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Virtual Reality for Serious Illness
by Kathleen D. Benton Teri YarbrowVirtual Reality for Serious Illness explores the important role virtual-reality interventions can play in symptom management, anxiety control, and spiritual meaning. This book focuses on cutting-edge research and its effects on the seriously ill and those who treat the seriously ill. The innovation in this book is twofold: It is a global look at the use of virtual reality in complex medical cases where it takes an interdisciplinary look at use of virtual reality, and it includes a strong focus on the spiritual healing resulting from the meaning and purpose found during this intervention.The book is written for professionals who use holistic healing measures in the scope of treatment for chronic and seriously ill patients. It is written for all disciplines acting in holistic healthcare healing, including physicians, chaplains, nurses, and informatics interventionists.
Virtual Reality Games for Rehabilitation (Virtual Reality Technologies for Health and Clinical Applications)
by Eva Brooks David J. BrownThis volume focuses on games to manage and facilitate rehabilitation. It emphasizes user practice, attitudes, and experience, and their changing place within developing rehabilitation frameworks. It looks at how users have adopted, integrated, and innovated with games to facilitate rehabilitation. Topics include game technology, game design and accessibility, web-based technologies vs pervasive and mobile technologies, social and collaborative aspects, and rehabilitative outcome. Games for rehabilitation are gaining interest from different communities such as medicine, psychology, and rehabilitation. A distinction can be made between games specifically made for rehabilitative purposes and games made for the general public but that are used in rehabilitation as well. Games have allowed the building of new/complementary forms for rehabilitation and offered new options to produce rehabilitative activities and experiences.
Virtual Reality in Behavioral Neuroscience: New Insights and Methods (Current Topics in Behavioral Neurosciences #65)
by Christopher Maymon Gina Grimshaw Ying Choon WuVirtual Reality (VR) is a rapidly maturing technology that offers new and unique solutions to otherwise intractable problems in the study of cognition, behavior and neuroscience. VR removes many of the constraints imposed by laboratory paradigms, allowing us to track cognitive, behavioral and brain responses to naturalistic (or even impossible) situations without sacrificing experimental control. But VR is not a tool that can be swiftly and effortlessly integrated into existing research pipelines; currently, the benefits of VR are accompanied by a host of methodological challenges and important practical considerations. To help navigate this new methodology, this volume provides a balanced review of both the exciting new findings emerging from VR labs and the challenges and limitations that are part and parcel of VR research. This volume is an important first step toward establishing a standardised methodology for conducting research in VR. To this end, the volume provides a wealth of practical advice for researchers who are new to the technology. This volume is authored by an interdisciplinary team of VR researchers including computer scientists, engineers, psychologists and neuroscientists. It highlights current research in the field to demonstrate how VR advances our understanding of the mind, while also providing groundbreaking solutions in applied domains.
Virtual Reality in Health and Rehabilitation (Rehabilitation Science in Practice Series)
by Christopher M. Hayre Dave J. Muller Marcia J. SchererThis edited book focuses on the role and use of VR for healthcare professions in both health and rehabilitation settings. It is also offers future trends of other emerging technology within medicine and allied health professions. This text draws on expertise of leading medical practitioners and researchers who utilise such VR technologies in their practices to enhance patient/service user outcomes. Research and practical evidence is presented with a strong applied emphasis to further enhance the use VR technologies within the community, the hospital and in education environment(s). The book may also be used to influence policymakers on how healthcare delivery is offered.
Virtual Reality in Medicine
by Robert Riener Matthias HardersVirtual Reality has the potential to provide descriptive and practical information for medical training and therapy while relieving the patient or the physician. Multimodal interactions between the user and the virtual environment facilitate the generation of high-fidelity sensory impressions, by using not only visual and auditory, but also kinesthetic, tactile, and even olfactory feedback modalities. On the basis of the existing physiological constraints, Virtual Reality in Medicine derives the technical requirements and design principles of multimodal input devices, displays, and rendering techniques. Resulting from a course taught by the authors, Virtual Reality in Medicine presents examples for surgical training, intra-operative augmentation, and rehabilitation that are already in use as well as those currently in development. It is well suited as introductory material for engineering and computer science students, as well as researchers who want to learn more about basic technologies in the area of virtual reality applied to medicine. It also provides a broad overview to non-engineering students as well as clinical users, who desire to learn more about the current state of the art and future applications of this technology.
Virtual Screening: Principles, Challenges, and Practical Guidelines (Methods and Principles in Medicinal Chemistry #48)
by Raimund Mannhold Hugo Kubinyi Gerd FolkersDrug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in the human body. If the three-dimensional structures of both the small and large molecule are known, their interaction can be tested by computer simulation with a reasonable degree of accuracy. Alternatively, if active ligands are already available, molecular similarity searches can be used to find new molecules. This virtual screening can even be applied to compounds that have yet to be synthesized, as opposed to "real" screening that requires cost- and labor-intensive laboratory testing with previously synthesized drug compounds. Unique in its focus on the end user, this is a real "how to" book that does not presuppose prior experience in virtual screening or a background in computational chemistry. It is both a desktop reference and practical guide to virtual screening applications in drug discovery, offering a comprehensive and up-to-date overview. Clearly divided into four major sections, the first provides a detailed description of the methods required for and applied in virtual screening, while the second discusses the most important challenges in order to improve the impact and success of this technique. The third and fourth, practical parts contain practical guidelines and several case studies covering the most important scenarios for new drug discovery, accompanied by general guidelines for the entire workflow of virtual screening studies. Throughout the text, medicinal chemists from academia, as well as from large and small pharmaceutical companies report on their experience and pass on priceless practical advice on how to make best use of these powerful methods.
Virtual Screening in Drug Discovery
by Juan Alvarez Brian ShoichetVirtual screening can reduce costs and increase hit rates for lead discovery by eliminating the need for robotics, reagent acquisition or production, and compound storage facilities. The increased robustness of computational algorithms and scoring functions, the availability of affordable computational power, and the potential for timely structural
Virtual You: How Building Your Digital Twin Will Revolutionize Medicine and Change Your Life
by Peter Coveney Roger HighfieldThe visionary science behind the digital human twins that will enhance our health and our futureVirtual You is a panoramic account of efforts by scientists around the world to build digital twins of human beings, from cells and tissues to organs and whole bodies. These virtual copies will usher in a new era of personalized medicine, one in which your digital twin can help predict your risk of disease, participate in virtual drug trials, shed light on the diet and lifestyle changes that are best for you, and help identify therapies to enhance your well-being and extend your lifespan—but thorny challenges remain.In this deeply illuminating book, Peter Coveney and Roger Highfield reveal what it will take to build a virtual, functional copy of a person in five steps. Along the way, they take you on a fantastic voyage through the complexity of the human body, describing the latest scientific and technological advances—from multiscale modeling to extraordinary new forms of computing—that will make “virtual you” a reality, while also considering the ethical questions inherent to realizing truly predictive medicine.With an incisive foreword by Nobel Prize–winning biologist Venki Ramakrishnan, Virtual You is science at its most astounding, showing how our virtual twins and even whole populations of virtual humans promise to transform our health and our lives in the coming decades.
A Virtue-Based Defense of Perinatal Hospice (Routledge Annals of Bioethics)
by Aaron D. CobbPerinatal hospice is a novel form of care for an unborn child who has been diagnosed with a significantly life-limiting condition. In this book, Aaron D. Cobb develops a virtue-based defense of the value of perinatal hospice. He characterizes its promotion and provision as a common project of individuals, local communities, and institutions working together to provide exemplary care. Engaging with important themes from the work of Alasdair MacIntyre and Robert Adams, he shows how perinatal hospice manifests virtues crucial to meeting the needs of families in these difficult circumstances. As a work of applied virtue ethics, this book has important normative, social, and political implications for the creation and development of structured programs of care. It grounds the view that communities ought (i) to devote resources to ensure that these programs are widely available and (ii) to develop social structures that promote awareness of and accessibility to these forms of care. A Virtue-Based Defense of Perinatal Hospice will be of interest to philosophers working in bioethics and applied virtue ethics, as well as scholars in the fields of neonatology, nursing, palliative and hospice care, and counseling who are interested in the study of perinatal hospice.
Virtue Ethics and Human Enhancement
by Barbro FrödingThis book shows how pressing issues in bioethics - e.g. the ownership of biological material and human cognitive enhancement - successfully can be discussed with in a virtue ethics framework. This is not intended as a complete or exegetic account of virtue ethics. Rather, the aim here is to discuss how some key ideas in Aristotle's Nicomachean Ethics, when interpreted pragmatically, can be a productive way to approach some hot issues in bioethics. In spite of being a very promising theoretical perspective virtue ethics has so far been underdeveloped both in bioethics and neuroethics and most discussions have been conducted in consequentialist and/or deontological terms.
The Virtuous Physician
by James A. MarcumAlthough modern medicine enjoys unprecedented success in providing excellent technical care, many patients are dissatisfied with the poor quality of care or the unprofessional manner in which physicians sometimes deliver it. Recently, this patient dissatisfaction has led to quality-of-care and professionalism crises in medicine. In this book, the author proposes a notion of virtuous physician to address these crises. He discusses the nature of the two crises and efforts by the medical profession to resolve them and then he briefly introduces the notion of virtuous physician and outlines its basic features. Further, virtue theory is discussed, along with virtue ethics and virtue epistemology, and specific virtues, especially as they relate to medicine. The author also explores the ontological priority of caring as the metaphysical virtue for grounding the notion of virtuous physician, and two essential ontic virtues--care and competence. In addition to this, he examines the transformation of competence into prudent wisdom and care into personal radical love to forge the compound virtue of prudent love, which is sufficient for defining the virtuous physician. Lastly, two clinical case stories are reconstructed which illustrate the various virtues associated with medical practice, and it is discussed how the notion of virtuous physician addresses the quality-of-care and professionalism crises.
Virulence Mechanisms of Bacterial Pathogens (ASM Books)
by Indira T. Kudva Nancy A. Cornick Paul J. Plummer Qijing Zhang Tracy L. Nicholson John P. Bannantine Bryan H. BellaireGround-breaking overview of an enduring topic Despite the use of antibiotics, bacterial diseases continue to be a critical issue in public health, and bacterial pathogenesis remains a tantalizing problem for research microbiologists. This new edition of Virulence Mechanisms of Bacterial Pathogens broadly covers the knowledge base surrounding this topic and presents recently unraveled bacterial virulence strategies and cutting-edge therapies. A team of editors, led by USDA scientist Indira Kudva, compiled perspectives from experts to explain the wide variety of mechanisms through which bacterial pathogens cause disease: the host interface, host cell enslavement, and bacterial communication, secretion, defenses, and persistence. A collection of reviews on targeted therapies rounds out the seven sections of this unique book. The new edition provides insights into some of the most recent advances in the area of bacterial pathogenesis, including how metabolism shapes the host-pathogen interface interactions across species and genera mechanisms of the secretion systems evasion, survival, and persistence mechanisms new therapies targeting various adaptive and virulence mechanisms of bacterial pathogens Written to promote discussion, extrapolation, exploration, and multidimensional thinking, Virulence Mechanisms of Bacterial Pathogens serves as a textbook for graduate courses on bacterial pathogenesis and a resource for specialists in bacterial pathogenicity, such as molecular biologists, physician scientists, infectious disease clinicians, dental scientists, veterinarians, molecular biologists, industry researchers, and technicians.
Virulent Zones: Animal Disease and Global Health at China's Pandemic Epicenter (Experimental Futures)
by Lyle FearnleyScientists have identified southern China as a likely epicenter for viral pandemics, a place where new viruses emerge out of intensively farmed landscapes and human--animal interactions. In Virulent Zones, Lyle Fearnley documents the global plans to stop the next influenza pandemic at its source, accompanying virologists and veterinarians as they track lethal viruses to China's largest freshwater lake, Poyang Lake. Revealing how scientific research and expert agency operate outside the laboratory, he shows that the search for origins is less a linear process of discovery than a constant displacement toward new questions about cause and context. As scientists strive to understand the environments from which the influenza virus emerges, the unexpected scale of duck farming systems and unusual practices such as breeding wild geese unsettle research objects, push scientific inquiry in new directions, and throw expert authority into question. Drawing on fieldwork with global health scientists, state-employed veterinarians, and poultry farmers in Beijing and at Poyang Lake, Fearnley situates the production of ecological facts about disease emergence inside the shifting cultural landscapes of agrarian change and the geopolitics of global health.
Virus: Vaccinations, the CDC, and the Hijacking of America's Response to the Pandemic
by Nina BurleighNew York Times bestselling author Nina Burleigh weaves together the key narrative strands to create an uncompromising and highly informed expose about our shared global pandemic experience and what it means for our future Virus: Vaccinations, the CDC, and the Hijacking of America&’s Response to the Pandemic takes readers on an extraordinary journey from the medical science of viruses and vaccines, to conspiracy theories, through the history of knowledge, to the precipice—where we are now—of uncertainty about the future. This is not a book for those who think they already know how the story ends, but one that asks the tough questions in terse, hard-hitting paragraphs and chapters. Virus walks a tightrope wire, in the same way that nearly all Americans are already doing, and does not presume our lives will be saved by any one approach or answer, or that any side has ownership of the truth, but puts us on a path towards a better understanding of what just happened to us and where we&’re likely to be headed when, not if, the next virus appears. Here is: • The true story behind the triumph of science in an era of unprecedented science denialism; • The other true story of government malfeasance that brought the U.S. to its knees and saw more Americans die from the pandemic than in any other nation; • An eye-opening series of interviews with researchers and creators of the mRNA vaccine, its test subjects, and other key figures; • The history behind one of the great medical milestones: the astonishingly fast development and clinical deployment of the first mRNA vaccine, and how it will change the way medicine is practiced in the future; • The alternate reality of bizarre conspiracy theories that undergird pandemic denialism and vaccine hesitancy; • The return of eugenics and how shock doctrine capitalism, crony corruption and extreme free ideology killed people of color, the poor, and the frail; • An assessment of the lessons learned and opportunities lost and what this will mean for the future of our democracy and our people. Virus includes original research and interviews with many key figures and experts including MIT engineer (&“The Edison of Medicine&”) and Moderna founder Robert Langer, Stanford microbiologist David Relman, first mRNA clinical trial (Seattle) participant Missy Pena, medical anthropologist Martha Louise Lincoln, among many others, and a deep reading of publicly available documents and reporting.
The Virus
by Stanley JohnsonFrom renowned British politician Stanley Johnson, an exciting, intelligent thriller about the rise of a mysterious virus and one man's fight to stop a deadly pandemic, perfect for fans of Michael Crichton and Dan Brown.How do you stop an invisible killer?When a young woman in New York City dies mysteriously after a trip to Europe, top epidemiologist Lowell Kaplan identifies the cause of death as the Marburg Virus—a fatal strain that has surfaced only once before in history.Determined to trace the source of the disease, Kaplan follows a trail of intrigue from the labs of Germany to the jungles of Central Africa. But powerful forces are conspiring against him, determined to keep the secrets of the virus's origin deliberately under wraps. And with a global pandemic on the rise, Kaplan must go to unimaginable lengths to stop a deadly scheme and save mankind.
The Virus and the Vaccine: The True Story of a Cancer-Causing Monkey Virus, Contaminated Polio Vaccine, and the Millions of Americans Exposed
by Debbie Bookchin Jim SchumacherA comprehensive story of the problems and concerns associated with the polio vaccine
The Virus and the Vaccine: Contaminated Vaccine, Deadly Cancers, and Government Neglect
by Debbie Bookchin Jim SchumacherJonas Salk's polio vaccine has taken on an almost legendary quality as a medical miracle, for it largely eradicated one of the most feared diseases of the 20th century. But the story of the vaccine has a dark side, one that has never been fully told before...Between 1954 and 1963, close to 98 million Americans received polio vaccinations contaminated with a carcinogenic monkey virus, now known as SV40. A concerted government effort downplayed the incident, and it was generally accepted that although oncogenic to laboratory animals, SV40 was harmless to humans.But now SV40 in showing up in human cancers, and prominent researchers are demanding a serious public health response to this forgotten polio vaccine contaminant. A gripping medical detective story, The Virus and the Vaccine raises major questions about vaccine policy.
Virus Bioinformatics (Chapman & Hall/CRC Computational Biology Series)
by Dmitrij Frishman Manja MarzViruses are the most numerous and deadliest biological entities on the planet, infecting all types of living organisms—from bacteria to human beings. The constantly expanding repertoire of experimental approaches available to study viruses includes both low-throughput techniques, such as imaging and 3D structure determination, and modern OMICS technologies, such as genome sequencing, ribosomal profiling, and RNA structure probing. Bioinformatics of viruses faces significant challenges due to their seemingly unlimited diversity, unusual lifestyle, great variety of replication strategies, compact genome organization, and rapid rate of evolution. At the same time, it also has the potential to deliver decisive clues for developing vaccines and medications against dangerous viral outbreaks, such as the recent coronavirus pandemics. Virus Bioinformatics reviews state-of-the-art bioinformatics algorithms and recent advances in data analysis in virology. FEATURES Contributions from leading international experts in the field Discusses open questions and urgent needs Covers a broad spectrum of topics, including evolution, structure, and function of viruses, including coronaviruses The book will be of great interest to computational biologists wishing to venture into the rapidly advancing field of virus bioinformatics as well as to virologists interested in acquiring basic bioinformatics skills to support their wet lab work.
Virus Detection (Pocket Guides to Biomedical Sciences)
by Charles H. WickViruses do not behave as other microbes; their life cycles require infecting healthy cells, commandeering their cellular apparatus, replicating and then killing the host cell. Methods for virus detection and identification have been developed only in the past few decades. These recently developed methods include molecular, physical, and proteomic techniques. All these approaches (Electron Microscopy, Molecular, Direct Counting, and Mass Spectrometry Proteomics) to detection and identification are reviewed in this succinct volume. It is written in approachable language with enough detail for trained professionals to follow and want to recommend to others. Key Features Covers common detection methods Reviews the history of detection from antiquity to the present Documents the strengths and weaknesses of various detection methods Describes how to detect newly discovered viruses Recommends specific applications for clinical, hospital, environmental, and public health uses
Virus Entry Inhibitors: Stopping the Enemy at the Gate (Advances in Experimental Medicine and Biology #1366)
by Shibo Jiang Lu LuThis book focuses on the important discoveries of the small molecule-, peptide-, and protein-based virus entry inhibitors and discusses advance of the development of different type of virus entry inhibitors as a novel class of antiviral drugs for treatment and prevention of viral infection. It includes entry inhibitors of HIV,HeV, NiV, RSV, EBOV, HCoV, HBV, HCV, HDV, HPV, flavivirus and influenza virus, so on. This book aims at providing an updated knowledge on virus entry inhibitors.
Virus Ground Zero: Stalking the Killer Viruses with the Centers for Disease Control
by Ed RegisAn acclaimed science writer takes readers behind the scenes at the Centers for Disease Control to tell the story of an engrossing odyssey across the viral frontier.
Virus-Host Interactions: Methods and Protocols
by Diana Lieber Susanne M. BailerVirus-Host Interactions: Methods and Protocols covers various aspects of virological research, such as biochemical approaches, including molecular interactions and regulatory mechanisms on the protein as well as the RNA level with a strong focus on the manifold possibilities to study protein-protein interactions, as well as cell biological and immunological methodologies. Viruses represent a reduced form of life that depends on host cells for propagation. To this end, viruses approach and penetrate cells and usurp cellular machineries for their own benefit. Recent technological improvements have enabled the systematic analysis of the virus-host interplay be it on the genomic, the transcriptomic, or proteomic level. In parallel, bioinformatic tools have emerged in support of the large datasets generated by these high-throughput approaches. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Virus-Host Interactions: Methods and Protocols will prove invaluable to professionals and novices with its well-honed methodologies and protocols.
Virus-Host Interactions: Methods and Protocols (Methods in Molecular Biology #2610)
by Marilena Aquino de MuroThis detailed volume spotlights methods to investigate a variety of virus-host interactions in humans, other mammals, fish, or insects. It explores viruses such as white spot syndrome virus (WSSV), honeybee viruses, Nipah virus, EBV, SVCV, HSV-1, HIV-1, A H1N1, and SARS-CoV-2, as well as applications of techniques such as qPCR, serum antibody responses, 4C analysis, cell membrane fusion, biosensors, computational modelling, quantitative proteomics, and other genetic tools to decipher those viral infections and interactions. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Virus-Host Interactions: Methods and Protocols serves as a valuable resource for researchers both in academia and in the biosciences industry who are engaged in the search for a better understanding of threatening virus-hosts interactions, virus detection, their characterization, and ultimately their taming and control.
Virus Hybrids as Nanomaterials
by Baochuan Lin Banahalli RatnaIn Virus Hybrids as Nanomaterials: Methods and Protocols expert researchers in the field detail many of the methods used to study virus for medial and nonmedical applications. These include methods and techniques for genetically engineering viruses for therapeutic purpose and vaccine production, chemically modified viruses for virus-templated nanoparticles production, and genetically engineered or chemically modified viral particles as imaging agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Virus Hybrids as Nanomaterials: Methods and Protocols seek to aid new researchers to get involved in this multidisciplinary area.
The Virus in the Age of Madness
by Bernard-Henri LevyAs seen on CNN's Fareed Zakaria GPS Forget the world that came before. The author of American Vertigo serves up an incisive look at how COVID-19 reveals the dangerous fault lines of contemporary society. With medical mysteries, rising death tolls, and conspiracy theories beamed minute by minute through the vast web universe, the coronavirus pandemic has irrevocably altered societies around the world. In this sharp essay, world-renowned philosopher Bernard-Henri Lévy interrogates the many meanings and metaphors we have assigned to the pandemic—and what they tell us about ourselves. Drawing on the philosophical tradition from Plato and Aristotle to Lacan and Foucault, Lévy asks uncomfortable questions about reality and mythology: he rejects the idea that the virus is a warning from nature, the inevitable result of global capitalism; he questions the heroic status of doctors, asking us to think critically about the loci of authority and power; he challenges the panicked polarization that dominates online discourse. Lucid, incisive, and always original, Lévy takes a bird&’s-eye view of the most consequential historical event of our time and proposes a way to defend human society from threats to our collective future.