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Willful Ignorance
by Herbert I. WeisbergAn original account of willful ignorance and how this principle relates to modern probability and statistical methods Through a series of colorful stories about great thinkers and the problems they chose to solve, the author traces the historical evolution of probability and explains how statistical methods have helped to propel scientific research. However, the past success of statistics has depended on vast, deliberate simplifications amounting to willful ignorance, and this very success now threatens future advances in medicine, the social sciences, and other fields. Limitations of existing methods result in frequent reversals of scientific findings and recommendations, to the consternation of both scientists and the lay public.Willful Ignorance: The Mismeasure of Uncertainty exposes the fallacy of regarding probability as the full measure of our uncertainty. The book explains how statistical methodology, though enormously productive and influential over the past century, is approaching a crisis. The deep and troubling divide between qualitative and quantitative modes of research, and between research and practice, are reflections of this underlying problem. The author outlines a path toward the re-engineering of data analysis to help close these gaps and accelerate scientific discovery. Willful Ignorance: The Mismeasure of Uncertainty presents essential information and novel ideas that should be of interest to anyone concerned about the future of scientific research. The book is especially pertinent for professionals in statistics and related fields, including practicing and research clinicians, biomedical and social science researchers, business leaders, and policy-makers.
William Blake's Visions: Art, Hallucinations, Synaesthesia (Palgrave Studies in Literature, Science and Medicine)
by David WorrallThis book is an inquiry into whether what Blake called his ‘visions’ can be attributed to recognizable perceptual phenomena. The conditions identified include visual hallucinations (some derived from migraine aura), and auditory and visual hallucinations derived from several types of synaesthesia. Over a long period of time, Blake has been celebrated as a ‘visionary,’ yet his ‘visions’ have not been discussed. Worrall draws on an understanding of neuroscience to examine both Blake’s visual art and writings, and discusses the lack of evidence pointing towards psychosis or pathological ill-health, thus questioning the rumours pertaining to Blake’s insanity.
William James, MD: Philosopher, Psychologist, Physician
by Emma K. SuttonThe first book to map William James’s preoccupation with medical ideas, concerns, and values across the breadth of his work. William James is known as a nineteenth-century philosopher, psychologist, and psychical researcher. Less well-known is how his interest in medicine influenced his life and work, driving his ambition to change the way American society conceived of itself in body, mind, and soul. William James, MD offers an account of the development and cultural significance of James’s ideas and works, and establishes, for the first time, the relevance of medical themes to his major lines of thought. James lived at a time when old assumptions about faith and the moral and religious possibilities for human worth and redemption were increasingly displaced by a concern with the medically “normal” and the perfectibility of the body. Woven into treatises that warned against humanity’s decline, these ideas were part of the eugenics movement and reflected a growing social stigma attached to illness and invalidism, a disturbing intellectual current in which James felt personally implicated. Most chronicles of James’s life have portrayed a distressed young man, who then endured a psychological or spiritual crisis to emerge as a mature thinker who threw off his pallor of mental sickness for good. In contrast, Emma K. Sutton draws on his personal correspondence, unpublished notebooks, and diaries to show that James considered himself a genuine invalid to the end of his days. Sutton makes the compelling case that his philosophizing was not an abstract occupation but an impassioned response to his own life experiences and challenges. To ignore the medical James is to misread James altogether.
Williams' Essentials of Nutrition and Diet Therapy 11th Edition
by Eleanor Schlenker Joyce GilbertFrom basic nutrition principles to the latest nutrition therapies for common diseases, Williams' Essentials of Nutrition & Diet Therapy, 11th Edition offers a solid foundation in the fundamental knowledge and skills you need to provide effective patient care. Authors Eleanor Schlenker and Joyce Gilbert address nutrition across the lifespan and within the community, with an emphasis on health promotion and the effects of culture and religion on nutrition. Evidence-based information, real-world case scenarios, colorful illustrations, boxes, and tables help you learn how to apply essential nutrition concepts and therapies in clinical practice.
Williams Gynecology, Second Edition
by Barbara L. Hoffman John O. Schorge Joseph I. Schaffer Lisa M. Halvorson Karen D. Bradshaw F. Gary Cunningham Lewis E. CalverWilliams Gynecology provides a thorough presentation of gynecology's depth and breadth. In Section 1, general gynecology topics are covered. Sections 2 provides chapters covering reproductive endocrinology and infertility. The developing field of Female Pelvic Medicine and Reconstructive Surgery is presented in Section 3. In Section 4, gynecologic oncology is discussed.
Williams Obstetrics, Twenty-Fourth Edition
by F. Gary Cunningham Kenneth J. Leveno Steven L. Bloom Catherine Y. Spong Jodi S. Dashe Barbara L. Hoffman Brian M. Casey Jeanne S. SheffieldWilliams Obstetrics is the most detailed, comprehensive, and rigorously referenced text on the subject. Written by an author team from the world-renowned Parkland Hospital, the hallmarks of this classic are its thoroughness, scientific basis, and practical applicability for the obstetrician at the bedside. This edition of Williams Obstetrics continues to emphasize the scientific-based underpinnings and evidence-based practices of the specialty. This is accomplished by using incorporating more than 3,000 new literature citations and guidelines from the most trusted professional and academic organizations.
Williams Textbook of Endocrinology 13th Edition
by Shlomo Melmed Kenneth S. Polonsky P. Reed Larsen Henry M. KronenbergThe 13th edition is updated to bring you state-of-the-art coverage of diabetes, metabolic syndrome, obesity, thyroid disease, testicular disorders, and much more, all designed to help you provide optimal care to every patient.
Willow Weep for Me: A Black Woman's Journey Through Depression
by Nana-Ama DanquahThe first book to focus on Black women and depression, through the author’s “absorbing and inspirational” (Washington Post) personal journey. When Nana-Ama Danquah, a twenty-two-year-old single mother, began to suffer from a variety of depressive symptoms after giving birth to her daughter, she thought she was going crazy. Determined to portray strength in a world that often undervalues Black women’s lives, she shrouded her debilitating despair in silence and denial. But when she befriends other Black women who suffer with depression, she finds the support she needs to confront the traumatic childhood events that lie beneath her grief. Twenty-five years after its initial publication, as best-selling author Andrew Solomon writes in an illuminating foreword, Willow Weep for Me “remains a brave book . . . but at the time of its writing it was humblingly audacious.” Also including an afterword from the author, this groundbreaking classic is a powerful meditation on courage and a litany for survival. “An important and moving memoir. [Danquah] describes beautifully her experiences with depression.” —Kay Redfield Jamison, author of An Unquiet Mind
The Willowbrook Wars: Bringing the Mentally Disabled into the Community
by David J. RothmanThe Willowbrook Wars is a dramatic and illuminating account of the effort to close down a scandal-ridden institution and return its 5,400 handicapped residents to communities in New York. The wars began in 1972 with Geraldo Rivera's televised raid on the Willowbrook State School. They continued for three years in a federal courtroom, with civil libertarian lawyers persuading a conservative and conscience-stricken judge to expand the rights of the disabled, and they culminated in a 1975 consent decree, with the state of New York pledging to accomplish the unprecedented assignment in six years.From 1975 to 1982, David and Sheila Rothman observed this remarkable chapter in American reform of mental disabilities care. Would the state live up to its agreement without "dumping" residents into other nightmarish institutions? Would the lawyers prove as interested in meeting client needs as in securing client rights? Could a tradition-bound bureaucracy create a new network of community services? And finally, would a governor and a legislature tolerate such outside intervention, and if so, for how long? In answering these questions,The Willowbrook Wars takes us behind the scenes to clarify the role of the judiciary, the fate of the underprivileged, and the potential for social justice. In their new afterword, the authors bring the story up to date, describing the results of the closing of the institution in 1987 from the experiences of integrating the former residents into communities to the legal battles between the state of New York and advocates for the mentally handicapped.
The Wills Eye Manual: Office and Emergency Room Diagnosis and Treatment of Eye Disease
by Kalla Gervasio Travis PeckA best-selling source of compact, authoritative guidance on the treatment of ocular disorders in a variety of settings, The Wills Eye Manual, 8th Edition, is the comprehensive, high-yield reference of choice for both trainees and seasoned practitioners. It provides highly illustrated information on more than 200 ophthalmic conditions along with proven clinical recommendations from initial diagnosis through extended treatment. The consistent, bulleted outline format makes it ideal for portability and quick reference.
The Wills Eye Strabismus Surgery Handbook
by Leonard Nelson Alex LevinAlthough residents and pediatric ophthalmology fellows examine patients in the clinic, they may not be involved in surgery on the same patients and even less often get to follow the progress of these patients postoperatively. The Wills Eye Strabismus Surgery Handbook is designed to address this challenge in residency and fellowship education as a manual focused on developing surgical plans for strabismus patients. Drs. Leonard B. Nelson and Alex V. Levin and their contributors have organized The Wills Eye Strabismus Surgery Handbookto allow for the reader to take notes regarding their own diagnosis and treatment plan for each case that is presented. This workbook style and its practical, easy-to-read format make this resource useful for written and oral board preparation, and as a handy reference guide for use long after exams are over. Each chapter presents an introduction into the decision-making process for a specific strabismus condition, followed by the surgical plans selected by three expert Wills Eye Strabismus Center strabismologists with regard to their approach to the presented case. Summary remarks by the chapter editor briefly review the basic concepts in developing a diagnosis and treatment plan while bringing together the varied opinions offered by the strabismologists in order to put them in context.Topics covered include: Strabismus surgery decision making Esotropia Exotropia Dissociated vertical deviation Cranial nerve palsies Strabismus syndromes Strabismus in systemic disease Reoperations Nystagmus Other complex strabismus cases The Wills Eye Strabismus Surgery Handbook is an essential resource for residents and pediatric ophthalmology fellows, as well as other ophthalmologists, looking to develop their surgical planning skills. It is a helpful field guide for any ophthalmologists who does strabismus and who is looking for a handy addition to their reference shelf.
Wilms’ Tumor
by Yogesh Kumar SarinThis book covers all aspects of Wilms’ tumor, the second most typical solid tumor in children. Its potential for complete cure underscores correct management of this tumor. To achieve this goal, the book aims to provide all necessary details for practicing Pediatric surgeons, Oncologists, Pediatricians, Urologists, and Medical students. Topics ranging from epidemiology, etiology, pathology, clinical features, diagnostic methods, surgery, chemotherapy, radiotherapy to cutting-edge inventions are described in great detail.Detailed descriptions of surgical techniques and their nuances will greatly benefit surgeons and surgical residents. Importantly, all the chapters are written by authors who have first-hand experience with clinical management. Thus the text ensures the practical application of theoretical details.
The Wilms' Tumor (WT1) Gene
by Nicholas HastieThis volume provides a thorough overview of the Wilms Tumour Gene (WT1). The book begins with three review chapters that cover the involvement of WT1 in pediatric cancer, kidney disease, and tissue development and homeostasis. The next few chapters discuss cell marking and lineage tracing, epicardial cell methodology, colony forming assays for bone marrow stem cells, angiogenesis assays and zebrafish tools. The next group of chapters explores the latest tools in genomics, molecular biology, and biochemistry. They discuss dissecting transcription factor function in cell free systems, ChiP seq, proteomics, RNA interactome, and multiphoton imaging of lipids, measuring the binding constants of protein-nucleic acid interactions, and bioinformatics approaches for analyzing Next Generation Sequence data. The final chapter discusses protocols for clinical trials for immune therapy using anti-WT1 peptides. Written in the highly successful "Methods in Molecular Biology" series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and thorough, "The Wilms Tumour (WT1) Gene: Methods and Protocols" is a valuable resource for anyone who is interested in the diverse methodologies used in WT1 research. "
Windows to the Womb: Revealing the Conscious Baby from Conception to Birth
by David ChamberlainWindows to the Womb is an eloquent guide through the first nine months of life from conception to birth. In the past, the invisible physical processes of fetal development were mysterious and largely unexplainable, but in the past half-century, breakthroughs in embryology, interuterine photography, ultrasound, and other sensitive instruments of measurement have enabled us to make systematic observations inside the womb. We now understand that fetuses are fully sentient and aware beings. In this new climate of appreciation for the surprising dimensions of fetal behavior, sensitivity, and intelligence, this book brings a host of new information to light about the transformative journey each one of us must undergo in the womb.With reverent awe, the author describes the amazing construction of our physical bodies, the "ultimate architecture," and draws parallels with the expansion of our minds as our brains and senses develop and grow. Dr. Chamberlain details new discoveries in embryonic and fetal research that support his own findings on the impact of the mother's emotional and physical state during pregnancy; the importance of bonding at the earliest stages, long before birth; and the steps that expectant parents can take to ensure the most nurturing start in life for their children.From the Trade Paperback edition.
The Wine-Dark Sea Within: A Turbulent History of Blood
by Dr. Dhun SethnaA revisionist history of medicine, in which blood plays the starring role Inspired by Homer&’s description of the ebb and flow of the &“wine dark sea,&” the ancient Greeks conceived a back-and-forth movement of blood. That false notion, perpetuated by the influential Roman physician Galen, prevailed for fifteen hundred years until William Harvey proved that blood circulates: the heart pumps blood in one direction through the arteries and it returns through the veins. Harvey&’s discovery revolutionized the life sciences by making possible an entirely new quantitative understanding of the cardiovascular system, a way of thinking on which many of our lifesaving medical interventions today depend. In The Wine-Dark Sea Within, cardiologist Dhun Sethna argues that Harvey&’s revelation inaugurated modern medicine and paved the way for groundbreaking advances from intravenous therapy, cardiac imaging, and stent insertions to bypass surgery, dialysis, and heart-lung machines. Weaving together three thousand years of global history, following bitter feuds and epic alliances, tragic failures and extraordinary advancements, this is a provocative history by a fresh voice in popular science.
Winged Scalpel: A Surgeon at the Frontline of Disaster
by Richard VillarAn ex-SAS surgeon&’s gripping memoir of trying to save lives in disaster areas and war zones around the globe. In this fast-paced narrative, ex-SAS surgeon Richard Villar provides a very personal insight into the difficulties, dangers, and occasional virtual impossibility of providing medical aid to disaster areas and war zones. He shares his remarkable experiences in the aftermath of three major earthquakes Kashmir (2005), Java (2006), and Haiti (2010) as well as in the 2011 Libyan civil war, in a no-holds-barred introduction to a world most will never experience. He describes what happens on the ground before a full aid program swings into action. Arriving in a stricken area with the infrastructure destroyed, his small, dedicated team can take nothing for granted; water, power, shelter, and the rule of law are likely to be nonexistent and disease and shortages of food and water ever present. They meet challenges that the rest of us can only imagine and are under intense pressure to help, comfort, and sustain overwhelming numbers of traumatized men, women, and children whose worlds have been turned upside down. Winged Scalpel is not only a riveting read but highly instructional and informative. From his own point of view, the author&’s experiences prove that you can take a man out of the SAS, but you cannot take the SAS out of the man.
Winnicott and Kohut on Intersubjectivity and Complex Disorders: New Perspectives for Psychoanalysis, Psychotherapy and Psychiatry
by Carlos NemirovskyGiven the complexity of scientific developments inside and outside the psychoanalytic field, traditional definitions of basic psychoanalytic notions are no longer sufficiently comprehensive. We need conceptualizations that encompass new clinical phenomena observed in present-day patients and that take into account contributions inside, outside, and on the boundaries of our practice. This book discusses theoretical concepts which explain current clinical expressions that are as ineffable as they are commonplace. Our patients resort to these expressions when they feel distressed by their perception of themselves as unreal, empty, fragile, non-existent, non-desiring, doubtful about their identity, beset by feelings of futility and apathy, and emotionally numb. The book aims at contrasting the ideas of Winnicott and Kohut, which are connected with a clinical practice that sees each patient as unique and are moreover in direct contact with empirical facts, and applies them to the benefit of complex patients. These ideas facilitate the expansion of paths in both the theory and the practice of our profession. Uniquely contrasting the works of two seminal thinkers with a Latin American perspective, Winnicott and Kohut on Intersubjectivity and Complex Disorders will be invaluable to clinicians and psychoanalysts.
Winning Back His Doctor Bride
by Tina BeckettThe one that got away Dr. James Rothsberg, renowned plastic surgeon and owner of the Hollywood Hills Clinic, is famous for his control. But then he finds himself working with beautiful Dr. Mila Brightman-the woman he left at the altar six years ago! They're drawn together again by an orphaned patient, and it's not long before the lingering chemistry between them explodes. Now James must decide whether to run again or fight for the woman he never stopped loving!
Winning Back His Runaway Wife
by Louisa GeorgeWill a second chance be in the cards when a doctor is reunited out of the blue with her ex-husband? Find out in Louisa George&’s latest medical romance! HER RETURN COULD BE HIS REDEMPTION… Paramedic Lewis has never forgiven himself for how his marriage to ER doc Charlotte ended. Their fertility challenges drove such a wedge between them that Charlie left, taking a big piece of Lewis with her. But when she unexpectedly takes a job at his hospital, it&’s clear their connection still burns brightly. And this time, Lewis is determined to win back the wife he&’s never forgotten!From Harlequin Medical: Life and love in the world of modern medicine.
Winning Grants (AAPS Introductions in the Pharmaceutical Sciences #17)
by Sean EkinsAs an academic or a small business owner, you will need to write grants at some point in your career. Writing them though is not enough, what you also need to know is how to win grants. Much has been written about writing grants, the mysterious special ability called ‘grantsmanship’, so it occurred to me that there is a need to come at this differently and spill the beans. The difficulty in getting a grant, in particular an NIH grant like an R01 in the USA is often described, it is competitive and gets tougher every year. Your proposal therefore must stand out, it must connect with the reviewers. This is true for all types of grants, give the reviewer what they want always. But also, you need to connect to the program officer, the committee that ultimately makes funding decisions and you must take care of a myriad of other details outside of the main event which is describing the “science”. This means you cannot rely on just out-writing the competition, it is more than that as you have to out-think, out-strategize and out-schmooze them. If you have been continually funded for decades that is terrific, but if you want to keep being funded there is no guarantee what got you there will keep you there. What was a hot technology 4-5 years ago is not the new thing anymore, you will need to do something different, but what? You therefore need to not only think about writing great grants, you need to put it into practice and win them. Having written and won grants from the NIH and DOD over the past 17 years (and longer by the time you read this) I possess a valuable perspective.Each grant and study section will be different. Whether a big or small grant it does not seem to make a difference the reviewers will critique your efforts, they may not like it, they may reject your ideas or they may love it. You have some small degree of control until the proposal leaves your hands or more correctly you click ‘submit’. You will need to differentiate your grant from the hundreds of others in many ways, but you cannot change who you are, your history so how you describe yourself and team will also have an impact. You could spend hundreds of hours on your proposal or just a day and the outcome might still be the same. This small book is a summary of my own personal experiences and will provide some advice that will help you learn how to do a better job of winning grants.This book is written by a scientist who writes the grants and develops commercial products;Provides a unique perspective on what you need to write better grants;Teaches you how to continually win grants;This book provides examples from the authors own grant applications;The reader will be inspired to start a company to win small business grants.
Winning Over the Off-Limits Doctor
by Annie ClaydonThere&’s an instant spark between them, but can these doctors learn to open their guarded hearts? Find out in Annie Claydon&’s latest story for Harlequin Medical Romance. A PRIZE WORTH FIGHTING FOR? To protect her adopted parents from pain, pediatric emergency doc Mattie has worked hard to conceal her more impulsive side. And yet the arrival of charming orthopedic consultant Dr. Llwyd sees her throwing caution to the wind! Llwyd clearly feels the same instant attraction, but the shadows of past trauma haunting his eyes put him firmly off-limits. Unless Mattie&’s zest for life can win him over, and convince guarded Llwyd to take one final risk…From Harlequin Medical: Life and love in the world of modern medicine.
Winning Strategies for Successful Aging (Yale University Press Health & Wellness)
by Eric Pfeiffer&“A work of inspiration and pragmatism&” offering heartening advice on navigating the later years of life for aging individuals and their families (Gary J. Kennedy, M.D., Professor and Director of Geriatric Psychiatry, Montefiore Medical Center, Albert Einstein College of Medicine). For anyone who is approaching a 65th birthday with trepidation, Dr. Eric Pfeiffer, who for thirty years has cared for—and learned from—elderly people, addresses with compassion and deep understanding the multitude of issues that arise. He writes authoritatively but in a conversational tone. His advice is easy to read, easy to follow, and full of wisdom. In short, practical chapters, Dr. Pfeiffer advises on choosing an ideal place to live, finding a range of satisfying activities, and maintaining an active social life. He also explains how best to maintain one&’s health, mental health, wealth, and independence. Other chapters explore the importance of a spiritual life and the value of maintaining an active sexual life. In addition, the author speaks to the value of charitable giving and describes how it is possible to prepare for a good good-bye to life. Filled with illustrative anecdotes and enhanced with a lovely selection of poems, this reassuring book demonstrates how it is possible to direct and control the aging experience. For every person approaching retirement years, and for their friends and families, the book is an excellent resource and a practical guide. &“A highly readable, thoughtful book that contains many important facts and much wisdom.&”—Myron Weiner, M.D., University of Texas Southwestern Medical School &“A valuable addition to the existing literature, and I would recommend it to friends, patients, and their families.&”—Richard Marottoli, M.D., Dorothy Adler Geriatric Assessment Center at Yale-New Haven Hospital
Winning the Publications Game: The smart way to write your paper and get it published, Fourth Edition (Radcliffe Ser.)
by Tim AlbertThe publications game can seem tricky: knowing where to start, how to plan and draft a paper, who to pitch it to and how to present it can appear difficult enough. With the advent of e-publishing and ever-tougher regulatory frameworks surrounding research, the picture can seem even more intimidating. In this classic guide, Tim Albert demystifies the process of getting research published in his characteristically clear and engaging style. From the initial brief to final manuscript and beyond, all is explained in jargon-free, no-nonsense and encouraging terms, providing indispensable guidance to clinicians, scientists and academics in giving their research the platform it deserves.
Winning the War Against Asthma & Allergies: A Drug-Free Cure for Asthma and Allergy Sufferers
by Ellen W. CutlerAllergy types, causes, symptoms, testing and treatment. Asthma warning signs, symptoms, causes, respiratory diseases and preventative measures. Nambudripad allergy elimination technique.
Winning the War on Cancer: The Epic Journey Towards a Natural Cure
by Sylvie Beljanski&“A fascinating combination of personal story and details on the suppression of holistic cancer(and other disease) therapies&” (Ann E. Fonfa, president, The Annie Appleseed Project). President Nixon signed the National Cancer Act in 1971, declaring a war on the disease. Nearly fifty years and several billion dollars later, it looks like we have lost the battle. Or have we? What if a natural solution had been there all along, just overlooked by the pharmaceutical industry? When a new, natural, and non-toxic way to address cancer is being discovered, it is a game changer that does not go unnoticed in the scientific community. But instead of being hailed and embraced, it is fiercely opposed by prominent scientists with strong ties to the pharmaceutical industry, and the might of the government is called to the rescue. As a result, we are losing the war on cancer. Mirko Beljanski, PhD, one of the first green molecular biologists, was called upon by former French president François Mitterrand to treat his prostate cancer, allowing him to reach his second term in office, but upon his death, Beljanski became the subject of relentless persecution aimed at wiping out this information. In Winning the War on Cancer, his daughter Sylvie Beljanski outlines her journey of learning about her father&’s discoveries, and ensuring his legacy is available to all those struggling with the disease today. &“Whether a current patient or caregiver, a survivor, a researcher, an author/speaker, or a physician, the information in this book is groundbreaking, exciting, and essential to know . . . Sincere, captivating, poignant, and educational.&” —Annie Brandt, founder and president of Emerita, Best Answer for Cancer Foundation