision-Making
by Francesco Maisano Philipp Kaufmann Hatem Alkadhi Michel Zuber Alberto Pozzoli Edwin HoThis book provides a practically applicable guide to the use of multimodality imaging for managing aortic valve disorders. Details of how to successfully diagnose a range of aortic valve diseases is presented, with detailed information covered on the techniques and relevant criteria for pre-operative screening, surgical and transcatheter planning, intraprocedural imaging and related postoperative follow-up. Multimodality Imaging for Cardiac Valvular Interventions, Volume 1 Aortic Valve: From Diagnosis to Decision-Making enables the reader to develop a thorough understanding and confidence of how to make appropriate clinical decisions when confronted by a range of aortic valve diseases. It is therefore a key resource for practicing cardiac imagers, cardiologists and interventional cardiologists who encounter these patients in their day-to-day clinical practice and trainees in cardiology seeking insight on the appropriate management of these patients.
Multimodality Imaging for Transcatheter Aortic Valve Replacement
by James K. Min Daniel S. Berman Jonathon LeipsicThis book is ideal for cardiovascular imagers of all backgrounds as well as proceduralists (surgeons and interventional cardiologists) performing TAVR. This text is also of value for the physicians and nurses involved in the care of these patients, and for fellows-in-training. This practical text brings together guidance on using multi-modality imaging in one book and highlights its usage with a focus on patient care. Pre-procedural, Intra-procedural and Long-term follow up), this review offers expert opinion and evidence-based guidance on how to incorporate the various imaging modalities at each step in the care of a TAVR patient. Although much has been learned in the short span of time since TAVR was introduced into the field, our book will also offer recommendations for clinically-relevant research areas that will lead to best practice strategies for incorporating multi-modality imaging into TAVR patient care.
Multimodality Imaging: For Intravascular Application
by Zhongping Chen Qifa ZhouThis book provides a state-of-the-art overview of the combined use of imaging modalities to obtain important functional and morphological information on intravascular disease and enhance disease detection. It discusses the integration of intravascular ultrasound (IVUS, intravascular optical coherence tomography (OCT), intravascular photoacoustic imaging (IVPA) and acoustic radiation force optical coherence elastography (ARF-OCE), and introduces the integration of multimodality imaging systems, such as IR and florescence. It includes the latest research advances and numerous imaging photos to offer readers insights into current intravascular applications. It is a valuable resource for students, scientists and physicians wanting to gain a deeper understanding of multimodality imaging tools.
Multimodality Management of Borderline Resectable Pancreatic Cancer
by Matthew H.G. Katz Syed A. AhmadThis volume provides the most comprehensive coverage of clinical management of borderline resectable pancreatic cancer available. Authored by leaders in the field, the book focuses on current clinical management of this disease stage, the importance of multimodality treatment algorithms, and an interdisciplinary approach to care. Surgical chapters are well-illustrated to provide surgeons and surgical trainees with important technical pearls. Clinical trials and trial design are also discussed. Multimodality Management of Borderline Resectable Pancreatic Cancer is a valuable resource for gastroenterologists, medical oncologists, radiation oncologists, surgical oncologists, general surgeons, and trainees interested in the treatment of pancreatic cancer.
Multiobjective Optimization Algorithms for Bioinformatics
by Ujjwal Maulik Sanghamitra Bandyopadhyay Anirban Mukhopadhyay Sumanta RayThis book provides an updated and in-depth introduction to the application of multiobjective optimization techniques in bioinformatics. In particular, it presents multiobjective solutions to a range of complex real-world bioinformatics problems. The authors first provide a comprehensive yet concise and self-contained introduction to relevant preliminary methodical constructions such as genetic algorithms, multiobjective optimization, data mining and several challenges in the bioinformatics domain. This is followed by several systematic applications of these techniques to real-world bioinformatics problems in the areas of gene expression and network biology. The book also features detailed theoretical and mathematical notes to facilitate reader comprehension. The book offers a valuable asset for a broad range of readers – from undergraduate to postgraduate, and as a textbook or reference work. Researchers and professionals can use the book not only to enrich their knowledge of multiobjective optimization and bioinformatics, but also as a comprehensive reference guide to applying and devising novel methods in bioinformatics and related domains.
Multiorgan Procurement for Transplantation
by Paolo Aseni Antonino M. Grande Luciano CarlisThis well-illustrated handbook provides answers to important questions that may arise during the retrieval of multiple organs for transplantation and offers step-by-step descriptions of current surgical techniques for procurement of the various thoracic and abdominal organs, including heart, lung, liver, intestine, pancreas, and kidney. The coverage includes detailed instruction on liver splitting techniques and on living donor liver hepatectomies and laparoscopic and robot-assisted nephrectomy for transplantation. In addition, guidance is provided on preoperative evaluation for multiorgan donation, contraindications, management for organ retrieval in deceased donors, and organ preservation. The advice offered and the questions addressed will be of relevance not only to transplant surgeons, trainees, and fellows but also to all other professionals involved in organ transplantation, including nursing staff in intensive care units and emergency rooms.
Multiparameter Flow Cytometry in the Diagnosis of Haematologic Malignancies
by Anna Porwit Marie Christine BeneMaster implementation of the techniques of flow cytometry in diagnosing complex haematological diseases and malignancies in patients, worldwide. Featuring World Health Organization recommendations on pre-analytical steps, instrument settings and panel construction, this invaluable manual offers invaluable support for those researching, practising and analyzing the cause of hematological malignancies. Authored by leading experts, this book puts flow-cytometry into everyday context. With a focus on multicolour panels, the manual provides readers an experienced understanding of effective, implementation techniques. Practitioners of all levels are offered a background in a variety of diseases presented alongside the most current methodology. Wide-ranging and comprehensive; detailed images of healthy blood, bone marrow and lymph-nodes are illustrated throughout, allowing for effective diagnosis. Through engaging with differential diagnoses, the manual offers an understanding of similar symptoms and mimicking malignancies, avoiding inaccurate results. Featuring in-depth descriptions of chronic diseases; users can reach accurate diagnosis, first time. Focus on 8-10 multicolor panels, allowing readers to effectively understand how to plan and apply the panels in the most constructive way; Features up-to-date information and references, compiled by experts in the field; Illustrations are made using multiple analysis software options, highlighting the key features of various diseases, to best inform on diagnostic features.
Multiparameter Flow Cytometry in the Diagnosis of Hematologic Malignancies
by Anna Porwit Marie-Christine BénéMaster the implementation of flow cytometry techniques in diagnosing complex hematologic diseases and malignancies in patients with this comprehensive and practical guide. Featuring updated recommendations on pre-analytical steps, instrument settings and panel construction, this manual offers invaluable support for those diagnosing, treating and researching hematologic malignancies. Written by leading experts in the field, this book puts flow cytometry into everyday context. Through engaging with differential diagnoses, the manual offers an accurate description of specific features of malignancies and mimicking conditions. It also places flow cytometry in the scope of integrated diagnosis according to WHO and ICC classifications. Fully updated throughout, this second edition provides new literature and concepts, and presents new AI-based analytical methods. Richly illustrated and in full colour, this book is an ideal resource for those working in flow cytometry laboratories.
Multiparametric Ultrasound Diagnosis of Breast Diseases
by Alexander N. Sencha Gennady T. SukhikhThis richly illustrated book provides a comprehensive overview of the use of current ultrasound techniques, including contrast-enhanced ultrasound and ultrasonic elastography, in the diagnosis of breast disease. The advantages and pitfalls of the various imaging modalities are identified, and it is explained how combined use of the modalities – multiparametric ultrasound – aids diagnosis and in particular assists in the differentiation of benign and malignant disease. Readers will find detailed description and illustration of the imaging appearances of age-related features (including in children and adolescents), the most important benign diseases, different forms of breast cancer, mammary gland pathology in the contexts of pregnancy and female reproductive system disease, chest gland pathology in males, and recurrent and metastatic disease. In addition, ultrasound-guided breast interventions and imaging of breast implants are discussed. Specialists in ultrasound diagnostics, radiologists, oncologists, and surgeons will all find this topical book to be both interesting and helpful in daily clinical practice.
Multiparticulate Drug Delivery
by Ali R. Rajabi-SiahboomiAuthored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery. The book will cover market trends, potential benefits and formulation challenges for various types of multiparticulate systems. Drug solubility, dose, chemistry and therapeutic indications as well as excipient suitability coupled with manufacturing methods will be fully covered. Key approaches for taste-masking, delayed release and extended release of multiparticulates systems are of significant interest, especially their in-vivo and in-vitro performance. In addition, the principles of scale-up, QbD, and regulatory aspects of common materials used in this technology will be explained, as well as recent advances in materials and equipment enabling robust, flexible and cost-effective manufacture. Case studies illustrating best practices will also make the book a valuable resource to pharmaceutical scientists in industry and academia.
Multiphoton Microscopy (Neuromethods #148)
by Espen HartveitThis volume covers the latest techniques and strategies used in multi-photon excitation (MPE) microscopy. Chapters in this book cover the fundamentals of MPE microscopy as applied to both in vitro and in vivo experimental systems; information on how to combine MPE microscopy with targeted electrophysiological recordings, calcium imaging, and transmembrane voltage imaging; methods to investigate cellular and large-scale neural morphology; signaling in astrocytes; and ways to use MPE microscopy to study the retina. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.Comprehensive and thorough, Multiphoton Microscopy is a valuable resource for both expert and novice researchers interested in expanding their knowledge and research in this rapidly developing field.
Multiphysics Modeling with Application to Biomedical Engineering
by Z. YangThe aim of this book is to introduce the simulation of various physical fields and their applications for biomedical engineering, which will provide a base for researchers in the biomedical field to conduct further investigation. The entire book is classified into three levels. It starts with the first level, which presents the single physical fields including structural analysis, fluid simulation, thermal analysis, and acoustic modeling. Then, the second level consists of various couplings between two physical fields covering structural thermal coupling, porous media, fluid structural interaction (FSI), and acoustic FSI. The third level focuses on multi-coupling that coupling with more than two physical fields in the model. Each part in all levels is organized as the physical feature, finite element implementation, modeling procedure in ANSYS, and the specific applications for biomedical engineering like the FSI study of Abdominal Aortic Aneurysm (AAA), acoustic wave transmission in the ear, and heat generation of the breast tumor. The book should help for the researchers and graduate students conduct numerical simulation of various biomedical coupling problems. It should also provide all readers with a better understanding of various couplings.
Multiple Autisms: Spectrums of Advocacy and Genomic Science
by Jennifer S. SinghIs there a gene for autism? Despite a billion-dollar, twenty-year effort to find out—and the more elusive the answer, the greater the search seems to become—no single autism gene has been identified. In Multiple Autisms, Jennifer S. Singh sets out to discover how autism emerged as a genetic disorder and how this affects those who study autism and those who live with it. This is the first sustained analysis of the practices, politics, and meaning of autism genetics from a scientific, cultural, and social perspective.In 2004, when Singh began her research, the prevalence of autism was reported as 1 in 150 children. Ten years later, the number had jumped to 1 in 100, with the disorder five times more common in boys than in girls. Meanwhile the diagnosis changed to &“autistic spectrum disorders,&” and investigations began to focus more on genomics than genetics, less on single genes than on hundreds of interacting genes. Multiple Autisms charts this shift and its consequences through nine years of ethnographic observations, analysis of scientific and related literatures, and morethan seventy interviews with autism scientists, parents of children with autism, and people on the autism spectrum. The book maps out the social history of parental activism in autism genetics, the scientific optimism about finding a gene for autism and the subsequent failure, and the cost in personal and social terms of viewing and translating autism through a genomic lens.How is genetic information useful to people living with autism? By considering this question alongside the scientific and social issues that autism research raises, Singh&’s work shows us the true reach and implications of a genomic gaze.
Multiple Biological Sequence Alignment: Scoring Functions, Algorithms and Evaluation
by Yi Pan Ken Nguyen Xuan GuoCovers the fundamentals and techniques of multiple biological sequence alignment and analysis, and shows readers how to choose the appropriate sequence analysis tools for their tasks This book describes the traditional and modern approaches in biological sequence alignment and homology search. This book contains 11 chapters, with Chapter 1 providing basic information on biological sequences. Next, Chapter 2 contains fundamentals in pair-wise sequence alignment, while Chapters 3 and 4 examine popular existing quantitative models and practical clustering techniques that have been used in multiple sequence alignment. Chapter 5 describes, characterizes and relates many multiple sequence alignment models. Chapter 6 describes how traditionally phylogenetic trees have been constructed, and available sequence knowledge bases can be used to improve the accuracy of reconstructing phylogeny trees. Chapter 7 covers the latest methods developed to improve the run-time efficiency of multiple sequence alignment. Next, Chapter 8 covers several popular existing multiple sequence alignment server and services, and Chapter 9 examines several multiple sequence alignment techniques that have been developed to handle short sequences (reads) produced by the Next Generation Sequencing technique (NSG). Chapter 10 describes a Bioinformatics application using multiple sequence alignment of short reads or whole genomes as input. Lastly, Chapter 11 provides a review of RNA and protein secondary structure prediction using the evolution information inferred from multiple sequence alignments. * Covers the full spectrum of the field, from alignment algorithms to scoring methods, practical techniques, and alignment tools and their evaluations * Describes theories and developments of scoring functions and scoring matrices *Examines phylogeny estimation and large-scale homology search Multiple Biological Sequence Alignment: Scoring Functions, Algorithms and Applications is a reference for researchers, engineers, graduate and post-graduate students in bioinformatics, and system biology and molecular biologists. Ken Nguyen, PhD, is an associate professor at Clayton State University, GA, USA. He received his PhD, MSc and BSc degrees in computer science all from Georgia State University. His research interests are in databases, parallel and distribute computing and bioinformatics. He was a Molecular Basis of Disease fellow at Georgia State and is the recipient of the highest graduate honor at Georgia State, the William M. Suttles Graduate Fellowship. Xuan Guo, PhD, is a postdoctoral associate at Oak Ridge National Lab, USA. He received his PhD degree in computer science from Georgia State University in 2015. His research interests are in bioinformatics, machine leaning, and cloud computing. He is an editorial assistant of International Journal of Bioinformatics Research and Applications. Yi Pan, PhD, is a Regents' Professor of Computer Science and an Interim Associate Dean and Chair of Biology at Georgia State University. He received his BE and ME in computer engineering from Tsinghua University in China and his PhD in computer science from the University of Pittsburgh. Dr. Pan's research interests include parallel and distributed computing, optical networks, wireless networks and bioinformatics. He has published more than 180 journal papers with about 60 papers published in various IEEE/ACM journals. He is co-editor along with Albert Y. Zomaya of the Wiley Series in Bioinformatics.
Multiple Blessings: Surviving to Thriving with Twins and Sextuplets
by Jon Gosselin Kate Gosselin Beth CarsonAutobiography of a couple who had twins, and three years, sextuplets. Kate chronicles the emotional and exhausting challenges she and Jon faced from conception of the babies through their first two years of life.
Multiple Case Study Analysis
by Robert E. StakeExamining situational complexity is a vital part of social and behavioral science research. This engaging text provides an effective process for studying multiple cases--such as sets of teachers, staff development sessions, or clinics operating in different locations--within one complex program. The process also can be used to investigate broadly occurring phenomena without programmatic links, such as leadership or sibling rivalry. Readers learn to design, analyze, and report studies that balance common issues across the group of cases with the unique features and context of each case. Three actual case reports from a transnational early childhood program illustrate the author's approach, and helpful reproducible worksheets facilitate multicase recording and analysis.
Multiple Choice Questions for Haematology and Core Medical Trainees
by Barbara J. BainWritten to help haematology and general medical trainees evaluate their own knowledge, and particularly useful for those preparing for the Part 1 examination of the Royal College of Pathologists. This exam-centered book will also be of use to core medical trainees preparing for the examinations of the Royal College of Physicians and the Royal Australasian College of Physicians and to haematology and general medicine trainees in other countries where methods of examination are similar. The 200 questions are presented in two formats, Single Best Answer and Extended Matching Question, and comes complete wih detailed feedback and, when appropriate, relevant references are given for each question so that those who select the wrong answer will understand why another answer is better. Quick reference question book, ideal for examination preparation Includes 50 SBA questions, ideal for the Part 1 and Part 2 MRCP examinations, which although having a general medical slant, are also appropriate for haematology specialist trainees Includes 70 SBA multiple choice questions appropriate for haematology specialist trainees but also useful to core medical trainees Includes 30 EMQs suitable for those taking Part 1 of the FRCPath examination Questions come complete with fully referenced answers and discussion points This book provides an educational tool for training as well as an ideal way to prepare for examinations and is also of value to those know examine of haematology and haematopathology.
Multiple Choice Questions in Regional Anaesthesia
by Rajesh Gupta Dilip PatelInterest in regional anaesthesia has been flourishing for a number of reasons, including in particular the feasibility of ultrasound-guided peripheral nerve blocks. This trend is reflected in the growing popularity of fellowships in regional anaesthesia. The syllabus for such fellowship examinations is vast, and the current book aims to provide suitable guidance by presenting typical multiple choice questions with accompanying answers, in detail when necessary. The entire syllabus is covered in four sections that address basic principles and equipment, peripheral nerve blocks, central neuraxial blocks, and regional anaesthesia and acute pain. This book will be especially useful for those preparing for European Society of Regional Anaesthesia diploma examinations or for the regional anaesthesia component of FRCA examinations. It is also highly relevant to equivalent U.S. and Canadian examinations and will be helpful to all who require a self-assessment tool in the subject.
Multiple Choice Questions in Regional Anaesthesia
by Rajesh Gupta Dilip PatelThis revised and expanded second edition is a learning and self-assessment tool for the study of regional anesthesia. The first part deals with the basic principles of regional anesthesia and the equipment used. This is followed by sections on peripheral nerve blocks, central neuraxial blocks and pain. Pediatric regional anesthesia is discussed along with the adult blocks. There are additional MCQs in each section, and new chapters on the anatomy, physiology, assessment and monitoring of acute pain. This book is aimed at those studying for the European Society of Regional Anesthesia Diploma Examinations, regional anesthesia component of FRCA examinations, and exit examinations for regional anesthesia fellowships. It is also relevant to the regional anesthesia component of US Board examinations and the Canadian fellowships in regional anesthesia.