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Thyroid Disorders with Cutaneous Manifestations
by Warren R. HeymannThe spectrum of the cutaneous manifestations of thyroid disease includes cutaneous metastases from thyroid malignancies and thryoglossal duct cysts, nonspecific alterations of the skin, hair, and nails reflecting both the hyperthyroid and hypothyroid states, and the multiple associations of thyroid disease with other cutaneous and systemic diseases. Internists, family practitioners, pediatricians, geriatricians, and dermatologists address these issues on a daily basis: When is it appropriate to evaluate a patient for thyroid disease? How should the patients be evaluated? How often should testing be performed? Should other family members be screened for thyroid disease? The purpose of The Thyroid in Dermatology is to raise awareness of the vast spectrum of thyroid-skin interactions, and to provide a framework for the appropriate diagnosis and management of these diseases.
Thyroid Eye Disease
by Raymond S. Douglas Allison N. Mccoy Shivani GuptaThis book offers ophthalmologists and medical practitioners a concise, data-driven review of the information that is most relevant in guiding the diagnosis and management of thyroid-associated eye diseases (TED). Thyroid-Associated Eye Disease can be read in its entirety to give a perspective of the field, but also considered as a reference as clinical questions arise. The goal is to deliver data- driven guidance and discreet approaches and suggestions useful for clinical practice and decision making. Advances in diagnostic evaluation, including autoantibody assessment, are reviewed, and the diagnostic features of euthyroid TED are also discussed. All relevant aspects of treatment are covered, from the use of radioactive iodine, long-term medical therapy, and surgical thyroidectomy through to the treatment of active TED by steroids and novel biologics and the role of minimally invasive surgery. Numerous supporting images are included, and helpful checklists will aid the practitioner in treatment decision making.
Thyroid FNA Cytology: Differential Diagnoses and Pitfalls
by Kennichi Kakudo Zhiyan Liu Chan Kwon Jung Mitsuyoshi Hirokawa Andrey Bychkov Chiung-Ru LaiThis is the third edition of a well-received book that recapitulates the thyroid fine-needle aspiration (FNA) cytology. It covers the basics and critical principles of thyroid cytopathology, addresses technical aspects, and presents the latest breakthrough events in the field, including the new editions of the WHO classification of thyroid tumors and the Bethesda system for reporting thyroid cytopathology.Thyroid FNA Cytology, The Third Edition is a practical handbook for cytopathologists, pathologists, cytotechnologists, endocrinologists, thyroid surgeons, radiologists, thyroid cancer patients, and their families. This edition covers more topics than the previous editions and invites authors from 20 countries from Asia, Europe, and America. It should serve as an individualized guide to readers practicing in various geographic areas with different medical settings and social resources. The book provides multiple chapters on differential diagnosis and pitfalls to show the unique approaches in many countries. The book will broaden their perspectives and serve as a foundation for further advancement in this field.
Thyroid FNA Cytology: Differential Diagnoses and Pitfalls
by Kennichi KakudoThis book offers a comprehensive guide to thyroid fine needle aspiration (FNA) cytology. Borderline/precursor tumors, which were introduced in the 4th edition of the WHO classification of thyroid tumors, are also incorporated. In this second edition, prominent international experts discuss the different approaches to thyroid FNA cytology employed in various countries such as Australia, Canada, China, Korea, Portugal, Switzerland, Taiwan, Thailand, Turkey, Ukraine, the USA, UK, Italy and Japan. The book not only covers key principles of thyroid cytopathology but also addresses technical aspects such as procedural complications, liquid-based cytology, immunocytochemistry, staining procedures, and potential pitfalls. Case-based descriptions and clinical findings, radiologic imaging, cytology, and histopathologic diagnosis – all complemented by a wealth of detailed photographs – will help reader understand and overcome many common dilemmas in daily practice. As such, the book represents an indispensable reference work for all cytopathologists, especially those practicing thyroid cytopathology.
Thyroid Fine Needle Aspiration
by Grace C. H. YangThis practical text and color atlas tells the story of 350 patients, covering a wide range of thyroid lesions with high quality composite images that correlate cytology with histology, and radiology with pathology. Each case includes clinical presentation and final pathology. Concise, easy-to-read text enables readers to quickly find the information they need for accurate diagnosis. 'Lookalike' lesions are grouped together so the subtle cytological differences can be appreciated. The author's practical approach explains mistakes made and lessons learned, so diagnostic pitfalls can be avoided. Logarithmic triage diagrams are provided, as well as over 2000 printed photomicrographs and a CD-ROM offering images in downloadable format. Written by a leading cytopathologist who has performed onsite assessment for over 10,000 ultrasound-guided thyroid fine needle aspirations, this is an important resource for all healthcare professionals dealing with thyroid patients, including cytopathologists, surgical pathologists, cytotechnologists, sonographers, radiologists, endocrinologists and surgeons.
Thyroid For Dummies
by Alan L. RubinIf you or a loved one has been diagnosed with a thyroid condition, you’ve probably found out at least a little about this mysterious gland—just enough to want to look for answers to the many questions that keep popping up in your mind. What causes this condition? How is it treated? What can you do to get healthy again? Thyroid for Dummies, 2nd Edition gives you the detailed information you're looking for on new methods for detecting thyroid disease in both adults and children, alternative treatments, pros and cons of powerful new drugs now on the market, advice for managing the disease through changes in exercise and diet, and much more. You're discover: What the thyroid does How to identify a sick thyroid and recognize who's at risk Ways to find the right thyroid doctor How to cope with hypothyroidism in children The hereditary connection to thyroid disease How thyroid disease affects the elderly The effects of hyperthyroidism during pregnancy How to decide if surgery is necessary Ten myths about thyroid health Updated to address advances made since the first edition, including the latest thinking on understanding thyroid disease's connection to depression and mania, Thyroid for Dummies, 2nd Edition will tell you everything you need to know about how the thyroid functions, what makes it malfunction, and what to do when a problem occurs.
Thyroid Function Testing
by Gregory A. BrentThyroid function tests are performed by essentially all medical practitioners across every clinical setting. Significant insights have been gained into thyroid regulation and thyroid hormone metabolism that influence the selection and interpretation of thyroid function tests. The first section of the book presents the recent advances in thyroid physiology and a discussion of genetic influences on thyroid function tests. The population variation in the TSH "set point", now thought to be genetically determined, influences the evaluation of thyroid function and thyroid function "targets" for treatment of thyroid disease. The basics of thyroid function measurements, approaches, limitations, and clinical applications will be described for the major categories of thyroid function tests. Application of thyroid function testing to the key clinical settings are discussed, including in the management of thyroid diseases. The influences of drugs on thyroid function testing remains a major clinical issue and is covered in a separate chapter and the issue of thyroid function test screening is also discussed. The authors represent leaders in research and thyroid clinical practice as well as representing a variety of outstanding institutions. This volume provides material that is clinically practical and informed by the most recent scientific advances.
Thyroid Hormone Disruption and Neurodevelopment (Contemporary Clinical Neuroscience)
by Noriyuki Koibuchi Paul M. YenThyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans. However, the molecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under various pathological conditions. In addition, environmental factors including endocrine-disrupting chemicals and bacterial endotoxins may disrupt thyroid hormone action in brain, causing abnormal brain development and functional disruption. This is a first book to comprehensively describe the effect of thyroid hormone disruption in the central nervous system. The first section deals with the disruption of thyroid hormone action at the molecular level. First the authors provide a summary of the possible molecular mechanisms of thyroid hormone action in the brain, then they discuss several factors that may disrupt thyroid hormone action. In the second section, animal models to study thyroid hormone action will be introduced. An interesting character of thyroid hormone deficiency is that, without thyroid hormone, the thyroid hormone receptor may act as a “repressor” of gene expression, causing more severe consequence than those of thyroid hormone receptor knockout animals. Thus, several different kind of animal models may be used to clarify the role of thyroid hormone and its receptor in the brain. In the third section, human studies on thyroid disease and neurodevelopment will be introduced. Although endemic cretinism induced by iodine deficiency and sporadic cretinism by various thyroid mutation are well known, the pathophysiological mechanisms that create each abnormal phenotype are not fully understood.
Thyroid Hormone Receptors
by Aria BaniahmadA panel of outstanding investigators surveys and explains the major cutting-edge methods used in thryroid receptor (TR) research and explains their practical experimental details. Described in step-by-step detail to ensure robust experimental results, the techniques presented cover a wide variety of key areas, including TR in development and knockout (mouse and Xenopus), transcriptional regulation by TRs in both cell-free systems and in living cells, and TR mutant analysis of patients. Additional methods provide powerful tools for the isolation of TR-regulated protein complexes, for studying the oncogene v-Erba in blood cell differentiation, and for target gene analysis in the brain. Microarray chip methods are also presented for analyzing the organs of transgenic mice to identify target genes in the liver.
Thyroid Hormones: Methods and Protocols (Methods in Molecular Biology #2876)
by Constanza Contreras-JuradoThis volume focuses on thyroid hormones and their transporters and receptors. Chapters focus on a wide range of methods and protocols that are important for advancing the elucidation of the role of thyroid hormones in our body. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Thyroid Hormones: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
Thyroid Power: 10 Steps to Total Health
by Richard L. Shames Karilee Halo ShamesFatigue; weight gain; depression; arthritis; high cholestrol; low sex drive; skin, digestive, and female problems; abnormal blood pressure -- all may be symptoms of low thyroid, one of the most misdiagnosed disorders in America. Thyroid Power can help you determine whether you're one of the millions who suffer from low thyroid. It discusses food, vitamins, and natural remedies that support thyroid health;explains how to avoid environmental and emotional triggers; and offers tips from thyroid support groups. By following this clear 10-step program and working with your health practitioner, you can channel the incredible power of your thyroid into greater health and well-being.
Thyroid Radiofrequency Ablation: A Comprehensive Guide
by Auh Whan Park Giovanni Mauri Ji-Hoon KimThis comprehensive book is the definitive guide to thyroid radiofrequency ablation (RFA). Thyroid nodules, whether benign or malignant, are prevalent, and while benign nodules often don't require treatment, some patients may seek intervention due to functional abnormalities or mass effects. Traditional treatments like surgery and radioactive iodine therapy are effective but may not be suitable for all patients due to risks or personal preferences. Thermal ablation, including radiofrequency, microwave, and high-intensity focused ultrasound, offers a promising non-surgical alternative. Among these, radiofrequency ablation (RFA) stands out as the most extensively researched and proven therapy, boasting both safety and clinical efficacy. This book represents a pivotal resource in steering thyroid patients toward non-surgical treatments, a paradigm shift in thyroid care. Starting with a comprehensive overview of thyroid nodule diagnosis and management, the book delves into specific guidance on thyroid RFA. Chapters explore the procedure itself, advanced techniques, clinical efficacy, and long-term management strategies. Additionally, it covers related techniques like embolization and RFA's applications in thyroid cancer. This book serves as an indispensable guide for managing patients with thyroid nodules. Whether you're seeking foundational knowledge or advanced insights, this book equips you with the expertise needed to navigate the complexities of thyroid RFA and deliver optimal patient care.
Thyroid Surgery
by David J. Terris Melanie W. Seybt Paolo Miccoli Michele N. MinutoThis highly practical, full color teaching tool is focused on best surgical practice in thyroid surgery, including the key issue of prevention and management of surgical complications. An accompanying website contains twenty step-by-step surgical videos of thyroid surgery in action. Several chapters are included on brand new surgical techniques, such as robotic and image-localized surgery.
Thyroid Surgery (Updates in Surgery)
by Mario Testini Angela GurradoThis open access book on thyroid surgery has been authored by an international team of contributors who present a comprehensive understanding of both benign and malignant thyroid disorders. It also outlines an interdisciplinary approach to their surgical management that reflects the latest changes in surgical techniques. The book reviews the most up-to-date literature available on thyroid surgery and presents it in a concise manner for use in clinical practice. For each thyroid disorder, the book covers etiology, clinical manifestations, diagnostic and localization procedures, as well as surgical and non-surgical treatment options. The operating techniques and postoperative management are explained in detail, while the benefits, risks, controversial issues, and cost-effectiveness of each approach are reviewed. To aid in the understanding of complex information, the book features drawings and photographs. Written in an easy-to-understand style, the book includes tables and diagrams that highlight best practices and current guidelines, as well as self-assessment material at the end of each section. It serves as an ideal resource for all levels of surgical experience, from a practical reference for endocrine surgeons to a perfect companion for students and residents.
Thyroid Surgery: Principles and Practice
by Madan Laxman KapreThis book will bridge a gap between the huge platform of literature available about thyroid surgery and the practical working reality. The pearls in techniques and surgical procedures will be exhaustively detailed with authors' individual experience enriched with quality photographs. It covers management of large/massive multinodular goiters which are the hall mark of Indian Thyroids. However, the emphasis will be more on applying this knowledge to a given patient and would largely revolve around this theme. It aims to provide a take home message in controversial areas and is a ready reference to all interested in learning science and craftsmanship of thyroid surgery. Key Features Covers all topics comprehensively with a practical approach Inclusion of guidelines adds value to the content Discusses all investigatory modalities Consists of useful surgical tips with exhaustive operating photography Features large anatomical illustrations with cadaveric dissections
Thyroid Systems Engineering: A Primer in Mathematical Modeling of the Hypothalamus-Pituitary-Thyroid Axis
by Simon Goede Melvin Khee-Shing LeowIn recent years, a considerable amount of effort has been devoted, both in industry and academia, towards the behavioral modeling, evaluation and prediction of the hypothalamus pituitary thyroid system.Thyroid Systems Engineering targets an optimal treatment of people suffering from thyroid hormone disorders. The content is motivated by in-depth observations of such patients whose rich data supported the theoretical framework arising from formal mathematical reasoning, guided by the nature of thyroid physiology. Leveraging on the insights emerging from the unique combination of an electrical engineer working with a clinical thyroidologist, and both being scientists skilled in mathematics, the authors introduce this new discipline and field of scientific investigation aptly designated as Thyroid Systems Engineering.Readers will discover that mathematics can indeed model the behavior of the hypothalamus-pituitary-thyroid (HPT) axis. Focused on modeling, each of the eighteen chapters gives the reader a notion of the application of relevant mathematics to pertinent issues encountered in mainstream thyroidology. Many cellular processes resemble the flux of variables and states in a complex multi-parameter space through time analogous to current flow in electrical networks. It is then logical to apply the principles and physical laws of electrodynamics, electrical network theory, control systems theory and signal theory to many of the biological phenomena encountered in endocrinology. Such an approach is used liberally throughout the book and successfully yields elegant solutions to a number of models presented within.This book can serve as a reference to mathematical modeling in other aspects of endocrine physiology, and as the starting point for a fundamental course in medical modeling. It will appeal to postgraduates in electrical engineering, academic physicians and biomedical researchers. Further, readers equipped with advanced calculus, electrical network theory, control theory and signal theory should be able to follow the mathematical expositions that describe thyrotropic control. They represent a new discipline based on mathematical modeling in physiology applicable to medical diagnostics, measurement and treatment to cooperate in the clinical team and realize an optimized treatment for patients.
Thyroid Ultrasound and Ultrasound-Guided FNA
by Robert A. Levine H. Jack Baskin Sr. Daniel S. DuickSince the first publication of Thyroid Ultrasound and UGFNA in 2000, ultrasound has become established as a primary tool for diagnosing and managing thyroid disease. Indeed, over the last 10 years ultrasound has become a catalyst for bringing together endocrinologists, surgeons, radiologists, and pathologists to create a multidisciplinary approach to the management of thyroid disease which is and will continue to benefit our patients.
Thyroid Ultrasound: From Simple to Complex
by Alexander N. Sencha Yury N. PatrunovThis book is a wide-ranging and up-to-date guide to the use of ultrasound for imaging of the thyroid that will meet the needs of novices while providing more experienced professionals with advanced information. All of the techniques employed in modern thyroid ultrasound are covered, from conventional grayscale and Doppler imaging to elastography and contrast-enhanced ultrasound, with a focus on practical aspects and with detailed analysis of their diagnostic value and limitations. The characteristic ultrasound findings of the normal thyroid and a wide range of thyroid diseases and disorders are described with the aid of hundreds of high-quality images. Diffuse changes and thyroid lesions are discussed in depth, paying close attention to aspects of importance for early detection and differential diagnosis. In this context the authors summarize their personal experiences in the use of qualitative parameters of compression elastography and quantitative data of shear-wave elastography. In addition, a practical approach to the risk stratification of thyroid nodules is proposed. The book concludes with a resumé of the main challenges and pitfalls in thyroid ultrasound.
Thyroid and Heart: A Comprehensive Translational Essay
by Alessandro Pingitore Giorgio Iervasi A. Martin Gerdes Salman RazviIn recent years, several scientific papers have highlighted the role of the thyroid system in cardioprotection, and several clinical studies – including multicenter studies – have identified the role of thyroid hormones (TH) in the development and progression of cardiovascular disease, making an update of TH and heart relationship both necessary and timely. This second edition of Thyroid and Heart failure provides a careful and updated review of the experimental, clinical and epidemiological results in the field of TH and heart failure, with a particular focus on the translational - bench to bedside - significance of the obtained results. It discusses topics such as the molecular, structural, functional, cellular and histological cardiac changes; the reversibility of these changes with TH replacement therapy; the systemic effects – kidney, hormonal pathways systems, brain, muscle, etc – of altered TH metabolism in HF, as well as the clinical and prognostic implications. The section devoted to the potential therapeutic treatments has been expanded. Thanks to its translational approach to this highly complex subject, the book will be of interest to a broad readership, including cardiologists, endocrinologists and internists.
Thyroid and Parathyroid Diseases: A Case-Based Guide
by Tamer Özülker Mine Adaş Semra GünayThis book presents as teaching files a collection of cases of thyroid and parathyroid diseases seen at various high-volume endocrinology centers. The cases, most of which are accompanied by instructive images, have been selected in order to impart clinically relevant knowledge on the full range of endocrine disorders of thyroid and parathyroid origin. Accordingly, the book covers not only situations that are frequently encountered by the clinician in primary care, but also uncommon disorders and unusual presentations of common disorders. The comprehensive nature of the coverage will assist in resolving diagnostic dilemmas, and the reader will also find up-to-date information on disease management. The recommendations provided are based on current evidence-based clinical practice guidelines and are supported by relevant literature so as to harmonize available evidence-based protocols with current clinical practice. Thyroid and Parathyroid Diseases: A Case-Based Guide is designed to be thought provoking and to aid knowledge retention. Written by renowned experts in nuclear medicine, clinical endocrinology, oncology, and general surgery, it will appeal to specialists and residents in these fields.
Thyroid and Parathyroid Disorders in Children: A Practical Handbook
by Pallavi Iyer and Herbert ChenThyroid and Parathyroid Disorders in Children: A Practical Handbook offers a focused and practical approach to diagnostic and therapeutic (both medical and surgical) interventions in management of thyroid and parathyroid diseases in children. It is divided into two sections: thyroid and parathyroid, with each section discussing the use of the laboratory testing and radiographic modalities in the study of these glands. This guides the reader to know the utility and limitations of the findings when approaching a child with these conditions. Written by international experts in the fields of pediatric endocrinology and endocrine surgery, it is ideal for trainees, practicing physicians and professionals who care for children with endocrine conditions. Key Features Discusses differences in recognition and management of thyroid and parathyroid disorders in children compared with adults, with both common and rare disorders described along with their medical and surgical treatment techniques. Aids the practicing physicians, endocrinologists, trainees, and fellows in understanding the complex concepts in a practical way. Fills the gap in the market for a much-needed book concentrated on endocrine neck diseases of childhood.
Thyroid and Parathyroid Ultrasound and Ultrasound-Guided FNA
by Robert A. Levine Daniel S. Duick Mark A. LupoIn this concise, gold-standard 4th edition book, the volume editors and authors synthesize the prior three editions and provide a comprehensive and expanded review on the latest in the diagnosis and management of thyroid nodules, as well as an update on parathyroid disease and non-endocrine lesions of the neck. This user-friendly edition again emphasizes a multidisciplinary approach to thyroid ultrasound and UGFNA, offering all the new information and subtleties clinicians must know in the application of this technique, now firmly established as a primary tool for diagnosing and managing thyroid disease. Developed by renowned experts in thyroid and parathyroid disease, the book covers not only thyroid and parathyroid disease, but also imaging of the salivary glands and other non-endocrine lesions of the neck. In this edition, the authors expand the chapters on both surgical and non-surgical management. Given the increased use of molecular markers in thyroid evaluation, an excellent chapter addresses this topic. Finally, as more endocrinologists and surgeons perform ultrasounds in their office practices, a chapter on authoring ultrasound reports is now included. Combining the collective wisdom of specialists who treat patients with thyroid nodules, thyroid cancer and parathyroid disease, Handbook of Thyroid and Parathyroid Ultrasound and Ultrasound-Guided FNA, 4th Edition is an invaluable resource and will continue serving as the "go to" guide for surgeons, endocrinologists, fellows and residents. Foreword by Peter A. Singer, MD, Chief of Clinical Endocrinology and Director, Thyroid Diagnostic Center, Keck School of Medicine of USC, Los Angeles, CA.
Thyroid, Obesity and Metabolism: Exploring Links Between Thyroid Function, Obesity, Metabolism and Lifestyle
by Livio LuziThis book will provide readers with up-to-date information on thyroid diseases, obesity and metabolic syndrome. The innovative element is the presentation and exploration of possible connections linking thyroid diseases and metabolism dysfunction. Starting from the classification and diagnosis of thyroid diseases, obesity and metabolic syndrome, techniques to study and treat each of the mentioned diseases are given in an easy-to-use way.This volume will be a useful tool for endocrinologists, diabetologists, dieticians, and any professionals involved in the treatment of thyroid diseases.
Thyroid: How to prevent, take care of oneself, and stay healthy
by Daniela PaceThis book is a journey around the vast subject of the thyroid, designed to share information about its functioning and the pathologies that can affect it. It is intended to provide accessible and simplified language, distancing itself from technicalities of the medical profession.It represents an itinerary that invites step-by-step learning and taking care of one's own health through prevention and the adoption of healthy lifestyle habits. Reading it helps improve visual memory and facilitates the acquisition of concepts, shortening the distances for both the reader and the specialist. The medical-scientific information maintained in this book maintains its authoritative nature while promoting sharing.This book is for everyone: young, adults, and the elderly. It is for you, for your well-being and the well-being of your loved ones.
Tibetan Medicine in the Contemporary World: Global Politics of Medical Knowledge and Practice (Needham Research Institute Series)
by Laurent PordiéThe popularity of Tibetan medicine plays a central role in the international market for alternative medicine and has been increasing and extending far beyond its original cultural area becoming a global phenomenon. This book analyses Tibetan medicine in the 21st century by considering the contemporary reasons that have led to its diversity and by bringing out the common orientations of this medical system. Using case studies that examine of the social, political and identity dynamics of Tibetan medicine in Nepal, India, the PRC, Mongolia, the UK and the US, the contributors to this book answer the following three, fundamental questions: What are the modalities and issues involved in the social and therapeutic transformations of Tibetan medicine? How are national policies and health reforms connected to the processes of contemporary redefinition of this medicine? How does Tibetan medicine fit into the present, globalized context of the medical world? Written by experts in the field from the US, France, Canada, China and the UK this book will be invaluable to students and scholars interested in contemporary medicine, Tibetan studies, health studies and the anthropology of Asia. 'Winner of the ICAS Colleagues Choice Award 2009"