- Table View
- List View
Vascular Biomechanics: Concepts, Models, and Applications
by T. Christian GasserThis textbook serves as a modern introduction to vascular biomechanics and provides the comprehensive overview of the entire vascular system that is needed to run successful vascular biomechanics simulations. It aims to provide the reader with a holistic analysis of the vascular system towards its biomechanical description and includes numerous fully through-calculated examples. Various topics covered include vascular system descriptions, vascular exchange, blood vessel mechanics, vessel tissue characterization, blood flow mechanics, and vascular tissue growth and remodeling. This textbook is ideally suited for students and researchers studying and working in classical and computational vascular biomechanics. The book could also be of interest to developers of vascular devices and experts working with the regulatory approval of biomedical simulations.Follows the principle of “learning by doing” and provides numerous fully through-calculated examples for active learning, immediate recall, and self-examination;Provides a holistic understanding of vascular functioning and the integration of information from different disciplines to enable students to use sophisticated numerical methods to simulate the response of the vascular system;Includes several case studies that integrate the presented material. Case studies address problems, such as the biomechanical rupture risk assessment of Abdominal Aortic Aneurysms, Finite Element analysis of structural and blood flow problems, the computation of wall stress and wall shear stress in the aorta.
Vascular Complications of Surgery and Intervention: A Practical Guide
by Ramyar Gilani Joseph L. MillsThe concept for this book evolved over many years of intense clinical practice during which a wide variety of vascular complications were encountered as a result of other surgical or interventional procedures. In this book, the authors describe cohesive efforts by experts in the field as they commit to advancing health care quality by all professionals. It should be noted at the outset that the book does not discuss various non-vascular or systemic complications of patients undergoing vascular interventions such as myocardial infarction, renal or respiratory failure. Instead, the content is divided into four separate sections. The material begins with an introduction to vascular anatomy and function. There follows a section addressing specific complications of the vascular system that can occur in any patient, sometimes even without intervention. The third section addresses complications specific to interventions and surgical procedures. The final section is dedicated to the delayed and long-term sequelae attributable to the most commonly encountered vascular complications.Vascular Complications of Surgery and Intervention: A Practical Guide is targeted towards dedicated health care professionals managing patients affected by inadvertent but potentially disastrous vascular complications and for those practitioners performing interventions either directly upon the vascular system or procedures that have potential for collateral impact.
Vascular Control of Hemostasis
by Victor vanHinsberghHemostasis represents a group of balanced activities that keep the blood flowing It is a complete response system which has developed to guarantee blood fluidity and to limit blood loss after wounding, and adapts after exposure to infectious micro-organisms The failure of this control system causes ischemia, severe damage to the distal tissues and, ultimately, death This book provides an up-to-date and comprehensive account of the control of hemostasis by vascular cells It is an indispensable guide for researchers in hemostasis and vascular biology, from the post-graduate level onwards It will also be of great interest to clinicians in vascular medicine and cardiology Topics covered include: hemostatic properties of the vessel wall; anticoagulant properties of the vessel wall; other aspects of coagulation; and changes in vascular hemostatic properties
Vascular CT Angiography Manual
by Robert Pelberg Wojciech MazurDespite the exponential growth in the use of peripheral CTA in the diagnosis and follow-up of vascular disease patients, practical sources from which to gain valuable expertise in this field remain scarce. There is becoming a great need for experts in the field of peripheral CTA, yet learning this imaging modality may be intimidating and time consuming. Very few if any, small, concise and portable books exist to ease training in this field and current books in this field are overwhelming, difficult to manage, text books that often combine CTA and MRI. A so called " how to manual" and reference guide to explain this technique from beginning to end, which compiles valuable, and difficult to obtain clinical pearls and descriptions of disease processes will be of tremendous value. The Peripheral CT Angiography Manual aims to make learning this intimidating technique and the diseases for which it applies simple and fun.
Vascular Damage in Neglected Tropical Diseases: A Surgical Perspective
by Valeria Silvestri Vivian Mushi Billy NgasalaIn the realm of surgical pathology, specifically within regions endemic to neglected tropical diseases (NTDs), this book serves as a comprehensive reference on nonclassical vascular risk factors from an epidemiological standpoint. It addresses the often-overlooked issue of vascular damage in patients afflicted with parasitic diseases and other NTDs. Current literature primarily consists of rare individual case reports and case series for each specific disease, making this book a valuable contribution to the field. The book describes various aspects related to vascular involvement in NTDs, including parasitological, vector borne diseases and snakebite-associated vascular lesions. Although these cases and their underlying pathophysiologic mechanisms are rarely reported and remain understudied, this book describes the various nuances of surgical vascular pathology in this setting, encouraging further research in this area. Five main topics are covered: the vascular problems in patients with 1. Schistosomiasis, 2. Amebiasis, 3. Hydatidosis, 4. Lymphatic filariasis, and 5. Snakebites. This work raises awareness of these rarely reported diseases in areas where they are more common or in countries where they are imported, among physicians directly involved in the management of these cases. It serves as a guide to treatment from presentation through the various steps of patient care. The book is a reference for all professionals concerned with morbidity associated with neglected tropical diseases, particularly vascular morbidity of surgical interest, both research and clinical, in endemic and non-endemic settings. It is a valuable resource for the continuing education of health professionals working in this field. It serves as a textbook for vascular surgery fellows interested in non-classical cardiovascular risk factors leading to surgical conditions. This specific topic related to non-communicable comorbidities in diseases of parasitological interest is useful for parasitologists and public health specialists at master level and above.
Vascular Disease
by Andrew H. BakerAndrew Baker and a noted panel of expert investigators describe today's most powerful molecular methods for investigating the pathogenesis of vascular disease. These detailed, easy-to-follow techniques range from methods that have been used successfully to identify specific mutations involved in cardiovascular disorders, to those for transferring genes associated with cardiovascular disease into various vascular cell types by in vitro and in vivo routes. There are methods to identify novel genes and generate full-length cDNAs, to study gene transcription and promoter activity easily and effectively, and to ascertain precisely gene expression levels within the individual cell types in different pathophysiological conditions. Vascular Disease: Molecular Biology and Gene Therapy Protocols offers today's vascular biologist and gene therapist an unprecedented ability to study the pathogenesis of vascular disease and readily to probe the potential for gene-based therapies.
Vascular Disease in Older Adults
by Rabih ChaerThis book presents acomprehensive and state-of the-art approach to vascular disease for the geriatricpatient, focusing on vascular pathology and interventions but also onperioperative care, anesthetic care, functional outcomes and quality of life,as well as ethical considerations that impact decision making. The bookaddresses open and endovascular interventions in different vascular beds, aswell as preoperative workup and optimization, anesthetic considerations, allaspects and expectations of the postoperative care and recovery and is the onlybook to include specialize in the intricacies of the care of the geriatricpatients, the challenging recovery and neurocognitive changes, and ethicalconsiderations for the end stage geriatric patient or in the setting ofpostoperative complications. Written by experts in the field, each section addressespatient selection, pre-operative considerations, technical conduct of the mostcommon operations with open or endovascular options, and avoidingcomplications. A brief review of the existing literature addressing theparticular topic follows in each section. Extensive illustrations, angiographicimages, and treatment algorithms, as well as a summary bullet point table ofthe key messages at the end of each chapter makes this an interactive text. With its concise yetcomprehensive summary of the field, Care of the Elderly Patient With VascularDisease is the ultimate resource for physicians of different specialties whocare for the geriatric patient with vascular disease.
Vascular Diseases for the Non-Specialist
by Tulio Pinho Navarro Alan Dardik Daniela Junqueira Ligia CisnerosThis book aims to provide non-specialist healthcare practitioners with current, focused and objective information on the most common vascular diseases encountered in daily clinical practice. In day-to-day clinical practice many healthcare practitioners do not have a working knowledge of the most common vascular diseases that frequently arise in patient care. Some of these topics include: aneurysms, peripheral arterial disease, diabetic foot, venous thromboembolism, cerebrovascular disease, aortic dissection, and acute limb ischemia. These commonly encountered vascular diseases are becoming public health issues due to their high morbidity and mortality as well as increasing healthcare costs. Since patients with vascular diseases are often referred to non-specialists, the general practitioner must know how to proper handle the most common vascular diseases encountered in daily clinical practice. For each disease the concept, epidemiology, natural history, diagnosis and treatment are described, followed by essential advice on what the non-specialist can do for the patient and when to refer the patient to a specialist.
Vascular Disorders of the Liver: VALDIG's Guide to Management and Causes
by Dominique Valla Juan Carlos Garcia-Pagan Andrea De Gottardi Pierre-Emmanuel RautouThis book provides a comprehensive account on individually rare, but collectively frequent diseases of the liver. In the first part, conditions such as hepatic vascular malformations, ischemic cholangiopathy, hepatic artery occlusion, sinusoidal conditions and Budd-Chiari syndrome are discussed among others. The second part examines the causes of vascular liver disease namely, coagulation disorders, neoplasm disorders, non-malignant blood disorders, systemic diseases and toxins, among others. The unique expertise of the authors, who are all members of the Vascular Liver Disease Disorders Group, an independent network of researchers with a common interest in Vascular Liver Diseases, are merged for an optimal pragmatic and individualized approach. This book is of interest to a broad range of experts, such as hepatologists, internists, radiologists and angiologists.
Vascular Disruptive Agents for the Treatment of Cancer
by Tim MeyerTumour survival and growth is critically dependent on an independent blood supply. As such tumour vasculature presents an ideal target for cancer therapy that is widely applicable, accessible and genetically stable rendering it less prone to resistance. Two approaches have been explored for cancer therapy; firstly the prevention of new vessel formation with inhibitors of angiogenesis, and secondly the destruction of existing tumour blood vessels with so called vascular disruptive agents (VDAs). While the first approach appears to delay tumour progression, the second has the potential to cause massive cell death and tumour regression. It si the second approach of vascular targeting that is the focus of this review. Since the tubulin binding agent combretastatin, derived from the bark of the African bush willow, was discovered by George R Pettit to have antimitotic properties over twenty years ago, the field of vascular targeting has expanded steadily. Coincident with the preclinical and clinical development of these agents, there have been advances in our understanding of their mechanism of action and in the technology required to assess their effects.
Vascular Effects of Hydrogen Sulfide: Methods and Protocols (Methods in Molecular Biology #2007)
by Jerzy BełtowskiThis book explores techniques for exploring hydrogen sulfide (H2S) and its effects on the vascular system through numerous experimental animal models and vascular preparations. Alterations of vascular H2S generation/signaling may be involved in the pathogenesis of systemic and pulmonary arterial hypertension, ischemic heart disease, ischemic stroke, preeclampsia, and erectile dysfunction, and H2S also serves as an attractive target for pharmacotherapy of cardiovascular diseases, as well as possible effects on cancer, wound healing, and diabetic retinopathy, among other pathologies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Vascular Effects of Hydrogen Sulfide: Methods and Protocols is an ideal aid for scientists working to extend our knowledge in this valuable and wide-ranging field of study.
Vascular Endothelium in Human Physiology and Pathophysiology
by Patrick J Vallance David J. WebbEndothelial dysfunction is now regarded as an early marker of vascular disease and therefore an important target for therapeutic intervention and discovery of novel treatments. Ideal for both basic and clinical scientists, whether in industry or academia, and physicians, Vascular Endothelium in Human Physiology and Pathophysiology provides an up-to
Vascular Engineering
by Kazuo Tanishita Kimiko YamamotoThis book describes the fundamental biology and mechanics of the vasculature and examines how this knowledge has underpinned the development of new clinical modalities, including endovascular treatment and vascularization of reconstructed tissue for regenerative medicine. Vascular engineering is a multidisciplinary field integrating vascular biology, hemodynamics, biomechanics, tissue engineering, and medicine. Each chapter offers insights into the dynamics of the circulatory system and explains how the impact of related disease conditions -- atherosclerosis, hypertension, myocardial ischemia, and cerebral infarction -- has generated a focus on developing expertise to both maintain and treat the vascular system. As a comprehensive book in this expanding area, Vascular Engineering serves as a valuable resource for clinicians as well as academics and professionals working in biophysics, biomedical engineering, and nano and microrheology. Graduate students in these subject areas will also find this volume insightful.
Vascular Hyperpermeability: Methods and Protocols (Methods in Molecular Biology #2711)
by Binu TharakanThis volume focuses on the latest research methods and techniques used by researchers to study vascular permeability/hyperpermeability in a science laboratory setting. The chapters in this book cover topics such as determination of solute permeability of microvascular endothelial cell monolayers in vitro; evaluation of barrier integrity used in a two-layered microfluidic device mimicking the blood-brain barrier; isolation and culture of human umbilical vein endothelial cells; measurement of blood-brain barrier hyperpermeability using Evans Blue extravasation assay; lymphatic vascular permeability determined from direct measurements of solute flux; intravital imaging of leukocyte-endothelial interaction by intravital multiphoton microscopy; and evaluation of tight junction integrity in brain endothelial cells using confocal microscopy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Thorough and cutting-edge, Vascular Hyperpermeability: Methods and Protocols is a valuable resource that will aid novice researchers with creating new and affordable research projects, and for expert researchers to initiate new strategies and collaborations in their ongoing programs.
Vascular Imaging of the Central Nervous System
by Mauricio Castillo Joana RamalhoThe first book-length reference to thoroughly describe diagnostic and therapeutic advances in the development of vascular radiology over the last decadeThe last ten years has seen vascular imaging of the central nervous system (CNS) evolve from fairly crude, invasive procedures to more advanced imaging methods that are safer, faster, and more precise--with computed tomographic (CT) and magnetic resonance (MR) imaging methods playing a special role in these advances.Vascular Imaging of the Central Nervous System is the first full-length reference text that shows radiologists--especially neuroradiologists--how to optimize the use of the many techniques available in order to increase the sensitivity and specificity of vascular imaging, thereby improving the diagnosis and treatment of individual patients. Each chapter is formatted carefully and divided into two essential parts: The first part describes the physical principles underlying each imaging technique, along potential associated artifacts and pitfalls; the second part addresses clinical applications and novel applications of each method.With a strong focus on the clinical application of each modality or technique in CNS radiology, this book provides in-depth chapter coverage of:* Ultrasound Vascular Imaging (UVI)* Computed Tomography Angiography (CTA)* Magnetic Resonance Vascular imaging (MRV)* Digital subtraction angiography (DSA)* Brain perfusion techniques: CT and MRI* Plaque imaging* Intravascular imaging* Pediatric vascular imagingAlong with numerous illustrations and case studies, Vascular Imaging of the Central Nervous System: Physical Principles, Clinical Applications, and Emerging Techniques is an important book for those faced with choosing from the wide range of choices available for clinical practice.
Vascular Interventional Radiology
by Mark G. CowlingThis new edition of Vascular Interventional Radiology: Current Evidence in Endovascular Surgery provides a thorough yet succinct and accessible review of the latest knowledge in the field of endovascular surgery. All chapters have been updated to reflect the advances that have occurred during the past five years, and new chapters are included on carotid artery stenting and day case intervention. The chapter on lower limb veno-occlusive disease has been expanded to include management of deep venous thrombosis. Among the other topics considered are the endovascular treatment options in different arterial territories, aneurysm repair techniques, and the management of venous stenosis and venous insufficiency. The aim throughout is to tackle issues of evidence-based practice in order to assist trainees and experienced practitioners in making and implementing treatment decisions. This book will be an invaluable source of information for both interventional radiologists and vascular surgeons with an interest in endovascular techniques.
Vascular Ion Channels in Physiology and Disease
by Irena Levitan Alex M. DopicoIon channels are the major class of membrane proteins responsible for rapid and regulated transport of ions across biological membranes and for the generation and propagation of electrical signals in the brain, heart, and skeletal and vascular tissues. Ion channels are also known to play critical roles in regulation of cell proliferation, insulin secretion and intracellular signaling in a variety of cell types. This book focuses on the roles of ion channels in vascular tissues under normal and pathological conditions. Vascular abnormalities are known to underlie a plethora of severe pathological conditions, such as atherosclerosis, systemic and pulmonary hypertension, coronary or cerebral vasospasm, and diabetes. In addition, misregulated angiogenesis is one of the major contributors to the development of tumors. Therefore, it is clearly imperative to obtain a better understanding of the molecular mechanisms that contribute to vascular disorders. This book will be the first comprehensive assembly of assays to present the studies that have been done during the last decade to elucidate the roles of ion channels in different vascular diseases.
Vascular Liver Disease
by Laurie D. Deleve Guadalupe Garcia-TsaoVascular Liver Disease: Mechanisms and Management covers all of the disease entities that stem from abnormalities that affect the hepatic vasculature. This multi-authored text includes the mechanisms and management of intrahepatic vascular disease, including the most common cause of vascular disease of the liver, cirrhosis. Other less common diseases of the liver vasculature are also covered such as sinusoidal obstruction syndrome (previously known as veno-occlusive disease), portal vein thrombosis, the Budd-Chiari syndrome and congenital vascular malformations. These entities, although rare, are a challenge to physicians and physician scientists. Although many textbooks have been written on the consequences of cirrhosis on the liver vasculature, this is the only volume that focuses on the liver vasculature as a separate entity, providing an innovative approach to liver disease management. Vascular Liver Disease: Mechanisms and Management will be of great value to clinical investigators and basic scientists interested in the liver circulation as well as clinical gastroenterologists and hepatologists, hepatobiliary surgeons and transplant surgeons, and to interventional radiologists with a particular interest in the liver.
Vascular Malformations: Advances and Controversies in Contemporary Management
by Byung-Boong Lee, Peter Gloviczki, Francine Blei and Jovan N. MarkovicThis new book on vascular malformations brings together international experts to present advances and discuss controversies in the multidisciplinary management of patients with congenital vascular malformations. Major advances in recent years in medical genetics, and tremendous progress in the fields of imaging and minimally invasive percutaneous interventions have revolutionized both evaluation and management of vascular malformations. The six major parts of this state of the art book ensure that the reader has the most up to date valuable clinical information to ensure the delivery of world class clinical practice. Beautifully illustrated with color line drawings, numerous photographs and informative tables, the advances and controversies of the full spectrum of vascular malformations are presented in 90 definitive chapters. Vascular Malformations brings new information and unparalleled insights to vascular specialists and physicians, trainees and allied health professionals who participate in the care of patients with vascular malformations, either in a private practice setting or at a major institution in an interdisciplinary vascular center.
Vascular Malformations
by Ajay K. Khanna Satyendra K. TiwaryThe book covers all aspects of vascular malformations including classification, embryology, genetics, clinical approach, investigations, management, controversies and key points to remember. Chapters cover recent changes in detail in various aspects, such as classification, genetic decoding, minimal intervention, selective approach and investigations for different types. It offers clear guidance on diagnostic protocol and surgical decision making with changing scenario leading to evolving endovascular and radiological interventions. The book is useful for vascular surgeon, pediatric surgeon, general surgeon, plastic surgeon and intervention radiologist as well as clinical research scholars, surgical oncologists and radiologists.
Vascular Manifestations of Systemic Autoimmune Diseases
by Ronald A. Asherson Ricard CerveraNot too long ago, it was thought that inflammation of blood vessels was the sole manifestation of systemic autoimmune diseases. Today, however, we know that disorders of coagulation, injuries to both neutrophils and endothelial cells, and certain lipids and amino acids are all intricately involved in the development of vascular disease. How are all
Vascular Mechanisms in CNS Trauma
by Eng H. Lo Josephine Lok Mingming Ning Michael J. WhalenWhile there are a number of books on the market that deal with neuronal mechanisms and targets, the proposed book will be the only one to cover the vascular aspects of CNS trauma. The contributing authors will present basic mechanisms, explain cutting-edge experimental models and techniques, and provide several clinical chapters that provide treating physicians with some insight on the cases that they see in the ICU. The table of contents is diverse and comprehensive with chapters on molecular mechanisms, physiology, pharmacology, stem cells, genomics and proteomics, in vivo MRI and PET, as well as the clinical management of vascular parameters.
Vascular Mechanobiology in Physiology and Disease (Cardiac and Vascular Biology #8)
by Markus Hecker Dirk J. DunckerThis volume of the series Cardiac and Vascular Biology presents the most relevant aspects of vascular mechanobiology along with many more facets of this fascinating, timely and clinically highly relevant field. Mechanotransduction, mechanosensing, fluid shear stress, hameodynamics and cell fate, are just a few topics to name. All important aspects of vascular mechanobiology in health and disease are reviewed by some of the top experts in the field. This volume, together with a second title on cardiac mechanobiology featured in this series, will be of high relevance to scientists and clinical researchers in the area of vascular biology, cardiology and biomedical engineering.
Vascular Morphogenesis
by Domenico RibattiVascular Morphogenesis: Methods and Protocols provides a range of techniques for studying vascular morphogenesis in vivo and in vitro, reflecting advances in the field. Endothelial cell signaling is currently believed to promote fundamental cues for cell fate specification, embryo patterning, organ differentiation and postnatal tissue remodeling. Understanding the concept of vascular bed specificity represents a major challenge for future investigations. Indeed, one of the most interesting theoretical perspectives and practical applications of endothelial cell signaling is the possibility for these cells to maintain their inductive potential during adult life. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Vascular Morphogenesis: Methods and Protocols will serve as a instructive and useful reference for cell biologists, anatomists, pathologists and physiologists, as well as all those interested in this area of biological study.
Vascular Neurology Board Review
by Hardik P. Amin Joseph L. SchindlerThis concise, yet comprehensive review covers the diagnostic and treatment information needed for the vascular neurology board exam. The assembled material is easy-to-read with chapters emphasizing clinically relevant scientific principles that must be mastered by the stroke clinician. Neurology, vascular neurology and neuro-critical care residents and fellows will find this text to be an invaluable preparation guide and a succinct source to complement treatment guidelines and protocols.