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Toxins and Targets
by David Maguire Dianne Watters John Pearn Martin LavinFirst Published in 1992. The last decade of the twentieth century has seen an unprecedented advocacy for the preservation of a safe environment, and the prevention of ill-health from toxic chemicals. Human activity, however, is responsible for introducing new toxins into the environment. In order to control competitors for human food sources, an armament of pesticides has been assembled and their widespread and largely uncontrolled application has been permitted. It is only when the health of the population begins to suffer from the effects of these chemicals that the efficacy of their use is questioned. Decision-makers whose roles involve the promotion and control of the environment must look to lessons that can be learnt from biosystems that include animals other than man. Toxins and Targets details the way in which organisms from diverse habitats in the plant and animal kingdoms have adapted to handle toxins safely. Part I, on the aquatic environment, highlights the means by which marine organisms have adapted their toxins to be effective in a world of high aqueous solubility and infinite dilution. Part II deals with venomous terrestrial organisms and the mechanisms by which they damage animal cells, and Part III considers the way in which human society attempts to investigate toxicity and to control both synthetic and naturally occurring poisons. The development of a safe environment depends on increased knowledge and novel approaches to solving escalating problems. This book is a step towards this end.
Toxins in Food
by Waldemar M. Dąbrowski Zdzisław E. SikorskiWhile systems such as GMP and HACCP assure a high standard of food quality, foodborne poisonings still pose a serious hazard to the consumer's health. The lack of knowledge among some producers and consumers regarding the risks and benefits related to food makes it imperative to provide updated information in order to improve food safety.To
Toxisch
by Rainer Biesinger Max KluteDurch den Konsum von Rauschdrogen ballern sich tagtäglich Millionen von Menschen aus ihrer subjektiv gefühlten Realität heraus. Angefangen bei Alkohol und Nikotin haben wir es heute mit einem verantwortungslosen, unkultivierten und gefährlichen Konsumverhalten zu tun. Dieses Buch stellt die durchaus erlaubte und provokative Frage, ob die derzeitige Drogenpolitik noch „up to date“ ist, bzw. wo sie durch ihre restriktive Herangehensweise nicht völlig versagt hat!? Wo liegen die Ursachen dieses Konsumverhaltens und wie ist es um einen liberalisierten und aufgeklärten Umgang mit gewissen Substanzen bestimmt? Mit diesem mutigen und investigativen Werk nehmen die beiden Autoren eine authentische Perspektive zum Thema Rauschdrogen in Deutschland ein. Und sie wissen, wovon sie reden! Ein Buch für User, Neugierige, Eltern, Pädagogen, Therapeuten, Ärzte, Sozialarbeiter, Interessierte der Drogenverbotsdebatte und alle, denen etwas daran liegt, dass die Gesellschaft in Sachen Suchtprävention und Selbstbestimmungsrecht von Konsumenten endlich wach wird und handelt.Inklusive Videointerviews mit den Autoren und Geleitworte von Kriminalbiologe Dr. Mark Benecke, Jugendrichter Andreas Müller und dem Grimme-Preisträger $ick.
Toxoplasma gondii: Methods and Protocols (Methods in Molecular Biology #2071)
by Christopher J. TonkinThis volume covers a diverse collection of protocols currently being used by the Toxoplasma research community, and also looks at innovative methods that are pushing the boundaries of possibilities. Chapters in this book discuss topics such as isolation and genotyping of Toxoplasma gondii strains; assessing rhoptry secretion in T. gondii; plate-based quantification of stimulated Toxoplasma egress; methods to study ocular toxoplasmosis; and metabolic analysis of Toxoplasma gondii tachyzoites. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, Toxoplasma gondii: Methods and Protocols is a valuable resource for students or groups starting off in the field, as well as laboratories interested in implementing the latest techniques described in the book.
Toxoplasmosis of Animals and Humans
by J. P. DubeyThis is the only book to cover toxoplasmosis of animals and humans thoroughly in one single source. Found worldwide from Alaska to Australasia, Toxoplasma gondii is the cause of one of the most common parasitic infections in humans, livestock, companion animals, and wildlife, and is included on the list of potential bioterrorism microbes. Furthermore, T. gondii has been and continues to be used extensively as a model for the cell biology of apicomplexan parasites. In the decade since the second edition of this book was published, there has been an explosion of knowledge concerning the parasite Toxoplasma gondii and toxoplasmosis. This update provides unique information on all known host types for this parasite, with an additional chapter on history, substantial updates throughout, and a detailed focus on the biology of the parasite in Chapter 2. The third edition is compiled by author JP Dubey, an authority on T. gondii who has worked with virtually all hosts of the protozoan during the last 55 years, including humans, all livestock species, wildlife, and zoo animals. The book distills the voluminous and potentially confusing scientific literature, that has grown geometrically in the 30+ years since the publication of the first edition, into a comprehensive resource for all professionals, graduate students and researchers working in this field.
Toyota Production System: Beyond Large-Scale Production
by Taiichi OhnoIn this classic text, Taiichi Ohno--inventor of the Toyota Production System and Lean manufacturing--shares the genius that sets him apart as one of the most disciplined and creative thinkers of our time. Combining his candid insights with a rigorous analysis of Toyota's attempts at Lean production, Ohno's book explains how Lean principles can improve any production endeavor. A historical and philosophical description of just-in-time and Lean manufacturing, this work is a must read for all students of human progress. On a more practical level, it continues to provide inspiration and instruction for those seeking to improve efficiency through the elimination of waste.
Trace (Kay Scarpetta #13)
by Patricia CornwellThe thirteenth book in the Kay Scarpetta series, from No. 1 bestselling author Patricia Cornwell. 'America's most chilling writer of crime fiction' The TimesAgainst her own judgement and the advice of Benton Wesley and her niece, Lucy, Scarpetta agrees to return to Virginia as a consultant pathologist on a case involving the death of a fourteen-year-old girl. Accompanied by Pete Marino she finds the once familiar territory of her morgue and her department much changed, and the new Chief Medical Examiner treats her with disdain despite the obvious fact that he is in desperate need of her expertise. But professional as ever, she re-examines the evidence and proves the girl was murdered. She also finds trace evidence which matches that found on an accident victim and at the scene where one of Lucy's operatives was attacked. It is not only a forensic puzzle, but opens up the probability that someone is after those closest to Scarpetta. Praise for the groundbreaking series: 'One of the best crime writers writing today' Guardian 'Devilishly clever' Sunday Times 'The top gun in this field' Daily Telegraph 'Forget the pretenders. Cornwell reigns' Mirror 'The Agatha Christie of the DNA age' Express
Trace (Kay Scarpetta)
by Patricia CornwellThe thirteenth book in the Kay Scarpetta series, from No. 1 bestselling author Patricia Cornwell. 'America's most chilling writer of crime fiction' The TimesAgainst her own judgement and the advice of Benton Wesley and her niece, Lucy, Scarpetta agrees to return to Virginia as a consultant pathologist on a case involving the death of a fourteen-year-old girl. Accompanied by Pete Marino she finds the once familiar territory of her morgue and her department much changed, and the new Chief Medical Examiner treats her with disdain despite the obvious fact that he is in desperate need of her expertise. But professional as ever, she re-examines the evidence and proves the girl was murdered. She also finds trace evidence which matches that found on an accident victim and at the scene where one of Lucy's operatives was attacked. It is not only a forensic puzzle, but opens up the probability that someone is after those closest to Scarpetta. Praise for the groundbreaking series: 'One of the best crime writers writing today' Guardian 'Devilishly clever' Sunday Times 'The top gun in this field' Daily Telegraph 'Forget the pretenders. Cornwell reigns' Mirror 'The Agatha Christie of the DNA age' Express
Trace Elements and Minerals in Health and Longevity (Healthy Ageing and Longevity #8)
by Marco Malavolta Eugenio MocchegianiThis book describes the role of trace elements in health and longevity, pursuing a biogerontological approach. It offers essential information on the impact of trace elements on molecular and physiological processes of aging, and on their impact on health in connection with aging. The major topics covered in its 11 chapters, each dedicated to a specific trace element or mineral, are: a) Role of the element in species longevity, b) Recommended intake for longevity in animal species and in the elderly, c) Deficiency and age-related disease, d) Excess/toxicity and age-related disease, ande) Interactions with drugs prescribed in the elderly. Clinical, animal and other laboratory models of interest in aging are included, which enable a more in-depth analysis to be made. The respective chapters are a mixture of overviews and more in-depth reviews in which the mechanisms of aging are described from the point of view of their specific interactions with trace elements and minerals.
Trace Elements in Brain Health and Diseases (Nutritional Neurosciences)
by Wael Mohamed Rajat SandhirThis book reviews the role of trace elements in brain development, function, metabolism, and neurodegenerative disorders. It explores the molecular mechanisms of the effects of trace elements on metabolic pathways, mitochondrial nutrients, neurodegeneration, Central Nervous System (CNS) disorders, cell signaling, and neuronal functions. The book also discusses transport mechanisms of trace elements within CNS and their impact on neurotransmitter biology. Further, it examines the deleterious effects due to dyshomeostasis of trace elements in the central nervous system (CNS), resulting in damage to neurons and glial cells through the generation of reactive oxygen species and oxidative stress turn leading to neurodegeneration and neurological dysfunction. The book also explores the putative role of trace element deficiency in psychiatric disorders, including depression, and the imbalance of trace elements on neuronal genomic stability.
Trace Elements in Laboratory Rodents (Methods In Nutritional Research Ser.)
by Ronald Ross WatsonWritten by the international community's leading experts, Trace Elements in Laboratory Rodents describes the best and most current methods to provide deficient or supplemental trace elements to laboratory animals, as well as how to assay them. The experts warn of the common pitfalls and hidden problems in nutritional testing and how to avoid them. This how-to approach focuses on the technical details that make good, reliable studies. Common as well as rare or recently recognized minerals are described relating to both dietary supplementation and measurement in tissues.If you are a researcher, professor, or student working in nutrition, food science, biochemistry, or veterinary medicine, you can't afford to be without this excellent hands-on methods manual!
Trace Evidence
by Elizabeth BeckaA forensic thriller that unlocks criminal secrets...and criminal science. In the bestselling tradition of Patricia Cornwell and Kathy Reichs, comes a riveting forensic thriller by a dazzling new talent in crime fiction. This authentic, high-octane debut is inspired by Elizabeth Becka's own career and her experience using physical evidence recovered from crime scenes to unlock the secrets of the dead and bring justice to those who have no voice. "The combination of a credible, likeable hero, and a bizarre, chilling story is rare in crime fiction, but in Trace Evidence Elizabeth Becka makes the tumblers click perfectly
Trace Metals Selenium, Chromium and Vanadium Chemistry, Biology & Human Health: Chemistry, Biology and Human Health
by Bimal Krishna Banik Sangeeta Bajpai Monika Kamboj Garima PandeyTrace elements selenium, vanadium and chromium play an essential role in the nutrition of both animals and humans. Their accumulation in various environments and the subsequent transition of these elements into the food chain significantly affect human and environmental health. This volume emphasizes the integrative aspects of selenium, vanadium and chromium with chapters dedicated to their fundamental chemistry, biochemistry, clinical science and environmental effects. Each chapter focuses on the advancement of scientific knowledge about these trace elements. Important studies on these elements will be described through interdisciplinary approaches. Emphasizes chemistry, biology, and toxicology of trace elements Se, V & Cr helping readers to understand their cycle in environment and effects on humans. Focuses on three important trace minerals and their recent research involving improvement of human health. Timely presentation of research being conducted on the roles of Se, V, Cr in health and disease.Addresses usefulness of trace metals in food science & nutrition, unlike other books. Distinctively presents extensive and integrative information of the fundamental aspects of Selenium, Vanadium, and Chromium in an easy to read format.
Trace Metals and Fluoride in Bones and Teeth
by Nicholas D. Priest Frank Van de VyverThis volume is a comprehensive introduction to the analysis, binding, uptake, metabolism, kinetics, modeling, distribution, occurrence, toxicity and chelation of metals and fluoride in the body, with special reference to mineralized tissues. Both toxic and relatively harmless polyvalent cations and anions are considered. Included are some which are stable, and others which are radioactive. While a number are essential trace elements, others have no known metabolic role. Most chapters are concerned with the uptake of bone-seeking ions by the living skeleton, but aspects of the post-mortem uptake of metals and the process of fossilization are also considered. Highlighted are the utility of modern analytical techniques and the more important bone-seeking elements including aluminum, lead, cadmium, fluorine and the radioactive heavy metals including uranium and plutonium. This important publication is of particular value to those in the fields of biochemistry, radioactive waste, geology, physiology, dentistry, orthopedics, radiology and nuclear medicine, urology, industrial hygiene, pharmacology, anthropology, paleontology, and archeology.
Traces of Mercury
by Clark HowardA small-town doctor copes with an escalating medical mystery in this thriller by a &“superlative storyteller&” (Publishers Weekly).Lee Madrigal became a doctor in spite of his difficult working-class upbringing, with a mother who died young and a father who fell under the spell of alcohol. Now Lee serves his neighbors in the California community where he grew up, and has reunited with his high school sweetheart. But the medical cases he&’s been handling lately have been bothering him: a baby born with inexplicable birth defects; a young man with symptoms that seem to mimic a venereal disease but whose blood tests come back clean. As the mystery mounts, Lee will discover a terrible secret about his hometown, and a battle to save lives will ensue . . .
Tracheostomy
by Terence Pires de FariasDespite often taken as a simple procedure, techniques on tracheostomy have evolved considerably on the last few years. Consequently, new technical variations and indications for different purposes are being developed and proposed. The current book is proposed to serve as a comprehensive guide exclusively devoted to tracheostomy, discussing its most important details, variations and indications. Here the reader will find a broad discussion ranging from the most basic pre-clinical aspects to post-surgical procedures and complications. Great emphasis is placed on key topics such as the oncologic patient, variations of the technique, and tracheostomy in the intensive care unit, among others. Additionally, some issues that are not commonly discussed in regular textbooks, like tracheostomy in child and in great obese, are also included. With a wealth of photos, illustrations and tables, Tracheostomy – A Surgical Guide provides the material necessary to support a safe and effective surgical intervention in different populations and surgical contexts, with the hope that it will result in improved care for patients who underwent tracheostomy.
Tracheotomy Management
by David Goldenberg Elizabeth H. Sinz Peggy A. SeidmanPatients with tracheotomies are managed by a wide variety of healthcare professionals. As a result, information regarding best practice is scattered throughout the medical literature and can be difficult to identify and implement in the clinical setting. Tracheotomy Management: A Multidisciplinary Approach is a practical review of all tracheotomy procedures and acute and chronic tracheotomy care. It combines evidence-based practice and expert opinion to create an invaluable hands-on guide for any healthcare provider managing patients with tracheotomies. Each chapter is authored by at least two different subspecialists, contains case studies with real-life examples of problematic clinical scenarios, and is enhanced by high quality colour images and algorithms. The rationale for different approaches is discussed to guide the decision-making process. Written and edited by tracheotomy experts from a wide variety of disciplines, Tracheotomy Management: A Multidisciplinary Approach is essential reading for anesthesiologists, nurse anesthetists and critical care and emergency physicians.
Tracheotomy and Airway: A Practical Guide
by Eckart Klemm Andreas NowakIn dem Kompendium wird die sachgerechte Durchführung aller Varianten der Tracheotomie beschrieben. Im Mittelpunkt der interdisziplinären Darstellung stehen insbesondere die Analyse schwerer Früh- und Spätkomplikationen, ihre Vermeidung und ihre Therapie. Auch die logopädische Behandlung sowie neue Aspekte des Airway-Managements werden berücksichtigt.
Track and Trace Management System for Dementia and Intellectual Disabilities (Advanced Technologies and Societal Change)
by Amit Kumar George Ghinea Suresh MeruguThis book reviews humanitarian literature and presents the development of low-cost track & trace management system integrated with accurate GPS location data pinging using Internet of Things (IoT). The first part relates to mobile device configuration with an embedded GPS and wireless Internet connection to transmit its current location. The second part presents web server implementation and development that receives the data, parses it, and stores it for access over the Internet. The third part discusses the user interface that allows one to visually identify the current location of the device.
Tracking Radiation Exposure from Medical Diagnostic Procedures
by National Research Council Division on Earth and Life Studies Nuclear and Radiation Studies Board Committee on Tracking Radiation Doses from Medical Diagnostic ProceduresThe growing use of medical diagnostic procedures is correlated with tremendous and undeniable benefits in the care of most patients. However, it is accompanied by growing concerns about the risks associated with diagnostic computed tomography and other procedures that utilize ionizing radiation. A number of initiatives in radiation safety in medicine have taken place in the United States and internationally, each serving different purposes. Their ultimate goals are to provide higher quality clinical management of the patient and to ensure that reasonable steps are taken to keep the exposures as low as possible without compromising diagnostic efficacy. Tracking Radiation Exposure from Medical Diagnostic Procedures: Workshop Reports provides a summary of the presentations and discussions that took place during the December 8-9, 2011, workshop titled "Tracking Radiation Exposure from Medical Diagnostic Procedures." This workshop was organized by the Nuclear and Radiation Studies Board of the National Academy of Sciences and sponsored by the Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, and the U.S. Department of Health and Human Services. This workshop report was authored by a six-member committee of experts appointed by the National Academy of Sciences. This committee brought together public health regulators, physicians, manufacturers, researchers, and patients to explore "why," "what," and "how" to track exposure from medical diagnostic procedures and possible next steps.
Tracking and Preventing Diseases with Artificial Intelligence (Intelligent Systems Reference Library #206)
by Jerry Chun-Wei Lin Philippe Fournier-Viger Mayuri Mehta Maulika PatelThis book presents an overview of how machine learning and data mining techniques are used for tracking and preventing diseases. It covers several aspects such as stress level identification of a person from his/her speech, automatic diagnosis of disease from X-ray images, intelligent diagnosis of Glaucoma from clinical eye examination data, prediction of protein-coding genes from big genome data, disease detection through microscopic analysis of blood cells, information retrieval from electronic medical record using named entity recognition approaches, and prediction of drug-target interactions.The book is suitable for computer scientists having a bachelor degree in computer science. The book is an ideal resource as a reference book for teaching a graduate course on AI for Medicine or AI for Health care. Researchers working in the multidisciplinary areas use this book to discover the current developments. Besides its use in academia, this book provides enough details about the state-of-the-art algorithms addressing various biomedical domains, so that it could be used by industry practitioners who want to implement AI techniques to analyze the diseases. Medical institutions use this book as reference material and give tutorials to medical experts on how the advanced AI and ML techniques contribute to the diagnosis and prediction of the diseases.
Tractus Immuno-Logicus: A Brief History of the Immune System
by Antonio A. de FreitasThe history of this text started years ago after reading Wittgenstein'sTratactus Logico-Philosophicus. At some time later, it seemed to me a good idea to follow thetratactus structure to attempt to write a minimal description of the immune system. I finally did it for fun and hopefully to be useful to whomever reads it.The text reflects my ow
Trade Agreements and Public Health: A Primer for Health Policy Makers, Researchers and Advocates (Palgrave Studies in Public Health Policy Research)
by Ronald Labonté Deborah GleesonThe need for policy coherence between trade and health has never been greater, yet few public health workers are equipped to navigate this complex field. This book aims to fill this gap, providing a focused and readable introduction to the topic. It introduces the principles underpinning trade treaties and examines the implications of trade rules for health services and access to medicines, unhealthy commodities, labour rights and the environment. It explores the trade policy making process, methods for trade and health research, and recommendations for strengthening policy coherence.
Trade Therapy: Deepening Cooperation to Strengthen Pandemic Defenses
by World Bank;World Trade OrganizationThe COVID-19 (coronavirus) pandemic has exposed the upsides and downsides of international trade in medical goods and services. Open trade can increase access to medical services and goods—and the critical inputs needed to manufacture them—improve quality and variety, and reduce costs. However, excessive concentration of production, restrictive trade policies, supply chain disruptions, and regulatory divergence can jeopardize the ability of public health systems to respond to pandemics and other health crises. Trade Therapy: Deepening Cooperation to Strengthen Pandemic Defenses, coordinated by Nadia Rocha and Michele Ruta at the World Bank and Marc Bacchetta and Joscelyn Magdeleine at the World Trade Organization, provides new data on trade in medical goods and services and medical value chains, surveys the evolving policy landscape before and during the pandemic, and proposes an action plan to improve trade policies and deepen international cooperation to deal with future pandemics. As the COVID-19 pandemic lingers, the focus of policy action is on the response, which includes actions aimed at removing bottlenecks and providing government support to promote equitable access to vaccines. As the emergency subsides, the focus should shift to prevention and preparedness. Steps to close information gaps—building on the Multilateral Leaders Task Force on COVID-19, the ACT-Accelerator, and the open markets, for example—by negotiating tariff reductions on medical goods and greater market access in services should take priority. Also important are measures to improve the efficiency of markets, which include harmonizing regulation through mutual recognition or equivalence of standards and creating international standards for essential medical goods, inputs, and production processes. Agreement on a crisis rulebook to be deployed during an emergency—including clear and agreed limits on export policy flexibility and shared rules on intellectual property flexibilities—would provide a more solid policy foundation to address future challenges.
Trade Union Strategies against Healthcare Marketization: Opportunity Structures And Local-level Determinants (Routledge Key Themes in Health and Society)
by Jennie AuffenbergMarketization in the healthcare sector affects the quality and delivery of care, as well as healthcare workers’ working conditions. Based on a comparison of England and Germany, along with an in-depth case study looking at New York, USA, this volume examines how trade unions respond to marketization processes and the determinants of successful strategies. The author draws on a rich empirical study to develop a theoretical framework that accounts for sector-specific opportunity structures stemming from marketization processes and on the relevant unions’ local-level leeway that opens if they build up and mobilise the available resources and capacities. The book identifies determinants of successful trade union strategies, explains the puzzling observation of similar strategic choices across different systems, and draws conclusions for prospects of trade unionism in the marketized healthcare sector. This book emphasizes the transformative effect of marketization on healthcare and the opportunities this change creates for unions, while giving special attention to the local-level conditions of trade unionism in the analysis of conflicts evolving around marketization in the hospital sector. It is of interest to academics and practitioners working in healthcare management, human resource management, and employment relations.