- Table View
- List View
Tietz Fundamentals Of Clinical Chemistry And Molecular Diagnostics
by Nader RifaiGet the foundational knowledge you need to successfully work in a real-world, clinical lab with Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 8th Edition. From highly respected clinical chemistry expert Nader Rifai, this condensed, easier-to-understand version of the acclaimed Tietz Textbook of Clinical Chemistryand Molecular Diagnostics uses a laboratory perspective to guide you through selecting and performing diagnostic lab tests and accurately evaluating the results. Coverage includes laboratory principles, analytical techniques, instrumentation, analytes, pathophysiology, and more. This eighth edition features new clinical cases from The Coakley Collection, new questions from The Deacon’s Challenge of Biochemical Calculations Collection, plus new content throughout the text to ensure you stay ahead of all the latest techniques, instrumentation, and technologies.
Tiger Woods's Back and Tommy John's Elbow: Injuries and Tragedies That Transformed Careers, Sports, and Society
by Jonathan GelberHow has today’s society changed because of Sandy Koufax, Tom Brady, or Tiger Woods? How have courtrooms and the law changed because of the tragic loss of a No. 1 NBA Draft Pick and a NASCAR driver? And what effect did Magic Johnson’s announcement regarding his HIV diagnosis have on the NBA and testing across the nation? Dr. Jonathan Gelber has compiled a list of impactful injuries and tragedies in Tiger Woods's Back and Tommy John’s Elbow: Injuries and Tragedies That Transformed Careers, Sports, and Society and the ripple effect they have had on players across several different sports and on society in general. Among the athletes featured in this book are:• Tommy John and how the surgery that bears his name may have led to a youth injury epidemic • Dale Earnhardt and how his devastating crash led to new rules and safety concerns for NASCAR and changes in privacy laws • Lyle Alzado and how the conversation on steroids was driven underground • Len Bias and how his death shaped today's drug laws • And many more!
Tight Junctions
by Marcelino Cereijido James AndersonAs the first detailed overview of the subject, Tight Junctions brought together diverse perspectives from leading investigators to provide a multidisciplinary overview of the field. Since its publication in 1992, there has been an explosion of information about tight junctions, particularly in the area of molecular structure, cell and molecular bio
Tight Junctions
by Lorenza González-MariscalThis volume explores the dynamic topic of tight junctions. The book focuses on tight junctions' role in sealing adjacent epithelial cells in a narrow band just beneath their apical surface. The book explains how tight junctions consist of a network of claudins and other proteins, and delves into how they hold cells together and form functional and protective barriers, regulating the passage of molecules and ions through the space between cells.The book opens with a discussion of the evolution of research on tight junctions, discussing a range of primary areas of growth, including the current knowledge on the particular physiological function of different claudins due to the development of an array of knock out mice. The chapters also explore in-depth studies of tight junctions in specific tissues (gut, lung and endothelia). This book offers a comprehensive understanding on post-translational modifications of occludin and its impact on tight junction function, as well as the molecular composition and function of tricellular tight junctions. This volume is particularly relevant to students and scientists in neuroscience, cell biology, physiology, cell differentiation, and cancer research.
Tight Junctions in Cancer Metastasis
by Tracey A. Martin Wen G. JiangThere has been a dramatic increase in knowledge of tight junctions in the past decade. The molecular structure of tight junctions, cellular functions and the pathophysiological roles of tight junctions are becoming clear. Of the most important functions, the role of the cellular structure in cancer spread and drug delivery are increasingly realised. It is now clear that there are fundamental changes to tight junctions during the process of cancer development. Tight junctions are also critical to the metastatic process of cancer cells. The cellular structure is also crucial in drug therapies, namely, the permeability and bioavailability of the drugs, penetration of barriers such as the blood brain barrier. This current volume aims to summarise the current knowledge of tight junctions, their role in cancer and cancer metastasis and is of interest to scientists and clinicians.
Tight Junctions in Inflammation and Cancer
by Ajaz A. Bhat Mohammad Haris Muzafar A. Macha Punita DhawanThis book provides an updated account of tight junctions of different epithelia and endothelia and addresses their anatomy, biochemistry, physiology, synthesis, assembly, and modulation. It also discusses the relationship between molecular structure, function, regulation, posttranslational modifications of tight junction proteins and their role in gut microbiota maintenance, epithelial-mesenchymal transition, and intestinal barrier dysfunction-associated disorders important for the progression of human cancers. This book presents the pathological alterations of tight junctions at the blood-brain barrier that intensify or even initiate neurological dysfunction. Further, it reviews the significance of tight junctions and tight junction proteins in cancer development, infectious diseases, allergic reactions, and autoimmune disorders. Lastly, it highlights strategies for modulating tight junctions to enhance drug availability and organ deposition. This book is immensely useful for basic, translational, clinical, and interdisciplinary cancer researchers, practicing oncologists, and immunologists.
Tigliane Diterpenoids (Progress in the Chemistry of Organic Natural Products #125)
by A. Douglas Kinghorn Heinz Falk Simon Gibbons Yoshinori Asakawa Ji-Kai Liu Verena M. DirschThis book reviews the distribution, chemistry, and molecular bioactivity of tiglianes from the very beginning of the studies on these diterpenoids. It provides a summary of their clinical and toxicological literature mostly in its more recent and controversial aspects, while critically analyzing various proposals for their biosynthesis.
Tiling Arrays: Methods and Protocols
by Tin-Lap Lee Alfred Chun Shui LukIn Tiling Arrays: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to study tiling microarrays in genomic discovery . These include methods and applications for transcriptional regulation, expression, genetic and epigenetic regulation, as well as techniques and skills on tiling microarray data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Tiling Arrays: Methods and Protocols seeks to provide scientists with a comprehensive and down to earth approach to maximize results.
TIMBER Psychotherapy: For PTSD, Depression and Traumatic Psychosis
by Shanaya Rathod Basant Pradhan Narsimha R. PinnintiTIMBER psychotherapy is a novel, translational and biomarker informed, mindfulness-based cognitive behavioral therapy approach that addresses some of the current treatment gaps for PTSD, depression and traumatic psychosis. This treatment manual offers practitioners and patients alike a step-by-step guide to TIMBER (acronym for Trauma Interventions using Mindfulness Based Extinction and Reconsolidation of memories) psychotherapy, and has been divided into four parts: Understanding Complex Trauma and Traumatic Psychosis; Methodology and Application; Training Professionals; and Policy Implications & Future Research Directions. In addition to a strong rationale and evidence base for the TIMBER approach, the book also provides case examples accompanied by videos (available separately). Its special features include reproducible client handouts, assessment tools, and a list of resources for training to use TIMBER.
Timbre: Acoustics, Perception, and Cognition (Springer Handbook of Auditory Research #69)
by Kai Siedenburg Charalampos Saitis Stephen McAdams Arthur N. Popper Richard R. FayRoughly defined as any property other than pitch, duration, and loudness that allows two sounds to be distinguished, timbre is a foundational aspect of hearing. The remarkable ability of humans to recognize sound sources and events (e.g., glass breaking, a friend’s voice, a tone from a piano) stems primarily from a capacity to perceive and process differences in the timbre of sounds. Timbre raises many important issues in psychology and the cognitive sciences, musical acoustics, speech processing, medical engineering, and artificial intelligence. Current research on timbre perception unfolds along three main fronts: On the one hand, researchers explore the principal perceptual processes that orchestrate timbre processing, such as the structure of its perceptual representation, sound categorization and recognition, memory for timbre, and its ability to elicit rich semantic associations, as well as the underlying neural mechanisms. On the other hand, timbre is studied as part of specific scenarios, including the perception of the human voice, as a structuring force in music, as perceived with cochlear implants, and through its role in affecting sound quality and sound design. Finally, computational acoustic models are sought through prediction of psychophysical data, physiologically inspired representations, and audio analysis-synthesis techniques. Along these three scientific fronts, significant breakthroughs have been achieved during the last decade. This volume will be the first book dedicated to a comprehensive and authoritative presentation of timbre perception and cognition research and the acoustic modeling of timbre. The volume will serve as a natural complement to the SHAR volumes on the basic auditory parameters of Pitch edited by Plack, Oxenham, Popper, and Fay, and Loudness by Florentine, Popper, and Fay. Moreover, through the integration of complementary scientific methods ranging from signal processing to brain imaging, the book has the potential to leverage new interdisciplinary synergies in hearing science. For these reasons, the volume will be exceptionally valuable to various subfields of hearing science, including cognitive auditory neuroscience, psychoacoustics, music perception and cognition, but may even exert significant influence on fields such as musical acoustics, music information retrieval, and acoustic signal processing.It is expected that the volume will have broad appeal to psychologists, neuroscientists, and acousticians involved in research on auditory perception and cognition. Specifically, this book will have a strong impact on hearing researchers with interest in timbre and will serve as the key publication and up-to-date reference on timbre for graduate students, postdoctoral researchers, as well as established scholars.
Timby's Fundamental Nursing Skills And Concepts
by Loretta A. Donnelly-MorenoThe Twelfth Edition of Timby’s Fundamental Nursing Skills and Concepts continues the tradition of excellent coverage of basic nursing theory and clinical skills that have long made this text a leading resource for LPN/LVN students at the beginning of their program, as well as a comprehensive reference for updating the skills of currently employed nurses or those returning to work after a period of inactive practice. Students using this text will learn theoretical nursing concepts, step-by-step skills and procedures, and clinical applications, all while applying philosophical concepts focusing on the human experience, such as caring as the essence of nursing, supportive health care provider networks, and accountability for actions and clinical decisions. Engaging learning tools promote critical thinking, and visually enticing photos and illustrations bring the information to life to reinforce learning. Updated to help students meet the needs of today’s changing healthcare environment, this new edition reflects the most current medical and nursing practices, including up-to-date gerontologic, pharmacologic, and nutritional considerations and the latest NANDA diagnoses and terminology
Timby's Introductory Medical-Surgical Nursing: .
by Loretta A. Donnelly-Moreno Brigitte MoseleyApproachable, comprehensive, and optimized for today’s visual learners, Timby’s Introductory Medical-Surgical Nursing, 13th Edition, clarifies the challenging field of medical-surgical nursing and gives LPN/LVN students the understanding and clinical judgment to deliver safe, effective patient care. The updated 13th Edition combines clear writing, dynamic photographs and illustrations, engaging study tools, and robust online resources to equip students with the confidence and understanding for superior clinical success in a changing healthcare environment.
TIME 100 Healthiest Foods to Satisfy Your Hunger
by The Editors of TIMEMany of the most filling foods available are also some of the healthiest. This book contains a list of 100 of the most satisfying, hunger-quelling foods that are easy to find and taste great!
Time and Performer Training
by Mark Evans Konstantinos Thomaidis Libby WorthTime and Performer Training addresses the importance and centrality of time and temporality to the practices, processes and conceptual thinking of performer training. Notions of time are embedded in almost every aspect of performer training, and so contributors to this book look at: age/aging and children in the training context how training impacts over a lifetime the duration of training and the impact of training regimes over time concepts of timing and the ‘right’ time how time is viewed from a range of international training perspectives collectives, ensembles and fashions in training, their decay or endurance. Through focusing on time and the temporal in performer training, this book offers innovative ways of integrating research into studio practices. It also steps out beyond the more traditional places of training to open up time in relation to contested training practices that take place online, in festival spaces and in folk or amateur practices. Ideal for both instructors and students, each section of this well-illustrated book follows a thematic structure and includes full-length chapters alongside shorter provocations. Featuring contributions from an international range of authors who draw on their backgrounds as artists, scholars and teachers, Time and Performer Training is a major step in our understanding of how time affects the preparation for performance.
Time and the Brain (Conceptual Advances in Brain Research)
by Ian MuehlenhausSince the days of Galileo, time has been a fundamental variable in scientific attempts to understand the natural world. Once the first recordings of electrical activity in the brain had been made, it became clear that electrical signals from the brain consist of very complex temporal patterns. This can now be demonstrated by recordings at the singl
Time Delay ODE/PDE Models: Applications in Biomedical Science and Engineering
by W.E. SchiesserTime delayed (lagged) variables are an inherent feature of biological/physiological systems. For example, infection from a disease may at first be asymptomatic, and only after a delay is the infection apparent so that treatment can begin.Thus, to adequately describe physiological systems, time delays are frequently required and must be included in the equations of mathematical models. The intent of this book is to present a methodology for the formulation and computer implementation of mathematical models based on time delay ordinary differential equations (DODEs) and partial differential equations (DPDEs). The DODE/DPDE methodology is presented through a series of example applications, particularly in biomedical science and engineering (BMSE). The computer-based implementation of the example models is explained with routines coded (programmed) in R, a quality, open-source scientific computing system that is readily available from the Internet. Formal mathematics isminimized, e.g., no theorems and proofs. Rather, the presentation is through detailed examples that the reader/researcher/analyst can execute on modest computers. The DPDE analysis is based on the method of lines (MOL), an established general algorithm for PDEs, implemented with finite differences. The example applications can first be executed to confirm the reported solutions, then extended by variation of the parameters and the equation terms, and even the forumulation and use of alternative DODE/DPDE models. • Introduces time delay ordinary and partial differential equations (DODE/DPDEs) and their numerical computer-based integration (solution) • Illustrates the computer implementation of DODE/DPDE models with coding (programming) in R, a quality, open-source scientific programming system readily available from the Internet • Applies DODE/DPDE models to biological/physiological systems through a series of examples • Provides the R routines for all of the illustrative applications through a download link • Facilitates the use of the models with reasonable time and effort on modest computers
Time for Dying
by Graham McAleerThis book has been written for those who must work with and give care to the dying. Our discussion is not simple narrative or description; it is a ""rendition of reality,"" informed by a rather densely woven and fairly abstract theoretical scheme. This scheme evolved gradually during the course of our research. The second audience for this volume is social scientists who are less interested in dying than they are in useful substantive theory. Our central concern is with the temporal aspects of work. The theory presented here may be useful to social scientists interested in areas far removed from health, medicine, or hospitals. The training of physicians and nurses equips them for the technical aspects of dealing with illness.Medical students learn not to kill patients through error, and to save lives through diagnosis and treatment. But their teachers put little or no emphasis on how to talk with dying patients; how-or whether-to disclose an impending death; or even how to approach the subject with the wives, husbands, children, and parents of the dying. Students of nursing are taught how to give nursing care to terminal patients, as well as how to give ""post-mortem care."" But the psychological aspects of dealing with the dying and their families are virtually absent from training. Although physicians and nurses are highly skilled at handling the bodies of terminal patients, their behavior to them otherwise is actually outside the province of professional standards. Much, if not most, nontechnical conduct toward, and in the presence of, dying patients and their families is profoundly influenced by ""common sense"" assumptions, essentially untouched by professional or even rational considerations or by current advancement in social-psychological knowledge. The process of dying in hospitals is much affected by professional training and codes, and by the particular conditions of work generated by hospitals as places of work. A third important consideration in int
TIME Innocent: The Fight Against Wrongful Convictions
by The Editors of TIMETIME looks at those wrongfully convicted, and the fight to set them free.
The Time is Now: A Contemporary Medical Romance (Medical Romances #20)
by Gill SandersonAnother heartwarming medical romance from best-selling author Gill Sanderson! Perfect for fans of Mia Faye, Laura Scott, Helen Scott Taylor, Grey's Anatomy and ER.Readers love Gill's gripping medical romances!'What a truly gifted writer! Highly recommended!!' 5* reader review'Yet another lovely story I enjoyed' 5* reader review'Remarkable writer!!' 5* author review It's Scrub nurse Jane Cabot's twenty-ninth birthday and she would like to be married before she is thirty. Her life is full - theatre nurse, Samaritan's Counsellor, choir member, hockey player - but so far she has not found the right man. Could the new anaesthetist David Kershaw be the one? He's a good worker, thoughtful of staff and patients, obviously interested in her - and drop-dead gorgeous. But she has been warned about him. He only likes casual relationships.As she gets to know him she realises that he has problems - as she does herself. Could they solve their problems together?Don't miss Gill Sanderson's enthralling medical romances, including the A Lakeland Practice and the Good, Bad and Ugly series.
The Time is Now: A Contemporary Medical Romance (Medical Romances Ser.)
by Gill SandersonAnother heartwarming medical romance from best-selling author Gill Sanderson! Perfect for fans of Mia Faye, Laura Scott, Helen Scott Taylor, Grey's Anatomy and ER.Readers love Gill's gripping medical romances!'What a truly gifted writer! Highly recommended!!' 5* reader review'Yet another lovely story I enjoyed' 5* reader review'Remarkable writer!!' 5* author review It's Scrub nurse Jane Cabot's twenty-ninth birthday and she would like to be married before she is thirty. Her life is full - theatre nurse, Samaritan's Counsellor, choir member, hockey player - but so far she has not found the right man. Could the new anaesthetist David Kershaw be the one? He's a good worker, thoughtful of staff and patients, obviously interested in her - and drop-dead gorgeous. But she has been warned about him. He only likes casual relationships.As she gets to know him she realises that he has problems - as she does herself. Could they solve their problems together?Don't miss Gill Sanderson's enthralling medical romances, including the A Lakeland Practice and the Good, Bad and Ugly series.
Time, Life & Memory: Bergson and Contemporary Science (Library of Ethics and Applied Philosophy #38)
by Laurens LandeweerdThis book revitalizes the relevance of the ideas of Henri Bergson (1859-1941) for current developments in exact sciences. It explores the relevance of Bergson's thought for contemporary philosophical reflections on three of the most important scientific research areas of today, namely physics, the life sciences and the neurosciences. It does so on the basis of the three interrelated topics of time, life and memory. Henri Bergson (1859-1941) was one of the most widely read philosophers of his era. The European public was seeking for answers to questions of the soul and the nature of life and fitting within a historical niche between intellectual rationalism and intuitive spiritualism, his writings drew much attention. This work focuses on the relevance of his philosophy for developments in exact sciences today. The discussion of physics in relation to the abstract and the concrete, the life sciences in relation to concepts of life in relation to new and emerging biotechnology, and the neurosciences in relation to the dual nature of human identity, focuses on one main topic: time. Time, isolated from experience, as the measure of the events in the universe in modern physics; time as the measure of emergent systems in evolution as the backdrop of the theory of evolution in biology; time in relation to memory and imagination in neuropsychological accounts of memory. The author thus discusses the ideas of Henri Bergson as a basis to unveil time as a living process, rather than as an instrument for the measure of events. This view forms the basis of a novel approach to the philosophy of technology. An exciting book for academics interested in the interplay between hard sciences and philosophy.
Time Limited Therapy in Primary Care: A Person-Centred Dialogue (Living Therapies Series)
by Richard Bryant-Jefferies"Many counsellors who work in primary care find it difficult to explain to colleagues in the primary care team what they actually do with clients behind the closed door of their room. In this book the author brings to life in a gripping way what really does go on when a counsellor sees a patient in the primary healthcare setting. It’s good to read for once a book that describes so realistically and movingly the minute-by-minute account of what actually happens, not a book describing clever therapists getting it right all the time. The book should be required reading for newly appointed non-clinical managers of counselling services and for primary healthcare staff about to start working with a counsellor as a member of their team."— Graham Curtis Jenkins in his Foreword
TIME Marijuana: The Medical Movement
by The Editors of TIMECanabis has been used as medicine for 4,000 years. Now, with the majority of states legalizing medical marijuana, the U.S. is discovering this plant's full potential. Discover more in TIME Marijuana: The Medical Movement.
TIME Marijuana Goes Mainstreet: A Booming Business - Your Brain on Pot - Legalization Marches On
by Bruce BarcottWelcome to the end of the war on pot. With more landmark legislation in 2016, marijuana has continued its march toward legalization and normalization, 29 states having gone medically legal. In this updated adaptation, based on Bruce Barcott's groundbreaking book Weed the People, we look at some of the key issues surrounding pot:What benefits has it shown in treating conditions ranging from glaucoma to multiple sclerosis to PTSD? How did it come to be classified as a Schedule I drug?Who are the harvesters, investors and entrepreneurs bringing pot out of the shadows and grow rooms and into the marketplace?How does such a marketplace come to exist amid a complicated regulatory framework?Where do we go from here, at a time when states are increasingly pro-legalization but a new federal administration could change things at any time?
A Time of Scandal: Charles R. Forbes, Warren G. Harding, and the Making of the Veterans Bureau
by Rosemary StevensWas the founding director of the US Veterans Bureau a criminal—or a scapegoat?In the early 1920s, with the nation still recovering from World War I, President Warren G. Harding founded a huge new organization to treat disabled veterans: the US Veterans Bureau, now known as the Department of Veterans Affairs. He appointed his friend, decorated veteran Colonel Charles R. Forbes, as founding director. Forbes lasted in the position for only eighteen months before stepping down under a cloud of criticism and suspicion. In 1926—after being convicted of conspiracy to defraud the federal government by rigging government contracts—he was sent to Leavenworth Penitentiary. Although he was known in his day as a drunken womanizer, and as a corrupt, betraying toady of a weak, blind-sided president, the question persists: was Forbes a criminal or a scapegoat? Historian Rosemary Stevens tells Forbes’s story anew, drawing on previously untapped records to reveal his role in America’s initial and ongoing commitment to veterans. She explores how Forbes’s rise and fall in Washington illuminates President Harding’s efforts to bring business efficiency to government. She also examines the Veterans Bureau scandal in the context of class, professionalism, ethics, and etiquette in a rapidly changing world. Most significantly, Stevens proposes a fascinating revisionist view of both Forbes and Harding—and raises questions about not only the validity but the source of their respective reputations. They did not defraud the government of billions of dollars, Stevens convincingly documents, and do not deserve the reputation they have carried for a hundred years.Packed with vibrant characters—conniving friends, FBI agents, and rival politicians split by sectional and ideological interests as well as gamblers, revelers, and wronged wives—A Time of Scandal will appeal to anyone interested in political gossip, presidential politics, the "Ohio Gang," and the 1920s.