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Xenopus Protocols

by Stefan Hoppler Peter D Vize

During the 20th century Xenopus has flourished as an accessible experimental model system for studying vertebrate biology. The second edition of Xenopus Protocols:Post-Genomic Approaches expands upon the previous edition with novel approaches inspired by Xenopus tropicalis and the sequencing of its genome. Xenopus tropicalis genomics and tractable genetics combined with the unique experimental advantages of Xenopus laevis and their distinctive phylogenetic position make them unique model systems for vertebrate embryonic development in the 21st century. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Xenopus Protocols: Post-Genomic Approaches, Second Edition provides a toolkit that will enable every laboratory to maximize the power of this extraordinary experimental system in the post-genomic age.

Xenotransplantation: Science, Ethics, and Public Policy

by Committee on Xenograft Transplantation: Ethical Issues Public Policy

Xenotransplantation involves the transplantation of cells, tissues, and whole organs from one species to another. Interest in animal-to-human xenotransplants has been spurred by the continuing shortage of donated human organs and by advances in knowledge concerning the biology of organ and tissue rejection. The scientific advances and promise, however, raise complex questions that must be addressed.This book considers the scientific and medical feasibility of xenotransplantation and explores the ethical and public policy issues surrounding the possibility of renewed clinical trials. The volume focuses on the science base of xenotransplantation, public health risks of infectious disease transmission, and ethical and public policy issues, including the views of patients and their families.

Xenotransplantation: Ethical, Regulatory, and Social Aspects

by Daniel J. Hurst Luz Padilla Wayne D. Paris

This is the first volume to comprehensively discuss the ethical, regulatory, and social aspects of xenotransplantation research.Organized into four parts, Xenotransplantation begins by examining ethical issues around informed consent of the potential xenograft recipient, the major ethical issues encountered when doing this research on pigs, and allocation issues. Part two examines regulatory aspects from a global perspective, specifically from three major regions of the world doing xenotransplantation research currently, of which include the United States, Western Europe, and Asia. Following this, part three describes religious aspects of xenotransplantation amongst the major world religions, including Christianity, Islam, Judaism, and Hinduism. The book closes with an analysis of quantitative and qualitative studies conducted by the editors that assess the public’s perception of xenotransplantation. Featuring original data collected by the editors, this book is an instrumental resource for all clinicians involved in the research and practice of xenotransplantation.

Xenotransplantation and Risk: Regulating a Developing Biotechnology

by Sara Fovargue

Some developing biotechnologies challenge accepted legal and ethical norms because of the risks they pose. Xenotransplantation (cross-species transplantation) may prolong life but may also harm the xeno-recipient and the public due to its potential to transmit infectious diseases. These trans-boundary diseases emphasise the global nature of advances in health care and highlight the difficulties of identifying, monitoring and regulating such risks and thereby protecting individual and public health. Xenotransplantation raises questions about how uncertainty and risk are understood and accepted, and exposes tensions between private benefit and public health. Where public health is at risk, a precautionary approach informed by the harm principle supports prioritising the latter, but the issues raised by genetically engineered solid organ xenotransplants have not, as yet, been sufficiently discussed. This must occur prior to their clinical introduction because of the necessary changes to accepted norms which are needed to appropriately safeguard individual and public health.

Xerostomia: An Interdisciplinary Approach to Managing Dry Mouth

by Sarah Ginsberg

An interdisciplinary textbook on dry mouth, Xerostomia: An Interdisciplinary Approach to Managing Dry Mouth provides an overview of xerostomia for physicians, dentists, nurses, speech-language pathologists, and otolaryngologists who encounter the condition in their practice. Xerostomia is a common condition, yet only one in seven cases are referred to a speech-language pathologist or otolaryngologist for treatment. Featuring contributions from speech-language pathologists, otolaryngologists, dentists, oral pathologists, and nurses, the text’s interdisciplinary approach and evidence-based framework provides practitioners with an awareness and understanding of xerostomia that will improve interprofessional coordination and enhance patient care. With a robust accompanying website including patient education resources, Xerostomia addresses the following topics: An otolaryngologist’s view of xerostomia, including causes, symptoms, evaluation, and treatment Patient perspectives of living with xerostomia, including quality of life measures and new research findings Effect of xerostomia on dental and oral health Voice disorders associated with xerostomia Impact of xerostomia on swallowing The science of saliva, including composition and production Pharmacological management of xerostomia Xerostomia: An Interdisciplinary Approach to Managing Dry Mouth provides indispensable information for general practitioners, internists, dentists, nurses, otolaryngologists, speech-language pathologists, and speech-language pathology students, as well as any health care practitioners who encounter patients with xerostomia.

Xie's Chinese Veterinary Herbology

by Huisheng Xie Vanessa Preast

Xie's Chinese Veterinary Herbology serves as a practical guide to the theory and application of Chinese Herbal Medicine into veterinary practices. Divided into three parts, the book covers herbal materia medica used in treating various disorders and diseases, herbal formulas, and the clinical application of treatments. The book also outlines each herb's history, the formulation of herbal recipes, energetic actions, indications and contraindications of each formula, dosages, and clinical and pharmacological studies performed with herbal treatments. This text serves as an invaluable reference to veterinarians looking to expand treatment options.

Xie's Veterinary Acupuncture

by Huisheng Xie Vanessa Preast

Traditional Chinese Veterinary Medicine has been used to treat animals in China for thousands of years. Until now, the majority of the literature on Traditional Chinese Veterinary Medicine has been written in Chinese. Xie's Veterinary Acupuncture serves as a comprehensive and accessible reference on the basic principles, techniques and clinical application of veterinary acupuncture. Written by a world renowned authority on veterinary acupuncture and a panel of experts, the book incorporates a traditional Chinese approach to veterinary acupuncture, including ancient and newly developed acupuncture techniques for both small and large animals. With the growing interest in veterinary acupuncture worldwide, this ground-breaking and authoritative text is a timely resource for practitioners and students alike.

XIIIth International Symposium on Spermatology

by Lars Björndahl John Flanagan Rebecka Holmberg Ulrik Kvist

These proceedings of the 2018 XIII International Symposium on Spermatology focus on comparative biology, and encourages discussion and the exchange of ideas. The aim of this Symposium was to provide a unique opportunity and bring together scientists from a wide spectrum of research fields – human, domestic animals and other mammals, vertebrates, insects, and plants. The underlying focus is on the function of the spermatozoon – a common feature for sexual reproduction, but extremely varied. By exploring the variability, a better understanding of male reproductive functions can develop. These proceedings address the mechanisms of physiology and pathophysiology, rather than diagnosis and treatment. The symposium featured keynote lectures by invited speakers, followed by presentations on specific aspects of the general topic of the session. Experimental studies are given priority over clinical studies of patient populations. The proceedings comprise both keynote speakers' texts and selected free communications. Posters were considered for publication in the proceedings, and the volume includes exhibited materials on the work of prominent spermatologists, highlighting their important past achievements in the field.

XLV Mexican Conference on Biomedical Engineering: Proceedings of CNIB 2022, 6–8 October, Puerto Vallarta, México (IFMBE Proceedings #86)

by Dora-Luz Flores Citlalli Jessica Trujillo-Romero Rafael Gonzalez-Landaeta Christian Chapa-González Guadalupe Dorantes-Méndez J. J. Agustin Flores Cuautle Martha R. Ortiz-Posadas Ricardo A. Salido Ruiz Esmeralda Zuñiga-Aguilar

This book reports on fundamental research, cutting-edge technologies and industrially-relevant applications in biomedical engineering. It covers methods for analysis, modeling and simulation of biological systems, reporting on the development and design of advanced biosensors, nanoparticles and wearable devices. It covers applications in disease monitoring and therapy, tissue engineering, sport and rehabilitation, and telehealth. It also reports on engineering methods for improving and monitoring medical service, and on advanced robotic applications. Gathering the proceedings of the XLV Congreso Nacional de Ingeniería Biomédica (CNIB2022), organised by the Mexican Society of Biomedical Engineering, this book offers a timely snapshot on technologies and methods in bioengineering, and on challenges related to their practical implementation in the health sector.

XLVI Mexican Conference on Biomedical Engineering: Proceedings of CNIB 2023, November 2–4, 2023, Villahermosa Tabasco, México - Volume 1: Signal Processing And Bioinformatics (IFMBE Proceedings #96)

by José de Jesús Agustín Flores Cuautle Balam Benítez-Mata Ricardo Antonio Salido-Ruiz Gustavo Adolfo Alonso-Silverio Guadalupe Dorantes-Méndez Esmeralda Zúñiga-Aguilar Hugo A. Vélez-Pérez Edgar Del Hierro-Gutiérrez Aldo Rodrigo Mejía-Rodríguez

This book reports on cutting-edge research and best practices in the broad fiel of biomedical engineering. Based on the XLVI Mexican Congress on Biomedical Engineering, CNIB 2023, held on November 2-4, 2023 in Villahermosa Tabasco, Mexico, this first volume of the proceedings covers research topics in biomedical signals and image processing, artificial intelligence, biosensors, and wearable systems, with applications ranging from disease classification and diagnosis, to health monitoring and medical therapy. All in all, this book provides a timely snapshot on state-of-the-art achievements in biomedical engineering and current challenges in the field. It addresses both researchers and professionals, and it is expect to foster future collaborations between the two groups, as well as international collaborations..

XLVI Mexican Conference on Biomedical Engineering: Proceedings of CNIB 2023, November 2–4, 2023, Villahermosa Tabasco, México - Volume 2: Biomechanics, Rehabilitation and Clinical Engineering (IFMBE Proceedings #97)

by José de Jesús Agustín Flores Cuautle Balam Benítez-Mata Ricardo Antonio Salido-Ruiz Gustavo Adolfo Alonso-Silverio Guadalupe Dorantes-Méndez Esmeralda Zúñiga-Aguilar Hugo A. Vélez-Pérez Edgar Del Hierro-Gutiérrez Aldo Rodrigo Mejía-Rodríguez

This book reports on cutting-edge research and best practices in the broad fiel of biomedical engineering. Based on the XLVI Mexican Congress on Biomedical Engineering, CNIB 2023, held on November 2-4, 2023 in Villahermosa Tabasco, Mexico, this second volume of the proceedings covers research topics in biomechanics, materials and engineering design and manufacturing, with applications in prostheses design and development, tissue engineering, medical device assessment and healthcare management. All in all, this book provides a timely snapshot on state-of-the-art achievements in biomedical engineering and current challenges in the field. It addresses both researchers and professionals, and it is expect to foster future collaborations between the two groups, as well as international collaborations. .

The XX Brain: The Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer's Disease

by Lisa Mosconi

"In The XX Brain, Lisa meticulously guides us in the ways we can both nourish and protect ourselves, body and mind, to ensure our brains remain resilient throughout our lives."--from the foreword by Maria ShriverThe first book to address cognitive enhancement and Alzheimer's prevention specifically in women--and to frame brain health as an essential component of Women's Health.In this revolutionary book, Dr. Lisa Mosconi, director of the Women's Brain Initiative at Weill Cornell Medical College, provides women with the first plan to address the unique risks of the female brain.Until now, medical research has focused on "bikini medicine," assuming that women are essentially men with breasts and tubes. Yet women are far more likely than men to suffer from anxiety, depression, migraines, brain injuries, and strokes. They are also twice as likely to end their lives suffering from Alzheimer's disease, even when their longer lifespans are taken into account. But in the past, the female brain has received astonishingly little attention and was rarely studied by medical researchers-- resulting in a wealth of misinformation about women's health.The XX Brain confronts this crisis by revealing how the two powerful X chromosomes that distinguish women from men impact the brain first and foremost and by focusing on a key brain-protective hormone: estrogen.Taking on all aspects of women's health, including brain fog, memory lapses, depression, stress, insomnia, hormonal imbalances, and the increased risk of dementia, Dr. Mosconi introduces cutting-edge, evidence-based approaches to protecting the female brain, including a specific diet proven to work for women, strategies to reduce stress, and useful tips for restorative sleep. She also examines the controversy about soy and hormonal replacement therapy, takes on the perils of environmental toxins, and examines the role of our microbiome. Perhaps best of all, she makes clear that it is never too late to take care of yourself.The XX Brain is a rallying cry for women to have full access to information regarding what is going on in their brains and bodies as well as a roadmap for the path to optimal, lifelong brain health.

XXVI Brazilian Congress on Biomedical Engineering: CBEB 2018, Armação de Buzios, RJ, Brazil, 21-25 October 2018 (Vol. 1) (IFMBE Proceedings #70/1)

by Rodrigo Costa-Felix João Carlos Machado André Victor Alvarenga

This volume presents the proceedings of the Brazilian Congress on Biomedical Engineering (CBEB 2018). The conference was organised by the Brazilian Society on Biomedical Engineering (SBEB) and held in Armação de Buzios, Rio de Janeiro, Brazil from 21-25 October, 2018. Topics of the proceedings include these 11 tracks: • Bioengineering • Biomaterials, Tissue Engineering and Artificial Organs • Biomechanics and Rehabilitation • Biomedical Devices and Instrumentation • Biomedical Robotics, Assistive Technologies and Health Informatics • Clinical Engineering and Health Technology Assessment • Metrology, Standardization, Testing and Quality in Health • Biomedical Signal and Image Processing • Neural Engineering • Special Topics • Systems and Technologies for Therapy and Diagnosis

XXVI Brazilian Congress on Biomedical Engineering: CBEB 2018, Armação de Buzios, RJ, Brazil, 21-25 October 2018 (Vol. 2) (IFMBE Proceedings #70/2)

by Rodrigo Costa-Felix João Carlos Machado André Victor Alvarenga

This volume presents the proceedings of the Brazilian Congress on Biomedical Engineering (CBEB 2018). The conference was organised by the Brazilian Society on Biomedical Engineering (SBEB) and held in Armação de Buzios, Rio de Janeiro, Brazil from 21-25 October, 2018.Topics of the proceedings include these 11 tracks:• Bioengineering• Biomaterials, Tissue Engineering and Artificial Organs• Biomechanics and Rehabilitation• Biomedical Devices and Instrumentation• Biomedical Robotics, Assistive Technologies and Health Informatics• Clinical Engineering and Health Technology Assessment• Metrology, Standardization, Testing and Quality in Health• Biomedical Signal and Image Processing• Neural Engineering• Special Topics• Systems and Technologies for Therapy and Diagnosis

YAC Protocols

by Alasdair Mackenzie

This completely revised and updated edition of YAC Protocols takes advantage of the many new advances in biology since the publication of the first edition, including the sequencing of the human genome, the genomes of a wide variety of other organisms, and the increased use of transgenic animals for understanding the molecular basis of human and animal disease. This volume also provides a much-needed update on the new techniques currently employed and to help redefine and illustrate the important roles still to be played by yeast artificial chromosome (YAC) technologies in the postgenomic age. YAC Protocols, Second Edition, demonstrates the enormous potential use of YAC technologies in understanding the role of genetics in maintaining health, promoting pathogenesis, and conferring susceptibility to disease. Offering solutions to the many problems that have plagued researchers, this new edition allows for the wider and more efficient use of YAC technologies for the analysis of genetic and pathogenic causes of human disease.

YAC Protocols

by David Markie

In YAC Protocols experienced researchers offer a comprehensive collection of their easily reproducible and proven methods for analyzing complex human, animal, and plant genomes. The step-by-step protocols cover all aspects of yeast artificial chromosomes, ranging from the construction of YAC libraries to their storage, screening, and database management, and to their use in such specialist applications as the transfer of YACs to mammalian cells and the isolation of coding sequences from YACs. YAC Protocols allows workers to add promising approaches adapted from yeast genetics to their personal repertoires and to introduce novel techniques emerging from the accumulating experience with YACs as a tool for genome analysis. Its extensive notes and background information not only significantly enhance the effective use of the methods, but also provide a valuable hands-on resource for those wishing to adapt protocols to suit their own applications.

Yaffe and Aranda's Neonatal and Pediatric Pharmacology: Therapeutic Principles in Practice

by Jacob V. Aranda

The premier comprehensive textbook in the field, Yaffe and Aranda’s Neonatal and Pediatric Pharmacology, Fifth Edition, provides an authoritative overview of all aspects of drug therapy in newborns, children, and adolescents. It offers evidence-based guidelines for safe, effective, and rational drug therapy, including specific recommendations for all major drug classes and diseases. Now in a vibrant two-color format, this fully revised reference is an indispensable resource for pediatricians, neonatologists, pediatric residents, and fellows in different pediatric subspecialties, including neonatal medicine and pediatric critical care.

The Yale Guide to Women's Reproductive Health: From Menarche to Menopause

by Mary Jane Minkin Carol V. Wright

This book is for every woman who has wished for an unhurried, personal conversation with a sympathetic doctor who will answer her questions about reproductive health. With warmth and understanding, the authors respond to questions about the gynecological issues that concern women today.

The Yale Pharyngeal Residue Severity Rating Scale

by Steven B. Leder Paul D. Neubauer

This text is a reliable, validated, anatomically defined, and image-based tool to determine residue location and severity when performing fiberoptic endoscopic evaluation of swallowing (FEES). Based upon research by Drs. Leder and Neubauer, an easily interpreted, readily learned, and hierarchically organized pharyngeal residue severity rating scale was developed for speech-language pathologists, otolaryngologists, and other health care professionals who perform and interpret FEES. The Yale Pharyngeal Residue Severity Rating Scale works equally well for any swallow of interest, whether it is the first, subsequent clearing, or last swallow. The endoscopist simply has to match their chosen swallow with its scale mate. The Yale Pharyngeal Residue Severity Rating Scale can be used for both clinical advantages and research opportunities. Clinically, clinicians can now accurately classify vallecula and pyriform sinus residue severity as none, trace, mild, moderate, or severe for diagnostic purposes, determination of functional therapeutic change, and precise dissemination of shared information. Research uses include tracking outcomes for clinical trials, investigating various swallowing interventions, demonstrating efficacy of specific interventions to reduce pharyngeal residue, determining morbidity and mortality associated with pharyngeal residue in different patient populations, and improving the training and accuracy of FEES interpretation by students and clinicians. The Yale Pharyngeal Residue Severity Rating Scale is an important addition to the deglutologist's tool box.

The Yale Swallow Protocol

by Steven B. Leder Debra M. Suiter

The Yale Swallow Protocol is an evidence-based protocol that is the only screening instrument that both identifies aspiration risk and, when passed, is able to recommend specific oral diets without the need for further instrumental dysphagia testing. Based upon research by Drs. Steven B. Leder and Debra M. Suiter, an easily administered, reliable and validated swallow screening protocol was developed and can be used by speech-language pathologists, nurses, otolaryngologists, oncologists, neurologists, intensivists and physicians assistants. In addition, the protocol can be used in a variety of environments, including acute care, rehabilitation and nursing homes. The Yale Swallow Protocol meets all of the criteria necessary for a successful screening test, including being simple to administer, cross-disciplinary, cost effective, acceptable to patients and able to identify the target attribute by giving a positive finding when aspiration risk is present and a negative finding when aspiration risk is absent. Additionally, early and accurate identification of aspiration risk can significantly reduce health-care costs associated with recognized prandial aspiration.

Yamada's Atlas of Gastroenterology

by Fergus Shanahan J. Gregory Fitz Timothy C. Wang Daniel K. Podolsky Michael Camilleri Anthony N. Kalloo

Access to accurate, high-quality images is vital for ensuring effective management of patients with GI complaints. The fifth edition of Yamada's Atlas of Gastroenterology sees the return of the gold-standard multi-media atlas that provides gastroenterologists with an outstanding visual tool covering all facets of the field. Every GI disorder from liver abscesses, endocrine neoplasms of the pancreas, to motility disorders of the esophagus are fully illustrated through the use of endoscopic ultrasonographs, computed tomography scans, magnetic resonance images, radionuclide images, and angiograms.

Yamada's Atlas of Gastroenterology

by Timothy C. Wang Michael Camilleri Benjamin Lebwohl Kenneth K. Wang Anna S. Lok Gary D. Wu William J. Sandborn

YAMADA’S Atlas of Gastroenterology Gastroenterology and Hepatology remain highly visual specialties, in part because of the tremendous accessibility of the luminal gastrointestinal tract to endoscopic examination and biopsy, and other internal digestive organs to advanced imaging modalities and sampling. Thus, in addition to standard views of cross-sectional imaging and histopathologic analysis used in many disorders, the field encompasses multimodal endoscopic imaging, which has continued to advance over the last decade. This sixth edition of Yamada’s Atlas of Gastroenterology continues to offer diverse images that provide an overview of the field of digestive diseases, and aims to provide a synopsis through pictures and illustrations rather than through text. Consequently, this Atlas is designed to complement and accompany the primary textbook in the field, the seventh edition of Yamada’s Textbook of Gastroenterology. This newest edition of the Atlas presents a wealth of pictorial material designed to provide a highly informative snapshot of major gastrointestinal, pancreatic and hepatobiliary diseases. Every GI disorder from liver abscesses, endocrine neoplasms of the pancreas, to motility disorders of the esophagus are fully illustrated through the use of endoscopic and transabdominal ultrasonographs, computed tomography scans, magnetic resonance images, radionuclide images, angiograms, and high resolution manometry, in addition to histopathology and cytology. The Atlas includes over 2000 exceptional images, organized by disease entity and therapeutic modality, including histopathology slides, MRI and CT scans, endoscopy, EUS, and open surgery images. Boasting an outstanding editorial team and 200 chapter authors, who are internationally renowned experts in their fields of expertise, Yamada’s Atlas of Gastroenterology is designed for a wide spectrum of readers, including students, residents, fellows and other trainees, practicing clinicians, professors and related specialists. For a busy trainee or clinician seeking a quick introduction to the spectrum of GI diseases, Yamada’s Atlas of Gastroenterology represents a practical and useful introduction to important disorders, and brings to life the salient points of the topic accurately and comprehensively.

Yamada's Handbook of Gastroenterology

by John M. Inadomi Renuka Bhattacharya Joo Ha Hwang Cynthia Ko

This 4th edition of Yamada's Handbook of Gastroenterology provides a portable, well-illustrated, rapid access handbook for gastroenterologists of all levels, perfect for quick and easy use while on the wards. Divided into 2 parts -- part 1 being symptom-focused and part 2 disease-focused, it gives 100% clinical assessment and practical management advice for the entire range of GI symptoms, complaints and conditions that patients present with. Every symptom you're likely to encounter is covered, every condition assessed.

Yamada's Handbook of Gastroenterology

by Tadataka Yamada Jason A. Dominitz Renuka Bhattacharya Joo Ha Hwang John M. Inadomi

Portable, practical, and entirely clinical, this affordable guide to assessment and management of the entire range of gastroenterological complaints and conditions is ideally suited for use by GI fellows and specialists. The book is divided into two parts: symptom-focused and disease-focused. Features include key practice points, essentials of diagnosis, potential pitfalls, key web links, society guideline comparisons, case studies, and multiple choice questions. When you need answers in a hurry, turn to the most trusted name in gastroenterology: Yamada.

Yamada's Textbook of Gastroenterology

by Anna S. Lok Benjamin Lebwohl Kenneth K. Wang Gary D. Wu William J. Sandborn

YAMADA’S Textbook of Gastroenterology For over 25 years, Yamada’s Textbook of Gastroenterology has been the most comprehensive gastroenterology reference book, combining an encyclopedic basic science approach to GI and liver disease with the latest clinical thinking, especially in diagnostic and therapeutic developments. It is universally respected across the globe. The original outstanding editorial team was led by Tadataka Yamada, MD, one of the world’s leading figures in GI research. This seventh edition of the Textbook features a new set of Editors-in-Chief and a new team of Associate Editors. This new editorial team has made substantial changes and updates to the Textbook, with a greater focus on the human microbiome, obesity, bariatric endoscopy and aging, along with consolidation of many older chapters. Led by Professor Michael Camilleri and Professor Timothy C. Wang, a stellar group of associate editors have once again combined with authors in their respective fields to communicate their vast fund of knowledge and experience to make the 7th edition of this iconic textbook the most comprehensive ever published.

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