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The Least Likely Man: Marshall Nirenberg and the Discovery of the Genetic Code (The\mit Press Ser.)
by Franklin H. PortugalHow unassuming government researcher Marshall Nirenberg beat James Watson, Francis Crick, and other world-famous scientists in the race to discover the genetic code.The genetic code is the Rosetta Stone by which we interpret the 3.3 billion letters of human DNA, the alphabet of life, and the discovery of the code has had an immeasurable impact on science and society. In 1968, Marshall Nirenberg, an unassuming government scientist working at the National Institutes of Health, shared the Nobel Prize for cracking the genetic code. He was the least likely man to make such an earth-shaking discovery, and yet he had gotten there before such members of the scientific elite as James Watson and Francis Crick. How did Nirenberg do it, and why is he so little known? In The Least Likely Man, Franklin Portugal tells the fascinating life story of a famous scientist that most of us have never heard of.Nirenberg did not have a particularly brilliant undergraduate or graduate career. After being hired as a researcher at the NIH, he quietly explored how cells make proteins. Meanwhile, Watson, Crick, and eighteen other leading scientists had formed the “RNA Tie Club” (named after the distinctive ties they wore, each decorated with one of twenty amino acid designs), intending to claim credit for the discovery of the genetic code before they had even worked out the details. They were surprised, and displeased, when Nirenberg announced his preliminary findings of a genetic code at an international meeting in Moscow in 1961. Drawing on Nirenberg's “lab diaries,” Portugal offers an engaging and accessible account of Nirenberg's experimental approach, describes counterclaims by Crick, Watson, and Sidney Brenner, and traces Nirenberg's later switch to an entirely new, even more challenging field. Having won the Nobel for his work on the genetic code, Nirenberg moved on to the next frontier of biological research: how the brain works.
The Least of Us: True Tales of America and Hope in the Time of Fentanyl And Meth
by Sam QuinonesFrom the New York Times bestselling author of DREAMLAND, a searing follow-up that explores the terrifying next stages of the opioid epidemic and the quiet yet ardent stories of community repair. Sam Quinones traveled from Mexico to main streets across the United States to create Dreamland, a groundbreaking portrait of the opioid epidemic that awakened the nation. As we struggled to put back the pieces, Quinones was among the first to see the dangers that lay ahead: synthetic drugs and a new generation of kingpins whose product could be made in Magic Bullet blenders. In fentanyl, traffickers landed a painkiller a hundred times more powerful than morphine. They laced it into cocaine, meth, and counterfeit pills to cause tens of thousands of deaths--at the same time as Mexican traffickers made methamphetamine cheaper and more potent than ever, creating, Sam argues, swaths of mental illness and a surge in homelessness across the United States. Quinones hit the road to investigate these new threats, discovering how addiction is exacerbated by consumer-product corporations. "In a time when drug traffickers act like corporations and corporations like traffickers," he writes, "our best defense, perhaps our only defense, lies in bolstering community." Amid a landscape of despair, Quinones found hope in those embracing the forgotten and ignored, illuminating the striking truth that we are only as strong as our most vulnerable. Weaving analysis of the drug trade into stories of humble communities, The Least of Us delivers an unexpected and awe-inspiring response to the call that shocked the nation in Sam Quinones's award-winning Dreamland. SAM QUINONES is a journalist, storyteller, former Los Angeles Times reporter, and author of three acclaimed books of narrative nonfiction, including New York Times bestseller and National Book Critics Circle Award winner Dreamland: The True Tale of America's Opiate Epidemic. "The most original writer on Mexico and the border" (San Francisco Chronicle), he lives with his family in Southern California.
The Left-Hander Syndrome: The Causes and Consequences of Left-Handedness
by Stanley CorenNine out of every ten human beings are naturally right-handed. Those who were not right-handed were feared, shunned, or forcibly retrained in many periods and cultures. Indeed, some members of fundamentalist sects still regard left-handers as in league with the devil, and prejudices against left-handers are reflected in the multiple associations of right with good and left with bad that have become enshrined in everyday language and folklore. A “left-handed compliment” is actually an insult, and the dictionary definition of left-handed includes the terms “awkward,” “clumsy,” “ill-omened,” and “Illegitimate.” In his summary of scientific research into sidedness, Stanley Coren rapidly dismisses the notion of the southpaw as somehow tainted. Increasingly we are coming to understand, however, that left-handedness does have social, educational, medical, and psychological implications. Coren uses entertaining examples to illuminate the paths of research he has followed, and answers vitally important questions such as: What are the neuropsychological and behavioral implications of differences for left-handers themselves, as well as for their parents, teachers, spouses, children, counselors, and physicians? How can we determine our own patterns of sidedness? Are they encoded in our genes? And, very importantly, how can we make the world more comfortable and safer for left-handers? Coren persuasively argues that left-handers are an invisible minority who must define themselves and organize for self-protections in the same way that more visible minorities have done. Much (though not all) of the risk to which left-handers are exposed derives from the fact that the tools they use and the machines they operate are designed for right-handers, a flaw that given heightened public awareness would be easy to correct. Coren advocates a change in the way the right-handed majority treats its left-handed minority to eliminate the risks left-handers face.
The Legacy Continues: A History of the American Society of Colon and Rectal Surgeons and Affiliated Organizations 2000-2024
by David E. Beck Guy R. Orangio Charles E. LittlejohnThe ASCRS Executive Council has authorized production of an updated historical text to commemorate the 125th Anniversary of the Society (2024), a sequel of sorts to From Mathews to the Millennium - A Century of Achievement: A History of the American Society of Colon and Rectal Surgeons 1899-1999. Featuring personal and professional contributions from experienced members of the ASCRS, The Legacy Continues highlights the achievements, advancements and accomplishments of the ASCRS and affiliated societies over last 25 years (2000-2024), including educational efforts and meetings, noteworthy publications, important advances in surgical practice, board administration, research activities, training programs, and surgical leadership. It is an interesting and thought-provoking text not only for ASCRS members but colorectal surgeons worldwide with an interest in the growth and expansion of the field.
The Legal Regulation of Pregnancy and Parenting in the Labour Market
by Grace JamesWhy is the law failing to protect pregnant workers and parents from detrimental treatment in the workplace? This theoretically informed book, which draws on the findings of a large scale, Nuffield Foundation funded, study of pregnancy-related workplace disputes, explores the legal regulation of pregnancy and parenting in the labour market. Using an epistemology that draws primarily on critical feminist debates, theories and critiques, the book adopts a necessarily female standpoint and seeks to answer why, despite positive policy ambitions and ample legislation, law is failing to protect pregnant workers and parents. Whilst sensitive to the limits of law’s ability to bring about social change, the book asks whether it is the direction of current policies that need attention, or the substance of the legislation that is flawed. Is it the application of the law in courts and tribunals that fails working families or the mechanics of the employment dispute resolution and tribunal system that needs adjusting? This book will interest academics, students and practitioners of law and social policy interested in employment law and discrimination.
The Legal, Professional, and Ethical Dimensions of Higher Education In Nursing
by Mable H. SmithThe only volume on higher education law written specifically for nursing faculty, this volume imparts the basic foundations of the legal, professional, and ethical issues that concern faculty on a daily basis. It clearly defines the legal rights of students, professors, and educational institutions along with the case laws supporting those rights. Each chapter contains a vivid legal scenario, related legal principles and theoretical foundations, and critical thinking questions. Written by an author who is both a nurse educator and attorney, the volume emphasizes sound decision making so that readers can successfully navigate the complex legal issues confronting them in the faculty role.
The Legend of Safehaven: A Novel
by R. A. ComunaleThe sequel to R. A. Comunale's highly praised first novel Requiem for the Bone Man follows the continuing story of Dr. Robert Galen and his friends, Robert and Nancy Edison, as they adjust to semiretirement on a mountaintop in northeastern Pennsylvania, raising and caring for the three orphaned Hidalgo children they rescued and adopted. Along the way, the six residents of the mountain interact with a variety of individuals--human and animal--who also are seeking sanctuary, and even redemption, on the property that becomes known as Safehaven. In ways mystical, magical, and even heroic, Comunale once again envelops readers in a fictional world that is often harrowing, but always captivating.
The Legitimacy of Healthcare and Public Health: Anthropological Perspectives (Palgrave Studies in Urban Anthropology)
by Italo Pardo Giuliana B. PratoThe complex, highly problematic, often thorny dynamics of trust and authority are central to the anthropological study of legitimacy. In this book, this sine qua non runs across the in-depth examination of the ways in which healthcare and public health are managed by the authorities and experienced by the people on the ground in urban Europe, the USA, India, Africa, Latin America and the Far and Middle East. This book brings comparatively together anthropological studies on healthcare and public health rigorously based on in-depth empirical knowledge. Inspired by the current debate on legitimacy, legitimation and de-legitimation, the contributions do not refrain from taking into account the impact of the Covid-19 pandemic on the health systems under study, but carefully avoid letting this issue monopolise the discussion. This book raises key challenges to our understanding of healthcare practices and the governance of public health. With a keen eye on urban life, its inequalities and the ever-expanding gap between rulers and the ruled, the findings address important questions on the complex ways in which authorities gain, keep, or lose the public’s trust.
The Legitimacy of Medical Treatment: What Role for the Medical Exception? (Biomedical Law and Ethics Library)
by Sara Fovargue Alexandra MullockWhenever the legitimacy of a new or ethically contentious medical intervention is considered, a range of influences will determine whether the treatment becomes accepted as lawful medical treatment. The development and introduction of abortion, organ donation, gender reassignment, and non-therapeutic cosmetic surgery have, for example, all raised ethical, legal, and clinical issues. This book examines the various factors that legitimatise a medical procedure. Bringing together a range of internationally and nationally recognised academics from law, philosophy, medicine, health, economics, and sociology, the book explores the notion of a treatment, practice, or procedure being proper medical treatment, and considers the range of diverse factors which might influence the acceptance of a particular procedure as appropriate in the medical context. Contributors address such issues as clinical judgement and professional autonomy, the role of public interest, and the influence of resource allocation in decision-making. In doing so, the book explores how the law, the medical profession, and the public interact in determining whether a new or ethically contentious procedure should be regarded as legitimate. This book will be of interest and use to researchers and students of bioethics, medical law, criminal law, and the sociology of medicine. Chapter 6 of this book 'Family perspectives on proper medical treatment for people in prolonged vegetative and minimally conscious states' by Celia Kitzinger and Jenny Kitzinger is available under an open access CC BY NC ND license and can be viewed at: http://preview.ncbi.nlm.nih.gov/books/prevqa/NBK199156/ .
The Leo-Aquarius Connection (Opposites in Love, Medical Zodiac Romances #5)
by Janet Lane WaltersThe nurses stare as he exits the elevator on the Pediatric Unit. “Enter the handsome doctor.” Those are Doctor Caleb Winstone’s words as he steps off the elevator. Though he’s embarrassed, this Leo doctor rolls with the punches. He’s returned home to join an older doctor in the practice. Before long he learns the new nurse manager of the unit is a woman he knows. Of all the women in the world, she is the last one he wants to see. How can he manage to work daily with her? Before the day ends, he discovers his mother has decided who he should marry and the woman is quite willing. Not for him. Suzanna Rollins is an Aquarian and now the guardian of her half-brother who was badly injured in a car accident. She takes the position as nurse manager of the Pediatric unit for several reasons. One is the move from the city re-unites her with college friends, the Grantley Gang. The other is for the excellent Rehab Center. On the day of her arrival, she encounters Caleb. What is he doing here and why? Can she work with the man she fell in and out of love with the night he offered her less than marriage? Caleb’s interest in helping her half-brother gives them more together time than they imagined.
The Leo-Aquarius Connection (Opposites in Love, Medical Zodiac Romances #5)
by Janet Lane WaltersThe nurses stare as he exits the elevator on the Pediatric Unit. “Enter the handsome doctor.” Those are Doctor Caleb Winstone’s words as he steps off the elevator. Though he’s embarrassed, this Leo doctor rolls with the punches. He’s returned home to join an older doctor in the practice. Before long he learns the new nurse manager of the unit is a woman he knows. Of all the women in the world, she is the last one he wants to see. How can he manage to work daily with her? Before the day ends, he discovers his mother has decided who he should marry and the woman is quite willing. Not for him. Suzanna Rollins is an Aquarian and now the guardian of her half-brother who was badly injured in a car accident. She takes the position as nurse manager of the Pediatric unit for several reasons. One is the move from the city re-unites her with college friends, the Grantley Gang. The other is for the excellent Rehab Center. On the day of her arrival, she encounters Caleb. What is he doing here and why? Can she work with the man she fell in and out of love with the night he offered her less than marriage? Caleb’s interest in helping her half-brother gives them more together time than they imagined.
The Leopard in my House: One man’s adventures in cancerland
by Mark Steel'A deep, personal, clever and witty book' Michael Rosen | 'Funny, moving, wise and then very funny again' John O'Farrell | 'clear-eyed, humane and engaging' Observer | 'inspiring' GuardianI feel like there’s a leopard in my house, locked in a room. I’ve contacted the leopard authorities and they assure me they are used to dealing with leopards like this, and they have a plan for removing the leopard. It will take a while, though, and once in a while I can hear it growl.And that’s all very reassuring. Even so, several times a day I think to myself: “Hang on, there’s a leopard in my house.”One morning, while shaving, the comedian Mark Steel noticed that one side of his neck seemed larger than the other. After a whistlestop tour of assorted medical professionals, a consultant delivered the ominous words that would define the next months of his life: ‘I’m afraid it’s not good news, Mr Steel’.And so began a journey into the heart of the NHS, as he embarked on the long and uncertain road to cancer recovery via a range of mildly torturous and entirely miraculous treatments. What, if anything, might he learn about himself – and our capacity for coping with life when times get tough – as he becomes part of a club that one in two British people will ultimately join?A frank and funny diary of one man’s rather trying year, this is an unforgettable and uplifting story of getting ill, getting on with it, and getting better.
The Lesser Bushbaby (Galago) as an Animal Model: Selected Topics
by Duane E. HainesIt is not the goal of the present volume to promote Galago as an animal model, but to alert investigators to the potential thereof. In this respect, this collection of papers serves as a general introduction. The subjects covered are purposefully broad so as to illustrate that Galago not only has been, but may be, utilized with success in a variety of research areas. Most papers deal with the pros and cons of utilizing Galago in a specific line of research and in many instances discuss potential problems which may arise. The established value of the lesser bushbaby in particular reseach endeavour is also discussed and illustrated by some contributors.
The Letters of Sigmund Freud and Otto Rank: Inside Psychoanalysis
by E. James Lieberman Gregory C. RichterSigmund Freud’s relationship with Otto Rank was the most constant, close, and significant of his professional life. Freud considered Rank to be the most brilliant of his disciples. The two collaborated on psychoanalytic writing, practice, and politics; Rank was the managing director of Freud’s publishing house; and after several years helping Freud update his masterpiece, The Interpretation of Dreams, Rank contributed two chapters. His was the only other name ever to be listed on the title page. This complete collection of the known correspondence between the two brings to life their twenty-year collaboration and their painful break.The 250 letters compiled by E. James Lieberman and Robert Kramer humanize and dramatize psychoanalytic thinking, practice, and organization from 1906 through 1925. The letters concern not just the work and trenchant contemporaneous observations of Freud and Rank but also their friendships, supporters, rivals, families, travels, and other personal and professional matters. Most interestingly, the letters trace Rank’s growing independence, the father-son schism over Rank’s "anti-Oedipal" heresy, his surprising reconciliation with Freud, and the moment when they parted ways permanently. A candid picture of how the pioneers of modern psychotherapy behaved with their patients, colleagues, and families—and each other—the correspondence between Freud and Rank demonstrates how psychoanalysis developed in relation to early twentieth-century science, art, philosophy, and politics.A rich primary source on psychiatry, history, and culture, The Letters of Sigmund Freud and Otto Rank is a cogent and powerful narrative of early psychoanalysis and its two most important personalities.
The Leucine Factor Diet: The Scientifically-proven Approach To Combat Sugar, Burn Fat And Build Muscle
by Victor PriskTHE ULTIMATE GUIDE TO THE POWERFUL AMINO ACID THAT SUPERCHARGES YOUR METABOLISM If your goal is to improve strength and vitality, sugar is the kryptonite that will hold you back. Fortunately, nature has provided the ultimate anti-sugar: leucine. This book reveals the amazing ability of leucine to combat the harmful effects of sugar, burn deep levels of fat and rapidly build muscle. With advice on getting started, building a personalized plan and successfully reaching your goals, The Leucine Factor Diet offers you a path for becoming healthy, strong and lean. Author Dr. Victor Prisk, an orthopedic surgeon, champion gymnast and bodybuilder, teaches how to optimize the leucine content of your food while creating nutritious and delicious meals. With detailed information on dietary supplements, resistance exercise and medical awareness, The Leucine Factor Diet brings together all the key elements to successful muscle building. Whether you are a competitive athlete or weekend warrior, this book has everything you need to take your fitness to the next level.
The Life Cycle of the Corpus Luteum
by Rina MeidanThe book is describes the life cycle of a unique endocrine gland that is absolutely essential for the establishment and maintenance of pregnancy in all mammalian species. The corpus luteum is unique because it is formed and destroyed every (non-fertile) reproductive cycle. When fertilization occurs, the corpus luteum is rescued or maintained. The processes that control corpus luteum formation, demise (luteolysis), or maintenance are just beginning to be unraveled in recent years; they involve diverse cell types and mechanisms. Some of these processes resemble tumor development--angiogenesis, for instance--but interestingly enough, this resemblance is only up to a point. The corpus luteum uses mechanisms that allow its normal, physiological growth and disappearance. Pulling together key research on the corpus luteum, this volume is of interest to both reproductive endocrinologists and comparative physiologists, with clinical relevance spanning comparative animal studies to women's health.
The Life Saver
by Lilian DarcyComing soon! The Life Saver by Lilian Darcy will be available Nov 1, 2016.
The Life You Save: Nine Steps to Finding the Best Medical Care-and Avoiding the Worst
by Patrick MalonePatient advocate Patrick Malone shows you how to get the best medical care and how to avoid being a victim of malpractice
The Life of Breath in Literature, Culture and Medicine: Classical to Contemporary (Palgrave Studies in Literature, Science and Medicine)
by David Fuller Jane Macnaughton Corinne SaundersThis open access book studies breath and breathing in literature and culture and provides crucial insights into the history of medicine, health and the emotions, the foundations of beliefs concerning body, spirit and world, the connections between breath and creativity and the phenomenology of breath and breathlessness. Contributions span the classical, medieval, early modern, Romantic, Victorian, modern and contemporary periods, drawing on medical writings, philosophy, theology and the visual arts as well as on literary, historical and cultural studies. The collection illustrates the complex significance and symbolic power of breath and breathlessness across time: breath is written deeply into ideas of nature, spirituality, emotion, creativity and being, and is inextricable from notions of consciousness, spirit, inspiration, voice, feeling, freedom and movement. The volume also demonstrates the long-standing connections between breath and place, politics and aesthetics, illuminating both contrasts and continuities.
The Life of Your Choice: Moving from ''Oh, No!'' to ''Oh, Wow!''
by Daniel BaxA remarkable story of recovering from a shattering accident—and how the author achieved what others said was impossible.This is the story of a man who miraculously woke up after a catastrophic accident left him unable to talk or eat, with his left side completely paralyzed, and with no memories of his past or who he was. He spent the next five years piecing together his past and relearning how to speak, eat, and walk—all things the doctors had assured his family he would never do again.This book gives us his story and the methods he used to achieve what conventional wisdom said was impossible—and serves as an inspiring, helpful guide for readers who want to replicate his success in their own lives.
The Life of a Medical Officer in World War I: The Experiences of Captain Harry Gordon Parker
by Lorraine EvansThe Life of a Medical Officer in WW1 documents the experiences of Captain Harry Gordon Parker and provides a rare insight into the conflict that engulfed Europe from 1914-1918. Having joined the Naval Medical Service as a Royal Navy Temporary Surgeon, Parker's first taste of war was aboard a hospital evacuation ship, which regularly crossed the English Channel, from Southampton to France, picking up casualties from the battle grounds. Somewhat disillusioned with the whole experience, he requested a transfer to the Royal Medical Army Corps and soon found himself transported to the trenches in France. It was here, first serving with the Lancashire Fusiliers and then later as permanent Regimental Medical Officer with the 2nd Manchester’s Regiment, that he spent the remainder of the war, witnessing first-hand the horrors of Passchendaele, Arras and the Somme. Parker's account not only reveals a record of the conflict, but also encompasses a totality of military life as it impacted on the medical fraternity. From bureaucratic red tape, lack of medical supplies, lice infestations, trench foot and absurd missions where the incompetence of his own side was as dangerous as the enemy, his thoughts are penned with sincerity, the utmost compassion as well as a certain degree of sardonic humor: ‘We went into the trenches for the first time at Givenchy. It snowed heavily, and our rations did not arrive. The Royal Welsh, however, generously shared their rations with our men, who repaid the kindness by (accidentally) shooting one of the Sergeants through the stomach!’. With endorsement from family members, author Lorraine Evans has revised Parker’s notes and scribblings for clarity and added complementary text to provide historical background. What transpires is a lasting and classic chronicle, an extraordinary human account of history as it ensued.
The Lifestyle Medicine Toolbox: Mind-Body Approaches for Health Promotion
by Ziya Altug, OCSThis holistic guide provides an integrative toolbox on how healthcare and fitness professionals can promote lifestyle medicine with their clients. Its clinical and evidence-informed approach focuses on the six primary lifestyle medicine factors: nutrition, exercise, sleep hygiene, stress management, risky substance use, and social connectedness. Each factor is enriched with a variety of strategies and advice including anti-inflammatory recipes, self-guided visualisation, tips on how to break bad habits, sustainable fitness, and mind-body exercises.Based on the author's 30+ years of experience as a trained physical therapist treating musculoskeletal conditions, this book's nonpharmacological and nonsurgical focus allows clients to feel empowered in taking charge of their health through a plethora of resources and techniques. It provides clear, actionable steps and real-world examples in order to nurture sustainable changes that promote long-term health and healing.
The Light Within: The Extraordinary Friendship of a Doctor and Patient Brought Together by Cancer
by Lois M. Ramondetta Deborah Rose SillsThe luminous true story of a friendship that shed the boundaries of the doctor-patient relationship and became less a confrontation with death than a celebration of the joys of life When young gynecologic oncology fellow Lois Ramondetta was first summoned to the room of a new patient, neither she nor the forty-nine-year-old professor of religion she encountered named Deborah Sills thought they had much in common. They certainly had no idea that they were about to embark on a transcendent odyssey that would become a soul-deep friendship. Now their heartfelt story, The Light Within, follows these two women through a decade of friendship and "big lives"—husbands, children, friends, and careers—ultimately crossing the country and traveling to foreign lands, where they spoke and wrote together about the intersection of doctors, patients, and spirituality. Both women searched together and openly for answers with honesty and intimacy until Deborah passed away in the spring of 2006.
The Liminal People
by Ayize Jama-EverettWhen his ex asks for help, Taggert risks the wrath of his enigmatic master to try and save her daughter. But as Taggert realizes the girl has more power than even he can imagine, he has to delve into the very nature of own skills and utilize his heart and soul to survive. Ayize Jama-Everett was born and raised in Harlem, New York. He has traveled in Northern Africa, New Hampshire, and northern California. He holds a master's degree in clinical psychology and a master's in divinity. When not educating or studying, he's usually enjoying aged rums and practicing his aim.
The Limits and Lies of Human Genetic Research: Dangers For Social Policy (Reflective Bioethics)
by Jonathan Michael KaplanIn The Limits and Lies of Human Genetic Research, Jonathan Kaplan weighs in on the controversial subject of the roles genes play in determining aspects of physical and behavioral human variation. Limits and Lies makes the case that neither the information we have on genes, nor on the environment, is sufficient to explain the complex variations among humans.