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Multivariate Analysis of Ecological Data with ade4
by Jean Thioulouse Stéphane Dray Anne-Béatrice Dufour Aurélie Siberchicot Thibaut Jombart Sandrine PavoineThis book introduces the ade4 package for R which provides multivariate methods for the analysis of ecological data. It is implemented around the mathematical concept of the duality diagram, and provides a unified framework for multivariate analysis. The authors offer a detailed presentation of the theoretical framework of the duality diagram and also of its application to real-world ecological problems. These two goals may seem contradictory, as they concern two separate groups of scientists, namely statisticians and ecologists. However, statistical ecology has become a scientific discipline of its own, and the good use of multivariate data analysis methods by ecologists implies a fair knowledge of the mathematical properties of these methods.The organization of the book is based on ecological questions, but these questions correspond to particular classes of data analysis methods. The first chapters present both usual and multiway data analysis methods. Further chapters are dedicated for example to the analysis of spatial data, of phylogenetic structures, and of biodiversity patterns. One chapter deals with multivariate data analysis graphs.In each chapter, the basic mathematical definitions of the methods and the outputs of the R functions available in ade4 are detailed in two different boxes. The text of the book itself can be read independently from these boxes. Thus the book offers the opportunity to find information about the ecological situation from which a question raises alongside the mathematical properties of methods that can be applied to answer this question, as well as the details of software outputs. Each example and all the graphs in this book come with executable R code.
Multivariate Data Integration Using R: Methods and Applications with the mixOmics Package (Chapman & Hall/CRC Computational Biology Series)
by Kim-Anh LeCao Zoe Marie WelhamLarge biological data, which are often noisy and high-dimensional, have become increasingly prevalent in biology and medicine. There is a real need for good training in statistics, from data exploration through to analysis and interpretation. This book provides an overview of statistical and dimension reduction methods for high-throughput biological data, with a specific focus on data integration. It starts with some biological background, key concepts underlying the multivariate methods, and then covers an array of methods implemented using the mixOmics package in R. Features: Provides a broad and accessible overview of methods for multi-omics data integration Covers a wide range of multivariate methods, each designed to answer specific biological questions Includes comprehensive visualisation techniques to aid in data interpretation Includes many worked examples and case studies using real data Includes reproducible R code for each multivariate method, using the mixOmics package The book is suitable for researchers from a wide range of scientific disciplines wishing to apply these methods to obtain new and deeper insights into biological mechanisms and biomedical problems. The suite of tools introduced in this book will enable students and scientists to work at the interface between, and provide critical collaborative expertise to, biologists, bioinformaticians, statisticians and clinicians.
Multivariate Exponential Families: A Concise Guide to Statistical Inference (SpringerBriefs in Statistics)
by Udo Kamps Stefan BedburThis book provides a concise introduction to exponential families. Parametric families of probability distributions and their properties are extensively studied in the literature on statistical modeling and inference. Exponential families of distributions comprise density functions of a particular form, which enables general assertions and leads to nice features. With a focus on parameter estimation and hypotheses testing, the text introduces the reader to distributional and statistical properties of multivariate and multiparameter exponential families along with a variety of detailed examples. The material is widely self-contained and written in a mathematical setting. It may serve both as a concise, mathematically rigorous course on exponential families in a systematic structure and as an introduction to Mathematical Statistics restricted to the use of exponential families.
Multivariate Methods of Representing Relations in R for Prioritization Purposes
by Ganapati P. Patil Wayne L. MyersThis monograph is multivariate, multi-perspective and multipurpose. We intend to be innovatively integrative through statistical synthesis. Innovation requires capacity to operate in ways that are not ordinary, which means that conventional computations and generic graphics will not meet the needs of an adaptive approach. Flexible formulation and special schematics are essential elements that must be manageable and economical.
Multivariate Statistical Machine Learning Methods for Genomic Prediction
by José Crossa Osval Antonio Montesinos López Abelardo Montesinos LópezThis book is open access under a CC BY 4.0 licenseThis open access book brings together the latest genome base prediction models currently being used by statisticians, breeders and data scientists. It provides an accessible way to understand the theory behind each statistical learning tool, the required pre-processing, the basics of model building, how to train statistical learning methods, the basic R scripts needed to implement each statistical learning tool, and the output of each tool. To do so, for each tool the book provides background theory, some elements of the R statistical software for its implementation, the conceptual underpinnings, and at least two illustrative examples with data from real-world genomic selection experiments. Lastly, worked-out examples help readers check their own comprehension.The book will greatly appeal to readers in plant (and animal) breeding, geneticists and statisticians, as it provides in a very accessible way the necessary theory, the appropriate R code, and illustrative examples for a complete understanding of each statistical learning tool. In addition, it weighs the advantages and disadvantages of each tool.
Mum, Me and Cancer
by Pam WestonHaving your father die and your mother come to live with you is bad enough, especially when she is diagnosed with cancer. How will you manage with her in your house? What about organising all the support she needs? How do you balance her needs against a growing number of grandchildren? Then just when you think you've got it covered, you find a lump in your own breast… This is one woman's true story of what happened to her.
Munchausen by Proxy and Other Factitious Abuse: Practical and Forensic Investigative Techniques (Practical Aspects of Criminal and Forensic Investigations #64)
by Kathryn ArtingstallThis book covers Munchausen and Munchausen by Proxy (MBP) though the terms have recently changed. The 2013 DSM-V—the update to the American Psychiatric Association's (APA) diagnostic and classification tool—has classified both Munchausen and MBP as "Factitious Systematic Abuse." While thought to have occurred primarily with children and their caregivers, recent research shows a more widespread problem: such medical abuse to spouses, the disabled, the elderly—even pets. Many involve repeat and long-term instances of hospital and medical fraud. This book covers the syndrome itself, interviewing and investigative aspects, victimology, as well indicators in the event of homicide and death.
Munchausen by Proxy: Identification, Intervention, and Case Management
by Louisa Lasher Mary S SheridanThis step-by-step guide will help you identify and manage cases of this unique form of child maltreatment! Munchausen by proxy (MBP) is a dangerous kind of maltreatment in which a caretaker deliberately and repeatedly exaggerates, fabricates, and/or induces a health problem or problems in someone under his or her care. Munchausen by Proxy: Identification, Intervention, and Case Management is the first book to walk you step-by-step through a suspected MBP maltreatment case from suspicion onward. This skills-based, practical book contains a thorough, up-to-date overview of MBP and includes suggestions for identifying and reporting to child protection agencies, investigating and gathering evidence, and legal and court procedures. Its easy readability and immediate applicability make this text a valuable tool in identifying and preventing this form of child abuse. Munchausen by Proxy is divided into three parts. The first covers the definition of MBP, the role of the perpetrator and victim, and the ethical issues affecting professionals, patients, and family. Part two addresses case work from initial suspicions through the investigative and confirmation/disconfirmation process. The third section is dedicated to case planning and case management once MBP has been confirmed, including intervention, immediate child protection, and legal activities. Those involved in a suspected or confirmed MBP case will learn about: the limits of the DSM-IV as applied to MBP perpetrator-consistent characteristics the MBP situational suspicion indicators the inappropriateness of risk assessment tools developed for other forms of maltreatment the danger when MBP perpetrators realize they are under suspicion and more! This volume is generously enhanced with case examples, sample forms, figures, and representative management plans. In Munchausen by Proxy, authors Lasher and Sheridan-experts in MBP and child protection-have come together to fill the gap in the libraries of anyone who may become involved with a MBP case. This includes child welfare professionals and staff, law enforcement, school personnel, health care practitioners, judges and lawyers, and social workers.
Mund-, Kiefer- und Gesichtschirurgie: Operationslehre und -atlas
by Harald Eufinger Alexander Kübler Henning SchliephakeIn dem Band sind alle Eingriffe der Mund-, Kiefer- und Gesichtschirurgie detailliert beschrieben und in über 1000 Zeichnungen illustriert. Darüber hinaus geben Experten der MKG-Chirurgie Tipps für die Anwendung im OP-Saal. Dargestellt werden Implantologie, septische Chirurgie, Traumatologie des Kiefer- und Gesichtsbereichs sowie die Behandlung der Lippen-Kiefer-Gaumenspalten und die Chirurgie des Gesichtsschädels, die Tumorchirurgie inklusive der plastisch rekonstruktiven Chirurgie und der modernen Verfahren des mikrovaskulären Gewebetransfers.
Munro's Statistical Methods for Health Care Research
by Stacey Plichta Elizabeth Kelvin Stacey Kellar MunroThis text provides students with a solid foundation for understanding data analysis and specific statistical techniques. Focusing on the most current and frequently used statistical methods in today's health care literature, the book covers essential material for a variety of program levels including in-depth courses beyond the basic statistics course. Well-organized, clear text discussions and great learning tools help students overcome the complexities and fully comprehend the concepts of this often intimidating area of study.
Mura Solwata Kosker: We Saltwater Women
by Ellie GaffneyThroughout her lifetime, Ellie Gaffney has been a strong advocate both within Australia and internationally of the interests and welfare of Torres Strait Islanders. She has been particularly committed to advancing the rights of Indigenous women. Her interests have spanned a wide spectrum of concerns. As an administrator, Ellie Gaffney played a significant part in the development of hostel accommodation and primary health care for all Torres Strait Islanders. Ellie's work in establishing the Mura Kosker Sorority as a platform for change is widely recognised. At all times she has been an eloquent and determined presenter of the real situation of Torres Strait Islanders. In recognition of her contribution to the Torres Strait and its people, Ellie was appointed a Member of the General Division of the Order of Australia (AM) in the Queen's Birthday Honours List. This memoir covers the period since the publication of her first book Somebody Now some twenty fours years ago. In doing so she shares with us and future generations her personal journey, a task she has undertaken at a time of failing health. It is a fitting reminder of the work and stature of a dedicated woman. Readers of this manuscript will be inspired by Ellie Gaffney's efforts on behalf of Torres Strait Islanders and all Indigenous people.
Murder & Malpractice (The Dr. Cathy Moreland Mysteries)
by Mairi ChongA doctor&’s office is plagued with deaths from unnatural causes in this &“fabulous start to a murder mystery series . . . well plotted story and great characters&” (Peter Boon, author of Who Killed Miss Finch?). Dr. Cathy Moreland has recently returned to work after battling mental health challenges, but her surgery in the British countryside is simmering, as usual, with tensions. One doctor struggles to keep up with the changes in the medical field; another, ambitious and aggressive, is romantically entangled with a nurse. The newest arrival, a pharmacist, seems very competent—but his behaviour is mysterious. When one of the doctors dies after drinking a cup of coffee, the practice is thrown into a state of suspicion and chaos. Circumstances seem to point toward one partner—but Cathy intends to examine the evidence more closely . . .
Murder By The Book: The Eighteenth Chronicle of Matthew Bartholomew (Chronicles of Matthew Bartholomew #18)
by Susanna GregoryThe eighteenth chronicle in the Matthew Bartholomew series. It is drawing near to the end of term, and the University at Cambridge is in turmoil over the opening of a new Common Library. There is an attack on one of the masters at a meeting to discuss the matter, and a body is found floating in the pond in the library's garden on the eve of its opening. Meanwhile, there are rumours of a large force of dangerous smugglers lurking in the Fens. Aided by their friend Sheriff Tulyet, Bartholomew and Michael must thwart the invaders before the Feast of Corpus Christi the following week. To fail might mean the destruction of the town...'A first-rate treat for mystery lovers' (Historical Novels Review)'Susanna Gregory has an extraordinary ability to conjure up a strong sense of time and place' (Choice)
Murder By The Book: The Eighteenth Chronicle of Matthew Bartholomew (Chronicles of Matthew Bartholomew #18)
by Susanna GregoryIt is drawing near to the end of term, and the University at Cambridge is in turmoil over the opening of a new Common Library. There is an attack on one of the masters at a meeting to discuss the matter, and a body is found floating in the pond in the library's garden on the eve of its opening. Meanwhile, there are rumours of a large force of dangerous smugglers lurking in the Fens. Aided by their friend Sheriff Tulyet, Bartholomew and Michael must thwart the invaders before the Feast of Corpus Christi the following week. To fail might mean the destruction of the town...
Murder Isn't Easy: The Forensics of Agatha Christie
by Carla ValentineFascinating - PrimaAgatha Christie is one of our most beloved authors - a storyteller unparalleled in her clever plots and twisting tales. But Agatha was also a forensic expert; in each of her books she employs an expert weaving of human observation, ingenuity and genuine science of the era.In Murder Isn't Easy Carla Valentine illuminates all of Agatha's incredible knowledge, showing how she stayed at the cutting edge of forensics from ballistics to fingerprint analysis, as seen through much-loved characters such as Poirot and Miss Marple.From the glamour and grit of Agatha Christie's stories, to the real-life cases that inspired them, Murder Isn't Easy will immerse you in the forensics that influenced generations of writers and scientists alike.
Murder Isn't Easy: The Forensics of Agatha Christie
by Carla ValentineFascinating - PrimaEngaging and informative - GuardianAgatha Christie is one of our most beloved authors - a storyteller unparalleled in her clever plots and twisting tales. But Agatha was also a forensic expert; in each of her books she employs an expert weaving of human observation, ingenuity and genuine science of the era.In Murder Isn't Easy Carla Valentine illuminates all of Agatha's incredible knowledge, showing how she stayed at the cutting edge of forensics from ballistics to fingerprint analysis, as seen through much-loved characters such as Poirot and Miss Marple.From the glamour and grit of Agatha Christie's stories, to the real-life cases that inspired them, Murder Isn't Easy will immerse you in the forensics that influenced generations of writers and scientists alike.
Murder and Madness on Trial: A Tale of True Crime from Early Modern Bologna (Interactions in the Early Modern Age)
by Mònica CalabrittoOn October 24, 1588, Paolo Barbieri murdered his wife, Isabella Caccianemici, stabbing her to death with his sword. Later, Paolo would claim to have acted in a fit of madness—but was he criminally insane or merely pretending to be? In this riveting book, Mònica Calabritto addresses this controversy by reconstructing Paolo’s life, prosecution, and medical diagnoses.Skillfully combining archival documents unearthed throughout Italy, Calabritto brings to light the case of one person and his family as insanity ravaged their financial security, honor, and reputation. The very notion of insanity is as much on trial in Paolo’s case as the defendant himself. A case study in the diagnosis of insanity in the early modern era, Barbieri’s story reveals discrepancies between medical and legal definitions of a person’s mental state at the time of a crime. Murder and Madness on Trial bridges the micro-historical dimensions of Paolo’s murder case and the macro-historical perspectives on medical and legal evidence used to identify intermittent madness.A tragic and gripping tale, Murder and Madness on Trial allows readers to look “through a glass darkly” at early modern violence, madness, criminal justice, medical and legal expertise, and the construction and circulation of news. This erudite and engaging book will appeal to early modern historians and true crime fans alike.
Murder and the Making of English CSI
by Ian Burney Neil PembertonThe engrossing account of how science-based forensics transformed the investigation of twentieth-century murders and in the process invented CSI.Crime scene investigation—or CSI—has captured the modern imagination. On television screens and in newspapers, we follow the exploits of forensic officers wearing protective suits and working behind police tape to identify and secure physical evidence for laboratory analysis. But where did this ensemble of investigative specialists and scientific techniques come from? In Murder and the Making of English CSI, Ian Burney and Neil Pemberton tell the engrossing history of how, in the first half of the twentieth century, novel routines, regulations, and techniques—from chain-of-custody procedures to the analysis of hair, blood, and fiber—fundamentally transformed the processing of murder scenes. Focusing on two iconic English investigations—the 1924 case of Emily Kaye, who was beaten and dismembered by her lover at a lonely beachfront holiday cottage, and the 1953 investigation into John Christie’s serial murders in his dingy terraced home in London’s West End—Burney and Pemberton chart the emergence of the crime scene as a new space of forensic activity. Drawing on fascinating source material ranging from how-to investigator handbooks and detective novels to crime journalism, police case reports, and courtroom transcripts, the book shows readers how, over time, the focus of murder inquiries shifted from a primarily medical and autopsy-based interest in the victim’s body to one dominated by laboratory technicians laboring over minute trace evidence. Murder and the Making of English CSI reveals the compelling and untold story of how one of the most iconic features of our present-day forensic landscape came into being. It is a must-read for forensic scientists, historians, and true crime devotees alike.
Murder by Degrees: A Mystery
by Ritu MukerjiFor fans of Jacqueline Winspear and Charles Todd, Murder by Degrees is a historical mystery set in 19th-century Philadelphia, following a pioneering woman doctor as she investigates the disappearance of a young patient who is presumed dead.Philadelphia, 1875: It is the start of term at Woman&’s Medical College of Pennsylvania. Dr. Lydia Weston, professor and anatomist, is immersed in teaching her students in the lecture hall and hospital. When the body of a patient, Anna Ward, is dredged out of the Schuylkill River, the young chambermaid&’s death is deemed a suicide. But Lydia is suspicious and she is soon brought into the police investigation. Aided by a diary filled with cryptic passages of poetry, Lydia discovers more about the young woman she thought she knew. Through her skill at the autopsy table and her clinical acumen, Lydia draws nearer the truth. Soon a terrible secret, long hidden, will be revealed. But Lydia must act quickly, before she becomes the next target of those who wished to silence Anna.
Murder by an Aristocrat (The\sarah Keate Mysteries Ser. #5)
by Mignon G EberhartAn aristocratic family hiding secrets - and murder.Classic crime from 'One of American's favourite writers' Mary Higgins Clark'Suspense to the very end' NEW YORK TIMESNurse Sarah Keate is no stranger to mystery - she has solved conspiracies and murders in places as varied as her once-sleepy hospital ward, a gothic mansion, and the Sand Hills of Nebraska. But the Thatchers are different. As close to aristocracy as an American family can get, one of their own requires Keate's care for a suspicious bullet wound to his right shoulder. A wound a relative insists was self-inflicted ...When the victim dies under even stranger circumstances, Keate knows that he was murdered. As the family closes ranks and struggles to keep its darkest secrets buried, Nurse Keate will stop at nothing to find the truth - but at what cost?
Murder in the Chilcotin (Inspector Coswell of the RCMP #3)
by Roy InnesThe third book in Roy Innes' mystery series sends RCMP Inspector Coswell and the newly promoted Sergeant Blakemore to the rugged district of West Cariboo in British Columbia, where a young Mountie constable has been found dead in his burnt-out cruiser at the bottom of a ravine. But what looks like an accident quickly reveals itself as a poorly disguised murder. With a young and ambitious Tribal Police intern as their unexpected ally, Coswell and Blakemore's investigation takes them from cattle ranches and native reserves to forests high in the hills where logging operations and marijuana grow-ops exist side by side. And all the while, the case threatens to ignite racial conflicts that have been simmering in the region for more than a century.
Murder on the Home Front: A True Story of Morgues, Murderers, and Mysteries during the London Blitz
by Molly LefebureIt is 1941. While the "war of chaos" rages in the skies above London, an unending fight against violence, murder and the criminal underworld continues on the streets below.One ordinary day, in an ordinary courtroom, forensic pathologist Dr. Keith Simpson asks a keen young journalist to be his secretary. Although the "horrors of secretarial work" don't appeal to Molly Lefebure, she's intrigued to know exactly what goes on behind a mortuary door.Capable and curious, "Miss Molly" quickly becomes indispensible to Dr. Simpson as he meticulously pursues the truth. Accompanying him from somber morgues to London's most gruesome crime scenes, Molly observes and assists as he uncovers the dark secrets that all murder victims keep.With a sharp sense of humor and a rebellious spirit, Molly tells her own remarkable true story here with warmth and wit, painting a vivid portrait of wartime London.
Murdering Animals: Writings On Theriocide, Homicide And Nonspeciesist Criminology (Palgrave Studies In Green Criminology Ser.)
by Piers BeirneMurdering Animals confronts the speciesism underlying the disparate social censures of homicide and “theriocide” (the killing of animals by humans), and as such, is a plea to take animal rights seriously. Its substantive topics include the criminal prosecution and execution of justiciable animals in early modern Europe; images of hunters put on trial by their prey in the upside-down world of the Dutch Golden Age; the artist William Hogarth’s patriotic depictions of animals in 18th Century London; and the playwright J.M. Synge’s representation of parricide in fin de siècle Ireland. Combining insights from intellectual history, the history of the fine and performing arts, and what is known about today’s invisibilised sites of animal killing, Murdering Animals inevitably asks: should theriocide be considered murder? With its strong multi- and interdisciplinary approach, this work of collaboration will appeal to scholars of social and species justice in animal studies, criminology, sociology and law.
Murderous Minds: Neurological Imaging and the Manifestation of Evil
by Dean A. HaycockIs there a biological basis for evil? From neurological imaging to behavioral studies, Dean Haycock's account of the groundbreaking research reveals what scientists are learning about the psychopaths living among us. How many times have you seen a murder on the news or on a TV show like CSI: Crime Scene Investigation, and said to yourself, "How could someone do something like that?" Today, neuroscientists are imaging, mapping, testing and dissecting the source of the worst behavior imaginable in the brains of the people who lack a conscience: psychopaths. Neuroscientist Dean Haycock examines the behavior of real life psychopaths and discusses how their actions can be explained in scientific terms, from research that literally looks inside their brains to understanding how psychopaths, without empathy but very goal-oriented, think and act the way they do. Some don’t commit crimes at all, but rather make use of their skills in the boardroom. But what does this mean for lawyers, judges, psychiatrists, victims and readers--for anyone who has ever wondered how some people can be so bad. Could your nine-year-old be a psychopath? What about your co-worker? The ability to recognize psychopaths using the scientific method has vast implications for society, and yet is still loaded with consequences. 8 page color insert
Murine Models, Energy Balance, and Cancer
by Nathan A. BergerThis volume provides a transdisciplinary and translational review of many of the leading murine models used to study the mechanisms, mediators and biomarkers linking energy balance to cancer. It provides a review of murine models that should be of interest to basic, clinical and applied research investigators as well as nutrition scientists and students that work in cancer prevention, cancer control and treatment. The worldwide obesity pandemic has been extensively studied by epidemiologic and observational studies and even, in some cases, by randomized controlled trials. However, the development and control of obesity, its comorbidities and its impact on cancer usually occurs over such long periods that it is difficult, if not impossible to conduct randomized controlled trials in humans to investigate environmental contributions to obesity, energy balance and their impact on cancer. In contrast, model organisms, especially mice and rats, provide valuable assets for performing these studies under rigorously controlled conditions and in sufficient numbers to provide statistically significant results. In this volume, many of the leading and new murine models used to study the mechanisms and mediators linking cancer with obesity, sleep, exercise, their modification by environment and how they may continue to be used to further elucidate these relations as well as to explore preclinical aspects of prevention and/or therapeutic intervention are considered. This volume provides an important compilation and analysis of major experimental systems and principles for further preclinical research with translational impact on energy balance and cancer.