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One-Step Generation of a Drug-Releasing Microarray for High-Throughput Small-Volume Bioassays (Springer Theses)
by Seo Woo SongThis thesis demonstrates a technology that enables pipetting-free high-throughput screening (HTS) on a miniaturized platform, eliminating the need for thousands of one-by-one pipetting and conventional liquid handling systems. This platform enhances accessibility to HTS and enables HTS to be used in small-to-medium scale laboratories. In addition, it allows large-scale combinatorial screening with a small number of valuable cells, such as patients’ primary cancer cells. This technique will have a high impact for widespread use of HTS in the era of personalized medicine. In this thesis, the author firstly describes the need and concept of ‘partipetting’ for pipetting-free HTS platform. It is realized by the one-step pipetting and self-assembly of encoded drug-laden microparticles (DLPs) on the microwells. Next, the technical implementations required for the platform demonstration are described. It includes preparation of encoded DLPs, plastic chip fabrication, and realization of automated system. Lastly, screening of sequential drug combinations using this platform is demonstrated. This shows the potential of the proposed technology for various applications.
One Strong Girl: Surviving the Unimaginable, A Mother's Memoir
by S. Lesley BuxtonA mother&’s award–winning account of what it&’s like to lose a daughter to a rare debilitating disease. One Strong Girl is a bold description of what it means to deal with deep sorrow and still find balance and beauty in an age steeped in the denial of death. At ten, India climbed the highest on the rope at gymnastics, yet by sixteen was so weak she was unable to even dress herself. The narrative follows the six-year fight for answers from the medical community. Finally, after the genetic testing of India&’s DNA, it was discovered there were two mutations on her ASAH1 gene, a deadly combination. Today her cells are alive in a research lab at the University of Ottawa. This is a legacy that cuts both ways, a point of pride and pain. One Strong Girl is a story of what it&’s like to outlive an only child. It describes the intensity of loving a dying child and most importantly, the joy to be found, even amidst the sorrow.
One unbounded ocean of consciousness: Simple answers to the big questions in life
by Dr. Tony NaderWorld renowned leader at the core of the Maharishi Foundations, a Harvard graduate neuroscientist, renowned Vedic scholar and world reference in Transcendental Meditation, Dr.Tony Nader formulates in this book a series of fundamental existential questions (what is our purpose in life, do we have true control over our destinies?) and, through the study of Consciousness, brings us answers with practical benefits that aim to give us enlightenment, peace and fulfillment. «In this landmark book, Dr. Tony Nader presents ideas that can change the world. He proposes profound solutions to questions that have long fascinated and intrigued philosophers and scientists. What is Consciousness, do we have freedom? How to get the best out of life, fulfill wishes and create peace and harmony among peoples and nations? He offers these solutions, based on a simple underlying paradigm, that unifies mind, body, and environment into an ocean of pure Being, Pure Consciousness. A must read for any seeker of answers to the mysteries of life, the absolute and ultimate truth».David Lynch «I want everyone to know what Consciousness is and how to develop it to enjoy the full potential of individual and social life».Dr. Tony Nader Is there some hidden purpose in life, a secret design, a meaningful logic, a goal to be achieved? Where do we come from and where do we go after we leave? Why should we be fighting? Can we choose? Are we free or slaves of destiny, of the laws of nature or of God? As sentient beings who wish to take control of their lives, these questions are fundamental, and everyone ends up making assumptions or strongly subscribing to beliefs about many of them. Those convictions become our underlying "cosmovision" that influences everything we do. I turned to the study of medicine, psychiatry, and neurology to understand why, although we are so similar, we can be so different in our opinions, mentality, and points of view. But the answers to my fundamental questions were too complex and abstract for scientific investigation. It was Transcendental Meditation TM that allowed me to explore them through direct experience, rather than analysis and deduction. This book is dedicated to all seekers of knowledge, scientists, philosophers, teachers, wise leaders, and guides who investigate the secrets of how nature works and the effort to improve life on Earth.
One Week to Win His Heart: Falling For The Pregnant Gp (sydney Surgeons, Book 1000) / One Week To Win His Heart (sydney Surgeons, Book 1000) (Sydney Surgeons Ser.)
by Lucy ClarkCan one week of passion…lead to happily-ever-after?Love has been the last thing on surgeon George Wilmont’s mind since his wife passed away. Until he meets stunning head of orthopedics Melody Janeway on the last week of his lecture tour. Their instant connection explodes into passion, but with only a week before George leaves, can a passionate fling really become a forever love?
One Weekend in Prague
by Alison RobertsEscape to Prague for a weekend in Alison Roberts's latest Harlequin Medical Romance novel, where two strangers meet and share an unlikely but unforgettable connection…For one weekend…Or forever? Before attending a medical conference, trauma specialist Mac meets stranger Hanna under the astronomical clock in Prague. Their intense connection takes him by surprise. Straitlaced Mac has never met someone like free-spirited nurse Hanna, and suddenly he&’s dropping his guard and stepping out of his comfort zone! Their unforgettable and spontaneous weekend together, touring the city and then tangling between the sheets, makes him see the world differently. But what happens when they leave Prague?From Harlequin Medical: Life and love in the world of modern medicine.
One Welfare: A Framework to Improve Animal Welfare and Human Well-being
by Dr Rebeca Garcia PinillosContemporary and thought-provoking, this book provides a definition of the concept of One Welfare: the interconnection between animal welfare, human wellbeing and the environment. The book establishes a conceptual framework, in five sections, resulting from a three month global consultation on a draft proposal comprising nine areas. The book contains: - A one welfare approach which complements and extends the existing one health approach - A range of prestigious contributions from key opinion leaders in the field of animal welfare which help to define the framework - A platform for the development of more collaborative and integrated animal welfare standards and policies One Welfare complements the One Health and Eco Health approaches, enabling full integration of animal welfare within other disciplines; a much needed tool to help improve animal welfare, human wellbeing and environmental components and support worldwide sustainable development goals. Integrating this concept into existing projects could help to foster collaboration to improve human and animal welfare globally. This text is of interest to those working in the fields of animal and human welfare, sustainability and conservation, international development and to all those keen to extend the one health approach to animal welfare and human wellbeing.
One Welfare: A Framework to Improve Animal Welfare and Human Well-being
by Rebeca García PinillosContemporary and thought-provoking, this book provides a definition of the concept of One Welfare: the interconnection between animal welfare, human wellbeing and the environment. The book establishes a conceptual framework, in five sections, resulting from a three month global consultation on a draft proposal comprising nine areas. The book contains: - A one welfare approach which complements and extends the existing one health approach - A range of prestigious contributions from key opinion leaders in the field of animal welfare which help to define the framework - A platform for the development of more collaborative and integrated animal welfare standards and policies One Welfare complements the One Health and Eco Health approaches, enabling full integration of animal welfare within other disciplines; a much needed tool to help improve animal welfare, human wellbeing and environmental components and support worldwide sustainable development goals. Integrating this concept into existing projects could help to foster collaboration to improve human and animal welfare globally. This text is of interest to those working in the fields of animal and human welfare, sustainability and conservation, international development and to all those keen to extend the one health approach to animal welfare and human wellbeing.
One Welfare Animal Health and Welfare, Food Security and Sustainability (One Welfare)
by Inger Anneberg Donald Broom Maria Camila Ceballos Antoni Dalmau Francisco Galindo Carmen Gallo Luciandra Macedo Toledo Xavier Manteca Lohendy Muñoz-Vargas Mateus J.R. Costa Catherine Devitt Warren Hidalgo-Jara Adolfo Sansolini Peter StevensonThis thought-provoking book explores the link between animals, people and their social and physical environments in relation to livestock farming, food safety, food security and sustainability. Providing an overview of livestock farming and animal related food production systems in a one welfare context, One Welfare: Animal Health and Welfare, Food Security and Sustainability begins by considering the interconnections of animals, humans and their environment. It then expands into the food production system, and considers the integration of positive welfare, stress, use of welfare indicators and the economic perspective. Written by a team of international experts, and with a foreword by Andrea Gavinelli, Head of the Animal Welfare Unit in the Health and Food Safety Directorate General of the European Commission, it connects theory with best practice examples and case studies from both organizations and individuals that have successfully implemented a one welfare approach. Essential reading for academics and practitioners who work within farming, food systems and international development, this ground-breaking text is also an important read for veterinary and animal welfare professionals.
One Welfare in Practice: The Role of the Veterinarian (CRC One Health One Welfare)
by Tanya StephensAnimal welfare has long been recognised as central to the role of the veterinary professional, but this is increasingly aligned with the welfare of humans and the broader environment in which we co-exist. This is the first book dedicated to the role of the veterinarian in One Welfare, a concept that recognises the interconnections between animal welfare, human wellbeing, and the environment. The book demonstrates, through a wide range of international case studies, why professional ethics and the use of good evidence is integral to this role. Contributors bring a rich variety of writings, each with their own perception of the role of the veterinarian in improving animal welfare and human wellbeing. One Welfare in Practice: The Role of the Veterinarian emphasises the importance of interdisciplinary collaboration and solutions: it is essential that veterinary practitioners recognise when other professionals or disciplines need to be consulted to benefit both animals and humans. With its multiple, fascinating approaches to One Welfare, this book will inform and inspire the veterinarian to find areas where collaborative action reaps the greatest rewards. This unique book shows how veterinarians can and are contributing to improving animal and human welfare, offering practical advice as to how the profession can further engage in One Welfare in a range of settings.
One Word at a Time: A Road Map for Navigating Through Dyslexia and Other Learning Disabilities
by Linda G. TesslerA unique and groundbreaking resource guide that is informative, insightful and inspiring, this book is Tessler's brave and honest account of her lifelong struggles with dyslexia. Culled from her experiences as a psychologist and scholar specializing in learning disabilities and as the parent of a son who struggles with dyslexia, she brings together sound psychological principles with personal knowledge.
One Word from God Can Change Your Health
by Gloria Copeland Kenneth CopelandThis book is a list of articles by various people including Kenneth and Gloria Copeland, Marty Copeland, Charles Capps and others. All of these articles have to do with healing.
One World Health: An Overview of Global Health
by Lord Nigel CrispThis brand new textbook presents a new approach to the teaching and understanding of global health. It describes the shared opportunities but also the problems that we all face, wherever we live, and the particular needs of the poorest people in every society. Covering subjects from epidemics and climate change, the need to staff and resource health services appropriately, the rich potential of science and technology, and the impacts of social and political change in the world around us, all is presented at a level appropriate for the student looking to gain an understanding of this broad and developing area.
Onko-Nephrologie
by Dirk Jäger Martin ZeierZwischen Nierenerkrankungen und Niereninsuffizienz einerseits und onkologischen Erkrankungen andererseits bestehen komplexe wechselseitige Beziehungen. Die vielfachen Zusammenhänge, die erforderliche Diagnostik und die therapeutischen Konsequenzen, die sich daraus ableiten, sind systematisch und fundiert in diesem Buch beschrieben. Nierenerkrankungen sind wichtige Komorbiditäten bei Krebserkrankungen, beeinflussen deren Verlauf und sind bei der Therapie zu berücksichtigen; maligne Erkrankungen wirken sich unmittelbar oder über nephrotoxische Therapieverfahren auf die Funktion der Nieren aus. Die Wechselwirkungen bei einzelnen Nierenerkrankungen und den wichtigsten Tumorformen und –therapien werden gezielt in eigenen Kapiteln dargestellt.
Onkologische Krankenpflege
by Patrick Jahn Andrea Gaisser Marika Bana Christoph Renner100% Onkologische Pflege! Dieses Buch bietet allen Pflegenden und Teilnehmenden der Fachweiterbildung zur onkologischen Pflegefachperson umfassendes, aktuelles Fachwissen für die spezielle Betreuung ihrer Patienten. Lernen Sie solide Grundlagen, z.B. wie maligne Tumoren entstehen und wachsen, wie man sie erkennt und welche Probleme bei der Behandlung auftreten können, sowie spezielle Kompetenzen, um pflegerisch angemessen zu handeln. Das Standardwerk ist der ideale Begleiter für die Weiterbildung und zum Nachschlagen für die tägliche Praxis.Empfohlen von der Konferenz Onkologischer Kranken- und Kinderkrankenpflege (KOK), der Onkologie Pflege Schweiz (OPS) und der Arbeitsgemeinschaft hämatologischer und onkologischer Pflegepersonen in Österreich (AHOP).
Onkologische Rehabilitation: Grundlagen, Methoden, Verfahren und Wiedereingliederung
by Richard CrevennaDurch die steigenden Überlebensraten in der Krebstherapie trägt die onkologische Rehabilitation wesentlich zur Verbesserung des funktionellen Status, der Lebensqualität und der Partizipation onkologischer Patienten bei. Erstmalig im deutschen Sprachraum präsentiert dieses Buch unter Einbindung der jeweiligen Experten die Aspekte und Vielfalt der Methoden sowie die unterschiedlichen Verfahren in der Rehabilitation von Krebspatienten. Der Grundlagenteil geht dabei auf Rahmenbedingungen, Voraussetzungen und Bausteine der onkologischen Rehabilitation ein. Des Weiteren werden rehabilitative Strategien zur Verbesserung von relevanten Begleitsymptomen, wie u.a. Erschöpfbarkeit, Tagesmüdigkeit, Polyneuropathie, Schmerz, Beweglichkeits- und Ernährungsstörungen, reaktive Traurigkeit (Depression), sexuelle Funktionsstörungen, Inkontinenz und Lymphödem vorgestellt. Eine zunehmend wichtige Rolle für Patienten im arbeitsfähigen Alter spielen Zukunftsthemen wie „Arbeitsfähigkeit“ und „Return to work“. Das Buch ist ein unverzichtbarer Leitfaden für Ärzte und Therapeuten, die in der Nachbetreuung onkologischer Patienten tätig sind.
Online-Assessment: Grundlagen und Anwendung von Online-Tests in der Unternehmenspraxis
by Heinke SteinerImmer mehr Unternehmen nutzen Online-Assessments, um Potenziale von Bewerbern oder Mitarbeitern via Internet zu testen. Online-Tests sind effizient und mittlerweile auch für mittelständische Unternehmen erschwinglich - doch sie haben auch ihre Grenzen. In diesem Buch zeigen erfahrene Personaler, was bei der Planung und dem Einsatz zu beachten ist und in welchen konkreten Bereichen Online-Tests sinnvoll eingesetzt werden können: Von der Vorselektion und dem Personalmarketing, über die Personalauswahl und -entwicklung, bis hin zu besonderen Einsatzgebieten wie Karriereberatung und Erfassung interkultureller Kompetenzen. Diese Darstellung wird eingerahmt von wissenschaftlichen und technischen Grundlagen sowie einem Überblick über neueste Entwicklungen und Trends. Fallbeispiele aus führenden Unternehmen, Checklisten zu Erfolgskriterien sowie eine kommentierte Übersicht über Anbieter von Online-Tests machen dieses Buch zu einem unverzichtbaren Leitfaden für alle, die Online-Assessments einsetzen möchten, aber auch für jene, die sich einen ersten Überblick über die Thematik verschaffen wollen.
Online Child Sexual Exploitation: Treatment and Prevention of Abuse in a Digital World
by Ernesto CaffoThis book examines the modern pandemic of online child sexual exploitation (OCSE). It explores the prevalence, perpetration, impact, and victimization of as well as therapy for child sexual exploitation and its interaction with child sexual abuse. Chapters discuss OCSE from neuropsychological, epidemiological, neurological, behavioral, psychological, clinical, neurobiological and epigenetic perspectives. The volume also addresses the physical and mental impact of early exposure to pornography. The book serves as a resource on an issue that is proving exponentially complex as technology ceaselessly evolves at a faster rate than its consequences can be understood and addressed. Key areas of coverage include:Neuropsychological changes and dysfunctional coping mechanisms resulting from both online and offline child sexual abuse.The psychological, emotional, and physical impacts (e.g., depression, anxiety, PTSD, and self-harm) of child sexual abuse.Prevention and early intervention strategies, including scalable technological responses.Developing a public health approach to preventing and addressing online child abuse and exploitation.Porn culture and its impact on children, adolescents, and emerging adults.The neurobiology and epigenetic impact of trauma. This book is a must-have resource for researchers, clinicians, and graduate students in child and school psychology, public health, social work as well as interrelated disciplines, including neuropsychology, neurobiology, sociology, anthropology, and educational policy and politics.
Online Cognitive Behavioral Therapy: An E-mental Health Approach to Depression and Anxiety
by Nazanin Alavi Mohsen OmraniThis book aims to provide the clinicians with details of online cognitive behavioral therapy (CBT) to facilitate care delivery for patients struggle with depression and anxiety. Chapters cover some of the most fundamental concepts for successful treatment, including experiments, action plans evidence, and the guidelines for managing, thoughts, feelings, and other key concerns. Designed to be a reader-friendly guide, each chapter opens with a summary of the content and a recap of concepts covered in previous sections, making this highly functional for individual chapter or whole book use. Each chapter also includes recommended tables and chart to facilitate the documentation of each recommended session, making this highly practical resource a vital tool for those who treat patients suffering from these particular mental health concerns.
Online-Gentests: Eine kritische Analyse der Chancen und Risiken unter besonderer Berücksichtigung rechtlicher und ethischer Aspekte
by Caroline LehmannOnline-Gentests oder Direct-to-Consumer (DTC)-Gentests sind kommerziell verfügbare Untersuchungen zur Bestimmung individueller genetischer Merkmale eines Menschen. Online-Gentests werden weltweit über das Internet ohne Beteiligung eines Arztes verkauft. Die Entwicklung dieses Marktes floriert, jedoch sind durch die neuen Testverfahren auch Risiken entstanden. Anhand einer Marktanalyse entschlüsselt die vorliegende Arbeit die DTC-Branche und zeigt auf, dass die online verfügbaren Gentest-Angebote auf nahezu alle Lebensbereiche des Menschen ausgerichtet sind. Die Angebote genetischer Analysen reichen von der Auswahl des optimalen Partners über Vaterschaftstests bis hin zur Erhebung genetischer Risikoprofile für Krebserkrankungen oder die Vorhersage der Lebenserwartung; sogar Analysen des gesamten menschlichen Genoms sind über das Internet bestellbar und können ohne ärztliche Begleitung durchgeführt werden. Der Trend der Online-Gentests demonstriert eindrucksvoll die neuen Herausforderungen unserer Zeit. Vor dem Hintergrund aktueller technischer Entwicklungen in der Gendiagnostik setzt sich die Arbeit mit der rechtlichen Zulässigkeit sowie den Chancen und Risiken auseinander, die mit der Durchführung kommerzieller Erbgut-Analysen verbunden sind. Dies eröffnet sowohl die ethische Diskussion um Online-Gentests als auch die Frage nach Lösungsansätzen. Ob und inwieweit gesetzgeberischer Handlungsbedarf besteht, wird abschließend anhand von Lösungsmöglichkeiten erarbeitet.
Online Intermediaries for Co-Creation
by Christoph W. KünneThis book investigates the powerful role of online intermediaries, which connect companies with their end customers, to facilitate joint product innovation. Especially in the healthcare context, such intermediaries deploy interactive online platforms to foster co-creation between engaged healthcare consumers and innovation-seeking healthcare companies. In three empirical studies, this book outlines the key characteristics of online intermediaries in healthcare, their distinct strategies, and the remaining challenges in the field. Readers will also be introduced to the stages companies go through in adopting such co-created solutions. As such, the work appeals for both its academic scope and practical reach.
Online-Marketing für die erfolgreiche Apotheke: Website, SEO, Social Media, Werberecht
by Alexandra Köhler Mirko GründerDieses Buch verschafft Ihnen als Apothekerin und Apotheker einen Überblick über die Welt des Online-Marketings und gibt Ihnen konkrete Anleitungen und Tipps für die Umsetzung in Ihrer Apotheke. Was muss ich bei der Website beachten? Wie kann ich mein Ranking in Suchmaschinen erhöhen? Welche besonderen Rechtsvorschriften sind für Apotheken beim Marketing zu beachten? Antworten auf diese Fragen und viele weitere praxisnahe Tipps zum erfolgreichen Online-Marketing finden Sie und Ihr Team in diesem Ratgeber! Aus dem Inhalt: Grundlagen des Marketings und der Pressearbeit; Die Apotheken-Website: Aufbau, Gestaltung, Inhalte und Usability; SEO: Wie funktionieren Suchmaschinen?; Empfehlungsmarketing und Umgang mit Bewertungsportalen; Vorstellung von reichweitenstarken Social-Media-Plattformen; Jede Menge Content-Ideen für Ihre Kanäle; Rechtsvorschriften und juristische Fallstricke im Online-Marketing; IT-Sicherheit in der Apotheke: Virenschutz, Back-ups, Zugriffsrechte & Co.
Online-Marketing für die erfolgreiche Apotheke
by Alexandra SchrammDie Internetpräsenz wird für Apotheken wichtiger, um Kunden und Patienten zu erreichen. Dieses Buch führt ein in Marketing-Grundlagen, Websites, Suchverzeichnisse, Pressearbeit, Newsletter, Twitter, Blogs und Apps. Daneben gibt es Hintergrundwissen über Rechtsvorschriften (Heilmittelwerbegesetz, Berufs- und Wettbewerbsrecht), Datenschutzbestimmungen, IT-Sicherheit und Umgang mit IT-Dienstleistern. Jedes Kapitel bietet mit Checklisten, Anleitungen und Experten-Interviews wertvolle Tipps, wie mit geringem Aufwand größter Nutzen erzielt werden kann.
Online-Marketing für die erfolgreiche Arztpraxis: Website, SEO, Social Media, Werberecht (Erfolgskonzepte Praxis- & Krankenhaus-Management)
by Alexandra Köhler Mirko GründerDieses Buch verschafft Ihnen als niedergelassene Ärztin bzw. Arzt einen Überblick über die Welt des Online-Marketings und gibt Ihnen konkrete Anleitungen und Tipps für die Umsetzung in Ihrer Arztpraxis. Was muss ich bei der Praxis-Website beachten? Wie kann ich mein Ranking in Suchmaschinen erhöhen? Welche besonderen Rechtsvorschriften für Ärzte beim Marketing sind zu beachten? Antworten auf diese Fragen und viele weitere praxisnahe Tipps zum idealen Online-Marketing finden Sie in diesem Buch. Aus dem Inhalt: Grundlagen des Marketings und der Pressearbeit, Die Praxis-Website: Aufbau, Gestaltung, Inhalte und Usability, SEO: Wie funktionieren Suchmaschinen? Die wichtigsten Maßnahmen, Empfehlungsmarketing und Umgang mit Bewertungsportalen, Vorstellung von reichweitenstarken Social-Media-Plattformen, Rechtsvorschriften und juristische Fallstricke im Online-Marketing. IT-Sicherheit in der Praxis: Virenschutz, Back-ups, Zugriffsrechte & Co.
Online-Marketing für die erfolgreiche Arztpraxis
by Alexandra SchrammDie Autorin führt in diesem ersten Buch zum Thema umfassend in den Bereich Online-Marketing für Ärzte ein. Dabei stellt sie neue Trends in den sozialen Netzwerken wie Twitter oder Blogs vor, aber auch neue Anwendungen wie z. B. Apps. Anhand konkreter Beispiele und Checklisten erfahren Leser, wie die Marketing-Maßnahmen auf die eigene Situation angewandt werden können. Das Handbuch enthält Experteninterviews und liefert zahlreiche Tipps und Tricks für die Umsetzung in die Praxis.
Online-Marketing für die erfolgreiche Zahnarztpraxis
by Alexandra SchrammDie Autorin führt umfassend in das Online-Marketing für Zahnarztpraxen ein. Dabei stellt sie neue Trends in den sozialen Netzwerken wie Twitter oder Blogs vor, aber auch aktuelle Anwendungen wie z. B. Apps. Anhand konkreter Beispiele und Checklisten erfahren Leser, wie die Marketing-Maßnahmen auf die eigene Situation angewandt werden können. Der Band bietet viel Praxis-Know-how, zahlreiche Experteninterviews und darüber hinaus eine begleitende Website.