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Thromboembolism in Orthopedic Surgery
by Juan LlauThis book reviews the main topics in thromboprophylaxis around orthopedic surgery, from a general scope of the problems with the disease highlighting them in orthopedics to the new specific protocols involving, for example, new oral anticoagulants. The prevalence of the venous thromboembolism in each procedure (from "easy" to "hard" surgeries, with different rates of related thrombosis) and the risk factors to bear in mind in each one (related and non-related with the orthopedic procedure) are also revised. A chapter focus on the diagnosis and treatment of venous thromboembolism, which is commonly "forgotten" in many books addressed to orthopedic surgeons and anaesthesiologists. The methods for thromboprophylaxis have three specific chapters: the most common drugs used and recommended when pharmacological prophylaxis is needed, new drugs which are arising day by day and which management will be of main importance in a close near future, and mechanical methods, recommended both as additional when possible and for sole indications when the risk of bleeding could move us to minimize the real risk of thrombosis. Anaesthetic implications for thromboprophylaxis and, also, main implications of the application of antithrombotic protocols in the anaesthetic practice are covered by another chapter. In our opinion it was very important to divide the orthopedic procedures according to their own thrombotic risk, so having their own protocols for thromboprophylaxis: high risk, day surgery procedures and "special" surgical procedures are included in three different chapters, from three different authors with complementary views. Finally, in a last chapter, we review the problems involving the perioperatory management of antiaggregated and anticoagulated patients, with a special part in hip fracture surgery.
Thrombolysis in Pulmonary Embolism
by Carlos Jerjes-SánchezThis book provides an up-to-date review of the use of thrombolytic therapy in the treatment of acute pulmonary embolism. It discusses the mechanisms of thrombosis; pharmacokinetics and pharmacodynamics of the most commonly used fibrinolytics; evidence-based results from multicenter control trials in which thrombolytic treatment was administered; criteria by which pulmonary embolism patients requiring thrombolysis are identified; and the use of thrombolytic therapy in special situations such as in in-transit thrombus and pregnancy. Focusing on peripheral intravenous thrombolysis, which can performed safely and effectively in emergency departments, hospital wards, and intensive critical care units in tertiary and community hospitals, Thrombolysis in Pulmonary Embolism is a valuable resource for cardiologists, pulmonologists, and internists.
Thrombolytic Therapy for Acute Stroke
by Patrick D. LydenThrombolytic therapy is finally starting to reach patients in a variety of settings all over the world. Formerly in the domain of sub-specialists, thrombolytic therapy now rests in the realm of Emergency Medicine, Intensive Care, Vascular, and Neuro hospital Medicine physicians. Increasingly, non-neurologists use thrombolytic therapy This is a significant advancement since the 2nd edition to Thrombolytic Therapy for Acute Stroke published, creating a significant need for a 3rd edition. Thrombolytic Therapy for Acute Stroke, 3rd edition will be a practical and thorough reference to all those caring for acute stroke patients Extensively updated from previous editions, new data and cases will provide guidance to this most effective stroke treatment. This text will be of great interest to physicians, residents and advanced practice nurses who treat acute stroke patients.
Thrombosis and Cancer
by Gilles Lugassy Anna Falanga Ajay K Kakkar BSc PhD FRCS Frederick R RicklesIt is common knowledge that thromboembolic disease is often the earliest manifestation and almost the most frequent complication of cancer. Recent studies have investigated the mechanisms by which cancer causes thrombosis and have emphasized the importance of the coagulation system in angiogenesis and tumor metastasis. Thrombosis and Cancer offers
Thrombosis and Embolism: from Research to Clinical Practice
by Md. Shahidul IslamThis unique publication explores diverse themes relating to thrombosis and embolism, from basic research at cell and molecular level to the actual care, prevention, and treatment of diverse categories of patients suffering from such diseases. Chapters cover a variety of topics including thrombosis and embolism in surgical patients, cancer patients, pregnant women and children and adolescents, as well as treatment of the conditions by traditional anticoagulants, novel oral anticoagulants, thrombolytic therapy, endovascular treatment and embolectomy. Readers may explore cutting edge research, recommendations from major societies, contemporary guidelines, areas of controversy and directions for ongoing and future research. The book features comprehensive information ranging from molecular mechanisms of diseases to the clinical features, diagnosis, and therapeutic regimens for treating a variety of clinical conditions. It has a broad appeal to scientists and research students as well as busy clinicians engaged in patient care, who will all find something important and useful amongst these carefully selected chapters.
Thrombosis and Hemostasis in Cancer (Cancer Treatment and Research #179)
by Gerald SoffIn this book, leaders in the field explore our current understanding of thrombosis and hemostasis in cancer and address key questions on the subject. Among the topics discussed are the mechanisms that cancers use to activate the coagulation system, and those by means of which an activated coagulation system can lead to more aggressive cancer growth. Clinical chapters examine the role of thrombosis prophylaxis and treatment, central line-associated thrombosis, and cancer-associated hemorrhage. Subsequent chapters deal with the management of chemotherapy-induced thrombocytopenia, anticoagulation in the presence of brain metastases, and other unique challenges in the interaction of thrombosis and hemostasis in cancer. It has been 150 years since Armand Trousseau first described the well-known association between cancer and an increased risk of thrombosis, which may be considered the first paraneoplastic syndrome ever identified. More recently, numerous studies have indicated that activation of the coagulation system by cancer not only increases the likelihood of thrombosis, but is also associated with a more aggressive cancer phenotype. By familiarizing readers with the latest developments in this complex and challenging field, the book offers a valuable resource for scientists and clinicians alike.
Thrombosis and Thromboembolism
by Samuel Z. Goldhaber Paul M. RidkerWritten and edited by world-renowned leaders in the field!Presents new directions for the prevention and treatment of arterial and venous cardiovascular thrombotic and thromboembolic diseases.Updates contemporary thinking regarding low-molecular-weight-heparins (LMWH), platelet receptor antagonists, and direct thrombin inhibitors to
Thrombus and Stroke
by Ajay K. Wakhloo Matthew J. Gounis Baruch B. Lieber Robert A. Mericle Italo LinfanteProviding a clear foundation as to what a clot is, how it forms, and the most recent approaches to treatment, Thrombus and Stroke is an all-inclusive resource covering:The fundamental science of clot formation and the pharmacokinetics of thrombolysis The clinical impact of thrombus as it pertains to stroke and the most recent clinical and minimally
Through The Kaleidoscope: Viewing The Contributions Of The Behavioral And Social Sciences To Health
by National Research Council Staff Institute of Medicine Staff Lisa F. Berkman Summary of the Institute of Medicine Symposium on Contributions of the Behavioral Social Sciences to Health StaffA report on Viewing The Contributions Of The Behavioral And Social Sciences To Health
Through My Eyes: The Story of a Surgeon Who Took On the Medical World
by Charles D. Kelman"This book may ruffle feathers and bruise egos, but its fascinating tale adds a human quality to medical research." Dr. Frank Field Through My Eyes reads like a true adventure story. From the day his high school principal told him he wasn't college material and ought to go to trade school, Charles Kelman has upset conventional wisdom - with stunning success. As a pioneering ophthalmologist, Dr. Kelman bucked the whole medical establishment in his search for a less risky, less intrusive, and more effective method of cataract removal. Today, thanks to his persistence and smarts, thousands of people can see again. The "Rocky" of medicine, Dr. Kelman recounts his early struggles to achieve a breakthrough in surgical procedure-a battle Dr. Kelman had to wage in the face of intense skepticism from his colleagues. Through My Eyes tells the stories of the many famous people whose sight Dr. Kelman ultimately managed to save, including actress Hedy Lamarr, Senator Bob Packwood, jazz musician Lionel Hampton, singer Jan Peerce, and hundreds of others. But Charles Kelman also has a burgeoning second career- as a singer, saxophonist, and comedian. To his friends and fans he's known as "Dr. Jazz." And when he's not performing cataract surgery, he's performing at Carnegie Hall in New York, Caesar's Palace in Las Vegas, the Atlantis in Atlantic City, or on the "Tonight Show" with Johnny Carson. He has appeared on the stage with such performers as Glen Campbell, the Spinners, and Lionel Hampton. Through My Eyes shows how single-minded persistence and determination pay off. While this autobiography is bound to stir controversy in the medical world, Dr. Charles Kelman's story combines scientific savvy with personal style-showing how one adventurous man, all by himself, can make good, and make a difference. Charles D. Kelman, M.D., is a practicing ophthalmologist in New York City and the author of Cataracts: What You Must Know About Them. He is a clinical professor of Ophthalmology at New York Medical College. In addition to his regular medical duties, he is currently conducting research into macular degeneration of the retina, and-in his show business career-he is writing a musical for Broadway. Dr. Kelman lives in New York City.
Through My Eyes: My Four Week Experience in Post-earthquake Haiti
by Debbie SalernoImagine that in eight short minutes your entire world comes crashing down upon you, literally. What would you do if you lost your home, your livelihood, your family, and your entire support network?
Through the Glass Wall: A Therapist's Lifelong Journey to Reach the Children of Autism
by Howard ButenA remarkable testament of hope and love, these pages recount Howard Buten's lifelong journey working with autistic children. For three decades his pioneering, often controversial approaches have enabled him to gain access to their strange and solitary universe--a universe he shares in a book that is unlike any you've ever read. From his first unforgettable encounter with a wild, clawing human hurricane in the form of a little boy named Adam S., clinical psychologist Howard Buten has sought ways into the seemingly closed world of the autistic child. Whether he's done this by letting himself be pummeled, scratched, and bitten, or by imitating the child's behaviors, or by feeling himself into what the child must be feeling, he has often been rewarded. With extraordinary insight and in ways that are powerfully moving, he brings to life as never before the innermost selves of these children.Among those you'll meet in the clinic he founded in Paris are Lise, whose seemingly random movements are as expressive as a dancer's; Florian, who can instantly tell you on which day of the week your birthday falls for any year, past or future; Martin, whose nonstop speech echoes the angry voices he has heard all around him, but who is impervious to the emotions they contain; and Hakim, a child so lost and so violent, no other institution will take him.Writing with a scientist's clarity and a humanist's heart, Buten conveys the reality of autism with passion, ruthlessness, humor, wisdom--and love. This is a book both heartbreaking and hopeful, and when he succeeds in breaching the invisible wall of aloneness that seems to separate the autistic from the rest of us, we cheer.From the Hardcover edition.
Through the Seasons: Activities for Memory-Challenged Adults and Their Caregivers (A Johns Hopkins Press Health Book)
by Cynthia R. Green Joan BeloffA collection of easy-to-follow activities, organized by seasons of the year, to help family members and caregivers engage with memory-challenged adults.Dementia and related disorders impact the lives of those affected in countless ways, making it difficult to remain independent at work, at home, and in the wider world. But recent studies have shown that structured activities can make a significant, positive difference by stimulating mental engagement while improving interactions between caregivers and memory-challenged adults.Fun and easy to use, this large-format, full-color picture book is divided into themes representing the four seasons. Each section describes several multisensory experiences—such as walking on the beach, making ice cream, or planting flowers—along with related topics for discussion and activities to elicit memories and encourage new positive associations. The topics and activities incorporate all five senses to facilitate connections and conversations.The book adopts a compassionate, person-centered approach and is designed so that two people can easily look together while sitting side by side. This latest edition, which has been thoroughly revised, • takes a multicultural approach• includes all-new images, as well as 14 completely new highlighted activities • integrates modern wellness concepts• features a new introduction and an updated resource section• offers guidance about activity planning and optimizing interactions between care partners and the individual with dementiaHelping you and your loved one make cherished new memories, Through the Seasons is an indispensable solution to the question of what to do together to maintain well-being and connection.
Through A Vet’s Eyes: How we can all choose a better life for animals
by Dr Sean Wensley FRCVSOne of the Financial Times' Best Summer Books of 2022 A vet's eye-opening polemic about our relationship with animals; how we treat them, what it feels like from their perspective, how we get it wrong and what we can do to fix it.Dr Sean Wensley is an award-winning vet and lifelong naturalist who has contributed to animal welfare and conservation projects all over the world. His debut book is about how we can choose a better life for animals, from the chickens we eat to the pets we keep.As our societies become more urbanised, we are further removed from the reality of where and how our food is produced. Reported surveys have suggested that 1 in 4 UK adults don't know that bacon comes from pigs. On the opposite end of the spectrum, the humanisation of our pets is a risk to their welfare; with over 60% of UK dogs being overweight or obese, we are effectively killing them with kindness. Through A Vet's Eyes seeks to redress this imbalance so that we see all animals as thinking, feeling beings not dissimilar to ourselves. As he takes us through the years in which he trained to become a vet, and set against a backdrop of inspiring natural spectacles, Dr Wensley shares his first-hand experience of how animals are treated and used for our benefit. He interrogates the different levels of welfare afforded to them and reveals how we the general consumer can reduce our animal welfare footprint through the choices we make every day.(P) Octopus Publishing Group 2022
Throwaway Players
by Gay CulverhouseThe NFL insists players know they're playing a dangerous game, but players never see the deteriorated mental capacities of their former heroes. Throwaway Players is former Tampa Bay Buccaneers president Gay Culverhouse's story of the broken bodies and lost souls of the men who have left the locker room and what remains after the cheering subsides. Focused on making money rather than the well-being of their players, this is the dark side of football the NFL doesn't want fans to see.Additionally, high schools, colleges, and independent sports organizations have little oversight when choosing player's equipment. This breeds a new generation of kids suffering from multiple concussions and damaged lives. Throwaway Players offers guidance to parents navigating the world of competitive sports as well as advocacy and resources for athletes often left in the dark about appropriate procedures for treating injuries, especially head traumas. Throwaway Players is essential reading for any parent, athlete, and sports fan.Gay Culverhouse testified before Congress on football head injuries and successfully changed the policy of including an independent neurologist on the sidelines of every NFL game. Gay's work with former players has appeared in The New York Times, Sarasota Herald Tribune, St. Petersburg Times, The Tampa Tribune, Time magazine, and many more. She has appeared on several radio shows, including PBS and ESPN, and is featured in three documentaries that are in post-production (with CNN, ESPN, and an independent filmmaker). In November 2009 Gay formed The Gay Culverhouse Players' Outreach Program, Inc., a nonprofit organization to further the work nationally for retired players.
Thuisloosheid bij jongeren en volwassenen (Werken in SPH)
by M. Magnee Marijke van Bommel M.J. van Deutekom B. Fontaine A.J. RavelliDit cahier gaat over jonge en volwassen thuislozen. De auteurs bespreken wie deze thuislozen zijn en hoe ze in die situatie zijn terechtgekomen. In de afgelopen decennia zijn allerlei voorzieningen voor thuislozen geïnitieerd. De huidige trend is om het gefragmentariseerde aanbod meer op elkaar af te stemmen en organisatorisch onder één noemer te brengen. Tegelijkertijd zijn er veranderingen aan de gang in de methodieken voor jongeren en volwassenen. Deze veranderingen zijn onder meer terug te vinden in de opleidingen voor hulpverleners en in de professionalisering van de zorg. Dit cahier biedt een beknopt overzicht van de stand van zaken.
Thymic Development and Selection of T Lymphocytes
by Thomas Boehm Yousuke TakahamaThe thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.
The Thymus in Health and Senescence: Volume 2 Aging and Endocrinology (Routledge Revivals #2)
by Nathan F. CardarelliFirst published in 1989: This text was written to provide a relatively broad comprehensive study of the thymus in health and disease, including relationships to the endocrine system, immue system, and again.
Thymus Transcriptome and Cell Biology (Advances in Experimental Medicine and Biology #1471)
by Geraldo A. Passos Daniella Arêas Mendes-da-Cruz Wilson SavinoThis volume focuses on a challenging field in biomedicine: the genetic control of central immune tolerance. The thymus gland is a lymphoid organ implicated in T cells' maturation, differentiation, and selection. Its function is associated with the control of immune homeostasis in the body, establishing central immune tolerance, and preventing the onset of autoimmune diseases. This book focuses on thymus development, their cellular components and their respective function, and the peculiar gene expression profiling (transcriptome) found in the medullary thymic epithelial cells (mTECs) that are implicated in the self-representation in the thymus and the Autoimmune regulator (Aire) gene. Chapters also explore the mutations in the Aire gene, manifestation of autoimmune diseases, and the role of cell-cell interactions within the thymus with implications in the negative selection (elimination) of nascent autoreactive T cells in preventing aggressive autoimmunity. This new edition includes two new chapters devoted to the genome editing of the Aire gene through Crispr-Cas9 system, and thymic involution.All chapters have been updated to reflect the latest research in the field.
Thyroid: How to prevent, take care of oneself, and stay healthy
by Daniela PaceThis book is a journey around the vast subject of the thyroid, designed to share information about its functioning and the pathologies that can affect it. It is intended to provide accessible and simplified language, distancing itself from technicalities of the medical profession.It represents an itinerary that invites step-by-step learning and taking care of one's own health through prevention and the adoption of healthy lifestyle habits. Reading it helps improve visual memory and facilitates the acquisition of concepts, shortening the distances for both the reader and the specialist. The medical-scientific information maintained in this book maintains its authoritative nature while promoting sharing.This book is for everyone: young, adults, and the elderly. It is for you, for your well-being and the well-being of your loved ones.
Thyroid and Heart: A Comprehensive Translational Essay
by Alessandro Pingitore Giorgio Iervasi A. Martin Gerdes Salman RazviIn recent years, several scientific papers have highlighted the role of the thyroid system in cardioprotection, and several clinical studies – including multicenter studies – have identified the role of thyroid hormones (TH) in the development and progression of cardiovascular disease, making an update of TH and heart relationship both necessary and timely. This second edition of Thyroid and Heart failure provides a careful and updated review of the experimental, clinical and epidemiological results in the field of TH and heart failure, with a particular focus on the translational - bench to bedside - significance of the obtained results. It discusses topics such as the molecular, structural, functional, cellular and histological cardiac changes; the reversibility of these changes with TH replacement therapy; the systemic effects – kidney, hormonal pathways systems, brain, muscle, etc – of altered TH metabolism in HF, as well as the clinical and prognostic implications. The section devoted to the potential therapeutic treatments has been expanded. Thanks to its translational approach to this highly complex subject, the book will be of interest to a broad readership, including cardiologists, endocrinologists and internists.
The Thyroid and Its Diseases: A Comprehensive Guide For The Clinician
by Markus Luster Leonidas H. Duntas Leonard WartofskyThis book is an up-to-date and comprehensive guide to all the common thyroid disorders that may be seen by internists, endocrinologists, nuclear medicine physicians, and endocrine surgeons. While the fundamentals of thyroid hormone function and regulation in health and disease are well covered, the primary focus is on the clinical approach to thyroid disease, with detailed coverage of both initial diagnosis and management and the role of imaging. Because most endocrine diseases are chronic and lifelong, special emphasis is placed on long-term management and the common pitfalls that may be encountered by the clinician. The editors are internationally acknowledged leaders in the field of thyroid disease and have gathered an outstanding team of authors, all of whom are also highly expert in their respective areas, but who, equally importantly, write in a clear and lucid style. The numerous isotope scan and ultrasonographic images ensure that the book will serve as a valuable reference atlas to which the physician will return again and again.
Thyroid and Parathyroid Diseases: A Case-Based Guide
by Tamer Özülker Mine Adaş Semra GünayThis book presents as teaching files a collection of cases of thyroid and parathyroid diseases seen at various high-volume endocrinology centers. The cases, most of which are accompanied by instructive images, have been selected in order to impart clinically relevant knowledge on the full range of endocrine disorders of thyroid and parathyroid origin. Accordingly, the book covers not only situations that are frequently encountered by the clinician in primary care, but also uncommon disorders and unusual presentations of common disorders. The comprehensive nature of the coverage will assist in resolving diagnostic dilemmas, and the reader will also find up-to-date information on disease management. The recommendations provided are based on current evidence-based clinical practice guidelines and are supported by relevant literature so as to harmonize available evidence-based protocols with current clinical practice. Thyroid and Parathyroid Diseases: A Case-Based Guide is designed to be thought provoking and to aid knowledge retention. Written by renowned experts in nuclear medicine, clinical endocrinology, oncology, and general surgery, it will appeal to specialists and residents in these fields.
Thyroid and Parathyroid Disorders in Children: A Practical Handbook
by Pallavi Iyer and Herbert ChenThyroid and Parathyroid Disorders in Children: A Practical Handbook offers a focused and practical approach to diagnostic and therapeutic (both medical and surgical) interventions in management of thyroid and parathyroid diseases in children. It is divided into two sections: thyroid and parathyroid, with each section discussing the use of the laboratory testing and radiographic modalities in the study of these glands. This guides the reader to know the utility and limitations of the findings when approaching a child with these conditions. Written by international experts in the fields of pediatric endocrinology and endocrine surgery, it is ideal for trainees, practicing physicians and professionals who care for children with endocrine conditions. Key Features Discusses differences in recognition and management of thyroid and parathyroid disorders in children compared with adults, with both common and rare disorders described along with their medical and surgical treatment techniques. Aids the practicing physicians, endocrinologists, trainees, and fellows in understanding the complex concepts in a practical way. Fills the gap in the market for a much-needed book concentrated on endocrine neck diseases of childhood.
Thyroid and Parathyroid Ultrasound and Ultrasound-Guided FNA
by Robert A. Levine Daniel S. Duick Mark A. LupoIn this concise, gold-standard 4th edition book, the volume editors and authors synthesize the prior three editions and provide a comprehensive and expanded review on the latest in the diagnosis and management of thyroid nodules, as well as an update on parathyroid disease and non-endocrine lesions of the neck. This user-friendly edition again emphasizes a multidisciplinary approach to thyroid ultrasound and UGFNA, offering all the new information and subtleties clinicians must know in the application of this technique, now firmly established as a primary tool for diagnosing and managing thyroid disease. Developed by renowned experts in thyroid and parathyroid disease, the book covers not only thyroid and parathyroid disease, but also imaging of the salivary glands and other non-endocrine lesions of the neck. In this edition, the authors expand the chapters on both surgical and non-surgical management. Given the increased use of molecular markers in thyroid evaluation, an excellent chapter addresses this topic. Finally, as more endocrinologists and surgeons perform ultrasounds in their office practices, a chapter on authoring ultrasound reports is now included. Combining the collective wisdom of specialists who treat patients with thyroid nodules, thyroid cancer and parathyroid disease, Handbook of Thyroid and Parathyroid Ultrasound and Ultrasound-Guided FNA, 4th Edition is an invaluable resource and will continue serving as the "go to" guide for surgeons, endocrinologists, fellows and residents. Foreword by Peter A. Singer, MD, Chief of Clinical Endocrinology and Director, Thyroid Diagnostic Center, Keck School of Medicine of USC, Los Angeles, CA.