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Viral Hepatitis in Children: Prevention and Management
by Mei-Hwei Chang Kathleen B. SchwarzThis book is aimed to emphasize the rationale and importance of prevention and management of viral hepatitis in children, providing cutting edge knowledge. Viral hepatitis is a major health problem in the world. Although most complications of viral hepatitis are observed in adults, primary infection with hepatitis viruses often occurs during infancy or childhood. To better control viral hepatitis, prevention and therapy if possible should be started in childhood. This book offers updated and unique information about viral hepatitis in children, which has vitally important impact on global disease outcome and control, yet not discussed as frequently as viral hepatitis in adults in previous medical literature. Better prevention and management strategies are covered, starting from infancy and childhood, and even earlier during fetal life. It will be very helpful for better control of viral hepatitis both for daily practice and for developing future strategies and directions. If we can successfully control viral hepatitis in children, there will be very little remaining chronic hepatitis and related complications such as liver cirrhosis or hepatoma in adults. We hope readers, including medical students, researchers, pediatricians, family medicine physicians, infectious disease personnel, public health workers, gastroenterologists, hepatologists and parents of children with chronic hepatitis, will be benefited by reading this book.
Viral Hepatitis in Children
by Maureen M. JonasViral Hepatitis in Children: Unique Features and Opportunities is a unique volume that has been created to address the special considerations regarding viral hepatitis in children. It includes the latest information and recommendations specifically directed at the pediatric population, and highlights the knowledge gaps which will need to be filled to improve our understanding of these infections and treatment of this special group. Experienced practitioners from around the world have contributed these reviews, incorporating the latest studies, the current recommendations, and the distinctive pediatric issues that shape clinical care. This material will determine the research agenda for this field going forward. Viral Hepatitis in Children: Unique Features and Opportunities is a valuable resource for pediatricians, pediatric gastroenterologists, hepatologists and infectious disease specialists that care for children with viral hepatitis.
Viral Infections in Children, Volume I
by Robin J. GreenThe purpose of this book is to provide a synthesis of the ever evolving field of pediatric viral infections. The most common and exotic pediatric viral infections are fully reviewed in this first one of a two volume set. All contributions are written by recognized experts in the field. The publication will appeal to medical microbiologists, practitioners, medical students and other health care providers with a pediatric interest. The known literature on viral infections in children is summarized and discussed in the light of changes in thinking as a result of novel and new evidence.
Viral Infections in Children, Volume II
by Robin J. GreenThis second one of a two volume set will be of interest to medical microbiologists, practitioners, medical students and other health care providers who are engaged in management and treatment of pediatric viral infections. New evidence on topics related to better clinical management of patients is presented. The book may double as a clinical guide to care with algorithms, Practice Points and photographs and therefore aid the clinical decision making in management of sick children.
Viral Infections of the Human Nervous System
by Alan C. JacksonViral infections of the nervous system are important because they are associated with high morbidity and mortality. A variety of pathogenetic mechanisms are involved in these infections and an understanding of the pathogenesis is essential in understanding the diagnostic and clinical management aspects of the disease. Specialized investigations are often necessary for definitive diagnosis, although a presumptive diagnosis should often be suspected on the basis of the clinical features. Many of the chapters in this book are written by neurologists who are experts in basic science research of their topic in addition to active clinical practice in their specialty.
Viral Loads: Anthropologies of Urgency In the Time of Covid-19 (Embodying Inequalities: Perspectives from Medical Anthropology)
by Lenore Manderson Nancy J. Burke Ayo WahlbergDrawing upon the empirical scholarship and research expertise of contributors from all settled continents and from diverse life settings and economies, Viral Loads illustrates how the COVID-19 pandemic, and responses to it, lay bare and load onto people’s lived realities in countries around the world. A crosscutting theme pertains to how social unevenness and gross economic disparities are shaping global and local responses to the pandemic, and illustrate the effects of both the virus and efforts to contain it in ways that amplify these inequalities. At the same time, the contributions highlight the nature of contemporary social life, including virtual communication, the nature of communities, neoliberalism and contemporary political economies, and the shifting nature of nation states and the role of government. <p><p> Over half of the world’s population has been affected by restrictions of movement, with physical distancing requirements and self-isolation recommendations impacting profoundly on everyday life but also on the economy, resulting also, in turn, with dramatic shifts in the economy and in mass unemployment. By reflecting on how the pandemic has interrupted daily lives, state infrastructures and healthcare systems, the contributing authors in this volume mobilise anthropological theories and concepts to locate the pandemic in a highly connected and exceedingly unequal world. The book is ambitious in its scope – spanning the entire globe – and daring in its insistence that medical anthropology must be a part of the growing calls to build a new world.
Viral Metagenomics: Methods and Protocols (Methods in Molecular Biology #2732)
by Vitantonio Pantaleo Laura MiozziThis second edition volume expands on the previous edition with discussions about the latest viral metagenomics aspects covering a range of different specimens such as soil, freshwater, wastewater, fecal samples, blood plasma, clinical tissues, fungi, and herbarium samples. Chapters also look at different viral groups including archaeal viruses, eukaryotic viruses, phages, mycoviruses, and circular DNA viruses. Techniques required for studying the three viral metagenomic steps of samples processing, library construction, and analysis of data are also discussed. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Vital Metagenomics: Methods and Protocols, Second Edition is a valuable resource for researchers who are interested in learning more about this important and developing field.
Viral Molecular Machines
by Michael G. Rossmann Venigalla B. RaoThis book will contain a series of solicited chapters that concern with the molecular machines required by viruses to perform various essential functions of virus life cycle. The first three chapters (Introduction, Molecular Machines and Virus Architecture) introduce the reader to the best known molecular machines and to the structure of viruses. The remainder of the book will examine in detail various stages of the viral life cycle. Beginning with the viral entry into a host cell, the book takes the reader through replication of the genome, synthesis and assembly of viral structural components, genome packaging and maturation into an infectious virion. Each chapter will describe the components of the respective machine in molecular or atomic detail, genetic and biochemical analyses, and mechanism. Topics are carefully selected so that the reader is exposed to systems where there is a substantial infusion of new knowledge in recent years, which greatly elevated the fundamental mechanistic understanding of the respective molecular machine. The authors will be encouraged to simplify the detailed knowledge to basic concepts, include provocative new ideas, as well as design colorful graphics, thus making the cutting-edge information accessible to broad audience.
The Viral Network: A Pathography of the H1N1 Influenza Pandemic
by Theresa MacPhailIn The Viral Network, Theresa MacPhail examines our collective fascination with and fear of viruses through the lens of the 2009 H1N1 pandemic. In April 2009, a novel strain of H1N1 influenza virus resulting from a combination of bird, swine, and human flu viruses emerged in Veracruz, Mexico. The Director-General of the World Health Organization (WHO) announced an official end to the pandemic in August 2010. Experts agree that the global death toll reached 284,500. The public health response to the pandemic was complicated by the simultaneous economic crisis and by the public scrutiny of official response in an atmosphere of widespread connectivity. MacPhail follows the H1N1 influenza virus's trajectory through time and space in order to construct a three-dimensional picture of what happens when global public health comes down with a case of the flu. The Viral Network affords a rare look inside the U.S. Centers for Disease Control, as well as Hong Kong's virology labs and Centre for Health Protection, during a pandemic. MacPhail looks at the day-to-day practices of virologists and epidemiologists to ask questions about the production of scientific knowledge, the construction of expertise, disease narratives, and the different "cultures" of public health in the United States, Europe, Hong Kong, and China. The chapters of the book move from the micro to the macro, from Hong Kong to Atlanta, from the lab to the WHO, from the pandemic past in 1918 to the future. The various historical, scientific, and cultural narratives about flu recounted in this book show how biological genes and cultural memes become interwoven in the stories we tell during a pandemic. Ultimately, MacPhail argues that the institution of global public health is as viral as the viruses it tracks, studies, and helps to contain or eradicate. The "global" is itself viral in nature.
Viral Pandemics: From Smallpox to COVID-19 & Mpox
by Rae-Ellen Kavey Allison KaveyThis new edition of Viral Pandemics illuminates how the increasing emergence of novel viruses has combined with intensifying global interconnectedness to create an escalating spiral of viral disease. It includes an introduction to the key characteristics of viral pathogens that make them so dangerous followed by a comprehensive survey of epidemic viral disease from 1900 to the present.Now featuring new chapters on COVID-19 and mpox, the book uses an historical narrative to follow the path of each virus from its original detection to its emergence as an explosive pandemic. This allows readers to appreciate the biologic potential of the virus, the dynamics of epidemic disease spread, and the contemporaneous abilities of medicine and science to contend with the pathogen. In parallel, the book discusses those elements of connectedness that enable a localized disease outbreak to become a global pandemic, allowing readers to appreciate the increasingly critical role that human activity plays in global disease. In the last two chapters, the authors take a different approach. A Look Back critically evaluates the response to COVID-19 against the history of the emergence of public health in response to several other modern global pandemics and identifies some lessons we can still learn to improve our response to future pandemics. A Way Forward integrates the biologic and environmental factors that emerged as critical in the analysis of all the pandemics in the book and then uses this composite picture to propose ways to interrupt the escalating cycle of viral pandemic disease. Written in a straightforward and accessible style, this book is ideal reading for students of public health and its history, the history of medicine and medical anthropology, as well as general readers keen to understand how viral pandemics have shaped, and continue to shape, millions of lives.
Viral Pandemics: From Smallpox to COVID-19
by Rae-Ellen W. Kavey Allison B. KaveyWritten by a public health practitioner and a medical historian, Viral Pandemics explores the terrifying world of viruses as the cause of all acute pandemics since 1900, including the COVID-19 pandemic. The book illuminates the critical dual roles of viral biology and increasing global interconnectedness that have resulted in an escalating pandemic spiral. Viral Pandemics is the first book to focus exclusively on pandemics caused by viruses and the first to report the COVID-19 pandemic. In each chapter, the historiographic narrative follows the path of the virus from its original detection through its first appearance as the cause of disease, to its emergence as an explosive pandemic. Scientific information is presented in an accessible, straightforward style in compelling narratives that introduce the extraordinary universe of diverse, opportunistic viruses whose remarkable capacities make them formidable adversaries. The book makes it clear that global viral disease challenges are a persistent reality with the potential to cause catastrophic loss of life and major social and economic damage. A summary chapter draws together lessons learned and develops a proposed multidisciplinary global response. Viral Pandemics is the only book that provides a complete historical narrative focused on viral pandemics. This comprehensive survey is designed for students and scholars in biology, epidemiology, public health, global history and the history of medicine, as well as general readers interested in the science of pandemics.
Viral Sovereignty and the Political Economy of Pandemics: What Explains How Countries Deal with Outbreaks? (Europa International Perspectives)
by Sophal EarOver the past few decades a number of emerging infectious diseases (EIDs) have disrupted societies throughout the world, including HIV, Ebola, H5N1 (or ‘‘avian flu’’) and SARS, and of course the coronavirus disease (COVID-19) which spread worldwide to become a global pandemic. As well as EIDs, countries and regions also contend with endemic diseases, such as malaria. There are many factors that have contributed to the rise in, and spread of, EIDs and other diseases, including overpopulation, rapid urbanization, environmental degradation, and antibiotic resistance. Political and cultural responses to disease can greatly affect their spread. The global community needs to defend itself against disease threats: one weak link is enough to start a chain reaction that results in a global pandemic such as COVID-19. Some states take a nationalistic approach towards combating disease; however, international cooperation and meaningful ‘‘viral sovereignty’’—empowering countries to create effective health institutions and surveillance systems in order to contain disease—must be considered. This volume, with a focus on Southeast Asia, Africa and North America, considers the intersection between disease, politics, science, and culture in the global battle against pandemics, making use of case studies and interviews to examine the ways in which governments and regions handle outbreaks and pandemics.
The Viral Storm: The Dawn Of A New Pandemic Age
by Nathan WolfeIn The Viral Storm, award-winning biologist Nathan Wolfe tells the story of how viruses and human beings have evolved side by side through history; how deadly viruses like HIV, swine flu, and bird flu almost wiped us out in the past; and why modern life has made our species vulnerable to the threat of a global pandemic. Wolfe's research missions to the jungles of Africa and the rain forests of Borneo have earned him the nickname "the Indiana Jones of virus hunters," and here Wolfe takes readers along on his groundbreaking and often dangerous research trips—to reveal the surprising origins of the most deadly diseases and to explain the role that viruses have played in human evolution. In a world where each new outbreak seems worse than the one before, Wolfe points the way forward, as new technologies are brought to bear in the most remote areas of the world to neutralize these viruses and even harness their power for the good of humanity. His provocative vision of the future will change the way we think about viruses, and perhaps remove a potential threat to humanity's survival.
Viral Therapy of Human Cancers
by Joseph G. Sinkovics Joseph C. HorvathFeaturing contributions from nearly 30 leading authorities, this pioneering work gauges the potential for viruses to act as oncolytic and anti-tumor agents for the treatment of cancers in humans-detailing the cancer-combative properties exhibited by viruses in nature, genetically engineered viruses, and viral oncolysates as evidenced in basic and e
Viral Times: Reflections on the COVID-19 and HIV Pandemics (Sexuality, Culture and Health)
by Jaime García-Iglesias Maurice Nagington Peter AggletonThis book explores the relationship between COVID-19 and AIDS. It considers both how the earlier HIV pandemic informed our engagement with COVID-19, as well as the ways in which COVID-19 has changed how we remember and experience AIDS.Individual sections focus on sexual and intimate relationships, inequalities and injustice, the progressive biomedicalisation of the response (in the absence of a vaccine or effective treatment or cure), and professional, practitioner and community perspectives on the pandemics. The authors come from a wide variety of backgrounds – including public health, nursing, law and legal studies, political studies, and the humanities and social sciences. The book contains contributions by established writers such as Dennis Altman, Shalini Bharat, Tim Dean, Deborah Lupton, Shubhada Maitra, Pauline Oosterhoff and Michael Tan, as well as chapters by Chris Ashford and Gareth Longstaff, Bernard Kelly, Dean Murphy and Kiran Pienaar, and Theodore (ted) Kerr.This thought-provoking and timely volume includes case studies from Australia, Austria, Brazil, Canada, Germany, India, Indonesia, the Philippines, the UK, the USA and Vietnam. It has been written for students and scholars from a wide range of disciplinary backgrounds, including sociology, healthcare, public health, social work, anthropology, and gender and sexuality studies. The book will also be of interest to the general reader who wants a better understanding of the social and cultural dimensions of modern-day pandemics and the personal and community responses to which they give rise.
The Viral Underclass: The Human Toll When Inequality and Disease Collide
by Steven W. Thrasher"An irresistibly readable and humane exploration of the barbarities of class...readers are gifted that most precious of things in these muddled times: a clear lens through which to see the world."—Naomi Klein, New York Times bestselling author of This Changes Everything and The Shock DoctrineFrom preeminent LGBTQ scholar, social critic, and journalist Steven W. Thrasher comes a powerful and crucial exploration of one of the most pressing issues of our times: how viruses expose the fault lines of society. Having spent a ground-breaking career studying the racialization, policing, and criminalization of HIV, Dr. Thrasher has come to understand a deeper truth at the heart of our society: that there are vast inequalities in who is able to survive viruses and that the ways in which viruses spread, kill, and take their toll are much more dependent on social structures than they are on biology alone.Told through the heart-rending stories of friends, activists, and teachers navigating the novel coronavirus, HIV, and other viruses, Dr. Thrasher brings the reader with him as he delves into the viral underclass and lays bare its inner workings. In the tradition of Isabel Wilkerson’s Caste and Michelle Alexander’s The New Jim Crow, The Viral Underclass helps us understand the world more deeply by showing the fraught relationship between privilege and survival.
Viral Vector Approaches in Neurobiology and Brain Diseases
by Riccardo BrambillaAiming toward improvement in the safety, efficiency, and specificity of viral vectors for neurobiological research and clinical applications, Viral Vector Approaches in Neurobiology and Brain Diseases covers key aspects related to the use of viral vectors in neuroscience, with a major emphasis on basic mechanisms of synaptic plasticity, learning, and memory, as well as molecular neuropharmacology and experimental animal models of brain disorders. The volume begins by delving into features of the viral vectors currently available in neuroscience and their production methods, and it then continues onward to examples of successful applications of viral vector technology to psychiatric and memory research, current applications of viral vector technology in the context of neurological disorders, as well as various cutting-edge applications of viral vector technology to neuroscience, including optogenetics. Written for the Neuromethods series, the chapters of this book contain the kind of detailed description and implementation advice that promotes successful, repeatable results. Practical and up to date, Viral Vector Approaches in Neurobiology and Brain Diseases will be useful not only to neurobiologists wishing to routinely use viral vectors in the laboratory but also to experienced scientists needing detailed new protocols for a variety of experimental applications.
Viral Vectors for Gene Therapy
by Curtis A. MachidaResearchers from academia and biotechnology describe proven molecular methods for the construction, development, and use of virus vectors for gene transfer and gene therapy. Offering detailed step-by-step instructions to ensure successful results, these experts detail the use of herpes viruses, adenoviruses, adeno-associated viruses, simple and complex retroviruses, including lentiviruses, and other virus systems for vector development and gene transfer. Additional chapters demonstrate the use of virus vectors in the brain and central nervous system. Comprehensive and highly practical, Viral Vectors for Gene Therapy: Methods and Protocols provides not only researchers with the basic tools needed to design targeted gene delivery vectors, but also clinicians with an understanding of how to apply viral vectors to the treatment of genetic disorders.
Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Biology #1937)
by Fredric P. Manfredsson Matthew J. BenskeyThis volume discusses protocols, ranging from vector production to delivery methods, used to execute gene therapy applications. Chapters are divided into four parts, and cover topics such as design, construction, and application of transcription activation-like effectors; multi-modal production of adeno-associated virus; construction of oncolytic herpes simplex virus; AAV-mediated gene delivery to the mouse liver; and intrathecal delivery of gene therapeutics by direct lumbar puncture in mice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and authoritative, Viral Vectors for Gene Therapy: Methods and Protocols is a valuable resource for researchers, clinicians, and students looking to utilize viral vectors in gene therapy experiments.
Viral Vectors for Gene Therapy
by Otto-Wilhelm Merten Mohamed Al-RubeaiThe huge potential for gene therapy to cure a wide range of diseases has led to high expectations and a great increase in research efforts in this area, particularly in the study of delivery via viral vectors, widely considered to be more efficient than DNA transfection. In Viral Vectors for Gene Therapy: Methods and Protocols, experts in the field present a collection of their knowledge and experience featuring methodologies that involve virus production, transferring protocols, and evaluating the efficacy of gene products. While thoroughly covering the most popular viral vector systems of adenovirus, retrovirus, and adeno-associated virus, this detailed volume also explores less common viral vector systems such as baculovirus, herpes virus, and measles virus, the growing interest in which is creating a considerable demand for large scale manufacturing and purification procedures. Written in the highly successful Methods in Molecular BiologyTM series format, many chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and vital tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Viral Vectors for Gene Therapy: Methods and Protocols provides basic principles accessible to scientists from a wide variety of backgrounds for the development of gene therapy viral products that are safe and effective.
Viral Vectors in Veterinary Vaccine Development: A Textbook
by Thiru Vanniasinkam Suresh K. Tikoo Siba K. SamalThis highly accessible textbook introduces readers to the development of viral vectors and discusses their application in veterinary vaccinology. It offers comprehensive information on the latest advances in this emerging research field, together with a broad overview of the history of veterinary vaccines and viral vectors. The book also addresses issues concerning funding, translational research and ethics that will impact the future development, manufacture and global use of viral vector-based veterinary vaccines. The book addresses the needs of graduate students and researchers in the fields of Veterinary Medicine, Virology and Immunology.
Viral World: Global Relations During the COVID-19 Pandemic (The COVID-19 Pandemic Series)
by Long T. BuiThis book argues that the catastrophe of COVID-19 provided a momentous time for groups, institutions, and states to reassess their worldviews and relationship to the entire world. Following multiple case studies across dozens of countries throughout the course of the pandemic, this book is a timely contribution to cultural knowledge about the pandemic and the viral politics at the heart of it. Mapping the various forms of global consciousness and connectivity engendered by the crisis, the book offers the framework of "viral worlding," defined as viral forms of relationality, becoming, and communication. It demonstrates how worlding or world-making processes accelerated with the novel coronavirus. New emergent forms of being global "went viral" to address conditions of inequality as well as forge possibilities for societal transformation. Considering the tumult wrought by the pandemic, Bui analyzes progressive movements for democracy, abolition, feminism, environmentalism, and socialism against the world-shattering forces of capitalism, authoritarianism, racism, and militarism. Focusing on ways the pandemic disproportionately impacted marginalized communities, particularly in the Global South, this book juxtaposes the closing of their lifeworlds and social worlds by hegemonic global actors with increased collective demands for freedom, mobility, and justice by vulnerable people. The breadth and depth of the book thus provides students, scholars, and general readers with critical insights to understanding the world(s) of COVID-19 and collective efforts to build better new ones.
Viren in allen Dimensionen: Wie ein Informationscode Viren, Software und Mikroorganismen steuert
by Rafael BallMikroorganismen, Viren und Computerprogramme codieren alle Informationen, die erforderlich sind, sich selbst zu vermehren und verbreiten. Dabei sind sich diese Mechanismen in der belebten Welt, in der Welt der Viren und sogar in der Welt der technischen Systeme verblüffend ähnlich. Das Buch zeigt auf, wie groß die Parallelen dieser verschiedenen belebten und unbelebten replizierenden Systeme sind und worauf sie basieren. Der Ausflug führt ebenso in die faszinierende Welt der Genetik, zur Frage, was Leben definiert und in die Programmierung von Software, die sich selbständig vervielfacht. Schließlich wird daraus die Frage abgeleitet, ob und inwieweit solche sich selbst replizierenden technischen Systeme genauso gefährlich werden können wie infektiöse Viren bei der Auslösung von Pandemien, wie etwa der Corona-Pandemie im Jahr 2020.
The Virgin Cure: A Novel
by Ami McKayFollowing in the footsteps of The Birth House, her powerful debut novel, The Virgin Cure secures Ami McKay's place as one of our most beguiling storytellers. (Not that it has to… that is pretty much taken care of!)"I am Moth, a girl from the lowest part of Chrystie Street, born to a slum-house mystic and the man who broke her heart." So begins The Virgin Cure, a novel set in the tenements of lower Manhattan in the year 1871. As a young child, Moth's father smiled, tipped his hat and walked away from his wife and daughter forever, and Moth has never stopped imagining that one day they may be reunited – despite knowing in her heart what he chose over them. Her hard mother is barely making a living with her fortune-telling, sometimes for well-heeled clients, yet Moth is all too aware of how she really pays the rent.Life would be so much better, Moth knows, if fortune had gone the other way - if only she'd had the luxury of a good family and some station in life. The young Moth spends her days wandering the streets of her own and better neighbourhoods, imagining what days are like for the wealthy women whose grand yet forbidding gardens she slips through when no one's looking. Yet every night Moth must return to the disease- and grief-ridden tenements she calls home.The summer Moth turns twelve, her mother puts a halt to her explorations by selling her boots to a local vendor, convinced that Moth was planning to run away. Wanting to make the most of her every asset, she also sells Moth to a wealthy woman as a servant, with no intention of ever seeing her again.These betrayals lead Moth to the wild, murky world of the Bowery, filled with house-thieves, pickpockets, beggars, sideshow freaks and prostitutes, but also a locale frequented by New York's social elite. Their patronage supports the shadowy undersphere, where businesses can flourish if they truly understand the importance of wealth and social standing - and of keeping secrets. In that world Moth meets Miss Everett, the owner of a brothel simply known as an "infant school." There Moth finds the orderly solace she has always wanted, and begins to imagine herself embarking upon a new path.Yet salvation does not come without its price: Miss Everett caters to gentlemen who pay dearly for companions who are "willing and clean," and the most desirable of them all are young virgins like Moth. That's not the worst of the situation, though. In a time and place where mysterious illnesses ravage those who haven't been cautious, no matter their social station, diseased men yearn for a "virgin cure" - thinking that deflowering a "fresh maid" can heal the incurable and tainted. Through the friendship of Dr. Sadie, a female physician who works to help young women like her, Moth learns to question and observe the world around her. Moth's new friends are falling prey to fates both expected and forced upon them, yet she knows the law will not protect her, and that polite society ignores her. Still she dreams of answering to no one but herself. There's a high price for such independence, though, and no one knows that better than a girl from Chrystie Street.
Virgin Midwife, Playboy Doctor
by Margaret McdonaghPenhallys most eligible bachelor finds a wife! Oliver Fawkner is new to Penhally Bay. This seriously sexy doctor, with a playboy reputation, has caused quite a stir with the female population! But Oliver is only interested in getting to know beautiful midwife Chloe MacKinnon Chloe loves her job, and dotes on her tiny patients. She has always put work before her social life, hiding from a traumatic past that has left her very inexperienced with men. But this gorgeous new doctor has won her trust and awakened something inside her Chloe knows that Oliver is only passing through Penhally dare she risk her heart with this playboy doctor? BRIDES OF PENHALLY BAY Bachelor doctors become husbands and fathers in a place where hearts are made whole.