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Type 1 Diabetes in Adults: Principles and Practice
by Serge Jabbour Elizabeth A. StephensRecent research in diabetes has proven Type 1 diabetes is no longer only a juvenile disease. It has been projected adult Type 1 diabetes will increase 40% from 1997-2010, and as our understanding of the pathogenesis of Type 1 and Type 2 diabetes grows - it is apparent that some cases previously classified as Type 2 are actually adult onset Type 1 d
Type 2 Diabetes: Your Healthy Living Guide
by American Diabetes AssociationOver 20,000 units sold of the third edition aloneCompletely reworked from the ground up, this new edition of Type 2 Diabetes: Your Healthy Living Guide is better than ever. Rewritten with the help of a team of diabetes experts, this ADA bestseller is now friendlier, easier-to-read, better designed, and more comprehensive. This is one book every person with type 2 diabetes needs on their bookshelf.
Type 2 Diabetes: Cardiovascular And Related Complications And Evidence-based Complementary Treatments
by Robert Fried Richard M. CarltonBoca Raton : CRC Press, 2017. | Includes index
Type 2 Diabetes: Principles and Practice, Second Edition
by Barry J. Goldstein Dirk Müller–WielandThe incidence and prevalence of type 2 diabetes mellitus have increased dramatically in modernized and developing nations over the past few decades. Thoroughly revised and expanded, this Second Edition responds to the epidemic and supplies a current overview and guide to the management of diabetes in the modern healthcare environment. This Second E
Type 2 Diabetes
by Claire StockerDiabetes is now reaching epidemic proportions, and the associated complications of this disease can be disabling and even life-threatening. In Type 2 Diabetes: Methods and Protocols, leading investigators provide up-to-date explanations of commonly used laboratory protocols used in diabetes research. Covering the commonly described in vivo and in vitro model systems, the volume ultimately leads to an overall view of how cellular dysfunction and degeneration leads to susceptibility and diabetes disease progression. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include brief introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and expert notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Type 2 Diabetes: Methods and Protocols offers succinct, proven techniques to aid research scientists and clinicians in continuing the study of this debilitating disease.
Type 2 Diabetes for Beginners
by Phyllis BarrierWith this book readers learn how to take care of themselves or someone they love when diagnosed with type 2 diabetes. Completely updated, this second edition of Type 2 Diabetes for Beginners provides insight and information on how to live with diabetes. Checking blood sugar, taking medications, planning meals, losing weight, combating stress and depression, and dealing with long-term diabetes problems are just a few of the topics covered in this friendly, easy-to-read guide.
Type 2 Diabetes in Children and Adolescents
by Arlan L. Rosenbloom Janet H. SilversteinEpidemiology of type 2 diabetes in youth, including evidence for and magnitude of the epidemic; pathophysiology in youth, case-finding criteria, and when to consider the possibility of type 2; and how to diagnose and treat diabetes in children and adolescents.
Type 2 Diabetes, Pre-Diabetes, and the Metabolic Syndrome
by Ronald A. CodarioDiagnosing and managing type 2 diabetes presents an enormous challenge to the primary care provider confronted with multiple emerging scientific insights, therapeutic strategies and risk reduction principles. In Type 2 Diabetes, Pre-Diabetes, and the Metabolic Syndrome: The Primary Care Guide to Diagnosis and Management, Second Edition, Ronald A. Codario, M.D., FACP -- a well-known and highly respected authority on diabetes -- details the state-of-the-art in diagnosing, managing and attenuating risks in patients with this disease. Utilizing his extensive experience in private practice, medical education and clinical research for over 35 years, Dr. Codario explains in simple clinical terms, the current understanding of the pathophysiology of diabetes, the latest clinical trials, developing controversies, updates on new medications and an expanded section on Special Populations. With his unique, multiple board certifications in clinical hypertension, vascular medicine, internal medicine, vascular ultrasound and clinical lipidology, Dr. Codario provides practical guidelines for treatment with insulin and oral agents, lipid and hypertension control and comprehensive risk reduction strategies. Extensively reviewed are the metabolic syndrome, the role of exercise and nutrition, and key issues associated with herb and nutriceutical use. Illustrative case studies in diabetes management, an outstanding bibliography of suggested readings, and extensive chapter subheadings for quick reference make this book a practical, easy-to-read guide for dealing with this killer disease. Type 2 Diabetes, Pre-Diabetes, and the Metabolic Syndrome: The Primary Care Guide to Diagnosis and Management, Second Edition is the direct result of many years of listening, teaching, lecturing and empathizing with fellow primary care providers and their patients in the ongoing fight against diabetes. Like the internationally acclaimed first edition, this is a must read and invaluable guide for all primary care providers, students, caregivers and patients battling the ravages of this ever increasing epidemic.
Type 2 Immunity: Methods and Protocols (Methods in Molecular Biology #1799)
by R. Lee ReinhardtThis book provides researchers the opportunity to investigate type-2-associated diseases in their laboratories. Beginning with chapters describing various models of type-2 immunity, the volume then continues by detailing cellular protocols designed to identify, characterize, and assess the function of key adaptive and innate immune cells involved in type-2 inflammation; approaches to isolate and evaluate specific cellular subsets at the genetic, epigenetic, and molecular level; protocols to assess type-2 immunity and its relationship to organismal and metabolic systems (ex. Microbiome). This book concludes with a section that explores the use of primary human cells in evaluating relevance to the clinic. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Vital and authoritative, Type 2 Immunity: Methods and Protocols aims to provide a broad network of methods that can be used to develop a hypothesis and investigate its potential from bench to beside.
Type 2 Immunity: Methods and Protocols (Methods in Molecular Biology #1799)
by R. Lee ReinhardtThis book provides researchers the opportunity to investigate type-2-associated diseases in their laboratories. Beginning with chapters describing various models of type-2 immunity, the volume then continues by detailing cellular protocols designed to identify, characterize, and assess the function of key adaptive and innate immune cells involved in type-2 inflammation; approaches to isolate and evaluate specific cellular subsets at the genetic, epigenetic, and molecular level; protocols to assess type-2 immunity and its relationship to organismal and metabolic systems (ex. Microbiome). This book concludes with a section that explores the use of primary human cells in evaluating relevance to the clinic. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Vital and authoritative, Type 2 Immunity: Methods and Protocols aims to provide a broad network of methods that can be used to develop a hypothesis and investigate its potential from bench to beside.
Type 3 Secretion Systems
by Matthew L. Nilles Danielle L. Jessen CondryThis volume discusses various basic and advanced methods and protocols that have been proven to be successful among certain bacterial species, or a family of species, in type III secretion systems (T3S system). The chapters in this book cover topics such as: site-directed mutagenesis and its application in studying the interactions of T3S components; use of transcriptional control to increase expression and secretion of heterologous proteins in T3S systems; fractionation techniques to examine effector translocation; detecting immune responses to T3S systems; mouse immunization with purified needle proteins from T3S systems and the characterization of the immune responses to these proteins; and detection of protein interactions in T3S systems using yeast 2-hybrid analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and comprehensive, Type 3 Secretion Systems: Methods and Protocols is a valuable resource for anyone interested in learning about the fascinating and ever-changing T3S systems.
Type IV Secretion in Gram-Negative and Gram-Positive Bacteria (Current Topics in Microbiology and Immunology #413)
by Steffen Backert Elisabeth GrohmannType IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians.
Typhoid Mary
by Judith Walzer LeavittShe was an Irish immigrant cook. Between 1900 and 1907, she infected twenty-two New Yorkers with typhoid fever through her puddings and cakes; one of them died. Tracked down through epidemiological detective work, she was finally apprehended as she hid behind a barricade of trashcans. To protect the public's health, authorities isolated her on Manhattan's North Brother Island, where she died some thirty years later.This book tells the remarkable story of Mary Mallon--the real Typhoid Mary. Combining social history with biography, historian Judith Leavitt re-creates early-twentieth-century New York City, a world of strict class divisions and prejudice against immigrants and women. Leavitt engages the reader with the excitement of the early days of microbiology and brings to life the conflicting perspectives of journalists, public health officials, the law, and Mary Mallon herself.Leavitt's readable account illuminates dilemmas that continue to haunt us. To what degree are we willing to sacrifice individual liberty to protect the public's health? How far should we go in the age of AIDS, drug-resistant tuberculosis, and other diseases? For anyone who is concerned about the threats and quandaries posed by new epidemics, Typhoid Mary is a vivid reminder of the human side of disease and disease control.
The Typhoon Truce, 1970: Three Days in Vietnam when Nature Intervened in the War
by Robert F. CurtisIt wasn&’t rockets or artillery that came through the skies one week during the war. It was the horrific force of nature that suddenly put both sides in awe. As an unofficial truce began, questions and emotions battled inside every air crewman&’s mind as they faced masses of Vietnamese civilians outside their protective base perimeters for the first time. Could we trust them not to shoot? Could they trust us not to drop them off in a detention camp? Truces never last, but life changes a bit for all the people involved while they are happening. Sometimes wars are suspended and fighting stops for a while. A holiday that both sides recognize might do it, as happened in the Christmas truce during World War I. Weather might do it, too, as it did in Vietnam in October 1970. The &“typhoon truce&” was just as real, and the war stopped for three days in northern I Corps--that area bordering the demilitarized zone separating South Vietnam from the North. The unofficial &“typhoon truce&” came because first, Super Typhoon Joan arrived, devastating all the coastal lowlands in I Corps and further up into North Vietnam. Then, less than a week later came Super Typhoon Kate. Kate hit the same area with renewed fury, leaving the entire countryside under water and the people there faced with both war and natural disaster at the same time. No one but the Americans, the foreign warriors fighting throughout the country, had the resources to help the people who lived in the lowlands, and so they did. For the men who took their helicopters out into the unending rain it really made little difference. Perhaps no one would shoot at them for a while, but the everyday dangers they faced remained, magnified by the low clouds and poor visibility. The crews got just as tired, maybe more so, than on normal missions. None of that really mattered. The aircrews of the 101st Airborne went out to help anyway, because rescuing people was now their mission. In this book we see how for a brief period during an otherwise vicious war, saving life took precedence over bloody conflict.
The Tyranny of Health: Doctors and the Regulation of Lifestyle
by Michael FitzpatrickTopical and controversial The Tyranny of Health exposes the dangers of the explosion of health awareness for both patients and doctors, using straightforward language to explain the latest health statistics and research findings. Michael Fitzpatrick, a full-time inner-city GP, argues from his day-to-day experience in the surgery that health propaganda is having a very unhealthy effect on the nation. Patients are made unnecessarily anxious as a result of health scares which have greatly exaggerated the risks of everyday activities such as eating beef, sunbathing and having sex. Doctors no longer seem content with treating disease but are encouraged by the government to tell people how to live more and more aspects of their lives.Michael Fitzpatrick concludes that doctors should stop trying to make people virtuous. He argues that we need to establish a clear boundary between the worlds of medicine and politics, so that doctors can concentrate on treating the sick - and leave the well alone.
Tyranny of the Gene: Personalized Medicine and Its Threat to Public Health
by James TaberyA revelatory account of how power, politics, and greed have placed the unfulfilled promise of personalized medicine at the center of American medicineThe United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our genomes—have promised to usher in a new era of miracle cures. Advocates of this gene-guided health-care practice foresee a future where skyrocketing costs can be curbed by customization and unjust disparities are vanquished by biomedical breakthroughs. Progress, however, has come slowly, and with a price too high for the average citizen.In Tyranny of the Gene, James Tabery exposes the origin story of personalized medicine—essentially a marketing idea dreamed up by pharmaceutical executives—and traces its path from the Human Genome Project to the present, revealing how politicians, influential federal scientists, biotech companies, and drug giants all rallied behind the genetic hype. The result is a medical revolution that privileges the few at the expense of health care that benefits us all.Now American health care, driven by the commercialization of biomedical research, is shifting focus away from the study of the social and environmental determinants of health, such as access to fresh and nutritious food, exposure to toxic chemicals, and stress caused by financial insecurity. Instead, it is increasingly investing in &“miracle pills&” for leukemia that would bankrupt most users, genetic studies of minoritized populations that ignore structural racism and walk dangerously close to eugenic conclusions, and oncology centers that advertise the perfect gene-drug match, igniting a patient&’s hope, and often dashing it later.Tyranny of the Gene sounds a warning cry about the current trajectory of health care and charts a path to a more equitable alternative.
U.S. Army Ambulances & Medical Vehicles in World War II (Casemate Illustrated Special)
by Didier AndresA “cool compendium” of photos and information about the vehicles that helped save American troops’ lives (Cybermodeler).Of all the armies involved in World War II, the U.S. Army developed the most sophisticated system for the transport and treatment of injured and sick soldiers, pushing the boundaries of available technology to give their men the best chance of not only survival but a full recovery.Each infantry regiment had a medical detachment tasked with conserving the strength of the regiment by not only providing medical and dental treatment but also undertaking all possible measures to keep the regiment healthy. In combat they would provide emergency medical treatment on the battlefield, then move casualties to aid stations they had established. At aid stations, casualties would be triaged, stabilized, and treated before being moved on for further treatment. Vehicles formed a crucial part of the Medical Detachment’s equipment.This fully illustrated, comprehensive book covers all types of medical vehicles used both in-theater and in the United States, including ambulances and technical support vehicles. It details vehicle markings modifications, for use in the evacuation of troops from the battlefield, and the other uses these vehicles were adapted for during the war—including their use as “Clubmobiles” and “Chuck Wagons” by the American Red Cross.
The U.S. Commitment to Global Health: Recommendations for the Public and Private Sectors
by Institute of MedicineHealth is a highly valued, visible, and concrete investment that has the power to both save lives and enhance the credibility of the United States in the eyes of the world. While the United States has made a major commitment to global health, there remains a wide gap between existing knowledge and tools that could improve health if applied universally, and the utilization of these known tools across the globe. The U.S. Commitment to Global Health concludes that the U.S. government and U.S.-based foundations, universities, nongovernmental organizations, and commercial entities have an opportunity to improve global health. The book includes recommendations that these U.S. institutions increase the utilization of existing interventions to achieve significant health gains; generate and share knowledge to address prevalent health problems in disadvantaged countries; invest in people, institutions, and capacity building with global partners; increase the quantity and quality of U.S. financial commitments to global health; and engage in respectful partnerships to improve global health. In doing so, the U.S. can play a major role in saving lives and improving the quality of life for millions around the world.
The U.S. Experience with No-Fault Automobile Insurance
by Paul Heaton James M. Anderson Stephen J. CarrollNo-fault regimes, a formerly popular alternative to the tort compensation system for auto-accident victims, have gradually lost support. Over time, premiums and claim costs have grown in no-fault states relative to other states, primarily driven by explosive medical cost increases. No-fault and tort states have also converged across many domains affecting costs, including excess claiming, litigation patterns, and noneconomic-damage payments.
U.S. Health in International Perspective
by Steven H. WoolfThe United States is among the wealthiest nations in the world, but it is far from the healthiest. Although life expectancy and survival rates in the United States have improved dramatically over the past century, Americans live shorter lives and experience more injuries and illnesses than people in other high-income countries. The U. S. health disadvantage cannot be attributed solely to the adverse health status of racial or ethnic minorities or poor people: even highly advantaged Americans are in worse health than their counterparts in other, "peer" countries. In light of the new and growing evidence about the U. S. health disadvantage, the National Institutes of Health asked the National Research Council (NRC) and the Institute of Medicine (IOM) to convene a panel of experts to study the issue. The Panel on Understanding Cross-National Health Differences Among High-Income Countries examined whether the U. S. health disadvantage exists across the life span, considered potential explanations, and assessed the larger implications of the findings. U. S. Health in International Perspective presents detailed evidence on the issue, explores the possible explanations for the shorter and less healthy lives of Americans than those of people in comparable countries, and recommends actions by both government and nongovernment agencies and organizations to address the U. S. health disadvantage.
U.S. Healthcare and the Future Supply of Physicians
by Eli Ginzherg Panes MinogiannisMany different sectors of modern society influence the nation's healthcare system. Government, health insurance companies, managed care organizations, academic health centers, the pharmaceutical industry, and other groups all affect healthcare. In the areas of medical access, cost, and quality, the physician remains the key to the efficiency and effectiveness of healthcare services. Eli Ginzberg and Panos Minogiannis, in Ginzberg's final book, examine the supply of health personnel in the United States. They consider the ways it has been influenced by federal and state legislation, healthcare financing, the transformation of the hospital, managed care, and health trends in the last part of the twentieth century. Through this historical approach, the book identifies key moments in U.S. health policy history that have led to problems in the geographical distribution of medical personnel, gender and race representation in the health personnel pool, and subsequent attempts to resolve these problems. This volume pays special attention to current trends in healthcare and tries to forecast the direction of the debate over health personnel supply in the coming years. Chronic care conditions and the ageing of the population on the one hand and the penetration of managed care and the subsequent transformation of American hospitals on the other converge to present policymakers with tremendous challenges in financing healthcare. Ginzberg and Minogiannis argue that a more balanced production and distribution of U.S. health personnel will go far in easing the financial burden of healthcare and at the same time improve the quality of services provided to the American people.
The U.S. Healthcare System: Origins, Organization and Opportunities
by Joel ShalowitzThe U.S. Health Care System: Origins, Organization and Opportunities provides a comprehensive introduction and resource for understanding healthcare management in the United States. It brings together the many “moving parts” of this large and varied system to provide both a bird’s-eye view as well as relevant details of the complex mechanisms at work. By focusing on stakeholders and their interests, this book analyzes the value propositions of the buyers and sellers of healthcare products and services along with the interests of patients. <p><p> The book begins with a presentation of frameworks for understanding the structure of the healthcare system and its dynamic stakeholder inter-relationships. The chapters that follow each begin with their social and historical origins, so the reader can fully appreciate how that area evolved. The next sections on each topic describe the current environment and opportunities for improvement. <p> Throughout, the learning objectives focus on three areas: frameworks for understanding issues, essential factual knowledge, and resources to keep the reader keep up to date. <p> Healthcare is a rapidly evolving field, due to the regulatory and business environments as well as the advance of science. To keep the content current, online updates are provided at: www.HealthcareInsights.MD. This website also offers a weekday blog of important/interesting news and teaching notes/class discussion suggestions for instructors who use the book as a text. <p> The U.S. Health Care System: Origins, Organization and Opportunities is an ideal textbook for healthcare courses in MBA, MPH, MHA, and public policy/administration programs. In piloting the content, over the past several years the author has successfully used drafts of chapters in his Healthcare Systems course for MBA and MPH students at Northwestern University. The book is also useful for novice or seasoned suppliers, payers and providers who work across the healthcare field and want a wider or deeper understanding of the entire system.
U.S. National Library of Medicine (Images of America)
by Jeffrey S. Reznick Kenneth M. Koyle Medicine, with staff of the US National Library ofThe US National Library of Medicine, on the campus of the National Institutes of Health in Bethesda, Maryland, has been a center of information innovation since its beginnings in the early 19th century. The world’s largest medical library and a federal government agency, it maintains and makes publicly available a diverse and world-renowned collection of materials dating from the 11th to the 21st centuries, and it produces a variety of electronic resources that millions of people around the globe search billions of times each year. The library also supports and conducts research, development, and training in biomedical informatics and health information technology, and it coordinates the National Network of Libraries of Medicine that promotes and provides access to health information in communities across the United States. As the library anticipates its third century of public service, this book offers a visual history of its development from its earliest days through the late 20th century, as the institution has involved generations of visionary leaders and dedicated individuals who experienced the American Civil War, the world wars, the Cold War, and the dawn of the information age.
The U.S. Oral Health Workforce in the Coming Decade: Workshop Summary
by Institute of MedicineAccess to oral health services is a problem for all segments of the U.S. population, and especially problematic for vulnerable populations, such as rural and underserved populations. The many challenges to improving access to oral health services include the lack of coordination and integration among the oral health, public health, and medical health care systems; misaligned payment and education systems that focus on the treatment of dental disease rather than prevention; the lack of a robust evidence base for many dental procedures and workforce models; and regulatory barriers that prevent the exploration of alternative models of care. This volume, the summary of a three-day workshop, evaluates the sufficiency of the U.S. oral health workforce to consider three key questions: What is the current status of access to oral health services for the U.S. population? What workforce strategies hold promise to improve access to oral health services? How can policy makers, state and federal governments, and oral health care providers and practitioners improve the regulations and structure of the oral health care system to improve access to oral health services?
UAVs for Spatial Modelling and Urban Informatics
by Tony H. Grubesic Jake R. Nelson Ran WeiThis book aims to provide a wide range of real-world applications in using unmanned aerial vehicles (UAVs) for geographic observation, spatial modeling, and urban informatics. Specifically, UAVs are incredibly effective platforms for connecting people, places, and technology. This book explores the utility of UAVs for monitoring, measuring, and improving urban infrastructure systems, urban sustainability, and the urban environment. The dynamism of cities provides opportunities for economic, social, and environmental change, but benchmarking and measuring cities continues to be challenging. This challenge is due, at least in part, to a lack of monitoring systems that can collect and analyze data at a granular enough scale to capture the nuance of local phenomena. UAVs offer a promising mechanism to fill this niche, serving as a measurement platform that can rapidly and inexpensively collect data and monitor change in cities. However, their use is fraught with social, operational, regulatory, and technical challenges for successful deployments. This book provides a resource for urbanists (e.g., planners, geographers, sociologists, epidemiologists, engineers), educators, and students who work with geographic information and seek to enhance these data using data and information from unmanned aerial vehicles. At the same time, we provide operational and methodological frameworks for carrying out these advanced analyses in a manner that considers the challenges of incorporating UAVs in research within the urban environment. We provide six unique applications of UAVs for urban analysis, detailing relevant policy and empirical questions, UAV mission parameters, data collection, spatial modeling, and the associated empirical results. Further, we discuss how best to integrate these results into actionable geospatial intelligence and policy development to improve city infrastructure systems, sustainability, the environment, and neighborhood quality.