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Treatment of Non-infectious Uveitis
by Phoebe Lin Eric SuhlerThis unique, comprehensive book provides a much-needed reference on the treatment and management of non-infectious uveitis. Carefully designed, Treatment of Non-infectious Uveitis is the first book of its kind to provide an in-depth, clinically-relevant, expert-driven resource for ophthalmologists focusing on modalities of uveitis treatment, their mechanism of action, dosing, and side effects.Each chapter provides an introduction, mechanism of action, indication, dosage, side effects, and efficacy summaries from clinical trials and other published literature. Topics range from topical treatment, to locally administered therapy including drug-releasing implants, to systemic immunosuppressive treatments both tried and new, as well as surgical management, with each chapter highlighting important practice pearls as well as easy-reference dosing tables, side effects, and lab monitoring pertinent to the agents discussed. The book concludes with a discussion of novel approaches to the treatment of non-infectious uveitis, and special considerations when treating uveitis in the pediatric patient. The majority of patients with non-infectious uveitis are treated by comprehensive ophthalmologists, many of whom are less familiar with established treatment guidelines outlining the role of corticosteroids and immunomodulatory therapy. While the non-specialist, resident, or fellow is sure to benefit from this one-stop guide to uveitis treatment, retina and uveitis specialists alike will also appreciate the practice tips and thorough coverage of this expertly-written reference. Treatment of Non-infectious Uveitis is the ideal reference for all ophthalmologists who seek to improve their understanding of the causes of uveitis and learn how to best treat this condition.
Treatment of Non-vitamin K Antagonist Oral Anticoagulants
by Masaaki Uno Kuniaki OgasawaraThis book describes new concepts and strategies for the clinical application of non-vitamin K antagonist oral anticoagulants (NOACs) for stroke. Although vitamin K antagonists have traditionally been used for the prevention of stroke, there are some problems associated with their use, such as the risk of intracranial hemorrhage, the need for dietary restrictions, and individual variability. Recently, NOACs have been introduced as alternatives to traditional anticoagulants and are becoming an option for treating stroke patients around the globe. However, their use is not without risk. Each chapter describes the successful use of NOACs for stroke patients and discusses their future impact from various points of view. The book is primarily written for neurosurgeons and neurologists but is also of interest to cardiologists involved in stroke treatment.
Treatment of Pediatric Neurologic Disorders
by Harvey S. Singer Eric H. Kossoff Adam L. Hartman Thomas O. CrawfordThis reference discusses state-of-the-art methods for the management of children with conditions affecting the nervous system-providing over 80 chapters that outline direct, logical approaches to numerous pediatric neurologic disorders using clear tables, algorithms, and figures for quick reference to key material.
Treatment of Peritoneal Surface Malignancies
by Angelo Giorgio Enrico PintoThis monograph summarizes state of the art knowledge regarding peritoneal surface malignancies, with in-depth description of treatment options and the results achieved to date. It explores the most challenging problems on the basis of the authors' very extensive clinical experience and examines the most relevant clinical trials. A comprehensive summary is provided of all phase 2 studies (the only available completed studies) and of ongoing and future phase 3 studies. Particular attention is paid to the results of integrated treatment comprising cytoreduction (peritonectomy) and hyperthermic intraperitoneal chemotherapy (HIPEC). Helpful background information is also included on the definition and clinical assessment of each clinical form. The book, drawing on data from the entire Italian experience as well as world literature, will be an outstanding benchmark for health professionals and researchers.
Treatment of Postoperative Complications After Digestive Surgery
by Miguel A. Cuesta H. Jaap BonjerAny surgical intervention, elective or acute, may lead to postoperative complications. Moreover, the pertaining approach - laparoscopic or open - will probably not differ in the morbidity rate after surgery. Complications that occur after a surgical intervention can be classified as major or minor. Major complications to the digestive tract after surgery imply in most of cases a leakage of an anastomosis, bleeding in the abdominal cavity or in the tract, the appearance of intraperitoneal abscesses, or surgical site infections and wound dehiscence. These complications, depending on the organ affected, upper GI, HPB tract or colorectal, are associated with high morbidity and mortality. Early suspicion and diagnosis, followed by an early and effective treatment is imperative in order to reduce the morbidity and mortality. Adequate treatment will involve a good coordination of the three disciplines involved in treatment: the surgeon, the intervention radiologist, and the gastroenterologist. Approach of these postoperative complications is changing constantly and these changes are not properly known by general and more specialized digestive surgeons daily involved in the treatment of these diseases. The proposal for this book is to offer a systematic description of the most frequent complications occurring in the three above mentioned parts of the digestive tract. In this way, the reader will have access to a practical book in which every current complication can be easily recognized, along with relevant information as guide for an adequate treatment.
Treatment of Psychiatric Disorders Among Older Adults
by Rajesh R. Tampi Deena J. TampiThis timely book provides detailed information regarding the latest treatment for psychiatric disorders among the growing population of older adults. The World Health Organization reports that between 2015 and 2050, the proportion of the world's older adults (≥ 60 years) will double from about 12% to almost 22% of the total population, and it is estimated that approximately 20% of older adults have a diagnosable psychiatric disorder. Many of these older adults are prescribed psychotropic medications, but these treatments can result in significant functional decline, cognitive decline, cerebrovascular adverse events, and death. The editors, in collaboration with fellow experts in geriatric psychiatry, provide the scientific background regarding the treatment of a range of psychiatric disorders among older adults. The volume features a comprehensive table of contents covering a range of psychiatry subtopics, such as neurocognitive disorders, depressive disorders, substance use disorders, and anxiety disorders. Each chapter adheres to the same easy-to-follow format, and amongst other information, includes evidence-based assessments, non-pharmacological and pharmacological therapies, potential side-effects and their treatments, and evidence-based treatment algorithms for each disorder. Treatment of Psychiatric Disorders Among Older Adults will be a valuable resource for psychiatrists, geriatricians, students, neurologists, advance practice nurses, psychologists, social workers, occupational therapists, physical therapists, and dieticians who care for older adults with mental health disorders.
Treatment of Pulmonary Hypertension
by Brendan MaddenThis title will be presented as highly practical information on pharmaceutical options in pulmonary hypertension, written in a quick-access, no-nonsense format. The emphasis will be on a just-the-facts clinical approach, heavy on tabular material, light on dense prose. The involvement of the ISCP will ensure that the best quality contributors will be involved and establish a consistent approach to each topic in the series. Each volume is designed to be between 100 and 150 pages containing practical illustrations and designed to improve understand and practical usage of cardiovascular drugs in specific clinical areas.
Treatment of Refractory Renal Anemia: Case Collection
by Bi-Cheng LiuRenal anemia, one of the common complications in patients with chronic kidney disease, has a high prevalence and seriously affects the quality of life and prognosis of patients. This open access book provides advanced information on clinical management of renal anemia in difficult situations, which respond poorly to the existing treatment of recombinant human erythropoietin, iron and blood transfusion. Details of treatment of renal anemia in different types of patients are presented with comments from renowned nephrologist. It will be an ideal reference for practitioners and other healthcare professionals interested in learning more about renal anemia.
Treatment of Sex Offenders
by D. Richard Laws William O'DonohueThis rigorous survey offers a comprehensive rethinking of the assessment and treatment of sexual offenders for a bold challenge to practitioners. It critiques what we understand about offenders and the mechanisms of offending behaviors, and examines how this knowledge can best be used to reduce offending and relapses. To this end, experts weigh the efficacy of common assessment methods and interventions, the value of prevention programs, and the validity of the DSM's classifications of paraphilias. This strengths/weaknesses approach gives professional readers a guide to the current state as well as the future of research, practice, and policy affecting this complex and controversial field. Included in the coverage: Strengths of actuarial risk assessment. Risk formulation: the new frontier in risk assessment and management. Dynamic risk factors and offender rehabilitation: a comparison of the Good Lives Model and the Risk-Need-Responsivity Model. The best intentions: flaws in sexually violent predator laws. Desistance from crime: toward an integrated conceptualization for intervention. From a victim/offender duality to a public health perspective. A call to clear thought and accurate action, Treatment of Sex Offenders will generate discussion and interest among forensic psychologists, psychiatrists, clinical psychologists, and social workers.
Treatment of Skin Diseases: A Practical Guide
by Zohra Zaidi Khalid Hussain Simi SudhakaranThis book summarises the key clinical features and their treatment across a range of skin diseases and describes the decision-making process when referring patients to specialists. It describes how treatment of the skin is often very different to other specialities, as both topical and systemic medications are used, and reviews the clinical signs, investigation and diagnostic approaches to skin diseases. Treatment of Skin Diseases: A Practical Guide principally aids primary care physicians, trainee dermatologists and dermatology nurse practitioners, but it is also a convenient management guide for allied health professionals, students and hospital-based physicians. A concise atlas of diagnostic photographs is included and incorporated with a simple set of common differentials to provide a useful reference for primary care readers and those training in dermatology. The book also contains information on the management of common skin problems, together providing a comprehensive introduction to the treatment of skin diseases. The treatment options for secondary and tertiary care are also included to provide a thorough picture of the spectrum of dermatologic therapeutics.
Treatment of Spine Disease in the Elderly: Cutting Edge Techniques and Technologies
by Michael Y. Wang Praveen V. Mummaneni Kai-Ming G. Fu Michael S. Virk John R. Dimar IIAs the population continues to age worldwide, spinal disease will become more prevalent in the elderly population. The treatment of spinal disease requires an individual approach encorporating best practices. Optimal management in the elderly may differ from younger patients due to increased comorbidities, decreased bone health, and a higher risk of perioperative morbidity and mortality. While more and more elderly patients will require evaluation and management of their spinal disease, most modern books discuss operative and nonoperative management based upon disease process. Techniques and approaches are described for a specific pathology, and are usually tailored for a young or middle aged patient. Treatment of Spine Disease in the Elderly: Cutting Edge Techniques and Technologies is designed to address this gap in today’s literature by expressly addressing spinal conditions in the elderly and current advanced techniques and technologies for treating their spinal disease. It will be intended as a resource for the beginning to the advanced surgeon and practitioner whom undertakes treatment of patients in this age group.
Treatment of Substance Abuse: Psychosocial Occupational Therapy Approaches
by Diane GibsonThis timely volume fills a long-standing gap in the professional literature by providing an overview of contemporary assessment and rehabilitation of alcohol and chemical dependent substance abusers. Although many occupational therapists and other activity therapy staff work in substance abuse programs, few articles in occupational therapy literature address this relevant topic. Treatment of Substance Abuse: Psychosocial Occupational Therapy Approaches provides a unique overview of contemporary assessment and rehabilitiation of alcohol and chemical dependent substance abusers. The highlights of this insightful book include behavioral and educational frames of reference as well as specific treatment modalities such as stress management, activities of daily living, and leisure counseling. Contributors examine current polemics regarding programs that use methadone versus abstinence and theoretical concepts including the psychodynamic model with emphasis on the defensive structure underlying the abuser’s personality, as well as leveled conceptual framework for considering treatment. A number of practical techniques are discussed within the overall context of each article; hence the reader will find usable guidelines for establishing boundaries of treatment as well as discreet ideas about methods and practice. Roles and functions of varying disciplines are reviewed in an effort to discriminate role clarity and provide implications for practice in relation to different models. This issue is valuable to the OT who seeks an understanding of the varying viewpoints and current practice in the substance abuse field.
Treatment of Substance Use Disorders (Key Readings in Addiction Psychiatry)
by Kevin A. SevarinoFirst published in 2002. Routledge is an imprint of Taylor & Francis, an informa company.
Treatment of Thyroid Tumor
by Hitoshi Noguchi Takahiro Okamoto Yasuhiro Ito Hiroshi Takami Akira YoshidaCreating clinical guidelines is a modern trend. Published studies pertaining to a given theme are collected, their credibility evaluated, and then treatment options in the form of evidence-based guidelines are offered. There are a number of guidelines for the treatment of thyroid tumors that have established positions in clinical practice in North America and in Western European countries. In Japan, however, where radioisotope facilities are of limited availability, treatment plans for differentiated thyroid cancer differ considerably from those of America and Europe, and the associated clinical guidelines need modification before they can be adopted. In addition, although thyroid tumor is a common disease in endocrine practice, its management can differ even among specialists. Thus, a Japanese clinical guideline for the treatment of thyroid tumor was desired by many clinicians. As a combination of evidence-based and consensus-based guidelines for the treatment of thyroid tumor, this book offers alternatives to conventional approaches in the West. Ultimately, the authors hope the guideline will lead to the best possible treatment for patients all over the world in the not-distant future.
Treatment of the Obese Patient
by Robert F. Kushner and Daniel H. BessesenThis is a timely and informative updated edition for all health care providers challenged with helping patients manage weight. Similar to the well-reviewed first edition, this updated title is directed toward individuals who wish to read further about targeted topics, rather than find an introduction to the field. This second edition again provides insights into recent scientific advances in obesity research and provides the most up-to-date instruction about current treatment issues and strategies for both adults and children. While several of the chapters are no longer relevant from the first edition, other topics have emerged as interesting and current. This edition will keep the two-section format of Physiology and Pathophysiology and Clinical Management, but it increases the first section to 10 chapters and reduces the second section to 12 chapters. The plan is to keep this edition in the range of about 350 to 400, maximum, printed pages. The volume is again divided into two parts. Part 1 covers new discoveries in the physiological control of body weight, as well as the pathophysiology of obesity. Expert authors discuss pathways that control food intake, energy expenditure and peripheral nutrient metabolism, including a look at the emerging evidence of the role of adipose tissue as an endocrine organ. Part 2 covers all the key issues central to clinical management, including recent developments in the epidemiology of obesity, assessment of the obese patient, behavioral strategies in weight management, dietary modification as a weight management strategy, physical activity as a weight management strategy, weight loss drugs, surgical approaches to obesity and other important clinical topics. An essential, practical text that sorts, synthesizes and interprets the latest information on obesity-related topics, this second edition will be an essential resource for clinical endocrinologists and other health care providers across a broad spectrum of specialties.
Treatment or Diagnosis: A study of repeat prescriptions in general practice (Social Science Paperback Ser. #Vol. 253)
by John Hunt Marshall Marinker Michael Balint Dick Joyce Jasper WoodcockTavistock Press was established as a co-operative venture between the Tavistock Institute and Routledge & Kegan Paul (RKP) in the 1950s to produce a series of major contributions across the social sciences. This volume is part of a 2001 reissue of a selection of those important works which have since gone out of print, or are difficult to locate. Published by Routledge, 112 volumes in total are being brought together under the name The International Behavioural and Social Sciences Library: Classics from the Tavistock Press. Reproduced here in facsimile, this volume was originally published in 1970 and is available individually. The collection is also available in a number of themed mini-sets of between 5 and 13 volumes, or as a complete collection.
Treatment-Related Stroke
by Qureshi Adnan I. Alexander Tsiskaridze Arne LindgrenUp to 15% of all strokes occur in hospitalized patients, many of whom are there for surgical procedures or cardiac disorders. Outcomes can be poor, with high mortality - possibly related to co-morbidities and the complexities of hospital care. Risk factors for in-hospital stroke include specific operations and procedures (such as cardiac surgery), previous medical disorders (especially a history of stroke or transient ischemic attack), and certain physiological characteristics (including fever and dehydration). More rapid diagnosis and evaluation for interventional therapies is needed. This major new book examines the causes of treatment-related stroke in most hospital-based situations. Therapeutic approaches - including interventional therapies and intra-arterial thrombolysis - are highlighted, including experimental agents and interventions where other treatment possibilities are limited. Increasing the awareness of such interventions is an important factor in reducing delays in the assessment of patients who have strokes while in hospital, thus decreasing morbidity and reducing costs.
Treatment-Resistant Bipolar Disorder: Evidence-based Pharmacotherapy, Cognitive Behavioral Psychotherapy and Rehabilitation
by Stavroula Rakitzi Polyxeni GeorgilaTreatment resistant Bipolar Disorder is one of the most chronic mental health disorders, which are associated with high suicidality, poor adherence to therapy high percentage of hospitalizations and poor quality of life. Effective recovery-oriented treatments are necessary in order to avoid the above dangers. These therapies contribute to a new reintegration into society. They also help people to accept themselves and to fight against stigma. A new beginning is possible. This book introduces an integrative therapeutic model, which focuses on the combination of recovery-oriented pharmacotherapy and psychotherapy. Additionally, strategies of building a better therapeutic relationship are presented and discussed. This book is of interest for psychiatrists, psychology students, clinical psychologists and cognitive behavioral psychotherapists
Treatment-Resistant Depression
by Siegfried Kasper Stuart A. MontgomeryThe first book devoted to a challenging disorder that affects millions of people around the world. Essential reading for all psychiatrists who manage these patients.
Treatment-Resistant Schizophrenia: Evidence-based Pharmacotherapy, Cognitive Behavioral Psychotherapy and Rehabilitation
by Stavroula Rakitzi Polyxeni GeorgilaTreatment-resistant schizophrenia is one of the most challenging mental health disorders and is associated with a high risk of relapse, repeated hospitalizations, suicidal behavior and poor quality of life. This book focuses on treatment-resistant schizophrenia, its clinical features, and evidence-based treatments: pharmacotherapy, cognitive-behavioral psychotherapy, and rehabilitation. A novel therapy targeting long-term recovery for treatment-resistant schizophrenia is discussed. The cognitive, metacognitive, and recovery perspectives represent the main elements. Each chapter begins with an abstract, followed by learning objectives, introduction, main text, discussion, conclusion, review questions, and bibliography. This structure, including learning objectives and review questions, reinforces the reader's learning process. It can also help improve the teaching process in seminars and courses.
Treatments from Toxins: The Therapeutic Potential of Clostridial Neurotoxins
by Keith A. Foster Peter Hambleton Clifford C. ShoneAs little as two decades ago, deliberately injecting botulinum toxin into patients would have seemed foolhardy at best and criminal at worst. The increased clinical use of botulinum toxins has expanded the body of knowledge available on the structure and function of these proteins. This knowledge can be applied to topics as varied as therapies base
Tree-Shaped Fluid Flow and Heat Transfer (SpringerBriefs in Applied Sciences and Technology)
by António F. Miguel Luiz A. RochaThis book provides the first comprehensive state-of-the-art research on tree (dendritic) fluid flow and heat transfer. It covers theory, numerical simulations and applications. It can serve as extra reading for graduate-level courses in engineering and biotechnology. Tree flow networks, also known as dendritic flow networks, are ubiquitous in nature and engineering applications. Tree-shaped design is prevalent when the tendency of the flow (fluid, energy, matter and information) is to move more easily between a volume (or area) and a point, and vice versa. From the geophysical trees to animals and plants, we can observe numerous systems that exhibit tree architectures: river basins and deltas, lungs, circulatory systems, kidneys, vascularized tissues, roots, stems, and leaves, among others. Tree design is also prevalent in man-made flow systems, both in macro- and microfluidic devices. A vast array of tree-shaped design is available and still emerging in chemical engineering, electronics cooling, bioengineering, chemical and bioreactors, lab-on-a-chip systems, and smart materials with volumetric functionalities, such as self-healing and self-cooling. This book also addresses the basic design patterns and solutions for cooling bodies where there is heat generation. Several shapes of fin as well as assemblies of fins are addressed. An up-to-date review of cavities, i.e., inverted or negative fins, for facilitating the flow of heat is also presented. Heat trees using high thermal conductivity material can be used in the cooling of heat-generating bodies, and can also be applied to the cooling of electronics.
Trending Topics in Escherichia coli Research: The Latin American Perspective
by Alfredo G. TorresThe Latin American region has been at the forefront in combating infections caused by Escherichia coli strains in humans, animals, and the environment. The continuous emergence and evolution of pathogenic E. coli strains associated with human and animal infections have demonstrated that (i) groups of related pathogenic E. coli are responsible for most infections caused by this bacterial species; (ii) diverse virulence phenotypes expressed during infection defined each one of these pathogroups; (iii) the geographical distribution of pathogroups in Latin America and the evolution of new isolates was defined by the dominant pathogroup and presence of distinct virulence strains; (iv) acquisition of mobile elements or accumulation of point mutations accelerate the development of antibiotic resistance in some of these strains. The Latin American Coalition for Escherichia coli Research (LACER), a multidisciplinary network of over seventy research groups in eleven Latin American countries and the USA, was established in 2009 to apply One Health principles in defining and combating this pathogen. The previous edition of this text, Escherichia coli in the Americas (c. 2016) was the culmination of their wisdom about E. coli, from its role as a commensal bacterium to its characteristics as a pathogen causing disease in animals and humans. This new edition presents recent advances and contextualizes all aspects of E. coli in a One Health perspective, from the environment, to animals, to humans. It addresses E. coli interactions with host microbiota, CNS, and phages. It includes cutting edge insights on hybrid strains, molecular mechanisms of virulence and pathogenesis, resistance, domestic and wild reservoirs, disease surveillance in Latin America, genomic analysis, food safety, and new therapies. Crucially, it also provides translations and analysis of key reports on Escherichia coli published in Spanish and Portuguese. This book serves as a critical resource for scientists in industry and academia, clinicians managing associated infections, and trainees and students studying basic and clinical aspects of E. coli pathogenesis.
Trending in der pharmazeutischen Industrie (essentials)
by Patric U. VogelIn diesem Buch wird die Anwendung von Trendanalysen in pharmazeutischen Betrieben dargestellt. Trending ist ein Thema, das immer größere Bedeutung im GMP-Umfeld erlangt. Die Durchführung gängiger Trendanalyse-Methoden wird erklärt. Zudem werden die Stärken und Schwächen verschiedener Ansätze beschrieben. Anhand eines Beispiels wird dargestellt, wie Unternehmen durch Anwendung von Trending wirtschaftliche Verluste vermeiden können.
Trends in Antiviral Drug Development (Trends in Drug Discovery)
by David P. Rotella Wayne E. Childers János Fischer Christian KleinHard-to-find insights from industry professionals on success strategies for developing the next generation of antiviral blockbuster drugs Presented by industry professionals with a track record of discovering new drugs and treatments, Trends in Antiviral Drug Development describes successful development efforts for antiviral compounds and therapies that have entered the market or are currently in clinical trials. Viruses are ordered by their target tissue, in line with contemporary drug development that focuses on tissue-targeted therapeutics. Other key trends in antiviral therapy, such as the effort to develop long-acting drugs, are described for each virus type, enabling readers to follow the current and future state in this core area of contemporary drug development. Trends in Antiviral Drug Development includes discussion on: Novel drugs against herpes viruses as well as the breakthrough drugs that cured HCVsiRNA therapeutics, a new antiviral modality, and the drug candidates that are progressing toward achieving an HBV cureDrugs targeting viral entry, such as in HIV entry through attachment, co-receptor binding, and fusionNovel therapeutics against tropical diseases such as dengue fever and monkey pox Trends in Antiviral Drug Development is an essential read for medicinal chemists, pharmaceutical chemists, virologists, and all professionals seeking to understand new ideas and approaches to combat the ever-expanding universe of viral infections.