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Neuropsychiatric Disorders

by Kiyoshi Maeda Yasushi Morimura Koho Miyoshi

Around the world societies are facing growing aging populations with the concomitant increase in neuropsychiatric disorders. Neuropsychiatric disorders are organic brain diseases with psychiatric symptoms, as in Alzheimer's and Parkinson's diseases, that cause cognitive impairment, including dementia, amnesic syndrome, and personality-behavioral changes. As a clinical science, neuropsychiatry aims to explore the complex interrelationship between behavior and brain function from a variety of perspectives, including those of psychology, neurology, and psychiatry. This concise and updated monograph comprises the latest findings in the field and includes chapters on delusional symptoms, mood disorders and neurotic symptoms, cognitive impairment, behavioral and personality changes, and recently, cerebral alterations revealed in PTSD patients and in endogenous psychoses through neuroimaging and neuropathology. These findings will certainly widen the realm of neuropsychiatry going forward and will prove of great value to specialists as well as to academics and trainees in neurology, psychiatry, neuropsychology, neuroradiology, neuropathology, neurophysiology, neurochemistry, and clinical genetics. Ultimately, neuropsychiatry aims to prevent and reduce the suffering of individuals with the psychiatric symptoms of cerebral disorders.

Neuropsychiatric Dysfunction in Multiple Sclerosis

by Gioacchino Tedeschi Ugo Nocentini Carlo Caltagirone

This book provides comprehensive and up-to-date information on the neuropsychiatric disturbances that may be experienced by patients with multiple sclerosis. The first section is designed primarily to describe the general clinical aspects of multiple sclerosis, from epidemiology to assessment tools. The role of neuroimaging and especially MRI is then explained, and treatment approaches and rehabilitation strategies are described. The core section of the volume is the second, in which the various forms of neuropsychiatric dysfunction are considered in depth. Especially, detailed attention is devoted to depression, but the other main categories of disturbance are also described and discussed. The final section addresses cognitive dysfunctions since they represent some of the worst events that patients with multiple sclerosis can suffer and are intimately related to neuropsychiatric dysfunction.

Neuropsychiatric Manifestations in Neurological Diseases

by Jong S. Kim

Psychiatric symptoms (or mood/emotional disturbances) are diverse in patients with neurological diseases, that include depression, anxiety, emotional incontinence, anger, fatigue, and apathy. These symptoms are common; more than 1/3 of the patients suffer from these symptoms. Unfortunately, they have been neglected because 1) unlike other neurological symptoms such as motor dysfunction, speech disturbances or visual field defect, these symptoms are not visible and difficult to be noticed unless they are specifically examined by a physician who is properly educated on this problem 2) they are often not regarded as neurological symptoms either by the patients or their caregivers 3) they are relatively poorly studied by both neurologists and psychiatrists, and accordingly, are unfamiliar to the physicians. Especially, although `depression’ is well known to physicians, other symptoms such as emotional incontinence, anger, fatigue or apathy are not appropriately assessed by physicians, and frequently misdiagnosed as depression. Moreover, there are difficulties in diagnosing depression in patients neurological diseases. For example, the individual items included in depression diagnosis such as sleep disturbances, appetite loss, or fatigue can result from neurological diseases or comorbid physical conditions in patients with neurological diseases. Therefore, a diagnosis of `depression’ should be made cautiously. Finally, it should be understood that the importance of different mood/ emotional syndromes differ among various neurological diseases; for instance, although emotional incontinence and anger occur in as many as 20-30 % of stroke patients, apathy and fatigue are more important symptoms than these for patients with neuro-degenerative disease.In clinical practice, recognizing these symptoms is important because they negatively affect the patients’ quality of life, impair the functional recovery, increase the mortality, and increase the caregiver burden. Nevertheless, unlike other neurological symptoms such as motor/sensory dysfunction, and speech disturbances, they are relatively well managed mostly by pharmacological therapy such as selective serotonin re-uptake inhibitors (SSRI).The phenomenology of these neuropsychiatric symptoms and related factors, pathophysiological mechanism, and treatment strategies should be properly educated for neurologists, psychiatrists and other physicians. The book is written by experts in this field to disseminate important knowledges to neurologists, psychiatrists, psychologists and other physicians and will eventually benefit patients with neurological diseases.

Neuropsychiatric Symptoms of Cerebrovascular Diseases

by José M. Ferro

Neuropsychiatric Symptoms of Cerebrovascular Diseases is an up-to-date, comprehensive review of the neuropsychiatry of stroke, by active authorities in the field, with an emphasis on diagnostic and management issues. Neuropsychiatric Symptoms of Cerebrovascular Diseases includes critical appraisal of the methodological aspects and limitations of the current research on the neuropsychiatry of stroke and on unanswered questions/controversies. Pharmacological aspects of management are discussed, to provide robust information on drug dosages, side effects and interaction, in order to enable the reader to manage these patients more safely. Illustrative cases provide real life scenarios that are clinically relevant and engaging to read. Neuropsychiatric Symptoms of Cerebrovascular Diseases is aimed at neurologists, stroke physicians and psychiatrists, and will also be of interest to intensive care doctors, psychologists ad neuropsychologists, research and specialist nurses, clinical researchers and methodologists.

Neuropsychiatric Symptoms of Cognitive Impairment and Dementia

by Ana Verdelho Manuel Gonçalves-Pereira

This book is an up-to-date, comprehensive review of the neuropsychiatry of different types of cognitive impairment by active authorities in the field. There is an emphasis on diagnostic and management issues. Cognitive impairment both with and without criteria for dementia is covered. A critical appraisal of the methodological aspects and limitations of the current research on the neuropsychiatry of cognitive impairment and dementia is included. Unanswered questions and controversies are addressed. Non-pharmacological and pharmacological aspects of management are discussed, to provide robust information on drug dosages, side effects and interaction, in order to enable the reader to manage these patients more safely. Illustrative cases provide real life scenarios that are clinically relevant and engaging to read. Neuropsychiatric Symptoms of Cognitive Impairment and Dementia is aimed at neurologists, psychiatrists, gerontologists, and general physicians. It will also be of interest to intensive care doctors, psychologists and neuropsychologists, research and specialist nurses, clinical researchers and methodologists.

Neuropsychiatric Symptoms of Epilepsy

by Marco Mula

This book is an up-to-date, comprehensive review of the neuropsychiatry of epilepsy, by active authorities in the field, with an emphasis on clinical and management issues. A critical appraisal of the methodology and limitations of current research on the neuropsychiatry of epilepsy is provided, and unanswered questions and controversies are addressed. Pharmacological aspects of management are also discussed in order to enable the reader to manage these patients more safely. Neuropsychiatric Symptoms of Epilepsy is aimed at neurologists, epileptologists, psychiatrists and neuropsychiatrists, and will also be of interest to psychologists and neuropsychologists, research and specialist nurses, clinical researchers and methodologists.

Neuropsychiatric Symptoms of Inflammatory Demyelinating Diseases

by Bruno Brochet

This book is an up-to-date, comprehensive review of the neuropsychiatry of multiple sclerosis and related diseases, by active authorities in the field, with an emphasis on diagnosis and management. Critical appraisal of the methodological aspects and limitations of the current research on the neuropsychiatry of demyelinating diseases is included, and unanswered questions are highlighted. Pharmacological aspects of management are discussed. Neuropsychiatric Symptoms of Inflammatory Demyelinating Diseases is aimed at neurologists, multiple sclerosis specialists and psychiatrists, and will also be of interest to intensive care doctors, psychologists ad neuropsychologists, research and specialist nurses, clinical researchers and methodologists.

Neuropsychiatric Symptoms of Movement Disorders

by Heinz Reichmann

This is an up-to-date, comprehensive review of the neuropsychiatry of patients with movement disorders, i. e. Parkinson's disease, Huntington's disease, dystonia and others, by active authorities in the field, with an emphasis on diagnostic and management issues. This book includes critical appraisal of the methodological aspects and limitations of the current research on the neuropsychiatry of movement disorders and on unanswered questions/controversies. Symptomatology and pharmacological aspects of management are discussed, to provide robust information on drug dosages, side effects and interaction, in order to enable the reader to manage these patients more safely. Illustrative cases provide real life scenarios that are clinically relevant and engaging to read. Neuropsychiatric Symptoms of Movement Disorders is aimed at neurologists, movement disorder specialists and psychiatrists and will also be of interest to intensive care doctors, psychologists and neuropsychologists, research and specialist nurses, clinical researchers and methodologists.

Neuropsychiatric Systemic Lupus Erythematosus: Pathogenesis, Clinical Aspects And Treatment

by Shunsei Hirohata

Neuropsychiatric manifestation in systemic lupus erythematosus (NPSLE) is one of the most recalcitrant complications of the disease. According to the 1999 ACR nomenclature and case definitions, diffuse psychiatric/neuropsychological syndromes in NPSLE (anxiety disorder, acute confusional state, cognitive dysfunction, mood disorder, psychosis) (diffuse NPSLE) present psychiatric manifestations unlike neurologic syndromes (focal NPSLE) originating from focal CNS lesions, such as cerebrovascular disease, demyelinating syndrome, headache, aseptic meningitis, chorea, seizures and myelopathy. A number of studies have reported that diffuse NPSLE is usually associated with the presence of autoantibodies against neuronal cells in serum as well as in cerebrospinal fluid (CSF). Moreover, IL-6 has been shown to be elevated in CSF of patients with diffuse NPSLE.Recently, it has been demonstrated that the severity of blood-brain barrier damages plays a crucial role in the development of acute confusional state, the severest form of diffuse NPSLE through the accelerated entry of larger amounts of autoantibodies to NMDA receptor subunit NR2 into the CNS. Since the importance of autoantibodies in the NPSLE has been now evident, such an aggressive treatment, especially B cell depleting therapy, would make sense in that it would reduce the levels of pathogenic autoantibodies, leading to a better prognosis of NPSLE.As far as we know, no single book specifically dedicated to NPSLE alone has been published as yet. As mentioned above, NPSLE constitutes a vastly expanding field of research with increasing numbers of papers published annually. Therefore, we believe that an effort to collect and critically review these publications is invaluable. Such an effort will provide an important contribution to basic researchers as well as clinicians working in the field of neurology, rheumatology, psychiatry and internal medicine fields.

Neuropsychiatry Case Studies

by Josef Priller Hugh Rickards

This book comprises succinct, accessible clinical cases in neuropsychiatry. Each clinical case has a specific and practical learning point, concerned with assessment, diagnosis, treatment or general approach. Each case models clinical reasoning and shows how the 'puzzle' in the case changed the future practice of the author. Neuropsychiatry Case Studies is divided into sections relating to specific areas of neuropsychiatry, including dementias, movement disorders, autoimmune encephalopathies and epilepsy, amongst others. This book is aimed at trainee doctors in neurology and psychiatry and will also be of interest to fully trained doctors, nurses, psychologists and other allied health professionals working in this area. ​

The Neuropsychiatry of Epilepsy

by Bettina Schmitz Michael R. Trimble

Research into the neuropsychiatry of epilepsy has become a central focus of interest in the last five years. Comorbidity of epilepsy with behavioral problems is now recognized widely, and the neuroscientific basis for such comorbidity is an active area of investigation. With an expanded international team of authors, this fully revised new edition builds on the strengths of its predecessor, examining in detail the subtleties of behavioral changes in patients with seizure disorders and offering both a diagnostic and a management perspective. New chapters cover genetic disorders, the effects of epilepsy on social behavior as viewed through theory of mind, a discussion of the precuneus, the importance and nature of peri-ictal psychiatric symptoms, depression and the interictal dysphoric disorder, and the relationship between antiepileptic drugs and suicide. This new edition is a must for anyone involved in diagnosing or managing epilepsy.

The Neuropsychiatry of Headache

by Mark W. Green Philip R. Muskin

Whilst the vast majority of headaches are minor ailments, some patients develop chronic symptoms that have psychiatric dimensions. These symptoms can be immensely challenging to manage and can have a serious impact on the patient's quality of life. The relationship between headache and psychiatric disease is often rationalized as cause and effect; however, the interplay between the two is complex. Management of each of the co-morbid disorders affects the other one in positive and/or negative ways. The Neuropsychiatry of Headache details the current concepts of various headache conditions and the psychiatric syndromes; topics covered include migraine, mood disorders, medication overuse and personality disorders. Headache specialists, neurologists, psychiatrists, neuropsychiatrists and neuropsychologists will find this an invaluable resource for understanding and co-managing these conditions.

Neuropsychoanalyse: Eine Einführung in Neurowissenschaft und psychodynamische Therapie (essentials)

by Gerd Thomas Waldhauser

Neurowissenschaft und Psychoanalyse erscheinen zunächst als zwei grundsätzlich verschiedene, unvereinbare Zugänge zum menschlichen Erleben und Verhalten. Allerdings gab es schon seit Beginn der Entwicklung der Psychoanalyse immer wieder Bestrebungen, psychoanalytische Konzepte und Prozesse neurowissenschaftlich zu begründen. Auf der anderen Seite liefert die Psychoanalyse ein umfassendes Modell der menschlichen Psyche in all ihrer Komplexität und Dynamik, welches helfen könnte, die vielfältigen und häufig sehr spezialisierten Ergebnisse der modernen Hirnforschung in ihrer Gesamtheit zu verstehen. Das vorliegende Buch fasst den momentanen Stand der Forschung in diesem Schnittbereich zwischen Tiefenpsychologie und Hirnforschung zusammen und arbeitet heraus, wie sowohl Praktiker als auch Grundlagenforscher von einem fruchtbaren Austausch zwischen den beiden Disziplinen profitieren können.

Neuropsychoanalysis: An Introduction to Neuroscience and Psychodynamic Therapy (essentials)

by Gerd Thomas Waldhauser

Neuroscience and psychoanalysis initially appear as two fundamentally different, incompatible approaches to human experience and behavior. However, from the very beginning of the development of psychoanalysis, there have been repeated efforts to ground psychoanalytic concepts and processes in neuroscience. On the other hand, psychoanalysis provides a comprehensive model of the human psyche in all its complexity and dynamics, which could help to understand the diverse and often highly specialized findings of modern brain research in their entirety. This book summarizes the current state of research in this area of intersection between depth psychology and brain research and elaborates how both practitioners and basic researchers can benefit from a fruitful exchange between the two disciplines.

Neuropsychodynamic Psychiatry

by Heinz Boeker Peter Hartwich Georg Northoff

This book presents a comprehensive neuropsychodynamic strategy for treating psychiatric disorders. Rather than pursuing an exclusively biological, psychological, or psychodynamic approach, it offers a methodology that links all three aspects in a unifying, integrative model. Central to this approach is the view of the brain as a bio-psychosocial organ in a neuro-ecological model, rather than the purely neuronal model often presupposed in current neuroscience and psychiatry. Moreover, the book views psychopathological symptoms as spatiotemporal disorders of the altered spatiotemporal structure spanning the brain and its surrounding world. The relation between one of the core symptoms and altered neuronal activity calls for the development of integrated, circular neuropsychodynamic models of psychopathological symptoms in severe psychiatric disorders and their treatment.

The Neuropsychological Analysis of Problem Solving

by Luria

For any of us, problem solving is a daily event. For some, it is a major task. This historical book puts to use neuropsychological methods to analyze the process of problem solving. Experience shows that the process is psychologically so complicated that standard methods established in pedagogy and psychology are insufficient to precisely determine individual factors hindering effective problem solving.The authors present techniques for rehabilitation training which could compensate for the impairments observed in individual cases. Luria's work has transformed rehabilitation training, enabling the evaluation of rehabilitation principles and methods.Luria's thinking and conceptual style reflect his genius and rich understanding of brain-behavior relationships. As those who have read it agree, Luria demonstrates remarkable insight with his complex analysis and his qualitative analysis is ""breathtaking.

Neuropsychological Aspects of Brain Injury Litigation: A Medicolegal Handbook for Lawyers and Clinicians

by Phil S. Moore

This accessible handbook focuses on the importance of neuropsychological evidence and the role of the neuropsychologist as expert witness in brain injury litigation. This thorough, evidence-based resource fosters discussion between the legal profession and expert neuropsychological witnesses. The chapters reflect collaborations between leading personal injury lawyers and neuropsychologists in the UK. Key issues in brain injury litigation are addressed that are essential to an understanding of the role of the neuropsychologist as expert witness and of neuropsychological evidence for the courts. These include neuropsychological testing, assessment of quantum, vocational rehabilitation, mental capacity, forensic outcomes, the frontal paradox, mild traumatic brain injury and more. Combining the scientific and legal background with practical tips and case examples, this book is valuable reading for legal professionals, particularly those working in personal injury and clinical negligence, as well as trainees, students and clinicians in the field of neuropsychology, neurorehabilitation and clinical psychology.

Neuropsychological Assessment , Fifth Edition

by Muriel Deutsch Lezak Diane B. Howieson Erin D. Bigler Daniel Tranel

Now in its Fifth Edition, Neuropsychological Assessment reviews the major neurobehavioral disorders associated with brain dysfunction and injury. This is the 35th anniversary of the landmark first edition. As with previous editions, this edition provides a comprehensive coverage of the field of adult clinical neuropsychology in a single source. By virtue of the authors' clinical and research specializations, this book provides a broad-based and in-depth coverage of current neuroscience research and clinical neuropsychology practice. While the new edition is updated to include new features and topics, it remains true to the highly-regarded previous editions. Methods for obtaining optimum data are given in the form of hypothesis-testing techniques, clinical tips, and clinical examples. In the seven years since the previous edition, many advancements have been made in techniques for examining brain function and in our knowledge about brain-behavior relationships. For example, a surge of functional imaging data has emerged and new structural imaging techniques have provided exquisite detail about brain structure. For the first time, this edition includes examples of these advancements, many in stunning color. This edition also includes new tools for clinicians such as a neuroimaging primer and a comparison table of the neuropsychological features of progressive dementias. The chapters on assessment procedures include discussion of issues related to test selection and reviews of recently published as well as older test batteries used in general neuropsychological assessment, plus newly developed batteries for specific issues.

Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities

by Vee P. Prasher

Up to the early 1980s neuropsychological assessments of persons with intellectual disability (ID) usually meant an assessment for developmental delay, of intelligence (intelligence quotient testing) or of level of adaptive behavior. Popular tests included the Stanford-Binet, Wechsler Intelligence Scales, Bayley Scales of Infant Development, the Griffin Mental Developmental Scales, and the Vineland Social Maturity Scale. These were assessments of the "overall" level of ability. Arthur Dalton in New York was one of a few pioneering clinicians who at this time, focused on the development of tests for specific areas of cognition in persons with ID. Following his work, sub- quent researchers, in the latter part of the twentieth century, have proposed and dev- oped a number of measures not only to detect the level of cognitive abilities but also to measure decline; a perquisite to the diagnosis of dementia. At the beginning of the twenty-first century as demonstrated in this book, several neuropsychological measures have been developed to aid the clinical diagnosis of dementia/dementia in Alzheimer's disease (AD). Neuropsychological assessments no longer remain the sole responsibility of psychologists, as psychiatrists, resear- ers, ID nurses, neuroscientists, all now play a part in the development and adm- istration of specific tests.

Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities

by Vee P. Prasher

This book reviews important neuropsychological measures currently used in the assessment of dementia by the principal clinicians and researchers associated with the test, offering practical guidance on each test along with an analysis of its limitations.

Neuropsychological Consequences of COVID-19: Life After Stroke and Balint's Syndrome (ISSN)

by Jwala Narayanan Anjana Xavier Jonathan Evans Narinder Kapur Barbara Wilson

Neuropsychological Consequences of COVID-19 focuses on Anjana’s journey as a COVID survivor following a brain injury that left her with a very rare neuropsychological syndrome called Balint’s syndrome, a disorder associated with difficulties in visual and spatial coordination. It is also the first book of its kind to provide a first-hand account from India on surviving brain injury, from diagnosis, recovery and rehabilitation, providing the therapeutic milieu in the Indian context and exploring cultural influences on rehabilitation.Written jointly by Anjana, her neuropsychologist and the international experts in the field of neuropsychology who were also involved in her diagnosis and care, the book highlights how COVID-19, a virus primarily affecting the respiratory system, can also result in a disabling brain injury. It describes Anjana’s recovery and the rehabilitation she received and provides a deeper understanding of this experience of a very rare condition through the views of Anjana herself. In addition, Anjana’s rehabilitation journey stumbles upon many important themes of rehabilitation including cultural sensitivity, personal identity, resilience, role of family and rehabilitation in a low to middle income country.This book is valuable reading for clinical and neuropsychologists, neurologists, other rehabilitation therapists including physiotherapists, occupational therapists, nurses and social work professionals, particularly those interested in cross cultural rehabilitation. It will also be of interest to students in these fields.

Neuropsychological Neurology

by A. J. Larner

Essential to the management of patients suffering from neurological disorders is an understanding of the cognitive aspects of these conditions. This book begins with an outline of the various cognitive domains and how they can be tested, before covering in depth the cognitive deficits seen not only in prototypical neurodegenerative cognitive disorders (Alzheimer's disease, frontotemporal dementias, Huntington's disease, prionoses), but also in other common neurological disorders which may be complicated by cognitive impairment (stroke, multiple sclerosis, Parkinson's disease, brain tumours). This book is an essential reference text for all neurologists, not just those with an interest in cognitive disorders; and for general physicians and specialists who deal with any endocrine, metabolic, vascular, or infective disorders which may compromise cognitive function. Practitioners of professions allied to medicine which involve contact with cognitively impaired patients will also find this text useful.

Neuropsychological Rehabilitation

by Barbara A. Wilson Fergus Gracey Jonathan J. Evans Andrew Bateman

After an introduction to the current theories and research findings related to brain injury rehabilitation, this text presents 20 case studies of adults who sustained severe brain damage caused by traumatic head injuries, encephalitis, stroke, hypoxia and other conditions. Problems that follow such injuries are analyzed in detail; these include loss of self-care skills, memory impairment, and language, reading, visuoperceptual and behavioral difficulties. The chapters describe the lifestyle of each individual before the onset of brain damage and the subsequent symptoms, neuropsychological assessment, rehabilitation, and long-term outcome of their condition. Most chapters include a report by the patient and/or family member, thus enhancing the reader's understanding of the predicaments faced by brain-injured individuals as they learn to cope with traumatic changes in lifestyle. Although improvement for those with severe brain injuries is slow and limited, the patients described in the book made some progress after their admission to rehabilitation services. The exhaustive analysis of each case and a step-by-step description of management will serve as an inspiring and informative guide for students, professionals and other caregivers.

Neuropsychological Rehabilitation of Childhood Brain Injury

by Jonathan Reed Katie Byard Howard Fine

Increasing numbers of children and young people are surviving road traffic accidents and birth complications but are being left with neurological disability. Although a brain injury can be a potentially devastating childhood medical condition Neuropsychological rehabilitation of childhood brain injury explores the developing field of neuropsychology to aid rehabilitation. The book brings together contributions from leading international clinicians and researchers to describe not only what we understand about childhood brain injury but also what has been demonstrated to help and possible innovative directions that can be taken in the future. By including a comprehensive review of the neuropsychological consequences of child brain injury alongside solid research outcomes this book provides an authoritative guide on how to help children with brain injury using neuropsychology.

Neuropsychological Report Writing (Evidence-Based Practice in Neuropsychology)

by Jacobus Donders

All neuropsychologists need to know how to produce evidence-based reports. This book brings together experts to provide an in-depth guide to high-quality report writing in a range of contexts, including evaluations of older adults, psychiatric patients, those with complex medical conditions, schoolchildren, and others. It reviews the fundamental elements of a clinical neuropsychological report and shows how to tailor findings, conclusions, and recommendations to particular audiences, such as referring physicians, school professionals, and legal decision makers. Of special utility, every chapter features excerpts of sample reports, including examples of strong and poor documentation of the same material.

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