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X-Ray Imaging Systems for Biomedical Engineering Technology: An Essential Guide
by Euclid SeeramThis book addresses X-Ray Imaging Systems intended for biomedical engineering technology students and practitioners, and deals with the major technical components of x-ray imaging modalities. These modalities include film-based imaging, digital radiography, and computed tomography. Furthermore, principles and concepts essential to the understanding of how these modalities function will be described. These include fundamental radiation physics, imaging informatics, quality control, and radiation protection considerations. X-Ray Imaging Systems for Biomedical Engineering Technology: An Essential Guide is intended for biomedical engineering technologists, who provide technical advice and services relating to digital radiography and CT departments not only in hospitals but in private facilities as well. Students in radiological technology programs may also find this to be a useful resource.
X-Ray Phase-Contrast Tomography: Underlying Physics and Developments for Breast Imaging (Springer Theses)
by Luca BrombalX-ray imaging is a corner stone of breast cancer diagnosis. By exploiting the phase shift of X-rays rather than their attenuation, phase-contrast tomography has the potential to dramatically increase the visibility of small and low contrast features, thus leading to better diagnosis. This thesis presents research on the first synchrotron-based project developing a clinical phase-contrast breast computed tomography (CT) setup at Elettra, the Italian Syncrotron Radiation Facility. This book includes a comprehensive theoretical background on propagation-based phase-contrast imaging, exploring and extending the most recent image formation models. Along with theory, many practical implementation and optimization issues, ranging from detector-specific processing to setup geometry, are tackled on the basis of a large number of experimental evidences. Most of the modelling results and data analysis have general validity, being a valuable framework for optimization of phase-contrast setups. Results obtained at synchrotron are also compared with "real world" laboratory sources: both a first-of-its-kind comparison with one of the few hospital breast CT systems and a state-of-the-art implementation of monochromatic phase-contrast micro-tomography with a conventional rotating anode source are presented. On a more general level, this work sheds a light on the importance of synchrotron-based clinical programs, which are key to trigger the long-anticipated transition of phase-contrast imaging from synchrotrons to hospitals.
X-Ray Spectroscopy with Synchrotron Radiation: Fundamentals and Applications (Biological and Medical Physics, Biomedical Engineering)
by Stephen P. CramerSynchrotron radiation has been a revolutionary and invaluable research tool for a wide range of scientists, including chemists, biologists, physicists, materials scientists, geophysicists. It has also found multidisciplinary applications with problems ranging from archeology through cultural heritage to paleontology. The subject of this book is x-ray spectroscopy using synchrotron radiation, and the target audience is both current and potential users of synchrotron facilities. The first half of the book introduces readers to the fundamentals of storage ring operations, the qualities of the synchrotron radiation produced, the x-ray optics required to transport this radiation, and the detectors used for measurements. The second half of the book describes the important spectroscopic techniques that use synchrotron x-rays, including chapters on x-ray absorption, x-ray fluorescence, resonant and non-resonant inelastic x-ray scattering, nuclear spectroscopies, and x-ray photoemission. A final chapter surveys the exciting developments of free electron laser sources, which promise a second revolution in x-ray science. Thanks to the detailed descriptions in the book, prospective users will be able to quickly begin working with these techniques. Experienced users will find useful summaries, key equations, and exhaustive references to key papers in the field, as well as outlines of the historical developments in the field. Along with plentiful illustrations, this work includes access to supplemental Mathematica notebooks, which can be used for some of the more complex calculations and as a teaching aid. This book should appeal to graduate students, postdoctoral researchers, and senior scientists alike.
Xcode 6 Essentials
by Jayant VarmaThis book is aimed at developers who want to make applications for Apple devices with Xcode. iOS developers who have experience using other frameworks and languages can now migrate to Xcode and build creative, native apps.
Xenobiotic Metabolic Enzymes: Bioactivation And Antioxidant Defense
by Chang-Hwei ChenThis book provides a comprehensive, organized, and concise overview of xenobiotic metabolic enzymes and their health implications. The subjects addressed are broad in scope with an emphasis on recent advances in research on biochemical and biomedical aspects of these enzymes. The xenobiotics discussed include not just drugs, but also food, smoke, and other environmental chemicals. The subjects covered in this work include: metabolic enzymes and their catalyzed reactions, reactive intermediates generated from metabolic activation, oxidative stress mediated by electrophilic reactive intermediates, bioactivation - mediated cellular and functional damages, activation of Nrf2 – ARE pathway, genetic variations affecting metabolic enzyme expression, enzyme polymorphisms affecting xenobiotic - mediated toxicity, induction of metabolic enzymes for health benefits, and a diversity of metabolic enzyme modulators.
Xenobiotic Metabolism and Disposition: The Design of Studies on Novel Compounds
by Harry P.A. IllingThis publication explains the principles of the techniques used in disposition and metabolism studies in animals, in man, and in vitro. It includes methods for studying routes and rates of absorption, distribution, metabolism, and excretion of novel compounds and their metabolites. Relevant surgical, whole-body autoradiographic and pharmacokinetic procedures are discussed, together with techniques for separating and identifying metabolites and metabolic path-ways. Information on when the procedures are appropriate, and examples of what they represent, are presented in order to illustrate the value of such studies.
Xenopus: Methods and Protocols (Methods in Molecular Biology #1865)
by Kris VleminckxThis volume explores techniques used to study and experiment with Xenopus in order to model or understand human disease. The chapters in this book cover topics such as implementation of CRISPR/Cas9 and TALEN in Xenopus from the design stage up to the genotyping stage; methods to explore generation of knock-in animals; cancer modelling and in vivo screening of congenital heart disease; electroporation; and phenotyping at the organismal level, cellular level, and proteome level. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Xenopus: Methods and Protocols is a valuable resource for researchers who are interested in expanding their knowledge of this wide and developing field. This book will aid in keeping Xenopus at the forefront for biochemical, cell biological, and developmental studies and forward it as a preclinical disease model.
Xenopus Protocols
by Stefan Hoppler Peter D VizeDuring the 20th century Xenopus has flourished as an accessible experimental model system for studying vertebrate biology. The second edition of Xenopus Protocols:Post-Genomic Approaches expands upon the previous edition with novel approaches inspired by Xenopus tropicalis and the sequencing of its genome. Xenopus tropicalis genomics and tractable genetics combined with the unique experimental advantages of Xenopus laevis and their distinctive phylogenetic position make them unique model systems for vertebrate embryonic development in the 21st century. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Xenopus Protocols: Post-Genomic Approaches, Second Edition provides a toolkit that will enable every laboratory to maximize the power of this extraordinary experimental system in the post-genomic age.
Xenotransplantation: Science, Ethics, and Public Policy
by Committee on Xenograft Transplantation: Ethical Issues Public PolicyXenotransplantation involves the transplantation of cells, tissues, and whole organs from one species to another. Interest in animal-to-human xenotransplants has been spurred by the continuing shortage of donated human organs and by advances in knowledge concerning the biology of organ and tissue rejection. The scientific advances and promise, however, raise complex questions that must be addressed.This book considers the scientific and medical feasibility of xenotransplantation and explores the ethical and public policy issues surrounding the possibility of renewed clinical trials. The volume focuses on the science base of xenotransplantation, public health risks of infectious disease transmission, and ethical and public policy issues, including the views of patients and their families.
Xenotransplantation: Ethical, Regulatory, and Social Aspects
by Daniel J. Hurst Luz Padilla Wayne D. ParisThis is the first volume to comprehensively discuss the ethical, regulatory, and social aspects of xenotransplantation research.Organized into four parts, Xenotransplantation begins by examining ethical issues around informed consent of the potential xenograft recipient, the major ethical issues encountered when doing this research on pigs, and allocation issues. Part two examines regulatory aspects from a global perspective, specifically from three major regions of the world doing xenotransplantation research currently, of which include the United States, Western Europe, and Asia. Following this, part three describes religious aspects of xenotransplantation amongst the major world religions, including Christianity, Islam, Judaism, and Hinduism. The book closes with an analysis of quantitative and qualitative studies conducted by the editors that assess the public’s perception of xenotransplantation. Featuring original data collected by the editors, this book is an instrumental resource for all clinicians involved in the research and practice of xenotransplantation.
Xenotransplantation and Risk: Regulating a Developing Biotechnology
by Sara FovargueSome developing biotechnologies challenge accepted legal and ethical norms because of the risks they pose. Xenotransplantation (cross-species transplantation) may prolong life but may also harm the xeno-recipient and the public due to its potential to transmit infectious diseases. These trans-boundary diseases emphasise the global nature of advances in health care and highlight the difficulties of identifying, monitoring and regulating such risks and thereby protecting individual and public health. Xenotransplantation raises questions about how uncertainty and risk are understood and accepted, and exposes tensions between private benefit and public health. Where public health is at risk, a precautionary approach informed by the harm principle supports prioritising the latter, but the issues raised by genetically engineered solid organ xenotransplants have not, as yet, been sufficiently discussed. This must occur prior to their clinical introduction because of the necessary changes to accepted norms which are needed to appropriately safeguard individual and public health.
Xerostomia: An Interdisciplinary Approach to Managing Dry Mouth
by Sarah GinsbergAn interdisciplinary textbook on dry mouth, Xerostomia: An Interdisciplinary Approach to Managing Dry Mouth provides an overview of xerostomia for physicians, dentists, nurses, speech-language pathologists, and otolaryngologists who encounter the condition in their practice. Xerostomia is a common condition, yet only one in seven cases are referred to a speech-language pathologist or otolaryngologist for treatment. Featuring contributions from speech-language pathologists, otolaryngologists, dentists, oral pathologists, and nurses, the text’s interdisciplinary approach and evidence-based framework provides practitioners with an awareness and understanding of xerostomia that will improve interprofessional coordination and enhance patient care. With a robust accompanying website including patient education resources, Xerostomia addresses the following topics: An otolaryngologist’s view of xerostomia, including causes, symptoms, evaluation, and treatment Patient perspectives of living with xerostomia, including quality of life measures and new research findings Effect of xerostomia on dental and oral health Voice disorders associated with xerostomia Impact of xerostomia on swallowing The science of saliva, including composition and production Pharmacological management of xerostomia Xerostomia: An Interdisciplinary Approach to Managing Dry Mouth provides indispensable information for general practitioners, internists, dentists, nurses, otolaryngologists, speech-language pathologists, and speech-language pathology students, as well as any health care practitioners who encounter patients with xerostomia.
Xie's Chinese Veterinary Herbology
by Huisheng Xie Vanessa PreastXie's Chinese Veterinary Herbology serves as a practical guide to the theory and application of Chinese Herbal Medicine into veterinary practices. Divided into three parts, the book covers herbal materia medica used in treating various disorders and diseases, herbal formulas, and the clinical application of treatments. The book also outlines each herb's history, the formulation of herbal recipes, energetic actions, indications and contraindications of each formula, dosages, and clinical and pharmacological studies performed with herbal treatments. This text serves as an invaluable reference to veterinarians looking to expand treatment options.
Xie's Veterinary Acupuncture
by Huisheng Xie Vanessa PreastTraditional Chinese Veterinary Medicine has been used to treat animals in China for thousands of years. Until now, the majority of the literature on Traditional Chinese Veterinary Medicine has been written in Chinese. Xie's Veterinary Acupuncture serves as a comprehensive and accessible reference on the basic principles, techniques and clinical application of veterinary acupuncture. Written by a world renowned authority on veterinary acupuncture and a panel of experts, the book incorporates a traditional Chinese approach to veterinary acupuncture, including ancient and newly developed acupuncture techniques for both small and large animals. With the growing interest in veterinary acupuncture worldwide, this ground-breaking and authoritative text is a timely resource for practitioners and students alike.
XIIIth International Symposium on Spermatology
by Lars Björndahl John Flanagan Rebecka Holmberg Ulrik KvistThese proceedings of the 2018 XIII International Symposium on Spermatology focus on comparative biology, and encourages discussion and the exchange of ideas. The aim of this Symposium was to provide a unique opportunity and bring together scientists from a wide spectrum of research fields – human, domestic animals and other mammals, vertebrates, insects, and plants. The underlying focus is on the function of the spermatozoon – a common feature for sexual reproduction, but extremely varied. By exploring the variability, a better understanding of male reproductive functions can develop. These proceedings address the mechanisms of physiology and pathophysiology, rather than diagnosis and treatment. The symposium featured keynote lectures by invited speakers, followed by presentations on specific aspects of the general topic of the session. Experimental studies are given priority over clinical studies of patient populations. The proceedings comprise both keynote speakers' texts and selected free communications. Posters were considered for publication in the proceedings, and the volume includes exhibited materials on the work of prominent spermatologists, highlighting their important past achievements in the field.
XLV Mexican Conference on Biomedical Engineering: Proceedings of CNIB 2022, 6–8 October, Puerto Vallarta, México (IFMBE Proceedings #86)
by Dora-Luz Flores Citlalli Jessica Trujillo-Romero Rafael Gonzalez-Landaeta Christian Chapa-González Guadalupe Dorantes-Méndez J. J. Agustin Flores Cuautle Martha R. Ortiz-Posadas Ricardo A. Salido Ruiz Esmeralda Zuñiga-AguilarThis book reports on fundamental research, cutting-edge technologies and industrially-relevant applications in biomedical engineering. It covers methods for analysis, modeling and simulation of biological systems, reporting on the development and design of advanced biosensors, nanoparticles and wearable devices. It covers applications in disease monitoring and therapy, tissue engineering, sport and rehabilitation, and telehealth. It also reports on engineering methods for improving and monitoring medical service, and on advanced robotic applications. Gathering the proceedings of the XLV Congreso Nacional de Ingeniería Biomédica (CNIB2022), organised by the Mexican Society of Biomedical Engineering, this book offers a timely snapshot on technologies and methods in bioengineering, and on challenges related to their practical implementation in the health sector.
XLVI Mexican Conference on Biomedical Engineering: Proceedings of CNIB 2023, November 2–4, 2023, Villahermosa Tabasco, México - Volume 1: Signal Processing And Bioinformatics (IFMBE Proceedings #96)
by José de Jesús Agustín Flores Cuautle Balam Benítez-Mata Ricardo Antonio Salido-Ruiz Gustavo Adolfo Alonso-Silverio Guadalupe Dorantes-Méndez Esmeralda Zúñiga-Aguilar Hugo A. Vélez-Pérez Edgar Del Hierro-Gutiérrez Aldo Rodrigo Mejía-RodríguezThis book reports on cutting-edge research and best practices in the broad fiel of biomedical engineering. Based on the XLVI Mexican Congress on Biomedical Engineering, CNIB 2023, held on November 2-4, 2023 in Villahermosa Tabasco, Mexico, this first volume of the proceedings covers research topics in biomedical signals and image processing, artificial intelligence, biosensors, and wearable systems, with applications ranging from disease classification and diagnosis, to health monitoring and medical therapy. All in all, this book provides a timely snapshot on state-of-the-art achievements in biomedical engineering and current challenges in the field. It addresses both researchers and professionals, and it is expect to foster future collaborations between the two groups, as well as international collaborations..
XLVI Mexican Conference on Biomedical Engineering: Proceedings of CNIB 2023, November 2–4, 2023, Villahermosa Tabasco, México - Volume 2: Biomechanics, Rehabilitation and Clinical Engineering (IFMBE Proceedings #97)
by José de Jesús Agustín Flores Cuautle Balam Benítez-Mata Ricardo Antonio Salido-Ruiz Gustavo Adolfo Alonso-Silverio Guadalupe Dorantes-Méndez Esmeralda Zúñiga-Aguilar Hugo A. Vélez-Pérez Edgar Del Hierro-Gutiérrez Aldo Rodrigo Mejía-RodríguezThis book reports on cutting-edge research and best practices in the broad fiel of biomedical engineering. Based on the XLVI Mexican Congress on Biomedical Engineering, CNIB 2023, held on November 2-4, 2023 in Villahermosa Tabasco, Mexico, this second volume of the proceedings covers research topics in biomechanics, materials and engineering design and manufacturing, with applications in prostheses design and development, tissue engineering, medical device assessment and healthcare management. All in all, this book provides a timely snapshot on state-of-the-art achievements in biomedical engineering and current challenges in the field. It addresses both researchers and professionals, and it is expect to foster future collaborations between the two groups, as well as international collaborations. .
The XX Brain: The Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer's Disease
by Lisa Mosconi"In The XX Brain, Lisa meticulously guides us in the ways we can both nourish and protect ourselves, body and mind, to ensure our brains remain resilient throughout our lives."--from the foreword by Maria ShriverThe first book to address cognitive enhancement and Alzheimer's prevention specifically in women--and to frame brain health as an essential component of Women's Health.In this revolutionary book, Dr. Lisa Mosconi, director of the Women's Brain Initiative at Weill Cornell Medical College, provides women with the first plan to address the unique risks of the female brain.Until now, medical research has focused on "bikini medicine," assuming that women are essentially men with breasts and tubes. Yet women are far more likely than men to suffer from anxiety, depression, migraines, brain injuries, and strokes. They are also twice as likely to end their lives suffering from Alzheimer's disease, even when their longer lifespans are taken into account. But in the past, the female brain has received astonishingly little attention and was rarely studied by medical researchers-- resulting in a wealth of misinformation about women's health.The XX Brain confronts this crisis by revealing how the two powerful X chromosomes that distinguish women from men impact the brain first and foremost and by focusing on a key brain-protective hormone: estrogen.Taking on all aspects of women's health, including brain fog, memory lapses, depression, stress, insomnia, hormonal imbalances, and the increased risk of dementia, Dr. Mosconi introduces cutting-edge, evidence-based approaches to protecting the female brain, including a specific diet proven to work for women, strategies to reduce stress, and useful tips for restorative sleep. She also examines the controversy about soy and hormonal replacement therapy, takes on the perils of environmental toxins, and examines the role of our microbiome. Perhaps best of all, she makes clear that it is never too late to take care of yourself.The XX Brain is a rallying cry for women to have full access to information regarding what is going on in their brains and bodies as well as a roadmap for the path to optimal, lifelong brain health.
XXVI Brazilian Congress on Biomedical Engineering: CBEB 2018, Armação de Buzios, RJ, Brazil, 21-25 October 2018 (Vol. 1) (IFMBE Proceedings #70/1)
by Rodrigo Costa-Felix João Carlos Machado André Victor AlvarengaThis volume presents the proceedings of the Brazilian Congress on Biomedical Engineering (CBEB 2018). The conference was organised by the Brazilian Society on Biomedical Engineering (SBEB) and held in Armação de Buzios, Rio de Janeiro, Brazil from 21-25 October, 2018. Topics of the proceedings include these 11 tracks: • Bioengineering • Biomaterials, Tissue Engineering and Artificial Organs • Biomechanics and Rehabilitation • Biomedical Devices and Instrumentation • Biomedical Robotics, Assistive Technologies and Health Informatics • Clinical Engineering and Health Technology Assessment • Metrology, Standardization, Testing and Quality in Health • Biomedical Signal and Image Processing • Neural Engineering • Special Topics • Systems and Technologies for Therapy and Diagnosis
XXVI Brazilian Congress on Biomedical Engineering: CBEB 2018, Armação de Buzios, RJ, Brazil, 21-25 October 2018 (Vol. 2) (IFMBE Proceedings #70/2)
by Rodrigo Costa-Felix João Carlos Machado André Victor AlvarengaThis volume presents the proceedings of the Brazilian Congress on Biomedical Engineering (CBEB 2018). The conference was organised by the Brazilian Society on Biomedical Engineering (SBEB) and held in Armação de Buzios, Rio de Janeiro, Brazil from 21-25 October, 2018.Topics of the proceedings include these 11 tracks:• Bioengineering• Biomaterials, Tissue Engineering and Artificial Organs• Biomechanics and Rehabilitation• Biomedical Devices and Instrumentation• Biomedical Robotics, Assistive Technologies and Health Informatics• Clinical Engineering and Health Technology Assessment• Metrology, Standardization, Testing and Quality in Health• Biomedical Signal and Image Processing• Neural Engineering• Special Topics• Systems and Technologies for Therapy and Diagnosis
YAC Protocols
by Alasdair MackenzieThis completely revised and updated edition of YAC Protocols takes advantage of the many new advances in biology since the publication of the first edition, including the sequencing of the human genome, the genomes of a wide variety of other organisms, and the increased use of transgenic animals for understanding the molecular basis of human and animal disease. This volume also provides a much-needed update on the new techniques currently employed and to help redefine and illustrate the important roles still to be played by yeast artificial chromosome (YAC) technologies in the postgenomic age. YAC Protocols, Second Edition, demonstrates the enormous potential use of YAC technologies in understanding the role of genetics in maintaining health, promoting pathogenesis, and conferring susceptibility to disease. Offering solutions to the many problems that have plagued researchers, this new edition allows for the wider and more efficient use of YAC technologies for the analysis of genetic and pathogenic causes of human disease.
YAC Protocols
by David MarkieIn YAC Protocols experienced researchers offer a comprehensive collection of their easily reproducible and proven methods for analyzing complex human, animal, and plant genomes. The step-by-step protocols cover all aspects of yeast artificial chromosomes, ranging from the construction of YAC libraries to their storage, screening, and database management, and to their use in such specialist applications as the transfer of YACs to mammalian cells and the isolation of coding sequences from YACs. YAC Protocols allows workers to add promising approaches adapted from yeast genetics to their personal repertoires and to introduce novel techniques emerging from the accumulating experience with YACs as a tool for genome analysis. Its extensive notes and background information not only significantly enhance the effective use of the methods, but also provide a valuable hands-on resource for those wishing to adapt protocols to suit their own applications.
Yaffe and Aranda's Neonatal and Pediatric Pharmacology: Therapeutic Principles in Practice
by Jacob V. ArandaThe premier comprehensive textbook in the field, Yaffe and Aranda’s Neonatal and Pediatric Pharmacology, Fifth Edition, provides an authoritative overview of all aspects of drug therapy in newborns, children, and adolescents. It offers evidence-based guidelines for safe, effective, and rational drug therapy, including specific recommendations for all major drug classes and diseases. Now in a vibrant two-color format, this fully revised reference is an indispensable resource for pediatricians, neonatologists, pediatric residents, and fellows in different pediatric subspecialties, including neonatal medicine and pediatric critical care.
The Yale Guide to Women's Reproductive Health: From Menarche to Menopause
by Mary Jane Minkin Carol V. WrightThis book is for every woman who has wished for an unhurried, personal conversation with a sympathetic doctor who will answer her questions about reproductive health. With warmth and understanding, the authors respond to questions about the gynecological issues that concern women today.