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Neurochirurgische Therapie des Schädel-Hirn-Traumas
by Alexander König Uwe SpetzgerDas neurochirurgische Vorgehen bei Schädel-Hirn-Traumata wird detailliert und reich illustriert beschrieben: von der präklinischen und klinischen Erstversorgung über die indikationsspezifische Bildgebung bis zur Nachsorge und den Grundzügen der neurologischen Rehabilitation. Im Mittelpunkt steht die operative Versorgung des akuten Traumas, die für die typischen Verletzungsmuster Schritt für Schritt mit zahlreichen Illustrationen dargestellt wird. Zusätzlich gehen die Autoren auf die verschiedenen Formen der Kranioplastik zur Deckung des Kalottendefektes ein. Grundlage der Darstellung ist die umfassende Expertise der Autoren aus einem zertifizierten Traumazentrum.
Neurochirurgische Therapie von Verletzungen der Halswirbelsäule: Grundlagen, Indikationsstellung, chirurgische Techniken
by Alexander König Torsten Roediger Uwe SpetzgerDas Buch vermittelt zunächst anatomische und biomechanische Grundlagen sowie die gängigen Klassifikationen von Verletzungen der Halswirbelsäule, letztere an konkreten klinischen Beispielen mit umfangreicher Bebilderung. Danach werden präklinische sowie frühe klinische Behandlung von Patienten mit einem Halswirbelsäulentrauma erörtert. Anhand der Ergebnisse der initialen Diagnostik erfolgt die Indikationsstellung zur Operation bei allen instabilen Verletzungen einschließlich der Wahl des operativen Verfahrens. Schwerpunkt des Buches ist die ausführliche Darstellung der einzelnen chirurgischen Techniken: ventrale Versorgung mit Diskus- und Wirbelkörperersatz plus ventraler Plattenosteosynthese sowie dorsale Versorgung mit Fixateur interne. Ein ausführliches Unterkapitel wird der spinalen Navigation als moderne Hilfstechnik bei Wirbelsäuleninstrumentierungen gewidmet. Neben der fotografischen Darstellung der einzelnen chirurgischen Teilschritte sind auch immer wieder klinische Beispiele eingefügt. Den Abschluss bilden Ausführungen zur Rehabilitation von wirbelsäulenverletzten Patienten.
Neurocinema: When Film Meets Neurology
by Eelco WijdicksFilm directors recognize that neurologic disease impacts mind and motility and often use it in a plot or defining scene. It should be informative and educational to deconstruct neurologic representation in film. Neurocinema: When Film Meets Neurology is a collection of film essays that summarize the portrayal of major neurologic syndromes and clinical signs in cinema. Many films approach the reality of disease quite closely, and as a result, are deeply moving and memorable. Equally important, these films say as much about consequences as they say about the disorder. Therefore, the main themes include sudden confrontation with a major neurologic illness, disability from chronic neurologic disease, and failure to lead a normal life. <P><P>More than 100 fiction films and documentaries are discussed in this completely original and definitive work on how film meets neurology. The book includes nearly 50 neurology topics, explains them, and places them in a broader context. The book is accessible for all health care workers and general readership.
Neurocinema—The Sequel: A History of Neurology on Screen
by Eelco F. WijdicksThe history of neurology as seen through the lens of the filmmaker is fascinating and extraordinary. Neurocinema-The Sequel is a review of the history of neurology as seen in film, starting with the early days of cinema and concluding with contemporary films now available in theaters and on streaming sites. The major themes of this book encompass how neurology has been represented in the history of cinema and how neurologic topics emerged and then disappeared, with some staging a comeback in more recent films. 180 films are assessed and rated, and many of these are exemplary depictions of neurological disorders. The author examines whether film, from a neurologic perspective, can provide insight and even debate. Each of the films discussed in this book demands serious attention by those who see and manage neurologic patients and support their families. Neurocinema - The Sequel chronicles this archive of neurologic representation, drawing readers in a rich collection of cinematic wonders of permanent cultural and historical value.
Neurocognitive Behavioral Disorders: An Interdisciplinary Approach to Patient-Centered Care
by Maureen Nash Sarah FoidelDementia, now known as major neurocognitive disorder, is not one monolithic disease. Nor is behavior disturbance driven by one particular neurocognitive dysfunction. In fact if we are able to understand it, behavior is an excellent form of nonverbal communication. There are many different causes of dementia. A major challenge with both researching and implementing interventions is viewing dementia and related behaviors as single entities. This approach leaves room for critical errors in the treatment of dementia patients, beginning with misdiagnosis. This book approaches dementia by reviewing cognitive and functional assessments to provide a more accurate diagnosis, which then allows physicians to design specific interventions that are tailored to the person and their challenges. Because person centered care is vital to quality of life and longevity to an aging patient, this understanding of individual needs is vital. Written by experts in the field, this book incorporates the latest evidence-based behavioral interventions matched to specific deficits. Behavioral management focuses not on controlling behavior, but using it to teach staff and caregivers how to interpret common actions and maximize function for people with major neurocognitive disorders. Quality of life and individualized care planning will be the theme and the book will provide practical case examples. The book begins by introducing dementia and other neurocognitive illnesses, contextualizing them both historically and contemporarily. Next, the text focuses on the comprehensive assessment of a person with neurocognitive challenges in order to identify strengths and understand what the person is trying to communicate with their behavior. This process allows individualized care planning and behavioral (non-pharmacologic) management to meet the cognitive challenges and maximize individual strengths and thereby improve outcomes, making this a cutting edge resource.
Neurocognitive Complications of HIV-Infection: Neuropathogenesis to Implications for Clinical Practice (Current Topics in Behavioral Neurosciences #50)
by Lucette A. Cysique Sean B. RourkeThis volume aims at presenting the latest international research and discoveries in the neurocognitive aspects and complications in HIV/AIDS, and how this understanding can shape and inform how we think about clinical practice and patient care in HIV/AIDS as well as lead to a better understanding of the underlying neuropathogenesis.The chapter, "Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders", of this book is available open access under a CC BY 4.0 license at link.springer.com
Neurocognitive Music Therapy: Intersecting Music, Medicine and Technology for Health and Well-Being
by Rafael Ramírez-MeléndezFor thousands of years, music has acted as a powerful medium for evoking emotions, facilitating communication, and nurturing overall well-being. With the advent of new sophisticated neuroimaging technology, human responses to music and music therapy are being viewed through a new lens. As a consequence, new knowledge is being obtained about how music can produce significant improvements in cognitive, social, overt and agitated behaviours. The aim of this book is to provide an overview of neurocognitive music therapy, its impact and implications in the practice of evidence-based music interventions. The book seeks to provide researchers, psychologists, music therapists, musicians and physicians interested in the therapeutic applications of music, with a source of information about current techniques and novel music interventions. It is structured into several chapters, each of them presenting peer-reviewed research and evidence-based procedures carried out in a specific clinical context. Topics covered in the book include: Musical engagement for individuals with motor disabilities Enhancing emotional processing in autism through music Stroke rehabilitation via musical interventions Musical neurofeedback for emotional disorders Emotional modulation with music therapy in palliative care AI-driven personalisation in music interventionsThe book highlights the profound capacity of music-based interventions to facilitate cognitive and emotional processing, enhance communication, and promote motor rehabilitation. At the same time, the book demonstrates how modern technologies offer new opportunities to evaluate, validate, and potentiate music-based interventions, allowing new and innovative possibilities and more personalised interventions. This book aims to contribute to the growing body of knowledge in this field and inspire further research and innovation in the practice of music therapy.
Neurocritical Care
by Kosaku KinoshitaThis book discusses the factors that affect outcomes in patients requiring various types of neurocritical care. Neurocritical care was originally developed to manage patients with traumatic brain injury or stroke. Today, neurocritical care involves patients with a wide variety conditions, including not only brain injury, cerebrovascular disease and brain tumors but also post cardiac arrest syndrome, metabolic disorders, sepsis-related encephalopathy, degenerative diseases, and electrolyte abnormalities. Recently, there has been a focus on improving the outcomes and patients’ quality of life. Covering the latest topics in the field, and written by specialists such as neurosurgeons, anesthesiologists and neurologists, the book provides an update on therapeutic / management strategies for disorders requiring neurocritical care for emergency physicians, intensivists and critical care physicians.
Neurocritical Care
by Justin Mckinlay John P. Adams Dominic BellTraumatic brain injury is the leading cause of death in young people in the UK and USA. The vast majority of these patients will be initially managed outside the teaching hospital environment and many will remain there for the duration of their treatment. As clinicians, what happens during the first hours and days after injury can have a huge influence on the patient's chance of survival and also their quality of life after the injury. Results of a recent national survey have highlighted 2 main areas of major concern. Firstly, there are far too few specialist neurosurgical beds in out tertiary referral centers, which means that District General Hospital Intensive Care Units are frequently having to manage very seriously brain injured patients. Secondly, many clinicians do not know when they should be speaking to their Regional Neurosurgical Centre, do not fully understand how they should be managing these patients, do not know how to interpret the relevant physiological and radiological data, and have difficulty identifying when to escalate treatment and when the situation has become futile. Lives could therefore be saved and outcomes improved with the introduction of common treatment pathways and better defined lines of communication between referring hospitals and specialist centers.
Neurocritical Care (Cambridge Manuals in Neurology)
by Andrew M. NaidechEvents in a neurological intensive care unit are not always predictable and patients can often be unstable. This practical manual is a clear and concise guide for recognising and managing neurological emergencies. Each chapter covers a crucial topic in neurocritical care, from understanding the pathophysiology of various neurological diseases, to neuroradiology used in diagnosis, and best practice for difficult decision making in the ICU. A variety of conditions are described such as haemorrhage (intracerebral, subdural, and subarachnoid), seizures, trauma and temperature dysregulation. An international team of experts have contributed chapters, providing a breadth of experience and knowledge for readers. This is an invaluable guide for clinicians on the front line of caring for patients with neurological emergencies who need life-saving answers quickly.
Neurocritical Care
by Michel T. TorbeyA significant number of critically ill neurological and neurosurgical patients are still managed in the medical or surgical ICU by non-neurointensivists, who have a hard time appreciating the delicate needs of these patients. This dynamic guide reviews current topics facing neurocritical care providers in a straight-forward, structured, and practical way. Providing clear summaries in the management of neuro critical care conditions, this text allows for accessible, highly structured, and focused protocols for the assessment, day-to-day management, and treatment of critically ill patients in various ICU settings. This comprehensive, thorough guide to the management and treatment of neurologic and neurosurgical patients, is an excellent companion for trainees preparing for the Neurovascular Boards, Neurologists, Neurosurgeons and critical care physicians, alike. Designed by leaders in their field, this thorough guide presents practical, state-of-the-art suggestions for physicians, worldwide.
Neurocritical Care
by Michel T. TorbeyEditor Torbey (neurology and neurosurgery, Medical College of Wisconsin) and 57 contributors provide a reference for physicians who work with critically ill and neurosurgical patients. Specifically, it is intended for those physicians who are not neurologists but who must treat patients in medical or surgical intensive care units--and offers guidance in management and treatment for those physicians. The authors address the principles of neurocritical care, management of specific disorders in the neurocritical care unit, neuromonitoring, and management of medical disorders. The book is very well written and formatted. Chapters include extensive references and illustrations are clear and nicely explained. Annotation ©2010 Book News, Inc. , Portland, OR (booknews. com)
Neurocritical Care Essentials: A Practical Guide
by Mypinder S. Sekhon Donald E. Griesdale MPHThis practical new resource uses a highly visual approach to summarise and simplify neurocritical care topics which can often seem daunting in their complexity. Diagrams, flowcharts, figures and tables highlight the main principles of disease pathophysiology, diagnosis and management, giving an easy-to-understand insight into this new and exciting field of medicine. Numerous high-quality radiographic images demonstrate the neuroimaging of neurological and neurosurgical diseases, and overviews of major clinical trials and studies provide an evidence-based perspective. Incorporating a full grounding in the fundamentals of neuroanatomy, neurophysiology and examination, and summaries of key points and suggested reading for each chapter, this book is a concise yet thorough reference for all those working in neurocritical care. Ideal for both trainees and specialists in neurology, neurosurgery, intensive care, anaesthesiology, emergency medicine and internal medicine.
Neurocritical Care for Neurosurgeons: Principles and Applications
by Eberval Gadelha Figueiredo Leonardo C. Welling Nícollas Nunes RabeloThis unique book discusses the management of neurocritical care patients, including basic concepts, pathophysiologic principles, monitoring, treatment indications, and factors that affect outcomes in patients requiring neurocritical care assistance. It addresses the need to improve continuing education in this area, highlighting patient care in the perioperative period. This is the first book to provide a simplified overview for neurosurgeons and neurologists to understand the neurocritical patient journey. It is divided into three parts: the first covers the basics concepts, from monitoring to the interpretation of exams; the second explores general management of specific situations encountered in intensive care and the last part includes prognostic and rehabilitation models, as well as new perspectives. Thanks to the accessible, neurosurgical specific language, the book is well suited for all professionals involved in neurocritical care, including students, but is also a valuable resource for residents and researches, as well as experienced neurosurgeons or neurologists looking for updated information and guidelines.
Neurocritical Care for the Advanced Practice Clinician
by Jessica L. White Kevin N. ShethBy utilizing a review of case-based studies and providing concise management recommendations from leaders in the field, this book provides essential knowledge for those practicing in a dynamic specialty. In the rapidly developing field of Neurocritical Care, Advanced Practice Clinicians have become an integral component of the multi-disciplinary team. This essential volume provides a frame of reference for advanced practice nurses, physician assistants, physicians, and students on a wide range of common Neuro ICU diagnoses and management strategies.
Neurocritical Care Informatics: Translating Raw Data into Bedside Action
by Michael De Georgia Kenneth LoparoHealth care in the twenty-first century requires intensive use of technology in order to acquire and analyze data and manage and disseminate information. No area is more data intensive than the neurointensive care unit. Despite the massive amount of data, however, providers often lack interpretable and actionable information. This book reviews the concepts underlying the emerging field of neurocritical care informatics, with a focus on integrated data acquisition, linear and nonlinear processing, and innovative visualization in the ICU. Subjects addressed in individual chapters are thus wide ranging and encompassing, for example, multimodal and continuous EEG monitoring and data integration, display of data in the ICU, patient-centered clinical decision support, optimization of collaboration and workflow, and progress towards an “integrated medical environment”. All of the nine chapters have been written by international thought leaders in the field.
Neurocutaneous Disorders: A Clinical, Diagnostic and Therapeutic Approach
by Christos P. Panteliadis Ramsis Benjamin Christian HagelThis book provides extensive data on the more common and many of the more rare congenital and hereditary syndromes that manifest in the nervous system and skin. Though often complex and multi-systemic, these disorders can frequently be diagnosed using a combination of simple visual inspection and sound clinical expertise. Drawing on fully referenced information from thousands of articles, the international editorial team has prepared a comprehensive overview that includes historical perspectives, clinical features, the pathogenesis, and diagnostic and therapeutic strategies. In addition, it addresses the biochemical, molecular, and genetic basis of the disorders. The book is divided into four main sections. Starting with general aspects of aetiology, diagnostics and therapy, the first part then covers the genetics, neuro-imaging, neuropathology, ocular manifestations and surgical management. The second part discusses developmental malformations, such as Sturge-Weber syndrome, Ataxia-Telangiectasia, Hypomelanosis of Ito and other rare syndromes, including haemangiomas. The focus of the third part is on tumour suppressor/DNA repair disorders, the most common of which is Neurofibromatosis 1. It also describes Neurofibromatosis 2, Schwannomatosis, Tuberous sclerosis, von Hippel-Lindau disease, Naevoid basal cell carcinoma and others. The book’s fourth and final section covers defects in enzymes and structural proteins, which manifest as Cerebrotendinous xanthromatosis, Ehlers-Danlos syndrome, Menkes syndrome, Refsum disease.
Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders (Second Edition)
by Dennis Dickson Roy O. WellerMost textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology. In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries. Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within cells (e.g. tau, α-synuclein and TDP-43) and in the extracellular compartments (e.g. β-amyloid and prion proteins) or according to a shared pathogenetic mechanism, such as trinucleotide repeats, that are a feature of specific genetic disorders. Chapters throughout the book conform to a standard lay-out for ease of access by the reader and are written by a panel of International Experts Since the first edition of this book, major advances have been made in the discovery of common molecular mechanisms between many neurodegenerative diseases most notably in the frontotemporal lobar degenerations (FTLD) and motor neuron disease or amyotrophic lateral sclerosis. This book will be essential reading for clinicians, neuropathologists and basic neuroscientists who require the firm up-to-date knowledge of mechanisms, diagnostic pathology and genetics of Neurodegenerative diseases that is required for progress in therapy and management.
Neurodegeneration
by Institute of Medicine Board on Health Sciences Policy Miriam Davis Forum on Neuroscience and Nervous System Disorders Clare StroudNeurodegeneration: Exploring Commonalities Across Diseases is the summary of a workshop hosted by the Institute of Medicine\'s (IOM\'s) Forum on Neuroscience and Nervous System Disorders in Spring 2012 to explore commonalities across neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD). Participants from academia; pharmaceutical and biotechnology industries; government agencies such as the National Institutes of Health and the U.S. Department of Veterans Affairs (VA); patient advocacy groups; and private foundations presented and identified potential opportunities for collaboration across the respective research and development communities. This report identifies and discusses commonalities related to genetic and cellular mechanisms, identifies areas of fundamental science needed to facilitate therapeutics development, and explores areas of potential collaboration among the respective research communities. Neurodegenerative diseases, such as Alzheimer\'s disease, Parkinson\'s disease, ALS, and FTD, are becoming increasingly prevalent in the United States due to an aging population. Implications are grave for quality of life and health care costs. Research on neurodegenerative diseases has expanded greatly over the past four decades. Nevertheless, fundamental questions remain about the biology of these diseases, and further insights into the mechanisms of these diseases would help to inform the development of effective means to prevent and to efficiently treat them. Recent findings have revealed certain commonalities in genetic and cellular mechanisms across neurodegenerative diseases. These findings suggest that it might be valuable - at least in some cases - to change the traditional way of studying these diseases by no longer seeing each as an independent entity, but rather as clinical variants of common cellular and molecular biological defects. This approach could help enhance basic scientific understanding of neurodegenerative disease, and could help with the development of biomarkers and new therapeutics.
Neurodegeneration
by Giovanni Manfredi Hibiki KawamataNeurodegenerative disorders, such as Alzheimer's and Parkinson's disease are a growing burden on our society. Understanding and treating these common diseases is one of the major current challenges for the biomedical field. In Neurodegeneration: Methods and Protocols, experts in the field tackle this challenge and present cutting-edge analytical and technological approaches to study the mechanisms underlying neurodegenerative processes. Organizes into five sections, chapters detail protocols for isolating and culturing cells from the nervous system, production and use of animal models, characterization of cell death, analytical tools to study disease mechanisms, and therapeutic approaches for neurodegeneration. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Neurodegeneration: Methods and Protocols serves as an ideal guide to both novice and professional researchers in the field of neurodegeneration.
Neurodegeneration
by Anthony Schapira Nicholas Wood Ted M. Dawson Zbigniew K. WszolekThis book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject. Presents a clinically oriented guide to the diseases caused by neurodegeneration Templated chapters combine clinical and research information on neurodegenerative diseases beginning with the common elements before treating each disease individually Diseases are grouped by anatomical regions of degeneration and include common disorders such as Parkinson's Disease, Alzheimer's Disease, Amyotrophic Lateral Sclerosis/Motor Neuron Disease, and Multiple Sclerosis as well as less common diseases Edited by globally leading authorities on the subject, and written by expert contributing authors
Neurodegeneration – 35 Fallbeispiele aus der Praxis
by Anne-Sophie Biesalski Lars TöngesDieses Buch bietet 35 klinische Kasuistiken, die unterschiedliche Symptomatiken, Patientengruppen und Verläufe bei neurodegenerativen Erkrankungen darstellen. Eine Erkrankungsgruppe, die sich sehr heterogen präsentiert und in Diagnose und Therapie gerade für den Anfänger in der neurologischen Weiterbildung komplexe Fallstricke bereithalten kann. Die Fälle sind klar und einheitlich gegliedert. Relevante Informationen zu einer Erkrankung wurden komprimiert zusammengefasst, ergänzt durch Hinweise auf hilfreiche Zusatzthemen wie den Umgang mit Erkrankten oder Tipps zur Diagnose- und Prognosevermittlung. Die Fallgeschichten werden leitliniengerecht besprochen und orientieren sich an etablierten SOPs (Standard Operating Procedures) der Neurologie. Vertiefende Multiple-Choice-Fragen zum Selbstlernen sind über die Springer Flashcards-App zugänglich und regen zum klinischen Nach- und Mitdenken an.
Neurodegeneration Methods and Protocols
by Hugh A. Tilson Jean HarryAn outstanding collection of detailed, state-of-the-art techniques for studying many aspects of nervous system cell biology. The methods span a multidisciplinary range of cellular and molecular approaches to both normal and injured nervous system function, and particularly to neurodegenerative processes. Included are basic RT-PCR techniques, cell culture systems, second-messenger signaling methods, and patch-clamp techniques. These powerful techniques will illuminate nervous system function, injury, degeneration, and the repair/regenerative process.
Neurodegenerative Diseases
by Celia DominguezThe Role of Histone Deacetylases in Neurodegenerative Diseases and Small-Molecule Inhibitors as a Potential Therapeutic Approach.- Phosphodiesterase Inhibition to Target the Synaptic Dysfunction in Alzheimer's Disease.- Glutamate and Neurodegenerative Disease.- Modulation of the Kynurenine Pathway for the Potential Treatment of Neurodegenerative Diseases.- Spinal Muscular Atrophy: Current Therapeutic Strategies
Neurodegenerative Diseases
by Daniela Galimberti Elio ScarpiniThis book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases. Different aspects of each disease are reviewed, including clinical issues, treatments, basic discoveries (genetics and molecular biology), and translation of basic research into biomarkers for early diagnosis. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis. Neurodegenerative Diseases is aimed at clinicians, particularly those working in academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields.