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Vaccinophobia and Vaccine Controversies of the 21st Century
by Archana ChatterjeeVaccinophobia and Vaccine Controversies of the 21st Century Archana Chatterjee, editor Once hailed as a medical miracle, vaccination has come under attack from multiple fronts, including occasionally from within medicine. And while the rates of adverse reactions remain low, suggestions that vaccines can cause serious illness (and even death) are inspiring parents to refuse routine immunizations for their children--ironically, exposing them and others to potentially serious illness. Vaccinophobia and Vaccine Controversies of the 21st Century explains clearly how this state of affairs came into being, why it persists, and how healthcare professionals can best respond. Current findings review answers to bedrock questions about known adverse events, what vaccine additives are used for, and real and perceived risks involved in immunization. Perspectives representing pediatricians, family practitioners, nurses, parents, pharmacy professionals, the CDC, and the public health community help the reader sort out legitimate from irrational concerns. In-depth analyses discuss the possibility of links with asthma, cancer, Guillain-Barre syndrome, SIDS, and, of course, autism. Included in the coverage: Communicating vaccine risks and benefitsThe vaccine misinformation landscape in family medicinePerceived risks from live viral vaccinesThe media's role in vaccine misinformationAutoimmunity, allergies, asthma, and a relationship to vaccinesVaccines and autism: the controversy that won't go awayThe conundrums described here are pertinent to practitioners in pediatrics, family medicine, primary care, and nursing to help families with informed decision making. In addition, Vaccinophobia and Vaccine Controversies of the 21st Century should be read by trainees and researchers in child development and maternal and child health as the book's issues will have an impact on future generations of children and their families.
The Vagina Bible: The Vulva and the Vagina: Separating the Myth from the Medicine
by Dr. Jen GunterInstant New York Times, USA Today, and Publishers Weekly bestseller!Boston Globe bestseller#1 Canadian BestsellerOB/GYN, The New York Times columnist, host of the show Jensplaining, and internationally bestselling author Dr. Jen Gunter now delivers the definitive book on vaginal health, answering the questions you&’ve always had but were afraid to ask—or couldn&’t find the right answers to. She has been called Twitter&’s resident gynecologist, the Internet&’s OB/GYN, and one of the fiercest advocates for women&’s health…and she&’s here to give you the straight talk on the topics she knows best. Does eating sugar cause yeast infections? Does pubic hair have a function? Should you have a vulvovaginal care regimen? Will your vagina shrivel up if you go without sex? What&’s the truth about the HPV vaccine? So many important questions, so much convincing, confusing, contradictory misinformation! In this age of click bait, pseudoscience, and celebrity-endorsed products, it&’s easy to be overwhelmed—whether it&’s websites, advice from well-meaning friends, uneducated partners, and even healthcare providers. So how do you separate facts from fiction? OB-GYN Jen Gunter, an expert on women&’s health—and the internet&’s most popular go-to doc—comes to the rescue with a book that debunks the myths and educates and empowers women. From reproductive health to the impact of antibiotics and probiotics, and the latest trends, including vaginal steaming, vaginal marijuana products, and jade eggs, Gunter takes us on a factual, fun-filled journey. Discover the truth about: • The vaginal microbiome • Genital hygiene, lubricants, and hormone myths and fallacies • How diet impacts vaginal health • Stem cells and the vagina • Cosmetic vaginal surgery • What changes to expect during pregnancy and after childbirth • What changes to expect through menopause • How medicine fails women by dismissing symptomsPlus: • Thongs vs. lace: the best underwear for vaginal health • How to select a tampon • The full glory of the clitoris and the myth of the G Spot . . . And so much more. Whether you&’re a twenty-six-year-old worried that her labia are &“uncool&” or a sixty-six-year-old dealing with painful sex, this comprehensive guide is sure to become a lifelong trusted resource.
The Vagina Bible: The vulva and the vagina--separating the myth from the medicine
by Jen GunterFrom Canadian OB/GYN, women's health advocate and New York Times columnist Dr. Jen Gunter: The Vagina Bible is a comprehensive, accessible antidote to the maelstrom of misinformation around female sexual health, and the ultimate guide to everything a person needs to know about the vagina and vulva.We are well into the twenty-first century and have access to more information than ever before, yet many people don't know that a vagina is self-cleaning, condoms should be used with a lubricant, eating sugar doesn't cause a yeast infection, and sex shouldn't be painful. As a physician with twenty-five years of clinical experience, Dr. Jen Gunter is all too familiar with the fears, fallacies and misinformation that abound about vaginal health. On Twitter, she hilariously exposes unscientific wellness advice and debunks potentially harmful and stunningly unnecessary products from "vagina profiteers." Dr. Gunter knows the questions women (and men) have about female sexual health, and in The Vagina Bible, she answers them all. For: * the sixteen-year-old trying to figure out tampons; * the twenty-six-year-old wondering how to avoid a UTI; * the thirty-six-year-old trans woman navigating her new anatomy; * the forty-six-year-old worried about the changing appearance of her vulva; * the fifty-six-year-old looking into the HPV vaccine for her daughter (and maybe herself); * the sixty-six-year-old experiencing painful sex;The Vagina Bible offers a repository of accurate information based on science, and delivered with wit and wisdom. This is the fact-based, inclusive, and empowering guide you deserve to advocate for your own body.
The Vagina Monologues (10th Anniversary Edition)
by Eve Ensler"I was worried about vaginas. I was worried about what we think about vaginas, and even more worried that we don't think about them... So I decided to talk to women about their vaginas, to do vagina interviews, which became vagina monologues. I talked with over two hundred women. I talked to old women, young women, married women, single women, lesbians, college professors, actors, corporate professionals, sex workers, African American women, Hispanic women, Asian American women, Native American women, Caucasian women, Jewish women. At first women were reluctant to talk. They were a little shy. But once they got going, you couldn't stop them." So begins Eve Ensler's hilarious, eye-opening tour into the last frontier, the forbidden zone at the heart of every woman. Adapted from the award-winning one-woman show that's rocked audiences around the world, this groundbreaking book gives voice to a chorus of lusty, outrageous, poignant, and thoroughly human stories, transforming the question mark hovering over the female anatomy into a permanent victory sign. With laughter and compassion, Ensler transports her audiences to a world we've never dared to know, guaranteeing that no one who reads The Vagina Monologues will ever look at a woman's body the same way again.
Vagina Obscura: An Anatomical Voyage
by Rachel E. GrossA myth-busting voyage into the female body. A camera obscura reflects the world back but dimmer and inverted. Similarly, science has long viewed woman through a warped lens, one focused narrowly on her capacity for reproduction. As a result, there exists a vast knowledge gap when it comes to what we know about half of the bodies on the planet. That is finally changing. Today, a new generation of researchers is turning its gaze to the organs traditionally bound up in baby-making—the uterus, ovaries, and vagina—and illuminating them as part of a dynamic, resilient, and ever-changing whole. Welcome to Vagina Obscura, an odyssey into a woman’s body from a fresh perspective, ushering in a whole new cast of characters. In Boston, a pair of biologists are growing artificial ovaries to counter the cascading health effects of menopause. In Melbourne, a urologist remaps the clitoris to fill in crucial gaps in female sexual anatomy. Given unparalleled access to labs and the latest research, journalist Rachel E. Gross takes readers on a scientific journey to the center of a wonderous world where the uterus regrows itself, ovaries pump out fresh eggs, and the clitoris pulses beneath the surface like a shimmering pyramid of nerves. This paradigm shift is made possible by the growing understanding that sex and gender are not binary; we all share the same universal body plan and origin in the womb. That’s why insights into the vaginal microbiome, ovarian stem cells, and the biology of menstruation don’t mean only a better understanding of female bodies, but a better understanding of male, non-binary, transgender, and intersex bodies—in other words, all bodies. By turns funny, lyrical, incisive, and shocking, Vagina Obscura is a powerful testament to how the landscape of human knowledge can be rewritten to better serve everyone.
Vagina Problems: Endometriosis, Painful Sex, and Other Taboo Topics
by Lara Parker“In Vagina Problems…Lara Parker unpacks the personal and economic costs of endometriosis.” —Vanity Fair“A refreshingly honest read about living with chronic pain.” —Hello GigglesWith unflinching honesty, Lara Parker, the Deputy Director for BuzzFeed, shares her day-to-day challenges of living, working, and loving with chronic pain caused by endometriosis in this raw, darkly humorous, and hopeful memoir.I wasn’t ready to be completely honest about my vagina yet, and the world wasn’t ready for that either. But I was getting there. I wanted the world to know that all of this pain I had been feeling…that it was related to my vagina. Thus, Vagina Problems was born. It was a cutesy name. It was my way of taking this pain and saying, “Whatever. I’m here. I have it. It sucks. Let’s talk about it.”In April 2014, Deputy Editorial Director at BuzzFeed Lara Parker opened up to the world in an article on the website: she suffers from endometriosis. And beyond that? She let the whole world know that she wasn’t having any sex, as sex was excruciatingly painful. Less than a year before, she received not only the diagnosis of endometriosis, but also a diagnosis of pelvic floor dysfunction, vulvodynia, vaginismus, and vulvar vestibulitis. Combined, these debilitating conditions have wreaked havoc on her life, causing excruciating pain throughout her body since she was fourteen years old. These are her Vagina Problems. It was five years before Lara learned what was happening to her body. Five years of doctors insisting she just had “bad period cramps,” or implying her pain was psychological. Shamed and stigmatized, Lara fought back against a medical community biased against women and discovered that the ignorance of many doctors about women’s anatomy was damaging more than just her own life. One in ten women have endometriosis and it takes an average of seven years before they receive an accurate diagnosis—or any relief from this incurable illness’ chronic pain. With candid revelations about her vaginal physical therapy, dating as a straight woman without penetrative sex, coping with painful seizures while at the office, diet and wardrobe malfunctions when your vagina hurts all the time, and the depression and anxiety of feeling unloved, Lara tackles it all in Vagina Problems: Endometriosis, Painful Sex, and Other Taboo Topics with courage, wit, love, and a determination to live her best life.
Vaginal Hysterectomy
by Shirish S. Sheth Frcog Facs Fics Ficog Fcps Fams Fsogc John Studd DScIn recent years advances in laparoscopic technologies have led to renewed interest in the vaginal approach to hysterectomy, which has many proven benefits for patients. This volume, dedicated to explaining and promoting the vaginal route of hysterectomy, is written and edited by an international team of experts and provides a much-needed source of
Vaginal Pessaries
by Teresa Tam Matthew F. DaviesWith mesh surgery for prolapse sometimes proving problematic, there has been a resurgence of professional medical interest in more traditional methods for the management of prolapse and of stress urinary incontinence. This concise guide to the practical aspects of pessary use will be of interest to all gynecologists involved in the clinical management of the patient with these problems. Contents: Historical review * Pessaries for pelvic organ prolapse * Incontinence pessaries * Pessary fitting * Pessary care * Outcomes of pessary use * Current clinical studies on vaginal pessaries Cover image of vaginal pessaries © 2019 Rick Hicaro, Jr., Chicago, IL 60647, USA
The Vagus Nerve in Therapeutic Practice: Working with Clients to Manage Stress and Enhance Mind-Body Function
by Ann BaldwinThe Vagus Nerve in Therapeutic Practice describes practical, science-based techniques that can be used to improve vagal performance with the goal of restoring and maintaining mind-body health. Aimed at complementary medicine practitioners and holistic healers such as massage therapists, biofield practitioners, nutritional therapists, aromatherapists and energy healers, it explains how practitioners can adapt their modalities to stimulate the vagus nerve, together with other cranial nerves and the limbic system, to enhance their clients' experience and improve outcomes.The book provides a clear understanding of the importance and benefits of self-regulating the autonomic nervous system, focusing on the vagus nerve. This nerve controls the stress response, regulates digestion, modulates the immune system, and releases an anti-inflammatory neurotransmitter, acetylcholine; when it functions inadequately, all of these systems can be adversely affected. By learning techniques to stimulate the vagus nerve, practitioners can help those experiencing low-level inflammation and emotional stress, including those with chronic diseases. Each chapter provides practical, evidence-based methods that can be used to stimulate the ventral vagal complex, illustrated by a case history from a complementary medicine or holistic practice. The author addresses the anatomy and evolution of the vagus nerve, including its possible role in promoting social engagement, using the polyvagal theory as a model. The functions of major branches of the vagus nerve and other neighbouring cranial nerves are discussed in turn; in each case the mechanism by which neural stimulation improves relaxation and health is outlined, and a practical way to engage the nerve branch and limbic system is described with the help of a case study. An addendum includes an easily referenced summary of the exercises described throughout the book, as well as routines for utilizing combinations of the exercises on a daily, weekly and monthly basis.This book will enable healthcare professionals to attain a solid grasp of the clinical significance of regulating the vagus nerve and provide them with simple ways to do it.
Vagus Nerve Stimulation (Neuromethods #205)
by Martin G. Frasch Eric C. PorgesThis volume covers the latest research and development in the areas of Vagus Nerve Stimulation (VNS) as it relates to bioelectronic medicine from neonate to adult. The chapters in this book cover topics such as invasive and non-invasive VNS including methodological considerations (study design, stimulation parameters, and use of heart rate variability metrics); mechanisms of action (automatic regulation and immune plasticity); and disorders where VNS approaches may be therapeutic (migraine and cluster headaches, mood disorders, trauma-related disorders, and language learning). In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.Comprehensive and thorough, Vagus Nerve Stimulation is a valuable resource for both novice and expert preclinical and clinical scientists, clinicians, physicians, and scholars who are interested in learning more about this exciting and developing field.
Vagus Nerve Stimulation
by James Robertson Claude Roux Kenneth G. WigginsThis second edition presents a timely and practical discussion of vagal nerve stimulation in a clear and well-illustrated format. It provides a clinical approach to the treatment of patients with medically-intractable seizures, as well as for those with depression (a new indication since the publication of first edition). The book's focus has made
Vakbekwaam indiceren: Een handreiking voor wijkverpleegkundigen
by Henk Rosendal José van DorstDit boek helpt bij het indiceren van ‘verpleging en verzorging zonder verblijf’. Het 7-stappenmodel zorgt ervoor dat er onderbouwd en transparant geïndiceerd wordt. Deze handreiking is bedoeld voor wijkverpleegkundigen en studenten verpleegkunde.Deze geheel herziene versie van Vakbekwaam Indiceren is overzichtelijker doordat stappen uit het 11-stappenmodel zijn samengevoegd. Het nieuwe 7-stappenmodel is ook in lijn met het verpleegkundig proces, de basis van verpleegkundig handelen. Hoewel in deze handreiking in eerste instantie is uitgegaan van Nanda-I, Noc en Nic, wordt per stap ook aangegeven hoe gebruikers van het Omaha-systeem hiermee om kunnen gaan.Aan de hand van het verpleegkundig proces worden de volgende stappen besproken: anamnese/assessment, verpleegkundige diagnoses, bepalen zorgresultaten, indiceren, organiseren/uitvoeren, monitoren/evalueren en borgen kwaliteit. Dit is de meest logische en meest gebruikte volgorde. Toch moet het in de praktijk wel eens anders. Daarom sluit het boek af met een hoofdstuk over een alternatieve werkwijze.Vakbekwaam Indiceren is geschreven door Henk Rosendal, lector De Gezonde Wijk bij Kenniscentrum Zorginnovatie van Hogeschool Rotterdam en José van Dorst, vakinhoudelijk manager bij TWB Thuiszorg met Aandacht.
The Valedictorian of Being Dead: The True Story of Dying Ten Times to Live
by Heather B. ArmstrongFrom New York Times bestselling author and blogger Heather B. Armstrong comes an honest and irreverent memoir—reminiscent of the New York Times bestseller Brain on Fire—about her experience as one of only a few people to participate in an experimental treatment for depression involving ten rounds of a chemically induced coma approximating brain death.For years, Heather B. Armstrong has alluded to her struggle with depression on her website, dooce. It’s scattered throughout her archive, where it weaves its way through posts about pop culture, music, and motherhood. But in 2016, Heather found herself in the depths of a depression she just couldn’t shake, an episode darker and longer than anything she had previously experienced. She had never felt so discouraged by the thought of waking up in the morning, and it threatened to destroy her life. So, for the sake of herself and her family, Heather decided to risk it all by participating in an experimental clinical trial involving a chemically induced coma approximating brain death. Now, for the first time, Heather recalls the torturous eighteen months of suicidal depression she endured and the month-long experimental study in which doctors used propofol anesthesia to quiet all brain activity for a full fifteen minutes before bringing her back from a flatline. Ten times. The experience wasn’t easy. Not for Heather or her family. But a switch was flipped, and Heather hasn’t experienced a single moment of suicidal depression since. Disarmingly honest, self-deprecating, and scientifically fascinating, The Valedictorian of Being Dead brings to light a groundbreaking new treatment for depression.
Valentino's Pregnancy Bombshell
by Amy AndrewsOne danceWhen Paige buttons up her silk bridesmaid dress she feels beautiful for the first time in years-giving her the courage to take deliciously dangerous Valentino Lombardi's hand on the dance floor.One kissPaige spends one incredible night with Valentino. Until the cold light of dawn reminds her she's a single mom with a daughter who really needs her care. As the sun rises she creeps away.One baby!Then Valentino arrives as the new surgeon at her hospital, with his playboy reputation in tow! But the bombshells don't stop there-now Paige must tell Valentino she's expecting his baby....
Validated Cleaning Technologies for Pharmaceutical Manufacturing
by Destin A. LeBlancWritten by an expert for those who must design validatable cleaning processes and then validate those processes, this book discusses interdependent topics from various technical areas and disciplines. It shows how each piece of the cleaning process fits into the validation program, making it more defensible in both internal quality audits and exter
Validating Medical Packaging
by Ronald PilchikAccording to the FDA Quality System Regulations, manufacturers must ensure that "device packaging and shipping containers are designed and constructed to protect the device from alteration or damage during the customary conditions of processing, storage, handling, and distribution." As specific as this statement is, the FDA does not provide instruc
Validating Neuro-Computational Models of Neurological and Psychiatric Disorders
by Basabdatta Sen Bhattacharya Fahmida N. ChowdhuryThis book is a collection of articles by leading researchers working at the cutting edge of neuro-computational modelling of neurological and psychiatric disorders. Each article contains model validation techniques used in the context of the specific problem being studied. Validation is essential for neuro-inspired computational models to become useful tools in the understanding and treatment of disease conditions. Currently, the immense diversity in neuro-computational modelling approaches for investigating brain diseases has created the need for a structured and coordinated approach to benchmark and standardise validation methods and techniques in this field of research. This book serves as a step towards a systematic approach to validation of neuro-computational models used for studying brain diseases and should be useful for all neuro-computational modellers.
Validation and Qualification in Analytical Laboratories
by Ludwig HuberThis Second Edition discusses ways to improve pharmaceutical product quality while achieving compliance with global regulatory standards. With comprehensive step-by-step instructions, practical recommendations, standard operating procedures (SOPs), checklists, templates, and graphics for easy incorporation in a laboratory. This title
The Validation Breakthrough: Simple Techniques for Communicating with People with Alzheimer's and Other Dementias, Third Edition
by Naomi Feil Vicki de Klerk-RubinValidation is a practical way of communicating with and managing problem behavior in older adults with Alzheimer's type dementia. It helps reduce stress, enhance dignity, and increase happiness. The Validation Breakthrough is an essential resource for all settings providing dementia care including assisted living facilities, nursing homes, skilled nursing facilities, hospice, home health care, adult day services, family care settings, and more.
Validation for Medical Device and Diagnostic Manufacturers
by Carol V. Desain Charmaine V. SuttonImplementation of FDA's Design Control requirements (21 CFR 820.30) changed an entire industry. Quality System Requirements defined the approach to medical device validation. Product design, manufacturing process, and test method validation studies must be performed before or as a product is transferred to commercial production. Validation studies
Validation of Alternative Methods for Toxicity Testing
by Chantra Eskes Maurice WhelanThis book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcriptomics, and for methods derived from pathway-based concepts in toxicology. Validation of Alternative Methods for Toxicity Testing is divided into two sections, in the first, practical insights are given on the state-of-the-art and on approaches that have resulted in successfully validated and accepted alternative methods. The second section focuses on the evolution of validation principles and practice that are necessary to ensure fit-for-purpose validation that has the greatest impact on international regulatory acceptance of alternative methods. In this context validation needs to keep pace with the considerable scientific advancements being made in toxicology, the availability of sophisticated tools and techniques that can be applied in a variety of ways, and the increasing societal and regulatory demands for better safety assessment. This book will be a useful resource for scientists in the field of toxicology, both from industry and academia, developing new test methods, strategies or techniques, as well as Governmental and regulatory authorities interested in understanding the principles and practicalities of validation of alternative methods for toxicity testing.
Validation of Bioanalytical Methods (essentials)
by Patric U. Vogelthis book, the validation of bioanalytical methods is described. In the quality control of biological medicinal products, bioanalytical methods are frequently used to check important properties such as the content or possible impurities. The methods used must provide trustworthy results so that no false conclusions are drawn when evaluating the results. The trustworthiness is ensured by validation. The validation of bioanalytical methods is illustrated by means of some examples.
Validation of Computerized Analytical Systems
by Ludwig HuberValidation of Computerized Analytical and Networked Systems provides the definitive rationales, logic, and methodology for validation of computerized analytical systems. Whether you are involved with formulation or analytical development laboratories, chemical or microbiological quality control laboratories, LIMS installations, or any aspect of robotic in a healthcare laboratory, this book furnishes complete validation details.International and FDA regulations and requirements are discussed and juxtaposed with numerous practical examples that show you how to cost-effectively and efficiently accomplish validation acceptable to FDA GCP/GLP/GMP, NAMAS, and EN45001 standards. The templates included provide documentation examples and the many checklists found throughout the book assure that all aspects of covered in a logical sequence. The chapters describe and explain such topics as the Product Life Cycle revalidation, change control, documentation requirements, qualifications, testing, data validation and traceability, inspection, SOPs, and many other that help streamline the validation process.
VALIDATION OF TOXICOGENOMIC TECHNOLOGIES: A Workshop Summary
by National Research Council of the National AcademiesBeginning in the early 1980s, new technologies, began to permit evaluation of the expression of individual genes. Recent technological advances have expanded those evaluations to permit the simultaneous detection of the expression of tens of thousands of genes and to support holistic evaluations of the entire genome. The application of these technologies has enabled researchers to unravel complexities of cell biology and, in conjunction with toxicologic evaluations, the technologies are used to probe and gain insight into questions of toxicologic relevance. As a result, the use of the technologies has become increasingly important for scientists in academia, as well as for the regulatory and drug development process.
Validierung bioanalytischer Methoden (essentials)
by Patric U. VogelIn diesem Buch wird die Validierung bioanalytischer Methoden beschrieben. Bei der Qualitätskontrolle von biologischen Arzneimitteln kommen häufig bioanalytische Methoden zum Einsatz, um wichtige Eigenschaften wie den Gehalt oder mögliche Verunreinigungen zu überprüfen. Die eingesetzten Methoden müssen vertrauenswürdige Ergebnisse liefern, damit bei der Bewertung der Ergebnisse keine falschen Schlüsse gezogen werden. Die Vertrauenswürdigkeit wird durch eine Validierung sichergestellt. Die Validierung von bioanalytischen Methoden wird anhand einiger Beispiele dargestellt.